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Wyświetlanie 1-20 z 90
Tytuł:
Selective lysine-specific demethylase 1 inhibitor, NCL1, could cause testicular toxicity via the regulation of apoptosis.
Autorzy:
Nozaki S; Department of Nephro-urology, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan.
Naiki T; Department of Nephro-urology, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan.
Naiki-Ito A; Department of Experimental Pathology and Tumor Biology, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan.
Iwatsuki S; Department of Nephro-urology, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan.
Takeda T; Department of Nephro-urology, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan.
Etani T; Department of Nephro-urology, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan.
Nagai T; Department of Nephro-urology, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan.
Iida K; Department of Nephro-urology, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan.
Kato H; Department of Experimental Pathology and Tumor Biology, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan.
Suzuki T; Department of Complex Molecular Chemistry, The Institute of Scientific and Industrial Research, Osaka University, Suita, Japan.
Takahashi S; Department of Experimental Pathology and Tumor Biology, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan.
Umemoto Y; Department of Nephro-urology, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan.; Department of Education and Research Center for Advanced Medicine, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan.
Yasui T; Department of Nephro-urology, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan.
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Źródło:
Andrology [Andrology] 2020 Nov; Vol. 8 (6), pp. 1895-1906. Date of Electronic Publication: 2020 Jul 15.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antineoplastic Agents/*adverse effects
Apoptosis/*drug effects
Infertility, Male/*chemically induced
Spermatogenesis/*drug effects
Testis/*pathology
Animals ; Antineoplastic Agents/pharmacology ; Cell Line ; Hematologic Neoplasms/drug therapy ; Histone Demethylases/antagonists & inhibitors ; Humans ; Male ; Mice ; Mice, Inbred C57BL ; Prostatic Neoplasms/drug therapy ; Sertoli Cells/metabolism ; Spermatozoa/metabolism ; Testis/drug effects ; Testosterone/blood
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Simulated microgravity enhances CDDP-induced apoptosis signal via p53-independent mechanisms in cancer cells.
Autorzy:
Fukazawa T; Natural Science Center for Basic Research and Development, Hiroshima University, Hiroshima, Japan.
Tanimoto K; Department of Radiation Disaster Medicine, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima, Japan.
Shrestha L; Division of Bio-Environmental Adaptation Sciences, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Imura T; Division of Bio-Environmental Adaptation Sciences, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Takahashi S; Department of Surgery, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Sueda T; Department of Surgery, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Hirohashi N; Department of Radiation Disaster Medicine, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima, Japan.
Hiyama E; Natural Science Center for Basic Research and Development, Hiroshima University, Hiroshima, Japan.
Yuge L; Division of Bio-Environmental Adaptation Sciences, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.; Space Bio-Laboratories Co., Ltd., Hiroshima, Japan.
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Źródło:
PloS one [PLoS One] 2019 Jul 19; Vol. 14 (7), pp. e0219363. Date of Electronic Publication: 2019 Jul 19 (Print Publication: 2019).
Typ publikacji:
Journal Article
MeSH Terms:
Weightlessness*
Apoptosis/*drug effects
Cisplatin/*pharmacology
Tumor Suppressor Protein p53/*metabolism
AMP-Activated Protein Kinases/metabolism ; Autophagy/drug effects ; Caspase 3/metabolism ; Cell Proliferation ; Cyclin-Dependent Kinase Inhibitor p21/metabolism ; Hep G2 Cells ; Humans ; Membrane Proteins/metabolism ; Mutation ; PTEN Phosphohydrolase/metabolism ; Signal Transduction/drug effects ; bcl-2-Associated X Protein/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Cytoprotective Effects of Lysophospholipids from Sea Cucumber Holothuria atra.
Autorzy:
Nishikawa Y; National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Inada-cho, Obihiro, Hokkaido, Japan.
Furukawa A; National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Inada-cho, Obihiro, Hokkaido, Japan.
Shiga I; National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Inada-cho, Obihiro, Hokkaido, Japan.
Muroi Y; Department of Basic Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine, Obihiro Hokkaido, Japan.
Ishii T; Department of Basic Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine, Obihiro Hokkaido, Japan.
Hongo Y; RIKEN Center for Sustainable Resource Science, Wako, Saitama, Japan.
Takahashi S; RIKEN Center for Sustainable Resource Science, Wako, Saitama, Japan.
Sugawara T; Division of Applied Biosciences, Graduate School of Agriculture, Kyoto University, Kyoto, Japan.
Koshino H; RIKEN Center for Sustainable Resource Science, Wako, Saitama, Japan.
Ohnishi M; Department of Food Science, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Japan.
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Źródło:
PloS one [PLoS One] 2015 Aug 14; Vol. 10 (8), pp. e0135701. Date of Electronic Publication: 2015 Aug 14 (Print Publication: 2015).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis/*drug effects
Cytoprotection/*drug effects
Holothuria/*chemistry
Lysophospholipids/*pharmacology
Macrophages/*metabolism
Oxidative Stress/*drug effects
Animals ; Cell Line ; Hydrogen Peroxide/pharmacology ; Lysophospholipids/chemistry ; Mice
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Molecular functions of metallothionein and its role in hematological malignancies.
Autorzy:
Takahashi S; Division of Hematology, Kitasato University School of Allied Health Sciences, 1-15-1 Kitasato, Minami-ku, Sagamihara, 252-0373, Japan.
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Źródło:
Journal of hematology & oncology [J Hematol Oncol] 2012 Jul 27; Vol. 5, pp. 41. Date of Electronic Publication: 2012 Jul 27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Apoptosis*
Drug Resistance, Neoplasm*
Hematologic Neoplasms/*metabolism
Hematologic Neoplasms/*pathology
Metallothionein/*metabolism
Animals ; Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
mTORC1 serves ER stress-triggered apoptosis via selective activation of the IRE1-JNK pathway.
Autorzy:
Kato H; Department of Molecular Signaling, Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, Chuo, Yamanashi 409-3898, Japan.
Nakajima S
Saito Y
Takahashi S
Katoh R
Kitamura M
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Źródło:
Cell death and differentiation [Cell Death Differ] 2012 Feb; Vol. 19 (2), pp. 310-20. Date of Electronic Publication: 2011 Jul 22.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis*
Endoplasmic Reticulum Stress*
MAP Kinase Signaling System*
JNK Mitogen-Activated Protein Kinases/*metabolism
Membrane Proteins/*metabolism
Protein Serine-Threonine Kinases/*metabolism
TOR Serine-Threonine Kinases/*metabolism
Transcription Factors/*metabolism
Animals ; Cell Line ; Enzyme Activation ; Kidney/enzymology ; Kidney/injuries ; Kidney/pathology ; Male ; Mice ; Mice, Inbred C57BL ; Phosphorylation ; Proto-Oncogene Proteins c-akt/metabolism ; Rats ; mTOR Associated Protein, LST8 Homolog
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Induction of apoptosis in the LNCaP human prostate carcinoma cell line and prostate adenocarcinomas of SV40T antigen transgenic rats by the Bowman-Birk inhibitor.
Autorzy:
Tang M; Department of Experimental Pathology and Tumor Biology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.
Asamoto M
Ogawa K
Naiki-Ito A
Sato S
Takahashi S
Shirai T
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Źródło:
Pathology international [Pathol Int] 2009 Nov; Vol. 59 (11), pp. 790-6.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Adenocarcinoma/*drug therapy
Antineoplastic Agents/*pharmacology
Apoptosis/*drug effects
Prostatic Neoplasms/*drug therapy
Trypsin Inhibitor, Bowman-Birk Soybean/*pharmacology
Animals ; Animals, Genetically Modified ; Blotting, Western ; Cell Line, Tumor ; Connexin 43/biosynthesis ; Connexin 43/drug effects ; Humans ; Immunohistochemistry ; In Situ Nick-End Labeling ; Male ; Rats
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Radiation-induced apoptosis in peritoneal resident macrophages of C3H mice: selective involvement of superoxide anion, but not other reactive oxygen species.
Autorzy:
Kubota Y; Environmental and Toxicological Sciences Research Group, National Institute of Radiological Sciences, Anagawa, Chiba, Japan. y_ />Takahashi S
Sato H
Suetomi K
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Źródło:
International journal of radiation biology [Int J Radiat Biol] 2005 Jun; Vol. 81 (6), pp. 459-72.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis/*radiation effects
Macrophages, Peritoneal/*radiation effects
Reactive Oxygen Species/*metabolism
Superoxides/*metabolism
Animals ; Catalase/physiology ; DNA Damage ; Female ; Free Radical Scavengers/pharmacology ; Hydrogen Peroxide/pharmacology ; Macrophages, Peritoneal/pathology ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C3H ; Mice, Inbred C57BL ; Superoxide Dismutase/physiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Radiation-induced tissue abnormalities in fetal brain are related to apoptosis immediately after irradiation.
Autorzy:
Kubota Y; Environmental and Toxicological Sciences Research Group, National Institute of Radiological Sciences, Chiba, Japan. y_ />Takahashi S
Sun XZ
Sato H
Aizawa S
Yoshida K
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Źródło:
International journal of radiation biology [Int J Radiat Biol] 2000 May; Vol. 76 (5), pp. 649-59.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis/*radiation effects
Brain/*embryology
Brain/*radiation effects
Animals ; Apoptosis/genetics ; Brain/abnormalities ; Brain/pathology ; Cell Death/radiation effects ; Cell Survival/radiation effects ; Dose-Response Relationship, Radiation ; Female ; Fetal Death/genetics ; Genes, p53/genetics ; Genotype ; In Situ Nick-End Labeling ; Mice ; Mice, Inbred C3H ; Mice, Knockout ; Neurons/radiation effects ; Pregnancy ; Time Factors
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
T-bet regulates differentiation of forkhead box protein 3 regulatory T cells in programmed cell death-1-deficient mice.
Autorzy:
Tahara, M.
Kondo, Y.
Yokosawa, M.
Tsuboi, H.
Takahashi, S.
Shibayama, S.
Matsumoto, I.
Sumida, T.
Pokaż więcej
Temat:
FORKHEAD transcription factors
APOPTOSIS
T cell differentiation
TRANSGENIC mice
DWARFISM
LABORATORY mice
Źródło:
Clinical & Experimental Immunology; Feb2015, Vol. 179 Issue 2, p197-209, 13p
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 1-20 z 90

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