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    Wyświetlanie 1-14 z 14
    Tytuł:
    Cerebrospinal fluid flow dynamics in Huntington's disease evaluated by phase contrast MRI.
    Autorzy:
    Rodrigues FB; UCL Huntington's Disease Centre, UCL Queen Square Institute of Neurology, University College London, London, UK.
    Byrne LM; UCL Huntington's Disease Centre, UCL Queen Square Institute of Neurology, University College London, London, UK.
    De Vita E; Neuroradiological Academic Unit, UCL Queen Square Institute of Neurology, University College London, London, UK.; Department of Biomedical Engineering, School of Biomedical Engineering and Imaging Sciences, King's College London, London, UK.
    Johnson EB; UCL Huntington's Disease Centre, UCL Queen Square Institute of Neurology, University College London, London, UK.
    Hobbs NZ; Ixico Plc, London, UK.
    Thornton JS; Neuroradiological Academic Unit, UCL Queen Square Institute of Neurology, University College London, London, UK.
    Scahill RI; UCL Huntington's Disease Centre, UCL Queen Square Institute of Neurology, University College London, London, UK.
    Wild EJ; UCL Huntington's Disease Centre, UCL Queen Square Institute of Neurology, University College London, London, UK.
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    Źródło:
    The European journal of neuroscience [Eur J Neurosci] 2019 Jun; Vol. 49 (12), pp. 1632-1639. Date of Electronic Publication: 2019 Feb 19.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Magnetic Resonance Imaging*
    Cerebrospinal Fluid/*diagnostic imaging
    Cerebrospinal Fluid/*physiology
    Huntington Disease/*diagnostic imaging
    Huntington Disease/*physiopathology
    Cross-Sectional Studies ; Female ; Humans ; Hydrodynamics ; Male ; Middle Aged ; Pilot Projects ; Prospective Studies
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Natural history of limb girdle muscular dystrophy R9 over 6 years: searching for trial endpoints.
    Autorzy:
    Murphy AP; The John Walton Muscular Dystrophy Research Centre Institute of Genetic Medicine Newcastle University Newcastle Hospitals NHS Foundation Trust Central Parkway Newcastle Upon Tyne United Kingdom NE1 4EP.
    Morrow J; Department of Molecular Neurosciences MRC Centre for Neuromuscular Diseases UCL Institute of Neurology London United Kingdom.
    Dahlqvist JR; Department of Neurology Copenhagen Neuromuscular Center Rigshospitalet University of Copenhagen Blegdamsvej 9 2100 Copenhagen Denmark.
    Stojkovic T; Institute of Myology AP6HP, G-H Pitié-Salpêtrière 47-83 boulevard de l'hôpital 75651 Paris Cedex 13 France.
    Willis TA; The Robert Jones and Agnes Hunt Orthopaedic Hospital Oswestry Shropshire United Kingdom.
    Sinclair CDJ; Department of Molecular Neurosciences MRC Centre for Neuromuscular Diseases UCL Institute of Neurology London United Kingdom.
    Wastling S; Department of Molecular Neurosciences MRC Centre for Neuromuscular Diseases UCL Institute of Neurology London United Kingdom.
    Yousry T; Department of Molecular Neurosciences MRC Centre for Neuromuscular Diseases UCL Institute of Neurology London United Kingdom.
    Hanna MS; Department of Molecular Neurosciences MRC Centre for Neuromuscular Diseases UCL Institute of Neurology London United Kingdom.
    James MK; The John Walton Muscular Dystrophy Research Centre Institute of Genetic Medicine Newcastle University Newcastle Hospitals NHS Foundation Trust Central Parkway Newcastle Upon Tyne United Kingdom NE1 4EP.
    Mayhew A; The John Walton Muscular Dystrophy Research Centre Institute of Genetic Medicine Newcastle University Newcastle Hospitals NHS Foundation Trust Central Parkway Newcastle Upon Tyne United Kingdom NE1 4EP.
    Eagle M; The John Walton Muscular Dystrophy Research Centre Institute of Genetic Medicine Newcastle University Newcastle Hospitals NHS Foundation Trust Central Parkway Newcastle Upon Tyne United Kingdom NE1 4EP.
    Lee LE; Department of Molecular Neurosciences MRC Centre for Neuromuscular Diseases UCL Institute of Neurology London United Kingdom.
    Hogrel JY; Institute of Myology Neuromuscular Investigation Center Pitié-Salpêtrière Hospital Paris France.
    Carlier PG; Institute of Myology Neuromuscular Investigation Center Pitié-Salpêtrière Hospital Paris France.
    Thornton JS; Department of Molecular Neurosciences MRC Centre for Neuromuscular Diseases UCL Institute of Neurology London United Kingdom.
    Vissing J; Department of Neurology Copenhagen Neuromuscular Center Rigshospitalet University of Copenhagen Blegdamsvej 9 2100 Copenhagen Denmark.
    Hollingsworth KG; Newcastle Magnetic Resonance Centre Institute of Cellular Medicine Newcastle University Newcastle upon Tyne United Kingdom.
    Straub V; The John Walton Muscular Dystrophy Research Centre Institute of Genetic Medicine Newcastle University Newcastle Hospitals NHS Foundation Trust Central Parkway Newcastle Upon Tyne United Kingdom NE1 4EP.
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    Źródło:
    Annals of clinical and translational neurology [Ann Clin Transl Neurol] 2019 May 16; Vol. 6 (6), pp. 1033-1045. Date of Electronic Publication: 2019 May 16 (Print Publication: 2019).
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Muscle, Skeletal/*physiopathology
    Muscular Dystrophies, Limb-Girdle/*physiopathology
    Adult ; Cohort Studies ; Disease Progression ; Female ; Humans ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Outcome Assessment, Health Care
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Upper Limb Evaluation in Duchenne Muscular Dystrophy: Fat-Water Quantification by MRI, Muscle Force and Function Define Endpoints for Clinical Trials.
    Autorzy:
    Ricotti V; Dubowitz Neuromuscular Centre, UCL Institute of Child Health and Great Ormond Street Hospital, London, United Kingdom.
    Evans MR; MRC Centre for Neuromuscular Diseases, UCL Institute of Neurology, London, United Kingdom.; Neuroradiological Academic Unit, UCL Institute of Neurology, London, United Kingdom.
    Sinclair CD; MRC Centre for Neuromuscular Diseases, UCL Institute of Neurology, London, United Kingdom.; Neuroradiological Academic Unit, UCL Institute of Neurology, London, United Kingdom.
    Butler JW; Dubowitz Neuromuscular Centre, UCL Institute of Child Health and Great Ormond Street Hospital, London, United Kingdom.
    Ridout DA; Population, Policy and Practice Programme, UCL Institute of Child Health and Great Ormond Street Hospital, London, United Kingdom.
    Hogrel JY; Institut de Myologie, GH Pitié-Salpêtrière, Paris, France.
    Emira A; MRC Centre for Neuromuscular Diseases, UCL Institute of Neurology, London, United Kingdom.; Neuroradiological Academic Unit, UCL Institute of Neurology, London, United Kingdom.
    Morrow JM; MRC Centre for Neuromuscular Diseases, UCL Institute of Neurology, London, United Kingdom.
    Reilly MM; MRC Centre for Neuromuscular Diseases, UCL Institute of Neurology, London, United Kingdom.
    Hanna MG; MRC Centre for Neuromuscular Diseases, UCL Institute of Neurology, London, United Kingdom.
    Janiczek RL; GlaxoSmithKline, London, United Kingdom.
    Matthews PM; MRC Centre for Neuromuscular Diseases, UCL Institute of Neurology, London, United Kingdom.; Division of Brain Sciences and Centre for Neurotechnology, Imperial College London, United Kingdom.
    Yousry TA; MRC Centre for Neuromuscular Diseases, UCL Institute of Neurology, London, United Kingdom.; Neuroradiological Academic Unit, UCL Institute of Neurology, London, United Kingdom.
    Muntoni F; Dubowitz Neuromuscular Centre, UCL Institute of Child Health and Great Ormond Street Hospital, London, United Kingdom.; MRC Centre for Neuromuscular Diseases, UCL Institute of Neurology, London, United Kingdom.
    Thornton JS; MRC Centre for Neuromuscular Diseases, UCL Institute of Neurology, London, United Kingdom.; Neuroradiological Academic Unit, UCL Institute of Neurology, London, United Kingdom.
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    Źródło:
    PloS one [PLoS One] 2016 Sep 20; Vol. 11 (9), pp. e0162542. Date of Electronic Publication: 2016 Sep 20 (Print Publication: 2016).
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Magnetic Resonance Imaging/*methods
    Muscle, Skeletal/*diagnostic imaging
    Muscular Dystrophy, Duchenne/*diagnostic imaging
    Upper Extremity/*diagnostic imaging
    Adolescent ; Child ; Fats/metabolism ; Forearm/diagnostic imaging ; Forearm/physiopathology ; Humans ; Longitudinal Studies ; Male ; Muscle Strength/physiology ; Muscle, Skeletal/metabolism ; Muscle, Skeletal/physiopathology ; Muscular Dystrophy, Duchenne/drug therapy ; Muscular Dystrophy, Duchenne/physiopathology ; Time Factors ; Upper Extremity/physiopathology ; Water/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Quantitative magnetic resonance imaging in limb-girdle muscular dystrophy 2I: a multinational cross-sectional study.
    Autorzy:
    Willis TA; Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom ; The Robert Jones and Agnes Hunt Orthopaedic Hospital, Oswestry, Shropshire, United Kingdom.
    Hollingsworth KG; Newcastle Magnetic Resonance Centre, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom.
    Coombs A; Newcastle Magnetic Resonance Centre, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom.
    Sveen ML; Neuromuscular Research Unit, Department of Neurology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
    Andersen S; Neuromuscular Research Unit, Department of Neurology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
    Stojkovic T; Centre de Reference des Maladies Neuromusculaires Paris Est, Institut de Myologie Groupe Hospitalier Pitié-Salpêtrière, Paris, France.
    Eagle M; Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom.
    Mayhew A; Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom.
    de Sousa PL; Institut de Myologie Groupe Hospitalier Pitié-Salpêtrière, Paris, France.
    Dewar L; MRC Centre for Neuromuscular Diseases, Department of Molecular Neurosciences, UCL Institute of Neurology, London, United Kingdom.
    Morrow JM; MRC Centre for Neuromuscular Diseases, Department of Molecular Neurosciences, UCL Institute of Neurology, London, United Kingdom.
    Sinclair CD; MRC Centre for Neuromuscular Diseases, Department of Molecular Neurosciences, UCL Institute of Neurology, London, United Kingdom.
    Thornton JS; MRC Centre for Neuromuscular Diseases, Department of Molecular Neurosciences, UCL Institute of Neurology, London, United Kingdom.
    Bushby K; Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom.
    Lochmuller H; Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom.
    Hanna MG; MRC Centre for Neuromuscular Diseases, Department of Molecular Neurosciences, UCL Institute of Neurology, London, United Kingdom.
    Hogrel JY; Institut de Myologie Groupe Hospitalier Pitié-Salpêtrière, Paris, France.
    Carlier PG; Institut de Myologie Groupe Hospitalier Pitié-Salpêtrière, Paris, France.
    Vissing J; Neuromuscular Research Unit, Department of Neurology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
    Straub V; Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom.
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    Źródło:
    PloS one [PLoS One] 2014 Feb 28; Vol. 9 (2), pp. e90377. Date of Electronic Publication: 2014 Feb 28 (Print Publication: 2014).
    Typ publikacji:
    Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Adipose Tissue, White/*pathology
    Magnetic Resonance Imaging/*methods
    Muscle, Skeletal/*pathology
    Muscular Dystrophies, Limb-Girdle/*pathology
    Proteins/*genetics
    Adipose Tissue, White/metabolism ; Adolescent ; Adult ; Cross-Sectional Studies ; Europe ; Female ; Humans ; Image Processing, Computer-Assisted ; Male ; Middle Aged ; Muscle, Skeletal/metabolism ; Muscular Dystrophies, Limb-Girdle/genetics ; Mutation ; Pentosyltransferases ; Sex Factors
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Quantitative muscle MRI as an assessment tool for monitoring disease progression in LGMD2I: a multicentre longitudinal study.
    Autorzy:
    Willis TA; Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom.
    Hollingsworth KG
    Coombs A
    Sveen ML
    Andersen S
    Stojkovic T
    Eagle M
    Mayhew A
    de Sousa PL
    Dewar L
    Morrow JM
    Sinclair CD
    Thornton JS
    Bushby K
    Lochmüller H
    Hanna MG
    Hogrel JY
    Carlier PG
    Vissing J
    Straub V
    Pokaż więcej
    Źródło:
    PloS one [PLoS One] 2013 Aug 14; Vol. 8 (8), pp. e70993. Date of Electronic Publication: 2013 Aug 14 (Print Publication: 2013).
    Typ publikacji:
    Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Disease Progression*
    Magnetic Resonance Imaging*
    Muscles/*pathology
    Muscular Dystrophies, Limb-Girdle/*diagnosis
    Muscular Dystrophies, Limb-Girdle/*pathology
    Adipose Tissue/metabolism ; Adolescent ; Adult ; Female ; Follow-Up Studies ; Humans ; Image Interpretation, Computer-Assisted ; Longitudinal Studies ; Male ; Middle Aged ; Young Adult
    SCR Disease Name:
    Muscular Dystrophy, Limb-Girdle, Type 2I
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Therapeutic subthalamic nucleus deep brain stimulation reverses cortico-thalamic coupling during voluntary movements in Parkinson's disease.
    Autorzy:
    Kahan J; Sobell Department of Motor Neuroscience and Movement Disorders, UCL Institute of Neurology, London, United Kingdom. />Mancini L
    Urner M
    Friston K
    Hariz M
    Holl E
    White M
    Ruge D
    Jahanshahi M
    Boertien T
    Yousry T
    Thornton JS
    Limousin P
    Zrinzo L
    Foltynie T
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    Źródło:
    PloS one [PLoS One] 2012; Vol. 7 (12), pp. e50270. Date of Electronic Publication: 2012 Dec 26.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Deep Brain Stimulation*
    Electric Stimulation Therapy*
    Motor Cortex/*physiology
    Parkinson Disease/*therapy
    Subthalamic Nucleus/*physiology
    Adult ; Aged ; Bayes Theorem ; Humans ; Magnetic Resonance Imaging ; Middle Aged ; Parkinson Disease/pathology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
      Wyświetlanie 1-14 z 14

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