Autor: "Thein TL" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: A nonstructural protein 1 capture enzyme-linked immunosorbent assay specific for dengue viruses.
Autorzy:: Lim PY; Singapore Immunology Network, Agency for Science, Technology and Research, Singapore, Singapore.
Ramapraba A; Singapore Immunology Network, Agency for Science, Technology and Research, Singapore, Singapore.
Loy T; Singapore Immunology Network, Agency for Science, Technology and Research, Singapore, Singapore.
Rouers A; Singapore Immunology Network, Agency for Science, Technology and Research, Singapore, Singapore.
Thein TL; National Centre for Infectious Diseases, Singapore, Singapore.
Leo YS; National Centre for Infectious Diseases, Singapore, Singapore.
Burton DR; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, United States of America.
Fink K; Singapore Immunology Network, Agency for Science, Technology and Research, Singapore, Singapore.
Wang CI; Singapore Immunology Network, Agency for Science, Technology and Research, Singapore, Singapore.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2023 May 18; Vol. 18 (5), pp. e0285878. Date of Electronic Publication: 2023 May 18 (Print Publication: 2023).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Dengue Virus*
Dengue*
Zika Virus Infection*
Zika Virus*
Humans ; Sensitivity and Specificity ; Antibodies, Viral ; Viral Nonstructural Proteins ; Cross Reactions ; Enzyme-Linked Immunosorbent Assay ; Epitopes

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Skocz do pozycji: 2.

Tytuł:: Differentiating coronavirus disease 2019 (COVID-19) from influenza and dengue.
Autorzy:: Thein TL; National Centre for Infectious Diseases, 16 Jalan Tan Tock Seng, Singapore, 308442, Singapore.
Ang LW; National Centre for Infectious Diseases, 16 Jalan Tan Tock Seng, Singapore, 308442, Singapore.
Young BE; National Centre for Infectious Diseases, 16 Jalan Tan Tock Seng, Singapore, 308442, Singapore.; Department of Infectious Diseases, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore, 308433, Singapore.; Lee Kong Chian School of Medicine, Nanyang Technological University, 11 Mandalay Road, Singapore, 308232, Singapore.
Chen MI; National Centre for Infectious Diseases, 16 Jalan Tan Tock Seng, Singapore, 308442, Singapore.; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, 12 Science Drive 2, #10-01, Singapore, 117549, Singapore.
Leo YS; National Centre for Infectious Diseases, 16 Jalan Tan Tock Seng, Singapore, 308442, Singapore. Yee_Sin_.; Department of Infectious Diseases, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore, 308433, Singapore. Yee_Sin_.; Lee Kong Chian School of Medicine, Nanyang Technological University, 11 Mandalay Road, Singapore, 308232, Singapore. Yee_Sin_.; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, 12 Science Drive 2, #10-01, Singapore, 117549, Singapore. Yee_Sin_.; Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, 10 Medical Drive, Singapore, 117597, Singapore. Yee_Sin_.
Lye DCB; National Centre for Infectious Diseases, 16 Jalan Tan Tock Seng, Singapore, 308442, Singapore. David_.; Department of Infectious Diseases, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore, 308433, Singapore. David_.; Lee Kong Chian School of Medicine, Nanyang Technological University, 11 Mandalay Road, Singapore, 308232, Singapore. David_.; Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, 10 Medical Drive, Singapore, 117597, Singapore. David_.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2021 Oct 05; Vol. 11 (1), pp. 19713. Date of Electronic Publication: 2021 Oct 05.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: COVID-19/*pathology
Dengue/*pathology
Influenza, Human/*pathology
Adult ; Area Under Curve ; COVID-19/complications ; COVID-19/virology ; Cohort Studies ; Dengue/complications ; Dengue/virology ; Diagnosis, Differential ; Diarrhea/etiology ; Female ; Fever/etiology ; Humans ; Influenza, Human/complications ; Influenza, Human/virology ; Lymphocyte Count ; Male ; Middle Aged ; Platelet Count ; RNA, Viral/analysis ; RNA, Viral/metabolism ; ROC Curve ; SARS-CoV-2/genetics ; SARS-CoV-2/isolation & purification ; Vomiting/etiology ; Young Adult

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Skocz do pozycji: 3.

Tytuł:: Competitive ELISA for a serologic test to detect dengue serotype-specific anti-NS1 IgGs using high-affinity UB-DNA aptamers.
Autorzy:: Matsunaga KI; Institute of Bioengineering and Bioimaging, 31 Biopolis Way, The Nanos, #07-01, Singapore, 138669, Singapore.
Kimoto M; Institute of Bioengineering and Bioimaging, 31 Biopolis Way, The Nanos, #07-01, Singapore, 138669, Singapore.
Lim VW; National Centre for Infectious Diseases, 16 Jalan Tan Tock Seng, Singapore, 308442, Singapore.
Thein TL; National Centre for Infectious Diseases, 16 Jalan Tan Tock Seng, Singapore, 308442, Singapore.
Vasoo S; National Centre for Infectious Diseases, 16 Jalan Tan Tock Seng, Singapore, 308442, Singapore.; Department of Infectious Diseases, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore, 308433, Singapore.; Lee Kong Chian School of Medicine, Nanyang Technological University, 59 Nanyang Dr., Experimental Medicine Building, Singapore, 636921, Singapore.
Leo YS; National Centre for Infectious Diseases, 16 Jalan Tan Tock Seng, Singapore, 308442, Singapore.; Department of Infectious Diseases, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore, 308433, Singapore.; Lee Kong Chian School of Medicine, Nanyang Technological University, 59 Nanyang Dr., Experimental Medicine Building, Singapore, 636921, Singapore.; Saw Swee Hock School of Public Health, National University of Singapore, 12 Science Drive 2, #10-01, Singapore, 117549, Singapore.
Sun W; Institute of Bioengineering and Bioimaging, 31 Biopolis Way, The Nanos, #07-01, Singapore, 138669, Singapore.; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117593, Singapore.
Hirao I; Institute of Bioengineering and Bioimaging, 31 Biopolis Way, The Nanos, #07-01, Singapore, 138669, Singapore. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2021 Sep 09; Vol. 11 (1), pp. 18000. Date of Electronic Publication: 2021 Sep 09.
Typ publikacji:: Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Antibody Affinity*
Serogroup*
Antibodies, Viral/*immunology
Aptamers, Nucleotide/*immunology
Dengue/*immunology
Dengue Virus/*immunology
Immunoglobulin G/*immunology
Serologic Tests/*methods
Viral Nonstructural Proteins/*immunology
Antibodies, Viral/blood ; Antigens, Viral/immunology ; Cross Reactions ; Dengue/blood ; Dengue/diagnosis ; Dengue/virology ; Enzyme-Linked Immunosorbent Assay/methods ; Humans ; Immunoglobulin G/blood ; Sensitivity and Specificity ; Zika Virus/immunology ; Zika Virus Infection/blood ; Zika Virus Infection/diagnosis ; Zika Virus Infection/immunology ; Zika Virus Infection/virology

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Skocz do pozycji: 4.

Tytuł:: Author Correction: Increased Serum Hyaluronic Acid and Heparan Sulfate in Dengue Fever: Association with Plasma Leakage and Disease Severity.
Autorzy:: Tang TH; Division of Infectious Diseases, Department of Medicine, Queen Elizabeth Hospital, Yau Ma Tei, Hong Kong SAR, Hong Kong. .
Alonso S; Department of Microbiology, Yong Loo Lin School of Medicine and Immunology Programme, Life Sciences Institute, National University of Singapore, Singapore, Singapore.
Ng LF; Laboratory of Microbial Immunity, Singapore Immunology Network (SIgN), A*STAR, Singapore, Singapore.
Thein TL; Communicable Disease Centre, Institute of Infectious Diseases and Epidemiology, Tan Tock Seng Hospital, Singapore, Singapore.
Pang J; Communicable Disease Centre, Institute of Infectious Diseases and Epidemiology, Tan Tock Seng Hospital, Singapore, Singapore.; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.
Leo YS; Communicable Disease Centre, Institute of Infectious Diseases and Epidemiology, Tan Tock Seng Hospital, Singapore, Singapore.; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Lye DC; Communicable Disease Centre, Institute of Infectious Diseases and Epidemiology, Tan Tock Seng Hospital, Singapore, Singapore.; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Yeo TW; Communicable Disease Centre, Institute of Infectious Diseases and Epidemiology, Tan Tock Seng Hospital, Singapore, Singapore. .; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2021 Jun 21; Vol. 11 (1), pp. 13346. Date of Electronic Publication: 2021 Jun 21.
Typ publikacji:: Published Erratum

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Skocz do pozycji: 5.

Tytuł:: Government trust, perceptions of COVID-19 and behaviour change: cohort surveys, Singapore.
Autorzy:: Lim VW; Infectious Disease Research and Training Office, National Centre for Infectious Diseases, 16 Jln Tan Tock Seng, Singapore 308442, Singapore.
Lim RL; Infectious Disease Research and Training Office, National Centre for Infectious Diseases, 16 Jln Tan Tock Seng, Singapore 308442, Singapore.
Tan YR; Infectious Disease Research and Training Office, National Centre for Infectious Diseases, 16 Jln Tan Tock Seng, Singapore 308442, Singapore.
Soh AS; Infectious Disease Research and Training Office, National Centre for Infectious Diseases, 16 Jln Tan Tock Seng, Singapore 308442, Singapore.
Tan MX; Infectious Disease Research and Training Office, National Centre for Infectious Diseases, 16 Jln Tan Tock Seng, Singapore 308442, Singapore.
Othman NB; Infectious Disease Research and Training Office, National Centre for Infectious Diseases, 16 Jln Tan Tock Seng, Singapore 308442, Singapore.
Borame Dickens S; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.
Thein TL; Infectious Disease Research and Training Office, National Centre for Infectious Diseases, 16 Jln Tan Tock Seng, Singapore 308442, Singapore.
Lwin MO; Wee Kim Wee School of Communication and Information, Nanyang Technological University, Singapore, Singapore.
Ong RT; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.
Leo YS; Infectious Disease Research and Training Office, National Centre for Infectious Diseases, 16 Jln Tan Tock Seng, Singapore 308442, Singapore.
Lee VJ; Communicable Diseases Division, Ministry of Health, Singapore, Singapore.
Chen MI; Infectious Disease Research and Training Office, National Centre for Infectious Diseases, 16 Jln Tan Tock Seng, Singapore 308442, Singapore.; Pokaż więcej
Źródło:: Bulletin of the World Health Organization [Bull World Health Organ] 2021 Feb 01; Vol. 99 (2), pp. 92-101. Date of Electronic Publication: 2020 Oct 28.
Typ publikacji:: Journal Article
MeSH Terms:: COVID-19*
Government*
Health Knowledge, Attitudes, Practice*
Public Opinion*
Trust*
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Female ; Humans ; Male ; Middle Aged ; Pandemics ; Risk Assessment ; Singapore ; Surveys and Questionnaires ; Young Adult

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Skocz do pozycji: 6.

Tytuł:: Single molecule, near full-length genome sequencing of dengue virus.
Autorzy:: Adikari TN; School of Medical Sciences, University of New South Wales, Sydney, Australia.; Institute for Combinatorial Advanced Research and Education, Sir John Kotelawala Defence University, Ratmalana, Sri Lanka.
Riaz N; Kirby Institute, University of New South Wales, Sydney, Australia.; Department of Microbiology, Hazara University, Mansehra, KPK, Pakistan.
Sigera C; Department of Parasitology, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka.
Leung P; Kirby Institute, University of New South Wales, Sydney, Australia.
Valencia BM; Kirby Institute, University of New South Wales, Sydney, Australia.
Barton K; Garvan Institute of Medical Research, Sydney, Australia and St-Vincent's Clinical School, Faculty of Medicine, UNSW, Sydney, Australia.
Smith MA; Garvan Institute of Medical Research, Sydney, Australia and St-Vincent's Clinical School, Faculty of Medicine, UNSW, Sydney, Australia.; CHU Sainte-Justine Research Centre, Montreal, Canada.; Department of Biochemistry and Molecular Medicine, Université de Montréal, Montreal, Canada.
Bull RA; School of Medical Sciences, University of New South Wales, Sydney, Australia.; Kirby Institute, University of New South Wales, Sydney, Australia.
Li H; Kirby Institute, University of New South Wales, Sydney, Australia.
Luciani F; School of Medical Sciences, University of New South Wales, Sydney, Australia.; Kirby Institute, University of New South Wales, Sydney, Australia.
Weeratunga P; Department of Clinical Medicine, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka.
Thein TL; National Centre for Infectious Diseases, Singapore, Singapore.
Lim VWX; National Centre for Infectious Diseases, Singapore, Singapore.
Leo YS; National Centre for Infectious Diseases, Singapore, Singapore.; Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore, Singapore.; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Lee Kong Chian School of Medicine, Singapore, Singapore.
Rajapakse S; Department of Clinical Medicine, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka.
Fink K; Agency for Science, Technology and Research, Singapore, Singapore.
Lloyd AR; Kirby Institute, University of New South Wales, Sydney, Australia.
Fernando D; Department of Parasitology, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka.
Rodrigo C; School of Medical Sciences, University of New South Wales, Sydney, Australia. .; Kirby Institute, University of New South Wales, Sydney, Australia. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2020 Oct 23; Vol. 10 (1), pp. 18196. Date of Electronic Publication: 2020 Oct 23.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Genome, Viral*
Dengue Virus/*genetics
High-Throughput Nucleotide Sequencing/*methods
Humans ; Likelihood Functions ; Phylogeny

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Skocz do pozycji: 7.

Tytuł:: Blood pressure trend in hospitalized adult dengue patients.
Autorzy:: Yeung W; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Lye DCB; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore, Singapore.; National Centre for Infectious Diseases, Singapore, Singapore.
Thein TL; National Centre for Infectious Diseases, Singapore, Singapore.
Chen Y; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.
Leo YS; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore, Singapore.; National Centre for Infectious Diseases, Singapore, Singapore.; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2020 Jul 01; Vol. 15 (7), pp. e0235166. Date of Electronic Publication: 2020 Jul 01 (Print Publication: 2020).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Blood Pressure*
Dengue/*physiopathology
Adult ; Dengue/complications ; Dengue Virus/isolation & purification ; Female ; Hospitalization ; Humans ; Hypertension/complications ; Hypertension/physiopathology ; Male ; Middle Aged ; Young Adult

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Skocz do pozycji: 8.

Tytuł:: A 15-year review of dengue hospitalizations in Singapore: Reducing admissions without adverse consequences, 2003 to 2017.
Autorzy:: Ang LW; National Centre for Infectious Diseases, Singapore.; Public Health Group, Ministry of Health, Singapore.
Thein TL; National Centre for Infectious Diseases, Singapore.
Ng Y; Public Health Group, Ministry of Health, Singapore.
Boudville IC; National Centre for Infectious Diseases, Singapore.
Chia PY; National Centre for Infectious Diseases, Singapore.; Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore.
Lee VJM; Public Health Group, Ministry of Health, Singapore.; Saw Swee Hock School of Public Health, National University of Singapore, Singapore.
Leo YS; National Centre for Infectious Diseases, Singapore.; Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore.; Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; Pokaż więcej
Źródło:: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2019 May 15; Vol. 13 (5), pp. e0007389. Date of Electronic Publication: 2019 May 15 (Print Publication: 2019).
Typ publikacji:: Journal Article
MeSH Terms:: Dengue/*epidemiology
Dengue/*therapy
Hospitalization/*statistics & numerical data
Adult ; Aged ; Aged, 80 and over ; Female ; Humans ; Intensive Care Units/statistics & numerical data ; Length of Stay ; Male ; Middle Aged ; Retrospective Studies ; Singapore/epidemiology

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Skocz do pozycji: 9.

Tytuł:: Comparing patient and healthcare worker experiences during a dengue outbreak in Singapore: understanding the patient journey and the introduction of a point-of-care test (POCT) toward better care delivery.
Autorzy:: Tan Q; Saw Swee Hock School of Public Health, National University of Singapore, Tahir Foundation Building, Block MD1, 12 Science Drive 2, Singapore, 117549, Singapore. tan_qing_.; Biological Resource Centre, Agency for Science, Technology and Research (A*Star), Singapore, Singapore. tan_qing_.
Hildon ZJ; Saw Swee Hock School of Public Health, National University of Singapore, Tahir Foundation Building, Block MD1, 12 Science Drive 2, Singapore, 117549, Singapore.; London School of Hygiene and Tropical Medicine, London, United Kingdom.; Johns Hopkins Bloomberg School of Public Health, Centre for Communication Programs, 111 Market Place, Suite 310, Baltimore, Maryland, 21202, USA.
Singh S; Saw Swee Hock School of Public Health, National University of Singapore, Tahir Foundation Building, Block MD1, 12 Science Drive 2, Singapore, 117549, Singapore.
Jing J; Institute of Infectious Diseases & Epidemiology, Communicable Disease Centre; Tan Tock Seng Hospital, Moulmein Road, Singapore, 308433, Singapore.
Thein TL; Institute of Infectious Diseases & Epidemiology, Communicable Disease Centre; Tan Tock Seng Hospital, Moulmein Road, Singapore, 308433, Singapore.
Coker R; London School of Hygiene and Tropical Medicine, London, United Kingdom.; Mahidol University, 9th Floor, Satharanaukwisit Bldg, 420/1 Rajwithi Rd, Bangkok, -10400, Thailand.
Vrijhoef HJM; Saw Swee Hock School of Public Health, National University of Singapore, Tahir Foundation Building, Block MD1, 12 Science Drive 2, Singapore, 117549, Singapore.; National University Health System, Singapore, Singapore.; Department of Patient & Care, Maastricht University Medical Center, Maastricht, Netherlands.; Department of Family Medicine, Vrije Universiteit Brussel, Brussels, Belgium.
Leo YS; Saw Swee Hock School of Public Health, National University of Singapore, Tahir Foundation Building, Block MD1, 12 Science Drive 2, Singapore, 117549, Singapore.; Institute of Infectious Diseases & Epidemiology, Communicable Disease Centre; Tan Tock Seng Hospital, Moulmein Road, Singapore, 308433, Singapore.; Pokaż więcej
Źródło:: BMC infectious diseases [BMC Infect Dis] 2017 Jul 19; Vol. 17 (1), pp. 503. Date of Electronic Publication: 2017 Jul 19.
Typ publikacji:: Journal Article
MeSH Terms:: Delivery of Health Care*
Health Personnel*
Dengue/*diagnosis
Adult ; Attitude of Health Personnel ; Dengue/epidemiology ; Dengue/therapy ; Disease Outbreaks ; Female ; Focus Groups ; Humans ; Male ; Middle Aged ; Point-of-Care Systems ; Public Opinion ; Reagent Kits, Diagnostic ; Singapore/epidemiology ; Time Factors

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Skocz do pozycji: 10.

Tytuł:: Assessing changes in knowledge, attitude and practices on dengue diagnosis and management among primary care physicians after the largest dengue epidemic in Singapore.
Autorzy:: Pang J; Institute of Infectious Diseases and Epidemiology, Tan Tock Seng Hospital, 144 Moulmein Road, Singapore, 308089, Singapore. .; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore. .
Hildon ZJ; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.; Johns Hopkins Center for Communication Programs, Johns Hopkins University, Baltimore, USA.; Department of Global Health and Development, Faculty of Public Health & Policy, London School of Hygiene and Tropical Medicine, London, UK.
Thein TL; Institute of Infectious Diseases and Epidemiology, Tan Tock Seng Hospital, 144 Moulmein Road, Singapore, 308089, Singapore.
Jin J; Institute of Infectious Diseases and Epidemiology, Tan Tock Seng Hospital, 144 Moulmein Road, Singapore, 308089, Singapore.
Leo YS; Institute of Infectious Diseases and Epidemiology, Tan Tock Seng Hospital, 144 Moulmein Road, Singapore, 308089, Singapore.; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.; Pokaż więcej
Źródło:: BMC infectious diseases [BMC Infect Dis] 2017 Jun 15; Vol. 17 (1), pp. 428. Date of Electronic Publication: 2017 Jun 15.
Typ publikacji:: Journal Article
MeSH Terms:: Health Knowledge, Attitudes, Practice*
Physicians, Primary Care*/statistics & numerical data
Dengue/*diagnosis
Adult ; Dengue/epidemiology ; Epidemics ; Female ; Health Surveys ; Humans ; Logistic Models ; Male ; Middle Aged ; Odds Ratio ; Point-of-Care Systems ; Reagent Kits, Diagnostic ; Referral and Consultation ; Singapore/epidemiology

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Skocz do pozycji: 11.

Tytuł:: Increased Serum Hyaluronic Acid and Heparan Sulfate in Dengue Fever: Association with Plasma Leakage and Disease Severity.
Autorzy:: Tang TH; Division of Infectious Diseases, Department of Medicine, Queen Elizabeth Hospital, Hong Kong SAR.
Alonso S; Department of Microbiology, Yong Loo Lin School of Medicine and Immunology programme, Life Sciences Institute, National University of Singapore, Singapore.
Ng LF; Laboratory of Microbial Immunity, Singapore Immunology Network (SIgN), A*STAR, Singapore.
Thein TL; Communicable Disease Centre, Institute of Infectious Diseases and Epidemiology, Tan Tock Seng Hospital, Singapore.
Pang VJ; Communicable Disease Centre, Institute of Infectious Diseases and Epidemiology, Tan Tock Seng Hospital, Singapore.; Saw Swee Hock School of Public Health, National University of Singapore, Singapore.
Leo YS; Communicable Disease Centre, Institute of Infectious Diseases and Epidemiology, Tan Tock Seng Hospital, Singapore.; Saw Swee Hock School of Public Health, National University of Singapore, Singapore.; Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Lye DC; Communicable Disease Centre, Institute of Infectious Diseases and Epidemiology, Tan Tock Seng Hospital, Singapore.; Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Yeo TW; Communicable Disease Centre, Institute of Infectious Diseases and Epidemiology, Tan Tock Seng Hospital, Singapore.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2017 Apr 10; Vol. 7, pp. 46191. Date of Electronic Publication: 2017 Apr 10.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Severity of Illness Index*
Dengue/*blood
Dengue/*pathology
Heparitin Sulfate/*blood
Hyaluronic Acid/*blood
Acute Disease ; Adult ; Biomarkers/blood ; Cytokines/blood ; Female ; Humans ; Inflammation Mediators/metabolism ; Male ; Middle Aged

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Skocz do pozycji: 12.

Tytuł:: The Significance of Prolonged and Saddleback Fever in Hospitalised Adult Dengue.
Autorzy:: Ng DH; Communicable Disease Centre, Institute of Infectious Diseases and Epidemiology, Singapore, Singapore.
Wong JG; Communicable Disease Centre, Institute of Infectious Diseases and Epidemiology, Singapore, Singapore.
Thein TL; Communicable Disease Centre, Institute of Infectious Diseases and Epidemiology, Singapore, Singapore.
Leo YS; Communicable Disease Centre, Institute of Infectious Diseases and Epidemiology, Singapore, Singapore.; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.; Saw Swee Hock School of Public Health, Singapore, Singapore.
Lye DC; Communicable Disease Centre, Institute of Infectious Diseases and Epidemiology, Singapore, Singapore.; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2016 Dec 09; Vol. 11 (12), pp. e0167025. Date of Electronic Publication: 2016 Dec 09 (Print Publication: 2016).
Typ publikacji:: Journal Article
MeSH Terms:: Dengue/*diagnosis
Dengue Virus/*genetics
Fever/*diagnosis
Severe Dengue/*diagnosis
Abdominal Pain/diagnosis ; Adolescent ; Adult ; Cross Infection/diagnosis ; Dengue/virology ; Dengue Virus/physiology ; Diarrhea/diagnosis ; Female ; Hospitalization/statistics & numerical data ; Host-Pathogen Interactions ; Humans ; Male ; Middle Aged ; Polymerase Chain Reaction/methods ; Prognosis ; Severe Dengue/virology ; Severity of Illness Index ; Singapore ; Time Factors ; Young Adult

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Skocz do pozycji: 13.

Tytuł:: Epidemiological risk factors for adult dengue in Singapore: an 8-year nested test negative case control study.
Autorzy:: Yung CF; Infectious Disease Service, Department of Paediatrics, KK Women's and Children's Hospital, Singapore, Singapore. .; Communicable Disease Centre, Institute of Infectious Diseases and Epidemiology, Tan Tock Seng Hospital, Singapore, Singapore. .
Chan SP; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Faculty of Science, Technology and Engineering, La Trobe University, Melbourne, Australia.
Thein TL; Communicable Disease Centre, Institute of Infectious Diseases and Epidemiology, Tan Tock Seng Hospital, Singapore, Singapore.
Chai SC; Communicable Disease Centre, Institute of Infectious Diseases and Epidemiology, Tan Tock Seng Hospital, Singapore, Singapore.
Leo YS; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Communicable Disease Centre, Institute of Infectious Diseases and Epidemiology, Tan Tock Seng Hospital, Singapore, Singapore.; Lee Kong Chian School of Medicine, Nanyang Technological University Singapore, Singapore, Singapore.; Saw Swee Hock School of Public Health, National University Singapore, Singapore, Singapore.; Pokaż więcej
Źródło:: BMC infectious diseases [BMC Infect Dis] 2016 Jul 08; Vol. 16, pp. 323. Date of Electronic Publication: 2016 Jul 08.
Typ publikacji:: Journal Article; Multicenter Study
MeSH Terms:: Dengue/*epidemiology
Adult ; Age Distribution ; Aged ; Case-Control Studies ; Dengue/etiology ; Dengue Virus/isolation & purification ; Female ; Fever ; Humans ; Male ; Middle Aged ; Prospective Studies ; Regression Analysis ; Residence Characteristics ; Risk Factors ; Sex Distribution ; Singapore/epidemiology ; Travel ; Workplace ; Young Adult

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Skocz do pozycji: 14.

Tytuł:: Discovery and Validation of Prognostic Biomarker Models to Guide Triage among Adult Dengue Patients at Early Infection.
Autorzy:: Pang J; Infectious Disease, Genome Institute of Singapore, Singapore, Singapore.; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.; Communicable Diseases Center, Institute of Infectious Diseases and Epidemiology, Tan Tock Seng Hospital, Singapore, Singapore.
Lindblom A; Infectious Disease, Genome Institute of Singapore, Singapore, Singapore.; Department of Medicine Solna, Unit of Infectious Diseases, Center for Molecular Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
Tolfvenstam T; Infectious Disease, Genome Institute of Singapore, Singapore, Singapore.; Department of Medicine Solna, Unit of Infectious Diseases, Center for Molecular Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.; Unit for Highly Pathogenic Viruses, Public Health Agency of Sweden, Stockholm, Sweden.
Thein TL; Communicable Diseases Center, Institute of Infectious Diseases and Epidemiology, Tan Tock Seng Hospital, Singapore, Singapore.
Naim AN; Infectious Disease, Genome Institute of Singapore, Singapore, Singapore.
Ling L; Infectious Disease, Genome Institute of Singapore, Singapore, Singapore.
Chow A; Program in Emerging Infectious Diseases, Duke-NUS Graduate Medical School, Singapore, Singapore.
Chen MI; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.; Communicable Diseases Center, Institute of Infectious Diseases and Epidemiology, Tan Tock Seng Hospital, Singapore, Singapore.
Ooi EE; Program in Emerging Infectious Diseases, Duke-NUS Graduate Medical School, Singapore, Singapore.; DSO National Laboratories, Singapore, Singapore.
Leo YS; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.; Communicable Diseases Center, Institute of Infectious Diseases and Epidemiology, Tan Tock Seng Hospital, Singapore, Singapore.; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Hibberd ML; Infectious Disease, Genome Institute of Singapore, Singapore, Singapore.; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.; London School of Hygiene & Tropical Medicine, London, United Kingdom.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2016 Jun 10; Vol. 11 (6), pp. e0155993. Date of Electronic Publication: 2016 Jun 10 (Print Publication: 2016).
Typ publikacji:: Journal Article; Validation Study
MeSH Terms:: Biomarkers/*analysis
Dengue/*diagnosis
Triage/*methods
Adult ; Aged ; Biomarkers/metabolism ; Case-Control Studies ; Dengue/classification ; Dengue/genetics ; Dengue/therapy ; Early Diagnosis ; Female ; Gene Expression Profiling ; Hospitalization ; Humans ; Male ; Microarray Analysis ; Middle Aged ; Prognosis ; Sensitivity and Specificity ; Young Adult

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Skocz do pozycji: 15.

Tytuł:: Serum Metabolomics Reveals Serotonin as a Predictor of Severe Dengue in the Early Phase of Dengue Fever.
Autorzy:: Cui L; Infectious Diseases Interdisciplinary Research Group, Singapore-MIT Alliance for Research and Technology (SMART), Singapore.
Lee YH; KK Research Centre, KK Women's and Children's Hospital, Singapore.
Thein TL; Communicable Disease Center, Institute of Infectious Diseases and Epidemiology, Tan Tock Seng Hospital, Singapore.
Fang J; Saw Swee Hock School of Public Health, National University of Singapore, Singapore.
Pang J; Communicable Disease Center, Institute of Infectious Diseases and Epidemiology, Tan Tock Seng Hospital, Singapore.; Saw Swee Hock School of Public Health, National University of Singapore, Singapore.
Ooi EE; Infectious Diseases Interdisciplinary Research Group, Singapore-MIT Alliance for Research and Technology (SMART), Singapore.; Emerging Infectious Diseases Program, Duke-NUS Graduate Medical School, Singapore.
Leo YS; Communicable Disease Center, Institute of Infectious Diseases and Epidemiology, Tan Tock Seng Hospital, Singapore.; Saw Swee Hock School of Public Health, National University of Singapore, Singapore.
Ong CN; Saw Swee Hock School of Public Health, National University of Singapore, Singapore.; NUS Environment Research Institute, National University of Singapore, Singapore.
Tannenbaum SR; Infectious Diseases Interdisciplinary Research Group, Singapore-MIT Alliance for Research and Technology (SMART), Singapore.; Departments of Biological Engineering and Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America.; Pokaż więcej
Źródło:: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2016 Apr 07; Vol. 10 (4), pp. e0004607. Date of Electronic Publication: 2016 Apr 07 (Print Publication: 2016).
Typ publikacji:: Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Metabolome*
Biomarkers/*blood
Serotonin/*blood
Serum/*chemistry
Severe Dengue/*diagnosis
Chromatography, Liquid ; Cytokines/blood ; Humans ; Kynurenine/blood ; Mass Spectrometry ; Prognosis ; Severe Dengue/pathology

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Skocz do pozycji: 16.

Tytuł:: Potential Harm of Prophylactic Platelet Transfusion in Adult Dengue Patients.
Autorzy:: Lee TH; Communicable Disease Center, Institute of Infectious Diseases and Epidemiology, Tan Tock Seng Hospital, Singapore.
Wong JG; Communicable Disease Center, Institute of Infectious Diseases and Epidemiology, Tan Tock Seng Hospital, Singapore.
Leo YS; Communicable Disease Center, Institute of Infectious Diseases and Epidemiology, Tan Tock Seng Hospital, Singapore.; Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Thein TL; Communicable Disease Center, Institute of Infectious Diseases and Epidemiology, Tan Tock Seng Hospital, Singapore.
Ng EL; Communicable Disease Center, Institute of Infectious Diseases and Epidemiology, Tan Tock Seng Hospital, Singapore.
Lee LK; Communicable Disease Center, Institute of Infectious Diseases and Epidemiology, Tan Tock Seng Hospital, Singapore.
Lye DC; Communicable Disease Center, Institute of Infectious Diseases and Epidemiology, Tan Tock Seng Hospital, Singapore.; Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; Pokaż więcej
Źródło:: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2016 Mar 25; Vol. 10 (3), pp. e0004576. Date of Electronic Publication: 2016 Mar 25 (Print Publication: 2016).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Dengue/*complications
Platelet Transfusion/*adverse effects
Thrombocytopenia/*etiology
Thrombocytopenia/*prevention & control
Adult ; Aged ; Female ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Young Adult

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Skocz do pozycji: 17.

Tytuł:: Identifying Adult Dengue Patients at Low Risk for Clinically Significant Bleeding.
Autorzy:: Wong JG; Institute of Infectious Disease and Epidemiology, Tan Tock Seng Hospital, Singapore, Singapore.; Department of Clinical Epidemiology, Tan Tock Seng Hospital, Singapore, Singapore.
Thein TL; Institute of Infectious Disease and Epidemiology, Tan Tock Seng Hospital, Singapore, Singapore.
Leo YS; Institute of Infectious Disease and Epidemiology, Tan Tock Seng Hospital, Singapore, Singapore.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Pang J; Institute of Infectious Disease and Epidemiology, Tan Tock Seng Hospital, Singapore, Singapore.; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.
Lye DC; Institute of Infectious Disease and Epidemiology, Tan Tock Seng Hospital, Singapore, Singapore.; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2016 Feb 05; Vol. 11 (2), pp. e0148579. Date of Electronic Publication: 2016 Feb 05 (Print Publication: 2016).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Dengue/*complications
Hemorrhage/*etiology
Adolescent ; Adult ; Cohort Studies ; Dengue/mortality ; Female ; Humans ; Male ; Menorrhagia/etiology ; Middle Aged ; Multivariate Analysis ; Platelet Count ; Retrospective Studies ; Risk Factors ; Severe Dengue/complications ; Severe Dengue/mortality ; Vomiting/etiology ; Young Adult

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Skocz do pozycji: 18.

Tytuł:: A prospective case-control study to investigate retinal microvascular changes in acute dengue infection.
Autorzy:: Tan P; National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore.; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.
Lye DC; Institute of Infectious Diseases and Epidemiology, Communicable Diseases Centre, Tan Tock Seng Hospital, Singapore.; Yong Loo Lin School of Medicine, National University of Singapore.
Yeo TK; National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore.
Cheung CY; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.; Ophthalmology and Visual Sciences Academic Clinical Programme, Duke-NUS Graduate Medical School, National University of Singapore, Singapore.
Thein TL; Institute of Infectious Diseases and Epidemiology, Communicable Diseases Centre, Tan Tock Seng Hospital, Singapore.
Wong JG; Institute of Infectious Diseases and Epidemiology, Communicable Diseases Centre, Tan Tock Seng Hospital, Singapore.
Agrawal R; National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore.; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.
Li LJ; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.; Ophthalmology and Visual Sciences Academic Clinical Programme, Duke-NUS Graduate Medical School, National University of Singapore, Singapore.
Wong TY; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.; Ophthalmology and Visual Sciences Academic Clinical Programme, Duke-NUS Graduate Medical School, National University of Singapore, Singapore.
Gan VC; Institute of Infectious Diseases and Epidemiology, Communicable Diseases Centre, Tan Tock Seng Hospital, Singapore.
Leo YS; Institute of Infectious Diseases and Epidemiology, Communicable Diseases Centre, Tan Tock Seng Hospital, Singapore.; Yong Loo Lin School of Medicine, National University of Singapore.; Saw Swee Hock School of Public Health, National University of Singapore.
Teoh SC; National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore.; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.; Eagle Eye Center, Singapore.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2015 Nov 25; Vol. 5, pp. 17183. Date of Electronic Publication: 2015 Nov 25.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Dengue/*physiopathology
Microvessels/*physiopathology
Retina/*physiopathology
Acute Disease ; Adult ; Aspartate Aminotransferases/metabolism ; Case-Control Studies ; Creatinine/blood ; Dengue/diagnosis ; Female ; Hematocrit ; Hemoglobins/analysis ; Humans ; Male ; Microcirculation ; Prospective Studies

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Skocz do pozycji: 19.

Tytuł:: Clinical outcome and genetic differences within a monophyletic Dengue virus type 2 population.
Autorzy:: Hapuarachchi HC; Environmental Health Institute, National Environment Agency, 11 Biopolis Way, #06-05-08, Singapore 138667.
Chua RC; Environmental Health Institute, National Environment Agency, 11 Biopolis Way, #06-05-08, Singapore 138667.
Shi Y; Environmental Health Institute, National Environment Agency, 11 Biopolis Way, #06-05-08, Singapore 138667.
Thein TL; Institute of Infectious Diseases and Epidemiology, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore 308433.
Lee LK; Institute of Infectious Diseases and Epidemiology, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore 308433.
Lee KS; School of Life Sciences and Chemical Technology, Ngee Ann Polytechnic, 535 Clementi Road, Singapore 599489.
Lye DC; Institute of Infectious Diseases and Epidemiology, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore 308433.
Ng LC; Environmental Health Institute, National Environment Agency, 11 Biopolis Way, #06-05-08, Singapore 138667.
Leo YS; Institute of Infectious Diseases and Epidemiology, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore 308433.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2015 Mar 26; Vol. 10 (3), pp. e0121696. Date of Electronic Publication: 2015 Mar 26 (Print Publication: 2015).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Phylogeny*
Dengue/*virology
Dengue Virus/*genetics
3' Untranslated Regions/genetics ; Adolescent ; Adult ; Aged ; Amino Acid Substitution ; Cohort Studies ; Dengue/immunology ; Dengue Virus/immunology ; Dengue Virus/isolation & purification ; Epitopes, B-Lymphocyte/immunology ; Epitopes, T-Lymphocyte/immunology ; Humans ; Middle Aged ; Molecular Sequence Data ; Nucleic Acid Conformation ; RNA, Viral/genetics ; Treatment Outcome ; Young Adult

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Skocz do pozycji: 20.

Tytuł:: Early clinical and laboratory risk factors of intensive care unit requirement during 2004-2008 dengue epidemics in Singapore: a matched case-control study.
Autorzy:: Pang J; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore. Junxiong_.; Infectious Diseases, Genome Institute of Singapore, Singapore, Singapore. Junxiong_.; Communicable Disease Center, Institute of Infectious Diseases and Epidemiology, Tan Tock Seng Hospital, Singapore, Singapore. Junxiong_.
Thein TL; Communicable Disease Center, Institute of Infectious Diseases and Epidemiology, Tan Tock Seng Hospital, Singapore, Singapore. linn_thein_.
Leo YS; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore. yee_sin_.; Communicable Disease Center, Institute of Infectious Diseases and Epidemiology, Tan Tock Seng Hospital, Singapore, Singapore. yee_sin_.; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. yee_sin_.
Lye DC; Communicable Disease Center, Institute of Infectious Diseases and Epidemiology, Tan Tock Seng Hospital, Singapore, Singapore. david_.; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. david_.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore. david_.; Pokaż więcej
Źródło:: BMC infectious diseases [BMC Infect Dis] 2014 Dec 05; Vol. 14, pp. 649. Date of Electronic Publication: 2014 Dec 05.
Typ publikacji:: Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Epidemics*
Critical Care/*statistics & numerical data
Dengue/*therapy
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Decision Support Techniques ; Dengue/diagnosis ; Dengue/epidemiology ; Female ; Humans ; Intensive Care Units/statistics & numerical data ; Logistic Models ; Male ; Matched-Pair Analysis ; Middle Aged ; Multivariate Analysis ; Prognosis ; Retrospective Studies ; Risk Factors ; Sensitivity and Specificity ; Singapore/epidemiology ; Young Adult

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