Autor: "Temel HE" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: The effects of captopril and losartan on erythrocyte membrane Na+/K(+)-ATPase activity in experimental diabetes mellitus.
Autorzy:: Temel HE; Department of Biochemistry, Faculty of Pharmacy, University of Anadolu, Eskisehir, Turkey. />Akyuz F; Pokaż więcej
Źródło:: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2007 Apr; Vol. 22 (2), pp. 213-7.
Typ publikacji:: Comparative Study; Journal Article
MeSH Terms:: Angiotensin II Type 1 Receptor Blockers/*pharmacology
Angiotensin-Converting Enzyme Inhibitors/*pharmacology
Captopril/*pharmacology
Diabetes Mellitus, Experimental/*enzymology
Erythrocyte Membrane/*enzymology
Losartan/*pharmacology
Sodium-Potassium-Exchanging ATPase/*antagonists & inhibitors
Animals ; Male ; Rats ; Rats, Wistar

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Skocz do pozycji: 2.

Tytuł:: Oxidative stress-mediated myocardiotoxicity of ciprofloxacin and ofloxacin in juvenile rats.
Autorzy:: Saraçoğlu A; Anadolu University, Faculty of Pharmacy, Department of Pharmaceutical Toxicology, Eskişehir, Turkey. />Temel HE
Ergun B
Colak O; Pokaż więcej
Źródło:: Drug and chemical toxicology [Drug Chem Toxicol] 2009; Vol. 32 (3), pp. 238-42.
Typ publikacji:: Journal Article
MeSH Terms:: Anti-Infective Agents/*toxicity
Ciprofloxacin/*toxicity
Heart/*drug effects
Heart Diseases/*chemically induced
Ofloxacin/*toxicity
Oxidative Stress/*drug effects
Animals ; Biomarkers/blood ; Heart Diseases/metabolism ; Malondialdehyde/metabolism ; Myocardium/metabolism ; Nitric Oxide/metabolism ; Oxidative Stress/physiology ; Rats ; Rats, Sprague-Dawley

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Skocz do pozycji: 3.

Tytuł:: Effects of lipoprotein-associated phospholipase A2 on arginase/nitric oxide pathway in hemodialysis patients.
Autorzy:: Tektaş AK; Department of Medical Biochemistry, School of Medicine, Unıiversity of Eskişehir Osmangazi, Eskişehir, Turkey.
Uslu S
Yalçin AU
Sahin G
Temiz G
Kara M
Temel HE
Demirkan ES
Colak E
Colak O; Pokaż więcej
Źródło:: Renal failure [Ren Fail] 2012; Vol. 34 (6), pp. 738-43. Date of Electronic Publication: 2012 May 14.
Typ publikacji:: Journal Article
MeSH Terms:: Renal Dialysis*
Arginase/*blood
Cardiovascular Diseases/*blood
Nitric Oxide/*blood
Phospholipases A2/*blood
Biomarkers/blood ; Body Mass Index ; C-Reactive Protein/analysis ; Case-Control Studies ; Creatinine/blood ; Female ; Humans ; Lipids/blood ; Male ; Middle Aged ; Nitrites/blood ; Risk Factors ; Serum Albumin/analysis ; Statistics, Nonparametric

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Skocz do pozycji: 4.

Tytuł:: Synthesis and biological evaluation of some thiazole derivatives as new cholinesterase inhibitors.
Autorzy:: Turan-Zitouni G; Department of Pharmaceutical Chemistry, Anadolu University, Faculty of Pharmacy, Eskişehir, Turkey.
Ozdemir A
Kaplancikli ZA
Altintop MD
Temel HE
Çiftçi GA; Pokaż więcej
Źródło:: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2013 Jun; Vol. 28 (3), pp. 509-14. Date of Electronic Publication: 2012 Feb 03.
Typ publikacji:: Journal Article
MeSH Terms:: Cholinesterase Inhibitors/*chemical synthesis
Cholinesterase Inhibitors/*pharmacology
Thiazoles/*chemistry
Acetylcholinesterase/metabolism ; Animals ; Butyrylcholinesterase/metabolism ; Chemistry Techniques, Synthetic ; Cholinesterase Inhibitors/chemistry ; Dose-Response Relationship, Drug ; Drug Evaluation, Preclinical/methods ; Magnetic Resonance Spectroscopy ; Mice ; Molecular Structure ; NIH 3T3 Cells/drug effects ; Structure-Activity Relationship

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Skocz do pozycji: 5.

Tytuł:: Synthesis and Evaluation of New Benzodioxole- Based Thiosemicarbazone Derivatives as Potential Antitumor Agents.
Autorzy:: Altıntop MD; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, 26470 Eskişehir, Turkey. .
Temel HE; Department of Biochemistry, Faculty of Pharmacy, Anadolu University, 26470 Eskişehir, Turkey. .
Sever B; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, 26470 Eskişehir, Turkey. .
Akalın Çiftçi G; Department of Biochemistry, Faculty of Pharmacy, Anadolu University, 26470 Eskişehir, Turkey. .
Kaplancıklı ZA; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, 26470 Eskişehir, Turkey. .; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2016 Nov 22; Vol. 21 (11). Date of Electronic Publication: 2016 Nov 22.
Typ publikacji:: Journal Article
MeSH Terms:: Antineoplastic Agents/*chemical synthesis
Antineoplastic Agents/*pharmacology
Benzodioxoles/*chemistry
Thiosemicarbazones/*chemical synthesis
Thiosemicarbazones/*pharmacology
A549 Cells ; Animals ; Antineoplastic Agents/chemistry ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Cholinesterase Inhibitors/chemical synthesis ; Cholinesterase Inhibitors/pharmacology ; Dose-Response Relationship, Drug ; Drug Screening Assays, Antitumor ; Humans ; Membrane Potential, Mitochondrial/drug effects ; Mice ; Molecular Docking Simulation ; Molecular Structure ; NIH 3T3 Cells ; Rats ; Structure-Activity Relationship ; Thiosemicarbazones/chemistry

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Skocz do pozycji: 6.

Tytuł:: Synthesis and Evaluation of New Oxadiazole, Thiadiazole, and Triazole Derivatives as Potential Anticancer Agents Targeting MMP-9.
Autorzy:: Özdemir A; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, Eskişehir 26470, Turkey. .
Sever B; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, Eskişehir 26470, Turkey. .
Altıntop MD; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, Eskişehir 26470, Turkey. .
Temel HE; Department of Biochemistry, Faculty of Pharmacy, Anadolu University, Eskişehir 26470, Turkey. .
Atlı Ö; Department of Pharmaceutical Toxicology, Faculty of Pharmacy, Anadolu University, Eskişehir 26470, Turkey. .
Baysal M; Department of Pharmaceutical Toxicology, Faculty of Pharmacy, Anadolu University, Eskişehir 26470, Turkey. .
Demirci F; Department of Pharmacognosy, Faculty of Pharmacy, Anadolu University, Eskişehir 26470, Turkey. .; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2017 Jul 04; Vol. 22 (7). Date of Electronic Publication: 2017 Jul 04.
Typ publikacji:: Journal Article
MeSH Terms:: Antineoplastic Agents/*chemical synthesis
Matrix Metalloproteinase 9/*metabolism
Matrix Metalloproteinase Inhibitors/*chemical synthesis
Neoplasms/*metabolism
A549 Cells ; Animals ; Antineoplastic Agents/chemistry ; Antineoplastic Agents/pharmacology ; Catalytic Domain/drug effects ; Cell Line, Tumor ; Cell Movement/drug effects ; Humans ; Matrix Metalloproteinase 9/chemistry ; Matrix Metalloproteinase Inhibitors/chemistry ; Matrix Metalloproteinase Inhibitors/pharmacology ; Mice ; Molecular Docking Simulation ; NIH 3T3 Cells ; Neoplasm Invasiveness ; Neoplasms/drug therapy ; Oxadiazoles/chemical synthesis ; Oxadiazoles/chemistry ; Oxadiazoles/pharmacology ; Rats ; Structure-Activity Relationship ; Thiadiazoles/chemical synthesis ; Thiadiazoles/chemistry ; Thiadiazoles/pharmacology ; Triazoles/chemical synthesis ; Triazoles/chemistry ; Triazoles/pharmacology

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Skocz do pozycji: 7.

Tytuł:: Synthesis and Evaluation of a New Series of Thiazolyl-pyrazoline Derivatives as Cholinesterase Inhibitors.
Autorzy:: Temel HE; Anadolu University, Faculty of Pharmacy, Department of Biochemistry, Eskişehir, Turkey.
Altintop MD; Anadolu University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, Eskişehir, Turkey.
Özdemir A; Anadolu University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, Eskişehir, Turkey.; Pokaż więcej
Źródło:: Turkish journal of pharmaceutical sciences [Turk J Pharm Sci] 2018 Dec; Vol. 15 (3), pp. 333-338. Date of Electronic Publication: 2018 Nov 20.
Typ publikacji:: Journal Article

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Skocz do pozycji: 8.

Tytuł:: Discovery of Small Molecule COX-1 and Akt Inhibitors as Anti-NSCLC Agents Endowed with Anti-Inflammatory Action.
Autorzy:: Altıntop MD; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, 26470 Eskişehir, Turkey.
Akalın Çiftçi G; Department of Biochemistry, Faculty of Pharmacy, Anadolu University, 26470 Eskişehir, Turkey.; Graduate School of Health Sciences, Anadolu University, 26470 Eskişehir, Turkey.
Yılmaz Savaş N; Graduate School of Health Sciences, Anadolu University, 26470 Eskişehir, Turkey.
Ertorun İ; Department of Medical Biochemistry, Faculty of Medicine, Eskisehir Osmangazi University, 26480 Eskişehir, Turkey.
Can B; Department of Medical Biochemistry, Faculty of Medicine, Eskisehir Osmangazi University, 26480 Eskişehir, Turkey.
Sever B; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, 26470 Eskişehir, Turkey.
Temel HE; Department of Biochemistry, Faculty of Pharmacy, Anadolu University, 26470 Eskişehir, Turkey.
Alataş Ö; Department of Medical Biochemistry, Faculty of Medicine, Eskisehir Osmangazi University, 26480 Eskişehir, Turkey.
Özdemir A; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, 26470 Eskişehir, Turkey.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Jan 31; Vol. 24 (3). Date of Electronic Publication: 2023 Jan 31.
Typ publikacji:: Journal Article
MeSH Terms:: Carcinoma, Non-Small-Cell Lung*
Lung Neoplasms*
Humans ; Angiogenesis Inhibitors/pharmacology ; Anti-Inflammatory Agents/pharmacology ; Anti-Inflammatory Agents/therapeutic use ; Anti-Inflammatory Agents, Non-Steroidal/pharmacology ; Cyclooxygenase 2/metabolism ; Cyclooxygenase 2 Inhibitors/pharmacology ; Cyclooxygenase 2 Inhibitors/therapeutic use ; Molecular Docking Simulation ; Molecular Structure ; Proto-Oncogene Proteins c-akt ; Structure-Activity Relationship ; Cyclooxygenase 1/metabolism

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