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Wyszukujesz frazę ""Thomas CN"" wg kryterium: Autor

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    Wyświetlanie 1-11 z 11
    Tytuł:
    Emerging therapies and their delivery for treating age-related macular degeneration.
    Autorzy:
    Thomas CN; School of Biomedical Sciences, Institute of Clinical Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
    Sim DA; Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, UK.; National Institute for Health Research (NIHR) Biomedical Research Centre at Moorfields Eye Hospital and University College London Institute of Ophthalmology, London, UK.
    Lee WH; Action Against AMD, London, UK.; Affordable Medicines Programme, Oxford Martin School, University of Oxford, Oxford, UK.
    Alfahad N; School of Biomedical Sciences, Institute of Clinical Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
    Dick AD; National Institute for Health Research (NIHR) Biomedical Research Centre at Moorfields Eye Hospital and University College London Institute of Ophthalmology, London, UK.; Academic Unit of Ophthalmology, Bristol Medical School and School of Cellular and Molecular Medicine, University of Bristol, Bristol, UK.
    Denniston AK; National Institute for Health Research (NIHR) Biomedical Research Centre at Moorfields Eye Hospital and University College London Institute of Ophthalmology, London, UK.; Academic Unit of Ophthalmology, Institute of Inflammation and Ageing, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.; Department of Ophthalmology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.; Centre for Patient Reported Outcome Research, Institute of Applied Health Research, University of Birmingham, Birmingham, UK.; Birmingham Health Partners Centre for Regulatory Science and Innovation, University of Birmingham, Birmingham, UK.; Health Data Research UK, London, UK.
    Hill LJ; School of Biomedical Sciences, Institute of Clinical Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
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    Źródło:
    British journal of pharmacology [Br J Pharmacol] 2022 May; Vol. 179 (9), pp. 1908-1937. Date of Electronic Publication: 2021 May 12.
    Typ publikacji:
    Journal Article; Review; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Angiogenesis Inhibitors*/therapeutic use
    Wet Macular Degeneration*/chemically induced
    Wet Macular Degeneration*/drug therapy
    Humans ; Intravitreal Injections ; Retina ; Vascular Endothelial Growth Factor A ; Visual Acuity
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Effects of intravitreal injection of siRNA against caspase-2 on retinal and optic nerve degeneration in air blast induced ocular trauma.
    Autorzy:
    Thomas CN; Neuroscience and Ophthalmology, Institute of Inflammation and Ageing, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.; School of Biomedical Sciences, Institute of Clinical Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
    Bernardo-Colón A; Vanderbilt Eye Institute, Vanderbilt University Medical Center, Nashville, TN, USA.
    Courtie E; Neuroscience and Ophthalmology, Institute of Inflammation and Ageing, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.; Ophthalmology Department, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
    Essex G; Neuroscience and Ophthalmology, Institute of Inflammation and Ageing, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
    Rex TS; Vanderbilt Eye Institute, Vanderbilt University Medical Center, Nashville, TN, USA.; Department of Ophthalmology and Visual Sciences, Vanderbilt University School of Medicine, Nashville, TN, USA.
    Blanch RJ; Neuroscience and Ophthalmology, Institute of Inflammation and Ageing, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK. .; Ophthalmology Department, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK. .; Academic Department of Military Surgery and Trauma, Royal Centre for Defence Medicine, Birmingham, UK. .; Centre for Trauma Sciences Research, University of Birmingham, Birmingham, B15 2TT, UK. .
    Ahmed Z; Neuroscience and Ophthalmology, Institute of Inflammation and Ageing, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK. .; Centre for Trauma Sciences Research, University of Birmingham, Birmingham, B15 2TT, UK. .
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    Źródło:
    Scientific reports [Sci Rep] 2021 Aug 19; Vol. 11 (1), pp. 16839. Date of Electronic Publication: 2021 Aug 19.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Air*
    Caspase 2/*metabolism
    Eye Injuries/*pathology
    Optic Nerve/*pathology
    RNA, Small Interfering/*administration & dosage
    Retina/*pathology
    Animals ; Axons/pathology ; Disease Models, Animal ; Green Fluorescent Proteins/metabolism ; Inflammation/pathology ; Intravitreal Injections ; Male ; Mice, Inbred C57BL ; Optic Nerve Injuries/pathology ; RNA-Binding Proteins/metabolism ; Retinal Ganglion Cells/pathology ; Vitreous Body/pathology ; Mice
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Norrin Protects Retinal Ganglion Cells from Excitotoxic Damage via the Induction of Leukemia Inhibitory Factor.
    Autorzy:
    Kassumeh S; Laboratory for Cell and Molecular Biology, Department of Ophthalmology, University Hospital, LMU Munich, 80336 Munich, Germany.
    Leopold S; Institute of Human Anatomy and Embryology, University of Regensburg, 93053 Regensburg, Germany.
    Fuchshofer R; Institute of Human Anatomy and Embryology, University of Regensburg, 93053 Regensburg, Germany.
    Thomas CN; Wellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
    Priglinger SG; Laboratory for Cell and Molecular Biology, Department of Ophthalmology, University Hospital, LMU Munich, 80336 Munich, Germany.
    Tamm ER; Institute of Human Anatomy and Embryology, University of Regensburg, 93053 Regensburg, Germany.
    Ohlmann A; Laboratory for Cell and Molecular Biology, Department of Ophthalmology, University Hospital, LMU Munich, 80336 Munich, Germany.; Institute of Human Anatomy and Embryology, University of Regensburg, 93053 Regensburg, Germany.
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    Źródło:
    Cells [Cells] 2020 Jan 23; Vol. 9 (2). Date of Electronic Publication: 2020 Jan 23.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Eye Proteins/*pharmacology
    Leukemia Inhibitory Factor/*metabolism
    Nerve Tissue Proteins/*pharmacology
    Neuroprotection/*drug effects
    Neurotoxins/*toxicity
    Retinal Ganglion Cells/*pathology
    Animals ; Endothelin-2/metabolism ; Ependymoglial Cells/drug effects ; Ependymoglial Cells/pathology ; Eye Proteins/metabolism ; Fibroblast Growth Factor 2/metabolism ; Gliosis/pathology ; Humans ; Leukemia Inhibitory Factor/deficiency ; Mice, Inbred C57BL ; N-Methylaspartate/pharmacology ; Nerve Tissue Proteins/metabolism ; Optic Nerve/drug effects ; Optic Nerve/pathology ; Phenotype ; Retinal Ganglion Cells/drug effects ; Retinal Ganglion Cells/metabolism ; Retinal Neurons/drug effects ; Retinal Neurons/pathology ; Signal Transduction
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Retinal Ganglion Cells Die by Necroptotic Mechanisms in a Site-Specific Manner in a Rat Blunt Ocular Injury Model.
    Autorzy:
    Thomas CN; Neuroscience and Ophthalmology, Institute of Inflammation and Ageing, College of Medical and Dental Sciences, University of Birmingham, Birmingham B15 2TT, UK.; School of Biomedical Sciences, Institute of Clinical Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham B15 2TT, UK.
    Thompson AM; Neuroscience and Ophthalmology, Institute of Inflammation and Ageing, College of Medical and Dental Sciences, University of Birmingham, Birmingham B15 2TT, UK.
    Ahmed Z; Neuroscience and Ophthalmology, Institute of Inflammation and Ageing, College of Medical and Dental Sciences, University of Birmingham, Birmingham B15 2TT, UK.
    Blanch RJ; Neuroscience and Ophthalmology, Institute of Inflammation and Ageing, College of Medical and Dental Sciences, University of Birmingham, Birmingham B15 2TT, UK.; Academic Department of Military Surgery and Trauma, Royal Centre for Defence Medicine, Birmingham B15 2TT, UK.; Department of Ophthalmology, University Hospitals Birmingham NHS Foundation Trust, Birmingham B15 2TT, UK.
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    Źródło:
    Cells [Cells] 2019 Nov 26; Vol. 8 (12). Date of Electronic Publication: 2019 Nov 26.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Necroptosis*
    Eye Injuries/*etiology
    Eye Injuries/*metabolism
    Retinal Ganglion Cells/*metabolism
    Animals ; Biomarkers ; Cell Survival ; Disease Models, Animal ; Eye Injuries/pathology ; Gene Expression ; Immunohistochemistry ; Protein Kinases/genetics ; Protein Kinases/metabolism ; Protein Serine-Threonine Kinases/genetics ; Protein Serine-Threonine Kinases/metabolism ; Protein Transport ; Rats ; Receptor-Interacting Protein Serine-Threonine Kinases ; Retinal Ganglion Cells/pathology ; Wounds, Nonpenetrating
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
      Wyświetlanie 1-11 z 11

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