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Wyświetlanie 1-5 z 5
Tytuł :
Patient-derived organoids and orthotopic xenografts of primary and recurrent gliomas represent relevant patient avatars for precision oncology.
Autorzy :
Golebiewska A; NORLUX Neuro-Oncology Laboratory, Department of Oncology, Luxembourg Institute of Health, 84, Val Fleuri, 1526, Luxembourg, Luxembourg.
Hau AC; NORLUX Neuro-Oncology Laboratory, Department of Oncology, Luxembourg Institute of Health, 84, Val Fleuri, 1526, Luxembourg, Luxembourg.
Oudin A; NORLUX Neuro-Oncology Laboratory, Department of Oncology, Luxembourg Institute of Health, 84, Val Fleuri, 1526, Luxembourg, Luxembourg.
Stieber D; NORLUX Neuro-Oncology Laboratory, Department of Oncology, Luxembourg Institute of Health, 84, Val Fleuri, 1526, Luxembourg, Luxembourg.; National Center of Genetics, Laboratoire National de Santé, 3555, Dudelange, Luxembourg.
Yabo YA; NORLUX Neuro-Oncology Laboratory, Department of Oncology, Luxembourg Institute of Health, 84, Val Fleuri, 1526, Luxembourg, Luxembourg.; Faculty of Science, Technology and Medicine, University of Luxembourg, 4367, Belvaux, Luxembourg.
Baus V; NORLUX Neuro-Oncology Laboratory, Department of Oncology, Luxembourg Institute of Health, 84, Val Fleuri, 1526, Luxembourg, Luxembourg.
Barthelemy V; NORLUX Neuro-Oncology Laboratory, Department of Oncology, Luxembourg Institute of Health, 84, Val Fleuri, 1526, Luxembourg, Luxembourg.
Klein E; NORLUX Neuro-Oncology Laboratory, Department of Oncology, Luxembourg Institute of Health, 84, Val Fleuri, 1526, Luxembourg, Luxembourg.
Bougnaud S; NORLUX Neuro-Oncology Laboratory, Department of Oncology, Luxembourg Institute of Health, 84, Val Fleuri, 1526, Luxembourg, Luxembourg.
Keunen O; NORLUX Neuro-Oncology Laboratory, Department of Oncology, Luxembourg Institute of Health, 84, Val Fleuri, 1526, Luxembourg, Luxembourg.; Quantitative Biology Unit, Luxembourg Institute of Health, 1445, Strassen, Luxembourg.
Wantz M; NORLUX Neuro-Oncology Laboratory, Department of Oncology, Luxembourg Institute of Health, 84, Val Fleuri, 1526, Luxembourg, Luxembourg.
Michelucci A; NORLUX Neuro-Oncology Laboratory, Department of Oncology, Luxembourg Institute of Health, 84, Val Fleuri, 1526, Luxembourg, Luxembourg.; Neuro-Immunology Group, Department of Oncology, Luxembourg Institute of Health, 1526, Luxembourg, Luxembourg.; Luxembourg Centre for Systems Biomedicine, University of Luxembourg, 4367, Belvaux, Luxembourg.
Neirinckx V; NORLUX Neuro-Oncology Laboratory, Department of Oncology, Luxembourg Institute of Health, 84, Val Fleuri, 1526, Luxembourg, Luxembourg.
Muller A; Quantitative Biology Unit, Luxembourg Institute of Health, 1445, Strassen, Luxembourg.
Kaoma T; Quantitative Biology Unit, Luxembourg Institute of Health, 1445, Strassen, Luxembourg.
Nazarov PV; Quantitative Biology Unit, Luxembourg Institute of Health, 1445, Strassen, Luxembourg.
Azuaje F; Quantitative Biology Unit, Luxembourg Institute of Health, 1445, Strassen, Luxembourg.
De Falco A; National Center of Genetics, Laboratoire National de Santé, 3555, Dudelange, Luxembourg.; Faculty of Science, Technology and Medicine, University of Luxembourg, 4367, Belvaux, Luxembourg.; Luxembourg Center of Neuropathology, Luxembourg, Luxembourg.
Flies B; National Center of Genetics, Laboratoire National de Santé, 3555, Dudelange, Luxembourg.
Richart L; Faculty of Science, Technology and Medicine, University of Luxembourg, 4367, Belvaux, Luxembourg.; Luxembourg Center of Neuropathology, Luxembourg, Luxembourg.; National Center of Pathology, Laboratoire National de Santé, 3555, Dudelange, Luxembourg.; Department of Oncology, Luxembourg Institute of Health, 1526, Luxembourg, Luxembourg.
Poovathingal S; Luxembourg Centre for Systems Biomedicine, University of Luxembourg, 4367, Belvaux, Luxembourg.
Arns T; Luxembourg Centre for Systems Biomedicine, University of Luxembourg, 4367, Belvaux, Luxembourg.
Grzyb K; Luxembourg Centre for Systems Biomedicine, University of Luxembourg, 4367, Belvaux, Luxembourg.
Mock A; Division of Experimental Neurosurgery, Department of Neurosurgery, University of Heidelberg, 69120, Heidelberg, Germany.; Department of Medical Oncology, National Center for Tumor Diseases (NCT) Heidelberg, Heidelberg University Hospital, 69120, Heidelberg, Germany.; German Cancer Research Center (DKFZ) Heidelberg, 69120, Heidelberg, Germany.; German Cancer Consortium (DKTK), 69120, Heidelberg, Germany.
Herold-Mende C; Division of Experimental Neurosurgery, Department of Neurosurgery, University of Heidelberg, 69120, Heidelberg, Germany.
Steino A; DelMar Pharmaceuticals, Inc., Vancouver, BC, Canada.; DelMar Pharmaceuticals, Inc., Menlo Park, CA, USA.
Brown D; DelMar Pharmaceuticals, Inc., Vancouver, BC, Canada.; DelMar Pharmaceuticals, Inc., Menlo Park, CA, USA.
May P; Luxembourg Centre for Systems Biomedicine, University of Luxembourg, 4367, Belvaux, Luxembourg.
Miletic H; Department of Biomedicine, University of Bergen, 5019, Bergen, Norway.; Department of Pathology, Haukeland University Hospital, Bergen, Norway.
Malta TM; Department of Neurosurgery, Henry Ford Health System, Detroit, MI, 48202, USA.
Noushmehr H; Department of Neurosurgery, Henry Ford Health System, Detroit, MI, 48202, USA.
Kwon YJ; Department of Oncology, Luxembourg Institute of Health, 1526, Luxembourg, Luxembourg.
Jahn W; German Cancer Consortium (DKTK), 01307, Dresden, Germany.; Core Unit for Molecular Tumor Diagnostics (CMTD), National Center for Tumor Diseases (NCT), 01307, Dresden, Germany.
Klink B; National Center of Genetics, Laboratoire National de Santé, 3555, Dudelange, Luxembourg.; Department of Oncology, Luxembourg Institute of Health, 1526, Luxembourg, Luxembourg.; German Cancer Consortium (DKTK), 01307, Dresden, Germany.; Core Unit for Molecular Tumor Diagnostics (CMTD), National Center for Tumor Diseases (NCT), 01307, Dresden, Germany.; Institute for Clinical Genetics, Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden, Fetscherstraße 74, 01307, Dresden, Germany.
Tanner G; Leeds Institute of Medical Research at St James's, St James's University Hospital, Leeds, UK.
Stead LF; Leeds Institute of Medical Research at St James's, St James's University Hospital, Leeds, UK.
Mittelbronn M; Luxembourg Centre for Systems Biomedicine, University of Luxembourg, 4367, Belvaux, Luxembourg.; Luxembourg Center of Neuropathology, Luxembourg, Luxembourg.; National Center of Pathology, Laboratoire National de Santé, 3555, Dudelange, Luxembourg.; Department of Oncology, Luxembourg Institute of Health, 1526, Luxembourg, Luxembourg.
Skupin A; Luxembourg Centre for Systems Biomedicine, University of Luxembourg, 4367, Belvaux, Luxembourg.
Hertel F; Luxembourg Centre for Systems Biomedicine, University of Luxembourg, 4367, Belvaux, Luxembourg.; Department of Neurosurgery, Centre Hospitalier Luxembourg, 1210, Luxembourg, Luxembourg.
Bjerkvig R; NORLUX Neuro-Oncology Laboratory, Department of Oncology, Luxembourg Institute of Health, 84, Val Fleuri, 1526, Luxembourg, Luxembourg.; Department of Biomedicine, University of Bergen, 5019, Bergen, Norway.
Niclou SP; NORLUX Neuro-Oncology Laboratory, Department of Oncology, Luxembourg Institute of Health, 84, Val Fleuri, 1526, Luxembourg, Luxembourg. .; Department of Biomedicine, University of Bergen, 5019, Bergen, Norway. .
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Źródło :
Acta neuropathologica [Acta Neuropathol] 2020 Dec; Vol. 140 (6), pp. 919-949. Date of Electronic Publication: 2020 Oct 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Czasopismo naukowe
Tytuł :
Decreasing formalin concentration improves quality of DNA extracted from formalin-fixed paraffin-embedded tissue specimens without compromising tissue morphology or immunohistochemical staining.
Autorzy :
Cummings M; Women's Health Research Group, Pathology & Data Analytics, Leeds Institute of Medical Research at St. James's, University of Leeds, Wellcome Trust Brenner Building, Leeds, UK.
King H; Women's Health Research Group, Pathology & Data Analytics, Leeds Institute of Medical Research at St. James's, University of Leeds, Wellcome Trust Brenner Building, Leeds, UK.
Hurst J; Women's Health Research Group, Pathology & Data Analytics, Leeds Institute of Medical Research at St. James's, University of Leeds, Wellcome Trust Brenner Building, Leeds, UK.
Tanner G; Women's Health Research Group, Pathology & Data Analytics, Leeds Institute of Medical Research at St. James's, University of Leeds, Wellcome Trust Brenner Building, Leeds, UK.
Khazin L; Women's Health Research Group, Pathology & Data Analytics, Leeds Institute of Medical Research at St. James's, University of Leeds, Wellcome Trust Brenner Building, Leeds, UK.
Thompson P; Department of Histopathology, St. James's University Hospital, Leeds, UK.
Gray A; Department of Histopathology, St. James's University Hospital, Leeds, UK.
Gahir N; Women's Health Research Group, Pathology & Data Analytics, Leeds Institute of Medical Research at St. James's, University of Leeds, Wellcome Trust Brenner Building, Leeds, UK.
Cartlidge C; Women's Health Research Group, Pathology & Data Analytics, Leeds Institute of Medical Research at St. James's, University of Leeds, Wellcome Trust Brenner Building, Leeds, UK.
Farooq Z; Women's Health Research Group, Pathology & Data Analytics, Leeds Institute of Medical Research at St. James's, University of Leeds, Wellcome Trust Brenner Building, Leeds, UK.
Raveendran K; Women's Health Research Group, Pathology & Data Analytics, Leeds Institute of Medical Research at St. James's, University of Leeds, Wellcome Trust Brenner Building, Leeds, UK.
Allen K; Women's Health Research Group, Pathology & Data Analytics, Leeds Institute of Medical Research at St. James's, University of Leeds, Wellcome Trust Brenner Building, Leeds, UK.; Department of Histopathology, St. James's University Hospital, Leeds, UK.
Rotimi O; Department of Histopathology, St. James's University Hospital, Leeds, UK.
Orsi NM; Women's Health Research Group, Pathology & Data Analytics, Leeds Institute of Medical Research at St. James's, University of Leeds, Wellcome Trust Brenner Building, Leeds, UK .
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Źródło :
Journal of clinical pathology [J Clin Pathol] 2020 Aug; Vol. 73 (8), pp. 514-518. Date of Electronic Publication: 2020 Jan 09.
Typ publikacji :
Journal Article
MeSH Terms :
DNA/*isolation & purification
Fixatives/*pharmacology
Formaldehyde/*pharmacology
Paraffin Embedding/*standards
Colonic Diseases/pathology ; Female ; Humans ; Immunohistochemistry/standards ; Liver Diseases/pathology ; Quality Improvement ; Staining and Labeling/standards ; Tissue Fixation/standards ; Uterine Diseases/pathology
Czasopismo naukowe
Tytuł :
Longitudinal molecular trajectories of diffuse glioma in adults.
Autorzy :
Barthel FP; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.; Department of Pathology, Brain Tumor Center Amsterdam, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Johnson KC; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.
Varn FS; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.
Moskalik AD; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.
Tanner G; Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, UK.
Kocakavuk E; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.; DKFZ Division of Translational Neurooncology at the West German Cancer Center, German Cancer Consortium Partner Site, University Hospital Essen, Essen, Germany.; Department of Neurosurgery, University Hospital Essen, Essen, Germany.
Anderson KJ; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.
Abiola O; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.
Aldape K; Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.
Alfaro KD; Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Alpar D; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.; 1st Department of Pathology and Experimental Cancer Research, Semmelweis University, Budapest, Hungary.
Amin SB; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.
Ashley DM; Preston Robert Tisch Brain Tumor Center at Duke, Duke University Medical Center, Durham, NC, USA.
Bandopadhayay P; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Broad Institute, Cambridge, MA, USA.
Barnholtz-Sloan JS; Department of Population and Quantitative Health Sciences, Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
Beroukhim R; Broad Institute, Cambridge, MA, USA.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
Bock C; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.; Department of Laboratory Medicine, Medical University of Vienna, Vienna, Austria.
Brastianos PK; Division of Neuro-Oncology, Massachusetts General Hospital, Boston, MA, USA.
Brat DJ; Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Brodbelt AR; Department of Neurosurgery, University of Liverpool & Walton Centre NHS Trust, Liverpool, UK.
Bruns AF; Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, UK.
Bulsara KR; Division of Neurosurgery, The University of Connecticut Health Center, Farmington, CT, USA.
Chakrabarty A; Department of Cellular and Molecular Pathology, Leeds Teaching Hospital NHS Trust, St James's University Hospital, Leeds, UK.
Chakravarti A; Department of Radiation Oncology, The Ohio State Comprehensive Cancer Center-Arthur G. James Cancer Hospital, Columbus, OH, USA.
Chuang JH; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.; Department of Genetics and Genome Sciences, UConn Health, Farmington, CT, USA.
Claus EB; Yale University School of Public Health, New Haven, CT, USA.; Department of Neurosurgery, Brigham and Women's Hospital, Boston, MA, USA.
Cochran EJ; Department of Pathology & Laboratory Medicine, Medical College of Wisconsin, Milwaukee, WI, USA.
Connelly J; Department of Neurology, Medical College of Wisconsin, Milwaukee, WI, USA.
Costello JF; Department of Neurosurgery, University of California San Francisco, San Francisco, CA, USA.
Finocchiaro G; Fondazione IRCCS Istituto Neurologico Besta, Milano, Italy.
Fletcher MN; Division of Molecular Genetics, Heidelberg Center for Personalized Oncology, German Cancer Research Consortium, German Cancer Research Center (DKFZ), Heidelberg, Germany.
French PJ; Department of Neurology, Erasmus MC - University Medical Center Rotterdam, Rotterdam, The Netherlands.
Gan HK; Olivia Newton-John Cancer Research Institute, Austin Health, Melbourne, Victoria, Australia.; La Trobe University School of Cancer Medicine, Heidelberg, Victoria, Australia.
Gilbert MR; Neuro-Oncology Branch, National Institutes of Health, Bethesda, MD, USA.
Gould PV; Anatomic Pathology Service, Hôpital de l'Enfant-Jésus, CHU de Québec-Université Laval, Quebec, Quebec, Canada.
Grimmer MR; Department of Neurosurgery, University of California San Francisco, San Francisco, CA, USA.
Iavarone A; Department of Neurology, Columbia University Medical Center, New York, NY, USA.; Department of Pathology and Cell Biology, Columbia University Medical Center, New York, NY, USA.; Institute for Cancer Genetics, Columbia University Medical Center, New York, NY, USA.
Ismail A; Department of Cellular and Molecular Pathology, Leeds Teaching Hospital NHS Trust, St James's University Hospital, Leeds, UK.
Jenkinson MD; Department of Neurosurgery, University of Liverpool & Walton Centre NHS Trust, Liverpool, UK.
Khasraw M; Cooperative Trials Group for Neuro-Oncology (COGNO) NHMRC Clinical Trials Centre, The University of Sydney, Sydney, New South Wales, Australia.
Kim H; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.
Kouwenhoven MCM; Department of Neurology, Brain Tumor Center Amsterdam, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
LaViolette PS; Department of Radiology, Medical College of Wisconsin, Milwaukee, WI, USA.
Li M; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.
Lichter P; Division of Molecular Genetics, Heidelberg Center for Personalized Oncology, German Cancer Research Consortium, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Ligon KL; Broad Institute, Cambridge, MA, USA.; Department of Oncologic Pathology, Dana-Farber Cancer Institute, Boston, MA, USA.
Lowman AK; Department of Radiology, Medical College of Wisconsin, Milwaukee, WI, USA.
Malta TM; Department of Neurosurgery, Henry Ford Health System, Henry Ford Cancer Institute, Detroit, MI, USA.
Mazor T; Department of Neurosurgery, University of California San Francisco, San Francisco, CA, USA.
McDonald KL; Cure Brain Cancer Biomarkers and Translational Research Group, Prince of Wales Clinical School, University of New South Wales, Sydney, New South Wales, Australia.
Molinaro AM; Department of Neurosurgery, University of California San Francisco, San Francisco, CA, USA.
Nam DH; Department of Neurosurgery, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, South Korea.; Institute for Refractory Cancer Research, Samsung Medical Center, Seoul, South Korea.
Nayyar N; Division of Neuro-Oncology, Massachusetts General Hospital, Boston, MA, USA.
Ng HK; Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong.
Ngan CY; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.
Niclou SP; Department of Oncology, Luxembourg Institute of Health, Luxembourg, Luxembourg.
Niers JM; Department of Neurology, Brain Tumor Center Amsterdam, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Noushmehr H; Department of Neurosurgery, Henry Ford Health System, Henry Ford Cancer Institute, Detroit, MI, USA.
Noorbakhsh J; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.
Ormond DR; Department of Neurosurgery, University of Colorado School of Medicine, Aurora, CO, USA.
Park CK; Department of Neurosurgery, Seoul National University College of Medicine, Seoul National University Hospital, Seoul, South Korea.
Poisson LM; Department of Public Health Sciences, Henry Ford Health System, Henry Ford Cancer Institute, Detroit, MI, USA.
Rabadan R; Department of Biomedical Informatics, Columbia University Medical Center, New York, NY, USA.; Department of Systems Biology, Columbia University, New York, NY, USA.
Radlwimmer B; Division of Molecular Genetics, Heidelberg Center for Personalized Oncology, German Cancer Research Consortium, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Rao G; Department of Neurosurgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Reifenberger G; Institute of Neuropathology, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
Sa JK; Institute for Refractory Cancer Research, Samsung Medical Center, Seoul, South Korea.
Schuster M; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.
Shaw BL; Division of Neuro-Oncology, Massachusetts General Hospital, Boston, MA, USA.
Short SC; Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, UK.
Smitt PAS; Department of Neurology, Erasmus MC - University Medical Center Rotterdam, Rotterdam, The Netherlands.
Sloan AE; Department of Neurological Surgery, University Hospitals Cleveland Medical Center, Case Western Reserve University, Cleveland, OH, USA.; Department of Neurosurgery, Case Western Reserve University, Cleveland, OH, USA.; Seidman Cancer Center and Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, OH, USA.
Smits M; Department of Radiology & Nuclear Medicine, Erasmus MC - University Medical Center Rotterdam, Rotterdam, The Netherlands.
Suzuki H; The Hospital for Sick Children, Toronto, ON, Canada.
Tabatabai G; Interdiscplinary Division of Neuro-Oncology, Hertie Institute for Clinical Brain Research, DKTK Partner Site Tübingen, Eberhard Karls University Tübingen, Tübingen, Germany.
Van Meir EG; Department of Neurosurgery, School of Medicine and Winship Cancer Institute of Emory University, Atlanta, GA, USA.
Watts C; Institute of Cancer Genome Sciences, Department of Neurosurgery, University of Birmingham, Birmingham, UK.
Weller M; Department of Neurology, University Hospital Zurich, Zurich, Switzerland.
Wesseling P; Department of Pathology, Brain Tumor Center Amsterdam, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.
Westerman BA; Department of Neurosurgery, Brain Tumor Center Amsterdam, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Widhalm G; Department of Neurosurgery, Medical University of Vienna, Vienna, Austria.
Woehrer A; Institute of Neurology, Medical University of Vienna, Vienna, Austria.
Yung WKA; Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Zadeh G; Division of Neurosurgery, Department of Surgery, University Health Network, Toronto, Ontario, Canada.
Huse JT; Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
De Groot JF; Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Stead LF; Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, UK.
Verhaak RGW; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA. .
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Corporate Authors :
GLASS Consortium
Źródło :
Nature [Nature] 2019 Dec; Vol. 576 (7785), pp. 112-120. Date of Electronic Publication: 2019 Nov 20.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Glioma/*genetics
Adult ; Chromosomes, Human, Pair 1 ; Chromosomes, Human, Pair 19 ; Disease Progression ; Glioma/pathology ; Humans ; Isocitrate Dehydrogenase/genetics ; Mutation ; Polymorphism, Single Nucleotide ; Recurrence
Czasopismo naukowe
Tytuł :
Simulation of heterogeneous tumour genomes with HeteroGenesis and in silico whole exome sequencing.
Autorzy :
Tanner G; Leeds Institute of Medical Research at St James's, St James's University Hospital, Leeds, UK.
Westhead DR; School of Molecular and Cellular Biology, University of Leeds, Leeds, UK.
Droop A; Leeds Institute of Data Analytics, University of Leeds, Leeds, UK.
Stead LF; Leeds Institute of Medical Research at St James's, St James's University Hospital, Leeds, UK.
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Źródło :
Bioinformatics (Oxford, England) [Bioinformatics] 2019 Aug 15; Vol. 35 (16), pp. 2850-2852.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Neoplasms*/genetics
Software*
Genome ; Genomics ; Humans ; Whole Exome Sequencing
Czasopismo naukowe
Tytuł :
How to analyse the spatiotemporal tumour samples needed to investigate cancer evolution: A case study using paired primary and recurrent glioblastoma.
Autorzy :
Droop A; MRC Medical Bioinformatics Centre, University of Leeds, Leeds, LS2 9NL, United Kingdom.
Bruns A; Leeds Institute of Cancer and Pathology, University of Leeds, Leeds, LS9 7TF, United Kingdom.
Tanner G; Leeds Institute of Cancer and Pathology, University of Leeds, Leeds, LS9 7TF, United Kingdom.
Rippaus N; Leeds Institute of Cancer and Pathology, University of Leeds, Leeds, LS9 7TF, United Kingdom.
Morton R; Leeds Institute of Cancer and Pathology, University of Leeds, Leeds, LS9 7TF, United Kingdom.
Harrison S; Leeds Institute of Cancer and Pathology, University of Leeds, Leeds, LS9 7TF, United Kingdom.
King H; Leeds Institute of Cancer and Pathology, University of Leeds, Leeds, LS9 7TF, United Kingdom.
Ashton K; Lancashire Teaching Hospitals NHS Trust, Royal Preston Hospital, Preston, PR2 9HT, United Kingdom.
Syed K; Walton Centre NHS Trust, Liverpool, L9 7LJ, United Kingdom.
Jenkinson MD; Walton Centre NHS Trust, Liverpool, L9 7LJ, United Kingdom.; Institute of Translational Medicine, University of Liverpool, Liverpool, L9 7LJ, United Kingdom.
Brodbelt A; Walton Centre NHS Trust, Liverpool, L9 7LJ, United Kingdom.
Chakrabarty A; Leeds Teaching Hospitals NHS Trust, St James's University Hospital, Leeds, LS9 7TF, United Kingdom.
Ismail A; Leeds Teaching Hospitals NHS Trust, St James's University Hospital, Leeds, LS9 7TF, United Kingdom.
Short S; Leeds Institute of Cancer and Pathology, University of Leeds, Leeds, LS9 7TF, United Kingdom.
Stead LF; Leeds Institute of Cancer and Pathology, University of Leeds, Leeds, LS9 7TF, United Kingdom.
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Źródło :
International journal of cancer [Int J Cancer] 2018 Apr 15; Vol. 142 (8), pp. 1620-1626. Date of Electronic Publication: 2017 Dec 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Glioblastoma/*genetics
Genotype ; Humans ; Mutation/genetics ; Neoplasm Recurrence, Local/genetics ; Phenotype
Czasopismo naukowe
    Wyświetlanie 1-5 z 5

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