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Tytuł:: Linkage, whole genome sequence, and biological data implicate variants in RAB10 in Alzheimer's disease resilience.
Autorzy:: Ridge PG; Department of Biology, Brigham Young University, Provo, UT, 84602, USA.
Karch CM; Washington University School of Medicine, St. Louis, MO, 63110, USA.
Hsu S; Washington University School of Medicine, St. Louis, MO, 63110, USA.
Arano I; Department of Biology, Brigham Young University, Provo, UT, 84602, USA.
Teerlink CC; Division of Genetic Epidemiology, Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, UT, 84132, USA.
Ebbert MTW; Department of Biology, Brigham Young University, Provo, UT, 84602, USA.; Present address: Department of Neuroscience, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL, 32224, USA.
Gonzalez Murcia JD; Department of Biology, Brigham Young University, Provo, UT, 84602, USA.
Farnham JM; Division of Genetic Epidemiology, Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, UT, 84132, USA.
Damato AR; Washington University School of Medicine, St. Louis, MO, 63110, USA.
Allen M; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, 32224, USA.
Wang X; Department of Health Sciences Research, Mayo Clinic, Jacksonville, FL, 32224, USA.
Harari O; Washington University School of Medicine, St. Louis, MO, 63110, USA.
Fernandez VM; Washington University School of Medicine, St. Louis, MO, 63110, USA.
Guerreiro R; Department of Molecular Neuroscience, Institute of Neurology, University College London, London, UK.
Bras J; Department of Molecular Neuroscience, Institute of Neurology, University College London, London, UK.
Hardy J; Department of Molecular Neuroscience, Institute of Neurology, University College London, London, UK.
Munger R; Department of Nutrition, Dietetics, and Food Sciences, Utah State University, Logan, UT, 84322, USA.
Norton M; Department of Family Consumer & Human Development, Utah State University, Logan, UT, 84322, USA.
Sassi C; Department of Molecular Neuroscience, Institute of Neurology, University College London, London, UK.; National Institute on Aging, Bethesda, MD, 21224, USA.
Singleton A; National Institute on Aging, Bethesda, MD, 21224, USA.
Younkin SG; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, 32224, USA.
Dickson DW; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, 32224, USA.
Golde TE; Center for Translational Research in Neurodegenerative Disease, McKnight Brain Institute, University of Florida, Department of Neuroscience, Gainesville, FL, 32610, USA.
Price ND; Institute for Systems Biology, 401 Terry Avenue N, Seattle, WA, 98109, USA.
Ertekin-Taner N; Departments of Neurology and Neuroscience, Mayo Clinic, Jacksonville, FL, 32224, USA.
Cruchaga C; Washington University School of Medicine, St. Louis, MO, 63110, USA.
Goate AM; Departments of Neuroscience, Genetics and Genomic Sciences, and Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Corcoran C; Department of Mathematics and Statistics, Utah State University, Logan, UT, 84322, USA.
Tschanz J; Department of Psychology, Utah State University, Logan, UT, 84322, USA.
Cannon-Albright LA; Division of Genetic Epidemiology, Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, UT, 84132, USA.; George E. Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, UT, 84148, USA.
Kauwe JSK; Departments of Biology and Neuroscience, Brigham Young University, Provo, UT, 84602, USA. .; Pokaż więcej
Corporate Authors:: Alzheimer’s Disease Neuroimaging Initiative
Źródło:: Genome medicine [Genome Med] 2017 Nov 29; Vol. 9 (1), pp. 100. Date of Electronic Publication: 2017 Nov 29.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:: Alzheimer Disease/*genetics
rab GTP-Binding Proteins/*genetics
Aged, 80 and over ; Animals ; Brain/metabolism ; Cell Line, Tumor ; Female ; Gene Expression ; Genetic Predisposition to Disease ; Humans ; Male ; Mice ; Monomeric GTP-Binding Proteins/genetics ; Polymorphism, Single Nucleotide

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