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Tytuł:
Loss of SFXN1 mitigates lipotoxicity and predicts poor outcome in non-viral hepatocellular carcinoma.
Autorzy:
Yagi K; Department of Molecular Oncology, Graduate School of Medicine, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-Ku, Tokyo, 113-8519, Japan.; Department of Hepato-Biliary-Pancreatic Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
Shimada S; Department of Molecular Oncology, Graduate School of Medicine, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-Ku, Tokyo, 113-8519, Japan. .
Akiyama Y; Department of Molecular Oncology, Graduate School of Medicine, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-Ku, Tokyo, 113-8519, Japan.
Hatano M; Department of Molecular Oncology, Graduate School of Medicine, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-Ku, Tokyo, 113-8519, Japan.
Asano D; Department of Hepato-Biliary-Pancreatic Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
Ishikawa Y; Department of Hepato-Biliary-Pancreatic Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
Ueda H; Department of Hepato-Biliary-Pancreatic Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
Watanabe S; Department of Hepato-Biliary-Pancreatic Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
Akahoshi K; Department of Hepato-Biliary-Pancreatic Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
Ono H; Department of Hepato-Biliary-Pancreatic Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
Tanabe M; Department of Hepato-Biliary-Pancreatic Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
Tanaka S; Department of Molecular Oncology, Graduate School of Medicine, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-Ku, Tokyo, 113-8519, Japan. tanaka..; Department of Hepato-Biliary-Pancreatic Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan. tanaka..
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Źródło:
Scientific reports [Sci Rep] 2023 Jun 09; Vol. 13 (1), pp. 9449. Date of Electronic Publication: 2023 Jun 09.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Carcinoma, Hepatocellular*/pathology
Liver Neoplasms*/pathology
Metabolic Syndrome*/complications
Mice ; Animals ; Humans ; Reactive Oxygen Species ; Antiviral Agents/therapeutic use
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
MGMT is frequently inactivated in pancreatic NET-G2 and is associated with the therapeutic activity of STZ-based regimens.
Autorzy:
Yagi K; Department of Hepatobiliary and Pancreatic Surgery, Tokyo Medical and Dental University, Tokyo, Japan.
Ono H; Department of Hepatobiliary and Pancreatic Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-Ku, Tokyo, 113-8519, Japan. .
Kudo A; Department of Hepatobiliary and Pancreatic Surgery, Tokyo Medical and Dental University, Tokyo, Japan.
Kinowaki Y; Department of Comprehensive Pathology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.
Asano D; Department of Hepatobiliary and Pancreatic Surgery, Tokyo Medical and Dental University, Tokyo, Japan.
Watanabe S; Department of Hepatobiliary and Pancreatic Surgery, Tokyo Medical and Dental University, Tokyo, Japan.
Ishikawa Y; Department of Hepatobiliary and Pancreatic Surgery, Tokyo Medical and Dental University, Tokyo, Japan.
Ueda H; Department of Hepatobiliary and Pancreatic Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-Ku, Tokyo, 113-8519, Japan.
Akahoshi K; Department of Hepatobiliary and Pancreatic Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-Ku, Tokyo, 113-8519, Japan.
Tanaka S; Department of Molecular Oncology, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
Tanabe M; Department of Hepatobiliary and Pancreatic Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-Ku, Tokyo, 113-8519, Japan.
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Źródło:
Scientific reports [Sci Rep] 2023 May 09; Vol. 13 (1), pp. 7535. Date of Electronic Publication: 2023 May 09.
Typ publikacji:
Journal Article
MeSH Terms:
Liver Neoplasms*
Humans ; Clinical Protocols ; Mitotic Index ; O(6)-Methylguanine-DNA Methyltransferase ; DNA Modification Methylases/genetics ; Tumor Suppressor Proteins ; DNA Repair Enzymes
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Effect of fatty liver and fibrosis on hepatocellular carcinoma development in patients with chronic hepatitis B who received nucleic acid analog therapy.
Autorzy:
Keitoku T; Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan.; Department of Gastroenterology and Hepatology, Tokyo Medical and Dental University, Tokyo, Japan.
Tamaki N; Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan.
Kurosaki M; Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan.
Inada K; Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan.; Department of Gastroenterology and Hepatology, Tokyo Medical and Dental University, Tokyo, Japan.
Kirino S; Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan.; Department of Gastroenterology and Hepatology, Tokyo Medical and Dental University, Tokyo, Japan.
Uchihara N; Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan.
Suzuki K; Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan.; Department of Gastroenterology and Hepatology, Tokyo Medical and Dental University, Tokyo, Japan.
Tanaka Y; Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan.
Miyamoto H; Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan.; Department of Gastroenterology and Hepatology, Tokyo Medical and Dental University, Tokyo, Japan.
Ishido S; Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan.; Department of Gastroenterology and Hepatology, Tokyo Medical and Dental University, Tokyo, Japan.
Yamada M; Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan.; Department of Gastroenterology and Hepatology, Tokyo Medical and Dental University, Tokyo, Japan.
Nobusawa T; Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan.; Department of Gastroenterology and Hepatology, Tokyo Medical and Dental University, Tokyo, Japan.
Matsumoto H; Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan.; Department of Gastroenterology and Hepatology, Tokyo Medical and Dental University, Tokyo, Japan.
Higuchi M; Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan.
Takaura K; Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan.
Tanaka S; Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan.; Department of Gastroenterology and Hepatology, Tokyo Medical and Dental University, Tokyo, Japan.
Maeyashiki C; Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan.; Department of Gastroenterology and Hepatology, Tokyo Medical and Dental University, Tokyo, Japan.
Kaneko S; Department of Gastroenterology and Hepatology, Tokyo Medical and Dental University, Tokyo, Japan.
Yasui Y; Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan.
Takahashi Y; Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan.
Tsuchiya K; Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan.; Department of Gastroenterology and Hepatology, Tokyo Medical and Dental University, Tokyo, Japan.
Nakanishi H; Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan.; Department of Gastroenterology and Hepatology, Tokyo Medical and Dental University, Tokyo, Japan.
Asahina Y; Department of Gastroenterology and Hepatology, Tokyo Medical and Dental University, Tokyo, Japan.
Okamoto R; Department of Gastroenterology and Hepatology, Tokyo Medical and Dental University, Tokyo, Japan.
Izumi N; Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan.
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Źródło:
Journal of viral hepatitis [J Viral Hepat] 2023 Apr; Vol. 30 (4), pp. 297-302. Date of Electronic Publication: 2023 Jan 24.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Carcinoma, Hepatocellular*/epidemiology
Liver Neoplasms*/epidemiology
Hepatitis B, Chronic*/drug therapy
Fatty Liver*/complications
Nucleic Acids*/therapeutic use
Humans ; Risk Factors ; Liver Cirrhosis/complications ; Antiviral Agents/therapeutic use ; Retrospective Studies
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Response to antiviral therapy for chronic hepatitis C and risk of hepatocellular carcinoma occurrence in Japan: a systematic review and meta-analysis of observational studies.
Autorzy:
Yamagiwa Y; Division of Prevention, National Cancer Center Institute for Cancer Control, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.; Clinical Research Centers for Medicine, International University of Health and Welfare, Tokyo, Japan.
Tanaka K; Department of Preventive Medicine, Faculty of Medicine, Saga University, Saga, Japan.
Matsuo K; Division of Cancer Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Japan.
Wada K; Department of Epidemiology and Preventive Medicine, Gifu University Graduate School of Medicine, Gifu, Japan.
Lin Y; Department of Public Health, Aichi Medical University School of Medicine, Aichi, Japan.
Sugawara Y; Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan.
Mizoue T; Department of Epidemiology and Prevention, Center for Clinical Sciences, National Center for Global Health and Medicine, Tokyo, Japan.
Sawada N; Division of Cohort Research, National Cancer Center Institute for Cancer Control, Tokyo, Japan.
Takimoto H; Department of Nutritional Epidemiology, National Institute of Health and Nutrition, National Institute of Biomedical Innovation, Health and Nutrition, Tokyo, Japan.
Ito H; Division of Cancer Information and Control, Department of Preventive Medicine, Aichi Cancer Center Research Institute, Nagoya, Japan.
Kitamura T; Department of Social Medicine, Osaka University Graduate School of Medicine, Osaka, Japan.
Sakata R; Department of Epidemiology, Radiation Effects Research Foundation, Hiroshima, Japan.
Kimura T; Department of Public Health, Hokkaido University Graduate School of Medicine, Sapporo, Japan.
Tanaka S; Division of Prevention, National Cancer Center Institute for Cancer Control, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.
Inoue M; Division of Prevention, National Cancer Center Institute for Cancer Control, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan. .; Division of Cohort Research, National Cancer Center Institute for Cancer Control, Tokyo, Japan. .
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Corporate Authors:
Research Group for the Development and Evaluation of Cancer Prevention Strategies in Japan
Źródło:
Scientific reports [Sci Rep] 2023 Mar 01; Vol. 13 (1), pp. 3445. Date of Electronic Publication: 2023 Mar 01.
Typ publikacji:
Meta-Analysis; Systematic Review; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Hepatitis C, Chronic*
Carcinoma, Hepatocellular*
Liver Neoplasms*
Humans ; Japan ; Interferons ; Antiviral Agents
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Risk factors for and management of morbidity in pure laparoscopic resection of the right posterosuperior segments of the liver: A multicenter retrospective study.
Autorzy:
Shinkawa H; Department of Hepato-Biliary-Pancreatic Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan.
Hirokawa F; Department of General and Gastroenterological Surgery, Osaka Medical and Pharmaceutical University, Osaka, Japan.
Kaibori M; Department of Surgery, Hirakata Hospital, Kansai Medical University, Osaka, Japan.
Nomi T; Department of Surgery, Nara Medical University, Nara, Japan.
Ueno M; Second Department of Surgery, Wakayama Medical University, Wakayama, Japan.
Ikoma H; Division of Digestive Surgery, Department of Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Nakai T; Department of Surgery, Faculty of Medicine, Kindai University, Osaka, Japan.
Iida H; Division of Gastrointestinal, Breast, and General Surgery, Department of Surgery, Shiga University of Medical Science, Otsu, Japan.
Tanaka S; Department of Hepato-Biliary-Pancreatic Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan.
Komeda K; Department of General and Gastroenterological Surgery, Osaka Medical and Pharmaceutical University, Osaka, Japan.
Kosaka H; Department of Surgery, Hirakata Hospital, Kansai Medical University, Osaka, Japan.
Hokuto D; Department of Surgery, Nara Medical University, Nara, Japan.
Hayami S; Second Department of Surgery, Wakayama Medical University, Wakayama, Japan.
Morimura R; Division of Digestive Surgery, Department of Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Matsumoto M; Department of Surgery, Faculty of Medicine, Kindai University, Osaka, Japan.
Maehira H; Division of Gastrointestinal, Breast, and General Surgery, Department of Surgery, Shiga University of Medical Science, Otsu, Japan.
Takemura S; Department of Hepato-Biliary-Pancreatic Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan.
Kubo S; Department of Hepato-Biliary-Pancreatic Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan.
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Źródło:
Asian journal of endoscopic surgery [Asian J Endosc Surg] 2022 Jul; Vol. 15 (3), pp. 539-546. Date of Electronic Publication: 2022 Feb 15.
Typ publikacji:
Journal Article; Multicenter Study
MeSH Terms:
Carcinoma, Hepatocellular*/surgery
Laparoscopy*/adverse effects
Liver Neoplasms*/pathology
Hepatectomy/adverse effects ; Humans ; Length of Stay ; Liver Cirrhosis/etiology ; Liver Cirrhosis/surgery ; Morbidity ; Operative Time ; Postoperative Complications/epidemiology ; Postoperative Complications/etiology ; Postoperative Complications/surgery ; Retrospective Studies
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Clinical evaluation of Elecsys PIVKA-II for patients with advanced hepatocellular carcinoma.
Autorzy:
Kaneko S; Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan.
Kurosaki M; Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan.
Tsuchiya K; Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan.
Yasui Y; Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan.
Hayakawa Y; Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan.
Inada K; Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan.
Tanaka Y; Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan.
Ishido S; Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan.
Kirino S; Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan.
Yamashita K; Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan.
Nobusawa T; Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan.
Matsumoto H; Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan.
Kakegawa T; Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan.
Higuchi M; Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan.
Takaura K; Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan.
Tanaka S; Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan.
Maeyashiki C; Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan.
Tamaki N; Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan.
Takahashi Y; Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan.
Nakanishi H; Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan.
Izumi N; Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan.
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Źródło:
PloS one [PLoS One] 2022 Mar 10; Vol. 17 (3), pp. e0265235. Date of Electronic Publication: 2022 Mar 10 (Print Publication: 2022).
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Hepatocellular*/diagnosis
Liver Neoplasms*/diagnosis
Multiple Myeloma*
Biomarkers ; Biomarkers, Tumor ; Humans ; Prospective Studies ; Protein Precursors ; Prothrombin ; Vitamin K ; alpha-Fetoproteins/analysis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Intrinsic activation of β-catenin signaling by CRISPR/Cas9-mediated exon skipping contributes to immune evasion in hepatocellular carcinoma.
Autorzy:
Akasu M; Department of Molecular Oncology, Graduate School of Medicine, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan.; Department of Hepato-Biliary-Pancreatic Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
Shimada S; Department of Molecular Oncology, Graduate School of Medicine, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan. .
Kabashima A; Department of Molecular Oncology, Graduate School of Medicine, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan.
Akiyama Y; Department of Molecular Oncology, Graduate School of Medicine, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan.
Shimokawa M; Department of Molecular Oncology, Graduate School of Medicine, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan.
Akahoshi K; Department of Hepato-Biliary-Pancreatic Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
Kudo A; Department of Hepato-Biliary-Pancreatic Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
Yamaoka S; Department of Molecular Virology, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
Tanabe M; Department of Hepato-Biliary-Pancreatic Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
Tanaka S; Department of Molecular Oncology, Graduate School of Medicine, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan. tanaka..; Department of Hepato-Biliary-Pancreatic Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan. tanaka..
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Źródło:
Scientific reports [Sci Rep] 2021 Aug 24; Vol. 11 (1), pp. 16732. Date of Electronic Publication: 2021 Aug 24.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Exons*
Immune Evasion*
Carcinoma, Hepatocellular/*metabolism
Liver Neoplasms/*metabolism
Wnt Signaling Pathway/*genetics
beta Catenin/*metabolism
CRISPR-Cas Systems ; Carcinoma, Hepatocellular/immunology ; Carcinoma, Hepatocellular/pathology ; Humans ; Liver Neoplasms/immunology ; Liver Neoplasms/pathology ; Mutation ; beta Catenin/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
MUTYH is associated with hepatocarcinogenesis in a non-alcoholic steatohepatitis mouse model.
Autorzy:
Sakamoto H; Department of Medical Oncology, Sapporo Medical University School of Medicine, South-1, West-16, Chuo-ku, Sapporo, 060-8543, Japan.
Miyanishi K; Department of Medical Oncology, Sapporo Medical University School of Medicine, South-1, West-16, Chuo-ku, Sapporo, 060-8543, Japan. .
Tanaka S; Department of Medical Oncology, Sapporo Medical University School of Medicine, South-1, West-16, Chuo-ku, Sapporo, 060-8543, Japan.
Ito R; Department of Medical Oncology, Sapporo Medical University School of Medicine, South-1, West-16, Chuo-ku, Sapporo, 060-8543, Japan.
Hamaguchi K; Department of Medical Oncology, Sapporo Medical University School of Medicine, South-1, West-16, Chuo-ku, Sapporo, 060-8543, Japan.
Sakurada A; Department of Medical Oncology, Sapporo Medical University School of Medicine, South-1, West-16, Chuo-ku, Sapporo, 060-8543, Japan.
Sato M; Department of Medical Oncology, Sapporo Medical University School of Medicine, South-1, West-16, Chuo-ku, Sapporo, 060-8543, Japan.
Kubo T; Department of Medical Oncology, Sapporo Medical University School of Medicine, South-1, West-16, Chuo-ku, Sapporo, 060-8543, Japan.
Osuga T; Department of Medical Oncology, Sapporo Medical University School of Medicine, South-1, West-16, Chuo-ku, Sapporo, 060-8543, Japan.
Murase K; Department of Medical Oncology, Sapporo Medical University School of Medicine, South-1, West-16, Chuo-ku, Sapporo, 060-8543, Japan.
Takada K; Department of Medical Oncology, Sapporo Medical University School of Medicine, South-1, West-16, Chuo-ku, Sapporo, 060-8543, Japan.
Nakabeppu Y; Division of Neurofunctional Genomics, Department of Immunobiology and Neuroscience, Medical Institute of Bioregulation, Kyushu University, 3-1-1 Maidashi, Higashi-Ku, Fukuoka, 812-8582, Japan.
Kobune M; Department of Hematology, Sapporo Medical University School of Medicine, South-1, West-16, Chuo-ku, Sapporo, 060-8543, Japan.
Kato J; Department of Medical Oncology, Sapporo Medical University School of Medicine, South-1, West-16, Chuo-ku, Sapporo, 060-8543, Japan.
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Źródło:
Scientific reports [Sci Rep] 2021 Feb 11; Vol. 11 (1), pp. 3599. Date of Electronic Publication: 2021 Feb 11.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Carcinogenesis/*genetics
Carcinoma, Hepatocellular/*genetics
DNA Glycosylases/*genetics
Liver Neoplasms/*genetics
Non-alcoholic Fatty Liver Disease/*genetics
Animals ; Biomarkers, Tumor/genetics ; Carcinoma, Hepatocellular/etiology ; Carcinoma, Hepatocellular/pathology ; Cholesterol/metabolism ; Diet, High-Fat ; Disease Models, Animal ; Genetic Predisposition to Disease ; Humans ; Liver/metabolism ; Liver/pathology ; Liver Cirrhosis/genetics ; Liver Cirrhosis/pathology ; Liver Neoplasms/etiology ; Liver Neoplasms/pathology ; Mice ; Mice, Knockout ; Non-alcoholic Fatty Liver Disease/complications ; Non-alcoholic Fatty Liver Disease/pathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Persistent hepatocyte apoptosis promotes tumorigenesis from diethylnitrosamine-transformed hepatocytes through increased oxidative stress, independent of compensatory liver regeneration.
Autorzy:
Nozaki Y; Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, Japan.
Hikita H; Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, Japan.
Tanaka S; Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, Japan.
Fukumoto K; Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, Japan.
Urabe M; Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, Japan.
Sato K; Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, Japan.
Myojin Y; Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, Japan.
Doi A; Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, Japan.
Murai K; Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, Japan.
Sakane S; Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, Japan.
Saito Y; Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, Japan.
Kodama T; Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, Japan.
Sakamori R; Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, Japan.
Tatsumi T; Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, Japan.
Takehara T; Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, Japan. .
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Źródło:
Scientific reports [Sci Rep] 2021 Feb 09; Vol. 11 (1), pp. 3363. Date of Electronic Publication: 2021 Feb 09.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis/*drug effects
Carcinoma, Hepatocellular/*chemically induced
Cell Transformation, Neoplastic/*chemically induced
Diethylnitrosamine/*toxicity
Hepatocytes/*metabolism
Liver Neoplasms/*chemically induced
Liver Regeneration/*drug effects
Oxidative Stress/*drug effects
Animals ; Apoptosis/genetics ; Carcinoma, Hepatocellular/genetics ; Carcinoma, Hepatocellular/metabolism ; Cell Transformation, Neoplastic/genetics ; Cell Transformation, Neoplastic/metabolism ; Hepatocytes/pathology ; Liver Neoplasms/genetics ; Liver Neoplasms/metabolism ; Mice ; Mice, Knockout
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Attenuated effect of PNPLA3 on hepatic fibrosis by HSD17B13 in Japanese patients with non-alcoholic fatty liver disease.
Autorzy:
Seko Y; Department of Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Yamaguchi K; Department of Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Tochiki N; Department of Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Yano K; Department of Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Takahashi A; Department of Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Okishio S; Department of Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Kataoka S; Department of Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Okuda K; Department of Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Umemura A; Department of Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Moriguchi M; Department of Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Tanaka S; Center for Digestive and Liver Diseases, Nara City Hospital, Nara, Japan.
Mori K; Center for Digestive and Liver Diseases, Nara City Hospital, Nara, Japan.
Okanoue T; Department of Gastroenterology and Hepatology, Saiseikai Suita Hospital, Osaka, Japan.
Itoh Y; Department of Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
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Źródło:
Liver international : official journal of the International Association for the Study of the Liver [Liver Int] 2020 Jul; Vol. 40 (7), pp. 1686-1692. Date of Electronic Publication: 2020 May 12.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Liver Neoplasms*/pathology
Non-alcoholic Fatty Liver Disease*/epidemiology
Non-alcoholic Fatty Liver Disease*/genetics
Non-alcoholic Fatty Liver Disease*/pathology
Humans ; Japan/epidemiology ; Lipase/genetics ; Liver/pathology ; Liver Cirrhosis/genetics ; Liver Cirrhosis/pathology ; Membrane Proteins/genetics ; Polymorphism, Single Nucleotide
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Difficulty classifications of laparoscopic repeated liver resection in patients with recurrent hepatocellular carcinoma.
Autorzy:
Kinoshita M; Department of Hepato-Biliary-Pancreatic Surgery, Osaka City General Hospital, Osaka, Japan.
Kanazawa A; Department of Hepato-Biliary-Pancreatic Surgery, Osaka City General Hospital, Osaka, Japan.
Kodai S; Department of Hepato-Biliary-Pancreatic Surgery, Osaka City General Hospital, Osaka, Japan.
Shimizu S; Department of Hepato-Biliary-Pancreatic Surgery, Osaka City General Hospital, Osaka, Japan.
Murata A; Department of Hepato-Biliary-Pancreatic Surgery, Osaka City General Hospital, Osaka, Japan.
Nishio K; Department of Hepato-Biliary-Pancreatic Surgery, Osaka City General Hospital, Osaka, Japan.
Hamano G; Department of Hepato-Biliary-Pancreatic Surgery, Osaka City General Hospital, Osaka, Japan.
Shinkawa H; Department of Hepato-Biliary-Pancreatic Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan.
Tanaka S; Department of Hepato-Biliary-Pancreatic Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan.
Takemura S; Department of Hepato-Biliary-Pancreatic Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan.
Tsukamoto T; Department of Surgery, Osaka City Juso Hospital, Osaka, Japan.
Kubo S; Department of Hepato-Biliary-Pancreatic Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan.
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Źródło:
Asian journal of endoscopic surgery [Asian J Endosc Surg] 2020 Jul; Vol. 13 (3), pp. 366-374. Date of Electronic Publication: 2019 Aug 13.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Hepatocellular*/surgery
Laparoscopy*
Liver Neoplasms*/surgery
Hepatectomy ; Humans ; Postoperative Complications/epidemiology ; Retrospective Studies ; Treatment Outcome
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Stagnation of histopathological improvement is a predictor of hepatocellular carcinoma development after hepatitis C virus eradication.
Autorzy:
Motoyama H; Department of Hepatology, Graduate School of Medicine, Osaka City University, Osaka, Japan.
Tamori A; Department of Hepatology, Graduate School of Medicine, Osaka City University, Osaka, Japan.
Kubo S; Department of Hepato-Biliary-Pancreatic Surgery, Graduate School of Medicine, Osaka City University, Osaka, Japan.
Uchida-Kobayashi S; Department of Hepatology, Graduate School of Medicine, Osaka City University, Osaka, Japan.
Takemura S; Department of Hepato-Biliary-Pancreatic Surgery, Graduate School of Medicine, Osaka City University, Osaka, Japan.
Tanaka S; Department of Hepato-Biliary-Pancreatic Surgery, Graduate School of Medicine, Osaka City University, Osaka, Japan.
Ohfuji S; Department of Public Health, Graduate School of Medicine, Osaka City University, Osaka, Japan.
Teranishi Y; Department of Hepatology, Graduate School of Medicine, Osaka City University, Osaka, Japan.
Kozuka R; Department of Hepatology, Graduate School of Medicine, Osaka City University, Osaka, Japan.
Kawamura E; Department of Hepatology, Graduate School of Medicine, Osaka City University, Osaka, Japan.
Hagihara A; Department of Hepatology, Graduate School of Medicine, Osaka City University, Osaka, Japan.
Morikawa H; Department of Hepatology, Graduate School of Medicine, Osaka City University, Osaka, Japan.
Enomoto M; Department of Hepatology, Graduate School of Medicine, Osaka City University, Osaka, Japan.
Murakami Y; Department of Hepatology, Graduate School of Medicine, Osaka City University, Osaka, Japan.
Kawada N; Department of Hepatology, Graduate School of Medicine, Osaka City University, Osaka, Japan.
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Źródło:
PloS one [PLoS One] 2018 Mar 13; Vol. 13 (3), pp. e0194163. Date of Electronic Publication: 2018 Mar 13 (Print Publication: 2018).
Typ publikacji:
Journal Article; Observational Study; Research Support, Non-U.S. Gov't
MeSH Terms:
Antineoplastic Agents/*therapeutic use
Antiviral Agents/*therapeutic use
Carcinoma, Hepatocellular/*drug therapy
Hepacivirus/*drug effects
Hepatitis C/*drug therapy
Interferons/*therapeutic use
Liver Neoplasms/*drug therapy
Adult ; Carcinoma, Hepatocellular/complications ; Carcinoma, Hepatocellular/pathology ; Carcinoma, Hepatocellular/virology ; Collagen/analysis ; Cytoglobin ; Female ; Fibrosis ; Globins/analysis ; Hepacivirus/isolation & purification ; Hepatitis C/complications ; Hepatitis C/pathology ; Humans ; Liver/drug effects ; Liver/pathology ; Liver/virology ; Liver Neoplasms/complications ; Liver Neoplasms/pathology ; Liver Neoplasms/virology ; Male ; Middle Aged ; Sustained Virologic Response
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Risk estimation model for nonalcoholic fatty liver disease in the Japanese using multiple genetic markers.
Autorzy:
Kawaguchi T; Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Shima T; Department of Gastroenterology and Hepatology, Saiseikai Suita Hospital, Suita, Japan.
Mizuno M; Department of Gastroenterology and Hepatology, Saiseikai Suita Hospital, Suita, Japan.
Mitsumoto Y; Department of Gastroenterology and Hepatology, Saiseikai Suita Hospital, Suita, Japan.
Umemura A; Department of Gastroenterology and Hepatology, Saiseikai Suita Hospital, Suita, Japan.
Kanbara Y; Department of Surgery, Saiseikai Suita Hospital, Suita, Japan.
Tanaka S; Center of Hepatology, Nara Municipal Hospital, Nara, Japan.
Sumida Y; Center of Hepatology, Nara Municipal Hospital, Nara, Japan.
Yasui K; Department of Gastroenterology, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Takahashi M; Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Matsuo K; Division of Molecular and Clinical Epidemiology, Aichi Cancer Center Research Institute, Aichi, Japan.
Itoh Y; Department of Gastroenterology, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Tokushige K; Department of Internal Medicine and Gastroenterology, Tokyo Women's Medical University, Tokyo, Japan.
Hashimoto E; Department of Internal Medicine and Gastroenterology, Tokyo Women's Medical University, Tokyo, Japan.
Kiyosawa K; Department of Gastroenterology, Nagano Red Cross Hospital, Nagano, Japan.
Kawaguchi M; Department of Gastroenterology, Saiseikai Wakayama Hospital, Wakayama, Japan.
Itoh H; Department of Gastroenterology, Kure Saiseikai Hospital, Kure, Japan.
Uto H; Digestive and Life-style Related Disease, Kagoshima University Graduate School of Medicine and Dental Science, Kagoshima, Japan.
Komorizono Y; Department of Hepatology, Nanpuh Hospital, Kagoshima, Japan.
Shirabe K; Department of Surgery and Science, Graduate School of Medical Science, Kyushu University, Fukuoka, Japan.
Takami S; Department of Gastroenterology, Otsu Municipal Hospital, Otsu, Japan.
Takamura T; Disease Control and Homeostasis, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan.
Kawanaka M; Center of Liver Disease, Kawasaki Hospital, Kawasaki Medical School, Okayama, Japan.
Yamada R; Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Matsuda F; Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Okanoue T; Department of Gastroenterology and Hepatology, Saiseikai Suita Hospital, Suita, Japan.
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Źródło:
PloS one [PLoS One] 2018 Jan 31; Vol. 13 (1), pp. e0185490. Date of Electronic Publication: 2018 Jan 31 (Print Publication: 2018).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Genetic Markers*
Models, Biological*
Carcinoma, Hepatocellular/*genetics
Liver Neoplasms/*genetics
Non-alcoholic Fatty Liver Disease/*genetics
Alleles ; Genetic Predisposition to Disease ; Genome-Wide Association Study ; Humans ; Japan ; Non-alcoholic Fatty Liver Disease/epidemiology ; Polymorphism, Single Nucleotide ; Risk Factors
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Secure, low-cost technique for laparoscopic hepatic resection using the crush-clamp method with a bipolar sealer.
Autorzy:
Yamamoto T; Department of Surgery, Ishikiri Seiki Hospital, Higashiosaka, Japan.
Uenishi T; Department of Surgery, Ishikiri Seiki Hospital, Higashiosaka, Japan.
Kaneda K; Department of Surgery, Ishikiri Seiki Hospital, Higashiosaka, Japan.
Okawa M; Department of Surgery, Ishikiri Seiki Hospital, Higashiosaka, Japan.
Tanaka S; Department of Hepato-Biliary-Pancreatic Surgery, Osaka City University Graduate School of Medicine, Osaka City, Osaka, Japan.
Kubo S; Department of Hepato-Biliary-Pancreatic Surgery, Osaka City University Graduate School of Medicine, Osaka City, Osaka, Japan.
Pokaż więcej
Źródło:
Asian journal of endoscopic surgery [Asian J Endosc Surg] 2017 Feb; Vol. 10 (1), pp. 96-99.
Typ publikacji:
Journal Article
MeSH Terms:
Hepatectomy/*methods
Laparoscopy/*methods
Liver Neoplasms/*surgery
Adult ; Aged ; Aged, 80 and over ; Bile Duct Neoplasms/economics ; Bile Duct Neoplasms/surgery ; Bile Ducts, Intrahepatic ; Blood Loss, Surgical/prevention & control ; Blood Loss, Surgical/statistics & numerical data ; Carcinoma, Hepatocellular/economics ; Carcinoma, Hepatocellular/surgery ; Cholangiocarcinoma/economics ; Cholangiocarcinoma/surgery ; Female ; Hepatectomy/economics ; Hepatectomy/instrumentation ; Hospital Costs ; Humans ; Japan ; Laparoscopy/economics ; Laparoscopy/instrumentation ; Length of Stay/statistics & numerical data ; Liver Neoplasms/economics ; Male ; Middle Aged ; Operative Time ; Treatment Outcome
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Dominant Expression of DCLK1 in Human Pancreatic Cancer Stem Cells Accelerates Tumor Invasion and Metastasis.
Autorzy:
Ito H; Department of Molecular Oncology, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan.; Department of Hepato-Biliary-Pancreatic Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
Tanaka S; Department of Molecular Oncology, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan.; Department of Hepato-Biliary-Pancreatic Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
Akiyama Y; Department of Molecular Oncology, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
Shimada S; Department of Molecular Oncology, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
Adikrisna R; Department of Hepato-Biliary-Pancreatic Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
Matsumura S; Department of Hepato-Biliary-Pancreatic Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
Aihara A; Department of Hepato-Biliary-Pancreatic Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
Mitsunori Y; Department of Hepato-Biliary-Pancreatic Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
Ban D; Department of Hepato-Biliary-Pancreatic Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
Ochiai T; Department of Hepato-Biliary-Pancreatic Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
Kudo A; Department of Hepato-Biliary-Pancreatic Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
Arii S; Department of Hepato-Biliary-Pancreatic Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
Yamaoka S; Department of Molecular Virology, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
Tanabe M; Department of Hepato-Biliary-Pancreatic Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
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Źródło:
PloS one [PLoS One] 2016 Jan 14; Vol. 11 (1), pp. e0146564. Date of Electronic Publication: 2016 Jan 14 (Print Publication: 2016).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Intracellular Signaling Peptides and Proteins/*genetics
Liver Neoplasms/*metabolism
Neoplastic Stem Cells/*metabolism
Pancreatic Neoplasms/*metabolism
Protein Serine-Threonine Kinases/*genetics
Animals ; Cells, Cultured ; Doublecortin-Like Kinases ; Female ; Genes, Dominant ; Humans ; Intracellular Signaling Peptides and Proteins/metabolism ; Liver Neoplasms/genetics ; Liver Neoplasms/secondary ; Mice ; Mice, Inbred BALB C ; Neoplasm Invasiveness ; Pancreatic Neoplasms/genetics ; Pancreatic Neoplasms/pathology ; Protein Serine-Threonine Kinases/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Advances in reduced port laparoscopic liver resection.
Autorzy:
Ban D; Department of Hepatobiliary-Pancreatic Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
Kudo A
Irie T
Ochiai T
Aihara A
Matsumura S
Tanaka S
Tanabe M
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Źródło:
Asian journal of endoscopic surgery [Asian J Endosc Surg] 2015 Feb; Vol. 8 (1), pp. 11-5. Date of Electronic Publication: 2014 Dec 15.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Laparoscopes*
Hepatectomy/*methods
Laparoscopy/*methods
Liver Neoplasms/*surgery
Equipment Design ; Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Long-term outcomes of hepatic resection versus living donor liver transplantation for hepatocellular carcinoma: a propensity score-matching study.
Autorzy:
Kaido T; Division of Hepato-Biliary-Pancreatic and Transplant Surgery, Department of Surgery, Graduate School of Medicine, Kyoto University, Kyoto 606-8507, Japan.
Morita S; Clinical Research Center for Medical Equipment Development, Kyoto University Hospital, Kyoto 606-8507, Japan.
Tanaka S; Department of Pharmacoepidemiology, Graduate School of Medicine and Public Health, Kyoto University, Kyoto 606-8507, Japan.
Ogawa K; Division of Hepato-Biliary-Pancreatic and Transplant Surgery, Department of Surgery, Graduate School of Medicine, Kyoto University, Kyoto 606-8507, Japan.
Mori A; Division of Hepato-Biliary-Pancreatic and Transplant Surgery, Department of Surgery, Graduate School of Medicine, Kyoto University, Kyoto 606-8507, Japan.
Hatano E; Division of Hepato-Biliary-Pancreatic and Transplant Surgery, Department of Surgery, Graduate School of Medicine, Kyoto University, Kyoto 606-8507, Japan.
Uemoto S; Division of Hepato-Biliary-Pancreatic and Transplant Surgery, Department of Surgery, Graduate School of Medicine, Kyoto University, Kyoto 606-8507, Japan.
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Źródło:
Disease markers [Dis Markers] 2015; Vol. 2015, pp. 425926. Date of Electronic Publication: 2015 Apr 01.
Typ publikacji:
Comparative Study; Journal Article; Observational Study
MeSH Terms:
Carcinoma, Hepatocellular/*surgery
Liver Neoplasms/*surgery
Liver Transplantation/*adverse effects
Adult ; Aged ; Female ; Humans ; Liver Transplantation/statistics & numerical data ; Male ; Middle Aged ; Propensity Score
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
The tumor-suppressive miR-497-195 cluster targets multiple cell-cycle regulators in hepatocellular carcinoma.
Autorzy:
Furuta M; Department of Molecular Cytogenetics, Medical Research Institute and School of Biomedical Science, Tokyo Medical and Dental University, Tokyo, Japan.
Kozaki K
Tanimoto K
Tanaka S
Arii S
Shimamura T
Niida A
Miyano S
Inazawa J
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Źródło:
PloS one [PLoS One] 2013; Vol. 8 (3), pp. e60155. Date of Electronic Publication: 2013 Mar 27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Genes, Tumor Suppressor*
Multigene Family*
Carcinoma, Hepatocellular/*genetics
Cell Cycle/*genetics
Liver Neoplasms/*genetics
MicroRNAs/*genetics
Carcinoma, Hepatocellular/pathology ; Cell Line, Tumor ; Cell Proliferation ; Computational Biology ; Computer Simulation ; Gene Expression Regulation, Neoplastic ; High-Throughput Nucleotide Sequencing ; Humans ; Liver Neoplasms/pathology ; MicroRNAs/metabolism ; Molecular Sequence Annotation ; Reproducibility of Results
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Alterations of the SWI/SNF chromatin remodelling subunit-BRG1 and BRM in hepatocellular carcinoma.
Autorzy:
Endo M; Department of Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Yasui K
Zen Y
Gen Y
Zen K
Tsuji K
Dohi O
Mitsuyoshi H
Tanaka S
Taniwaki M
Nakanuma Y
Arii S
Yoshikawa T
Pokaż więcej
Źródło:
Liver international : official journal of the International Association for the Study of the Liver [Liver Int] 2013 Jan; Vol. 33 (1), pp. 105-17. Date of Electronic Publication: 2012 Oct 22.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Biomarkers, Tumor/*genetics
Carcinoma, Hepatocellular/*genetics
Chromosomal Proteins, Non-Histone/*genetics
DNA Helicases/*genetics
Liver Neoplasms/*genetics
Nuclear Proteins/*genetics
Transcription Factors/*genetics
Biomarkers, Tumor/metabolism ; Carcinoma, Hepatocellular/metabolism ; Carcinoma, Hepatocellular/mortality ; Cell Line, Tumor ; Chi-Square Distribution ; Chromosomal Proteins, Non-Histone/metabolism ; DNA Copy Number Variations ; DNA Helicases/metabolism ; DNA Mutational Analysis ; Female ; Gene Deletion ; Humans ; Immunohistochemistry ; Kaplan-Meier Estimate ; Liver Neoplasms/metabolism ; Liver Neoplasms/mortality ; Male ; Middle Aged ; Mutation, Missense ; Nuclear Proteins/metabolism ; Oligonucleotide Array Sequence Analysis ; Polymorphism, Single Nucleotide ; Prognosis ; Transcription Factors/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Loss of runt-related transcription factor 3 expression leads hepatocellular carcinoma cells to escape apoptosis.
Autorzy:
Nakanishi Y; Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine and Dentistry, 2-5-1 Shikata-cho, Okayama 700-8558, Japan.
Shiraha H
Nishina S
Tanaka S
Matsubara M
Horiguchi S
Iwamuro M
Takaoka N
Uemura M
Kuwaki K
Hagihara H
Toshimori J
Ohnishi H
Takaki A
Nakamura S
Kobayashi Y
Nouso K
Yagi T
Yamamoto K
Pokaż więcej
Źródło:
BMC cancer [BMC Cancer] 2011 Jan 04; Vol. 11, pp. 3. Date of Electronic Publication: 2011 Jan 04.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis*
Carcinoma, Hepatocellular/*metabolism
Core Binding Factor Alpha 3 Subunit/*metabolism
Liver Neoplasms/*metabolism
Adolescent ; Adult ; Aged ; Apoptosis Regulatory Proteins/genetics ; Apoptosis Regulatory Proteins/metabolism ; Bcl-2-Like Protein 11 ; Carcinoma, Hepatocellular/genetics ; Carcinoma, Hepatocellular/pathology ; Caspases/metabolism ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Core Binding Factor Alpha 3 Subunit/genetics ; Culture Media, Serum-Free/pharmacology ; Gene Expression Regulation, Neoplastic ; Hep G2 Cells ; Humans ; Immunoblotting ; Immunohistochemistry ; Liver Neoplasms/genetics ; Liver Neoplasms/pathology ; Membrane Proteins/genetics ; Membrane Proteins/metabolism ; Middle Aged ; Mutation ; Proto-Oncogene Proteins/genetics ; Proto-Oncogene Proteins/metabolism ; RNA Interference ; Reverse Transcriptase Polymerase Chain Reaction ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
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