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Tytuł:
CD8 T cell tolerance results from eviction of immature autoreactive cells from the thymus.
Autorzy:
Badr ME; Experimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Zhang Z; Experimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Tai X; Experimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Singer A; Experimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
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Źródło:
Science (New York, N.Y.) [Science] 2023 Nov 03; Vol. 382 (6670), pp. 534-541. Date of Electronic Publication: 2023 Nov 02.
Typ publikacji:
Journal Article
MeSH Terms:
CD8-Positive T-Lymphocytes*/immunology
Thymus Gland*/cytology
Thymus Gland*/immunology
Clonal Deletion*
Peripheral Tolerance*
Animals ; Mice ; Mice, Transgenic ; Receptors, Antigen, T-Cell/genetics ; Receptors, Antigen, T-Cell/metabolism ; Transcription Factors/metabolism ; Male ; Female
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Proinflammatory IFNγ Is Produced by but Not Required for the Generation of Eomes Thymic Innate CD8 T Cells.
Autorzy:
Won HY; Experimental Immunology Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892, USA.
Liman N; Experimental Immunology Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892, USA.
Li C; Experimental Immunology Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892, USA.
Park JH; Experimental Immunology Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892, USA.
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Źródło:
Cells [Cells] 2023 Oct 11; Vol. 12 (20). Date of Electronic Publication: 2023 Oct 11.
Typ publikacji:
Journal Article; Research Support, N.I.H., Intramural
MeSH Terms:
Interleukin-4*
Thymus Gland*
Mice ; Animals ; CD8-Positive T-Lymphocytes ; Cytokines ; Mice, Transgenic ; Interferon-gamma ; T-Box Domain Proteins/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
HIV-1 Infection Results in Sphingosine-1-Phosphate Receptor 1 Dysregulation in the Human Thymus.
Autorzy:
Resop RS; Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, CA 90095, USA.; UCLA AIDS Institute and Center for AIDS Research, University of California, Los Angeles, CA 90095, USA.
Salvatore B; Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, CA 90095, USA.
Kim SJ; Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, CA 90095, USA.
Gordon BR; Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, CA 90095, USA.
Blom B; Amsterdam University Medical Centers, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
Vatakis DN; UCLA AIDS Institute and Center for AIDS Research, University of California, Los Angeles, CA 90095, USA.; Department of Medicine, Division of Hematology-Oncology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.
Uittenbogaart CH; Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, CA 90095, USA.; UCLA AIDS Institute and Center for AIDS Research, University of California, Los Angeles, CA 90095, USA.; Department of Pediatrics, David Geffen School of Medicine at UCLA, University of California, Los Angeles, CA 90095, USA.; Jonsson Comprehensive Cancer Center, University of California, Los Angeles, CA 90095, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Sep 08; Vol. 24 (18). Date of Electronic Publication: 2023 Sep 08.
Typ publikacji:
Journal Article
MeSH Terms:
HIV Infections*/metabolism
Sphingosine-1-Phosphate Receptors*/metabolism
Thymus Gland*
Animals ; Humans ; Mice ; HIV-1 ; Lysophospholipids/metabolism ; Thymocytes/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
CD1b glycoprotein, a crucial marker of thymocyte development during T cell maturation in cynomolgus monkeys.
Autorzy:
Choi SM; Graduate Course of Translational Medicine, Seoul National University College of Medicine, Seoul, 03080, Republic of Korea.
Park HJ; Graduate Course of Translational Medicine, Seoul National University College of Medicine, Seoul, 03080, Republic of Korea.
Choi EA; Graduate Course of Translational Medicine, Seoul National University College of Medicine, Seoul, 03080, Republic of Korea.
Jung KC; Transplantation Research Institute, Seoul National University College of Medicine, Seoul, 03080, Republic of Korea.; Department of Pathology, Seoul National University College of Medicine, Seoul, 03080, Republic of Korea.; Integrated Major in Innovative Medical Science, Seoul National University Graduate School, Seoul, 03080, Republic of Korea.
Lee JI; Transplantation Research Institute, Seoul National University College of Medicine, Seoul, 03080, Republic of Korea. .; Department of Medicine, Seoul National University College of Medicine, Seoul, 03080, Republic of Korea. .
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Źródło:
Scientific reports [Sci Rep] 2023 Sep 01; Vol. 13 (1), pp. 14388. Date of Electronic Publication: 2023 Sep 01.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Thymocytes*
Thymus Gland*
Animals ; Macaca fascicularis ; Cell Differentiation ; Glycoproteins
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Tox4 regulates transcriptional elongation and reinitiation during murine T cell development.
Autorzy:
Wang T; Sheng Yushou Center of Cell Biology and Immunology, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, 200240, China.
Zhao R; Sheng Yushou Center of Cell Biology and Immunology, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, 200240, China.; Department of Pathology, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, 200052, China.
Zhi J; Sheng Yushou Center of Cell Biology and Immunology, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, 200240, China.
Liu Z; Sheng Yushou Center of Cell Biology and Immunology, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, 200240, China.
Wu A; Sheng Yushou Center of Cell Biology and Immunology, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, 200240, China.
Yang Z; Sheng Yushou Center of Cell Biology and Immunology, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, 200240, China.; School of Pharmacy, Shanghai Jiao Tong University, Shanghai, 200240, China.
Wang W; State Key Laboratory of Genetic Engineering, Collaborative Innovation Center of Genetics and Development, Human Phenome Institute, Shanghai Engineering Research Center of Industrial Microorganisms, School of Life Sciences and Huashan Hospital, Fudan University, Shanghai, 200438, China.
Ni T; State Key Laboratory of Genetic Engineering, Collaborative Innovation Center of Genetics and Development, Human Phenome Institute, Shanghai Engineering Research Center of Industrial Microorganisms, School of Life Sciences and Huashan Hospital, Fudan University, Shanghai, 200438, China.
Jing L; School of Pharmacy, Shanghai Jiao Tong University, Shanghai, 200240, China.
Yu M; Sheng Yushou Center of Cell Biology and Immunology, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, 200240, China. .; Department of Pathology, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, 200052, China. .
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Źródło:
Communications biology [Commun Biol] 2023 Jun 07; Vol. 6 (1), pp. 613. Date of Electronic Publication: 2023 Jun 07.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
CD8-Positive T-Lymphocytes*
Thymus Gland*
Animals ; Mice ; Humans ; Cell Differentiation/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Analysis of thymic generation of shared T-cell receptor α repertoire associated with recognition of tumor antigens shows no preference for neoantigens over wild-type antigens.
Autorzy:
Mattila J; Research Programs Unit, Translational Immunology, Haartmaninkatu 3 (PL 21) 00014, and Medicum, University of Helsinki, Helsinki, Finland.
Sormunen S; Department of Computer Science, Aalto University, Espoo, Finland.
Heikkilä N; Research Programs Unit, Translational Immunology, Haartmaninkatu 3 (PL 21) 00014, and Medicum, University of Helsinki, Helsinki, Finland.; Faculty of Medicine, Center for Vaccinology, Department of Pathology and Immunology, University of Geneva, Geneva, Switzerland.
Mattila IP; Department of Pediatric Cardiac and Transplantation Surgery, Hospital for Children and Adolescents, Helsinki University Central Hospital, Helsinki, Finland.
Saramäki J; Department of Computer Science, Aalto University, Espoo, Finland.
Arstila TP; Research Programs Unit, Translational Immunology, Haartmaninkatu 3 (PL 21) 00014, and Medicum, University of Helsinki, Helsinki, Finland.
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Źródło:
Cancer medicine [Cancer Med] 2023 Jun; Vol. 12 (12), pp. 13486-13496. Date of Electronic Publication: 2023 Apr 28.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Thymus Gland*/immunology
Antigens, Neoplasm*/genetics
Antigens, Neoplasm*/immunology
Neoplasms*/genetics
Neoplasms*/immunology
Neoplasms*/therapy
Immune Tolerance*/genetics
Receptors, Antigen, T-Cell, alpha-beta*/genetics
Receptors, Antigen, T-Cell, alpha-beta*/immunology
Humans ; Mutation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The value of thymus and activation related chemokine immunohistochemistry in classic Hodgkin lymphoma diagnostics.
Autorzy:
Kilsdonk M; Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
Veldman C; Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
Rosati S; Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
Plattel W; Department of Haematology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
Diepstra A; Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
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Źródło:
Histopathology [Histopathology] 2023 Feb; Vol. 82 (3), pp. 495-503. Date of Electronic Publication: 2022 Nov 23.
Typ publikacji:
Journal Article
MeSH Terms:
Hodgkin Disease*/diagnosis
Hodgkin Disease*/pathology
Lymphadenopathy*/pathology
Thymus Gland*/immunology
Thymus Gland*/metabolism
Humans ; Chemokines/chemistry ; Chemokines/immunology ; Immunohistochemistry ; Reed-Sternberg Cells/pathology ; Tumor Microenvironment
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Depletion of Ly6G-Expressing Neutrophilic Cells Leads to Altered Peripheral T-Cell Homeostasis and Thymic Development in Neonatal Mice.
Autorzy:
Rühle J; Department of Neonatology, University of Tübingen, D-72076 Tübingen, Germany.
Ginzel M; Department of Pediatric and Adolescent Surgery, Paracelsus Medical University Hospital, A-5020 Salzburg, Austria.
Dietz S; Department of Neonatology, University of Tübingen, D-72076 Tübingen, Germany.; Department of Neonatology, Heidelberg University Children's Hospital, D-69120 Heidelberg, Germany.
Schwarz J; Department of Neonatology, University of Tübingen, D-72076 Tübingen, Germany.
Lajqi T; Department of Neonatology, Heidelberg University Children's Hospital, D-69120 Heidelberg, Germany.
Beer-Hammer S; Department of Pharmacology, Experimental Therapy and Toxicology, Institute of Experimental and Clinical Pharmacology and Pharmacogenomic and ICePhA, University of Tübingen, D-72074 Tübingen, Germany.
Poets CF; Department of Neonatology, University of Tübingen, D-72076 Tübingen, Germany.
Gille C; Department of Neonatology, Heidelberg University Children's Hospital, D-69120 Heidelberg, Germany.
Köstlin-Gille N; Department of Neonatology, University of Tübingen, D-72076 Tübingen, Germany.; Department of Neonatology, Heidelberg University Children's Hospital, D-69120 Heidelberg, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Apr 24; Vol. 24 (9). Date of Electronic Publication: 2023 Apr 24.
Typ publikacji:
Journal Article
MeSH Terms:
Adaptive Immunity*
Thymus Gland*/immunology
Neutrophils*/immunology
T-Lymphocytes*/immunology
Animals ; Female ; Humans ; Infant, Newborn ; Mice ; Pregnancy ; Animals, Newborn ; Infant, Premature ; Lactation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Thymic Exhaustion and Increased Immune Activation Are the Main Mechanisms Involved in Impaired Immunological Recovery of HIV-Positive Patients under ART.
Autorzy:
Dos Santos Guedes MC; Keizo Asami Institute (iLIKA), Federal University of Pernambuco-UFPE, Recife 50670-901, PE, Brazil.; Department of Genetics, Federal University of Pernambuco-UFPE, Recife 50670-901, PE, Brazil.
Carvalho-Silva WHV; Keizo Asami Institute (iLIKA), Federal University of Pernambuco-UFPE, Recife 50670-901, PE, Brazil.; Aggeu Magalhães Institute (IAM/FIOCRUZ), Recife 50740-465, PE, Brazil.
Andrade-Santos JL; Keizo Asami Institute (iLIKA), Federal University of Pernambuco-UFPE, Recife 50670-901, PE, Brazil.; Department of Genetics, Federal University of Pernambuco-UFPE, Recife 50670-901, PE, Brazil.
Brelaz-de-Castro MCA; Aggeu Magalhães Institute (IAM/FIOCRUZ), Recife 50740-465, PE, Brazil.; Vitória Academic Center (CAV), Federal University of Pernambuco-UFPE, Recife 55608-680, PE, Brazil.
Souto FO; Keizo Asami Institute (iLIKA), Federal University of Pernambuco-UFPE, Recife 50670-901, PE, Brazil.; Agreste Academic Center (CAA), Federal University of Pernambuco-UFPE, Recife 55014-900, PE, Brazil.
Guimarães RL; Keizo Asami Institute (iLIKA), Federal University of Pernambuco-UFPE, Recife 50670-901, PE, Brazil.; Department of Genetics, Federal University of Pernambuco-UFPE, Recife 50670-901, PE, Brazil.
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Źródło:
Viruses [Viruses] 2023 Feb 05; Vol. 15 (2). Date of Electronic Publication: 2023 Feb 05.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Thymus Gland*
HIV Infections*/drug therapy
Humans ; CD4-Positive T-Lymphocytes ; Cytokines ; Immunophenotyping
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Thymic-Epithelial-Cell-Dependent Microenvironment Influences Proliferation and Apoptosis of Leukemic Cells.
Autorzy:
Patel SK; Department of Molecular Medicine, Sapienza University of Rome, 00161 Roma, Italy.
Zhdanovskaya N; Department of Molecular Medicine, Sapienza University of Rome, 00161 Roma, Italy.
Sergio I; Department of Experimental Medicine, Sapienza University of Rome, 00161 Roma, Italy.
Cardinale A; Research Area of Hematology and Oncology, Cell and Gene Therapy, Bambino Gesù Children's Hospital, IRCCS, 00146 Rome, Italy.
Rosichini M; Research Area of Hematology and Oncology, Cell and Gene Therapy, Bambino Gesù Children's Hospital, IRCCS, 00146 Rome, Italy.
Varricchio C; Department of Molecular Medicine, Sapienza University of Rome, 00161 Roma, Italy.
Pace E; Department of Molecular Medicine, Sapienza University of Rome, 00161 Roma, Italy.
Capalbo C; Department of Molecular Medicine, Sapienza University of Rome, 00161 Roma, Italy.
Locatelli F; Research Area of Hematology and Oncology, Cell and Gene Therapy, Bambino Gesù Children's Hospital, IRCCS, 00146 Rome, Italy.; Department of Life Sciences and Public Health, Catholic University of the Sacred Heart, 12631 Rome, Italy.
Macone A; Department of Biochemical Sciences 'A. Rossi Fanelli', Sapienza University of Rome, 00161 Roma, Italy.
Velardi E; Research Area of Hematology and Oncology, Cell and Gene Therapy, Bambino Gesù Children's Hospital, IRCCS, 00146 Rome, Italy.
Palermo R; Department of Molecular Medicine, Sapienza University of Rome, 00161 Roma, Italy.
Felli MP; Department of Experimental Medicine, Sapienza University of Rome, 00161 Roma, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 24; Vol. 25 (3). Date of Electronic Publication: 2024 Jan 24.
Typ publikacji:
Journal Article
MeSH Terms:
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma*/metabolism
Leukemia, T-Cell*/metabolism
Humans ; Thymus Gland/metabolism ; Signal Transduction ; Epithelial Cells/metabolism ; Apoptosis ; Cell Proliferation ; Tumor Microenvironment
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Differential expression and localization of immunity-related factors in main immune organs of yak.
Autorzy:
Zou SN; Laboratory of Animal Anatomy & Tissue Embryology, Veterinary Medicine of college, Gansu Agricultural University, Lanzhou, PR China.
Cui Y; Laboratory of Animal Anatomy & Tissue Embryology, Veterinary Medicine of college, Gansu Agricultural University, Lanzhou, PR China.; Gansu Province Livestock Embryo Engineering Research Center, Veterinary Medicine of college, Gansu Agricultural University, Lanzhou, PR China.
Yu SJ; Gansu Province Livestock Embryo Engineering Research Center, Veterinary Medicine of college, Gansu Agricultural University, Lanzhou, PR China.
Pan YY; Gansu Province Livestock Embryo Engineering Research Center, Veterinary Medicine of college, Gansu Agricultural University, Lanzhou, PR China.
He JF; Laboratory of Animal Anatomy & Tissue Embryology, Veterinary Medicine of college, Gansu Agricultural University, Lanzhou, PR China.
Zhang Q; Laboratory of Animal Anatomy & Tissue Embryology, Veterinary Medicine of college, Gansu Agricultural University, Lanzhou, PR China.
Liao B; Laboratory of Animal Anatomy & Tissue Embryology, Veterinary Medicine of college, Gansu Agricultural University, Lanzhou, PR China.
Zhang J; Laboratory of Animal Anatomy & Tissue Embryology, Veterinary Medicine of college, Gansu Agricultural University, Lanzhou, PR China.
Zhang P; Laboratory of Animal Anatomy & Tissue Embryology, Veterinary Medicine of college, Gansu Agricultural University, Lanzhou, PR China.
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Źródło:
Animal biotechnology [Anim Biotechnol] 2023 Dec; Vol. 34 (8), pp. 3315-3328. Date of Electronic Publication: 2022 Nov 02.
Typ publikacji:
Journal Article
MeSH Terms:
Interleukin-17*/metabolism
Lymph Nodes*/metabolism
Cattle ; Animals ; Spleen ; T-Lymphocytes ; Thymus Gland
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Adenoid cystic carcinoma of the thymus gland.
Autorzy:
Shatila M; Department of Thoracic Surgery, University Hospitals Birmingham NHS Trust, Birmingham, UK.; Department of Cardiothoracic Surgery, Faculty of Medicine, Alexandria University Hospital, Alexandria, Egypt.
Hemead H; Department of Thoracic Surgery, University Hospitals Birmingham NHS Trust, Birmingham, UK.
Murukesh N; Department of Medical Oncology, Worcestershire Royal Hospitals NHS Trust, Worcester, UK.
Taniere P; Department of Cellular Histopathology, University Hospitals Birmingham, NHS Trust, Birmingham, UK.
Russell C; Department of Cellular Histopathology, University Hospitals Birmingham, NHS Trust, Birmingham, UK.
Menon A; Department of Thoracic Surgery, University Hospitals Birmingham NHS Trust, Birmingham, UK.
Patel AJ; Department of Thoracic Surgery, University Hospitals Birmingham NHS Trust, Birmingham, UK. .; Institute of Immunology and Immunotherapy, University of Birmingham, Vincent Drive, Edgbaston, B15 2TT, UK. .
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Źródło:
Journal of cardiothoracic surgery [J Cardiothorac Surg] 2023 Nov 09; Vol. 18 (1), pp. 307. Date of Electronic Publication: 2023 Nov 09.
Typ publikacji:
Case Reports; Journal Article
MeSH Terms:
Carcinoma, Adenoid Cystic*/diagnostic imaging
Carcinoma, Adenoid Cystic*/surgery
Adenocarcinoma*/pathology
Thymoma*/diagnosis
Thymoma*/surgery
Thymus Neoplasms*/diagnosis
Thymus Neoplasms*/surgery
Thymus Neoplasms*/pathology
Humans ; Thymus Gland
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Type of PaperY192 within the SH2 Domain of Lck Regulates TCR Signaling Downstream of PLC-γ1 and Thymic Selection.
Autorzy:
Kästle M; Institute of Molecular and Clinical Immunology, Medical Faculty, Otto-von-Guericke University, 39120 Magdeburg, Germany.
Merten C; Institute of Molecular and Clinical Immunology, Medical Faculty, Otto-von-Guericke University, 39120 Magdeburg, Germany.
Hartig R; Institute of Molecular and Clinical Immunology, Medical Faculty, Otto-von-Guericke University, 39120 Magdeburg, Germany.
Plaza-Sirvent C; Institute of Molecular and Clinical Immunology, Medical Faculty, Otto-von-Guericke University, 39120 Magdeburg, Germany.; Department of Molecular Immunology, Ruhr-University Bochum, 44801 Bochum, Germany.
Schmitz I; Institute of Molecular and Clinical Immunology, Medical Faculty, Otto-von-Guericke University, 39120 Magdeburg, Germany.; Department of Molecular Immunology, Ruhr-University Bochum, 44801 Bochum, Germany.
Bommhardt U; Institute of Molecular and Clinical Immunology, Medical Faculty, Otto-von-Guericke University, 39120 Magdeburg, Germany.; Health Campus Immunology, Infectiology and Inflammation (GC-I3), Medical Faculty, Otto-von-Guericke University, 39120 Magdeburg, Germany.; Center for Health and Medical Prevention (CHaMP), Otto-von-Guericke University, 39120 Magdeburg, Germany.
Schraven B; Institute of Molecular and Clinical Immunology, Medical Faculty, Otto-von-Guericke University, 39120 Magdeburg, Germany.; Health Campus Immunology, Infectiology and Inflammation (GC-I3), Medical Faculty, Otto-von-Guericke University, 39120 Magdeburg, Germany.; Center for Health and Medical Prevention (CHaMP), Otto-von-Guericke University, 39120 Magdeburg, Germany.
Simeoni L; Institute of Molecular and Clinical Immunology, Medical Faculty, Otto-von-Guericke University, 39120 Magdeburg, Germany.; Health Campus Immunology, Infectiology and Inflammation (GC-I3), Medical Faculty, Otto-von-Guericke University, 39120 Magdeburg, Germany.; Center for Health and Medical Prevention (CHaMP), Otto-von-Guericke University, 39120 Magdeburg, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Jun 30; Vol. 23 (13). Date of Electronic Publication: 2022 Jun 30.
Typ publikacji:
Journal Article
MeSH Terms:
Lymphocyte Specific Protein Tyrosine Kinase p56(lck)*/genetics
Lymphocyte Specific Protein Tyrosine Kinase p56(lck)*/metabolism
Phospholipase C gamma*/immunology
Receptors, Antigen, T-Cell*/immunology
Thymus Gland*/immunology
src-Family Kinases*/immunology
Animals ; Mice ; Phosphorylation ; Signal Transduction ; src Homology Domains
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Primary explants of the postnatal thymus allow the expansion of clonogenic thymic epithelial cells that constitute thymospheres.
Autorzy:
Ocampo-Godinez JM; Laboratorio de Bioingeniería de Tejidos, División de Estudios de Posgrado e Investigación, Universidad Nacional Autónoma de Mexico, Mexico City, Mexico.; Laboratorio de Genética, Departamento de Zoología, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Mexico City, Mexico.; Carrera de Médico Cirujano, Facultad de Estudios Superiores Iztacala, Universidad Nacional Autónoma de Mexico, Mexico City, Estado de Mexico, Mexico.; Laboratorio de Inmunoquímica I, Departamento de Inmunología, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Mexico City, Mexico.
Gonzalez-Quiroz JL; Laboratorio de Inmunoquímica I, Departamento de Inmunología, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Mexico City, Mexico.
Cote-Palafox H; Carrera de Médico Cirujano, Facultad de Estudios Superiores Iztacala, Universidad Nacional Autónoma de Mexico, Mexico City, Estado de Mexico, Mexico.
George E; Carrera de Médico Cirujano, Facultad de Estudios Superiores Iztacala, Universidad Nacional Autónoma de Mexico, Mexico City, Estado de Mexico, Mexico.
Vergara-Lope Nuñez JA; Laboratorio de Bioingeniería de Tejidos, División de Estudios de Posgrado e Investigación, Universidad Nacional Autónoma de Mexico, Mexico City, Mexico.; Central de Microscopia, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Mexico City, Mexico.
Villagomez-Olea G; Laboratorio de Bioingeniería de Tejidos, División de Estudios de Posgrado e Investigación, Universidad Nacional Autónoma de Mexico, Mexico City, Mexico.
Vazquez-Vazquez FC; Laboratorio de Investigación de Materiales Dentales y Biomateriales, Departamento de Estudios de Posgrado e Investigación, Universidad Nacional Autónoma de México, Mexico City, Mexico.
Lopez-Villegas EO; Central de Microscopia, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Mexico City, Mexico.
Leon-Avila G; Carrera de Médico Cirujano, Facultad de Estudios Superiores Iztacala, Universidad Nacional Autónoma de Mexico, Mexico City, Estado de Mexico, Mexico.
Dominguez-Lopez ML; Laboratorio de Inmunoquímica I, Departamento de Inmunología, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Mexico City, Mexico. .
Alvarez-Perez MA; Laboratorio de Bioingeniería de Tejidos, División de Estudios de Posgrado e Investigación, Universidad Nacional Autónoma de Mexico, Mexico City, Mexico. .
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Źródło:
Stem cell research & therapy [Stem Cell Res Ther] 2023 Oct 31; Vol. 14 (1), pp. 312. Date of Electronic Publication: 2023 Oct 31.
Typ publikacji:
Journal Article
MeSH Terms:
Immunity, Innate*
Lymphocytes*
Mice ; Animals ; Thymus Gland/metabolism ; Epithelial Cells/metabolism ; T-Lymphocytes ; Cell Differentiation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Zeb2 regulates differentiation of long-lived effector of invariant natural killer T cells.
Autorzy:
Iyoda T; Laboratory for Immunotherapy, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Kanagawa, Japan.
Shimizu K; Laboratory for Immunotherapy, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Kanagawa, Japan.; Program for Drug Discovery and Medical Technology Platforms, RIKEN, Yokohama, Kanagawa, Japan.
Endo T; Laboratory for Integrative Genomics, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Kanagawa, Japan.
Watanabe T; Laboratory for Integrative Genomics, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Kanagawa, Japan.
Taniuchi I; Laboratory for Transcriptional Regulation, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Kanagawa, Japan.
Aoshima H; Laboratory for Immunotherapy, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Kanagawa, Japan.
Satoh M; Laboratory for Immunotherapy, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Kanagawa, Japan.
Nakazato H; Laboratory for Immunotherapy, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Kanagawa, Japan.
Yamasaki S; Laboratory for Immunotherapy, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Kanagawa, Japan.
Fujii SI; Laboratory for Immunotherapy, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Kanagawa, Japan. .; Program for Drug Discovery and Medical Technology Platforms, RIKEN, Yokohama, Kanagawa, Japan. .
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Źródło:
Communications biology [Commun Biol] 2023 Oct 30; Vol. 6 (1), pp. 1070. Date of Electronic Publication: 2023 Oct 30.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Natural Killer T-Cells*
Cell Differentiation ; Gene Expression Regulation ; Transcription Factors ; Thymus Gland
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Human thymic putative CD8αα precursors exhibit a biased TCR repertoire in single cell AIRR-seq.
Autorzy:
Heimli M; Department of Medical Genetics, University of Oslo and Oslo University Hospital, 0424, Oslo, Norway.
Tennebø Flåm S; Department of Medical Genetics, University of Oslo and Oslo University Hospital, 0424, Oslo, Norway.
Sagsveen Hjorthaug H; Department of Medical Genetics, University of Oslo and Oslo University Hospital, 0424, Oslo, Norway.
Bjørnstad PM; Department of Medical Genetics, University of Oslo and Oslo University Hospital, 0424, Oslo, Norway.
Chernigovskaya M; Department of Immunology, University of Oslo and Oslo University Hospital, 0372, Oslo, Norway.
Le QK; Department of Immunology, University of Oslo and Oslo University Hospital, 0372, Oslo, Norway.
Tekpli X; Department of Medical Genetics, University of Oslo and Oslo University Hospital, 0424, Oslo, Norway.
Greiff V; Department of Immunology, University of Oslo and Oslo University Hospital, 0372, Oslo, Norway.
Lie BA; Department of Medical Genetics, University of Oslo and Oslo University Hospital, 0424, Oslo, Norway. .
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Źródło:
Scientific reports [Sci Rep] 2023 Oct 18; Vol. 13 (1), pp. 17714. Date of Electronic Publication: 2023 Oct 18.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Receptors, Antigen, T-Cell*/metabolism
Thymocytes*/metabolism
Humans ; Child ; Thymus Gland/metabolism ; T-Lymphocytes, Regulatory ; Complementarity Determining Regions/genetics ; Complementarity Determining Regions/metabolism ; Cell Differentiation ; Receptors, Antigen, T-Cell, alpha-beta/genetics ; Receptors, Antigen, T-Cell, alpha-beta/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Primary unifocal thymic Rosai-Dorfman disease: an extremely rare challenge in diagnostic practice.
Autorzy:
Liu Q; Department of Pathology, Jiangxi Provincial People's Hospital, the First Affiliated Hospital of Nanchang Medical College, No. 152, Aiguo Road, Nanchang, 330006, China.
Liao F; Department of Nuclear medicine, Jiangxi Provincial People's Hospital, the First Affiliated Hospital of Nanchang Medical College, Nanchang, 330006, China.
Liu Y; Department of Pathology, Jiangxi Provincial People's Hospital, the First Affiliated Hospital of Nanchang Medical College, No. 152, Aiguo Road, Nanchang, 330006, China.
Cheng Y; Department of Pathology, Jiangxi Provincial People's Hospital, the First Affiliated Hospital of Nanchang Medical College, No. 152, Aiguo Road, Nanchang, 330006, China.
Qi C; Department of Pathology, Jiangxi Provincial People's Hospital, the First Affiliated Hospital of Nanchang Medical College, No. 152, Aiguo Road, Nanchang, 330006, China. .
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Źródło:
Journal of cardiothoracic surgery [J Cardiothorac Surg] 2023 Oct 10; Vol. 18 (1), pp. 284. Date of Electronic Publication: 2023 Oct 10.
Typ publikacji:
Case Reports; Journal Article
MeSH Terms:
Histiocytosis, Sinus*/diagnosis
Histiocytosis, Sinus*/surgery
Histiocytosis, Sinus*/pathology
Musculoskeletal Diseases*
Male ; Humans ; Middle Aged ; Histiocytes/metabolism ; Histiocytes/pathology ; Thymus Gland ; Lymphocytes/pathology ; Mediastinum/pathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Use of pediatric thymus to humanize mice for HIV-1 mucosal transmission.
Autorzy:
Roy CN; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Shu ST; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Kline C; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Rigatti L; Division of Laboratory Animal Resources, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Smithgall TE; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Ambrose Z; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. .
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Źródło:
Scientific reports [Sci Rep] 2023 Oct 10; Vol. 13 (1), pp. 17067. Date of Electronic Publication: 2023 Oct 10.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
HIV-1*
HIV Infections*
Mice ; Humans ; Animals ; Child ; Disease Models, Animal ; Thymus Gland/pathology ; CD4-Positive T-Lymphocytes ; Mice, SCID ; Mice, Inbred NOD
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The Protective Effects of Water-Soluble Alginic Acid on the N-Terminal of Thymopentin.
Autorzy:
Ji H; Center for Mitochondria and Healthy Aging, College of Life Sciences, Yantai University, Yantai 264005, China.
Fan Y; Center for Mitochondria and Healthy Aging, College of Life Sciences, Yantai University, Yantai 264005, China.
Gao X; Center for Mitochondria and Healthy Aging, College of Life Sciences, Yantai University, Yantai 264005, China.
Gong Y; Center for Mitochondria and Healthy Aging, College of Life Sciences, Yantai University, Yantai 264005, China.
Dai K; College of Food Science and Engineering, Tianjin University of Science and Technology, Tianjin 300457, China.
Wang Z; Center for Mitochondria and Healthy Aging, College of Life Sciences, Yantai University, Yantai 264005, China.
Xu B; Center for Mitochondria and Healthy Aging, College of Life Sciences, Yantai University, Yantai 264005, China.
Yu J; Center for Mitochondria and Healthy Aging, College of Life Sciences, Yantai University, Yantai 264005, China.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Sep 05; Vol. 28 (18). Date of Electronic Publication: 2023 Sep 05.
Typ publikacji:
Journal Article
MeSH Terms:
Thymopentin*/pharmacology
Thymopentin*/metabolism
Alginic Acid*
Humans ; Mice ; Animals ; Adjuvants, Immunologic/pharmacology ; T-Lymphocytes/metabolism ; Thymus Gland/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Liver Metastasis of Thymoma: Case Report and Review of the Literature.
Autorzy:
Mallick J; University of Texas Medical Branch, Galveston, TX, USA.
Peterson JM; University of Texas Medical Branch, Galveston, TX, USA.
Pina-Oviedo S; Duke University, Durham, NC, USA.
Patel N; University of Texas Medical Branch, Galveston, TX, USA.
Venkatesan R; University of Texas Medical Branch, Galveston, TX, USA.
Stevenson HL; University of Texas Medical Branch, Galveston, TX, USA.
Qiu S; University of Texas Medical Branch, Galveston, TX, USA.
Shen Y; University of Texas Medical Branch, Galveston, TX, USA.
Lyapichev KA; University of Texas Medical Branch, Galveston, TX, USA.
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Źródło:
International journal of surgical pathology [Int J Surg Pathol] 2023 Aug; Vol. 31 (5), pp. 755-760. Date of Electronic Publication: 2022 Oct 19.
Typ publikacji:
Review; Case Reports; Journal Article
MeSH Terms:
Thymoma*/surgery
Thymoma*/pathology
Thymus Neoplasms*/pathology
Liver Neoplasms*/pathology
Humans ; Prognosis ; Thymus Gland/pathology ; Neoplasm Staging
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 1-20 z 5247

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