Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Wyszukujesz frazę ""Telomere Homeostasis"" wg kryterium: Temat


Tytuł:
Telomere Checkpoint in Development and Aging.
Autorzy:
Kalmykova A; Koltzov Institute of Developmental Biology, Russian Academy of Sciences, 119334 Moscow, Russia.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Nov 05; Vol. 24 (21). Date of Electronic Publication: 2023 Nov 05.
Typ publikacji:
Journal Article; Review
MeSH Terms:
RNA*/metabolism
Telomere Homeostasis*
Animals ; Drosophila/genetics ; Aging/genetics ; Telomere/genetics ; Genomic Instability
Czasopismo naukowe
Tytuł:
A comparison of feature selection methodologies and learning algorithms in the development of a DNA methylation-based telomere length estimator.
Autorzy:
Doherty T; School of Biological, Health and Sports Sciences, Technological University Dublin, Dublin, Ireland. .; SFI Centre for Research Training in Machine Learning, Technological University Dublin, Dublin, Ireland. .
Dempster E; University of Exeter Medical School, University of Exeter, Exeter, UK.
Hannon E; University of Exeter Medical School, University of Exeter, Exeter, UK.
Mill J; University of Exeter Medical School, University of Exeter, Exeter, UK.
Poulton R; Department of Psychology, University of Otago, Dunedin, 9016, New Zealand.
Corcoran D; Center for Genomic and Computational Biology, Duke University, Durham, NC, 27708, USA.
Sugden K; Department of Psychology and Neuroscience, Duke University, Durham, NC, USA.
Williams B; Department of Psychology and Neuroscience, Duke University, Durham, NC, USA.
Caspi A; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; Department of Psychology and Neuroscience, Duke University, Durham, NC, USA.
Moffitt TE; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; Department of Psychology and Neuroscience, Duke University, Durham, NC, USA.
Delany SJ; School of Computer Science, Technological University Dublin, Dublin, Ireland.
Murphy TM; School of Biological, Health and Sports Sciences, Technological University Dublin, Dublin, Ireland.
Pokaż więcej
Źródło:
BMC bioinformatics [BMC Bioinformatics] 2023 May 01; Vol. 24 (1), pp. 178. Date of Electronic Publication: 2023 May 01.
Typ publikacji:
Journal Article
MeSH Terms:
Telomere Homeostasis*
DNA Methylation*
Epigenomics*/methods
Algorithms ; Regression Analysis ; Machine Learning ; Humans
Czasopismo naukowe
Tytuł:
TPP1 promoter mutations cooperate with TERT promoter mutations to lengthen telomeres in melanoma.
Autorzy:
Chun-On P; Dorothy P. and Richard P. Simmons Center for Interstitial Lung Disease, Division of Pulmonary, Allergy, and Critical Care Medicine, Pittsburgh, PA, USA.; Environmental and Occupational Health Department, School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA.; Faculty of Medicine and Public Health, Princess Srisavangavadhana College of Medicine, Chulabhorn Royal Academy, Bangkok, Thailand.
Hinchie AM; Dorothy P. and Richard P. Simmons Center for Interstitial Lung Disease, Division of Pulmonary, Allergy, and Critical Care Medicine, Pittsburgh, PA, USA.
Beale HC; UC Santa Cruz Genomics Institute, University of California, Santa Cruz, CA, USA.; Department of Molecular, Cell and Developmental Biology, University of California, Santa Cruz, CA, USA.
Gil Silva AA; Dorothy P. and Richard P. Simmons Center for Interstitial Lung Disease, Division of Pulmonary, Allergy, and Critical Care Medicine, Pittsburgh, PA, USA.
Rush E; University of Pittsburgh Medical Center, Hillman Cancer Institute, Pittsburgh, PA, USA.
Sander C; University of Pittsburgh Medical Center, Hillman Cancer Institute, Pittsburgh, PA, USA.
Connelly CJ; Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Seynnaeve BKN; University of Pittsburgh Medical Center, Hillman Cancer Institute, Pittsburgh, PA, USA.; Department of Pediatrics, Division of Pediatric Hematology/Oncology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Kirkwood JM; University of Pittsburgh Medical Center, Hillman Cancer Institute, Pittsburgh, PA, USA.
Vaske OM; UC Santa Cruz Genomics Institute, University of California, Santa Cruz, CA, USA.; Department of Molecular, Cell and Developmental Biology, University of California, Santa Cruz, CA, USA.
Greider CW; UC Santa Cruz Genomics Institute, University of California, Santa Cruz, CA, USA.; Department of Molecular, Cell and Developmental Biology, University of California, Santa Cruz, CA, USA.; Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Alder JK; Dorothy P. and Richard P. Simmons Center for Interstitial Lung Disease, Division of Pulmonary, Allergy, and Critical Care Medicine, Pittsburgh, PA, USA.
Pokaż więcej
Źródło:
Science (New York, N.Y.) [Science] 2022 Nov 11; Vol. 378 (6620), pp. 664-668. Date of Electronic Publication: 2022 Nov 10.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Melanoma*/genetics
Promoter Regions, Genetic*/genetics
Shelterin Complex*/genetics
Skin Neoplasms*/genetics
Telomerase*/genetics
Telomere Homeostasis*/genetics
Telomere-Binding Proteins*/genetics
Humans ; Cell Line, Tumor ; Gene Expression Regulation, Neoplastic ; Mutation ; Telomere/genetics ; Telomere/metabolism ; Transcriptional Activation
Czasopismo naukowe
Tytuł:
Comparative Application of Terminal Restriction Fragment Analysis Tools to Large-Scale Genomic Assays.
Autorzy:
Abdulkina LR; Institute of Fundamental Medicine and Biology, Kazan Federal University, Kazan 420008, Republic of Tatarstan, Russia.
Agabekian IA; Institute of Fundamental Medicine and Biology, Kazan Federal University, Kazan 420008, Republic of Tatarstan, Russia.
Valeeva LR; Institute of Fundamental Medicine and Biology, Kazan Federal University, Kazan 420008, Republic of Tatarstan, Russia.; Department of Biological Sciences, College of Science, Marshall University, Huntington, WV 25701, USA.
Kozlova OS; Institute of Fundamental Medicine and Biology, Kazan Federal University, Kazan 420008, Republic of Tatarstan, Russia.
Sharipova MR; Institute of Fundamental Medicine and Biology, Kazan Federal University, Kazan 420008, Republic of Tatarstan, Russia.
Shakirov EV; Department of Biological Sciences, College of Science, Marshall University, Huntington, WV 25701, USA.; Department of Biomedical Sciences, Joan C. Edwards School of Medicine, Marshall University, Huntington, WV 25755, USA.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Dec 06; Vol. 24 (24). Date of Electronic Publication: 2023 Dec 06.
Typ publikacji:
Journal Article
MeSH Terms:
Genome-Wide Association Study*
Telomerase*/metabolism
Telomere/genetics ; Telomere/metabolism ; Telomere Homeostasis ; Blotting, Southern ; Genomics
Czasopismo naukowe
Tytuł:
The Altered Functions of Shelterin Components in ALT Cells.
Autorzy:
Zhang Y; Laboratory of Molecular Genetics of Aging and Tumor, Medical School, Kunming University of Science and Technology, 727 Jing Ming Nan Road, Kunming 650500, China.
Hou K; Laboratory of Molecular Genetics of Aging and Tumor, Medical School, Kunming University of Science and Technology, 727 Jing Ming Nan Road, Kunming 650500, China.
Tong J; Laboratory of Molecular Genetics of Aging and Tumor, Medical School, Kunming University of Science and Technology, 727 Jing Ming Nan Road, Kunming 650500, China.
Zhang H; Laboratory of Molecular Genetics of Aging and Tumor, Medical School, Kunming University of Science and Technology, 727 Jing Ming Nan Road, Kunming 650500, China.
Xiong M; Laboratory of Molecular Genetics of Aging and Tumor, Medical School, Kunming University of Science and Technology, 727 Jing Ming Nan Road, Kunming 650500, China.
Liu J; Laboratory of Molecular Genetics of Aging and Tumor, Medical School, Kunming University of Science and Technology, 727 Jing Ming Nan Road, Kunming 650500, China.
Jia S; Laboratory of Molecular Genetics of Aging and Tumor, Medical School, Kunming University of Science and Technology, 727 Jing Ming Nan Road, Kunming 650500, China.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Nov 27; Vol. 24 (23). Date of Electronic Publication: 2023 Nov 27.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Telomere-Binding Proteins*/metabolism
Telomerase*/metabolism
Shelterin Complex ; Telomere/genetics ; Telomere/metabolism ; Telomere Homeostasis ; Telomeric Repeat Binding Protein 2
Czasopismo naukowe
Tytuł:
Novel, clinically relevant genomic patterns identified by comprehensive genomic profiling in ATRX-deficient IDH-wildtype adult high-grade gliomas.
Autorzy:
Bedics G; Department of Pathology and Experimental Cancer Research, Semmelweis University, Üllői út 26, Budapest, 1085, Hungary.; HCEMM-SE Molecular Oncohematology Research Group, Department of Pathology and Experimental Cancer Research, Semmelweis University, Üllői út 26, Budapest, 1085, Hungary.
Szőke P; Department of Pathology and Experimental Cancer Research, Semmelweis University, Üllői út 26, Budapest, 1085, Hungary.
Bátai B; Department of Pathology and Experimental Cancer Research, Semmelweis University, Üllői út 26, Budapest, 1085, Hungary.; HCEMM-SE Molecular Oncohematology Research Group, Department of Pathology and Experimental Cancer Research, Semmelweis University, Üllői út 26, Budapest, 1085, Hungary.
Nagy T; Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Debrecen, Egyetem tér 1, Life Science Building, Debrecen, 4032, Hungary.
Papp G; Department of Pathology and Experimental Cancer Research, Semmelweis University, Üllői út 26, Budapest, 1085, Hungary.
Kránitz N; Department of Pathology, County Hospital Győr, Petz Aladár Hospital, Vasvári Pál út 2-4, Győr, 9024, Hungary.
Rajnai H; Department of Pathology and Experimental Cancer Research, Semmelweis University, Üllői út 26, Budapest, 1085, Hungary.
Reiniger L; Department of Pathology and Experimental Cancer Research, Semmelweis University, Üllői út 26, Budapest, 1085, Hungary.
Bödör C; Department of Pathology and Experimental Cancer Research, Semmelweis University, Üllői út 26, Budapest, 1085, Hungary.; HCEMM-SE Molecular Oncohematology Research Group, Department of Pathology and Experimental Cancer Research, Semmelweis University, Üllői út 26, Budapest, 1085, Hungary.
Scheich B; Department of Pathology and Experimental Cancer Research, Semmelweis University, Üllői út 26, Budapest, 1085, Hungary. .
Pokaż więcej
Źródło:
Scientific reports [Sci Rep] 2023 Oct 27; Vol. 13 (1), pp. 18436. Date of Electronic Publication: 2023 Oct 27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Glioma*/genetics
Glioma*/pathology
Brain Neoplasms*/pathology
Glioblastoma*/pathology
Adult ; Humans ; Telomere Homeostasis ; Mutation ; Genomics ; Isocitrate Dehydrogenase/genetics ; Isocitrate Dehydrogenase/metabolism ; X-linked Nuclear Protein/genetics
Czasopismo naukowe
Tytuł:
UBQLN1 deficiency mediates telomere shortening and IPF through interacting with RPA1.
Autorzy:
Zhou H; MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, China.; Department of Cardiology, Guangdong Provincial Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, China.
Xie C; Cardiovascular Department, The Eighth Affiliated Hospital, Sun Yat-sen University, Shenzhen, China.
Xie Y; MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, China.
He Y; Center for Translational Medicine, Precision Medicine Institute, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Chen Y; Cardiovascular Department, The Eighth Affiliated Hospital, Sun Yat-sen University, Shenzhen, China.
Zhang C; Center for Translational Medicine, Precision Medicine Institute, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Zhang Y; MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, China.
Zhao Y; MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, China.
Liu H; MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, China.
Pokaż więcej
Źródło:
PLoS genetics [PLoS Genet] 2023 Jul 18; Vol. 19 (7), pp. e1010856. Date of Electronic Publication: 2023 Jul 18 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Telomere Shortening*/genetics
Idiopathic Pulmonary Fibrosis*/genetics
Idiopathic Pulmonary Fibrosis*/epidemiology
Idiopathic Pulmonary Fibrosis*/pathology
Humans ; Animals ; Mice ; HeLa Cells ; Telomere Homeostasis ; Telomere/genetics ; Replication Protein A/genetics ; Autophagy-Related Proteins/genetics ; Adaptor Proteins, Signal Transducing/genetics
Czasopismo naukowe
Tytuł:
Methylation of Subtelomeric Chromatin Modifies the Expression of the lncRNA TERRA, Disturbing Telomere Homeostasis.
Autorzy:
Oliva-Rico D; Unidad de Investigación Biomédica en Cáncer, Instituto Nacional de Cancerología (INCan)-Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México (UNAM), Mexico City 14080, Mexico.
Fabian-Morales E; Unidad de Investigación Biomédica en Cáncer, Instituto Nacional de Cancerología (INCan)-Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México (UNAM), Mexico City 14080, Mexico.
Cáceres-Gutiérrez RE; Unidad de Investigación Biomédica en Cáncer, Instituto Nacional de Cancerología (INCan)-Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México (UNAM), Mexico City 14080, Mexico.
Gudiño A; Unidad de Investigación Biomédica en Cáncer, Instituto Nacional de Cancerología (INCan)-Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México (UNAM), Mexico City 14080, Mexico.
Cisneros-Soberanis F; Wellcome Centre for Cell Biology, Institute of Cell Biology (ICB), University of Edinburgh, Edinburgh EH9 3BF, UK.
Dominguez J; Unidad de Investigación Biomédica en Cáncer, Instituto Nacional de Cancerología (INCan)-Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México (UNAM), Mexico City 14080, Mexico.
Almaraz-Rojas O; Instituto Nacional de Medicina Genómica, Mexico City 14610, Mexico.
Arriaga-Canon C; Unidad de Investigación Biomédica en Cáncer, Instituto Nacional de Cancerología (INCan)-Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México (UNAM), Mexico City 14080, Mexico.
Castro-Hernández C; Unidad de Investigación Biomédica en Cáncer, Instituto Nacional de Cancerología (INCan)-Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México (UNAM), Mexico City 14080, Mexico.; Departamento de Medicina Genómica y Toxicología Ambiental, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Ciudad Universitaria, Mexico City 04510, Mexico.
De la Rosa C; Departamento de Biología Molecular de Plantas, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca 62210, Mexico.
Reyes JL; Departamento de Biología Molecular de Plantas, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca 62210, Mexico.
Herrera LA; Unidad de Investigación Biomédica en Cáncer, Instituto Nacional de Cancerología (INCan)-Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México (UNAM), Mexico City 14080, Mexico.; Instituto Nacional de Medicina Genómica, Mexico City 14610, Mexico.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Mar 18; Vol. 23 (6). Date of Electronic Publication: 2022 Mar 18.
Typ publikacji:
Journal Article
MeSH Terms:
RNA, Long Noncoding*/genetics
RNA, Long Noncoding*/metabolism
Telomere Homeostasis*
Chromatin/genetics ; Heterochromatin ; Methylation ; Telomere/genetics ; Telomere/metabolism
Czasopismo naukowe
Tytuł:
Peripheral mitochondrial DNA, telomere length and DNA methylation as predictors of live birth in in vitro fertilization cycles.
Autorzy:
Li Piani L; Dept of Clinical Sciences and Community Health, Università degli Studi di Milano, Milan, Italy.; Infertility Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Reschini M; Infertility Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Somigliana E; Dept of Clinical Sciences and Community Health, Università degli Studi di Milano, Milan, Italy.; Infertility Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Ferrari S; Infertility Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Busnelli A; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy.; Division of Gynecology and Reproductive Medicine, Department of Gynecology, IRCCS Humanitas Research Hospital, Fertility Center, Rozzano, Milan, Italy.
Viganò P; Infertility Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Favero C; Dept of Clinical Sciences and Community Health, Università degli Studi di Milano, Milan, Italy.
Albetti B; Dept of Clinical Sciences and Community Health, Università degli Studi di Milano, Milan, Italy.
Hoxha M; Dept of Clinical Sciences and Community Health, Università degli Studi di Milano, Milan, Italy.
Bollati V; Dept of Clinical Sciences and Community Health, Università degli Studi di Milano, Milan, Italy.
Pokaż więcej
Źródło:
PloS one [PLoS One] 2022 Jan 24; Vol. 17 (1), pp. e0261591. Date of Electronic Publication: 2022 Jan 24 (Print Publication: 2022).
Typ publikacji:
Journal Article
MeSH Terms:
DNA Methylation*
Telomere Homeostasis*
DNA, Mitochondrial/*genetics
Mitochondria/*genetics
Adult ; Birth Rate ; Epigenesis, Genetic ; Female ; Fertilization in Vitro ; Humans ; Italy ; Long Interspersed Nucleotide Elements ; Maternal Age ; Pregnancy ; Pregnancy Rate ; Prospective Studies
Czasopismo naukowe
Tytuł:
Influence of Age and Breed on Bovine Ovarian Capillary Blood Supply, Ovarian Mitochondria and Telomere Length.
Autorzy:
Kordowitzki P; Department of Immunology and Pathology of Reproduction, Institute of Animal Reproduction and Food Research of Polish Academy of Sciences, 10-748 Olsztyn, Poland.; Department of Basic and Preclinical Sciences, Institute for Veterinary Medicine, Nicolaus Copernicus University, 87-100 Torun, Poland.
Merle R; Department of Veterinary Medicine, Institute for Veterinary Epidemiology and Biostatistics, Freie Universität Berlin, 14195 Berlin, Germany.
Hass PK; Department of Veterinary Medicine, Institute of Veterinary Anatomy, Freie Universität Berlin, 14195 Berlin, Germany.
Plendl J; Department of Veterinary Medicine, Institute of Veterinary Anatomy, Freie Universität Berlin, 14195 Berlin, Germany.
Rieger J; Department of Veterinary Medicine, Institute of Veterinary Anatomy, Freie Universität Berlin, 14195 Berlin, Germany.; Division of Veterinary Anatomy, Vetsuisse Faculty, University of Bern, 3012 Bern, Switzerland.
Kaessmeyer S; Department of Veterinary Medicine, Institute of Veterinary Anatomy, Freie Universität Berlin, 14195 Berlin, Germany.; Division of Veterinary Anatomy, Vetsuisse Faculty, University of Bern, 3012 Bern, Switzerland.
Pokaż więcej
Źródło:
Cells [Cells] 2021 Oct 05; Vol. 10 (10). Date of Electronic Publication: 2021 Oct 05.
Typ publikacji:
Journal Article
MeSH Terms:
Breeding*
Telomere Homeostasis*
Aging/*physiology
Capillaries/*physiology
Mitochondria/*metabolism
Ovary/*blood supply
Animals ; Cattle ; Female ; Leukocytes, Mononuclear/metabolism ; Mitochondria/ultrastructure ; Organ Size ; Ovarian Follicle/blood supply ; Ovarian Follicle/ultrastructure ; Ovary/ultrastructure
Czasopismo naukowe
Tytuł:
Association between telomere length and hepatic fibrosis in non-alcoholic fatty liver disease.
Autorzy:
Shin HK; Department of Internal Medicine, Inha University Hospital, Inha University School Medicine, Inchon, South Korea.
Park JH; Department of Pathology, Seoul National University College of Medicine, Seoul Metropolitan Government Boramae Medical Center, Seoul, Korea.
Yu JH; Department of Internal Medicine, Inha University Hospital, Inha University School Medicine, Inchon, South Korea. .
Jin YJ; Department of Internal Medicine, Inha University Hospital, Inha University School Medicine, Inchon, South Korea.
Suh YJ; Department of Biomedical Sciences, College of Medicine, Inha University, Inchon, South Korea.
Lee JW; Department of Internal Medicine, Inha University Hospital, Inha University School Medicine, Inchon, South Korea.
Kim W; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Seoul National University College of Medicine, Seoul Metropolitan Government Boramae Medical Center, Seoul, Korea. .
Pokaż więcej
Corporate Authors:
Korean Nonalcoholic Fatty Liver Study Group (KNSG)
Źródło:
Scientific reports [Sci Rep] 2021 Sep 09; Vol. 11 (1), pp. 18004. Date of Electronic Publication: 2021 Sep 09.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Telomere Homeostasis*
Liver Cirrhosis/*genetics
Non-alcoholic Fatty Liver Disease/*genetics
Telomere/*chemistry
Adult ; Age Factors ; Aged ; Alanine Transaminase/blood ; Alkaline Phosphatase/blood ; Aspartate Aminotransferases/blood ; Cholesterol, HDL/blood ; Cross-Sectional Studies ; Female ; Humans ; Liver/metabolism ; Liver/pathology ; Liver Cirrhosis/blood ; Liver Cirrhosis/diagnosis ; Liver Cirrhosis/pathology ; Logistic Models ; Male ; Middle Aged ; Non-alcoholic Fatty Liver Disease/blood ; Non-alcoholic Fatty Liver Disease/diagnosis ; Non-alcoholic Fatty Liver Disease/pathology ; Odds Ratio ; Severity of Illness Index ; gamma-Glutamyltransferase/blood
Czasopismo naukowe
Tytuł:
Coming up short: Comparing venous blood, dried blood spots & saliva samples for measuring telomere length in health equity research.
Autorzy:
Geronimus AT; School of Public Health, University of Michigan, Ann Arbor, Michigan, United States of America.; Population Studies Center, Institute for Social Research, University of Michigan, Ann Arbor, Michigan, United States of America.; National Academy of Medicine, Washington, DC, United States of America.
Bound J; Population Studies Center, Institute for Social Research, University of Michigan, Ann Arbor, Michigan, United States of America.; Department of Economics, University of Michigan, Ann Arbor, Michigan, United States of America.
Mitchell C; Population Studies Center, Institute for Social Research, University of Michigan, Ann Arbor, Michigan, United States of America.
Martinez-Cardoso A; Department of Public Health Sciences, University of Chicago, Chicago, Illinois, United States of America.
Evans L; Center for Health Equity Research, Northern Arizona University, Flagstaff, Arizona, United States of America.
Hughes L; School of Public Health, University of Michigan, Ann Arbor, Michigan, United States of America.; Population Studies Center, Institute for Social Research, University of Michigan, Ann Arbor, Michigan, United States of America.
Schneper L; Department of Molecular Biology, Princeton University, Princeton, New Jersey, United States of America.
Notterman DA; Department of Molecular Biology, Princeton University, Princeton, New Jersey, United States of America.
Pokaż więcej
Źródło:
PloS one [PLoS One] 2021 Aug 18; Vol. 16 (8), pp. e0255237. Date of Electronic Publication: 2021 Aug 18 (Print Publication: 2021).
Typ publikacji:
Comparative Study; Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Health Equity*
Research*
Telomere Homeostasis*
Dried Blood Spot Testing/*methods
Saliva/*metabolism
Adult ; Humans ; Leukocytes, Mononuclear/metabolism ; Michigan ; Middle Aged
Czasopismo naukowe
Tytuł:
Association of accelerated dynamics of telomere sequence loss in peripheral blood leukocytes with incident knee osteoarthritis in Osteoarthritis Initiative cohort.
Autorzy:
Guillén R; Genetics Unit, INIBIC-Complexo Hospitalario Universitario A Coruña (CHUAC), A Coruña, Spain.; Laboratory of Genetics and Radiobiology, Centro Oncológico de Galicia, A Coruña, Spain.
Otero F; Genetics Unit, INIBIC-Complexo Hospitalario Universitario A Coruña (CHUAC), A Coruña, Spain.; Laboratory of Genetics and Radiobiology, Centro Oncológico de Galicia, A Coruña, Spain.
Mosquera A; Genetics Unit, INIBIC-Complexo Hospitalario Universitario A Coruña (CHUAC), A Coruña, Spain.
Vázquez-Mosquera M; Rheumatology Division, INIBIC-Complexo Hospitalario Universitario A Coruña (CHUAC), A Coruña, Spain.
Rego-Pérez I; Rheumatology Division, INIBIC-Complexo Hospitalario Universitario A Coruña (CHUAC), A Coruña, Spain.
Blanco FJ; Rheumatology Division, INIBIC-Complexo Hospitalario Universitario A Coruña (CHUAC), A Coruña, Spain. .; Department of Physiotherapy, Medicine and Biomedical Sciences, Strategic Group CICA-INIBIC, Rheumatology and Health Group, Universidad de A Coruña, A Coruña, Spain. .; Rheumatology Division, Complexo Hospitalario Universitario A Coruña (CHUAC), As Xubias, 84, 15006, A Coruña, Spain. .
Fernández JL; Genetics Unit, INIBIC-Complexo Hospitalario Universitario A Coruña (CHUAC), A Coruña, Spain.; Laboratory of Genetics and Radiobiology, Centro Oncológico de Galicia, A Coruña, Spain.
Pokaż więcej
Źródło:
Scientific reports [Sci Rep] 2021 Aug 05; Vol. 11 (1), pp. 15914. Date of Electronic Publication: 2021 Aug 05.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Osteoarthritis, Knee/*genetics
Telomere/*pathology
Telomere Homeostasis/*physiology
Aging ; Cohort Studies ; Follow-Up Studies ; Humans ; Incidence ; Knee Joint/pathology ; Leukocytes/pathology ; Leukocytes, Mononuclear/pathology ; Osteoarthritis/genetics ; Osteoarthritis/metabolism ; Osteoarthritis/pathology ; Osteoarthritis, Knee/metabolism ; Osteoarthritis, Knee/pathology ; Prospective Studies ; Risk Factors ; Telomere/metabolism ; Telomere/physiology ; Telomere Homeostasis/genetics
Czasopismo naukowe
Tytuł:
Telomere length and outcome of treatment for pulmonary tuberculosis in a gold mining community.
Autorzy:
Katoto PDMC; Department of Public Health and Primary Care, Centre for Environment and Health, KU Leuven, Leuven, Belgium. .; Department of Internal Medicine, Division of Respiratory Medicine, CEGEMI and Prof. Lurhuma Biomedical Research Laboratory, Mycobacterium Unit, Catholic University of Bukavu, Bukavu, Democratic Republic of Congo. .; Department of Medicine and Center for Infectious Diseases, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa. .
Kayembe-Kitenge T; Department of Public Health and Primary Care, Centre for Environment and Health, KU Leuven, Leuven, Belgium.; Department of Public Health, Unit of Toxicology, University of Lubumbashi, Lubumbashi, Democratic Republic of Congo.
Pollitt KJG; Department of Environmental Health Sciences, School of Public Health, Yale University, New Haven, CT, USA.
Martens DS; Centre of Environmental Health, University of Hasselt, Agoralaan gebouw D, 3590, Diepenbeek, Belgium.
Ghosh M; Department of Public Health and Primary Care, Centre for Environment and Health, KU Leuven, Leuven, Belgium.
Nachega JB; Department of Medicine and Center for Infectious Diseases, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.; Departments of Epidemiology and International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.; Departments of Epidemiology, Infectious Diseases and Microbiology, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA, USA.
Nemery B; Department of Public Health and Primary Care, Centre for Environment and Health, KU Leuven, Leuven, Belgium.
Nawrot TS; Department of Public Health and Primary Care, Centre for Environment and Health, KU Leuven, Leuven, Belgium. .; Centre of Environmental Health, University of Hasselt, Agoralaan gebouw D, 3590, Diepenbeek, Belgium. .
Pokaż więcej
Źródło:
Scientific reports [Sci Rep] 2021 Feb 17; Vol. 11 (1), pp. 4031. Date of Electronic Publication: 2021 Feb 17.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Telomere/*metabolism
Telomere Homeostasis/*physiology
Tuberculosis, Pulmonary/*genetics
Adolescent ; Adult ; Aged ; Biomarkers, Pharmacological/blood ; Child ; Child, Preschool ; DNA, Mitochondrial/analysis ; DNA, Mitochondrial/drug effects ; DNA, Mitochondrial/genetics ; Democratic Republic of the Congo/epidemiology ; Female ; Gold ; Humans ; Male ; Middle Aged ; Miners ; Mining ; Occupational Diseases/etiology ; Proportional Hazards Models ; Prospective Studies ; Telomere/genetics ; Telomere Homeostasis/drug effects ; Telomere Homeostasis/genetics ; Tuberculosis, Pulmonary/therapy
Czasopismo naukowe
Tytuł:
Telomere Length in Chromosomally Normal and Abnormal Miscarriages and Ongoing Pregnancies and Its Association with 5-hydroxymethylcytosine Patterns.
Autorzy:
Krapivin MI; D.O. Ott Research Institute of Obstetrics, Gynecology and Reproductology, Mendeleevskaya Line 3, 199034 Saint Petersburg, Russia.
Tikhonov AV; D.O. Ott Research Institute of Obstetrics, Gynecology and Reproductology, Mendeleevskaya Line 3, 199034 Saint Petersburg, Russia.
Efimova OA; D.O. Ott Research Institute of Obstetrics, Gynecology and Reproductology, Mendeleevskaya Line 3, 199034 Saint Petersburg, Russia.
Pendina AA; D.O. Ott Research Institute of Obstetrics, Gynecology and Reproductology, Mendeleevskaya Line 3, 199034 Saint Petersburg, Russia.
Smirnova AA; Department of Medical Biophysics, Saint Petersburg State Pediatric Medical University, Litovskaya Street 2, 194100 Saint Petersburg, Russia.
Chiryaeva OG; D.O. Ott Research Institute of Obstetrics, Gynecology and Reproductology, Mendeleevskaya Line 3, 199034 Saint Petersburg, Russia.
Talantova OE; D.O. Ott Research Institute of Obstetrics, Gynecology and Reproductology, Mendeleevskaya Line 3, 199034 Saint Petersburg, Russia.
Petrova LI; D.O. Ott Research Institute of Obstetrics, Gynecology and Reproductology, Mendeleevskaya Line 3, 199034 Saint Petersburg, Russia.
Dudkina VS; D.O. Ott Research Institute of Obstetrics, Gynecology and Reproductology, Mendeleevskaya Line 3, 199034 Saint Petersburg, Russia.
Baranov VS; D.O. Ott Research Institute of Obstetrics, Gynecology and Reproductology, Mendeleevskaya Line 3, 199034 Saint Petersburg, Russia.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Jun 21; Vol. 22 (12). Date of Electronic Publication: 2021 Jun 21.
Typ publikacji:
Journal Article
MeSH Terms:
Telomere Homeostasis*
Abortion, Spontaneous/*pathology
Telomere/*pathology
Trophoblasts/*pathology
5-Methylcytosine/analogs & derivatives ; 5-Methylcytosine/metabolism ; Case-Control Studies ; Chorion/pathology ; DNA Methylation ; Female ; Humans ; Lymphocytes/pathology ; Pregnancy ; Pregnancy Trimester, First
Czasopismo naukowe
Tytuł:
Telomere Length in Metaphase Chromosomes of Human Triploid Zygotes.
Autorzy:
Pendina AA; D.O. Ott Research Institute of Obstetrics, Gynecology and Reproductology, Mendeleevskaya Line 3, 199034 Saint Petersburg, Russia.
Krapivin MI; D.O. Ott Research Institute of Obstetrics, Gynecology and Reproductology, Mendeleevskaya Line 3, 199034 Saint Petersburg, Russia.
Efimova OA; D.O. Ott Research Institute of Obstetrics, Gynecology and Reproductology, Mendeleevskaya Line 3, 199034 Saint Petersburg, Russia.
Tikhonov AV; D.O. Ott Research Institute of Obstetrics, Gynecology and Reproductology, Mendeleevskaya Line 3, 199034 Saint Petersburg, Russia.
Mekina ID; D.O. Ott Research Institute of Obstetrics, Gynecology and Reproductology, Mendeleevskaya Line 3, 199034 Saint Petersburg, Russia.
Komarova EM; D.O. Ott Research Institute of Obstetrics, Gynecology and Reproductology, Mendeleevskaya Line 3, 199034 Saint Petersburg, Russia.
Koltsova AS; D.O. Ott Research Institute of Obstetrics, Gynecology and Reproductology, Mendeleevskaya Line 3, 199034 Saint Petersburg, Russia.
Gzgzyan AM; D.O. Ott Research Institute of Obstetrics, Gynecology and Reproductology, Mendeleevskaya Line 3, 199034 Saint Petersburg, Russia.
Kogan IY; D.O. Ott Research Institute of Obstetrics, Gynecology and Reproductology, Mendeleevskaya Line 3, 199034 Saint Petersburg, Russia.
Chiryaeva OG; D.O. Ott Research Institute of Obstetrics, Gynecology and Reproductology, Mendeleevskaya Line 3, 199034 Saint Petersburg, Russia.
Baranov VS; D.O. Ott Research Institute of Obstetrics, Gynecology and Reproductology, Mendeleevskaya Line 3, 199034 Saint Petersburg, Russia.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 May 25; Vol. 22 (11). Date of Electronic Publication: 2021 May 25.
Typ publikacji:
Journal Article
MeSH Terms:
Metaphase*
Telomere Homeostasis*
Triploidy*
Chromosomes, Human/*metabolism
Telomere/*metabolism
Zygote/*metabolism
Fertilization in Vitro ; Humans ; Telomere/pathology ; Zygote/pathology
Czasopismo naukowe
Tytuł:
Low frequency variants associated with leukocyte telomere length in the Singapore Chinese population.
Autorzy:
Chang X; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Khoo Teck Puat-National University Children's Medical Institute, National University Health System, Singapore, Singapore.
Gurung RL; Clinical Research Unit, Khoo Teck Puat Hospital, Singapore, Singapore.
Wang L; Genome Institute of Singapore, Agency for Science, Technology, and Research, Singapore, Singapore.
Jin A; Health Services and Systems Research, Duke-NUS Medical School Singapore, Singapore, Singapore.
Li Z; Genome Institute of Singapore, Agency for Science, Technology, and Research, Singapore, Singapore.
Wang R; Division of Cancer Control and Population Sciences, UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA, USA.
Beckman KB; University of Minnesota Genomics Center, University of Minnesota, Minneapolis, MN, USA.
Adams-Haduch J; Division of Cancer Control and Population Sciences, UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA, USA.
Meah WY; Genome Institute of Singapore, Agency for Science, Technology, and Research, Singapore, Singapore.
Sim KS; Genome Institute of Singapore, Agency for Science, Technology, and Research, Singapore, Singapore.
Lim WK; SingHealth Duke-NUS Institute of Precision Medicine, Singapore, Singapore.; Cancer & Stem Cell Biology Program, Duke-NUS Medical School, Singapore, Singapore.; SingHealth Duke-NUS Genomic Medicine Centre, Singapore, Singapore.
Davila S; SingHealth Duke-NUS Institute of Precision Medicine, Singapore, Singapore.; Cardiovascular and Metabolic Disorders Program, Duke-NUS Medical School, Singapore, Singapore.
Tan P; Genome Institute of Singapore, Agency for Science, Technology, and Research, Singapore, Singapore.; SingHealth Duke-NUS Institute of Precision Medicine, Singapore, Singapore.; Cancer & Stem Cell Biology Program, Duke-NUS Medical School, Singapore, Singapore.; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.
Teo JX; SingHealth Duke-NUS Institute of Precision Medicine, Singapore, Singapore.
Yeo KK; SingHealth Duke-NUS Institute of Precision Medicine, Singapore, Singapore.; Department of Cardiology, National Heart Centre Singapore, Singapore, Singapore.
M Y; Clinical Research Unit, Khoo Teck Puat Hospital, Singapore, Singapore.
Liu S; Clinical Research Unit, Khoo Teck Puat Hospital, Singapore, Singapore.
Lim SC; Clinical Research Unit, Khoo Teck Puat Hospital, Singapore, Singapore.; Diabetes Centre, Admiralty Medical Centre, Singapore, Singapore.; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.
Liu J; Genome Institute of Singapore, Agency for Science, Technology, and Research, Singapore, Singapore.; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
van Dam RM; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Friedlander Y; School of Public Health and Community Medicine, Hebrew University of Jerusalem, Jerusalem, Israel.
Koh WP; Health Services and Systems Research, Duke-NUS Medical School Singapore, Singapore, Singapore.; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.
Yuan JM; Division of Cancer Control and Population Sciences, UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA.
Khor CC; Genome Institute of Singapore, Agency for Science, Technology, and Research, Singapore, Singapore.; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.
Heng CK; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. .; Khoo Teck Puat-National University Children's Medical Institute, National University Health System, Singapore, Singapore. .
Dorajoo R; Genome Institute of Singapore, Agency for Science, Technology, and Research, Singapore, Singapore. .; Health Services and Systems Research, Duke-NUS Medical School Singapore, Singapore, Singapore. .
Pokaż więcej
Źródło:
Communications biology [Commun Biol] 2021 May 03; Vol. 4 (1), pp. 519. Date of Electronic Publication: 2021 May 03.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Polymorphism, Single Nucleotide*
Telomere Homeostasis*
Leukocytes/*pathology
Neoplasms/*epidemiology
Telomere-Binding Proteins/*genetics
Adult ; Aged ; Aged, 80 and over ; Asian People/genetics ; Chronic Disease ; Cross-Sectional Studies ; Female ; Humans ; Leukocytes/metabolism ; Male ; Middle Aged ; Neoplasms/genetics ; Neoplasms/pathology ; Prospective Studies ; Shelterin Complex ; Singapore/epidemiology ; Young Adult
Czasopismo naukowe
Tytuł:
Postnatal Catch-Up Growth Programs Telomere Dynamics and Glucose Intolerance in Low Birth Weight Mice.
Autorzy:
Pericuesta E; Departamento de Reproducción Animal, Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA), 28040 Madrid, Spain.
Gutiérrez-Arroyo JL; Departamento de Reproducción Animal, Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA), 28040 Madrid, Spain.
Sánchez-Calabuig MJ; Departamento de Reproducción Animal, Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA), 28040 Madrid, Spain.
Gutiérrez-Adán A; Departamento de Reproducción Animal, Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA), 28040 Madrid, Spain.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Apr 01; Vol. 22 (7). Date of Electronic Publication: 2021 Apr 01.
Typ publikacji:
Journal Article
MeSH Terms:
Body Weight*
Telomere Homeostasis*
Fetal Growth Retardation/*metabolism
Glucose Intolerance/*etiology
Intercellular Signaling Peptides and Proteins/*metabolism
Animals ; Brain/metabolism ; Disease Models, Animal ; Female ; Fetal Growth Retardation/physiopathology ; Gene Expression Regulation, Developmental ; Liver/metabolism ; Male ; Mice ; Muscles/metabolism
Czasopismo naukowe
Tytuł:
Pol α-primase dependent nuclear localization of the mammalian CST complex.
Autorzy:
Kelich JM; The Wistar Institute, Philadelphia, PA, USA.
Papaioannou H; The Wistar Institute, Philadelphia, PA, USA.
Skordalakes E; The Wistar Institute, Philadelphia, PA, USA. .
Pokaż więcej
Źródło:
Communications biology [Commun Biol] 2021 Mar 17; Vol. 4 (1), pp. 349. Date of Electronic Publication: 2021 Mar 17.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Telomere Homeostasis*
Cell Nucleus/*enzymology
DNA Polymerase I/*metabolism
DNA Primase/*metabolism
Telomere/*metabolism
Telomere-Binding Proteins/*metabolism
Cell Nucleus/genetics ; DNA Polymerase I/genetics ; DNA Primase/genetics ; DNA Replication ; HEK293 Cells ; Humans ; Mitosis ; Multiprotein Complexes ; Mutation ; Protein Binding ; Telomere/genetics ; Telomere-Binding Proteins/genetics
Czasopismo naukowe
Tytuł:
Telomere lengths correlate with fitness but assortative mating by telomeres confers no benefit to fledgling recruitment.
Autorzy:
Young RC; Department of Biological Sciences, North Dakota State University, Stevens Hall 311, Fargo, ND, USA. .; Instituto de Ecología, Universidad Nacional Autónoma de México, Mexico City, Mexico. .
Kitaysky AS; Institute of Arctic Biology & Department of Biology and Wildlife, University of Alaska Fairbanks, 907 Koyukuk Dr, Fairbanks, AK, 99709, USA.
Drummond HM; Instituto de Ecología, Universidad Nacional Autónoma de México, Circuito Exterior S/N Anexo Jardín Botánico Exterior, Ciudad Universitaria, 04500, Mexico City, Mexico.
Pokaż więcej
Źródło:
Scientific reports [Sci Rep] 2021 Mar 09; Vol. 11 (1), pp. 5463. Date of Electronic Publication: 2021 Mar 09.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Telomere Homeostasis*
Birds/*physiology
Animals ; Breeding ; Female ; Longevity ; Male ; Reproduction
Czasopismo naukowe

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies