Repeated episodes of postictal hypoxia are a mechanism for interictal cognitive impairments.
Autorzy:
Villa BR; Cumming School of Medicine, Hotchkiss Brain Institute, University of Calgary, Calgary, AB, T2N 4N1, Canada. .; Department of Cell Biology and Anatomy, University of Calgary, 3330 Hospital Drive NW, Calgary, AB, T2N 4N1, Canada. . Bhatt D; Cumming School of Medicine, Hotchkiss Brain Institute, University of Calgary, Calgary, AB, T2N 4N1, Canada.; Department of Cell Biology and Anatomy, University of Calgary, 3330 Hospital Drive NW, Calgary, AB, T2N 4N1, Canada. Wolff MD; Cumming School of Medicine, Hotchkiss Brain Institute, University of Calgary, Calgary, AB, T2N 4N1, Canada.; Department of Cell Biology and Anatomy, University of Calgary, 3330 Hospital Drive NW, Calgary, AB, T2N 4N1, Canada. Addo-Osafo K; Cumming School of Medicine, Hotchkiss Brain Institute, University of Calgary, Calgary, AB, T2N 4N1, Canada.; Department of Cell Biology and Anatomy, University of Calgary, 3330 Hospital Drive NW, Calgary, AB, T2N 4N1, Canada. Epp JR; Cumming School of Medicine, Hotchkiss Brain Institute, University of Calgary, Calgary, AB, T2N 4N1, Canada.; Department of Cell Biology and Anatomy, University of Calgary, 3330 Hospital Drive NW, Calgary, AB, T2N 4N1, Canada. TeskeyGC; Cumming School of Medicine, Hotchkiss Brain Institute, University of Calgary, Calgary, AB, T2N 4N1, Canada.; Department of Cell Biology and Anatomy, University of Calgary, 3330 Hospital Drive NW, Calgary, AB, T2N 4N1, Canada.; Cumming School of Medicine, Alberta Children's Hospital Research Institute, University of Calgary, Calgary, AB, T2N 4N1, Canada.
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Źródło:
Scientific reports [Sci Rep] 2023 Sep 19; Vol. 13 (1), pp. 15474. Date of Electronic Publication: 2023 Sep 19.
Caffeine exacerbates seizure-induced death via postictal hypoxia.
Autorzy:
George AG; Cumming School of Medicine, Hotchkiss Brain Institute, University of Calgary, Calgary, AB, T2N 4N1, Canada. .; Department of Cell Biology and Anatomy, University of Calgary, Calgary, AB, Canada. .; Department of Clinical Neurosciences, University of Calgary, Calgary, AB, Canada. .; Department of Clinical Neurosciences, Cumming School of Medicine, University of Calgary, 3330 Hospital Drive N.W. Calgary, Alberta, T2N 4N, Canada. . Federico A; Cumming School of Medicine, Hotchkiss Brain Institute, University of Calgary, Calgary, AB, T2N 4N1, Canada.; Department of Clinical Neurosciences, University of Calgary, Calgary, AB, Canada. Gom RC; Cumming School of Medicine, Hotchkiss Brain Institute, University of Calgary, Calgary, AB, T2N 4N1, Canada.; Department of Cell Biology and Anatomy, University of Calgary, Calgary, AB, Canada. Harris SA; Cumming School of Medicine, Hotchkiss Brain Institute, University of Calgary, Calgary, AB, T2N 4N1, Canada.; Department of Cell Biology and Anatomy, University of Calgary, Calgary, AB, Canada.; Alberta Children's Hospital Research Institute, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada. TeskeyGC; Cumming School of Medicine, Hotchkiss Brain Institute, University of Calgary, Calgary, AB, T2N 4N1, Canada.; Department of Cell Biology and Anatomy, University of Calgary, Calgary, AB, Canada.; Alberta Children's Hospital Research Institute, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
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Źródło:
Scientific reports [Sci Rep] 2023 Aug 29; Vol. 13 (1), pp. 14150. Date of Electronic Publication: 2023 Aug 29.
Three dimensional microelectrodes enable high signal and spatial resolution for neural seizure recordings in brain slices and freely behaving animals.
Autorzy:
Wijdenes P; Faculty of Medicine, Hotchkiss Brain Institute, University of Calgary, 2500 University Dr. NW, Calgary, AB, T2N 1N4, Canada.; Biomedical Engineering Graduate Program, University of Calgary, 2500 University Dr. NW, Calgary, AB, T2N 1N4, Canada. Haider K; Faculty of Medicine, Hotchkiss Brain Institute, University of Calgary, 2500 University Dr. NW, Calgary, AB, T2N 1N4, Canada. Gavrilovici C; Alberta Children's Hospital Research Institute, University of Calgary, 2500 University Dr. NW, Calgary, AB, T2N 1N4, Canada. Gunning B; Department of Cell Biology and Anatomy, University of Calgary, 2500 University Dr. NW, Calgary, AB, T2N 1N4, Canada. Wolff MD; Department of Cell Biology and Anatomy, University of Calgary, 2500 University Dr. NW, Calgary, AB, T2N 1N4, Canada. Lijnse T; Department of Electrical and Computer Engineering, University of Calgary, 2500 University Dr. NW, Calgary, AB, T2N 1N4, Canada. Armstrong R; Faculty of Medicine, Hotchkiss Brain Institute, University of Calgary, 2500 University Dr. NW, Calgary, AB, T2N 1N4, Canada. TeskeyGC; Faculty of Medicine, Hotchkiss Brain Institute, University of Calgary, 2500 University Dr. NW, Calgary, AB, T2N 1N4, Canada.; Alberta Children's Hospital Research Institute, University of Calgary, 2500 University Dr. NW, Calgary, AB, T2N 1N4, Canada. Rho JM; Alberta Children's Hospital Research Institute, University of Calgary, 2500 University Dr. NW, Calgary, AB, T2N 1N4, Canada.; Departments of Neurosciences and Pediatrics, University of California San Diego, Rady Children's Hospital, San Diego, CA, USA. Dalton C; Biomedical Engineering Graduate Program, University of Calgary, 2500 University Dr. NW, Calgary, AB, T2N 1N4, Canada.; Department of Electrical and Computer Engineering, University of Calgary, 2500 University Dr. NW, Calgary, AB, T2N 1N4, Canada. Syed NI; Faculty of Medicine, Hotchkiss Brain Institute, University of Calgary, 2500 University Dr. NW, Calgary, AB, T2N 1N4, Canada. .; Alberta Children's Hospital Research Institute, University of Calgary, 2500 University Dr. NW, Calgary, AB, T2N 1N4, Canada. .; Department of Cell Biology and Anatomy, University of Calgary, 2500 University Dr. NW, Calgary, AB, T2N 1N4, Canada. .; Cumming School of Medicine, University of Calgary, 3330-Hospital Drive, NW, Calgary, AB, T2N 4N1, Canada. .
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Źródło:
Scientific reports [Sci Rep] 2021 Nov 09; Vol. 11 (1), pp. 21952. Date of Electronic Publication: 2021 Nov 09.
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