- Tytuł:
-
Paeoniflorin induces G2/M cell cycle arrest and caspase-dependent
apoptosis through the upregulation of Bcl-2 X-associated protein and downregulation of B-cell lymphoma 2 in human osteosarcoma cells. - Autorzy:
- Źródło:
- Molecular medicine reports [Mol Med Rep] 2018 Apr; Vol. 17 (4), pp. 5095-5101. Date of Electronic Publication: 2018 Jan 22.
- Typ publikacji:
- Journal Article
- MeSH Terms:
-
Apoptosis /*drug effects
Caspases/*metabolism
G2 Phase Cell Cycle Checkpoints/*drug effects
Glucosides/*pharmacology
Monoterpenes/*pharmacology
Proto-Oncogene Proteins c-bcl-2/*metabolism
bcl-2-Associated X Protein/*metabolismApoptosis /genetics ; Biomarkers ; Bone Neoplasms/genetics ; Bone Neoplasms/metabolism ; Bone Neoplasms/pathology ; Bone Neoplasms/ultrastructure ; Cell Line, Tumor ; Cell Survival/drug effects ; Dose-Response Relationship, Drug ; Humans ; Osteosarcoma/genetics ; Osteosarcoma/metabolism ; Osteosarcoma/pathology ; Osteosarcoma/ultrastructure ; Proto-Oncogene Proteins c-bcl-2/genetics ; bcl-2-Associated X Protein/genetics
Czasopismo naukowe