- Tytuł:
-
Methionine restriction exposes a targetable redox vulnerability of triple-negative breast cancer cells by inducing
thioredoxin reductase. - Autorzy:
- Źródło:
- Breast cancer research and treatment [Breast Cancer Res Treat] 2021 Dec; Vol. 190 (3), pp. 373-387. Date of Electronic Publication: 2021 Sep 22.
- Typ publikacji:
- Journal Article
- MeSH Terms:
-
Thioredoxin -Disulfide Reductase*/geneticsThioredoxin -Disulfide Reductase*/metabolism
Triple Negative Breast Neoplasms*/drug therapy
Triple Negative Breast Neoplasms*/genetics
Animals ; Auranofin/pharmacology ; Humans ; Methionine/metabolism ; Mice ; Oxidation-Reduction ;Thioredoxin Reductase 1/genetics ;Thioredoxin Reductase 1/metabolism
Czasopismo naukowe