Autor: "Thaiss CA" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Recent developments in the epidemiology and management of tuberculosis – new solutions to old problems?
Autorzy:: Thaiss WM
Thaiss CC
Thaiss CA; Pokaż więcej
Temat:: Infectious and parasitic diseases
RC109-216
Źródło:: Infection and Drug Resistance, Vol 2012, Iss default, Pp 1-8 (2012)
Opis pliku:: electronic resource
Relacje:: http://www.dovepress.com/recent-developments-in-the-epidemiology-and-management-of-tuberculosis-a9019; https://doaj.org/toc/1178-6973
Dostęp URL:: https://doaj.org/article/01ba4a5383f9490e9e8e6f6ed2eb5135 Link otwiera się w nowym oknie

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Skocz do pozycji: 2.

Tytuł:: From mental strain to gut pain: A brain-gut pathway transducing psychological stress to intestinal inflammation.
Autorzy:: Schneider KM; Microbiology Department, Institute for Immunology, and Institute for Diabetes, Obesity and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.; Department of Medicine III, University Hospital RWTH Aachen, Aachen, Germany.
Blank N; Microbiology Department, Institute for Immunology, and Institute for Diabetes, Obesity and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Thaiss CA; Microbiology Department, Institute for Immunology, and Institute for Diabetes, Obesity and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.; Pokaż więcej
Źródło:: Clinical and translational medicine [Clin Transl Med] 2023 Oct; Vol. 13 (10), pp. e1458.
Typ publikacji:: Journal Article
MeSH Terms:: Inflammatory Bowel Diseases*
Humans ; Stress, Psychological/complications ; Stress, Psychological/psychology ; Brain ; Inflammation/metabolism ; Pain

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Skocz do pozycji: 3.

Tytuł:: Microbiome complexity shapes metabolism.
Autorzy:: Litichevskiy L; Microbiology Department, Institute for Immunology, and Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, United States of America.
Thaiss CA; Microbiology Department, Institute for Immunology, and Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, United States of America.; Pokaż więcej
Źródło:: PLoS biology [PLoS Biol] 2022 Sep 21; Vol. 20 (9), pp. e3001793. Date of Electronic Publication: 2022 Sep 21 (Print Publication: 2022).
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Comment
MeSH Terms:: Gastrointestinal Microbiome*
Microbiota*
Animals ; Germ-Free Life ; Mice

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Skocz do pozycji: 4.

Tytuł:: Metabolic control by the microbiome.
Autorzy:: Cox TO; Microbiology Department, Institute for Immunology, and Institute for Diabetes, Obesity & Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Lundgren P; Microbiology Department, Institute for Immunology, and Institute for Diabetes, Obesity & Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Nath K; Microbiology Department, Institute for Immunology, and Institute for Diabetes, Obesity & Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Thaiss CA; Microbiology Department, Institute for Immunology, and Institute for Diabetes, Obesity & Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. thaiss@pennmedicine.upenn.edu.; Pokaż więcej
Źródło:: Genome medicine [Genome Med] 2022 Jul 29; Vol. 14 (1), pp. 80. Date of Electronic Publication: 2022 Jul 29.
Typ publikacji:: Journal Article; Review; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:: Gastrointestinal Microbiome*/physiology
Microbiota*
Humans

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Skocz do pozycji: 5.

Tytuł:: Early prediction of decompensation (EPOD) score: Non-invasive determination of cirrhosis decompensation risk.
Autorzy:: Schneider ARP; Institute of Applied Microbiology - iAMB, Aachen Biology and Biotechnology - ABBt, RWTH Aachen University, Aachen, Germany.; Systems Pharmacology & Medicine, Bayer AG, Leverkusen, Germany.
Schneider CV; Division of Translational Medicine and Human Genetics, The Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.; Department of Genetics, The Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Schneider KM; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.; Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.; Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Baier V; Institute of Applied Microbiology - iAMB, Aachen Biology and Biotechnology - ABBt, RWTH Aachen University, Aachen, Germany.
Schaper S; Systems Pharmacology & Medicine, Bayer AG, Leverkusen, Germany.
Diedrich C; Systems Pharmacology & Medicine, Bayer AG, Leverkusen, Germany.
Coboeken K; Systems Pharmacology & Medicine, Bayer AG, Leverkusen, Germany.
Mayer H; Systems Pharmacology & Medicine, Bayer AG, Leverkusen, Germany.
Gu W; Medical Department I, Frankfurt University Hospital, Leverkusen, Germany.
Trebicka J; Medical Department I, Frankfurt University Hospital, Leverkusen, Germany.; European Foundation for Study of Chronic Liver Failure, Barcelona, Spain.
Blank LM; Institute of Applied Microbiology - iAMB, Aachen Biology and Biotechnology - ABBt, RWTH Aachen University, Aachen, Germany.
Burghaus R; Clinical Pharmacometrics, Bayer AG, Wuppertal, Germany.
Lippert J; Clinical Pharmacometrics, Bayer AG, Wuppertal, Germany.
Rader DJ; Division of Translational Medicine and Human Genetics, The Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.; Department of Genetics, The Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Thaiss CA; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.; Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.; Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Schlender JF; Systems Pharmacology & Medicine, Bayer AG, Leverkusen, Germany.
Trautwein C; Department of Medicine III, University Hospital Aachen, Aachen, Germany.
Kuepfer L; Institute for Systems Medicine, University Hospital RWTH Aachen, Aachen, Germany.; Pokaż więcej
Źródło:: Liver international : official journal of the International Association for the Study of the Liver [Liver Int] 2022 Mar; Vol. 42 (3), pp. 640-650. Date of Electronic Publication: 2022 Feb 03.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Esophageal and Gastric Varices*/diagnosis
Esophageal and Gastric Varices*/etiology
Ascites/etiology ; Gastrointestinal Hemorrhage ; Humans ; Liver Cirrhosis/complications ; Liver Cirrhosis/diagnosis ; Liver Cirrhosis/drug therapy ; Prognosis ; Retrospective Studies ; Severity of Illness Index

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Skocz do pozycji: 6.

Tytuł:: Microbiome dynamics in obesity.
Autorzy:: Thaiss CA; Microbiology Department, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. thaiss@pennmedicine.upenn.edu.; Pokaż więcej
Źródło:: Science (New York, N.Y.) [Science] 2018 Nov 23; Vol. 362 (6417), pp. 903-904.
Typ publikacji:: Journal Article
MeSH Terms:: Circadian Rhythm*
Gastrointestinal Microbiome/*physiology
Intestines/*microbiology
Obesity/*microbiology
Animals ; Humans ; Mice

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Skocz do pozycji: 7.

Tytuł:: Loss of MicroRNA-21 Influences the Gut Microbiota, Causing Reduced Susceptibility in a Murine Model of Colitis.
Autorzy:: Johnston DGW; School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland.; School of Genetics and Microbiology, Moyne Institute of Preventative Medicine, Trinity College Dublin, Dublin, Ireland.
Williams MA; School of Genetics and Microbiology, Moyne Institute of Preventative Medicine, Trinity College Dublin, Dublin, Ireland.
Thaiss CA; Immunology Department, Weizmann Institute of Science, Rehovot, Israel.
Cabrera-Rubio R; Teagasc Food Research Centre, Moorepark, Fermoy, and APC Microbiome Institute, Cork, Ireland.
Raverdeau M; School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland.
McEntee C; School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland.
Cotter PD; Teagasc Food Research Centre, Moorepark, Fermoy, and APC Microbiome Institute, Cork, Ireland.
Elinav E; Immunology Department, Weizmann Institute of Science, Rehovot, Israel.
O'Neill LAJ; School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland.
Corr SC; School of Genetics and Microbiology, Moyne Institute of Preventative Medicine, Trinity College Dublin, Dublin, Ireland.; Pokaż więcej
Źródło:: Journal of Crohn's & colitis [J Crohns Colitis] 2018 Jun 28; Vol. 12 (7), pp. 835-848.
Typ publikacji:: Journal Article
MeSH Terms:: Genetic Predisposition to Disease*
Colitis/*genetics
Colitis/*microbiology
Gastrointestinal Microbiome/*genetics
MicroRNAs/*genetics
Animals ; Anti-Bacterial Agents/pharmacology ; Colitis/chemically induced ; Colitis/pathology ; Dextran Sulfate ; Disease Models, Animal ; Feces/microbiology ; Female ; Gastrointestinal Microbiome/drug effects ; Gene Deletion ; Male ; Mice ; Protective Factors ; RNA, Ribosomal, 16S/analysis

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Skocz do pozycji: 8.

Tytuł:: Hyperglycemia drives intestinal barrier dysfunction and risk for enteric infection.
Autorzy:: Thaiss CA; Department of Immunology, Weizmann Institute of Science, Rehovot, Israel.
Levy M; Department of Immunology, Weizmann Institute of Science, Rehovot, Israel.
Grosheva I; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
Zheng D; Department of Immunology, Weizmann Institute of Science, Rehovot, Israel.
Soffer E; Department of Immunology, Weizmann Institute of Science, Rehovot, Israel.
Blacher E; Department of Immunology, Weizmann Institute of Science, Rehovot, Israel.
Braverman S; Department of Immunology, Weizmann Institute of Science, Rehovot, Israel.
Tengeler AC; Department of Immunology, Weizmann Institute of Science, Rehovot, Israel.
Barak O; Department of Immunology, Weizmann Institute of Science, Rehovot, Israel.; Department of Obstetrics and Gynecology, Kaplan Medical Center, Rehovot, affiliated with the Hebrew University and Hadassah School of Medicine, Jerusalem, Israel.
Elazar M; Department of Immunology, Weizmann Institute of Science, Rehovot, Israel.
Ben-Zeev R; Department of Immunology, Weizmann Institute of Science, Rehovot, Israel.
Lehavi-Regev D; Department of Immunology, Weizmann Institute of Science, Rehovot, Israel.
Katz MN; Department of Immunology, Weizmann Institute of Science, Rehovot, Israel.
Pevsner-Fischer M; Department of Immunology, Weizmann Institute of Science, Rehovot, Israel.
Gertler A; The Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University, Rehovot, Israel.
Halpern Z; Sackler Faculty of Medicine, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.; Research Center for Digestive Tract and Liver Diseases, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.; Digestive Center, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Harmelin A; Department of Veterinary Resources, Weizmann Institute of Science, Rehovot, Israel.
Aamar S; Department of Medicine, Hadassah-Hebrew University Hospital, Jerusalem, Israel.
Serradas P; INSERM Centre de Recherche des Cordeliers, Sorbonne Université, Sorbonne Cités, UPD Univ. Paris 05, CNRS, IHU ICAN, Paris, France.
Grosfeld A; INSERM Centre de Recherche des Cordeliers, Sorbonne Université, Sorbonne Cités, UPD Univ. Paris 05, CNRS, IHU ICAN, Paris, France.
Shapiro H; Department of Immunology, Weizmann Institute of Science, Rehovot, Israel.
Geiger B; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
Elinav E; Department of Immunology, Weizmann Institute of Science, Rehovot, Israel. .; Pokaż więcej
Źródło:: Science (New York, N.Y.) [Science] 2018 Mar 23; Vol. 359 (6382), pp. 1376-1383. Date of Electronic Publication: 2018 Mar 08.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Blood Glucose/*metabolism
Diabetes Mellitus, Experimental/*physiopathology
Escherichia coli Infections/*physiopathology
Hyperglycemia/*physiopathology
Intestinal Diseases/*microbiology
Intestinal Diseases/*physiopathology
Animals ; Caco-2 Cells ; Cellular Reprogramming ; Citrobacter rodentium ; Enteropathogenic Escherichia coli ; Gastrointestinal Microbiome ; Gene Deletion ; Glucose/metabolism ; Glucose/pharmacology ; Glucose Transporter Type 2/genetics ; Humans ; Intestinal Mucosa/microbiology ; Intestinal Mucosa/physiopathology ; Mice ; Mice, Inbred Strains ; Obesity/physiopathology ; Permeability ; Receptors, Leptin/genetics ; Streptozocin

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Skocz do pozycji: 9.

Tytuł:: Ectopic colonization of oral bacteria in the intestine drives T H 1 cell induction and inflammation.
Autorzy:: Atarashi K; Department of Microbiology and Immunology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.; RIKEN Center for Integrative Medical Sciences, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa 230-0045, Japan.
Suda W; Department of Microbiology and Immunology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.; Graduate School of Frontier Sciences, The University of Tokyo, 5-1-5 Kashiwanoha, Kashiwa, Chiba 277-8561, Japan.; Cooperative Major in Advanced Health Science, Graduate School of Advanced Science and Engineering, Waseda University, Tokyo, Japan.
Luo C; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; Center for Computational and Integrative Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.
Kawaguchi T; Department of Microbiology and Immunology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.; RIKEN Center for Integrative Medical Sciences, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa 230-0045, Japan.
Motoo I; RIKEN Center for Integrative Medical Sciences, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa 230-0045, Japan.
Narushima S; RIKEN Center for Integrative Medical Sciences, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa 230-0045, Japan.
Kiguchi Y; Graduate School of Frontier Sciences, The University of Tokyo, 5-1-5 Kashiwanoha, Kashiwa, Chiba 277-8561, Japan.
Yasuma K; Department of Microbiology and Immunology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.
Watanabe E; RIKEN Center for Integrative Medical Sciences, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa 230-0045, Japan.
Tanoue T; Department of Microbiology and Immunology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.; RIKEN Center for Integrative Medical Sciences, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa 230-0045, Japan.
Thaiss CA; Department of Immunology, Weizmann Institute of Science, Rehovot 76100, Israel.
Sato M; RIKEN Center for Sustainable Resource Science, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa 230-0045, Japan.
Toyooka K; RIKEN Center for Sustainable Resource Science, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa 230-0045, Japan.
Said HS; Cooperative Major in Advanced Health Science, Graduate School of Advanced Science and Engineering, Waseda University, Tokyo, Japan.; Department of Microbiology and Immunology, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt.
Yamagami H; Department of Gastroenterology, Osaka City University Graduate School of Medicine, Osaka, Japan.
Rice SA; The Singapore Centre for Environmental Life Sciences Engineering, The School of Biological Sciences, Nanyang Technological University, Singapore.
Gevers D; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Johnson RC; Microbial Genomics Section, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Segre JA; Microbial Genomics Section, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Chen K; Richard King Mellon Foundation Institute for Pediatric Research, Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, PA 15224, USA.
Kolls JK; Richard King Mellon Foundation Institute for Pediatric Research, Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, PA 15224, USA.
Elinav E; Department of Immunology, Weizmann Institute of Science, Rehovot 76100, Israel.
Morita H; Graduate School of Environmental and Life Science, Okayama University, Okayama, Japan.
Xavier RJ; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; Center for Computational and Integrative Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.
Hattori M; Graduate School of Frontier Sciences, The University of Tokyo, 5-1-5 Kashiwanoha, Kashiwa, Chiba 277-8561, Japan. .; Cooperative Major in Advanced Health Science, Graduate School of Advanced Science and Engineering, Waseda University, Tokyo, Japan.
Honda K; Department of Microbiology and Immunology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan. .; RIKEN Center for Integrative Medical Sciences, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa 230-0045, Japan.; Pokaż więcej
Źródło:: Science (New York, N.Y.) [Science] 2017 Oct 20; Vol. 358 (6361), pp. 359-365.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Inflammatory Bowel Diseases/*immunology
Inflammatory Bowel Diseases/*microbiology
Intestines/*immunology
Klebsiella/*immunology
Microbiota/*immunology
Mouth/*microbiology
Th1 Cells/*immunology
Animals ; Anti-Bacterial Agents/pharmacology ; Drug Resistance, Bacterial ; Dysbiosis/immunology ; Dysbiosis/microbiology ; Germ-Free Life ; Intestines/microbiology ; Klebsiella/drug effects ; Klebsiella/isolation & purification ; Klebsiella/pathogenicity ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Saliva/microbiology

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Skocz do pozycji: 10.

Tytuł:: Potential role of intratumor bacteria in mediating tumor resistance to the chemotherapeutic drug gemcitabine.
Autorzy:: Geller LT; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
Barzily-Rokni M; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Danino T; Institute for Medical Engineering and Science, Massachusetts Institute of Technology (MIT), Cambridge, MA 02139, USA.
Jonas OH; Department of Radiology, Brigham and Women's Hospital, Boston, MA 02115, USA.; Joint Center for Cancer Precision Medicine, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
Shental N; Department of Mathematics and Computer Science, Open University of Israel, Raanana, Israel.
Nejman D; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
Gavert N; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
Zwang Y; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
Cooper ZA; Department of Genomic Medicine, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.; Department of Surgical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Shee K; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Thaiss CA; Department of Immunology, Weizmann Institute of Science, Rehovot, Israel.
Reuben A; Department of Surgical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Livny J; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Avraham R; Department of Biological Regulation, Weizmann Institute of Science, Rehovot, Israel.
Frederick DT; Department of Surgical Oncology, Massachusetts General Hospital, Boston, MA 02114, USA.
Ligorio M; Massachusetts General Hospital Cancer Center, Boston, MA 02114, USA.
Chatman K; Small Molecule Mass Spectrometry Facility, Faculty of Arts and Sciences Division of Science, Harvard University, Cambridge, MA 02138, USA.
Johnston SE; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Mosher CM; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Brandis A; Life Sciences Core Facilities, Weizmann Institute of Science, Rehovot, Israel.
Fuks G; Department of Physics of Complex Systems, Weizmann Institute of Science, Rehovot, Israel.
Gurbatri C; Department of Biomedical Engineering, Columbia University, New York City, NY 10027, USA.
Gopalakrishnan V; Department of Surgical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Kim M; Department of Surgical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Hurd MW; Ahmed Center for Pancreatic Cancer Research, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Katz M; Department of Surgical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Fleming J; Department of Surgical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Maitra A; Department of Pathology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Smith DA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Skalak M; Institute for Medical Engineering and Science, Massachusetts Institute of Technology (MIT), Cambridge, MA 02139, USA.
Bu J; Institute for Medical Engineering and Science, Massachusetts Institute of Technology (MIT), Cambridge, MA 02139, USA.
Michaud M; Harvard T. H. Chan School of Public Health, Departments of Immunology and Infectious Diseases and Genetics and Complex Diseases, Boston, MA 02115, USA.
Trauger SA; Small Molecule Mass Spectrometry Facility, Faculty of Arts and Sciences Division of Science, Harvard University, Cambridge, MA 02138, USA.
Barshack I; Department of Pathology, Sheba Medical Center, Ramat Gan, Israel.; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Golan T; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.; Department of Oncology, Sheba Medical Center, Ramat Gan, Israel.
Sandbank J; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Flaherty KT; Massachusetts General Hospital Cancer Center, Boston, MA 02114, USA.
Mandinova A; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; Cutaneous Biology Research Center, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129, USA.
Garrett WS; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; Harvard T. H. Chan School of Public Health, Departments of Immunology and Infectious Diseases and Genetics and Complex Diseases, Boston, MA 02115, USA.; Dana-Farber Cancer Institute, Boston, MA 02115, USA.
Thayer SP; Department of Surgery, University of Nebraska Medical Center, Omaha, NE 68198-6345, USA.
Ferrone CR; Pancreas and Biliary Surgery Program, Massachusetts General Hospital, Boston, MA 02114, USA.
Huttenhower C; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; Department of Biostatistics, Harvard School of Public Health, Boston, MA 02115, USA.
Bhatia SN; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; Harvard-MIT Division of Health Sciences and Technology, MIT, Cambridge, MA 02139, USA.; Howard Hughes Medical Institute (HHMI), Institute for Medical Engineering and Science, MIT, Cambridge, MA 02139, USA.; Division of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.; Department of Electrical Engineering and Computer Science, MIT, Cambridge, MA 02139, USA.; Ludwig Center for Molecular Oncology, MIT, Cambridge, MA 02139, USA.; Marble Center for Cancer Nanomedicine, MIT, Cambridge, MA 02139, USA.
Gevers D; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Wargo JA; Department of Genomic Medicine, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.; Department of Surgical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Golub TR; HHMI, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA.; Harvard Medical School, Boston, MA 02115, USA.
Straussman R; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel. .; Pokaż więcej
Źródło:: Science (New York, N.Y.) [Science] 2017 Sep 15; Vol. 357 (6356), pp. 1156-1160.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Drug Resistance, Neoplasm*
Antimetabolites, Antineoplastic/*therapeutic use
Carcinoma, Pancreatic Ductal/*drug therapy
Carcinoma, Pancreatic Ductal/*microbiology
Deoxycytidine/*analogs & derivatives
Pancreatic Neoplasms/*drug therapy
Pancreatic Neoplasms/*microbiology
Animals ; Colonic Neoplasms/microbiology ; Deoxycytidine/therapeutic use ; Gammaproteobacteria/isolation & purification ; Humans ; Male ; Mice ; Mice, Inbred BALB C ; Mycoplasma hyorhinis/isolation & purification ; Neoplasms, Experimental/drug therapy ; Neoplasms, Experimental/microbiology ; Gemcitabine ; Pancreatic Neoplasms

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Skocz do pozycji: 11.

Tytuł:: Microglia development follows a stepwise program to regulate brain homeostasis.
Autorzy:: Matcovitch-Natan O; Department of Immunology, Weizmann Institute of Science, Rehovot, Israel. Department of Neurobiology, Weizmann Institute of Science, Rehovot, Israel.
Winter DR; Department of Immunology, Weizmann Institute of Science, Rehovot, Israel.
Giladi A; Department of Immunology, Weizmann Institute of Science, Rehovot, Israel.
Vargas Aguilar S; Centre d'Immunologie de Marseille-Luminy (CIML), Université Aix-Marseille, UM2, Campus de Luminy, Marseille, France. Institut National de la Santé et de la Recherche Médicale (INSERM), U1104, Marseille, France. Centre National de la Recherche Scientifique (CNRS), UMR7280, Marseille, France. Max-Delbrück-Centrum für Molekulare Medizin in der Helmholtz-Gemeinschaft (MDC), Robert-Rössle-Straß 10, 13125 Berlin, Germany.
Spinrad A; Department of Immunology, Weizmann Institute of Science, Rehovot, Israel. Department of Neurobiology, Weizmann Institute of Science, Rehovot, Israel.
Sarrazin S; Centre d'Immunologie de Marseille-Luminy (CIML), Université Aix-Marseille, UM2, Campus de Luminy, Marseille, France. Institut National de la Santé et de la Recherche Médicale (INSERM), U1104, Marseille, France. Centre National de la Recherche Scientifique (CNRS), UMR7280, Marseille, France.
Ben-Yehuda H; Department of Neurobiology, Weizmann Institute of Science, Rehovot, Israel.
David E; Department of Immunology, Weizmann Institute of Science, Rehovot, Israel.
Zelada González F; Centre d'Immunologie de Marseille-Luminy (CIML), Université Aix-Marseille, UM2, Campus de Luminy, Marseille, France. Institut National de la Santé et de la Recherche Médicale (INSERM), U1104, Marseille, France. Centre National de la Recherche Scientifique (CNRS), UMR7280, Marseille, France.
Perrin P; Centre d'Immunologie de Marseille-Luminy (CIML), Université Aix-Marseille, UM2, Campus de Luminy, Marseille, France. Institut National de la Santé et de la Recherche Médicale (INSERM), U1104, Marseille, France. Centre National de la Recherche Scientifique (CNRS), UMR7280, Marseille, France.
Keren-Shaul H; Department of Immunology, Weizmann Institute of Science, Rehovot, Israel.
Gury M; Department of Immunology, Weizmann Institute of Science, Rehovot, Israel.
Lara-Astaiso D; Department of Immunology, Weizmann Institute of Science, Rehovot, Israel.
Thaiss CA; Department of Immunology, Weizmann Institute of Science, Rehovot, Israel.
Cohen M; Department of Neurobiology, Weizmann Institute of Science, Rehovot, Israel.
Bahar Halpern K; Department of Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
Baruch K; Department of Neurobiology, Weizmann Institute of Science, Rehovot, Israel.
Deczkowska A; Department of Neurobiology, Weizmann Institute of Science, Rehovot, Israel.
Lorenzo-Vivas E; Department of Immunology, Weizmann Institute of Science, Rehovot, Israel.
Itzkovitz S; Department of Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
Elinav E; Department of Immunology, Weizmann Institute of Science, Rehovot, Israel.
Sieweke MH; Centre d'Immunologie de Marseille-Luminy (CIML), Université Aix-Marseille, UM2, Campus de Luminy, Marseille, France. Institut National de la Santé et de la Recherche Médicale (INSERM), U1104, Marseille, France. Centre National de la Recherche Scientifique (CNRS), UMR7280, Marseille, France. Max-Delbrück-Centrum für Molekulare Medizin in der Helmholtz-Gemeinschaft (MDC), Robert-Rössle-Straß 10, 13125 Berlin, Germany. .
Schwartz M; Department of Neurobiology, Weizmann Institute of Science, Rehovot, Israel. .
Amit I; Department of Immunology, Weizmann Institute of Science, Rehovot, Israel. .; Pokaż więcej
Źródło:: Science (New York, N.Y.) [Science] 2016 Aug 19; Vol. 353 (6301), pp. aad8670. Date of Electronic Publication: 2016 Jun 23.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Brain/*embryology
Homeostasis/*physiology
Microglia/*cytology
Neurogenesis/*immunology
Animals ; Blood-Brain Barrier/embryology ; Blood-Brain Barrier/immunology ; Brain/immunology ; Chromatin/metabolism ; Epigenesis, Genetic ; Female ; Gene Expression Profiling ; Gene Knockout Techniques ; Histone Code ; Homeostasis/genetics ; Immunity/genetics ; MafB Transcription Factor/genetics ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Microglia/immunology ; Myeloid Cells/cytology ; Neurogenesis/genetics ; Single-Cell Analysis

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Skocz do pozycji: 12.

Tytuł:: Metagenomic cross-talk: the regulatory interplay between immunogenomics and the microbiome.
Autorzy:: Levy M; Immunology Department, Weizmann Institute of Science, 100 Herzl Street, Rehovot, 76100, Israel.
Thaiss CA; Immunology Department, Weizmann Institute of Science, 100 Herzl Street, Rehovot, 76100, Israel.
Elinav E; Immunology Department, Weizmann Institute of Science, 100 Herzl Street, Rehovot, 76100, Israel. .; Pokaż więcej
Źródło:: Genome medicine [Genome Med] 2015 Nov 20; Vol. 7, pp. 120. Date of Electronic Publication: 2015 Nov 20.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Metagenomics/*methods
Microbiota/*genetics
Microbiota/*immunology
Animals ; Gastrointestinal Tract/immunology ; Gastrointestinal Tract/microbiology ; Gene Expression Regulation/immunology ; Genome, Microbial/genetics ; Genome, Microbial/immunology ; Humans ; Immune System/microbiology ; Immune System Diseases/immunology ; Immune System Diseases/microbiology

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Skocz do pozycji: 13.

Tytuł:: Q&A: Chance encounters.
Autorzy:: Beutler B
Thaiss CA; Pokaż więcej
Źródło:: Nature [Nature] 2015 Oct 22; Vol. 526 (7574), pp. S59-60.
Typ publikacji:: Historical Article; Interview
MeSH Terms:: Immunity, Innate/*immunology
Allergy and Immunology/history ; Allergy and Immunology/trends ; Animals ; Computer Simulation ; Drug Discovery/methods ; Drug Discovery/trends ; Exome/genetics ; History, 20th Century ; History, 21st Century ; Humans ; Mice ; Mutagenesis ; Neurosciences ; Nobel Prize ; Phenotype

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Skocz do pozycji: 14.

Tytuł:: Chronobiomics: The Biological Clock as a New Principle in Host-Microbial Interactions.
Autorzy:: Thaiss CA; Immunology Department, Weizmann Institute of Science, Rehovot, Israel.
Levy M; Immunology Department, Weizmann Institute of Science, Rehovot, Israel.
Elinav E; Immunology Department, Weizmann Institute of Science, Rehovot, Israel.; Pokaż więcej
Źródło:: PLoS pathogens [PLoS Pathog] 2015 Oct 08; Vol. 11 (10), pp. e1005113. Date of Electronic Publication: 2015 Oct 08 (Print Publication: 2015).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:: Biological Clocks/*physiology
Host-Parasite Interactions/*physiology
Animals ; Humans

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Skocz do pozycji: 15.

Tytuł:: Growth dynamics of gut microbiota in health and disease inferred from single metagenomic samples.
Autorzy:: Korem T; Department of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot, Israel.
Zeevi D; Department of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot, Israel.
Suez J; Immunology Department, Weizmann Institute of Science, Rehovot, Israel.
Weinberger A; Department of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot, Israel.
Avnit-Sagi T; Department of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot, Israel.
Pompan-Lotan M; Department of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot, Israel.
Matot E; Department of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot, Israel.
Jona G; Department of Biological services, Weizmann Institute of Science, Rehovot, Israel.
Harmelin A; Department of Veterinary Resources, Weizmann Institute of Science, Rehovot, Israel.
Cohen N; Department of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot, Israel.
Sirota-Madi A; Center for Computational and Integrative Biology, Massachusetts General Hospital, Harvard Medical School and Broad Institute.
Thaiss CA; Immunology Department, Weizmann Institute of Science, Rehovot, Israel.
Pevsner-Fischer M; Immunology Department, Weizmann Institute of Science, Rehovot, Israel.
Sorek R; Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.
Xavier R; Center for Computational and Integrative Biology, Massachusetts General Hospital, Harvard Medical School and Broad Institute.
Elinav E; Immunology Department, Weizmann Institute of Science, Rehovot, Israel.
Segal E; Department of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot, Israel.; Pokaż więcej
Źródło:: Science (New York, N.Y.) [Science] 2015 Sep 04; Vol. 349 (6252), pp. 1101-1106. Date of Electronic Publication: 2015 Jul 30.
Typ publikacji:: Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Bacteria/*growth & development
Diabetes Mellitus, Type 2/*microbiology
Gastrointestinal Tract/*microbiology
Inflammatory Bowel Diseases/*microbiology
Microbiota/*physiology
Bacteria/classification ; Bacteria/genetics ; Genome, Bacterial ; Humans ; Metagenome ; Metagenomics ; Microbiota/genetics

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Skocz do pozycji: 16.

Tytuł:: Taming the inflammasome.
Autorzy:: Levy M; Immunology Department, Weizmann Institute of Science, Rehovot, Israel.
Thaiss CA; Immunology Department, Weizmann Institute of Science, Rehovot, Israel.
Elinav E; Immunology Department, Weizmann Institute of Science, Rehovot, Israel.; Pokaż więcej
Źródło:: Nature medicine [Nat Med] 2015 Mar; Vol. 21 (3), pp. 213-5.
Typ publikacji:: Journal Article
MeSH Terms:: 3-Hydroxybutyric Acid/*therapeutic use
Carrier Proteins/*antagonists & inhibitors
Inflammasomes/*antagonists & inhibitors
Inflammation/*drug therapy
Atherosclerosis/drug therapy ; Diabetes Mellitus, Type 2/drug therapy ; Gout/drug therapy ; Humans ; NLR Family, Pyrin Domain-Containing 3 Protein

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Skocz do pozycji: 17.

Tytuł:: Inflammasomes and the microbiota--partners in the preservation of mucosal homeostasis.
Autorzy:: Levy M; Immunology Department, Weizmann Institute of Science, 100 Herzl Street, 76100, Rehovot, Israel.
Thaiss CA
Katz MN
Suez J
Elinav E; Pokaż więcej
Źródło:: Seminars in immunopathology [Semin Immunopathol] 2015 Jan; Vol. 37 (1), pp. 39-46. Date of Electronic Publication: 2014 Oct 15.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:: Homeostasis/*immunology
Immunity, Innate/*immunology
Inflammasomes/*immunology
Microbiota/*immunology
Symbiosis/*immunology
Humans

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Skocz do pozycji: 18.

Tytuł:: Artificial sweeteners induce glucose intolerance by altering the gut microbiota.
Autorzy:: Suez J; Department of Immunology, Weizmann Institute of Science, Rehovot 76100, Israel.
Korem T; 1] Department of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot 76100, Israel [2].
Zeevi D; 1] Department of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot 76100, Israel [2].
Zilberman-Schapira G; 1] Department of Immunology, Weizmann Institute of Science, Rehovot 76100, Israel [2].
Thaiss CA; Department of Immunology, Weizmann Institute of Science, Rehovot 76100, Israel.
Maza O; Department of Immunology, Weizmann Institute of Science, Rehovot 76100, Israel.
Israeli D; Day Care Unit and the Laboratory of Imaging and Brain Stimulation, Kfar Shaul hospital, Jerusalem Center for Mental Health, Jerusalem 91060, Israel.
Zmora N; 1] Internal Medicine Department, Tel Aviv Sourasky Medical Center, Tel Aviv 64239, Israel [2] Research Center for Digestive Tract and Liver Diseases, Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 69978, Israel [3] Digestive Center, Tel Aviv Sourasky Medical Center, Tel Aviv 64239, Israel.
Gilad S; The Nancy and Stephen Grand Israel National Center for Personalized Medicine (INCPM), Weizmann Institute of Science, Rehovot 76100, Israel.
Weinberger A; Department of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot 76100, Israel.
Kuperman Y; Department of Veterinary Resources, Weizmann Institute of Science, Rehovot 76100, Israel.
Harmelin A; Department of Veterinary Resources, Weizmann Institute of Science, Rehovot 76100, Israel.
Kolodkin-Gal I; Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 76100, Israel.
Shapiro H; Department of Immunology, Weizmann Institute of Science, Rehovot 76100, Israel.
Halpern Z; 1] Research Center for Digestive Tract and Liver Diseases, Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 69978, Israel [2] Digestive Center, Tel Aviv Sourasky Medical Center, Tel Aviv 64239, Israel.
Segal E; Department of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot 76100, Israel.
Elinav E; Department of Immunology, Weizmann Institute of Science, Rehovot 76100, Israel.; Pokaż więcej
Źródło:: Nature [Nature] 2014 Oct 09; Vol. 514 (7521), pp. 181-6. Date of Electronic Publication: 2014 Sep 17.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Gastrointestinal Tract/*drug effects
Gastrointestinal Tract/*microbiology
Glucose Intolerance/*chemically induced
Glucose Intolerance/*microbiology
Microbiota/*drug effects
Sweetening Agents/*adverse effects
Animals ; Anti-Bacterial Agents/pharmacology ; Aspartame/adverse effects ; Body Weight/drug effects ; Diet, High-Fat ; Dietary Fats/pharmacology ; Feces/microbiology ; Female ; Germ-Free Life ; Glucose/metabolism ; Glucose Intolerance/metabolism ; Humans ; Male ; Metabolic Syndrome/chemically induced ; Metabolic Syndrome/metabolism ; Metabolic Syndrome/microbiology ; Mice ; Mice, Inbred C57BL ; Saccharin/administration & dosage ; Saccharin/adverse effects ; Sucrose/adverse effects ; Sucrose/analogs & derivatives ; Waist-Hip Ratio