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Tytuł :
New chromanone derivatives containing thiazoles: Synthesis and antitumor activity evaluation on A549 lung cancer cell line.
Autorzy :
Yurttaş L; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, Eskişehir, Turkey.
Temel HE; Department of Biochemistry, Faculty of Pharmacy, Anadolu University, Eskişehir, Turkey.
Aksoy MO; Department of Biochemistry, Faculty of Pharmacy, Anadolu University, Eskişehir, Turkey.
Bülbül EF; Institute of Pharmacy, Martin Luther University of Halle-Wittenberg, Halle/Saale, Germany.
Çiftçi GA; Department of Biochemistry, Faculty of Pharmacy, Anadolu University, Eskişehir, Turkey.
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Źródło :
Drug development research [Drug Dev Res] 2021 Sep 17. Date of Electronic Publication: 2021 Sep 17.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Apoptotic Effect of Novel Benzimidazole Derivatives Bearing Pyridyl/Pyrimidinyl Piperazine Moiety.
Autorzy :
Çiftçi G; Department of Biochemistry, Faculty of Pharmacy, Anadolu University, 26470 Eskisehir, Turkey.
Temel HE; Department of Biochemistry, Faculty of Pharmacy, Anadolu University, 26470 Eskisehir, Turkey.
Yurttaş L; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, 26470 Eskisehir, Turkey.
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Źródło :
Anti-cancer agents in medicinal chemistry [Anticancer Agents Med Chem] 2021 Jul 07. Date of Electronic Publication: 2021 Jul 07.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Synthesis and Evaluation of a New Series of Thiazolyl-pyrazoline Derivatives as Cholinesterase Inhibitors.
Autorzy :
Temel HE; Anadolu University, Faculty of Pharmacy, Department of Biochemistry, Eskişehir, Turkey.
Altintop MD; Anadolu University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, Eskişehir, Turkey.
Özdemir A; Anadolu University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, Eskişehir, Turkey.
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Źródło :
Turkish journal of pharmaceutical sciences [Turk J Pharm Sci] 2018 Dec; Vol. 15 (3), pp. 333-338. Date of Electronic Publication: 2018 Nov 20.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
New Thiazoline-Tetralin Derivatives and Biological Activity Evaluation.
Autorzy :
Turan-Zitouni G; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, 26470 Eskisehir, Turkey. .
Yurttaş L; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, 26470 Eskisehir, Turkey. .
Tabbi A; Department of Chemistry, Faculty of Sciences, Mentouri University, 25000 Constantin, Algeria. .
Akalın Çiftçi G; Department of Biochemistry, Faculty of Pharmacy, Anadolu University, 26470 Eskisehir, Turkey.
Temel HE; Department of Biochemistry, Faculty of Pharmacy, Anadolu University, 26470 Eskisehir, Turkey. .
Kaplancıklı ZA; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, 26470 Eskisehir, Turkey. .
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2018 Jan 10; Vol. 23 (1). Date of Electronic Publication: 2018 Jan 10.
Typ publikacji :
Evaluation Study; Journal Article
MeSH Terms :
Antineoplastic Agents/*chemistry
Hydrazines/*chemistry
Triazoles/*chemistry
A549 Cells ; Animals ; Antineoplastic Agents/pharmacology ; Apoptosis ; Cell Survival ; Cholinesterase Inhibitors/chemistry ; Cholinesterase Inhibitors/pharmacology ; Cisplatin/chemistry ; Cisplatin/pharmacology ; Drug Screening Assays, Antitumor/methods ; Humans ; Hydrazines/pharmacology ; MCF-7 Cells ; Magnetic Resonance Spectroscopy/methods ; Mass Spectrometry/methods ; Mice ; Molecular Structure ; NIH 3T3 Cells ; Nucleic Acid Synthesis Inhibitors/chemistry ; Nucleic Acid Synthesis Inhibitors/pharmacology ; Structure-Activity Relationship ; Triazoles/pharmacology
Czasopismo naukowe
Tytuł :
Synthesis and Biological Evaluation of New 1,3,4-Oxadiazoles as Potential Anticancer Agents and Enzyme Inhibitors.
Autorzy :
Yurttaş L; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, 26470 Eskisehir, Turkey.
Çavuşoğlu BK; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, 26470 Eskisehir, Turkey.
Çiftçi GA; Department of Biochemistry, Faculty of Pharmacy, Anadolu University, 26470 Eskisehir, Turkey.
Temel HE; Department of Biochemistry, Faculty of Pharmacy, Anadolu University, 26470 Eskisehir, Turkey.
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Źródło :
Anti-cancer agents in medicinal chemistry [Anticancer Agents Med Chem] 2018; Vol. 18 (6), pp. 914-921.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Acetylcholinesterase/*metabolism
Antineoplastic Agents/*pharmacology
Cholinesterase Inhibitors/*pharmacology
Oxadiazoles/*pharmacology
Animals ; Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cholinesterase Inhibitors/chemical synthesis ; Cholinesterase Inhibitors/chemistry ; Dose-Response Relationship, Drug ; Drug Screening Assays, Antitumor ; Humans ; Mice ; Molecular Structure ; NIH 3T3 Cells ; Oxadiazoles/chemical synthesis ; Oxadiazoles/chemistry ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Synthesis and Evaluation of New Oxadiazole, Thiadiazole, and Triazole Derivatives as Potential Anticancer Agents Targeting MMP-9.
Autorzy :
Özdemir A; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, Eskişehir 26470, Turkey. .
Sever B; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, Eskişehir 26470, Turkey. .
Altıntop MD; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, Eskişehir 26470, Turkey. .
Temel HE; Department of Biochemistry, Faculty of Pharmacy, Anadolu University, Eskişehir 26470, Turkey. .
Atlı Ö; Department of Pharmaceutical Toxicology, Faculty of Pharmacy, Anadolu University, Eskişehir 26470, Turkey. .
Baysal M; Department of Pharmaceutical Toxicology, Faculty of Pharmacy, Anadolu University, Eskişehir 26470, Turkey. .
Demirci F; Department of Pharmacognosy, Faculty of Pharmacy, Anadolu University, Eskişehir 26470, Turkey. .
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2017 Jul 04; Vol. 22 (7). Date of Electronic Publication: 2017 Jul 04.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents/*chemical synthesis
Matrix Metalloproteinase 9/*metabolism
Matrix Metalloproteinase Inhibitors/*chemical synthesis
Neoplasms/*metabolism
A549 Cells ; Animals ; Antineoplastic Agents/chemistry ; Antineoplastic Agents/pharmacology ; Catalytic Domain/drug effects ; Cell Line, Tumor ; Cell Movement/drug effects ; Humans ; Matrix Metalloproteinase 9/chemistry ; Matrix Metalloproteinase Inhibitors/chemistry ; Matrix Metalloproteinase Inhibitors/pharmacology ; Mice ; Molecular Docking Simulation ; NIH 3T3 Cells ; Neoplasm Invasiveness ; Neoplasms/drug therapy ; Oxadiazoles/chemical synthesis ; Oxadiazoles/chemistry ; Oxadiazoles/pharmacology ; Rats ; Structure-Activity Relationship ; Thiadiazoles/chemical synthesis ; Thiadiazoles/chemistry ; Thiadiazoles/pharmacology ; Triazoles/chemical synthesis ; Triazoles/chemistry ; Triazoles/pharmacology
Czasopismo naukowe
Tytuł :
Rhanterium epapposum Oliv. essential oil: Chemical composition and antimicrobial, insect-repellent and anticholinesterase activities.
Autorzy :
Demirci B; Anadolu University, Faculty of Pharmacy, Department of Pharmacognosy, 26470 Eskisehir, Turkey.
Yusufoglu HS; Department of Pharmacognosy, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-Kharj, Saudi Arabia.
Tabanca N; Department of Entomology and Nematology, Emerging Pathogens Institute, University of Florida, Gainesville, FL 32610, USA.
Temel HE; Anadolu University, Faculty of Pharmacy, Department of Biochemistry, 26470 Eskisehir, Turkey.
Bernier UR; USDA-ARS, Center for Medical, Agricultural, and Veterinary Entomology, Gainesville, FL 32608, USA.
Agramonte NM; Department of Entomology and Nematology, Emerging Pathogens Institute, University of Florida, Gainesville, FL 32610, USA.
Alqasoumi SI; Department of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Al-Rehaily AJ; Department of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Başer KHC; Anadolu University, Faculty of Pharmacy, Department of Pharmacognosy, 26470 Eskisehir, Turkey.; King Saud University, College of Science, Botany and Microbiology Department, 11451 Riyadh, Saudi Arabia.
Demirci F; Anadolu University, Faculty of Pharmacy, Department of Pharmacognosy, 26470 Eskisehir, Turkey.
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Źródło :
Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society [Saudi Pharm J] 2017 Jul; Vol. 25 (5), pp. 703-708. Date of Electronic Publication: 2016 Nov 01.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Biological Activity Evaluation of Novel 1,2,4-Triazine Derivatives Containing Thiazole/Benzothiazole Rings.
Autorzy :
Yurttas L; Faculty of Pharmacy, Department of Pharmaceutical Chemistry, Anadolu University, 26470 Eskisehir. Turkey.
Ciftci GA; Faculty of Pharmacy, Department of Biohemistry, Anadolu University, 26470 Eskisehir. Turkey.
Temel HE; Faculty of Pharmacy, Department of Biohemistry, Anadolu University, 26470 Eskisehir. Turkey.
Saglik BN; Faculty of Pharmacy, Department of Pharmaceutical Chemistry, Anadolu University, 26470 Eskisehir. Turkey.
Demir B; Faculty of Pharmacy, Department of Pharmaceutical Chemistry, Anadolu University, 26470 Eskisehir. Turkey.
Levent S; Faculty of Pharmacy, Department of Pharmaceutical Chemistry, Anadolu University, 26470 Eskisehir. Turkey.
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Źródło :
Anti-cancer agents in medicinal chemistry [Anticancer Agents Med Chem] 2017; Vol. 17 (13), pp. 1846-1853.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antineoplastic Agents/*pharmacology
Benzothiazoles/*chemistry
Thiazoles/*chemistry
Triazines/*chemistry
Triazines/*pharmacology
Animals ; Apoptosis/drug effects ; Cell Proliferation/drug effects ; Drug Screening Assays, Antitumor ; Humans ; Inhibitory Concentration 50 ; MCF-7 Cells ; Mice ; NIH 3T3 Cells ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Synthesis and Evaluation of A New Series of Thiazole Derivatives as Potential Antitumor Agents and MMP Inhibitors.
Autorzy :
Kaplancikli ZA
Altıntop MD; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, 26470 Eskişehir, Turkey.
Atli O
Sever B
Baysal M
Temel HE
Demirci F; Department of Pharmacognosy, Faculty of Pharmacy, Anadolu University, 26470 Eskisehir, Turkey.
Ozdemir A; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, 26470 Eskişehir, Turkey.
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Źródło :
Anti-cancer agents in medicinal chemistry [Anticancer Agents Med Chem] 2017; Vol. 17 (5), pp. 674-681.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents/*pharmacology
Matrix Metalloproteinase Inhibitors/*pharmacology
Matrix Metalloproteinases/*metabolism
Thiazoles/*pharmacology
Animals ; Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Dose-Response Relationship, Drug ; Drug Screening Assays, Antitumor ; Humans ; Matrix Metalloproteinase Inhibitors/chemical synthesis ; Matrix Metalloproteinase Inhibitors/chemistry ; Mice ; Molecular Structure ; NIH 3T3 Cells ; Structure-Activity Relationship ; Thiazoles/chemical synthesis ; Thiazoles/chemistry
Czasopismo naukowe
Tytuł :
Synthesis and Evaluation of New Benzodioxole- Based Thiosemicarbazone Derivatives as Potential Antitumor Agents.
Autorzy :
Altıntop MD; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, 26470 Eskişehir, Turkey. .
Temel HE; Department of Biochemistry, Faculty of Pharmacy, Anadolu University, 26470 Eskişehir, Turkey. .
Sever B; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, 26470 Eskişehir, Turkey. .
Akalın Çiftçi G; Department of Biochemistry, Faculty of Pharmacy, Anadolu University, 26470 Eskişehir, Turkey. .
Kaplancıklı ZA; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, 26470 Eskişehir, Turkey. .
Pokaż więcej
Źródło :
Molecules (Basel, Switzerland) [Molecules] 2016 Nov 22; Vol. 21 (11). Date of Electronic Publication: 2016 Nov 22.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents/*chemical synthesis
Antineoplastic Agents/*pharmacology
Benzodioxoles/*chemistry
Thiosemicarbazones/*chemical synthesis
Thiosemicarbazones/*pharmacology
A549 Cells ; Animals ; Antineoplastic Agents/chemistry ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Cholinesterase Inhibitors/chemical synthesis ; Cholinesterase Inhibitors/pharmacology ; Dose-Response Relationship, Drug ; Drug Screening Assays, Antitumor ; Humans ; Membrane Potential, Mitochondrial/drug effects ; Mice ; Molecular Docking Simulation ; Molecular Structure ; NIH 3T3 Cells ; Rats ; Structure-Activity Relationship ; Thiosemicarbazones/chemistry
Czasopismo naukowe
Tytuł :
The impact of klotho gene polymorphisms on urinary tract stone disease.
Autorzy :
Gürel A; Department of Urology, Faculty of Medicine, Osmangazi University, Eskisehir, Turkey.
Üre İ; Department of Urology, Faculty of Medicine, Osmangazi University, Eskisehir, Turkey. .
Temel HE; Department of Medical Biochemistry, Faculty of Pharmacy, Anadolu University, Eskisehir, Turkey.
Çilingir O; Department of Medical Genetics, Faculty of Medicine, Osmangazi University, Eskisehir, Turkey.
Uslu S; Department of Medical Biochemistry, Faculty of Medicine, Osmangazi University, Eskisehir, Turkey.
Celayir MF; Department of Urology, Şevket Yılmaz Education and Research Hospital, Bursa, Turkey.
Aslan S; Department of Medical Genetics, Faculty of Medicine, Osmangazi University, Eskisehir, Turkey.
Başeskioğlu AB; Department of Urology, Faculty of Medicine, Osmangazi University, Eskisehir, Turkey.
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Źródło :
World journal of urology [World J Urol] 2016 Jul; Vol. 34 (7), pp. 1045-50. Date of Electronic Publication: 2015 Nov 19.
Typ publikacji :
Journal Article
MeSH Terms :
Polymorphism, Genetic*
Glucuronidase/*genetics
Urinary Calculi/*genetics
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Female ; Glucuronidase/metabolism ; Humans ; Male ; Middle Aged ; Prospective Studies ; Urinary Calculi/enzymology ; Young Adult
Czasopismo naukowe
Tytuł :
Effects of serum uric acid levels on the arginase pathway in women with metabolic syndrome.
Autorzy :
Uslu S; Department of Biochemistry, Medical Faculty, Eskisehir Osmangazi University, Eskisehir, Turkey.
Ozcelik E; Department of Nutrition and Dietetics, School of Healthy, Artvin Coruh University, Artvin, Turkey. .
Kebapci N; Department of Endocrinology, Medical Faculty, Eskisehir Osmangazi University, Eskisehir, Turkey.
Temel HE; Department of Biochemistry, Faculty of Pharmacy, Anadolu University, Eskisehir, Turkey.
Demirci F; Department of Pharmacognosy, Faculty of Pharmacy, Anadolu University, Eskisehir, Turkey.
Ergun B; Department of Toxicology, Faculty of Pharmacy, Anadolu University, Eskisehir, Turkey.
Demirustu C; Department of Biostatistics, Medical Faculty, Eskisehir Osmangazi University, Eskisehir, Turkey.
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Źródło :
Irish journal of medical science [Ir J Med Sci] 2016 Feb; Vol. 185 (1), pp. 259-63. Date of Electronic Publication: 2015 Aug 02.
Typ publikacji :
Journal Article
MeSH Terms :
Arginase/*blood
Metabolic Syndrome/*metabolism
Uric Acid/*blood
Adult ; Blood Glucose/analysis ; Body Mass Index ; Cardiovascular Diseases/metabolism ; Case-Control Studies ; Cholesterol, HDL/blood ; Female ; Humans ; Insulin Resistance ; Metabolic Syndrome/blood ; Middle Aged ; Risk Factors ; Triglycerides/blood
Czasopismo naukowe
Tytuł :
Synthesis and evaluation of bis-thiazole derivatives as new anticancer agents.
Autorzy :
Turan-Zitouni G; Anadolu University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, 26470 Eskişehir, Turkey.
Altıntop MD; Anadolu University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, 26470 Eskişehir, Turkey. Electronic address: .
Özdemir A; Anadolu University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, 26470 Eskişehir, Turkey.
Kaplancıklı ZA; Anadolu University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, 26470 Eskişehir, Turkey.
Çiftçi GA; Anadolu University, Faculty of Pharmacy, Department of Biochemistry, 26470 Eskişehir, Turkey.
Temel HE; Anadolu University, Faculty of Pharmacy, Department of Biochemistry, 26470 Eskişehir, Turkey.
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Źródło :
European journal of medicinal chemistry [Eur J Med Chem] 2016 Jan 01; Vol. 107, pp. 288-94. Date of Electronic Publication: 2015 Nov 05.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents/*chemistry
Antineoplastic Agents/*pharmacology
Thiazoles/*chemistry
Animals ; Butyrylcholinesterase/metabolism ; Cell Line, Tumor ; Chemistry Techniques, Synthetic ; Cholinesterase Inhibitors/chemistry ; Cholinesterase Inhibitors/pharmacology ; DNA/biosynthesis ; Drug Screening Assays, Antitumor/methods ; Humans ; Inhibitory Concentration 50 ; Mice ; NIH 3T3 Cells/drug effects ; Rats ; Thiazoles/pharmacology
Czasopismo naukowe
Tytuł :
Butrylcholinesterase activity in chronic liver disease patients and correlation with Child-Pugh classification and MELD scoring system.
Autorzy :
Temel HE
Temel T
Cansu DU
Ozakyol A
Pokaż więcej
Źródło :
Clinical laboratory [Clin Lab] 2015; Vol. 61 (3-4), pp. 421-6.
Typ publikacji :
Journal Article
MeSH Terms :
Butyrylcholinesterase/*blood
Butyrylcholinesterase/*metabolism
End Stage Liver Disease/*enzymology
Adult ; Biopsy ; Body Mass Index ; Case-Control Studies ; End Stage Liver Disease/classification ; Female ; Healthy Volunteers ; Hepatocytes/enzymology ; Humans ; Liver/enzymology ; Male ; Middle Aged ; Prognosis ; Reproducibility of Results ; Severity of Illness Index ; Time Factors ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Supplemental carvacrol can reduce the severity of inflammation by influencing the production of mediators of inflammation.
Autorzy :
Kara M; Department of Medical Biochemistry, Faculty of Medicine, Eskisehir Osmangazi University, Eskisehir, Turkey, .
Uslu S
Demirci F
Temel HE
Baydemir C
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Źródło :
Inflammation [Inflammation] 2015; Vol. 38 (3), pp. 1020-7.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Inflammatory Agents/*pharmacology
Antioxidants/*pharmacology
Inflammation/*drug therapy
Monoterpenes/*pharmacology
Sepsis/*drug therapy
Animals ; Arginase/metabolism ; Biomarkers ; Cymenes ; Female ; Inflammation Mediators/metabolism ; Interleukin-6/blood ; Lipopolysaccharides ; Malondialdehyde/metabolism ; Nitric Oxide/metabolism ; Rats ; Rats, Sprague-Dawley ; Sepsis/immunology ; Tumor Necrosis Factor-alpha/blood
Czasopismo naukowe
Tytuł :
Serum thrombopoietin levels and its relationship with thrombocytopenia in patients with cirrhosis.
Autorzy :
Temel T; Department of Internal Medicine, Division of Gastroenterology, Faculty of Medicine, Eskisehir Osmangazi University, Eskisehir, Turkey.
Cansu DU; Department of Internal Medicine, Division of Rheumotology, Faculty of Medicine, Eskişehir Osmangazi University, Eskisehir, Turkey.
Temel HE; Biochemistry Department, Pharmacy Faculty, Anadolu University, Eskisehir, Turkey.
Ozakyol AH; Department of Internal Medicine, Division of Gastroenterology, Faculty of Medicine, Eskisehir Osmangazi University, Eskisehir, Turkey.
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Źródło :
Hepatitis monthly [Hepat Mon] 2014 May 05; Vol. 14 (5), pp. e18556. Date of Electronic Publication: 2014 May 05 (Print Publication: 2014).
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Synthesis and biological evaluation of some thiazole derivatives as new cholinesterase inhibitors.
Autorzy :
Turan-Zitouni G; Department of Pharmaceutical Chemistry, Anadolu University, Faculty of Pharmacy, Eskişehir, Turkey.
Ozdemir A
Kaplancikli ZA
Altintop MD
Temel HE
Çiftçi GA
Pokaż więcej
Źródło :
Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2013 Jun; Vol. 28 (3), pp. 509-14. Date of Electronic Publication: 2012 Feb 03.
Typ publikacji :
Journal Article
MeSH Terms :
Cholinesterase Inhibitors/*chemical synthesis
Cholinesterase Inhibitors/*pharmacology
Thiazoles/*chemistry
Acetylcholinesterase/metabolism ; Animals ; Butyrylcholinesterase/metabolism ; Chemistry Techniques, Synthetic ; Cholinesterase Inhibitors/chemistry ; Dose-Response Relationship, Drug ; Drug Evaluation, Preclinical/methods ; Magnetic Resonance Spectroscopy ; Mice ; Molecular Structure ; NIH 3T3 Cells/drug effects ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Synthesis and biological evaluation of some pyrazoline derivatives bearing a dithiocarbamate moiety as new cholinesterase inhibitors.
Autorzy :
Altintop MD; Faculty of Pharmacy, Department of Pharmaceutical Chemistry, Anadolu University, Eskişehir, Turkey. />Özdemir A
Kaplancikli ZA
Turan-Zitouni G
Temel HE
Çiftçi GA
Pokaż więcej
Źródło :
Archiv der Pharmazie [Arch Pharm (Weinheim)] 2013 Mar; Vol. 346 (3), pp. 189-99. Date of Electronic Publication: 2013 Feb 07.
Typ publikacji :
Journal Article
MeSH Terms :
Cholinesterase Inhibitors/*chemical synthesis
Pyrazoles/*chemical synthesis
Thiocarbamates/*chemistry
Acetylcholinesterase/metabolism ; Animals ; Butyrylcholinesterase/metabolism ; Cell Culture Techniques ; Cell Survival/drug effects ; Cholinesterase Inhibitors/adverse effects ; Cholinesterase Inhibitors/chemistry ; Cholinesterase Inhibitors/pharmacology ; Drug Design ; Inhibitory Concentration 50 ; Mice ; Molecular Structure ; NIH 3T3 Cells ; Pyrazoles/adverse effects ; Pyrazoles/chemistry ; Pyrazoles/pharmacology ; Tetrazolium Salts/chemistry ; Thiazoles/chemistry
Czasopismo naukowe
Tytuł :
Effect of αlipoic acid and silymarin on bladder outlet obstruction.
Autorzy :
Yildirim A; Department of Urology, Faculty of Medicine, Osmangazi University; Eskişehir, Turkey.
Başeskioğlu B
Temel HE
Erkasap N
Yenilmez A
Uslu S
Ozer C
Ozkurt M
Dönmez T
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Źródło :
Experimental and therapeutic medicine [Exp Ther Med] 2013 Feb; Vol. 5 (2), pp. 596-602. Date of Electronic Publication: 2012 Nov 23.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Synthesis and anticholinesterase activity and cytotoxicity of novel amide derivatives.
Autorzy :
Altintop MD; Anadolu University, Department of Pharmaceutical Chemistry, Eskişehir, Turkey.
Kaplancikli ZA
Ozdemir A
Turan-Zitouni G
Temel HE
Akalın G
Pokaż więcej
Źródło :
Archiv der Pharmazie [Arch Pharm (Weinheim)] 2012 Feb; Vol. 345 (2), pp. 112-6. Date of Electronic Publication: 2011 Oct 18.
Typ publikacji :
Journal Article
MeSH Terms :
Amides/*chemical synthesis
Cholinesterase Inhibitors/*chemical synthesis
Amides/pharmacology ; Animals ; Cell Survival/drug effects ; Cholinesterase Inhibitors/pharmacology ; Mice ; NIH 3T3 Cells ; Structure-Activity Relationship
Czasopismo naukowe

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