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Wyszukujesz frazę ""Tissue Array Analysis"" wg kryterium: Temat


Tytuł :
The Application of the Tissue Microarray (TMA) Technology to Analyze Cerebral Organoids.
Autorzy :
Biunno I; Integrated Systems Engineering, Milano, Italy.; Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionale delle Ricerche, Milano, Italy.
Paiola E; Division of Anatomy Pathology, IRCCS MultiMedica, Milano, Italy.
De Blasio P; Integrated Systems Engineering, Milano, Italy.
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Źródło :
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society [J Histochem Cytochem] 2021 Jul; Vol. 69 (7), pp. 451-460. Date of Electronic Publication: 2021 Jun 18.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Tissue Array Analysis*
Brain/*cytology
Organoids/*cytology
Cell Differentiation ; Humans ; Induced Pluripotent Stem Cells/cytology ; Neurons/cytology
Czasopismo naukowe
Tytuł :
Highly Multiplexed Phenotyping of Immunoregulatory Proteins in the Tumor Microenvironment by CODEX Tissue Imaging.
Autorzy :
Phillips D; Department of Pathology, Stanford University School of Medicine, Stanford, CA, United States.; Department of Dermatology, Stanford University School of Medicine, Stanford, CA, United States.
Schürch CM; Department of Pathology, Stanford University School of Medicine, Stanford, CA, United States.; Department of Pathology and Neuropathology, University Hospital and Comprehensive Cancer Center Tübingen, Tübingen, Germany.
Khodadoust MS; Division of Oncology, Stanford University School of Medicine, Stanford, CA, United States.
Kim YH; Department of Dermatology, Stanford University School of Medicine, Stanford, CA, United States.; Division of Oncology, Stanford University School of Medicine, Stanford, CA, United States.
Nolan GP; Department of Pathology, Stanford University School of Medicine, Stanford, CA, United States.
Jiang S; Department of Pathology, Stanford University School of Medicine, Stanford, CA, United States.
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Źródło :
Frontiers in immunology [Front Immunol] 2021 May 19; Vol. 12, pp. 687673. Date of Electronic Publication: 2021 May 19 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Fluorescent Antibody Technique*
Single-Cell Analysis*
Tissue Array Analysis*
Tumor Microenvironment*
Biomarkers, Tumor/*analysis
Immune Checkpoint Proteins/*analysis
Lymphoma, T-Cell, Cutaneous/*immunology
Skin Neoplasms/*immunology
Clinical Decision-Making ; High-Throughput Screening Assays ; Humans ; Image Processing, Computer-Assisted ; Immune Checkpoint Inhibitors/therapeutic use ; Immunotherapy ; Lymphoma, T-Cell, Cutaneous/drug therapy ; Lymphoma, T-Cell, Cutaneous/pathology ; Microscopy, Fluorescence ; Predictive Value of Tests ; Skin Neoplasms/drug therapy ; Skin Neoplasms/pathology
Czasopismo naukowe
Tytuł :
Glycans unique to the relapse-prone subset within triple-negative breast cancer as revealed by lectin array-based analysis of surgical specimens.
Autorzy :
Sakata-Matsuzawa M; Department of Breast Oncology, Juntendo University School of Medicine, Tokyo, Japan.
Denda-Nagai K; Division of Glycobiologics, Intractable Disease Research Center, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Fujihira H; Division of Glycobiologics, Intractable Disease Research Center, Juntendo University Graduate School of Medicine, Tokyo, Japan.; Glycometabolic Biochemistry Laboratory, Cluster for Pioneering Research, RIKEN, Saitama, Japan.
Noji M; Division of Glycobiologics, Intractable Disease Research Center, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Ishii-Schrade KB; Division of Glycobiologics, Intractable Disease Research Center, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Matsuda A; Department of Biochemistry, Keio University School of Medicine, Tokyo, Japan.
Kuno A; Molecular & Cellular Glycoproteomics Research Group, Cellular and Molecular Biotechnology Research Institute, National Institute of Advanced Industrial Science & Technology, Tsukuba, Ibaraki, Japan.
Okazaki M; Department of Breast Oncology, Juntendo University School of Medicine, Tokyo, Japan.
Nakai K; Department of Breast Oncology, Juntendo University School of Medicine, Tokyo, Japan.
Horimoto Y; Department of Breast Oncology, Juntendo University School of Medicine, Tokyo, Japan.
Saito M; Department of Breast Oncology, Juntendo University School of Medicine, Tokyo, Japan.
Irimura T; Division of Glycobiologics, Intractable Disease Research Center, Juntendo University Graduate School of Medicine, Tokyo, Japan.
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Źródło :
PloS one [PLoS One] 2021 May 11; Vol. 16 (5), pp. e0250747. Date of Electronic Publication: 2021 May 11 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Tissue Array Analysis*
Polysaccharides/*metabolism
Triple Negative Breast Neoplasms/*metabolism
Triple Negative Breast Neoplasms/*surgery
Disease Susceptibility ; Humans ; Prognosis ; Recurrence ; Triple Negative Breast Neoplasms/pathology
Czasopismo naukowe
Tytuł :
Prenatal chromosome microarray: 'The UK experience'. A survey of reporting practices in UK genetic services (2012-2019).
Autorzy :
Patterson J; West of Scotland Centre for Genomic Medicine, Laboratory Medicine Building, QEUH, Glasgow, UK.
Wellesley D; Wessex Clinical Genetics Service, Princess Anne Hospital, Southampton, UK.
Morgan S; All Wales Genetics Laboratory, Institute of Medical Genetics, University Hospital of Wales Heath Park, Cardiff, UK.
Cilliers D; Oxford Centre for Genomic Medicine, ACE Building Nuffield Orthopaedic Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
Allen S; West Midlands Regional Genetics Laboratory, Birmingham Women's NHS Foundation Trust, Birmingham, UK.
Gardiner CA; West of Scotland Centre for Genomic Medicine, Laboratory Medicine Building, QEUH, Glasgow, UK.
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Corporate Authors :
Fetal Genomics Steering Group
UK Clinical Genetics Lead Clinician Group
UK Heads of Genetics Laboratory Group
Źródło :
Prenatal diagnosis [Prenat Diagn] 2021 May; Vol. 41 (6), pp. 661-667. Date of Electronic Publication: 2021 Apr 13.
Typ publikacji :
Journal Article
MeSH Terms :
Chromosomes/*genetics
Tissue Array Analysis/*methods
Adult ; Female ; Genetic Testing/methods ; Genetic Testing/statistics & numerical data ; Humans ; Pregnancy ; Prenatal Diagnosis/methods ; Surveys and Questionnaires ; Tissue Array Analysis/statistics & numerical data ; United Kingdom
Czasopismo naukowe
Tytuł :
Tissue Microarrays to Visualize Influenza D Attachment to Host Receptors in the Respiratory Tract of Farm Animals.
Autorzy :
Nemanichvili N; Department of Biomolecular Health Sciences, Division of Pathology, Faculty of Veterinary Medicine, Utrecht University, 3584 CL Utrecht, The Netherlands.
Berends AJ; Department of Biomolecular Health Sciences, Division of Pathology, Faculty of Veterinary Medicine, Utrecht University, 3584 CL Utrecht, The Netherlands.
Wubbolts RW; Department of Biomolecular Health Sciences, Division of Cell Biology, Metabolism & Cancer, Faculty of Veterinary Medicine, Utrecht University, 3584 CL Utrecht, The Netherlands.
Gröne A; Department of Biomolecular Health Sciences, Division of Pathology, Faculty of Veterinary Medicine, Utrecht University, 3584 CL Utrecht, The Netherlands.
Rijks JM; Dutch Wildlife Health Centre, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, 3584 CL Utrecht, The Netherlands.
de Vries RP; Department of Chemical Biology and Drug Discovery, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, 3584 CG Utrecht, The Netherlands.
Verheije MH; Department of Biomolecular Health Sciences, Division of Pathology, Faculty of Veterinary Medicine, Utrecht University, 3584 CL Utrecht, The Netherlands.
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Źródło :
Viruses [Viruses] 2021 Mar 31; Vol. 13 (4). Date of Electronic Publication: 2021 Mar 31.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Tissue Array Analysis*
Viral Tropism*
Virus Attachment*
Hemagglutinins, Viral/*metabolism
Respiratory System/*virology
Thogotovirus/*physiology
Viral Fusion Proteins/*metabolism
Animals ; Animals, Domestic/virology ; Cattle ; Goats ; Hemagglutinins, Viral/genetics ; Horses ; Host Microbial Interactions ; Recombinant Proteins/metabolism ; Sheep ; Sialic Acids/metabolism ; Swine ; Thogotovirus/chemistry ; Thogotovirus/genetics ; Viral Fusion Proteins/genetics
Czasopismo naukowe
Tytuł :
Development of a functional salivary gland tissue chip with potential for high-content drug screening.
Autorzy :
Song Y; Department of Biomedical Engineering, University of Rochester, Rochester, NY, USA.; Center for Oral Biology, University of Rochester Medical Center, Rochester, NY, USA.
Uchida H; Center for Oral Biology, University of Rochester Medical Center, Rochester, NY, USA.; Department of Biomedical Genetics, University of Rochester Medical Center, Rochester, NY, USA.
Sharipol A; Department of Biomedical Engineering, University of Rochester, Rochester, NY, USA.; Center for Oral Biology, University of Rochester Medical Center, Rochester, NY, USA.
Piraino L; Department of Biomedical Engineering, University of Rochester, Rochester, NY, USA.; Center for Oral Biology, University of Rochester Medical Center, Rochester, NY, USA.; Department of Dermatology, University of Rochester Medical Center, Rochester, NY, USA.
Mereness JA; Department of Biomedical Engineering, University of Rochester, Rochester, NY, USA.; Center for Oral Biology, University of Rochester Medical Center, Rochester, NY, USA.; Department of Environmental Medicine, University of Rochester Medical Center, Rochester, NY, USA.
Ingalls MH; Center for Oral Biology, University of Rochester Medical Center, Rochester, NY, USA.; Department of Biomedical Genetics, University of Rochester Medical Center, Rochester, NY, USA.
Rebhahn J; David H. Smith Center for Vaccine Biology and Immunology, University of Rochester Medical Center, Rochester, NY, USA.
Newlands SD; Department of Otolaryngology, University of Rochester Medical Center, Rochester, NY, USA.; Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA.; Department of Neuroscience, University of Rochester Medical Center, Rochester, NY, USA.
DeLouise LA; Department of Biomedical Engineering, University of Rochester, Rochester, NY, USA.; Center for Oral Biology, University of Rochester Medical Center, Rochester, NY, USA.; Department of Dermatology, University of Rochester Medical Center, Rochester, NY, USA.; Materials Science Program, University of Rochester, Rochester, NY, USA.
Ovitt CE; Center for Oral Biology, University of Rochester Medical Center, Rochester, NY, USA.; Department of Biomedical Genetics, University of Rochester Medical Center, Rochester, NY, USA.; Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA.
Benoit DSW; Department of Biomedical Engineering, University of Rochester, Rochester, NY, USA. .; Center for Oral Biology, University of Rochester Medical Center, Rochester, NY, USA. .; Department of Biomedical Genetics, University of Rochester Medical Center, Rochester, NY, USA. .; Department of Environmental Medicine, University of Rochester Medical Center, Rochester, NY, USA. .; Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA. .; Materials Science Program, University of Rochester, Rochester, NY, USA. .; Department of Chemical Engineering, University of Rochester, Rochester, NY, USA. .; Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, NY, USA. .
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Źródło :
Communications biology [Commun Biol] 2021 Mar 19; Vol. 4 (1), pp. 361. Date of Electronic Publication: 2021 Mar 19.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Video-Audio Media
MeSH Terms :
Drug Evaluation, Preclinical*
High-Throughput Screening Assays*
Tissue Array Analysis*
Acinar Cells/*drug effects
Radiation Injuries/*prevention & control
Salivary Glands/*drug effects
Xerostomia/*prevention & control
Acinar Cells/metabolism ; Acinar Cells/radiation effects ; Animals ; Calcium Signaling/drug effects ; Cells, Cultured ; Female ; Humans ; Hydrogels ; Male ; Mice, Inbred C57BL ; Microbubbles ; Middle Aged ; Parotid Gland/drug effects ; Parotid Gland/metabolism ; Parotid Gland/radiation effects ; Phenotype ; Polyethylene Glycols/chemistry ; Radiation Injuries/etiology ; Radiation Injuries/metabolism ; Salivary Glands/metabolism ; Salivary Glands/radiation effects ; Xerostomia/etiology ; Xerostomia/metabolism
Czasopismo naukowe
Tytuł :
Cell Analysis on Microfluidics Combined with Mass Spectrometry.
Autorzy :
Zhang W; Department of Chemistry, Beijing Key Laboratory of Microanalytical Methods and Instrumentation, MOE Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology, Tsinghua University.
Zhang Q; Department of Chemistry, Beijing Key Laboratory of Microanalytical Methods and Instrumentation, MOE Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology, Tsinghua University.
Lin JM; Department of Chemistry, Beijing Key Laboratory of Microanalytical Methods and Instrumentation, MOE Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology, Tsinghua University.
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Źródło :
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry [Anal Sci] 2021 Feb 10; Vol. 37 (2), pp. 249-260. Date of Electronic Publication: 2020 Nov 06.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Tissue Array Analysis*
Cell Culture Techniques ; Humans ; Mass Spectrometry ; Microfluidic Analytical Techniques
Czasopismo naukowe
Tytuł :
MDM2 gene amplification as selection tool for innovative targeted approaches in PD-L1 positive or negative muscle-invasive urothelial bladder carcinoma.
Autorzy :
Brunelli M; Department of Diagnostics and Public Health, Pathology Unit, University and Hospital Trust of Verona, Verona, Italy .; Department of Diagnostics and Public Health, FISH Lab, University and Hospital Trust of Verona, Verona, Italy.
Tafuri A; Division of Urology, University and Hospital Trust of Verona, Verona, Italy.
Cima L; Department of Clinical Services, Pathology Unit, Santa Chiara Hospital, Trento, Italy.
Cerruto MA; Division of Urology, University and Hospital Trust of Verona, Verona, Italy.
Milella M; Division of Oncology, University and Hospital Trust of Verona, Verona, Italy.
Zivi A; Division of Oncology, University and Hospital Trust of Verona, Verona, Italy.
Buti S; Division of Oncology, University and Hospital Trust of Parma, Parma, Italy.
Bersanelli M; Division of Oncology, University and Hospital Trust of Parma, Parma, Italy.
Fornarini G; Division of Oncology, San Martino Hospital, Genova, Italy.
Vellone VG; Division of Oncology, San Martino Hospital, Genova, Italy.
Rebuzzi SE; Division of Oncology, San Martino Hospital, Genova, Italy.
Procopio G; Division of Oncology, IRCCS Foundation, Istituto Nazionale dei Tumori di Milano, Milano, Italy.
Verzoni E; Division of Oncology, IRCCS Foundation, Istituto Nazionale dei Tumori di Milano, Milano, Italy.
Bracarda S; Division of Oncology, Santa Maria Hospital, Terni, Italy.
Sabbatini R; Department of Oncology, Hematology & Respiratory Diseases, Division of Oncology, University of Modena & Reggio Emilia, Modena, Modena & Reggio Emilia, Italy.
Baldessari C; Department of Oncology, Hematology & Respiratory Diseases, Division of Oncology, University of Modena & Reggio Emilia, Modena, Modena & Reggio Emilia, Italy.
Eccher A; Department of Diagnostics and Public Health, Pathology Unit, University and Hospital Trust of Verona, Verona, Italy.
Passalacqua R; Division of Oncology, Hospital Trust of Cremona, Cremona, Italy.
Perrucci B; Division of Oncology, Hospital Trust of Cremona, Cremona, Italy.
Giganti MO; Division of Oncology, Hospital Trust of Cremona, Cremona, Italy.
Donini M; Division of Oncology, Hospital Trust of Cremona, Cremona, Italy.
Panni S; Division of Oncology, Hospital Trust of Cremona, Cremona, Italy.
Tucci M; Division of Oncology, Cardinal Massaia Hospital, Asti, Italy.
Prati V; Division of Oncology, Institute for Cancer Research and Treatment, Asl Cn2 Alba-Brà, Alba-Brà, Italy.
Ortega C; Division of Oncology, Institute for Cancer Research and Treatment, Asl Cn2 Alba-Brà, Alba-Brà, Italy.
Caliò A; Department of Diagnostics and Public Health, Pathology Unit, University and Hospital Trust of Verona, Verona, Italy.
Alongi F; Division of Radiotherapy, Ospedale SacroCuore di Negrar di Valpolicella, Negrar, Italy.
Munari E; Division of Pathology, Ospedale SacroCuore di Negrar di Valpolicella, Negrar, Italy.
Pappagallo G; Clinical Epidemiologist, Silea, Italy.
Iacovelli R; Policlinico Universitario Fondazione Andrea Gemelli, Rome, Italy.
Mosca A; Oncology, Candiolo Cancer Institute, IRCCS-FPO, Torino, Italy.
Porta C; Department of Biomedical Sciences and Human Oncology, University of Bari 'A.Moro', Bari, Italy.; Division of Medical Oncology, Policlinico Consorziale di Bari, Bari, Italy.
Martignoni G; Department of Diagnostics and Public Health, Pathology Unit, University and Hospital Trust of Verona, Verona, Italy.; Pathology Unit, Pederzoli Hospital, Italy.
Antonelli A; Division of Urology, University and Hospital Trust of Verona, Verona, Italy.
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Źródło :
Journal of clinical pathology [J Clin Pathol] 2022 Jan; Vol. 75 (1), pp. 39-44. Date of Electronic Publication: 2020 Nov 03.
Typ publikacji :
Journal Article
MeSH Terms :
B7-H1 Antigen/*metabolism
Proto-Oncogene Proteins c-mdm2/*genetics
Urinary Bladder Neoplasms/*genetics
Aged ; Aged, 80 and over ; B7-H1 Antigen/genetics ; Biomarkers/metabolism ; Female ; Gene Amplification ; Humans ; Immunohistochemistry ; In Situ Hybridization, Fluorescence ; Lymphatic Metastasis ; Male ; Middle Aged ; Muscles/pathology ; Phenotype ; Proto-Oncogene Proteins c-mdm2/metabolism ; Tissue Array Analysis ; Urinary Bladder/pathology ; Urinary Bladder Neoplasms/pathology ; Urothelium/pathology
Czasopismo naukowe
Tytuł :
DNA Methylation Array Identifies Golli-MBP as a Biomarker for Disease Severity in Childhood Atopic Dermatitis.
Autorzy :
Chen KD; Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan; Kawasaki Disease Center, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan; Institute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan; Liver Transplantation Center, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan; Department of Surgery, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.
Huang YH; Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan; Kawasaki Disease Center, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.
Guo MM; Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan; Kawasaki Disease Center, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.
Chang LS; Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan; Kawasaki Disease Center, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.
Chu CH; Department of Statistics, National Cheng-Kung University, Tainan, Taiwan; Institute of Statistics, National University of Kaohsiung, Kaohsiung, Taiwan.
Bu LF; Institute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan; Liver Transplantation Center, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan; Department of Surgery, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.
Chu CL; Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan; Kawasaki Disease Center, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.
Lee CH; Department of Dermatology, Kaohsiung Chang Gung Memorial Hospital, Taiwan.
Liu SF; Division of Pulmonary & Critical Care Medicine, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan; Department of Respiratory Therapy, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.
Kuo HC; Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan; Kawasaki Disease Center, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan; Division of Pulmonary & Critical Care Medicine, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan; Department of Respiratory Therapy, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan. Electronic address: .
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Źródło :
The Journal of investigative dermatology [J Invest Dermatol] 2022 Jan; Vol. 142 (1), pp. 104-113. Date of Electronic Publication: 2021 Jul 19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
CpG Islands/*genetics
Dermatitis, Atopic/*diagnosis
Myelin Basic Protein/*genetics
Biomarkers ; Child, Preschool ; Cohort Studies ; DNA Methylation ; Epigenesis, Genetic ; Female ; High-Throughput Nucleotide Sequencing ; Humans ; Immunoglobulin E/blood ; Male ; Severity of Illness Index ; Tissue Array Analysis
Czasopismo naukowe
Tytuł :
Intratumoral Foxp3 T cell infiltration determines poor prognosis and immunoevasive contexture in gastric cancer patients.
Autorzy :
Fei Y; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Fudan University, Shanghai, China.
Cao Y; Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Gu Y; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Fudan University, Shanghai, China.
Fang H; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Fudan University, Shanghai, China.
Chen Y; Department of Immunology, School of Basic Medical Sciences, Fudan University, Shanghai, 200032, China.
Wang J; Department of Gastric Surgery, Fudan University Shanghai Cancer Center, Shanghai, China.
Liu X; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Fudan University, Shanghai, China.
Lv K; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Fudan University, Shanghai, China.
He X; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Fudan University, Shanghai, China.
Lin C; Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Liu H; Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Li H; Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
He H; Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Li R; Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200032, China. .
Zhang H; Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200032, China. .
Zhang W; Department of Immunology, School of Basic Medical Sciences, Fudan University, Shanghai, 200032, China. .
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Źródło :
Cancer immunology, immunotherapy : CII [Cancer Immunol Immunother] 2022 Jan; Vol. 71 (1), pp. 1-11. Date of Electronic Publication: 2021 May 12.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation, Neoplastic*
Forkhead Transcription Factors/*biosynthesis
Nuclear Receptor Subfamily 1, Group F, Member 3/*biosynthesis
Stomach Neoplasms/*immunology
Stomach Neoplasms/*metabolism
T-Lymphocytes/*cytology
Aged ; Autoimmune Diseases/immunology ; CD8-Positive T-Lymphocytes/cytology ; Chemotherapy, Adjuvant ; Female ; Humans ; Kaplan-Meier Estimate ; Lymphocytes, Tumor-Infiltrating ; Male ; Middle Aged ; Prognosis ; Proportional Hazards Models ; Retrospective Studies ; Tissue Array Analysis ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Classification of colorectal tissue images from high throughput tissue microarrays by ensemble deep learning methods.
Autorzy :
Nguyen HG; Institute of Pathology, University of Bern, Murtenstrasse 31, 3008, Bern, Switzerland.
Blank A; Institute of Pathology, University of Bern, Murtenstrasse 31, 3008, Bern, Switzerland.; Institute of Pathology, Triemli City Hospital, Birmensdorferstrasse 497, 8063, Zurich, Switzerland.
Dawson HE; Institute of Pathology, University of Bern, Murtenstrasse 31, 3008, Bern, Switzerland.
Lugli A; Institute of Pathology, University of Bern, Murtenstrasse 31, 3008, Bern, Switzerland.
Zlobec I; Institute of Pathology, University of Bern, Murtenstrasse 31, 3008, Bern, Switzerland. .
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Źródło :
Scientific reports [Sci Rep] 2021 Jan 27; Vol. 11 (1), pp. 2371. Date of Electronic Publication: 2021 Jan 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Deep Learning*
Image Processing, Computer-Assisted*/methods
Immunohistochemistry*/methods
Tissue Array Analysis*/methods
Colorectal Neoplasms/*metabolism
Colorectal Neoplasms/*pathology
Algorithms ; Colorectal Neoplasms/etiology ; Computational Biology/methods ; Humans ; Reproducibility of Results
Czasopismo naukowe
Tytuł :
Novel Criteria for Intratumoral Budding with Prognostic Relevance for Colon Cancer and Its Histological Subtypes.
Autorzy :
Pour Farid P; Experimental Tumorpathology, University Hospital, Friedrich-Alexander-University of Erlangen-Nüremberg (FAU), 91054 Erlangen, Germany.; Institute of Pathology, University Hospital, Friedrich-Alexander-University of Erlangen-Nüremberg (FAU), 91054 Erlangen, Germany.; Comprehensive Cancer Center-EMN (CCC), University Hospital, Friedrich-Alexander-University of Erlangen-Nüremberg (FAU), 91054 Erlangen, Germany.
Eckstein M; Institute of Pathology, University Hospital, Friedrich-Alexander-University of Erlangen-Nüremberg (FAU), 91054 Erlangen, Germany.; Comprehensive Cancer Center-EMN (CCC), University Hospital, Friedrich-Alexander-University of Erlangen-Nüremberg (FAU), 91054 Erlangen, Germany.
Merkel S; Comprehensive Cancer Center-EMN (CCC), University Hospital, Friedrich-Alexander-University of Erlangen-Nüremberg (FAU), 91054 Erlangen, Germany.; Department of Surgery, University Hospital, Friedrich-Alexander-University of Erlangen-Nüremberg (FAU), 91054 Erlangen, Germany.
Grützmann R; Comprehensive Cancer Center-EMN (CCC), University Hospital, Friedrich-Alexander-University of Erlangen-Nüremberg (FAU), 91054 Erlangen, Germany.; Department of Surgery, University Hospital, Friedrich-Alexander-University of Erlangen-Nüremberg (FAU), 91054 Erlangen, Germany.
Hartmann A; Institute of Pathology, University Hospital, Friedrich-Alexander-University of Erlangen-Nüremberg (FAU), 91054 Erlangen, Germany.; Comprehensive Cancer Center-EMN (CCC), University Hospital, Friedrich-Alexander-University of Erlangen-Nüremberg (FAU), 91054 Erlangen, Germany.
Bruns V; Fraunhofer Institute for Integrated Circuits IIS, Am Wolfsmantel 33, 91058 Erlangen, Germany.
Benz M; Fraunhofer Institute for Integrated Circuits IIS, Am Wolfsmantel 33, 91058 Erlangen, Germany.
Schneider-Stock R; Experimental Tumorpathology, University Hospital, Friedrich-Alexander-University of Erlangen-Nüremberg (FAU), 91054 Erlangen, Germany.; Institute of Pathology, University Hospital, Friedrich-Alexander-University of Erlangen-Nüremberg (FAU), 91054 Erlangen, Germany.; Comprehensive Cancer Center-EMN (CCC), University Hospital, Friedrich-Alexander-University of Erlangen-Nüremberg (FAU), 91054 Erlangen, Germany.
Geppert CI; Institute of Pathology, University Hospital, Friedrich-Alexander-University of Erlangen-Nüremberg (FAU), 91054 Erlangen, Germany.; Comprehensive Cancer Center-EMN (CCC), University Hospital, Friedrich-Alexander-University of Erlangen-Nüremberg (FAU), 91054 Erlangen, Germany.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Dec 03; Vol. 22 (23). Date of Electronic Publication: 2021 Dec 03.
Typ publikacji :
Journal Article
MeSH Terms :
Adenocarcinoma, Mucinous/*pathology
Carcinoma, Medullary/*pathology
Carcinoma, Signet Ring Cell/*pathology
Colonic Neoplasms/*pathology
Adenocarcinoma, Mucinous/metabolism ; Biomarkers, Tumor/metabolism ; Carcinoma, Medullary/metabolism ; Carcinoma, Signet Ring Cell/metabolism ; Colonic Neoplasms/metabolism ; Disease Progression ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; Male ; Neoplasm Metastasis ; Neoplasm Staging ; Prognosis ; Survival Analysis ; Tissue Array Analysis
Czasopismo naukowe
Tytuł :
Insulin signaling, androgen receptor and PSMA immunohistochemical analysis by semi-automated tissue microarray in prostate cancer with diabetes (DIAMOND study).
Autorzy :
Broggi G; Department of Medical and Surgical Sciences and Advanced Technologies 'G. F. Ingrassia', Anatomic Pathology, University of Catania, 95123, Catania, Italy.
Lo Giudice A; Department of Surgery, Urology Section, University of Catania, Catania, Italy; Department of Urology, European Institute of Oncology, IRCCS, Milan, Italy.
Di Mauro M; Department of Surgery, Urology Section, University of Catania, Catania, Italy.
Pricoco E; Department of Surgery, Urology Section, University of Catania, Catania, Italy.
Piombino E; Department of Experimental Oncology, Mediterranean Institute of Oncology (IOM), 95029, Catania, Italy.
Ferro M; Department of Urology, European Institute of Oncology, IRCCS, Milan, Italy.
Caltabiano R; Department of Medical and Surgical Sciences and Advanced Technologies 'G. F. Ingrassia', Anatomic Pathology, University of Catania, 95123, Catania, Italy.
Morgia G; Department of Surgery, Urology Section, University of Catania, Catania, Italy; Department of Experimental Oncology, Mediterranean Institute of Oncology (IOM), 95029, Catania, Italy.
Russo GI; Department of Surgery, Urology Section, University of Catania, Catania, Italy. Electronic address: .
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Źródło :
Translational research : the journal of laboratory and clinical medicine [Transl Res] 2021 Dec; Vol. 238, pp. 25-35. Date of Electronic Publication: 2021 Jul 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antigens, Surface/*metabolism
Diabetes Mellitus/*metabolism
Glutamate Carboxypeptidase II/*metabolism
Prostatic Neoplasms/*metabolism
Receptors, Androgen/*metabolism
Aged ; Antigens, CD/metabolism ; Biomarkers, Tumor/analysis ; Biomarkers, Tumor/metabolism ; Diabetes Mellitus/blood ; Humans ; Immunohistochemistry ; Insulin/metabolism ; Kaplan-Meier Estimate ; Male ; Middle Aged ; Prostatic Neoplasms/mortality ; Prostatic Neoplasms/pathology ; Receptor, IGF Type 1/metabolism ; Receptor, Insulin/metabolism ; Retrospective Studies ; Tissue Array Analysis
Czasopismo naukowe
Tytuł :
Lack of expression of LMO2 clone SP51 identifies MYC rearrangements in aggressive large B-cell lymphomas.
Autorzy :
Vazquez I; Department of Pathology, Hospital del Mar, Institut Hospital del Mar d'Investigacions Mediques (IMIM), Barcelona, Spain.; Department of Ciencies Morfologiques, Universitat Autonoma de Barcelona, Barcelona, Spain.
Papaleo N; Department of Pathology, Hospital del Mar, Institut Hospital del Mar d'Investigacions Mediques (IMIM), Barcelona, Spain.; Department of Pathology, Consorci Hospitalari Parc Tauli, Sabadell, Spain.; Department of Health and Experimental Sciences, Universitat Pompeu Fabra, Barcelona, Spain.
Lop J; Department of Pathology, Hospital del Mar, Institut Hospital del Mar d'Investigacions Mediques (IMIM), Barcelona, Spain.
Puiggros A; Department of Pathology, Hospital del Mar, Institut Hospital del Mar d'Investigacions Mediques (IMIM), Barcelona, Spain.
Sanchez-Gonzalez B; Department of Hematology, Hospital del Mar, Institute Hospital del Mar d'Investigacions Mediques (IMIM), Barcelona, Spain.
Diez-Feijoo R; Department of Hematology, Hospital del Mar, Institute Hospital del Mar d'Investigacions Mediques (IMIM), Barcelona, Spain.
Gimeno E; Department of Hematology, Hospital del Mar, Institute Hospital del Mar d'Investigacions Mediques (IMIM), Barcelona, Spain.
Andrade-Campos M; Department of Hematology, Hospital del Mar, Institute Hospital del Mar d'Investigacions Mediques (IMIM), Barcelona, Spain.
Salar A; Department of Hematology, Hospital del Mar, Institute Hospital del Mar d'Investigacions Mediques (IMIM), Barcelona, Spain.
Espinet B; Department of Pathology, Hospital del Mar, Institut Hospital del Mar d'Investigacions Mediques (IMIM), Barcelona, Spain.
Salido M; Department of Pathology, Hospital del Mar, Institut Hospital del Mar d'Investigacions Mediques (IMIM), Barcelona, Spain.
Tapia G; Department of Pathology, Hospital Germans Trias I Pujol, Institut Germans Trias I Pujol (IGTP), Badalona, Spain.
Carreras J; Department of Pathology, School of Medicine, Tokai University, Isehara, Japan.
Ferrer A; Department of Pathology, Hospital del Mar, Institut Hospital del Mar d'Investigacions Mediques (IMIM), Barcelona, Spain.; Department of Health and Experimental Sciences, Universitat Pompeu Fabra, Barcelona, Spain.
Arenillas L; Department of Pathology, Hospital del Mar, Institut Hospital del Mar d'Investigacions Mediques (IMIM), Barcelona, Spain.
Calvo X; Department of Pathology, Hospital del Mar, Institut Hospital del Mar d'Investigacions Mediques (IMIM), Barcelona, Spain.
Colomo L; Department of Pathology, Hospital del Mar, Institut Hospital del Mar d'Investigacions Mediques (IMIM), Barcelona, Spain. .; Department of Health and Experimental Sciences, Universitat Pompeu Fabra, Barcelona, Spain. .
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Źródło :
Virchows Archiv : an international journal of pathology [Virchows Arch] 2021 Dec; Vol. 479 (6), pp. 1073-1078. Date of Electronic Publication: 2021 Apr 03.
Typ publikacji :
Journal Article
MeSH Terms :
Biomarkers, Tumor*/analysis
Biomarkers, Tumor*/deficiency
Gene Rearrangement*
Immunohistochemistry*
Adaptor Proteins, Signal Transducing/*deficiency
LIM Domain Proteins/*deficiency
Lymphoma, Large B-Cell, Diffuse/*chemistry
Lymphoma, Large B-Cell, Diffuse/*genetics
Proto-Oncogene Proteins/*deficiency
Proto-Oncogene Proteins c-myc/*genetics
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Child ; Child, Preschool ; Female ; Humans ; Lymphoma, Large B-Cell, Diffuse/pathology ; Male ; Middle Aged ; Neprilysin/analysis ; Predictive Value of Tests ; Prognosis ; Prospective Studies ; Reproducibility of Results ; Retrospective Studies ; Tissue Array Analysis ; Young Adult
Czasopismo naukowe
Tytuł :
xDEEP-MSI: Explainable Bias-Rejecting Microsatellite Instability Deep Learning System in Colorectal Cancer.
Autorzy :
Bustos A; AI Cancer Research Unit, MedBravo, 03560 Alicante, Spain.
Payá A; Pathology Department, Alicante University General Hospital (HGUA), 03010 Alicante, Spain.; Alicante Institute for Health and Biomedical Research (ISABIAL), 03010 Alicante, Spain.
Torrubia A; AI Cancer Research Unit, MedBravo, 03560 Alicante, Spain.
Jover R; Pathology Department, Alicante University General Hospital (HGUA), 03010 Alicante, Spain.; Alicante Institute for Health and Biomedical Research (ISABIAL), 03010 Alicante, Spain.
Llor X; Department of Medicine, Yale Cancer Center, Yale University, New Haven, CT 06511, USA.
Bessa X; Gastroenterology Department, Hospital del Mar Medical Research Institute (IMIM), 08003 Barcelona, Spain.
Castells A; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Gastroenterology Department, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Hospital Clinic, University of Barcelona, 08036 Barcelona, Spain.
Carracedo Á; Fundación Pública Gallega de Medicina Genómica (GMX), 15706 Santiago de Compostela, Spain.
Alenda C; Pathology Department, Alicante University General Hospital (HGUA), 03010 Alicante, Spain.; Alicante Institute for Health and Biomedical Research (ISABIAL), 03010 Alicante, Spain.
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Źródło :
Biomolecules [Biomolecules] 2021 Nov 29; Vol. 11 (12). Date of Electronic Publication: 2021 Nov 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Microsatellite Instability*
Colorectal Neoplasms/*genetics
Computational Biology/*methods
Adult ; Aged ; Aged, 80 and over ; Algorithms ; Bias ; Biomarkers, Tumor/genetics ; Deep Learning ; Female ; Humans ; Male ; Middle Aged ; Tissue Array Analysis
Czasopismo naukowe
Tytuł :
Utilizing digital pathology to quantify stromal caveolin-1 expression in malignant and benign ovarian tumors: Associations with clinicopathological parameters and clinical outcomes.
Autorzy :
Saeed-Vafa D; Department of Anatomic Pathology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.
Marchion DC; Tissue Core-Biospecimen Processing Laboratory, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.
McCarthy SM; Department of Anatomic Pathology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.
Hakam A; Department of Anatomic Pathology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.
Lopez A; Department of Anatomic Pathology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.
Wenham RM; Department of Gynecologic Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.
Apte SM; Department of Gynecologic Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.
Chen DT; Department of Biostatistics and Bioinformatics, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.
Magliocco AM; Department of Anatomic Pathology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.
Lancaster JM; Department of Gynecologic Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.
Reid BM; Department of Cancer Epidemiology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.
Permuth JB; Department of Cancer Epidemiology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.
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Źródło :
PloS one [PLoS One] 2021 Nov 23; Vol. 16 (11), pp. e0256615. Date of Electronic Publication: 2021 Nov 23 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Caveolin 1/*metabolism
Cystadenocarcinoma, Serous/*metabolism
Ovarian Neoplasms/*metabolism
Ovary/*metabolism
Stromal Cells/*metabolism
Adult ; Aged ; Aged, 80 and over ; Biomarkers, Tumor/metabolism ; Cystadenocarcinoma, Serous/mortality ; Cystadenocarcinoma, Serous/pathology ; Down-Regulation ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; Immunohistochemistry ; Middle Aged ; Neoplasm Staging ; Ovarian Neoplasms/mortality ; Ovarian Neoplasms/pathology ; Ovary/pathology ; Stromal Cells/pathology ; Survival Rate ; Tissue Array Analysis
Czasopismo naukowe
Tytuł :
CD146 immunohistochemical staining for the separation of benign from malignant mesothelial proliferations.
Autorzy :
Salisbury T; Department of Pathology, Vancouver General Hospital, JPPN 1401, 910 West 10th Ave, Vancouver, BC, V5Z 1M9, Canada.; Department of Pathology, University of British Columbia, Vancouver, BC, Canada.
Churg A; Department of Pathology, Vancouver General Hospital, JPPN 1401, 910 West 10th Ave, Vancouver, BC, V5Z 1M9, Canada. .; Department of Pathology, University of British Columbia, Vancouver, BC, Canada. .
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Źródło :
Virchows Archiv : an international journal of pathology [Virchows Arch] 2021 Nov; Vol. 479 (5), pp. 1047-1050. Date of Electronic Publication: 2021 Mar 15.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Cell Proliferation*
Immunohistochemistry*
Biomarkers, Tumor/*analysis
Mesothelioma, Malignant/*immunology
CD146 Antigen/analysis ; Diagnosis, Differential ; Humans ; Mesothelioma, Malignant/pathology ; Predictive Value of Tests ; Tissue Array Analysis
Czasopismo naukowe
Tytuł :
Donor-Specific Antibody Is Associated with Increased Expression of Rejection Transcripts in Renal Transplant Biopsies Classified as No Rejection.
Autorzy :
Madill-Thomsen KS; Alberta Transplant Applied Genomics Centre, Edmonton, Alberta, Canada.
Böhmig GA; Division of Nephrology and Dialysis, Department of Medicine III, Medical University of Vienna, Vienna, Austria.
Bromberg J; Departments of Surgery and Microbiology and Immunology, University of Maryland, Baltimore, Maryland.
Einecke G; Department of Nephrology, Hannover Medical School, Hannover, Germany.
Eskandary F; Division of Nephrology and Dialysis, Department of Medicine III, Medical University of Vienna, Vienna, Austria.
Gupta G; Division of Nephrology, Virginia Commonwealth University, Richmond, Virginia.
Hidalgo LG; Department of Surgery, University of Wisconsin, Madison, Wisconsin.
Myslak M; Pomeranian Medical University, Department of Clinical Interventions and Department of Nephrology and Kidney Transplantation, Samodzielny Publiczny Wojewodzki Szpital Zespolony, Szczecin, Poland.
Viklicky O; Department of Nephrology and Transplant Center, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.
Perkowska-Ptasinska A; Department of Pathology, Medical University of Warsaw, Warsaw, Poland.
Halloran PF; Alberta Transplant Applied Genomics Centre, Edmonton, Alberta, Canada .; Department of Medicine, Division of Nephrology and Transplant Immunology, University of Alberta, Edmonton, Alberta, Canada.
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Corporate Authors :
INTERCOMEX Investigators
Źródło :
Journal of the American Society of Nephrology : JASN [J Am Soc Nephrol] 2021 Nov; Vol. 32 (11), pp. 2743-2758. Date of Electronic Publication: 2021 Jul 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Kidney Transplantation*
Tissue Donors*
Graft Rejection/*genetics
HLA Antigens/*immunology
Isoantibodies/*immunology
Kidney/*pathology
Transplants/*pathology
Antibody Specificity ; Biopsy ; False Negative Reactions ; Gene Expression ; Graft Survival ; Principal Component Analysis ; Prospective Studies ; Survival Analysis ; Tissue Array Analysis ; Transcription, Genetic
Czasopismo naukowe

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