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Wyświetlanie 1-20 z 36
Tytuł:
How intrinsic and extrinsic regulators of plasma cell survival might intersect for durable humoral immunity.
Autorzy:
Robinson MJ; Department of Immunology & Pathology, Alfred Medical Research and Education Precinct, Monash University, Melbourne, Vic., Australia.
Webster RH; Department of Immunology & Pathology, Alfred Medical Research and Education Precinct, Monash University, Melbourne, Vic., Australia.
Tarlinton DM; Department of Immunology & Pathology, Alfred Medical Research and Education Precinct, Monash University, Melbourne, Vic., Australia.
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Źródło:
Immunological reviews [Immunol Rev] 2020 Jul; Vol. 296 (1), pp. 87-103. Date of Electronic Publication: 2020 Jun 26.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Immunity, Humoral*
Immunologic Memory*
Immunomodulation*/genetics
Plasma Cells/*immunology
Plasma Cells/*metabolism
Animals ; Antibody Formation/genetics ; Antibody Formation/immunology ; Bone Marrow/immunology ; Bone Marrow/metabolism ; Cell Survival/genetics ; Cell Survival/immunology ; Cellular Microenvironment/immunology ; Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Dynein light chain regulates adaptive and innate B cell development by distinctive genetic mechanisms.
Autorzy:
King A; Molecular Genetics Unit, St. Vincent's Institute of Medical Research, Fitzroy, Victoria, Australia.; Department of Medicine (St. Vincent's Health), University of Melbourne, Fitzroy, Victoria, Australia.
Li L; Molecular Genetics Unit, St. Vincent's Institute of Medical Research, Fitzroy, Victoria, Australia.; Department of Medicine (St. Vincent's Health), University of Melbourne, Fitzroy, Victoria, Australia.
Wong DM; Molecular Genetics Unit, St. Vincent's Institute of Medical Research, Fitzroy, Victoria, Australia.
Liu R; Molecular Genetics Unit, St. Vincent's Institute of Medical Research, Fitzroy, Victoria, Australia.
Bamford R; Molecular Genetics Unit, St. Vincent's Institute of Medical Research, Fitzroy, Victoria, Australia.
Strasser A; Molecular Genetics of Cancer Division, The Walter and Eliza Hall Institute, Parkville, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Parkville, Victoria, Australia.
Tarlinton DM; Department of Immunology and Pathology, Monash University, Melbourne, Victoria, Australia.
Heierhorst J; Molecular Genetics Unit, St. Vincent's Institute of Medical Research, Fitzroy, Victoria, Australia.; Department of Medicine (St. Vincent's Health), University of Melbourne, Fitzroy, Victoria, Australia.
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Źródło:
PLoS genetics [PLoS Genet] 2017 Sep 18; Vol. 13 (9), pp. e1007010. Date of Electronic Publication: 2017 Sep 18 (Print Publication: 2017).
Typ publikacji:
Journal Article
MeSH Terms:
B-Lymphocytes/*metabolism
Dyneins/*genetics
Lymphoma, B-Cell/*genetics
Transcription Factors/*genetics
Animals ; B-Lymphocytes/immunology ; Cell Lineage/genetics ; Cytoplasmic Dyneins ; Dyneins/metabolism ; Gene Expression Regulation ; Humans ; Lymphocytes/metabolism ; Lymphocytes/pathology ; Lymphoma, B-Cell/pathology ; Mice ; Peritoneal Cavity ; Proto-Oncogene Proteins c-myc/genetics ; Transcription Factors/metabolism ; Tumor Suppressor Protein p53/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
How many memories does it take to make an SLE flare?
Autorzy:
Tarlinton DM; The Walter and Eliza Hall Institute of Medical Research, Parkville, Australia.
Smith KG; Department of Medicine and Cambridge Institute of Medical Research, University of Cambridge School of Clinical Medicine, Cambridge, UK.
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Źródło:
Nature immunology [Nat Immunol] 2015 Jul; Vol. 16 (7), pp. 685-7.
Typ publikacji:
News; Comment
MeSH Terms:
Cell Proliferation*
Antibody Diversity/*immunology
Antibody-Producing Cells/*immunology
Autoantibodies/*immunology
Lupus Erythematosus, Systemic/*immunology
Humans
Periodyk
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Transcriptional profiling of mouse B cell terminal differentiation defines a signature for antibody-secreting plasma cells.
Autorzy:
Shi W; 1] The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia. [2] Department of Computing and Information Systems, The University of Melbourne, Parkville, Victoria, Australia.
Liao Y; 1] The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia. [2] Department of Medical Biology, The University of Melbourne, Parkville, Victoria, Australia.
Willis SN; 1] The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia. [2] Department of Medical Biology, The University of Melbourne, Parkville, Victoria, Australia.
Taubenheim N; 1] The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia. [2] Department of Medical Biology, The University of Melbourne, Parkville, Victoria, Australia.
Inouye M; 1] The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia. [2] Department of Pathology, The University of Melbourne, Parkville, Victoria, Australia. [3] Department of Microbiology &Immunology, The University of Melbourne, Parkville, Victoria, Australia.
Tarlinton DM; 1] The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia. [2] Department of Medical Biology, The University of Melbourne, Parkville, Victoria, Australia.
Smyth GK; 1] The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia. [2] Department of Mathematics and Statistics, The University of Melbourne, Parkville, Victoria, Australia.
Hodgkin PD; 1] The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia. [2] Department of Medical Biology, The University of Melbourne, Parkville, Victoria, Australia.
Nutt SL; 1] The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia. [2] Department of Medical Biology, The University of Melbourne, Parkville, Victoria, Australia.
Corcoran LM; 1] The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia. [2] Department of Medical Biology, The University of Melbourne, Parkville, Victoria, Australia.
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Źródło:
Nature immunology [Nat Immunol] 2015 Jun; Vol. 16 (6), pp. 663-73. Date of Electronic Publication: 2015 Apr 20.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Transcriptome*
Cell Differentiation/*genetics
Plasma Cells/*cytology
Plasma Cells/*immunology
Animals ; B-Cell Maturation Antigen/genetics ; Cell Division/genetics ; Cell Movement/genetics ; Cells, Cultured ; Gene Expression Profiling ; Histone Code/genetics ; Lymphocyte Activation/genetics ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Positive Regulatory Domain I-Binding Factor 1 ; RNA/analysis ; Suppressor of Cytokine Signaling Proteins/genetics ; Transcription Factors/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
The generation of antibody-secreting plasma cells.
Autorzy:
Nutt SL; The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Melbourne, Victoria 3052, Australia, and the Department of Medical Biology, University of Melbourne, Victoria 3010, Australia.
Hodgkin PD; The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Melbourne, Victoria 3052, Australia, and the Department of Medical Biology, University of Melbourne, Victoria 3010, Australia.
Tarlinton DM; The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Melbourne, Victoria 3052, Australia, and the Department of Medical Biology, University of Melbourne, Victoria 3010, Australia.
Corcoran LM; The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Melbourne, Victoria 3052, Australia, and the Department of Medical Biology, University of Melbourne, Victoria 3010, Australia.
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Źródło:
Nature reviews. Immunology [Nat Rev Immunol] 2015 Mar; Vol. 15 (3), pp. 160-71. Date of Electronic Publication: 2015 Feb 20.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Antibodies/*immunology
B-Lymphocytes/*immunology
Cell Differentiation/*immunology
Plasma Cells/*metabolism
Antibody Formation/immunology ; Humans ; Plasma Cells/immunology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
CD19 differentially regulates BCR signalling through the recruitment of PI3K.
Autorzy:
Xu Y; The Walter and Eliza Hall Institute of Medical Research , Department of Medical Biology, The University of Melbourne , Australia .
Fairfax K
Light A
Huntington ND
Tarlinton DM
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Źródło:
Autoimmunity [Autoimmunity] 2014 Nov; Vol. 47 (7), pp. 430-7. Date of Electronic Publication: 2014 Jun 23.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antigens, CD19/*metabolism
B-Lymphocytes/*metabolism
Phosphatidylinositol 3-Kinases/*metabolism
Receptors, Antigen, B-Cell/*metabolism
Animals ; Antigens, CD19/genetics ; Antigens, CD19/immunology ; Enzyme Activation ; Lymphocyte Activation ; Mice, Inbred C57BL ; Receptors, Antigen, B-Cell/immunology ; Signal Transduction ; src-Family Kinases/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Immunology: To affinity and beyond.
Autorzy:
Tarlinton DM; Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3052, Australia, and in the Department of Medical Biology, University of Melbourne, Parkville.
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Źródło:
Nature [Nature] 2014 May 29; Vol. 509 (7502), pp. 573-4.
Typ publikacji:
Journal Article; Comment
MeSH Terms:
Clonal Selection, Antigen-Mediated*
B-Lymphocytes/*cytology
B-Lymphocytes/*metabolism
Germinal Center/*cytology
Germinal Center/*immunology
Somatic Hypermutation, Immunoglobulin/*genetics
Animals ; Male
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Wyświetlanie 1-20 z 36

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