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Wyświetlanie 1-20 z 34
Tytuł:
Treatment failure patterns are similar between p16- and p16+ oropharyngeal squamous cell carcinomas.
Autorzy:
Hamill CS; Department of Otolaryngology-Head and Neck Surgery University Hospitals Cleveland Medical Center, Case Western Reserve University School of Medicine Cleveland Ohio USA.
Muller RG; Department of Otolaryngology-Head and Neck Surgery University Hospitals Cleveland Medical Center, Case Western Reserve University School of Medicine Cleveland Ohio USA.
Clancy K; Department of Otolaryngology-Head and Neck Surgery University Hospitals Cleveland Medical Center, Case Western Reserve University School of Medicine Cleveland Ohio USA.
Vu B; University Hospitals Seidman Cancer Center Cleveland Ohio USA.
Gui S; University Hospitals Seidman Cancer Center Cleveland Ohio USA.
Thuener JE; Department of Otolaryngology-Head and Neck Surgery University Hospitals Cleveland Medical Center, Case Western Reserve University School of Medicine Cleveland Ohio USA.; University Hospitals Seidman Cancer Center Cleveland Ohio USA.
Wasman J; University Hospitals Seidman Cancer Center Cleveland Ohio USA.; Department of Pathology University Hospitals Cleveland Medical Center, Case Western Reserve University School of Medicine Cleveland Ohio USA.
Li S; Department of Otolaryngology-Head and Neck Surgery University Hospitals Cleveland Medical Center, Case Western Reserve University School of Medicine Cleveland Ohio USA.; University Hospitals Seidman Cancer Center Cleveland Ohio USA.
Fowler N; Department of Otolaryngology-Head and Neck Surgery University Hospitals Cleveland Medical Center, Case Western Reserve University School of Medicine Cleveland Ohio USA.; University Hospitals Seidman Cancer Center Cleveland Ohio USA.
Rezaee R; Department of Otolaryngology-Head and Neck Surgery University Hospitals Cleveland Medical Center, Case Western Reserve University School of Medicine Cleveland Ohio USA.; University Hospitals Seidman Cancer Center Cleveland Ohio USA.
Lavertu P; Department of Otolaryngology-Head and Neck Surgery University Hospitals Cleveland Medical Center, Case Western Reserve University School of Medicine Cleveland Ohio USA.; University Hospitals Seidman Cancer Center Cleveland Ohio USA.
Teknos TN; Department of Otolaryngology-Head and Neck Surgery University Hospitals Cleveland Medical Center, Case Western Reserve University School of Medicine Cleveland Ohio USA.; University Hospitals Seidman Cancer Center Cleveland Ohio USA.; Case Comprehensive Cancer Center Case Western Reserve University School of Medicine Cleveland Ohio USA.
Pan Q; Department of Otolaryngology-Head and Neck Surgery University Hospitals Cleveland Medical Center, Case Western Reserve University School of Medicine Cleveland Ohio USA.; University Hospitals Seidman Cancer Center Cleveland Ohio USA.; Case Comprehensive Cancer Center Case Western Reserve University School of Medicine Cleveland Ohio USA.
O'Neill WQ; Department of Otolaryngology-Head and Neck Surgery University Hospitals Cleveland Medical Center, Case Western Reserve University School of Medicine Cleveland Ohio USA.; University Hospitals Seidman Cancer Center Cleveland Ohio USA.
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Źródło:
Laryngoscope investigative otolaryngology [Laryngoscope Investig Otolaryngol] 2022 Jun 01; Vol. 7 (4), pp. 988-993. Date of Electronic Publication: 2022 Jun 01 (Print Publication: 2022).
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Repositioning Fenofibrate to Reactivate p53 and Reprogram the Tumor-Immune Microenvironment in HPV+ Head and Neck Squamous Cell Carcinoma.
Autorzy:
O'Neill WQ; University Hospitals Seidman Cancer Center, Cleveland, OH 44106, USA.; Department of Otolaryngology-Head and Neck Surgery, University Hospitals, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.
Xie X; Department of Otolaryngology-Head and Neck Surgery, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA.
Gui S; University Hospitals Seidman Cancer Center, Cleveland, OH 44106, USA.
Yu H; Department of Otolaryngology-Head and Neck Surgery, University Hospitals, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.
Davenport J; Department of Otolaryngology-Head and Neck Surgery, University Hospitals, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.
Cartwright T; Department of Otolaryngology-Head and Neck Surgery, University Hospitals, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.
Storl-Desmond M; Department of Otolaryngology-Head and Neck Surgery, University Hospitals, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.
Ryu E; Department of Otolaryngology-Head and Neck Surgery, University Hospitals, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.
Chan ER; Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.
Cao S; Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.
Fu P; Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.
Teknos TN; University Hospitals Seidman Cancer Center, Cleveland, OH 44106, USA.; Department of Otolaryngology-Head and Neck Surgery, University Hospitals, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.; Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.
Pan Q; University Hospitals Seidman Cancer Center, Cleveland, OH 44106, USA.; Department of Otolaryngology-Head and Neck Surgery, University Hospitals, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.; Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.
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Źródło:
Cancers [Cancers (Basel)] 2022 Jan 07; Vol. 14 (2). Date of Electronic Publication: 2022 Jan 07.
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Impact of p16 Status and Anatomical Site in Anti-PD-1 Immunotherapy-Treated Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma Patients.
Autorzy:
Clancy K; Department of Otolaryngology-Head and Neck Surgery, University Hospitals Cleveland Medical Center, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.
Hamill CS; Department of Otolaryngology-Head and Neck Surgery, University Hospitals Cleveland Medical Center, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.
O'Neill WQ; Department of Otolaryngology-Head and Neck Surgery, University Hospitals Cleveland Medical Center, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.; University Hospitals Seidman Cancer Center, Cleveland, OH 44106, USA.
Vu B; University Hospitals Seidman Cancer Center, Cleveland, OH 44106, USA.
Thuener J; Department of Otolaryngology-Head and Neck Surgery, University Hospitals Cleveland Medical Center, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.; University Hospitals Seidman Cancer Center, Cleveland, OH 44106, USA.
Gui S; University Hospitals Seidman Cancer Center, Cleveland, OH 44106, USA.
Li S; Department of Otolaryngology-Head and Neck Surgery, University Hospitals Cleveland Medical Center, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.; University Hospitals Seidman Cancer Center, Cleveland, OH 44106, USA.
Fowler N; Department of Otolaryngology-Head and Neck Surgery, University Hospitals Cleveland Medical Center, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.; University Hospitals Seidman Cancer Center, Cleveland, OH 44106, USA.
Rezaee R; Department of Otolaryngology-Head and Neck Surgery, University Hospitals Cleveland Medical Center, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.; University Hospitals Seidman Cancer Center, Cleveland, OH 44106, USA.
Lavertu P; Department of Otolaryngology-Head and Neck Surgery, University Hospitals Cleveland Medical Center, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.; University Hospitals Seidman Cancer Center, Cleveland, OH 44106, USA.
Wasman J; University Hospitals Seidman Cancer Center, Cleveland, OH 44106, USA.; Department of Pathology, University Hospitals Cleveland Medical Center, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.
Patel M; University Hospitals Seidman Cancer Center, Cleveland, OH 44106, USA.; Department of Medicine, University Hospitals Cleveland Medical Center, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.
Shaikh H; Department of Internal Medicine, Division of Hematology/Oncology, University of Cincinnati, Cincinnati, OH 45267, USA.
Vick E; Department of Internal Medicine, Division of Hematology/Oncology, University of Cincinnati, Cincinnati, OH 45267, USA.
Madabhushi A; Department of Biomedical Engineering, Case Western University School of Engineering, Cleveland, OH 44106, USA.; Louis Stokes Cleveland Veterans Administration Medical Center, Cleveland, OH 44106, USA.; Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.
Wise-Draper TM; Department of Internal Medicine, Division of Hematology/Oncology, University of Cincinnati, Cincinnati, OH 45267, USA.
Burkitt K; University Hospitals Seidman Cancer Center, Cleveland, OH 44106, USA.; Department of Medicine, University Hospitals Cleveland Medical Center, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.
Teknos TN; Department of Otolaryngology-Head and Neck Surgery, University Hospitals Cleveland Medical Center, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.; University Hospitals Seidman Cancer Center, Cleveland, OH 44106, USA.; Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.
Pan Q; Department of Otolaryngology-Head and Neck Surgery, University Hospitals Cleveland Medical Center, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.; University Hospitals Seidman Cancer Center, Cleveland, OH 44106, USA.; Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.
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Źródło:
Cancers [Cancers (Basel)] 2021 Sep 28; Vol. 13 (19). Date of Electronic Publication: 2021 Sep 28.
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
p53 functional states are associated with distinct aldehyde dehydrogenase transcriptomic signatures.
Autorzy:
Gui S; University Hospitals Seidman Cancer Center, Cleveland, OH, 44106, USA.; Department of Otolaryngology-Head and Neck Surgery, Case Western Reserve University, School of Medicine, Cleveland, OH, 44106, USA.
Xie X; Department of Internal Medicine, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
O'Neill WQ; University Hospitals Seidman Cancer Center, Cleveland, OH, 44106, USA.; Department of Otolaryngology-Head and Neck Surgery, Case Western Reserve University, School of Medicine, Cleveland, OH, 44106, USA.
Chatfield-Reed K; University Hospitals Seidman Cancer Center, Cleveland, OH, 44106, USA.; Department of Otolaryngology-Head and Neck Surgery, Case Western Reserve University, School of Medicine, Cleveland, OH, 44106, USA.
Yu JG; Department of Otolaryngology-Head and Neck Surgery, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
Teknos TN; University Hospitals Seidman Cancer Center, Cleveland, OH, 44106, USA.; Department of Otolaryngology-Head and Neck Surgery, Case Western Reserve University, School of Medicine, Cleveland, OH, 44106, USA.; Case Comprehensive Cancer Center, Case Western Reserve University, School of Medicine, Cleveland, OH, 44106, USA.
Pan Q; University Hospitals Seidman Cancer Center, Cleveland, OH, 44106, USA. .; Department of Otolaryngology-Head and Neck Surgery, Case Western Reserve University, School of Medicine, Cleveland, OH, 44106, USA. .; Case Comprehensive Cancer Center, Case Western Reserve University, School of Medicine, Cleveland, OH, 44106, USA. .
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Źródło:
Scientific reports [Sci Rep] 2020 Jan 23; Vol. 10 (1), pp. 1097. Date of Electronic Publication: 2020 Jan 23.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Aldehyde Dehydrogenase/*genetics
Papillomavirus Infections/*metabolism
Tumor Suppressor Protein p53/*metabolism
Aldehyde Dehydrogenase/metabolism ; Animals ; Female ; Human papillomavirus 16/genetics ; Human papillomavirus 16/physiology ; Humans ; Isoenzymes/genetics ; Isoenzymes/metabolism ; Mice ; Neoplastic Stem Cells/metabolism ; Oncogene Proteins, Viral/genetics ; Oncogene Proteins, Viral/metabolism ; Papillomavirus Infections/enzymology ; Papillomavirus Infections/genetics ; Papillomavirus Infections/virology ; Repressor Proteins/genetics ; Repressor Proteins/metabolism ; Transcriptome ; Tumor Suppressor Protein p53/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Hypoxic repression of pyruvate dehydrogenase activity is necessary for metabolic reprogramming and growth of model tumours.
Autorzy:
Golias T; Institute of Virology, Biomedical Research Center, Slovak Academy of Sciences, Bratislava, 84505, Slovak Republic.
Papandreou I; Department of Radiation Oncology, Ohio State University Comprehensive Cancer Center and Wexner Medical Center, Columbus OH 43210, USA.
Sun R; Department of Radiation Oncology, Ohio State University Comprehensive Cancer Center and Wexner Medical Center, Columbus OH 43210, USA.
Kumar B; Department of Otolaryngology, Ohio State University Comprehensive Cancer Center and Wexner Medical Center, Columbus OH 43210, USA.
Brown NV; Department of Biomedical Informatics, Center for Biostatistics, Ohio State University Comprehensive Cancer Center and Wexner Medical Center, Columbus OH 43210, USA.
Swanson BJ; Department of Pathology, Ohio State University Comprehensive Cancer Center and Wexner Medical Center, Columbus OH 43210, USA.
Pai R; Department of Pathology, University of Pittsburg, Pittsburg PA 15213, USA.
Jaitin D; Department of Immunology, Weizmann Institute of Science, Rehovot, Israel.
Le QT; Department of Radiation Oncology, Stanford University School of Medicine, Stanford CA 94305, USA.
Teknos TN; Department of Otolaryngology, Ohio State University Comprehensive Cancer Center and Wexner Medical Center, Columbus OH 43210, USA.
Denko NC; Department of Radiation Oncology, Ohio State University Comprehensive Cancer Center and Wexner Medical Center, Columbus OH 43210, USA.
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Źródło:
Scientific reports [Sci Rep] 2016 Aug 08; Vol. 6, pp. 31146. Date of Electronic Publication: 2016 Aug 08.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Neoplasm Proteins/*metabolism
Neoplasms, Experimental/*enzymology
Pancreatic Neoplasms/*enzymology
Pyruvate Dehydrogenase Complex/*metabolism
Animals ; Cell Hypoxia ; Cell Line, Tumor ; Female ; Humans ; Mice ; Mice, Nude ; Neoplasms, Experimental/pathology ; Pancreatic Neoplasms/pathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Wyświetlanie 1-20 z 34

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