Autor: "Tai, ES" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis.
Autorzy:: Wheeler E; Department of Human Genetics, Wellcome Trust Sanger Institute, Genome Campus, Hinxton, Cambridge, United Kingdom.
Leong A; Division of General Internal Medicine, Massachusetts General Hospital, Boston, MA, United States of America.; Harvard Medical School, Boston, MA, United States of America.
Liu CT; Department of Biostatistics, Boston University School of Public Health, Boston, MA, United States of America.
Hivert MF; Department of Population Medicine, Harvard Medical School, Harvard Pilgrim Health Care Institute, Boston, MA, United States of America.; Massachusetts General Hospital, Boston, MA, United States of America.
Strawbridge RJ; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.; Centre for Molecular Medicine, Karolinska Universitetsjukhuset, Solna, Sweden.
Podmore C; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom.; Department of Internal Medicine, Lausanne University Hospital (CHUV), Lausanne, Switzerland.
Li M; Department of Epidemiology, The Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States of America.; Division of Nephrology, University of Utah, Salt Lake City, UT, United States of America.; Department of Human Genetics, University of Utah, Salt Lake City, UT, United States of America.
Yao J; Institute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, United States of America.
Sim X; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.
Hong J; Department of Biostatistics, Boston University School of Public Health, Boston, MA, United States of America.
Chu AY; National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, MA, United States of America.; Division of Preventive Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States of America.
Zhang W; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom.; Department of Cardiology, Ealing Hospital NHS Trust, Southall, Middlesex, United Kingdom.
Wang X; Life Sciences Institute, National University of Singapore, Singapore, Singapore.
Chen P; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.; Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, AZ, United States of America.; Key Laboratory of Pathobiology, Ministry of Education, Jilin University, Changchun, Jilin, China.; College of Basic Medical Sciences, Jilin University, Changchun, Jilin, China.
Maruthur NM; Department of Epidemiology, The Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States of America.; Division of General Internal Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, United States of America.; Welch Center for Prevention, Epidemiology and Clinical Research, The Johns Hopkins University, Baltimore, MD, United States of America.
Porneala BC; Division of General Internal Medicine, Massachusetts General Hospital, Boston, MA, United States of America.
Sharp SJ; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom.
Jia Y; Institute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, United States of America.
Kabagambe EK; Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, United States of America.
Chang LC; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.
Chen WM; University of Virginia Center for Public Health Genomics, Charlottesville, VA, United States of America.
Elks CE; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom.; Personalised Healthcare & Biomarkers, Innovative Medicines and Early Development Biotech Unit, AstraZeneca, Cambridge, United Kingdom.
Evans DS; California Pacific Medical Center Research Institute, San Francisco, CA, United States of America.
Fan Q; Centre for Quantitative Medicine, Duke-NUS Medical School, Singapore, Singapore.
Giulianini F; Division of Preventive Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States of America.
Go MJ; Division of Structural and Functional Genomics, Center for Genome Science, Korean National Institute of Health, Osong, Chungchungbuk-do, South Korea.
Hottenga JJ; Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
Hu Y; The Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, University of the Chinese Academy of Sciences, Shanghai, People's Republic of China.
Jackson AU; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, United States of America.
Kanoni S; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.
Kim YJ; Division of Structural and Functional Genomics, Center for Genome Science, Korean National Institute of Health, Osong, Chungchungbuk-do, South Korea.
Kleber ME; Vth Department of Medicine, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.
Ladenvall C; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.; Lund University Diabetes Centre, Lund University, Lund, Sweden.
Lecoeur C; University of Lille, CNRS, Institut Pasteur of Lille, UMR 8199-EGID, Lille, France.
Lim SH; Singapore Eye Research Institute, The Academia Level 6, Discovery Tower, Singapore, Singapore.
Lu Y; The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, NY, United States of America.; The Genetics of Obesity and Related Metabolic Traits Program, The Icahn School of Medicine at Mount Sinai, New York, NY, United States of America.
Mahajan A; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.
Marzi C; Institute of Epidemiology II, Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; German Center for Diabetes Research (DZD e.V.), Partner Munich, Munich, Germany.
Nalls MA; Data Tecnica International, Glen Echo, MD, United States of America.; Laboratory of Neurogenetics, National Institute on Aging, Bethesda, MD, United States of America.
Navarro P; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland.
Nolte IM; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.
Rose LM; Division of Preventive Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States of America.
Rybin DV; Department of Biostatistics, Boston University School of Public Health, Boston, MA, United States of America.; Data Coordinating Center, Boston University School of Public Health, Boston, MA, United States of America.
Sanna S; Istituto di Ricerca Genetica e Biomedica (IRGB), CNR, Monserrato, Italy.
Shi Y; Singapore Eye Research Institute, The Academia Level 6, Discovery Tower, Singapore, Singapore.
Stram DO; Department of Preventive Medicine, University of Southern California, Los Angeles, CA, United States of America.
Takeuchi F; Department of Gene Diagnostics and Therapeutics, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan.
Tan SP; Singapore Eye Research Institute, The Academia Level 6, Discovery Tower, Singapore, Singapore.
van der Most PJ; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.
Van Vliet-Ostaptchouk JV; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.; Department of Endocrinology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.
Wong A; MRC Unit for Lifelong Health & Ageing, London, United Kingdom.
Yengo L; University of Lille, CNRS, Institut Pasteur of Lille, UMR 8199-EGID, Lille, France.
Zhao W; Singapore Eye Research Institute, The Academia Level 6, Discovery Tower, Singapore, Singapore.
Goel A; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom.
Martinez Larrad MT; Spanish Biomedical Research Centre in Diabetes and Associated Metabolic Disorders (CIBERDEM), Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Madrid, Spain.
Radke D; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.
Salo P; National Institute for Health and Welfare (THL), Helsinki, Finland.; University of Helsinki, Institute for Molecular Medicine, Finland (FIMM) and Diabetes and Obesity Research Program, Helsinki, Finland.
Tanaka T; Translational Gerontology Branch, National Institute on Aging, Baltimore, MD, United States of America.
van Iperen EPA; Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands.; Durrer Center for Cardiogenetic Research, ICIN-Netherlands Heart Institute, Utrecht, Netherlands.
Abecasis G; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, United States of America.
Afaq S; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom.
Alizadeh BZ; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.
Bertoni AG; Department of Epidemiology and Prevention, Wake Forest School of Medicine, Winston-Salem, NC, United States of America.
Bonnefond A; University of Lille, CNRS, Institut Pasteur of Lille, UMR 8199-EGID, Lille, France.
Böttcher Y; Integrated Research and Treatment (IFB) Center Adiposity Diseases, University of Leipzig, Leipzig, Germany.
Bottinger EP; The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, NY, United States of America.
Campbell H; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland.
Carlson OD; Laboratory of Clinical Investigation, National Institute on Aging, Baltimore, MD, United States of America.
Chen CH; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.; School of Chinese Medicine, China Medical University, Taichung City, Taiwan.
Cho YS; Division of Structural and Functional Genomics, Center for Genome Science, Korean National Institute of Health, Osong, Chungchungbuk-do, South Korea.; Department of Biomedical Science, Hallym University, Chuncheon, Gangwon-do, South Korea.
Garvey WT; Department of Nutrition Sciences, University of Alabama at Birmingham and the Birmingham Veterans Affairs Medical Center, Birmingham, AL, United States of America.
Gieger C; Institute of Epidemiology II, Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.
Goodarzi MO; Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, United States of America.
Grallert H; Institute of Epidemiology II, Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; German Center for Diabetes Research (DZD e.V.), Partner Munich, Munich, Germany.
Hamsten A; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.; Centre for Molecular Medicine, Karolinska Universitetsjukhuset, Solna, Sweden.
Hartman CA; Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.
Herder C; Institute for Clinical Diabetology, German Diabetes Center, Leibniz Institute for Diabetes Research at Heinrich Heine University Düsseldorf, Düsseldorf, Germany.; German Center for Diabetes Research (DZD), München-Neuherberg, Germany.
Hsiung CA; Division of Endocrinology, Diabetes, Metabolism, Department of Internal Medicine, Wexner Medical Center, The Ohio State University, Columbus, OH, United States of America.
Huang J; Boston VA Research Institute, Inc., Boston, MA, United States of America.
Igase M; Department of Geriatric Medicine, Ehime University Graduate School of Medicine, Ehime, Japan.
Isono M; Department of Gene Diagnostics and Therapeutics, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan.
Katsuya T; Department of Clinical Gene Therapy, Osaka University Graduate School of Medicine, Suita, Japan.; Department of Geriatric Medicine and Nephrology, Osaka University Graduate School of Medicine, Suita, Japan.
Khor CC; Genome Institute of Singapore, Agency for Science Technology and Research, Singapore, Singapore.
Kiess W; Center of Pediatric Research, University Hospital for Children & Adolescents, Dept. of Women's & Child Health, University of Leipzig, Leipzig, Germany.; LIFE Child, LIFE Leipzig Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany.
Kohara K; Faculty of Collaborative Regional Innovation, Ehime University, Ehime, Japan.
Kovacs P; Integrated Research and Treatment (IFB) Center Adiposity Diseases, University of Leipzig, Leipzig, Germany.
Lee J; Division of Structural and Functional Genomics, Center for Genome Science, Korean National Institute of Health, Osong, Chungchungbuk-do, South Korea.
Lee WJ; Department of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan.
Lehne B; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom.
Li H; The Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, University of the Chinese Academy of Sciences, Shanghai, People's Republic of China.
Liu J; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.; Genome Institute of Singapore, Agency for Science Technology and Research, Singapore, Singapore.
Lobbens S; University of Lille, CNRS, Institut Pasteur of Lille, UMR 8199-EGID, Lille, France.
Luan J; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom.
Lyssenko V; Lund University Diabetes Centre, Lund University, Lund, Sweden.
Meitinger T; Institute of Human Genetics, Technische Universität München, Munich, Germany.; Institute of Human Genetics, Helmholtz Zentrum München, Neuherberg, Germany.; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.
Miki T; Department of Geriatric Medicine, Ehime University Graduate School of Medicine, Ehime, Japan.
Miljkovic I; Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, United States of America.
Moon S; Division of Structural and Functional Genomics, Center for Genome Science, Korean National Institute of Health, Osong, Chungchungbuk-do, South Korea.
Mulas A; Istituto di Ricerca Genetica e Biomedica (IRGB), CNR, Monserrato, Italy.
Müller G; Center for Evidence-based Healthcare, University Hospital and Medical Faculty Carl Gustav Carus, Dresden, Germany.
Müller-Nurasyid M; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Department of Medicine I, University Hospital Grosshadern, Ludwig-Maximilians-Universität, Munich, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany.
Nagaraja R; Laboratory of Genetics, National Institute on Aging, Baltimore, MD, United States of America.
Nauck M; Institute for Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany.
Pankow JS; Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN, United States of America.
Polasek O; University of Split, Split, Croatia.; Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom.
Prokopenko I; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom.; Department of Genomics of Common Disease, School of Public Health, Imperial College London, London, United Kingdom.
Ramos PS; Department of Medicine, Medical University of South Carolina, Charleston, SC, United States of America.
Rasmussen-Torvik L; Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, United States of America.
Rathmann W; German Center for Diabetes Research (DZD), München-Neuherberg, Germany.
Rich SS; Center for Public Health Genomics, University of Virginia School of Medicine, Charlottesville, VA, United States of America.
Robertson NR; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom.; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
Roden M; Institute for Clinical Diabetology, German Diabetes Center, Leibniz Institute for Diabetes Research at Heinrich Heine University Düsseldorf, Düsseldorf, Germany.; German Center for Diabetes Research (DZD), München-Neuherberg, Germany.; Department of Endocrinology and Diabetology, University Hospital Düsseldorf, Düsseldorf, Germany.
Roussel R; INSERM, UMR_S 1138, Centre de Recherche des Cordelier, Paris, France.; Université Paris Diderot, Sorbonne Paris Cité, UFR de Médecine, Paris, France.; Assistance Publique Hôpitaux de Paris, Bichat Hospital, DHU FIRE, Department of Diabetology, Endocrinology and Nutrition, Paris, France.
Rudan I; University of Edinburgh, Edinburgh, United Kingdom.
Scott RA; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom.
Scott WR; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom.; Department of Cardiology, Ealing Hospital NHS Trust, Southall, Middlesex, United Kingdom.
Sennblad B; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.; Centre for Molecular Medicine, Karolinska Universitetsjukhuset, Solna, Sweden.; Science for life laboratory, Karolinska Institutet, Solna, Sweden.
Siscovick DS; The New York Academy of Medicine, New York, NY, United States of America.
Strauch K; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Medical Informatics, Biometry and Epidemiology, Ludwig-Maximilians-Universität, Munich, Germany.
Sun L; The Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, University of the Chinese Academy of Sciences, Shanghai, People's Republic of China.
Swertz M; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.
Tajuddin SM; Health Disparities Unit, National Institute on Aging, National Institutes of Health, Baltimore, MD, United States of America.
Taylor KD; Institute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, United States of America.
Teo YY; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.; Life Sciences Institute, National University of Singapore, Singapore, Singapore.; Genome Institute of Singapore, Agency for Science Technology and Research, Singapore, Singapore.; Department of Statistics and Applied Probability, National University of Singapore, Singapore, Singapore.; NUS Graduate School for Integrative Science and Engineering, National University of Singapore, Singapore, Singapore.
Tham YC; Singapore Eye Research Institute, The Academia Level 6, Discovery Tower, Singapore, Singapore.
Tönjes A; Department of Medicine; University of Leipzig, Leipzig, Germany.
Wareham NJ; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom.
Willemsen G; Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
Wilsgaard T; Dept of Community Medicine, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway.
Hingorani AD; Institute of Cardiovascular Science, University College London, London, United Kingdom.
Egan J; Laboratory of Clinical Investigation, National Institute on Aging, Baltimore, MD, United States of America.
Ferrucci L; Laboratory of Clinical Investigation, National Institute on Aging, Baltimore, MD, United States of America.
Hovingh GK; Department of Vascular Medicine, Academic Medical Center, Amsterdam, Netherlands.
Jula A; National Institute for Health and Welfare (THL), Helsinki, Finland.
Kivimaki M; Department of Epidemiology and Public Health, University College London, London, United Kingdom.
Kumari M; Department of Epidemiology and Public Health, University College London, London, United Kingdom.; Institute for Social and Economic Research, University of Essex, Colchester, United Kingdom.
Njølstad I; Dept of Community Medicine, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway.
Palmer CNA; Pat Macpherson Centre for Pharmacogenetics and Pharmacogenomics, Medical Research Institute, Ninewells Hospital and Medical School, Dundee, United Kingdom.
Serrano Ríos M; Spanish Biomedical Research Centre in Diabetes and Associated Metabolic Disorders (CIBERDEM), Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Madrid, Spain.
Stumvoll M; Department of Medicine; University of Leipzig, Leipzig, Germany.
Watkins H; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom.
Aung T; Singapore Eye Research Institute, The Academia Level 6, Discovery Tower, Singapore, Singapore.; Ophthalmology and Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Singapore National Eye Centre, Singapore, Singapore.
Blüher M; Department of Medicine; University of Leipzig, Leipzig, Germany.
Boehnke M; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, United States of America.
Boomsma DI; Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
Bornstein SR; Dept of Medicine III, University of Dresden, Medical Faculty Carl Gustav Carus, Dresden, Germany.
Chambers JC; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom.; Department of Cardiology, Ealing Hospital NHS Trust, Southall, Middlesex, United Kingdom.; Imperial College Healthcare NHS Trust, London, United Kingdom.
Chasman DI; Division of Preventive Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States of America.; Division of Genetics, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States of America.; Broad Institute of MIT and Harvard, Cambridge, MA, United States of America.
Chen YI; Institute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, United States of America.
Chen YT; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.
Cheng CY; Singapore Eye Research Institute, The Academia Level 6, Discovery Tower, Singapore, Singapore.; Ophthalmology and Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Singapore National Eye Centre, Singapore, Singapore.
Cucca F; Istituto di Ricerca Genetica e Biomedica (IRGB), CNR, Monserrato, Italy.; Dipartimento di Scienze Biomediche, Università di Sassari, Italy.
de Geus EJC; Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
Deloukas P; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.; Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders (PACER-HD), King Abdulaziz University, Jeddah, Saudi Arabia.
Evans MK; Health Disparities Unit, National Institute on Aging, National Institutes of Health, Baltimore, MD, United States of America.
Fornage M; Brown Foundation Institute of Molecular Medicine, Division of Epidemiology, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, United States of America.
Friedlander Y; Braun School of Public Health, Hebrew University-Hadassah Medical Center, Jerusalem, Israel.
Froguel P; Department of Genomics of Common Disease, School of Public Health, Imperial College London, London, United Kingdom.; CNRS 8199-Lille University, France.
Groop L; Lund University Diabetes Centre, Lund University, Lund, Sweden.; Finnish Institute for Molecular Medicine (FIMM), Helsinki, Finland.
Gross MD; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN, United States of America.
Harris TB; National Institute on Aging, Bethesda, MD, United States of America.
Hayward C; Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom.
Heng CK; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Khoo Teck Puat-National University Children's Medical Institute, National University Health System, Singapore, Singapore.
Ingelsson E; Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.; Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, United States of America.
Kato N; Department of Gene Diagnostics and Therapeutics, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan.
Kim BJ; Division of Structural and Functional Genomics, Center for Genome Science, Korean National Institute of Health, Osong, Chungchungbuk-do, South Korea.
Koh WP; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.; Duke-NUS Medical School Singapore, Singapore.
Kooner JS; Department of Cardiology, Ealing Hospital NHS Trust, Southall, Middlesex, United Kingdom.; Imperial College Healthcare NHS Trust, London, United Kingdom.; National Heart and Lung Institute, Imperial College London, Hammersmith Hospital Campus, London, United Kingdom.
Körner A; Center of Pediatric Research, University Hospital for Children & Adolescents, Dept. of Women's & Child Health, University of Leipzig, Leipzig, Germany.; LIFE Child, LIFE Leipzig Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany.
Kuh D; MRC Unit for Lifelong Health & Ageing, London, United Kingdom.
Kuusisto J; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland.
Laakso M; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland.
Lin X; The Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, University of the Chinese Academy of Sciences, Shanghai, People's Republic of China.
Liu Y; Department of Epidemiology and Prevention, Division of Public Health Sciences, Wake Forest University, Winston-Salem, NC, United States of America.
Loos RJF; The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, NY, United States of America.; The Genetics of Obesity and Related Metabolic Traits Program, The Icahn School of Medicine at Mount Sinai, New York, NY, United States of America.; The Mindich Child Health Development Institute, The Icahn School of Medicine at Mount Sinai, New York, NY, United States of America.
Magnusson PKE; Department of Medical Epidemiology and Biostatistics, Karolinska Insitutet, Stockholm, Sweden.
März W; Vth Department of Medicine, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.; Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria.; Synlab Academy, Synlab Services GmbH, Mannheim, Germany.
McCarthy MI; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom.; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, United Kingdom.
Oldehinkel AJ; Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.
Ong KK; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom.
Pedersen NL; Department of Medical Epidemiology and Biostatistics, Karolinska Insitutet, Stockholm, Sweden.
Pereira MA; Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN, United States of America.
Peters A; Institute of Epidemiology II, Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.
Ridker PM; Division of Preventive Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States of America.; Division of Cardiovascular Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States of America.
Sabanayagam C; Singapore Eye Research Institute, The Academia Level 6, Discovery Tower, Singapore, Singapore.; Ophthalmology and Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore.
Sale M; Center for Public Health Genomics, University of Virginia School of Medicine, Charlottesville, VA, United States of America.
Saleheen D; Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA, United States of America.; Center for Non-Communicable Diseases, Karachi, Pakistan.
Saltevo J; Department of Medicine, Central Hospital, Central Finland, Jyväskylä, Finland.
Schwarz PE; Dept of Medicine III, University of Dresden, Medical Faculty Carl Gustav Carus, Dresden, Germany.
Sheu WHH; Division of Endocrine and Metabolism, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.; School of Medicine, National Yang-Ming University, Taipei, Taiwan.; School of Medicine, National Defense Medical Center, Taipei, Taiwan.
Snieder H; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.
Spector TD; Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom.
Tabara Y; Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Tuomilehto J; Chronic Disease Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland.; Dasman Diabetes Institute, Dasman, Kuwait.; Centre for Vascular Prevention, Danube-University Krems, Krems, Austria.; Saudi Diabetes Research Group, King Abdulaziz University, Fahd Medical Research Center, Jeddah, Saudi Arabia.
van Dam RM; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.
Wilson JG; Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, MS, United States of America.
Wilson JF; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland.; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland.
Wolffenbuttel BHR; Department of Endocrinology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.
Wong TY; Singapore Eye Research Institute, The Academia Level 6, Discovery Tower, Singapore, Singapore.; Ophthalmology and Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Singapore National Eye Centre, Singapore, Singapore.
Wu JY; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.; School of Chinese Medicine, China Medical University, Taichung City, Taiwan.
Yuan JM; Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, United States of America.; Division of Cancer Control and Population Sciences,University of Pittsburgh Cancer Institute, Pittsburgh, PA, United States of America.
Zonderman AB; Laboratory of Epidemiology & Population Sciences, National Institute on Aging, National Institutes of Health, Baltimore, MD, United States of America.
Soranzo N; Department of Human Genetics, Wellcome Trust Sanger Institute, Genome Campus, Hinxton, Cambridge, United Kingdom.; Department of Haematology, University of Cambridge, Cambridge, United Kingdom.; The National Institute for Health Research Blood and Transplant Unit (NIHR BTRU) in Donor Health and Genomics at the University of Cambridge, United Kingdom.
Guo X; Institute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, United States of America.
Roberts DJ; Biomedical Research Centre Oxford Haematology Theme and Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Headley Way, Headington, Oxford, United Kingdom.; NHS Blood and Transplant, Headington, Oxford, United Kingdom.
Florez JC; Harvard Medical School, Boston, MA, United States of America.; Diabetes Unit and Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA, United States of America.; Programs in Metabolism and Medical & Population Genetics, Broad Institute, Cambridge, MA, United States of America.
Sladek R; Department of Medicine, McGill University, Montreal, Quebec, Canada.
Dupuis J; Department of Biostatistics, Boston University School of Public Health, Boston, MA, United States of America.; National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, MA, United States of America.
Morris AP; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.; Department of Biostatistics, University of Liverpool, Liverpool, United Kingdom.
Tai ES; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.; Duke-NUS Medical School Singapore, Singapore.; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Selvin E; Department of Epidemiology, The Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States of America.; Division of General Internal Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, United States of America.; Welch Center for Prevention, Epidemiology and Clinical Research, The Johns Hopkins University, Baltimore, MD, United States of America.
Rotter JI; Institute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, United States of America.
Langenberg C; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom.
Barroso I; Department of Human Genetics, Wellcome Trust Sanger Institute, Genome Campus, Hinxton, Cambridge, United Kingdom.; Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom.
Meigs JB; Division of General Internal Medicine, Massachusetts General Hospital, Boston, MA, United States of America.; Harvard Medical School, Boston, MA, United States of America.; Programs in Metabolism and Medical & Population Genetics, Broad Institute, Cambridge, MA, United States of America.; Pokaż więcej
Corporate Authors:: EPIC-CVD Consortium
EPIC-InterAct Consortium
Lifelines Cohort Study
Źródło:: PLoS medicine [PLoS Med] 2017 Sep 12; Vol. 14 (9), pp. e1002383. Date of Electronic Publication: 2017 Sep 12 (Print Publication: 2017).
Typ publikacji:: Journal Article; Meta-Analysis
MeSH Terms:: Genetic Variation*
Genome-Wide Association Study*
Diabetes Mellitus, Type 2/*diagnosis
Diabetes Mellitus, Type 2/*genetics
Glycated Hemoglobin/*genetics
Diabetes Mellitus, Type 2/epidemiology ; Glycated Hemoglobin/metabolism ; Humans ; Phenotype ; Risk

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Skocz do pozycji: 2.

Tytuł:: Genome-wide association studies in East Asians identify new loci for waist-hip ratio and waist circumference.
Autorzy:: Wen W; Department of Epidemiology, Vanderbilt University School of Medicine, Nashville, Tennessee 37203, USA.
Kato N; Department of Gene Diagnostics and Therapeutics, Research Institute, National Center for Global Health and Medicine, Shinjuku-ku, Tokyo 1628655, Japan.
Hwang JY; Center for Genome Science, National Institute of Health, Osong Health Technology Administration Complex, Chungcheongbuk-do, Republic of Korea.
Guo X; Department of Epidemiology, Vanderbilt University School of Medicine, Nashville, Tennessee 37203, USA.
Tabara Y; Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.; Department of Geriatric Medicine, Ehime University Graduate School of Medicine, Ehime, Japan.
Li H; Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China.
Dorajoo R; Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore.
Yang X; Center for Genomic and Personalized Medicine, Guangxi Medical University, Nanning, Guangxi, China.; Department of Occupational Health and Environmental Health, School of Public Health, Guangxi Medical University, Nanning, Guangxi, China.
Tsai FJ; School of Chinese Medicine, China Medical University, Taichung, Taiwan.; Department of Medical Genetics, China Medical University Hospital, Taichung, Taiwan.; Department of Health and Nutrition Biotechnology, Asia University, Taichung, Taiwan.
Li S; Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana, USA.
Wu Y; Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599, USA.
Wu T; Key Laboratory of Environment and Health, Ministry of Education, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Kim S; Institute for Health Promotion, Yonsei University, Seodaemun-Gu, Seoul 120-749, Korea.
Guo X; Institute for Translational Genomics and Population Sciences, Department of Pediatrics and Medicine, LABioMed at Harbor-UCLA Medical Center, Torrance, California, USA.
Liang J; Department of Endocrinology, the Central Hospital of Xuzhou, Affiliated Hospital of Southeast University, Xuzhou, Jiangsu, China.
Shungin D; Department of Clinical Sciences, Genetic &Molecular Epidemiology Unit, Lund University Diabetes Center, Skåne University Hospital, Malmö 205 02, Sweden.; Department of Public Health and Clinical Medicine, Unit of Medicine, Umeå University, Umeå 901 87, Sweden.
Adair LS; Department of Medical Chemistry, Kurume University School of Medicine, Kurume, Fukuoka 830-0011, Japan.
Akiyama K; State Key Laboratory of Molecular Oncology, Cancer Institute &Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Allison M; Division of Preventive Medicine, Department of Family and Preventive Medicine, University of California, San Diego School of Medicine, San Diego, California, USA.
Cai Q; Department of Epidemiology, Vanderbilt University School of Medicine, Nashville, Tennessee 37203, USA.
Chang LC; National Center for Genome Medicine, Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.
Chen CH; National Center for Genome Medicine, Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.; School of Chinese Medicine, China Medical University, Taichung, Taiwan.
Chen YT; National Center for Genome Medicine, Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.
Cho YS; Center for Genome Science, National Institute of Health, Osong Health Technology Administration Complex, Chungcheongbuk-do, Republic of Korea.; Department of Biomedical Science, Hallym University, Gangwon-do, Korea.
Choi BY; Department of Preventive Medicine, College of Medicine, Hanyang University, Seoul, Korea.
Gao Y; Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Go MJ; Center for Genome Science, National Institute of Health, Osong Health Technology Administration Complex, Chungcheongbuk-do, Republic of Korea.
Gu D; Division of Population Genetics, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Han BG; Center for Genome Science, National Institute of Health, Osong Health Technology Administration Complex, Chungcheongbuk-do, Republic of Korea.
He M; Key Laboratory of Environment and Health, Ministry of Education, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Hixson JE; Human Genetics Center, University of Texas School of Public Health, Houston, Texas, USA.
Hu Y; Center for Genomic and Personalized Medicine, Guangxi Medical University, Nanning, Guangxi, China.; Medical Scientific Research Center, Guangxi Medical University, Nanning, Guangxi 530021, China.
Huang T; Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA.
Isono M; Department of Gene Diagnostics and Therapeutics, Research Institute, National Center for Global Health and Medicine, Shinjuku-ku, Tokyo 1628655, Japan.
Jung KJ; Institute for Health Promotion, Yonsei University, Seodaemun-Gu, Seoul 120-749, Korea.
Kang D; Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, Korea.
Kim YJ; Center for Genome Science, National Institute of Health, Osong Health Technology Administration Complex, Chungcheongbuk-do, Republic of Korea.
Kita Y; Department of Nursing, Tsuruga University of Nursing, Tsuruga, Japan.
Lee J; Center for Genome Science, National Institute of Health, Osong Health Technology Administration Complex, Chungcheongbuk-do, Republic of Korea.
Lee NR; Office of Population Studies Foundation Inc., University of San Carlos, Talamban, Cebu City, Philippines.
Lee J; Saw Swee Hock School of Public Health, National University of Singapore, Singapore.
Wang Y; Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China.
Liu JJ; Saw Swee Hock School of Public Health, National University of Singapore, Singapore.; Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore.
Long J; Department of Epidemiology, Vanderbilt University School of Medicine, Nashville, Tennessee 37203, USA.
Moon S; Center for Genome Science, National Institute of Health, Osong Health Technology Administration Complex, Chungcheongbuk-do, Republic of Korea.
Nakamura Y; Department of Health Science, Shiga University of Medical Science, Shiga, Japan.; Cardiovascular Epidemiology, Kyoto Women's University, Kyoto, Japan.
Nakatochi M; Bioinformatics Section, Center for Advanced Medicine and Clinical Research, Nagoya University Hospital, Showa-ku, Nagoya 466-8560, Japan.
Ohnaka K; Department of Geriatric Medicine, Graduate School of Medical Sciences, Kyushu University, Higashi-ku, Fukuoka 812-8582, Japan.
Rao D; Division of Biostatistics, Washington University School of Medicine, St. Louis, Missouri, USA.
Shi J; Department of Epidemiology, Vanderbilt University School of Medicine, Nashville, Tennessee 37203, USA.
Sull JW; Eulji University, Seongnam City, Gyeonggi-do, Korea.
Tan A; Center for Genomic and Personalized Medicine, Guangxi Medical University, Nanning, Guangxi, China.; Department of Chemotherapy, The Affiliated Tumor Hospital of Guangxi Medical University, Nanning 530021, Guangxi, China.
Ueshima H; Department of Health Science, Shiga University of Medical Science, Shiga, Japan.; Center for Epidemiologic Research in Asia, Shiga University of Medical Science, Shiga, Japan.
Wu C; State Key Laboratory of Molecular Oncology, Cancer Institute &Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Xiang YB; Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Yamamoto K; Department of Medical Chemistry, Kurume University School of Medicine, Kurume, Fukuoka 830-0011, Japan.
Yao J; Institute for Translational Genomics and Population Sciences, Department of Pediatrics and Medicine, LABioMed at Harbor-UCLA Medical Center, Torrance, California, USA.
Ye X; Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China.
Yokota M; Department of Genome Science, Aichi-Gakuin University, School of Dentistry, Chikusa-ku, Nagoya, 464-8651, Japan.
Zhang X; Key Laboratory of Environment and Health, Ministry of Education, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Zheng Y; Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA.
Qi L; Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA.
Rotter JI; Institute for Translational Genomics and Population Sciences, Department of Pediatrics and Medicine, LABioMed at Harbor-UCLA Medical Center, Torrance, California, USA.
Jee SH; Institute for Health Promotion, Yonsei University, Seodaemun-Gu, Seoul 120-749, Korea.
Lin D; State Key Laboratory of Molecular Oncology, Cancer Institute &Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Mohlke KL; Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599, USA.
He J; Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana, USA.
Mo Z; Center for Genomic and Personalized Medicine, Guangxi Medical University, Nanning, Guangxi, China.; Institute of Urology and Nephrology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Wu JY; National Center for Genome Medicine, Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.; School of Chinese Medicine, China Medical University, Taichung, Taiwan.
Tai ES; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; Saw Swee Hock School of Public Health, National University of Singapore, Singapore.; Duke-National University of Singapore Graduate Medical School, Singapore.
Lin X; Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China.
Miki T; Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.; Department of Geriatric Medicine, Ehime University Graduate School of Medicine, Ehime, Japan.
Kim BJ; Center for Genome Science, National Institute of Health, Osong Health Technology Administration Complex, Chungcheongbuk-do, Republic of Korea.
Takeuchi F; Department of Gene Diagnostics and Therapeutics, Research Institute, National Center for Global Health and Medicine, Shinjuku-ku, Tokyo 1628655, Japan.
Zheng W; Department of Epidemiology, Vanderbilt University School of Medicine, Nashville, Tennessee 37203, USA.
Shu XO; Department of Epidemiology, Vanderbilt University School of Medicine, Nashville, Tennessee 37203, USA.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2016 Jan 20; Vol. 6, pp. 17958. Date of Electronic Publication: 2016 Jan 20.
Typ publikacji:: Journal Article; Meta-Analysis; Research Support, N.I.H., Extramural
MeSH Terms:: Genome-Wide Association Study*
Quantitative Trait Loci*
Quantitative Trait, Heritable*
Waist Circumference*
Waist-Hip Ratio*
Asian People/*genetics
Asia ; Female ; Genetic Predisposition to Disease ; Humans ; Male ; Obesity/genetics ; Polymorphism, Single Nucleotide ; Sex Factors

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Skocz do pozycji: 3.

Tytuł:: Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation.
Autorzy:: Kato N; Department of Gene Diagnostics and Therapeutics, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan.
Loh M; Institute of Health Sciences, University of Oulu, Oulu, Finland.; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Translational Laboratory in Genetic Medicine, Agency for Science, Technology and Research (ASTAR), Singapore.
Takeuchi F; Department of Gene Diagnostics and Therapeutics, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan.
Verweij N; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
Wang X; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore.
Zhang W; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Ealing Hospital National Health Service (NHS) Trust, Middlesex, UK.
Kelly TN; Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana, USA.
Saleheen D; Center for Non-Communicable Diseases, Karachi, Pakistan.; Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory, Cambridge, UK.; Cardiovascular Institute, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Lehne B; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.
Leach IM; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
Drong AW; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.
Abbott J; Bioinformatics Support Service, Imperial College London, London, UK.
Wahl S; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany.
Tan ST; Ealing Hospital National Health Service (NHS) Trust, Middlesex, UK.; National Heart and Lung Institute, Imperial College London, London, UK.
Scott WR; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; National Heart and Lung Institute, Imperial College London, London, UK.
Campanella G; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.
Chadeau-Hyam M; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.
Afzal U; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Ealing Hospital National Health Service (NHS) Trust, Middlesex, UK.
Ahluwalia TS; Novo Nordisk Foundation Centre for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Copenhagen Prospective Studies on Asthma in Childhood (COSPAC), Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.; Steno Diabetes Center, Gentofte, Denmark.
Bonder MJ; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
Chen P; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore.
Dehghan A; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands.
Edwards TL; Vanderbilt Epidemiology Center, Center for Human Genetics Research, Division of Epidemiology, Department of Medicine, Vanderbilt University, Nashville, Tennessee, USA.
Esko T; Estonian Genome Center, University of Tartu, Tartu, Estonia.; Division of Endocrinology, Children's Hospital Boston, Boston, Massachusetts, USA.; Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA.; Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, USA.
Go MJ; Center for Genome Science, National Institute of Health, Osong Health Technology Administration Complex, Chungcheongbuk-do, Republic of Korea.
Harris SE; Medical Genetics Section, University of Edinburgh Centre for Genomic and Experimental Medicine and Medical Research Council (MRC) Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, UK.; Centre for Cognitive Aging and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.
Hartiala J; Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, California, USA.; Institute for Genetic Medicine, University of Southern California Keck School of Medicine, Los Angeles, California, USA.
Kasela S; Estonian Genome Center, University of Tartu, Tartu, Estonia.
Kasturiratne A; Department of Public Health, Faculty of Medicine, University of Kelaniya, Ragama, Sri Lanka.
Khor CC; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore.; Genome Institute of Singapore, ASTAR, Singapore.; Department of Ophthalmology, National University of Singapore, Singapore.; Department of Paediatrics, National University of Singapore, Singapore.
Kleber ME; Medical Clinic V, Mannheim Medical Faculty, University of Heidelberg, Mannheim, Germany.
Li H; Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China.
Yu Mok Z; Cancer Science Institute of Singapore, National University of Singapore, Singapore.
Nakatochi M; Center for Advanced Medicine and Clinical Research, Nagoya University Hospital, Nagoya, Japan.
Sapari NS; Cancer Science Institute of Singapore, National University of Singapore, Singapore.
Saxena R; Center for Human Genetic Research, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Stewart AFR; University of Ottawa Heart Institute, Cardiovascular Research Methods Centre, Ottawa, Ontario, Canada.; Ruddy Canadian Cardiovascular Genetics Centre, Ottawa, Ontario, Canada.
Stolk L; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands.
Tabara Y; Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Teh AL; Singapore Institute for Clinical Sciences (SICS), ASTAR, Singapore.
Wu Y; Department of Genetics, University of North Carolina, Chapel Hill, North Carolina, USA.
Wu JY; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.; School of Chinese Medicine, China Medical University, Taichung, Taiwan.
Zhang Y; State Key Laboratory of Medical Genetics, Shanghai Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai Institute of Hypertension, Shanghai, China.
Aits I; Institute of Epidemiology and Biobank popgen, Christian Albrechts University of Kiel, Kiel, Germany.
Da Silva Couto Alves A; Department of Epidemiology and Biostatistics, MRC Health Protection Agency (PHE) Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.
Das S; Department of Epidemiology and Biostatistics, MRC Health Protection Agency (PHE) Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.
Dorajoo R; Genome Institute of Singapore, ASTAR, Singapore.
Hopewell JC; Clinical Trials Support Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Kim YK; Center for Genome Science, National Institute of Health, Osong Health Technology Administration Complex, Chungcheongbuk-do, Republic of Korea.
Koivula RW; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Skåne University Hospital Malmö, Malmö, Sweden.
Luan J; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, UK.
Lyytikäinen LP; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Department of Clinical Chemistry, University of Tampere School of Medicine, Tampere, Finland.
Nguyen QN; Vietnam National Heart Institute, Bach Mai Hospital, Hanoi, Vietnam.
Pereira MA; School of Public Health, University of Minnesota, Minneapolis, Minnesota, USA.
Postmus I; Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, the Netherlands.; Netherlands Consortium for Healthy Ageing, Leiden, the Netherlands.
Raitakari OT; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland.; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland.
Scannell Bryan M; Department of Public Health Sciences, University of Chicago, Chicago, Illinois, USA.
Scott RA; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, UK.
Sorice R; Institute of Genetics and Biophysics A Buzzati-Traverso, CNR, Naples, Italy.
Tragante V; Division of Heart and Lungs, Department of Cardiology, University Medical Center Utrecht, Utrecht, the Netherlands.
Traglia M; Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milan, Italy.; Institute for Maternal and Child Health, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) 'Burlo Garofolo', Trieste, Italy.
White J; University College London Genetics Institute, Department of Genetics, Environment and Evolution, University College London, London, UK.
Yamamoto K; Division of Genomics, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.
Zhang Y; Department of Epidemiology, School of Public Health, Medical College of Soochow University, Suzhou, China.
Adair LS; Department of Nutrition, University of North Carolina, Chapel Hill, North Carolina, USA.
Ahmed A; UChicago Research Bangladesh, Uttara, Dhaka, Bangladesh.
Akiyama K; Department of Gene Diagnostics and Therapeutics, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan.
Asif R; Center for Non-Communicable Diseases, Karachi, Pakistan.
Aung T; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.
Barroso I; Metabolic Disease Group, Wellcome Trust Sanger Institute, Cambridge, UK.; National Institute for Health Research (NIHR) Cambridge Biomedical Research Centre, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK.; University of Cambridge Metabolic Research Laboratories, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK.
Bjonnes A; Center for Human Genetic Research, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Braun TR; Department of Pediatrics, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA.
Cai H; Vanderbilt Epidemiology Center, Division of Epidemiology, Department of Medicine, Vanderbilt Genetics Institute, Vanderbilt University, Nashville, Tennessee, USA.; Vanderbilt-Ingram Cancer Center, Division of Epidemiology, Department of Medicine, Vanderbilt University, Nashville, Tennessee, USA.
Chang LC; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.
Chen CH; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.; School of Chinese Medicine, China Medical University, Taichung, Taiwan.
Cheng CY; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore.; Department of Ophthalmology, National University of Singapore, Singapore.; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.; Centre for Quantitative Medicine, Office of Clinical Sciences, Duke-National University of Singapore Graduate Medical School, Singapore.
Chong YS; Singapore Institute for Clinical Sciences (SICS), ASTAR, Singapore.; Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Collins R; Clinical Trials Support Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Courtney R; Vanderbilt Epidemiology Center, Division of Epidemiology, Department of Medicine, Vanderbilt Genetics Institute, Vanderbilt University, Nashville, Tennessee, USA.; Vanderbilt-Ingram Cancer Center, Division of Epidemiology, Department of Medicine, Vanderbilt University, Nashville, Tennessee, USA.
Davies G; Centre for Cognitive Aging and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Department of Psychology, University of Edinburgh, Edinburgh, UK.
Delgado G; Medical Clinic V, Mannheim Medical Faculty, University of Heidelberg, Mannheim, Germany.
Do LD; Vietnam National Heart Institute, Bach Mai Hospital, Hanoi, Vietnam.
Doevendans PA; Division of Heart and Lungs, Department of Cardiology, University Medical Center Utrecht, Utrecht, the Netherlands.
Gansevoort RT; Department of Internal Medicine, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
Gao YT; Department of Epidemiology, Shanghai Cancer Institute, Shanghai, China.
Grammer TB; Medical Clinic V, Mannheim Medical Faculty, University of Heidelberg, Mannheim, Germany.
Grarup N; Novo Nordisk Foundation Centre for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Grewal J; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Ealing Hospital National Health Service (NHS) Trust, Middlesex, UK.
Gu D; Fu Wai Hospital and Cardiovascular Institute, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Wander GS; Dayanand Medical College and Hospital Unit, Hero DMC Heart Institute, Ludhiana, India.
Hartikainen AL; Department of Obstetrics and Gynecology, Oulu University Hospital, Oulu, Finland.; Medical Research Center, University of Oulu, Oulu, Finland.; Unit of Primary Care, Oulu University Hospital, Oulu, Finland.
Hazen SL; Department of Cardiovascular Medicine, Heart and Vascular Institute, Cleveland Clinic, Cleveland, Ohio, USA.; Department of Cell Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, USA.
He J; Department of Biostatistics, Vanderbilt University, Nashville, Tennessee, USA.
Heng CK; Department of Paediatrics, Yong Loo Lin School of Medicine, Singapore.
Hixson JE; Human Genetics Center, University of Texas School of Public Health at Houston, Houston, Texas, USA.
Hofman A; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands.
Hsu C; University of Southern California Keck School of Medicine, Los Angeles, California, USA.
Huang W; Department of Genetics, Chinese National Human Genomic Center, Shanghai, China.
Husemoen LLN; Research Centre for Prevention and Health, Glostrup University Hospital, Glostrup, Denmark.
Hwang JY; Center for Genome Science, National Institute of Health, Osong Health Technology Administration Complex, Chungcheongbuk-do, Republic of Korea.
Ichihara S; Graduate School of Regional Innovation Studies, Mie University, Tsu, Japan.
Igase M; Department of Geriatric Medicine, Ehime University Graduate School of Medicine, Toon, Ehime, Japan.
Isono M; Department of Gene Diagnostics and Therapeutics, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan.
Justesen JM; Novo Nordisk Foundation Centre for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Katsuya T; Department of Clinical Gene Therapy, Osaka University Graduate School of Medicine, Suita, Japan.; Department of Geriatric Medicine and Nephrology, Osaka University Graduate School of Medicine, Suita, Japan.
Kibriya MG; Department of Public Health Sciences, University of Chicago, Chicago, Illinois, USA.
Kim YJ; Center for Genome Science, National Institute of Health, Osong Health Technology Administration Complex, Chungcheongbuk-do, Republic of Korea.
Kishimoto M; National Center for Global Health and Medicine, Toyama, Japan.
Koh WP; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore.; Duke-National University of Singapore Graduate Medical School, Singapore.
Kohara K; Department of Geriatric Medicine, Ehime University Graduate School of Medicine, Toon, Ehime, Japan.
Kumari M; Department of Epidemiology and Public Health, University College London, London, UK.
Kwek K; K.K. Women's and Children's Hospital, Singapore.
Lee NR; University of San Carlos Office of Population Studies Foundation, University of San Carlos, Cebu City, Philippines.; Department of Anthropology, Sociology and History, University of San Carlos, Cebu City, Philippines.
Lee J; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore.
Liao J; Department of Ophthalmology, National University of Singapore, Singapore.; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.
Lieb W; Institute of Epidemiology and Biobank popgen, Christian Albrechts University of Kiel, Kiel, Germany.
Liewald DCM; Centre for Cognitive Aging and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Department of Psychology, University of Edinburgh, Edinburgh, UK.
Matsubara T; Department of Internal Medicine, Aichi-Gakuin University School of Dentistry, Nagoya, Japan.
Matsushita Y; National Center for Global Health and Medicine, Toyama, Japan.
Meitinger T; Institute of Human Genetics, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Human Genetics, Technische Universität München, Munich, Germany.
Mihailov E; Estonian Genome Center, University of Tartu, Tartu, Estonia.
Milani L; Estonian Genome Center, University of Tartu, Tartu, Estonia.
Mills R; Ealing Hospital National Health Service (NHS) Trust, Middlesex, UK.
Mononen N; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Department of Clinical Chemistry, University of Tampere School of Medicine, Tampere, Finland.
Müller-Nurasyid M; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Department of Medicine I, Ludwig Maximilians University Munich, Munich, Germany.; German Center for Cardiovascular Research (DZHK), partner site Munich Heart Alliance, Munich, Germany.
Nabika T; Department of Functional Pathology, Shimane University Faculty of Medicine, Izumo, Japan.
Nakashima E; Division of Endocrinology and Diabetes, Department of Internal Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan.; Department of Diabetes and Endocrinology, Chubu Rosai Hospital, Nagoya, Japan.
Ng HK; Cancer Science Institute of Singapore, National University of Singapore, Singapore.
Nikus K; Heart Centre, Department of Cardiology, Tampere University Hospital and University of Tampere School of Medicine, Tampere, Finland.
Nutile T; Institute of Genetics and Biophysics A Buzzati-Traverso, CNR, Naples, Italy.
Ohkubo T; Department of Hygiene and Public Health, Teikyo University School of Medicine, Tokyo, Japan.
Ohnaka K; Department of Geriatric Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Parish S; Clinical Trials Support Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Paternoster L; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.
Peng H; Department of Epidemiology, School of Public Health, Medical College of Soochow University, Suzhou, China.
Peters A; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; German Center for Cardiovascular Research (DZHK), partner site Munich Heart Alliance, Munich, Germany.
Pham ST; Vietnam National Heart Institute, Bach Mai Hospital, Hanoi, Vietnam.
Pinidiyapathirage MJ; Department of Public Health, Faculty of Medicine, University of Kelaniya, Ragama, Sri Lanka.
Rahman M; UChicago Research Bangladesh, Uttara, Dhaka, Bangladesh.; Research and Evaluation Division, Bangladesh Rehabilitation Assistance Committee (BRAC), Dhaka, Bangladesh.
Rakugi H; Department of Geriatric Medicine and Nephrology, Osaka University Graduate School of Medicine, Suita, Japan.
Rolandsson O; Department of Public Health and Clinical Medicine, Section for Family Medicine, Umeå Universitet, Umeå, Sweden.
Ann Rozario M; Cancer Science Institute of Singapore, National University of Singapore, Singapore.
Ruggiero D; Institute of Genetics and Biophysics A Buzzati-Traverso, CNR, Naples, Italy.
Sala CF; Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milan, Italy.
Sarju R; Dayanand Medical College and Hospital Unit, Hero DMC Heart Institute, Ludhiana, India.
Shimokawa K; Department of Gene Diagnostics and Therapeutics, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan.
Snieder H; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
Sparsø T; Novo Nordisk Foundation Centre for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Spiering W; Department of Vascular Medicine, University Medical Center Utrecht, Utrecht, the Netherlands.
Starr JM; Centre for Cognitive Aging and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Alzheimer Scotland Dementia Research Centre, University of Edinburgh, Edinburgh, UK.
Stott DJ; Academic Section of Geriatric Medicine, Institute of Cardiovascular and Medical Sciences, Faculty of Medicine, University of Glasgow, Glasgow, UK.
Stram DO; University of Southern California Keck School of Medicine, Los Angeles, California, USA.
Sugiyama T; Institute for Adult Diseases, Asahi Life Foundation, Tokyo, Japan.
Szymczak S; Institute of Clinical Molecular Biology, Christian Albrechts University of Kiel, Kiel, Germany.
Tang WHW; Department of Cardiovascular Medicine, Heart and Vascular Institute, Cleveland Clinic, Cleveland, Ohio, USA.; Department of Cellular and Molecular Medicine, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Tong L; Department of Public Health Sciences, University of Chicago, Chicago, Illinois, USA.
Trompet S; Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands.
Turjanmaa V; Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland.; Department of Clinical Physiology, University of Tampere School of Medicine, Tampere, Finland.
Ueshima H; Department of Health Science, Shiga University of Medical Science, Otsu, Japan.; Center for Epidemiologic Research in Asia, Shiga University of Medical Science, Otsu, Japan.
Uitterlinden AG; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands.; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands.
Umemura S; Department of Medical Science and Cardiorenal Medicine, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Vaarasmaki M; Department of Obstetrics and Gynecology, Oulu University Hospital, Oulu, Finland.; Medical Research Center, University of Oulu, Oulu, Finland.; Unit of Primary Care, Oulu University Hospital, Oulu, Finland.
van Dam RM; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore.
van Gilst WH; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
van Veldhuisen DJ; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
Viikari JS; Division of Medicine, Turku University Hospital, Turku, Finland.; Department of Medicine, University of Turku, Turku, Finland.
Waldenberger M; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.
Wang Y; Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China.
Wang A; Department of Epidemiology, School of Public Health, Medical College of Soochow University, Suzhou, China.
Wilson R; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.
Wong TY; Department of Ophthalmology, National University of Singapore, Singapore.; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.
Xiang YB; Department of Epidemiology, Shanghai Cancer Institute, Shanghai, China.
Yamaguchi S; Third Department of Internal Medicine, Shimane University Faculty of Medicine, Izumo, Japan.
Ye X; Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China.
Young RD; Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory, Cambridge, UK.
Young TL; Neuroscience and Behavioural Disorders (NBD) Program, Duke-National University of Singapore Graduate Medical School, Singapore.; Duke Eye Center, Duke University Medical Center, Durham, North Carolina, USA.
Yuan JM; Cancer Control and Population Sciences, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania, USA.
Zhou X; Bioinformatics Division, Tsinghua National Laboratory for Informatics Science and Technology (TNLIST), Ministry of Education Key Laboratory of Bioinformatics, Department of Automation, Tsinghua University, Beijing, China.; Center for Synthetic and Systems Biology, TNLIST, Ministry of Education Key Laboratory of Bioinformatics, Department of Automation, Tsinghua University, Beijing, China.; Department of Psychiatry, University of Hong Kong, Hong Kong.
Asselbergs FW; Division of Heart and Lungs, Department of Cardiology, University Medical Center Utrecht, Utrecht, the Netherlands.; Durrer Center for Cardiogenetic Research, Interuniversity Cardiology Institute of the Netherlands (ICIN)-Netherlands Heart Institute, Utrecht, the Netherlands.; Institute of Cardiovascular Science, Faculty of Population Health Sciences, University College London, London, UK.
Ciullo M; Institute of Genetics and Biophysics A Buzzati-Traverso, CNR, Naples, Italy.
Clarke R; Clinical Trials Support Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Deloukas P; William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; King Abdulaziz University, Jeddah, Saudi Arabia.
Franke A; Institute of Clinical Molecular Biology, Christian Albrechts University of Kiel, Kiel, Germany.
Franks PW; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Skåne University Hospital Malmö, Malmö, Sweden.; Department of Public Health and Clinical Medicine, Section for Family Medicine, Umeå Universitet, Umeå, Sweden.; Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA.
Franks S; Institute of Reproductive and Developmental Biology, Imperial College London, Hammersmith Hospital, London, UK.
Friedlander Y; Hebrew University, School of Public Health, Jerusalem, Israel.
Gross MD; School of Medicine, University of Minnesota, Minneapolis, Minnesota, USA.
Guo Z; Department of Epidemiology, School of Public Health, Medical College of Soochow University, Suzhou, China.
Hansen T; Novo Nordisk Foundation Centre for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Jarvelin MR; Institute of Health Sciences, University of Oulu, Oulu, Finland.; Department of Epidemiology and Biostatistics, MRC Health Protection Agency (PHE) Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.; Unit of Primary Care, Oulu University Hospital, Oulu, Finland.; Biocenter Oulu, University of Oulu, Oulu, Finland.; Center for Life Course Epidemiology, Faculty of Medicine, University of Oulu, Oulu, Finland.
Jørgensen T; Research Centre for Prevention and Health, Glostrup University Hospital, Glostrup, Denmark.
Jukema JW; Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands.; Durrer Center for Cardiogenetic Research, Interuniversity Cardiology Institute of the Netherlands (ICIN)-Netherlands Heart Institute, Utrecht, the Netherlands.; ICIN, Utrecht, the Netherlands.
Kähönen M; Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland.; Department of Clinical Physiology, University of Tampere School of Medicine, Tampere, Finland.
Kajio H; National Center for Global Health and Medicine, Toyama, Japan.
Kivimaki M; Department of Epidemiology and Public Health, University College London, London, UK.
Lee JY; Ministry of Health and Welfare, Seoul, Republic of Korea.; THERAGEN ETEX Bio Institute, Suwon, Republic of Korea.
Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Department of Clinical Chemistry, University of Tampere School of Medicine, Tampere, Finland.
Linneberg A; Research Centre for Prevention and Health, Glostrup University Hospital, Glostrup, Denmark.; Department of Clinical Experimental Research, Rigshospitalet, Copenhagen, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Miki T; Department of Geriatric Medicine, Ehime University Graduate School of Medicine, Toon, Ehime, Japan.
Pedersen O; Novo Nordisk Foundation Centre for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Samani NJ; Department of Cardiovascular Sciences, University of Leicester, Glenfield Hospital, Leicester, UK.; NIHR Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, Leicester, UK.
Sørensen TIA; Novo Nordisk Foundation Centre for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Institute of Preventive Medicine, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark.
Takayanagi R; Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Kyushu, Japan.
Toniolo D; Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milan, Italy.; Institute of Molecular Genetics, National Research Council (CNR), Pavia, Italy.
Ahsan H; Department of Public Health Sciences, University of Chicago, Chicago, Illinois, USA.
Allayee H; Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, California, USA.; Institute for Genetic Medicine, University of Southern California Keck School of Medicine, Los Angeles, California, USA.
Chen YT; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.
Danesh J; Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory, Cambridge, UK.; Wellcome Trust Sanger Institute, Hinxton, UK.
Deary IJ; Centre for Cognitive Aging and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Department of Psychology, University of Edinburgh, Edinburgh, UK.
Franco OH; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands.
Franke L; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
Heijman BT; Molecular Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.
Holbrook JD; Singapore Institute for Clinical Sciences (SICS), ASTAR, Singapore.
Isaacs A; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands.
Kim BJ; Center for Genome Science, National Institute of Health, Osong Health Technology Administration Complex, Chungcheongbuk-do, Republic of Korea.
Lin X; Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China.
Liu J; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore.; Genome Institute of Singapore, ASTAR, Singapore.
März W; Medical Clinic V, Mannheim Medical Faculty, University of Heidelberg, Mannheim, Germany.; Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria.; Synlab Academy, Synlab Services, Mannheim, Germany.
Metspalu A; Estonian Genome Center, University of Tartu, Tartu, Estonia.
Mohlke KL; Department of Genetics, University of North Carolina, Chapel Hill, North Carolina, USA.
Sanghera DK; Department of Pediatrics, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA.
Shu XO; Vanderbilt Epidemiology Center, Division of Epidemiology, Department of Medicine, Vanderbilt Genetics Institute, Vanderbilt University, Nashville, Tennessee, USA.; Vanderbilt-Ingram Cancer Center, Division of Epidemiology, Department of Medicine, Vanderbilt University, Nashville, Tennessee, USA.
van Meurs JBJ; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands.
Vithana E; Department of Ophthalmology, National University of Singapore, Singapore.; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.; Neuroscience and Behavioural Disorders (NBD) Program, Duke-National University of Singapore Graduate Medical School, Singapore.
Wickremasinghe AR; Department of Public Health, Faculty of Medicine, University of Kelaniya, Ragama, Sri Lanka.
Wijmenga C; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
Wolffenbuttel BHW; Department of Endocrinology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
Yokota M; Department of Genome Science, Aichi-Gakuin University School of Dentistry, Nagoya, Japan.
Zheng W; Vanderbilt Epidemiology Center, Division of Epidemiology, Department of Medicine, Vanderbilt Genetics Institute, Vanderbilt University, Nashville, Tennessee, USA.; Vanderbilt-Ingram Cancer Center, Division of Epidemiology, Department of Medicine, Vanderbilt University, Nashville, Tennessee, USA.
Zhu D; State Key Laboratory of Medical Genetics, Shanghai Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai Institute of Hypertension, Shanghai, China.
Vineis P; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.
Kyrtopoulos SA; National Hellenic Research Foundation, Institute of Biology, Medicinal Chemistry and Biotechnology, Athens, Greece.
Kleinjans JCS; Department of Toxicogenomics, Maastricht University, Maastricht, the Netherlands.
McCarthy MI; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Oxford Centre for Diabetes Endocrinology and Metabolism, University of Oxford, Oxford, UK.
Soong R; Cancer Science Institute of Singapore, National University of Singapore, Singapore.; Department of Pathology, National University of Singapore, Singapore.
Gieger C; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.
Scott J; National Heart and Lung Institute, Imperial College London, London, UK.
Teo YY; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore.; Genome Institute of Singapore, ASTAR, Singapore.; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.; National University of Singapore Graduate School for Integrative Science and Engineering, National University of Singapore, Singapore.; Life Sciences Institute, National University of Singapore, Singapore.; Department of Statistics and Applied Probability, National University of Singapore, Singapore.
He J; Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana, USA.
Elliott P; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.
Tai ES; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore.; Department of Clinical Gene Therapy, Osaka University Graduate School of Medicine, Suita, Japan.; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
van der Harst P; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.; Durrer Center for Cardiogenetic Research, Interuniversity Cardiology Institute of the Netherlands (ICIN)-Netherlands Heart Institute, Utrecht, the Netherlands.
Kooner JS; Ealing Hospital National Health Service (NHS) Trust, Middlesex, UK.; National Heart and Lung Institute, Imperial College London, London, UK.; Imperial College Healthcare NHS Trust, London, UK.
Chambers JC; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Ealing Hospital National Health Service (NHS) Trust, Middlesex, UK.; Imperial College Healthcare NHS Trust, London, UK.; Pokaż więcej
Corporate Authors:: BIOS-consortium
CARDIo GRAMplusCD
LifeLines Cohort Study
InterAct Consortium
Źródło:: Nature genetics [Nat Genet] 2015 Nov; Vol. 47 (11), pp. 1282-1293. Date of Electronic Publication: 2015 Sep 21.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:: DNA Methylation*
Blood Pressure/*genetics
Genetic Loci/*genetics
Genome-Wide Association Study/*methods
Adult ; Aged ; Aged, 80 and over ; Asian People/genetics ; Cardiovascular Diseases/blood ; Cardiovascular Diseases/ethnology ; Cardiovascular Diseases/genetics ; Female ; Genetic Predisposition to Disease/ethnology ; Genetic Predisposition to Disease/genetics ; Genetic Variation ; Genotype ; Humans ; Male ; Middle Aged ; Natriuretic Peptide, Brain/blood ; Peptide Fragments/blood ; Polymorphism, Single Nucleotide ; Regression Analysis ; Risk Factors ; White People/genetics

Czasopismo naukowe

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Pełny tekst Szczegóły

Skocz do pozycji: 4.

Tytuł:: Genome-wide analysis of multi-ancestry cohorts identifies new loci influencing intraocular pressure and susceptibility to glaucoma.
Autorzy:: Hysi PG; Department of Twin Research and Genetic Epidemiology, King's College London, UK.
Cheng CY; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.; Department of Ophthalmology, National University of Singapore and National University Health System, Singapore.; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore.; Duke-National University of Singapore, Graduate Medical School, Singapore.
Springelkamp H; Department of Ophthalmology, Erasmus Medical Center, Rotterdam, the Netherlands.; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.
Macgregor S; Statistical Genetics, QIMR Berghofer Medical Research Institute Royal Brisbane Hospital, Brisbane, Australia 4029.
Bailey JNC; Department of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, OH, USA.
Wojciechowski R; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health and, Baltimore, MD, USA.; National Human Genome Research Institute, National Institutes of Health, Baltimore, MD 21224, USA.
Vitart V; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh.
Nag A; Department of Twin Research and Genetic Epidemiology, King's College London, UK.
Hewitt AW; Centre for Eye Research Australia, University of Melbourne, Royal Victorian Eye and Ear Hospital, Australia.
Höhn R; Department of Ophthalmology, University Medical Center Mainz, Mainz, Germany.
Venturini C; Department of Twin Research and Genetic Epidemiology, King's College London, UK.; Institute of Ophthalmology, University College London, UK.
Mirshahi A; Department of Ophthalmology, University Medical Center Mainz, Mainz, Germany.
Ramdas WD; Department of Ophthalmology, Erasmus Medical Center, Rotterdam, the Netherlands.; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.
Thorleifsson G; deCODE/Amgen, 101 Reykjavik, Iceland.
Vithana E; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.; Department of Ophthalmology, National University of Singapore and National University Health System, Singapore.; Duke-National University of Singapore, Graduate Medical School, Singapore.
Khor CC; Department of Ophthalmology, National University of Singapore and National University Health System, Singapore.; Division of Human Genetics, Genome Institute of Singapore, Singapore.
Stefansson AB; Eye Clinic, 105 Reykjavik, Iceland.
Liao J; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.; Department of Ophthalmology, National University of Singapore and National University Health System, Singapore.
Haines JL; Department of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, OH, USA.
Amin N; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.
Wang YX; Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital University of Medical Science, Beijing, China 100730.
Wild PS; Department of Internal Medicine II, University Medical Center Mainz, Mainz, Germany.
Ozel AB; Department of Human Genetics, University of Michigan, Ann Arbor, MI, USA.
Li JZ; Department of Human Genetics, University of Michigan, Ann Arbor, MI, USA.
Fleck BW; NHS Princess Alexandra Eye Pavilion, Edinburgh, UK.
Zeller T; Clinic for General and Interventional Cardiology, University Heart Center Hamburg, Germany.
Staffieri SE; Centre for Eye Research Australia, University of Melbourne, Royal Victorian Eye and Ear Hospital, Australia.
Teo YY; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore.; Department of Statistics and Applied Probability, National University of Singapore, Singapore.
Cuellar-Partida G; Statistical Genetics, QIMR Berghofer Medical Research Institute Royal Brisbane Hospital, Brisbane, Australia 4029.
Luo X; Duke University, Duke Eye Center, Durham, NC, USA.
Allingham RR; Department of Ophthalmology, Duke University Medical Center, Durham, NC, USA.
Richards JE; Department of Ophthalmology, Erasmus Medical Center, Rotterdam, the Netherlands.
Senft A; Institute of Medical Biometry and Statistics, University Hospital Schleswig-Holstein, Lübeck, Germany.
Karssen LC; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.
Zheng Y; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore.
Bellenguez C; Inserm, UMR774, Lille, France.; Université Lille 2, Lille, France.; Institut Pasteur de Lille, France.
Xu L; Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital University of Medical Science, Beijing, China 100730.
Iglesias AI; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.
Wilson JF; Centre for Population Health Sciences, University of Edinburgh Medical School, Edinburgh, UK.
Kang JH; Channing Division of Network Medicine, Harvard Medical School, Boston, MA, USA.
van Leeuwen EM; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.
Jonsson V; Department of Ophthalmology, Landspitali National University Hospital, Reykjavik, Iceland.
Thorsteinsdottir U; deCODE/Amgen, 101 Reykjavik, Iceland.
Despriet DDG; Department of Ophthalmology, Erasmus Medical Center, Rotterdam, the Netherlands.
Ennis S; Human Genetics & Genomic Medicine, Faulty of Medicine, University of Southampton, UK.
Moroi SE; Department of Ophthalmology and Visual Sciences, University of Michigan, Ann Arbor, MI, USA.
Martin NG; Genetic Epidemiology, QIMR Berghofer Medical Research Institute Royal Brisbane Hospital, Brisbane, Australia.
Jansonius NM; Department of Ophthalmology, University Medical Center Groningen, the Netherlands.
Yazar S; Centre for Ophthalmology and Visual Science, Lions Eye Institute, University of Western Australia, Perth, Australia.
Tai ES; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore.; Duke-National University of Singapore, Graduate Medical School, Singapore.; Department of Medicine, National University of Singapore and National University Health System, Singapore.
Amouyel P; Institute of Medical Biometry and Statistics, University Hospital Schleswig-Holstein, Lübeck, Germany.; Inserm, UMR774, Lille, France.; Université Lille 2, Lille, France.; Centre Hospitalier Régional Universitaire de Lille, France.
Kirwan J; Department of Ophthalmology, Portsmouth Hospitals NHS Trust, Portsmouth, UK.
van Koolwijk LME; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.
Hauser MA; Department of Ophthalmology, Duke University Medical Center, Durham, NC, USA.; Department of Medicine, Duke University Medical Center, Durham, NC, USA.
Jonasson F; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.
Leo P; The University of Queensland, Diamantina Institute, Woollongabba, Australia.
Loomis SJ; Dept. Ophthalmology Harvard Medical School and Massachusetts Eye and Ear Infirmary, Boston, MA, USA.
Fogarty R; Department of Ophthalmology, Flinders University, Adelaide, Australia.
Rivadeneira F; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, the Netherlands.; Netherlands Consortium for Healthy Ageing, Netherlands Genomics Initiative, The Hague, the Netherlands.
Kearns L; Centre for Eye Research Australia, University of Melbourne, Royal Victorian Eye and Ear Hospital, Australia.
Lackner KJ; Institute of Clinical Chemistry and Laboratory Medicine, Mainz, Germany.
de Jong PTVM; Netherlands Institute for Neuroscience, Amsterdam, the Netherlands.; Department of Ophthalmology, Leiden University Medical Center, Leiden, the Netherlands.; Department of Ophthalmology, Academic Medical Center, Amsterdam, the Netherlands.
Simpson CL; National Human Genome Research Institute, National Institutes of Health, Baltimore, MD 21224, USA.
Pennell CE; School of Women's and Infants' Health, The University of Western Australia, Perth, Australia.
Oostra BA; Department of Clinical Genetics, Erasmus Medical Center, Rotterdam, the Netherlands.
Uitterlinden AG; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, the Netherlands.; Netherlands Consortium for Healthy Ageing, Netherlands Genomics Initiative, The Hague, the Netherlands.
Saw SM; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.; Department of Ophthalmology, National University of Singapore and National University Health System, Singapore.; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore.; Duke-National University of Singapore, Graduate Medical School, Singapore.
Lotery AJ; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, UK.
Bailey-Wilson JE; National Human Genome Research Institute, National Institutes of Health, Baltimore, MD 21224, USA.
Hofman A; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.; Netherlands Consortium for Healthy Ageing, Netherlands Genomics Initiative, The Hague, the Netherlands.
Vingerling JR; Department of Ophthalmology, Erasmus Medical Center, Rotterdam, the Netherlands.; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.
Maubaret C; Univ. Bordeaux, ISPED, Bordeaux, France.; Inserm, Centre INSERM U897-Epidemiologie-Biostatistique Bordeaux, France.
Pfeiffer N; Department of Ophthalmology, University Medical Center Mainz, Mainz, Germany.
Wolfs RCW; Department of Ophthalmology, Erasmus Medical Center, Rotterdam, the Netherlands.
Lemij HG; Glaucoma Service, the Rotterdam Eye Hospital, Rotterdam, the Netherlands.
Young TL; Duke University, Duke Eye Center, Durham, NC, USA.
Pasquale LR; Channing Division of Network Medicine, Harvard Medical School, Boston, MA, USA.; Dept. Ophthalmology Harvard Medical School and Massachusetts Eye and Ear Infirmary, Boston, MA, USA.
Delcourt C; Univ. Bordeaux, ISPED, Bordeaux, France.; Inserm, Centre INSERM U897-Epidemiologie-Biostatistique Bordeaux, France.
Spector TD; Department of Twin Research and Genetic Epidemiology, King's College London, UK.
Klaver CCW; Department of Ophthalmology, Erasmus Medical Center, Rotterdam, the Netherlands.; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.
Small KS; Department of Twin Research and Genetic Epidemiology, King's College London, UK.
Burdon KP; Department of Ophthalmology, Flinders University, Adelaide, Australia.
Stefansson K; deCODE/Amgen, 101 Reykjavik, Iceland.
Wong TY; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.; Department of Ophthalmology, National University of Singapore and National University Health System, Singapore.; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore.
Viswanathan A; NIHR Biomedical Research Centre, Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, UK.
Mackey DA; Centre for Eye Research Australia, University of Melbourne, Royal Victorian Eye and Ear Hospital, Australia.; Centre for Ophthalmology and Visual Science, Lions Eye Institute, University of Western Australia, Perth, Australia.
Craig JE; Department of Ophthalmology, Flinders University, Adelaide, Australia.
Wiggs JL; Dept. Ophthalmology Harvard Medical School and Massachusetts Eye and Ear Infirmary, Boston, MA, USA.
van Duijn CM; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.
Hammond CJ; Department of Twin Research and Genetic Epidemiology, King's College London, UK.
Aung T; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.; Department of Ophthalmology, National University of Singapore and National University Health System, Singapore.; Pokaż więcej
Corporate Authors:: BMES GWAS Group
NEIGHBORHOOD Consortium
Wellcome Trust Case Control Consortium 2
Źródło:: Nature genetics [Nat Genet] 2014 Oct; Vol. 46 (10), pp. 1126-1130. Date of Electronic Publication: 2014 Aug 31.
Typ publikacji:: Journal Article
MeSH Terms:: Genome-Wide Association Study*
Genetic Loci/*genetics
Genetic Predisposition to Disease/*genetics
Glaucoma/*genetics
Intraocular Pressure/*genetics
ABO Blood-Group System/genetics ; ATP Binding Cassette Transporter 1/genetics ; Adult ; Aged ; Aged, 80 and over ; Chromosomes, Human, Pair 11/genetics ; Chromosomes, Human, Pair 3/genetics ; Chromosomes, Human, Pair 9/genetics ; Cohort Studies ; Female ; Fibronectins/genetics ; Genotype ; Glaucoma, Open-Angle/genetics ; Humans ; Male ; Meta-Analysis as Topic ; Middle Aged ; Polymorphism, Single Nucleotide ; Risk Factors ; Young Adult

Czasopismo naukowe

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Pełny tekst Szczegóły

Skocz do pozycji: 5.

Tytuł:: ABCC5, a gene that influences the anterior chamber depth, is associated with primary angle closure glaucoma.
Autorzy:: Nongpiur ME; Singapore Eye Research Institute and Singapore National Eye Centre, Singapore.
Khor CC; Singapore Eye Research Institute and Singapore National Eye Centre, Singapore; Infectious Diseases, Genome Institute of Singapore, Singapore; Human Genetics, Genome Institute of Singapore, Singapore; Department of Paediatrics, National University Health System & National University of Singapore, Singapore; Saw Swee Hock School of Public Health, National University of Singapore, Singapore.
Jia H; Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology & Visual Sciences Key Lab, Beijing, China.
Cornes BK; Singapore Eye Research Institute and Singapore National Eye Centre, Singapore.
Chen LJ; Department of Ophthalmology & Visual Sciences, the Chinese University of Hong Kong, Hong Kong, China.
Qiao C; Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology & Visual Sciences Key Lab, Beijing, China.
Nair KS; Howard Hughes Medical Institute, The Jackson Laboratory, Bar Harbor, Maine, United States of America.
Cheng CY; Singapore Eye Research Institute and Singapore National Eye Centre, Singapore; Saw Swee Hock School of Public Health, National University of Singapore, Singapore; Department of Ophthalmology, National University Health System & National University of Singapore, Singapore.
Xu L; Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital University of Medical Science, Beijing, China.
George R; Vision Research Foundation, Sankara Nethralaya, Chennai, India.
Tan D; Vietnam National Institute of Ophthalmology, Hanoi, Vietnam.
Abu-Amero K; Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Perera SA; Singapore Eye Research Institute and Singapore National Eye Centre, Singapore.
Ozaki M; Ozaki Eye Hospital, Hyuga, Japan.
Mizoguchi T; Mizoguchi Eye Clinic, Sasebo, Japan.
Kurimoto Y; Kobe Gen Hospital, Kobe, Japan.
Low S; NIHR Biomedical Research Centre for Ophthalmology at Moorfields Eye Hospital and UCL Institute of Ophthalmology, London, United Kingdom.
Tajudin LS; Department of Ophthalmology, School of Medical Sciences, Universiti Sains Malaysia, Kota Bharu, Kelantan, Malaysia.
Ho CL; Singapore Eye Research Institute and Singapore National Eye Centre, Singapore.
Tham CC; Department of Ophthalmology & Visual Sciences, the Chinese University of Hong Kong, Hong Kong, China.
Soto I; Howard Hughes Medical Institute, The Jackson Laboratory, Bar Harbor, Maine, United States of America.
Chew PT; Department of Ophthalmology, National University Health System & National University of Singapore, Singapore.
Wong HT; Department of Ophthalmology, Tan Tock Seng Hospital, Singapore.
Shantha B; Vision Research Foundation, Sankara Nethralaya, Chennai, India.
Kuroda M; Kobe Gen Hospital, Kobe, Japan.
Osman EA; Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Tang G; Xingtai Eye Hospital, Xingtai, China.
Fan S; Handan Eye Hospital, Handan, China.
Meng H; Anyang Eye Hospital, Anyang, China.
Wang H; Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology & Visual Sciences Key Lab, Beijing, China.
Feng B; Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology & Visual Sciences Key Lab, Beijing, China.
Yong VH; Singapore Eye Research Institute and Singapore National Eye Centre, Singapore.
Ting SM; Singapore Eye Research Institute and Singapore National Eye Centre, Singapore.
Li Y; Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital University of Medical Science, Beijing, China.
Wang YX; Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital University of Medical Science, Beijing, China.
Li Z; Singapore Eye Research Institute and Singapore National Eye Centre, Singapore.
Lavanya R; Singapore Eye Research Institute and Singapore National Eye Centre, Singapore.
Wu RY; Singapore Eye Research Institute and Singapore National Eye Centre, Singapore.
Zheng YF; Singapore Eye Research Institute and Singapore National Eye Centre, Singapore.
Su DH; Singapore Eye Research Institute and Singapore National Eye Centre, Singapore.
Loon SC; Department of Ophthalmology, National University Health System & National University of Singapore, Singapore.
Yong VK
Allingham RR; Duke University Medical Center, Durham, North Carolina, United States of America.
Hauser MA; Duke University Medical Center, Durham, North Carolina, United States of America.
Soumittra N; Vision Research Foundation, Sankara Nethralaya, Chennai, India.
Ramprasad VL; Vision Research Foundation, Sankara Nethralaya, Chennai, India.
Waseem N; NIHR Biomedical Research Centre for Ophthalmology at Moorfields Eye Hospital and UCL Institute of Ophthalmology, London, United Kingdom.
Yaakub A; Department of Ophthalmology, School of Medical Sciences, Universiti Sains Malaysia, Kota Bharu, Kelantan, Malaysia.
Chia KS; Department of Ophthalmology, National University Health System & National University of Singapore, Singapore.
Kumaramanickavel G; Vision Research Foundation, Sankara Nethralaya, Chennai, India.
Wong TT; Singapore Eye Research Institute and Singapore National Eye Centre, Singapore.
How AC; Singapore Eye Research Institute and Singapore National Eye Centre, Singapore.
Chau TN; Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.
Simmons CP; Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam; Centre for Tropical Medicine, Nuffield Department of Clinical Medicine, Oxford University, Oxford, United Kingdom.
Bei JX; State Key Laboratory of Oncology in Southern China, Guangzhou, China; Department of Experimental Research, Sun Yat-Sen University Cancer Centre, Guangzhou, China.
Zeng YX; State Key Laboratory of Oncology in Southern China, Guangzhou, China; Department of Experimental Research, Sun Yat-Sen University Cancer Centre, Guangzhou, China; Peking Union Medical College, Chinese Academy of Medical Science, Beijing, China.
Bhattacharya SS; NIHR Biomedical Research Centre for Ophthalmology at Moorfields Eye Hospital and UCL Institute of Ophthalmology, London, United Kingdom.
Zhang M; Shantou University/Chinese University of Hong Kong Joint Shantou International Eye Center, Shantou, China.
Tan DT; Singapore Eye Research Institute and Singapore National Eye Centre, Singapore; Department of Ophthalmology, National University Health System & National University of Singapore, Singapore.
Teo YY; Human Genetics, Genome Institute of Singapore, Singapore; Saw Swee Hock School of Public Health, National University of Singapore, Singapore.
Al-Obeidan SA; Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Hon DN; Vietnam National Institute of Ophthalmology, Hanoi, Vietnam.
Tai ES; Singapore Eye Research Institute and Singapore National Eye Centre, Singapore; Department of Medicine, National University Health System & National University of Singapore, Singapore.
Saw SM; Singapore Eye Research Institute and Singapore National Eye Centre, Singapore; Saw Swee Hock School of Public Health, National University of Singapore, Singapore.
Foster PJ; NIHR Biomedical Research Centre for Ophthalmology at Moorfields Eye Hospital and UCL Institute of Ophthalmology, London, United Kingdom.
Vijaya L; Vision Research Foundation, Sankara Nethralaya, Chennai, India.
Jonas JB; Department of Ophthalmology, Medical Faculty Mannheim of the Ruprecht-Karls-University Heidelberg, Germany.
Wong TY; Singapore Eye Research Institute and Singapore National Eye Centre, Singapore; Saw Swee Hock School of Public Health, National University of Singapore, Singapore; Department of Ophthalmology, National University Health System & National University of Singapore, Singapore.
John SW; Howard Hughes Medical Institute, The Jackson Laboratory, Bar Harbor, Maine, United States of America.
Pang CP; Department of Ophthalmology & Visual Sciences, the Chinese University of Hong Kong, Hong Kong, China.
Vithana EN; Singapore Eye Research Institute and Singapore National Eye Centre, Singapore; Department of Ophthalmology, National University Health System & National University of Singapore, Singapore.
Wang N; Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology & Visual Sciences Key Lab, Beijing, China; Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Aung T; Singapore Eye Research Institute and Singapore National Eye Centre, Singapore; Department of Ophthalmology, National University Health System & National University of Singapore, Singapore.; Pokaż więcej
Źródło:: PLoS genetics [PLoS Genet] 2014 Mar 06; Vol. 10 (3), pp. e1004089. Date of Electronic Publication: 2014 Mar 06 (Print Publication: 2014).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Genome-Wide Association Study*
Anterior Chamber/*pathology
Glaucoma, Angle-Closure/*genetics
Multidrug Resistance-Associated Proteins/*genetics
Anterior Chamber/metabolism ; Asian People ; Glaucoma, Angle-Closure/pathology ; Humans ; Polymorphism, Single Nucleotide ; Risk Factors

Czasopismo naukowe

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Pełny tekst Szczegóły

Skocz do pozycji: 6.

Tytuł:: Joint effects of known type 2 diabetes susceptibility loci in genome-wide association study of Singapore Chinese: the Singapore Chinese health study.
Autorzy:: Chen Z; Department of Preventive Medicine, University of Southern California, Los Angeles, California, United States of America.
Pereira MA; Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, Minnesota, United States of America.
Seielstad M; Department of Laboratory Medicine, Department of Epidemiology and Biostatistics, and California Institute for Quantitative Biosciences (QB3), University of California San Francisco, San Francisco, California, United States of America.
Koh WP; Duke-National University of Singapore Graduate Medical School, Singapore ; Saw Swee Hock School of Public Health, National University of Singapore, Singapore.
Tai ES; Duke-National University of Singapore Graduate Medical School, Singapore ; Saw Swee Hock School of Public Health, National University of Singapore, Singapore.
Teo YY; Saw Swee Hock School of Public Health, National University of Singapore, Singapore.
Liu J; Saw Swee Hock School of Public Health, National University of Singapore, Singapore ; Human Genetics, Genome Institute of Singapore, ASTAR, Singapore.
Hsu C; Department of Preventive Medicine, University of Southern California, Los Angeles, California, United States of America.
Wang R; Department of Epidemiology, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania, United States of America.
Odegaard AO; Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, Minnesota, United States of America.
Thyagarajan B; Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, Minnesota, United States of America.
Koratkar R; Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, Minnesota, United States of America.
Yuan JM; Department of Epidemiology, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania, United States of America.
Gross MD; Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, Minnesota, United States of America.
Stram DO; Department of Preventive Medicine, University of Southern California, Los Angeles, California, United States of America.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2014 Feb 10; Vol. 9 (2), pp. e87762. Date of Electronic Publication: 2014 Feb 10 (Print Publication: 2014).
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Genetic Predisposition to Disease*
Genome-Wide Association Study*
Asian People/*genetics
Diabetes Mellitus, Type 2/*genetics
Genetic Loci/*genetics
Aged ; Case-Control Studies ; Female ; Health ; Humans ; Male ; Middle Aged ; Polymorphism, Single Nucleotide ; Singapore

Czasopismo naukowe

na półce

Pełny tekst Szczegóły

Skocz do pozycji: 7.

Tytuł:: Pathways-driven sparse regression identifies pathways and genes associated with high-density lipoprotein cholesterol in two Asian cohorts.
Autorzy:: Silver M; Statistics Section, Department of Mathematics, Imperial College, London, United Kingdom ; MRC International Nutrition Group, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Chen P
Li R
Cheng CY
Wong TY
Tai ES
Teo YY
Montana G; Pokaż więcej
Źródło:: PLoS genetics [PLoS Genet] 2013 Nov; Vol. 9 (11), pp. e1003939. Date of Electronic Publication: 2013 Nov 21.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Genome-Wide Association Study*
Cholesterol/*genetics
Cholesterol, HDL/*genetics
Metabolic Networks and Pathways/*genetics
Asian People/genetics ; Calcium Channels, L-Type/genetics ; Genotype ; Humans ; Polymorphism, Single Nucleotide ; Receptors, Antigen, T-Cell/genetics

Czasopismo naukowe

na półce

Pełny tekst Szczegóły

Skocz do pozycji: 8.

Tytuł:: Are C-reactive protein associated genetic variants associated with serum levels and retinal markers of microvascular pathology in Asian populations from Singapore?
Autorzy:: Dorajoo R; Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore, Singapore.
Li R
Ikram MK
Liu J
Froguel P
Lee J
Sim X
Ong RT
Tay WT
Peng C
Young TL
Blakemore AI
Cheng CY
Aung T
Mitchell P
Wang JJ
Klaver CC
Boerwinkle E
Klein R
Siscovick DS
Jensen RA
Gudnason V
Smith AV
Teo YY
Wong TY
Tai ES
Heng CK
Friedlander Y; Pokaż więcej
Źródło:: PloS one [PLoS One] 2013 Jul 02; Vol. 8 (7), pp. e67650. Date of Electronic Publication: 2013 Jul 02 (Print Publication: 2013).
Typ publikacji:: Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't
MeSH Terms:: Asian People*
Genome-Wide Association Study*
C-Reactive Protein/*genetics
Microvessels/*metabolism
Retinal Artery/*metabolism
Retinal Vein/*metabolism
Adult ; Apolipoproteins E/genetics ; Cytokines/genetics ; Female ; Genetic Loci ; Hepatocyte Nuclear Factor 1-alpha/genetics ; Humans ; Linkage Disequilibrium ; Male ; Microvessels/pathology ; Middle Aged ; Polymorphism, Single Nucleotide ; Receptors, Leptin/genetics ; Retinal Artery/pathology ; Retinal Vein/pathology ; Singapore ; White People

Czasopismo naukowe

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Pełny tekst Szczegóły

Skocz do pozycji: 9.

Tytuł:: Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia.
Autorzy:: Verhoeven VJ; Department of Ophthalmology, Erasmus Medical Center, Rotterdam, The Netherlands.
Hysi PG
Wojciechowski R
Fan Q
Guggenheim JA
Höhn R
MacGregor S
Hewitt AW
Nag A
Cheng CY
Yonova-Doing E
Zhou X
Ikram MK
Buitendijk GH
McMahon G
Kemp JP
Pourcain BS
Simpson CL
Mäkelä KM
Lehtimäki T
Kähönen M
Paterson AD
Hosseini SM
Wong HS
Xu L
Jonas JB
Pärssinen O
Wedenoja J
Yip SP
Ho DW
Pang CP
Chen LJ
Burdon KP
Craig JE
Klein BE
Klein R
Haller T
Metspalu A
Khor CC
Tai ES
Aung T
Vithana E
Tay WT
Barathi VA
Chen P
Li R
Liao J
Zheng Y
Ong RT
Döring A
Evans DM
Timpson NJ
Verkerk AJ
Meitinger T
Raitakari O
Hawthorne F
Spector TD
Karssen LC
Pirastu M
Murgia F
Ang W
Mishra A
Montgomery GW
Pennell CE
Cumberland PM
Cotlarciuc I
Mitchell P
Wang JJ
Schache M
Janmahasatian S
Igo RP Jr
Lass JH
Chew E
Iyengar SK
Gorgels TG
Rudan I
Hayward C
Wright AF
Polasek O
Vatavuk Z
Wilson JF
Fleck B
Zeller T
Mirshahi A
Müller C
Uitterlinden AG
Rivadeneira F
Vingerling JR
Hofman A
Oostra BA
Amin N
Bergen AA
Teo YY
Rahi JS
Vitart V
Williams C
Baird PN
Wong TY
Oexle K
Pfeiffer N
Mackey DA
Young TL
van Duijn CM
Saw SM
Bailey-Wilson JE
Stambolian D
Klaver CC
Hammond CJ; Pokaż więcej
Corporate Authors:: Consortium for Refractive Error and Myopia (CREAM)
Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Research Group
Wellcome Trust Case Control Consortium 2 (WTCCC2)
Fuchs' Genetics Multi-Center Study Group
Źródło:: Nature genetics [Nat Genet] 2013 Mar; Vol. 45 (3), pp. 314-8. Date of Electronic Publication: 2013 Feb 10.
Typ publikacji:: Journal Article; Meta-Analysis; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Genome-Wide Association Study*
Myopia/*genetics
Refractive Errors/*genetics
Alcohol Oxidoreductases/genetics ; Asian People/genetics ; Bone Morphogenetic Protein 2/genetics ; Genetic Predisposition to Disease ; Homeodomain Proteins/genetics ; Humans ; KCNQ Potassium Channels/genetics ; Laminin/genetics ; Receptors, AMPA/genetics ; Risk Factors ; Serine Proteases/genetics ; Trans-Activators/genetics ; White People/genetics

Czasopismo naukowe

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Pełny tekst Szczegóły

Skocz do pozycji: 10.

Tytuł:: Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis.
Autorzy:: Holliday EG; Centre for Clinical Epidemiology and Biostatistics, and School of Medicine and Public Health, University of Newcastle, Newcastle, New South Wales, Australia. />Smith AV
Cornes BK
Buitendijk GH
Jensen RA
Sim X
Aspelund T
Aung T
Baird PN
Boerwinkle E
Cheng CY
van Duijn CM
Eiriksdottir G
Gudnason V
Harris T
Hewitt AW
Inouye M
Jonasson F
Klein BE
Launer L
Li X
Liew G
Lumley T
McElduff P
McKnight B
Mitchell P
Psaty BM
Rochtchina E
Rotter JI
Scott RJ
Tay W
Taylor K
Teo YY
Uitterlinden AG
Viswanathan A
Xie S
Vingerling JR
Klaver CC
Tai ES
Siscovick D
Klein R
Cotch MF
Wong TY
Attia J
Wang JJ; Pokaż więcej
Corporate Authors:: Wellcome Trust Case Control Consortium 2
Źródło:: PloS one [PLoS One] 2013; Vol. 8 (1), pp. e53830. Date of Electronic Publication: 2013 Jan 11.
Typ publikacji:: Journal Article; Meta-Analysis; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Genome-Wide Association Study*
Complement Factor H/*genetics
Macular Degeneration/*genetics
Proteins/*genetics
Apolipoproteins E/genetics ; Genetic Predisposition to Disease ; Genotype ; Humans ; Kruppel-Like Transcription Factors/genetics ; Nerve Tissue Proteins/genetics ; Polymorphism, Single Nucleotide ; Risk Factors ; Zinc Finger Protein Gli3

Czasopismo naukowe

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Pełny tekst Szczegóły

Skocz do pozycji: 11.

Tytuł:: Genome-wide association study of retinopathy in individuals without diabetes.
Autorzy:: Jensen RA; Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, United States of America. />Sim X
Li X
Cotch MF
Ikram MK
Holliday EG
Eiriksdottir G
Harris TB
Jonasson F
Klein BE
Launer LJ
Smith AV
Boerwinkle E
Cheung N
Hewitt AW
Liew G
Mitchell P
Wang JJ
Attia J
Scott R
Glazer NL
Lumley T
McKnight B
Psaty BM
Taylor K
Hofman A
de Jong PT
Rivadeneira F
Uitterlinden AG
Tay WT
Teo YY
Seielstad M
Liu J
Cheng CY
Saw SM
Aung T
Ganesh SK
O'Donnell CJ
Nalls MA
Wiggins KL
Kuo JZ
van Duijn CM
Gudnason V
Klein R
Siscovick DS
Rotter JI
Tai ES
Vingerling J
Wong TY; Pokaż więcej
Corporate Authors:: Blue Mountains Eye Study GWAS Team
CKDGen Consortium
Źródło:: PloS one [PLoS One] 2013; Vol. 8 (2), pp. e54232. Date of Electronic Publication: 2013 Feb 05.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Genome-Wide Association Study/*methods
Retinal Diseases/*genetics
Aged ; Aged, 80 and over ; Female ; Genotype ; Histone Deacetylases/genetics ; Humans ; Hypertension ; Male ; Polymorphism, Single Nucleotide/genetics ; Repressor Proteins/genetics

Czasopismo naukowe

na półce

Pełny tekst Szczegóły

Skocz do pozycji: 12.

Tytuł:: Genome-wide association analyses identify three new susceptibility loci for primary angle closure glaucoma.
Autorzy:: Vithana EN; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.; Department of Ophthalmology, National University Health System & National University of Singapore, Singapore.
Khor CC; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.; Department of Ophthalmology, National University Health System & National University of Singapore, Singapore.; Infectious Diseases, Genome Institute of Singapore, Singapore.; Human Genetics, Genome Institute of Singapore, Singapore.; Department of Paediatrics, National University Health System & National University of Singapore, Singapore.; Saw Swee Hock School of Public Health, National University of Singapore, Singapore.
Qiao C; Beijing Ophthalmology & Visual Sciences Key Laboratory, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Nongpiur ME; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.; Department of Ophthalmology, National University Health System & National University of Singapore, Singapore.
George R; Vision Research Foundation, Sankara Nethralaya, Chennai, India.
Chen LJ; Department of Ophthalmology & Visual Sciences, Chinese University of Hong Kong, Hong Kong, China.
Do T; Vietnam National Institute of Ophthalmology, Hanoi, Vietnam.
Abu-Amero K; Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia.; Department of Ophthalmology, College of Medicine, University of Florida, Jacksonville, Florida, USA.
Huang CK; Shantou University-Chinese University of Hong Kong Joint Shantou International Eye Center, Shantou, China.
Low S; National Institute for Health Research (NIHR) Biomedical Research Centre for Ophthalmology at Moorfields Eye Hospital and University College London (UCL) Institute of Ophthalmology, London, UK.
Tajudin LA; Department of Ophthalmology, School of Medical Sciences, Universiti Sains Malaysia, Kota Bharu, Malaysia.
Perera SA; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.
Cheng CY; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.; Department of Ophthalmology, National University Health System & National University of Singapore, Singapore.; Saw Swee Hock School of Public Health, National University of Singapore, Singapore.
Xu L; Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Jia H; Beijing Ophthalmology & Visual Sciences Key Laboratory, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Ho CL; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.
Sim KS; Human Genetics, Genome Institute of Singapore, Singapore.
Wu RY; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.; Xiamen Eye Centre, Xiamen University, Xiamen, China.
Tham CCY; Department of Ophthalmology & Visual Sciences, Chinese University of Hong Kong, Hong Kong, China.
Chew PTK; Department of Ophthalmology, National University Health System & National University of Singapore, Singapore.
Su DH; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.
Oen FT; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.
Sarangapani S; Vision Research Foundation, Sankara Nethralaya, Chennai, India.
Soumittra N; Vision Research Foundation, Sankara Nethralaya, Chennai, India.
Osman EA; Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Wong HT; Department of Ophthalmology, Tan Tock Seng Hospital, Singapore.
Tang G; Xingtai Eye Hospital, Xingtai, China.
Fan S; Handan Eye Hospital, Handan, China.
Meng H; Anyang Eye Hospital, Anyang, China.
Huong DTL; Vietnam National Institute of Ophthalmology, Hanoi, Vietnam.
Wang H; Beijing Ophthalmology & Visual Sciences Key Laboratory, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Feng B; Beijing Ophthalmology & Visual Sciences Key Laboratory, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Baskaran M; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.
Shantha B; Vision Research Foundation, Sankara Nethralaya, Chennai, India.
Ramprasad VL; Vision Research Foundation, Sankara Nethralaya, Chennai, India.
Kumaramanickavel G; Vision Research Foundation, Sankara Nethralaya, Chennai, India.
Iyengar SK; Department of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, Ohio, USA.
How AC; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.
Lee KY; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.
Sivakumaran TA; Department of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, Ohio, USA.
Yong VHK; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.
Ting SML; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.
Li Y; Department of Ophthalmology, School of Medical Sciences, Universiti Sains Malaysia, Kota Bharu, Malaysia.
Wang YX; Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Tay WT; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.
Sim X; Centre for Molecular Epidemiology, National University of Singapore, Singapore.
Lavanya R; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.
Cornes BK; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.
Zheng YF; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.; Department of Ophthalmology, National University Health System & National University of Singapore, Singapore.
Wong TT; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.
Loon SC; Department of Ophthalmology, National University Health System & National University of Singapore, Singapore.
Yong VKY; Department of Ophthalmology, Tan Tock Seng Hospital, Singapore.
Waseem N; National Institute for Health Research (NIHR) Biomedical Research Centre for Ophthalmology at Moorfields Eye Hospital and University College London (UCL) Institute of Ophthalmology, London, UK.
Yaakub A; Department of Ophthalmology, School of Medical Sciences, Universiti Sains Malaysia, Kota Bharu, Malaysia.
Chia KS; Saw Swee Hock School of Public Health, National University of Singapore, Singapore.
Allingham RR; Department of Opthamology, Duke University Medical Center, Durham, North Carolina, USA.
Hauser MA; Department of Opthamology, Duke University Medical Center, Durham, North Carolina, USA.
Lam DSC; Department of Ophthalmology & Visual Sciences, Chinese University of Hong Kong, Hong Kong, China.
Hibberd ML; Infectious Diseases, Genome Institute of Singapore, Singapore.; Saw Swee Hock School of Public Health, National University of Singapore, Singapore.
Bhattacharya SS; National Institute for Health Research (NIHR) Biomedical Research Centre for Ophthalmology at Moorfields Eye Hospital and University College London (UCL) Institute of Ophthalmology, London, UK.
Zhang M; Shantou University-Chinese University of Hong Kong Joint Shantou International Eye Center, Shantou, China.
Teo YY; Human Genetics, Genome Institute of Singapore, Singapore.; Saw Swee Hock School of Public Health, National University of Singapore, Singapore.; Centre for Molecular Epidemiology, National University of Singapore, Singapore.
Tan DT; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.; Department of Ophthalmology, National University Health System & National University of Singapore, Singapore.
Jonas JB; Department of Ophthalmology, Medical Faculty Mannheim of the Ruprecht-Karls-University Heidelberg, Heidelberg, Germany.
Tai ES; Saw Swee Hock School of Public Health, National University of Singapore, Singapore.; Department of Medicine, National University Health System & National University of Singapore, Singapore.; Duke-National University of Singapore Graduate Medical School, Singapore.
Saw SM; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.; Saw Swee Hock School of Public Health, National University of Singapore, Singapore.
Hon DN; Vietnam National Institute of Ophthalmology, Hanoi, Vietnam.
Al-Obeidan SA; Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Liu J; Human Genetics, Genome Institute of Singapore, Singapore.; Saw Swee Hock School of Public Health, National University of Singapore, Singapore.
Chau TNB; Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.
Simmons CP; Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.; Centre for Tropical Medicine, Nuffield Department of Clinical Medicine, Oxford University, Oxford, UK.
Bei JX; State Key Laboratory of Oncology in Southern China, Guangzhou, China.; Department of Experimental Research, Sun Yat-Sen University Cancer Centre, Guangzhou, China.
Zeng YX; State Key Laboratory of Oncology in Southern China, Guangzhou, China.; Department of Experimental Research, Sun Yat-Sen University Cancer Centre, Guangzhou, China.; Peking Union Medical College, Chinese Academy of Medical Science, Beijing, China.
Foster PJ; National Institute for Health Research (NIHR) Biomedical Research Centre for Ophthalmology at Moorfields Eye Hospital and University College London (UCL) Institute of Ophthalmology, London, UK.
Vijaya L; Vision Research Foundation, Sankara Nethralaya, Chennai, India.
Wong TY; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.; Department of Ophthalmology, National University Health System & National University of Singapore, Singapore.; Saw Swee Hock School of Public Health, National University of Singapore, Singapore.
Pang CP; Department of Ophthalmology & Visual Sciences, Chinese University of Hong Kong, Hong Kong, China.
Wang N; Beijing Ophthalmology & Visual Sciences Key Laboratory, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Aung T; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.; Department of Ophthalmology, National University Health System & National University of Singapore, Singapore.; Pokaż więcej
Źródło:: Nature genetics [Nat Genet] 2012 Oct; Vol. 44 (10), pp. 1142-1146. Date of Electronic Publication: 2012 Aug 26.
Typ publikacji:: Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't
MeSH Terms:: Genetic Predisposition to Disease*
Genome-Wide Association Study*
Carrier Proteins/*genetics
Collagen Type XI/*genetics
Glaucoma, Angle-Closure/*genetics
Protein D-Aspartate-L-Isoaspartate Methyltransferase/*genetics
Case-Control Studies ; Genetic Loci ; Humans ; Logistic Models ; Polymorphism, Single Nucleotide ; Principal Component Analysis ; Repressor Proteins/genetics

Czasopismo naukowe

na półce

Pełny tekst Szczegóły

Skocz do pozycji: 13.

Tytuł:: A statistical method for region-based meta-analysis of genome-wide association studies in genetically diverse populations.
Autorzy:: Wang X; Department of Epidemiology and Public Health, National University of Singapore, Singapore.
Liu X
Sim X
Xu H
Khor CC
Ong RT
Tay WT
Suo C
Poh WT
Ng DP
Liu J
Aung T
Chia KS
Wong TY
Tai ES
Teo YY; Pokaż więcej
Źródło:: European journal of human genetics : EJHG [Eur J Hum Genet] 2012 Apr; Vol. 20 (4), pp. 469-75. Date of Electronic Publication: 2011 Nov 30.
Typ publikacji:: Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't
MeSH Terms:: Genetics, Population*
Genome-Wide Association Study/*methods
Data Interpretation, Statistical ; Diabetes Mellitus, Type 2/genetics ; Genotype ; Humans ; Linkage Disequilibrium ; Polymorphism, Single Nucleotide