Defective Biomechanics and Pharmacological Rescue of Human Cardiomyocytes with Filamin C Truncations.
Autorzy:
Lazzarino M; CNR-IOM, Area Science Park, 34149 Trieste, Italy.; Cardiovascular Institute, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA. Zanetti M; CNR-IOM, Area Science Park, 34149 Trieste, Italy.; Cardiovascular Institute, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA. Chen SN; Cardiovascular Institute, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA. Gao S; Cardiovascular Institute, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA. Peña B; Cardiovascular Institute, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.; Bioengineering Department, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA. Lam CK; Stanford Cardiovascular Institute, Stanford University, Stanford, CA 94305, USA. Wu JC; Stanford Cardiovascular Institute, Stanford University, Stanford, CA 94305, USA. TaylorMRG; Cardiovascular Institute, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA. Mestroni L; Cardiovascular Institute, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA. Sbaizero O; Cardiovascular Institute, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.; Engineering and Architecture Department, University of Trieste, 34127 Trieste, Italy.
Filamin C Deficiency Impairs Sarcomere Stability and Activates Focal Adhesion Kinase through PDGFRA Signaling in Induced Pluripotent Stem Cell-Derived Cardiomyocytes.
Autorzy:
Gao S; University of Colorado Cardiovascular Institute, University of Colorado-Anschutz Medical and Boulder Campuses, Aurora, CO 80045, USA. He L; University of Colorado Cardiovascular Institute, University of Colorado-Anschutz Medical and Boulder Campuses, Aurora, CO 80045, USA. Lam CK; Department of Biological Sciences, University of Delaware, Newark, NE 19716, USA. TaylorMRG; University of Colorado Cardiovascular Institute, University of Colorado-Anschutz Medical and Boulder Campuses, Aurora, CO 80045, USA. Mestroni L; University of Colorado Cardiovascular Institute, University of Colorado-Anschutz Medical and Boulder Campuses, Aurora, CO 80045, USA. Lombardi R; University of Colorado Cardiovascular Institute, University of Colorado-Anschutz Medical and Boulder Campuses, Aurora, CO 80045, USA.; Department of Advanced Biomedical Sciences, 'Federico II' University of Naples, 80138 Naples, Italy. Chen SN; University of Colorado Cardiovascular Institute, University of Colorado-Anschutz Medical and Boulder Campuses, Aurora, CO 80045, USA.
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Źródło:
Cells [Cells] 2024 Feb 02; Vol. 13 (3). Date of Electronic Publication: 2024 Feb 02.
Microfabricated cantilevers for parallelized cell-cell adhesion measurements.
Autorzy:
Zanetti M; CNR-IOM, Istituto Officina dei Materiali - Consiglio Nazionale delle Ricerche, 34149, Trieste, Italy.; University of Trieste, 34127, Trieste, Italy. Chen SN; Molecular Genetics, Cardiovascular Institute, University of Colorado Denver Anschutz Medical Campus, Aurora, CO, 80045-2507, USA. Conti M; CNR-IOM, Istituto Officina dei Materiali - Consiglio Nazionale delle Ricerche, 34149, Trieste, Italy.; University of Trieste, 34127, Trieste, Italy. TaylorMRG; Molecular Genetics, Cardiovascular Institute, University of Colorado Denver Anschutz Medical Campus, Aurora, CO, 80045-2507, USA. Sbaizero O; University of Trieste, 34127, Trieste, Italy. Mestroni L; Molecular Genetics, Cardiovascular Institute, University of Colorado Denver Anschutz Medical Campus, Aurora, CO, 80045-2507, USA. Lazzarino M; CNR-IOM, Istituto Officina dei Materiali - Consiglio Nazionale delle Ricerche, 34149, Trieste, Italy. .; Molecular Genetics, Cardiovascular Institute, University of Colorado Denver Anschutz Medical Campus, Aurora, CO, 80045-2507, USA. .
Compromised Biomechanical Properties, Cell-Cell Adhesion and Nanotubes Communication in Cardiac Fibroblasts Carrying the Lamin A/C D192G Mutation.
Autorzy:
Lachaize V; Department of Engineering and Architecture, University of Trieste, Via Valerio 10, 34127 Trieste, Italy. Peña B; CU-Cardiovascular Institute, University of Colorado Anschutz Medical Campus, 12700 E. 19th Ave., Aurora, CO 80045, USA.; Consortium for Fibrosis Research & Translation, Anschutz Medical Campus, University of Colorado, 12700 E. 19th Ave., Aurora, CO 80045, USA.; Bioengineering Department, University of Colorado Denver Anschutz Medical Campus, Bioscience 2 1270 E. Montview Ave., Suite 100, Aurora, CO 80045, USA. Ciubotaru C; Institute of Materials, National Research Council of Italy (CNR_IOM), Area Science Park Basovizza, 34149 Trieste, Italy. Cojoc D; Institute of Materials, National Research Council of Italy (CNR_IOM), Area Science Park Basovizza, 34149 Trieste, Italy. Chen SN; CU-Cardiovascular Institute, University of Colorado Anschutz Medical Campus, 12700 E. 19th Ave., Aurora, CO 80045, USA. TaylorMRG; CU-Cardiovascular Institute, University of Colorado Anschutz Medical Campus, 12700 E. 19th Ave., Aurora, CO 80045, USA. Mestroni L; CU-Cardiovascular Institute, University of Colorado Anschutz Medical Campus, 12700 E. 19th Ave., Aurora, CO 80045, USA. Sbaizero O; Department of Engineering and Architecture, University of Trieste, Via Valerio 10, 34127 Trieste, Italy.; CU-Cardiovascular Institute, University of Colorado Anschutz Medical Campus, 12700 E. 19th Ave., Aurora, CO 80045, USA.
Danon Disease-Associated LAMP-2 Deficiency Drives Metabolic Signature Indicative of Mitochondrial Aging and Fibrosis in Cardiac Tissue and hiPSC-Derived Cardiomyocytes.
Autorzy:
Del Favero G; Department of Food Chemistry and Toxicology, Faculty of Chemistry, University of Vienna, Währinger Straße, 38-40, 1090 Vienna, Austria.; Core Facility Multimodal Imaging University of Vienna, Währinger Straße, 38-40, 1090 Vienna, Austria. Bonifacio A; Department of Engineering and Architecture, University of Trieste, 34127 Trieste, Italy. Rowland TJ; Department of Molecular, Cellular, and Developmental Biology, University of Colorado Boulder, Boulder, CO 80309, USA. Gao S; Cardiovascular Institute and Adult Medical Genetics, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA. Song K; Cardiovascular Institute and Adult Medical Genetics, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA. Sergo V; Department of Engineering and Architecture, University of Trieste, 34127 Trieste, Italy. Adler ED; Department of Medicine, Division of Cardiology, University of California San Diego, 9500 Gilman Drive, Biomedical Research Facility, La Jolla, CA 92093, USA. Mestroni L; Cardiovascular Institute and Adult Medical Genetics, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA. Sbaizero O; Department of Engineering and Architecture, University of Trieste, 34127 Trieste, Italy. TaylorMRG; Cardiovascular Institute and Adult Medical Genetics, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Transcriptome analysis of human heart failure reveals dysregulated cell adhesion in dilated cardiomyopathy and activated immune pathways in ischemic heart failure.
Autorzy:
Sweet ME; Human Medical Genetics and Genomics, University of Colorado, Aurora, CO, USA. Cocciolo A; Cardiovascular Institute and Adult Medical Genetics Program, University of Colorado, Aurora, CO, USA. Slavov D; Cardiovascular Institute and Adult Medical Genetics Program, University of Colorado, Aurora, CO, USA. Jones KL; Department of Pediatrics, Section of Hematology, Oncology, and Bone Marrow Transplant, University of Colorado, Aurora, CO, USA. Sweet JR; Department of Statistics, E. & J. Gallo, Modesto, CA, USA. Graw SL; Cardiovascular Institute and Adult Medical Genetics Program, University of Colorado, Aurora, CO, USA. Reece TB; Department of Cardiothoracic Surgery, University of Colorado Hospital, Aurora, CO, USA. Ambardekar AV; Division of Cardiology, Department of Medicine, University of Colorado, Aurora, CO, USA. Bristow MR; Division of Cardiology, Department of Medicine, University of Colorado, Aurora, CO, USA. Mestroni L; Human Medical Genetics and Genomics, University of Colorado, Aurora, CO, USA.; Cardiovascular Institute and Adult Medical Genetics Program, University of Colorado, Aurora, CO, USA. TaylorMRG; Human Medical Genetics and Genomics, University of Colorado, Aurora, CO, USA. matthew.taylor@ucdenver.edu.; Cardiovascular Institute and Adult Medical Genetics Program, University of Colorado, Aurora, CO, USA. matthew.taylor@ucdenver.edu.
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Źródło:
BMC genomics [BMC Genomics] 2018 Nov 12; Vol. 19 (1), pp. 812. Date of Electronic Publication: 2018 Nov 12.
Idiopathic Scoliosis Families Highlight Actin-Based and Microtubule-Based Cellular Projections and Extracellular Matrix in Disease Etiology.
Autorzy:
Baschal EE; Department of Orthopedics, University of Colorado Anschutz Medical Campus, Aurora, CO . Terhune EA; Department of Orthopedics, University of Colorado Anschutz Medical Campus, Aurora, CO. Wethey CI; Department of Orthopedics, University of Colorado Anschutz Medical Campus, Aurora, CO. Baschal RM; Department of Orthopedics, University of Colorado Anschutz Medical Campus, Aurora, CO.; Musculoskeletal Research Center, Children's Hospital Colorado, Aurora, CO. Robinson KD; Department of Orthopedics, University of Colorado Anschutz Medical Campus, Aurora, CO. Cuevas MT; Department of Orthopedics, University of Colorado Anschutz Medical Campus, Aurora, CO. Pradhan S; Department of Orthopedics, University of Colorado Anschutz Medical Campus, Aurora, CO. Sutphin BS; Department of Orthopedics, University of Colorado Anschutz Medical Campus, Aurora, CO. TaylorMRG; Department of Cardiology, University of Colorado Anschutz Medical Campus, Aurora, CO. Gowan K; Department of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, CO. Pearson CG; Department of Cell and Developmental Biology, University of Colorado Anschutz Medical Campus, Aurora, CO. Niswander LA; Department of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, CO.; Department of Molecular, Cellular and Developmental Biology, University of Colorado Boulder, Boulder, CO. Jones KL; Department of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, CO. Miller NH; Department of Orthopedics, University of Colorado Anschutz Medical Campus, Aurora, CO.; Musculoskeletal Research Center, Children's Hospital Colorado, Aurora, CO.
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Źródło:
G3 (Bethesda, Md.) [G3 (Bethesda)] 2018 Jul 31; Vol. 8 (8), pp. 2663-2672. Date of Electronic Publication: 2018 Jul 31.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Danon disease for the cardiologist: case report and review of the literature.
Autorzy:
D'souza RS; Adult Medical Genetics Program and Division of Cardiology, University of Colorado Denver, Denver, CO, USA.; Department of Medicine, Reading Hospital, West Reading, PA, USA. Mestroni L; Adult Medical Genetics Program and Division of Cardiology, University of Colorado Denver, Denver, CO, USA. TaylorMRG; Adult Medical Genetics Program and Division of Cardiology, University of Colorado Denver, Denver, CO, USA.
Danon disease presenting with dilated cardiomyopathy and a complex phenotype.
Autorzy:
TaylorMRG; University of Colorado at Denver and Health Sciences Center, Aurora, CO, USA. matthew.taylor@uchsc.edu.; 12635 East Montview Blvd. Suite 100, Aurora, CO, 80045, USA. matthew.taylor@uchsc.edu. Ku L; University of Colorado at Denver and Health Sciences Center, Aurora, CO, USA. Slavov D; University of Colorado at Denver and Health Sciences Center, Aurora, CO, USA. Cavanaugh J; The Children's Hospital, Denver, CO, USA. Boucek M; The Children's Hospital, Denver, CO, USA. Zhu X; University of Colorado at Denver and Health Sciences Center, Aurora, CO, USA. Graw S; University of Colorado at Denver and Health Sciences Center, Aurora, CO, USA. Carniel E; University of Colorado at Denver and Health Sciences Center, Aurora, CO, USA. Barnes C; University of Colorado at Denver and Health Sciences Center, Aurora, CO, USA. Quan D; University of Colorado at Denver and Health Sciences Center, Aurora, CO, USA. Prall R; University of Colorado at Denver and Health Sciences Center, Aurora, CO, USA. Lovell MA; The Children's Hospital, Denver, CO, USA. Mierau G; The Children's Hospital, Denver, CO, USA. Ruegg P; University of Colorado at Denver and Health Sciences Center, Aurora, CO, USA. Mandava N; University of Colorado at Denver and Health Sciences Center, Aurora, CO, USA. Bristow MR; University of Colorado at Denver and Health Sciences Center, Aurora, CO, USA. Towbin JA; Baylor College of Medicine, Houston, TX, USA. Mestroni L; University of Colorado at Denver and Health Sciences Center, Aurora, CO, USA.
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