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Wyszukujesz frazę ""Tissue Array Analysis"" wg kryterium: Temat


Tytuł:
Tumor Heterogeneity Confounds Lymphocyte Metrics in Diagnostic Lung Cancer Biopsies.
Autorzy:
Elfving H; From the Department of Immunology, Genetics, and Pathology, Uppsala University, Uppsala, Sweden.
Thurfjell V; From the Department of Immunology, Genetics, and Pathology, Uppsala University, Uppsala, Sweden.
Mattsson JSM; From the Department of Immunology, Genetics, and Pathology, Uppsala University, Uppsala, Sweden.
Backman M; From the Department of Immunology, Genetics, and Pathology, Uppsala University, Uppsala, Sweden.
Strell C; From the Department of Immunology, Genetics, and Pathology, Uppsala University, Uppsala, Sweden.
Micke P; From the Department of Immunology, Genetics, and Pathology, Uppsala University, Uppsala, Sweden.
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Źródło:
Archives of pathology & laboratory medicine [Arch Pathol Lab Med] 2024 Jan 01; Vol. 148 (1), pp. e18-e24.
Typ publikacji:
Journal Article
MeSH Terms:
Lung Neoplasms*/diagnosis
Carcinoma, Non-Small-Cell Lung*/diagnosis
Humans ; Lymphocytes ; Biomarkers ; Biopsy/methods ; Biomarkers, Tumor ; Tissue Array Analysis/methods ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
Detection of MDM2 gene amplification on tissue microarray-based Fluorescence In-Situ Hybridization (FISH) in well-differentiated and dedifferentiated liposarcomas, displaying a wide morphological spectrum: A validation study at a tertiary cancer referral centre.
Autorzy:
Rekhi B; Department of Surgical Pathology; Division of Molecular Pathology and Translational Medicine, Homi Bhabha National Institute (HBNI) University, Mumbai, Maharashtra, India.
Karnik N; Department of Surgical Pathology; Division of Molecular Pathology and Translational Medicine, Homi Bhabha National Institute (HBNI) University, Mumbai, Maharashtra, India.
Agrawal R; Department of Surgical Pathology, Homi Bhabha National Institute (HBNI) University, Mumbai, Maharashtra, India.
Shetty O; Department of Division of Molecular Pathology and Translational Medicine, Homi Bhabha National Institute (HBNI) University, Mumbai, Maharashtra, India.
Patkar S; Department of Surgical Oncology, Gastrointestinal, Retroperitoneum, Tata Memorial Hospital, Homi Bhabha National Institute (HBNI) University, Mumbai, Maharashtra, India.
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Źródło:
Indian journal of pathology & microbiology [Indian J Pathol Microbiol] 2022 Jan-Mar; Vol. 65 (1), pp. 65-75.
Typ publikacji:
Journal Article; Validation Study
MeSH Terms:
In Situ Hybridization, Fluorescence/*methods
Liposarcoma/*genetics
Nucleic Acid Amplification Techniques/*methods
Proto-Oncogene Proteins c-mdm2/*genetics
Tissue Array Analysis/*methods
Adult ; Aged ; Biomarkers, Tumor/genetics ; Cell Dedifferentiation ; Female ; Humans ; Liposarcoma/classification ; Male ; Middle Aged ; Nucleic Acid Amplification Techniques/standards ; Soft Tissue Neoplasms/diagnosis ; Soft Tissue Neoplasms/genetics ; Tissue Array Analysis/standards
Czasopismo naukowe
Tytuł:
Glycans unique to the relapse-prone subset within triple-negative breast cancer as revealed by lectin array-based analysis of surgical specimens.
Autorzy:
Sakata-Matsuzawa M; Department of Breast Oncology, Juntendo University School of Medicine, Tokyo, Japan.
Denda-Nagai K; Division of Glycobiologics, Intractable Disease Research Center, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Fujihira H; Division of Glycobiologics, Intractable Disease Research Center, Juntendo University Graduate School of Medicine, Tokyo, Japan.; Glycometabolic Biochemistry Laboratory, Cluster for Pioneering Research, RIKEN, Saitama, Japan.
Noji M; Division of Glycobiologics, Intractable Disease Research Center, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Ishii-Schrade KB; Division of Glycobiologics, Intractable Disease Research Center, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Matsuda A; Department of Biochemistry, Keio University School of Medicine, Tokyo, Japan.
Kuno A; Molecular & Cellular Glycoproteomics Research Group, Cellular and Molecular Biotechnology Research Institute, National Institute of Advanced Industrial Science & Technology, Tsukuba, Ibaraki, Japan.
Okazaki M; Department of Breast Oncology, Juntendo University School of Medicine, Tokyo, Japan.
Nakai K; Department of Breast Oncology, Juntendo University School of Medicine, Tokyo, Japan.
Horimoto Y; Department of Breast Oncology, Juntendo University School of Medicine, Tokyo, Japan.
Saito M; Department of Breast Oncology, Juntendo University School of Medicine, Tokyo, Japan.
Irimura T; Division of Glycobiologics, Intractable Disease Research Center, Juntendo University Graduate School of Medicine, Tokyo, Japan.
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Źródło:
PloS one [PLoS One] 2021 May 11; Vol. 16 (5), pp. e0250747. Date of Electronic Publication: 2021 May 11 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Tissue Array Analysis*
Polysaccharides/*metabolism
Triple Negative Breast Neoplasms/*metabolism
Triple Negative Breast Neoplasms/*surgery
Disease Susceptibility ; Humans ; Prognosis ; Recurrence ; Triple Negative Breast Neoplasms/pathology
Czasopismo naukowe
Tytuł:
Tissue Microarrays to Visualize Influenza D Attachment to Host Receptors in the Respiratory Tract of Farm Animals.
Autorzy:
Nemanichvili N; Department of Biomolecular Health Sciences, Division of Pathology, Faculty of Veterinary Medicine, Utrecht University, 3584 CL Utrecht, The Netherlands.
Berends AJ; Department of Biomolecular Health Sciences, Division of Pathology, Faculty of Veterinary Medicine, Utrecht University, 3584 CL Utrecht, The Netherlands.
Wubbolts RW; Department of Biomolecular Health Sciences, Division of Cell Biology, Metabolism & Cancer, Faculty of Veterinary Medicine, Utrecht University, 3584 CL Utrecht, The Netherlands.
Gröne A; Department of Biomolecular Health Sciences, Division of Pathology, Faculty of Veterinary Medicine, Utrecht University, 3584 CL Utrecht, The Netherlands.
Rijks JM; Dutch Wildlife Health Centre, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, 3584 CL Utrecht, The Netherlands.
de Vries RP; Department of Chemical Biology and Drug Discovery, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, 3584 CG Utrecht, The Netherlands.
Verheije MH; Department of Biomolecular Health Sciences, Division of Pathology, Faculty of Veterinary Medicine, Utrecht University, 3584 CL Utrecht, The Netherlands.
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Źródło:
Viruses [Viruses] 2021 Mar 31; Vol. 13 (4). Date of Electronic Publication: 2021 Mar 31.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Tissue Array Analysis*
Viral Tropism*
Virus Attachment*
Hemagglutinins, Viral/*metabolism
Respiratory System/*virology
Thogotovirus/*physiology
Viral Fusion Proteins/*metabolism
Animals ; Animals, Domestic/virology ; Cattle ; Goats ; Hemagglutinins, Viral/genetics ; Horses ; Host Microbial Interactions ; Recombinant Proteins/metabolism ; Sheep ; Sialic Acids/metabolism ; Swine ; Thogotovirus/chemistry ; Thogotovirus/genetics ; Viral Fusion Proteins/genetics
Czasopismo naukowe
Tytuł:
Development of a functional salivary gland tissue chip with potential for high-content drug screening.
Autorzy:
Song Y; Department of Biomedical Engineering, University of Rochester, Rochester, NY, USA.; Center for Oral Biology, University of Rochester Medical Center, Rochester, NY, USA.
Uchida H; Center for Oral Biology, University of Rochester Medical Center, Rochester, NY, USA.; Department of Biomedical Genetics, University of Rochester Medical Center, Rochester, NY, USA.
Sharipol A; Department of Biomedical Engineering, University of Rochester, Rochester, NY, USA.; Center for Oral Biology, University of Rochester Medical Center, Rochester, NY, USA.
Piraino L; Department of Biomedical Engineering, University of Rochester, Rochester, NY, USA.; Center for Oral Biology, University of Rochester Medical Center, Rochester, NY, USA.; Department of Dermatology, University of Rochester Medical Center, Rochester, NY, USA.
Mereness JA; Department of Biomedical Engineering, University of Rochester, Rochester, NY, USA.; Center for Oral Biology, University of Rochester Medical Center, Rochester, NY, USA.; Department of Environmental Medicine, University of Rochester Medical Center, Rochester, NY, USA.
Ingalls MH; Center for Oral Biology, University of Rochester Medical Center, Rochester, NY, USA.; Department of Biomedical Genetics, University of Rochester Medical Center, Rochester, NY, USA.
Rebhahn J; David H. Smith Center for Vaccine Biology and Immunology, University of Rochester Medical Center, Rochester, NY, USA.
Newlands SD; Department of Otolaryngology, University of Rochester Medical Center, Rochester, NY, USA.; Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA.; Department of Neuroscience, University of Rochester Medical Center, Rochester, NY, USA.
DeLouise LA; Department of Biomedical Engineering, University of Rochester, Rochester, NY, USA.; Center for Oral Biology, University of Rochester Medical Center, Rochester, NY, USA.; Department of Dermatology, University of Rochester Medical Center, Rochester, NY, USA.; Materials Science Program, University of Rochester, Rochester, NY, USA.
Ovitt CE; Center for Oral Biology, University of Rochester Medical Center, Rochester, NY, USA.; Department of Biomedical Genetics, University of Rochester Medical Center, Rochester, NY, USA.; Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA.
Benoit DSW; Department of Biomedical Engineering, University of Rochester, Rochester, NY, USA. .; Center for Oral Biology, University of Rochester Medical Center, Rochester, NY, USA. .; Department of Biomedical Genetics, University of Rochester Medical Center, Rochester, NY, USA. .; Department of Environmental Medicine, University of Rochester Medical Center, Rochester, NY, USA. .; Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA. .; Materials Science Program, University of Rochester, Rochester, NY, USA. .; Department of Chemical Engineering, University of Rochester, Rochester, NY, USA. .; Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, NY, USA. .
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Źródło:
Communications biology [Commun Biol] 2021 Mar 19; Vol. 4 (1), pp. 361. Date of Electronic Publication: 2021 Mar 19.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Video-Audio Media
MeSH Terms:
Drug Evaluation, Preclinical*
High-Throughput Screening Assays*
Tissue Array Analysis*
Acinar Cells/*drug effects
Radiation Injuries/*prevention & control
Salivary Glands/*drug effects
Xerostomia/*prevention & control
Acinar Cells/metabolism ; Acinar Cells/radiation effects ; Animals ; Calcium Signaling/drug effects ; Cells, Cultured ; Female ; Humans ; Hydrogels ; Male ; Mice, Inbred C57BL ; Microbubbles ; Middle Aged ; Parotid Gland/drug effects ; Parotid Gland/metabolism ; Parotid Gland/radiation effects ; Phenotype ; Polyethylene Glycols/chemistry ; Radiation Injuries/etiology ; Radiation Injuries/metabolism ; Salivary Glands/metabolism ; Salivary Glands/radiation effects ; Xerostomia/etiology ; Xerostomia/metabolism ; Mice
Czasopismo naukowe
Tytuł:
Classification of colorectal tissue images from high throughput tissue microarrays by ensemble deep learning methods.
Autorzy:
Nguyen HG; Institute of Pathology, University of Bern, Murtenstrasse 31, 3008, Bern, Switzerland.
Blank A; Institute of Pathology, University of Bern, Murtenstrasse 31, 3008, Bern, Switzerland.; Institute of Pathology, Triemli City Hospital, Birmensdorferstrasse 497, 8063, Zurich, Switzerland.
Dawson HE; Institute of Pathology, University of Bern, Murtenstrasse 31, 3008, Bern, Switzerland.
Lugli A; Institute of Pathology, University of Bern, Murtenstrasse 31, 3008, Bern, Switzerland.
Zlobec I; Institute of Pathology, University of Bern, Murtenstrasse 31, 3008, Bern, Switzerland. .
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Źródło:
Scientific reports [Sci Rep] 2021 Jan 27; Vol. 11 (1), pp. 2371. Date of Electronic Publication: 2021 Jan 27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Deep Learning*
Image Processing, Computer-Assisted*/methods
Immunohistochemistry*/methods
Tissue Array Analysis*/methods
Colorectal Neoplasms/*metabolism
Colorectal Neoplasms/*pathology
Algorithms ; Colorectal Neoplasms/etiology ; Computational Biology/methods ; Humans ; Reproducibility of Results
Czasopismo naukowe
Tytuł:
Deep learned tissue "fingerprints" classify breast cancers by ER/PR/Her2 status from H&E images.
Autorzy:
Rawat RR; Lawrence J. Ellison Institute for Transformative Medicine, University of Southern California, 12414 Exposition Blvd, Los Angeles, CA, 90064, USA.
Ortega I; Lawrence J. Ellison Institute for Transformative Medicine, University of Southern California, 12414 Exposition Blvd, Los Angeles, CA, 90064, USA.
Roy P; Lawrence J. Ellison Institute for Transformative Medicine, University of Southern California, 12414 Exposition Blvd, Los Angeles, CA, 90064, USA.
Sha F; DASH Center at USC, 1002 Childs Way, MCB 114, Los Angeles, CA, 90089-0005, USA.
Shibata D; Department of Pathology, University of Southern California Health Sciences Campus, NOR 1441 Eastlake Ave, Los Angeles, 90033, USA.
Ruderman D; Lawrence J. Ellison Institute for Transformative Medicine, University of Southern California, 12414 Exposition Blvd, Los Angeles, CA, 90064, USA. .
Agus DB; Lawrence J. Ellison Institute for Transformative Medicine, University of Southern California, 12414 Exposition Blvd, Los Angeles, CA, 90064, USA.
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Źródło:
Scientific reports [Sci Rep] 2020 Apr 29; Vol. 10 (1), pp. 7275. Date of Electronic Publication: 2020 Apr 29.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Breast Neoplasms*/diagnosis
Breast Neoplasms*/metabolism
Breast Neoplasms*/pathology
Deep Learning*
Image Processing, Computer-Assisted*
Tissue Array Analysis*
Biomarkers, Tumor/*metabolism
Progesterone/*metabolism
Receptor, ErbB-2/*metabolism
Receptors, Estrogen/*metabolism
Adult ; Aged ; Female ; Humans ; Middle Aged
Czasopismo naukowe
Tytuł:
The adequacy of tissue microarrays in the assessment of inter- and intra-tumoural heterogeneity of infiltrating lymphocyte burden in leiomyosarcoma.
Autorzy:
Lee ATJ; Sarcoma Unit, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK.; Division of Molecular Pathology, The Institute of Cancer Research, London, SW3 6JB, UK.
Chew W; Division of Molecular Pathology, The Institute of Cancer Research, London, SW3 6JB, UK.
Wilding CP; Division of Molecular Pathology, The Institute of Cancer Research, London, SW3 6JB, UK.
Guljar N; Division of Molecular Pathology, The Institute of Cancer Research, London, SW3 6JB, UK.
Smith MJ; Sarcoma Unit, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK.
Strauss DC; Sarcoma Unit, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK.
Fisher C; Sarcoma Unit, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK.
Hayes AJ; Sarcoma Unit, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK.
Judson I; Sarcoma Unit, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK.
Thway K; Sarcoma Unit, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK.
Jones RL; Sarcoma Unit, The Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK.; Division of Clinical Studies, The Institute of Cancer Research, London, SW3 6JB, UK.
Huang PH; Division of Molecular Pathology, The Institute of Cancer Research, London, SW3 6JB, UK. .
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Źródło:
Scientific reports [Sci Rep] 2019 Oct 10; Vol. 9 (1), pp. 14602. Date of Electronic Publication: 2019 Oct 10.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Tissue Array Analysis*
Leiomyosarcoma/*immunology
Lymphocytes, Tumor-Infiltrating/*cytology
Soft Tissue Neoplasms/*immunology
Adult ; Aged ; Aged, 80 and over ; Biomarkers, Tumor/analysis ; Female ; Humans ; Immunohistochemistry ; Male ; Middle Aged ; Reproducibility of Results ; Retrospective Studies ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
Medium throughput breathing human primary cell alveolus-on-chip model.
Autorzy:
Stucki JD; ARTORG Center for Biomedical Engineering Research, Organs-on-Chip Technologies, University of Bern, Bern, Switzerland.; AlveoliX AG, Bern, Switzerland.
Hobi N; ARTORG Center for Biomedical Engineering Research, Organs-on-Chip Technologies, University of Bern, Bern, Switzerland.; Institute of General Physiology, University of Ulm, Ulm, Germany.; AlveoliX AG, Bern, Switzerland.
Galimov A; ARTORG Center for Biomedical Engineering Research, Organs-on-Chip Technologies, University of Bern, Bern, Switzerland.
Stucki AO; ARTORG Center for Biomedical Engineering Research, Organs-on-Chip Technologies, University of Bern, Bern, Switzerland.
Schneider-Daum N; Helmholtz Institute for Pharmaceutical Research Saarland, Helmholtz Center for Infection Research, Biopharmaceutics and Pharmaceutical Technology, Saarland University, Saarbrücken, Germany.
Lehr CM; Helmholtz Institute for Pharmaceutical Research Saarland, Helmholtz Center for Infection Research, Biopharmaceutics and Pharmaceutical Technology, Saarland University, Saarbrücken, Germany.
Huwer H; SHG Clinics, Department of Cardiothoracic Surgery, Völklingen Heart Center, Völklingen, Germany.
Frick M; Institute of General Physiology, University of Ulm, Ulm, Germany.
Funke-Chambour M; Department of Pulmonary Medicine, University Hospital of Bern, Bern, Switzerland.; Department for Biomedical Research, University of Bern, Bern, Switzerland.
Geiser T; Department of Pulmonary Medicine, University Hospital of Bern, Bern, Switzerland.; Department for Biomedical Research, University of Bern, Bern, Switzerland.; AlveoliX AG, Bern, Switzerland.
Guenat OT; ARTORG Center for Biomedical Engineering Research, Organs-on-Chip Technologies, University of Bern, Bern, Switzerland. .; Department of Pulmonary Medicine, University Hospital of Bern, Bern, Switzerland. .; Division of General Thoracic Surgery, University Hospital of Bern, Bern, Switzerland. .; AlveoliX AG, Bern, Switzerland. .
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Źródło:
Scientific reports [Sci Rep] 2018 Sep 25; Vol. 8 (1), pp. 14359. Date of Electronic Publication: 2018 Sep 25.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Respiration*
Pulmonary Alveoli/*cytology
Tissue Array Analysis/*methods
Epithelial Cells/cytology ; Equipment Design ; Humans ; Pulmonary Alveoli/physiology ; Reproducibility of Results ; Tissue Array Analysis/instrumentation
Czasopismo naukowe
Tytuł:
Round robin study of formalin-fixed paraffin-embedded tissues in mass spectrometry imaging.
Autorzy:
Buck A; Research Unit Analytical Pathology, Helmholtz Zentrum München, 85764, Oberschleißheim, Germany.
Heijs B; Center for Proteomics and Metabolomics, Leiden University Medical Center, 2333 ZA, Leiden, The Netherlands.
Beine B; Medizinisches Proteom-Center, Ruhr-Universität Bochum, 44801, Bochum, Germany.; Leibniz-Institut für Analytische Wissenschaften - ISAS-e.V, 44139, Dortmund, Germany.
Schepers J; Department of Methodology and Statistics, Faculty of Psychology and Neuroscience, Maastricht University, 6200 MD, Maastricht, The Netherlands.
Cassese A; Department of Methodology and Statistics, Faculty of Psychology and Neuroscience, Maastricht University, 6200 MD, Maastricht, The Netherlands.
Heeren RMA; The Maastricht MultiModal Molecular Imaging Institute (M4I), Maastricht University, Universiteitssingel 50, Pigeon Hole 57, P.O. Box 616, 6200 MD, Maastricht, The Netherlands.
McDonnell LA; Center for Proteomics and Metabolomics, Leiden University Medical Center, 2333 ZA, Leiden, The Netherlands.; Fondazione Pisana per la Scienza ONLUS, 56017, Pisa, Italy.
Henkel C; Medizinisches Proteom-Center, Ruhr-Universität Bochum, 44801, Bochum, Germany.; Bruker Daltonik, Bremen, Germany.
Walch A; Research Unit Analytical Pathology, Helmholtz Zentrum München, 85764, Oberschleißheim, Germany.
Balluff B; The Maastricht MultiModal Molecular Imaging Institute (M4I), Maastricht University, Universiteitssingel 50, Pigeon Hole 57, P.O. Box 616, 6200 MD, Maastricht, The Netherlands. .
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Źródło:
Analytical and bioanalytical chemistry [Anal Bioanal Chem] 2018 Sep; Vol. 410 (23), pp. 5969-5980. Date of Electronic Publication: 2018 Jul 03.
Typ publikacji:
Journal Article
MeSH Terms:
Mass Spectrometry*/methods
Metabolomics*/methods
Paraffin Embedding*/methods
Tissue Array Analysis*/methods
Tissue Fixation*/methods
Peptides/*analysis
Animals ; Formaldehyde/chemistry ; Mice ; Proteomics/methods ; Reproducibility of Results
Czasopismo naukowe
Tytuł:
Tissue-based quantitative proteomics to screen and identify the potential biomarkers for early recurrence/metastasis of esophageal squamous cell carcinoma.
Autorzy:
Cai XW; Department of Radiation Oncology, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China.; Department of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai, China.
Yu WW; Department of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai, China.; Department of Radiation Oncology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
Yu W; Department of Radiation Oncology, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China.; Department of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai, China.
Zhang Q; Department of Radiation Oncology, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China.; Department of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai, China.
Feng W; Department of Radiation Oncology, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China.; Department of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai, China.
Liu MN; Department of Radiation Oncology, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China.; Department of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai, China.
Sun MH; Department of Pathology, Fudan University Shanghai Cancer Center, Shanghai, China.
Xiang JQ; Department of Thoracic Surgery, Fudan University Shanghai Cancer Center, Shanghai, China.
Zhang YW; Department of Thoracic Surgery, Fudan University Shanghai Cancer Center, Shanghai, China.
Fu XL; Department of Radiation Oncology, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China.; Department of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai, China.
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Źródło:
Cancer medicine [Cancer Med] 2018 Jun; Vol. 7 (6), pp. 2504-2517. Date of Electronic Publication: 2018 Apr 23.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Biomarkers, Tumor*
Proteomics*/methods
Tissue Array Analysis*/methods
Esophageal Squamous Cell Carcinoma/*metabolism
Esophageal Squamous Cell Carcinoma/*pathology
Cell Line, Tumor ; Esophageal Squamous Cell Carcinoma/genetics ; Esophageal Squamous Cell Carcinoma/mortality ; Gene Expression Profiling ; Humans ; Immunohistochemistry ; Neoplasm Metastasis ; Neoplasm Staging ; Prohibitins ; Recurrence
Czasopismo naukowe
Tytuł:
ADP-ribosylation factor 6 expression increase in oesophageal adenocarcinoma suggests a potential biomarker role for it.
Autorzy:
Kanamarlapudi V; Institute of Life Science 1, School of Medicine, Swansea University, Singleton Park, Swansea, United Kingdom.
Tamaddon-Jahromi S; Institute of Life Science 1, School of Medicine, Swansea University, Singleton Park, Swansea, United Kingdom.
Murphy K; Cellular Pathology, Swansea Bay University Health Board, Singleton Hospital, Swansea, United Kingdom.
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Źródło:
PloS one [PLoS One] 2022 Feb 10; Vol. 17 (2), pp. e0263845. Date of Electronic Publication: 2022 Feb 10 (Print Publication: 2022).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Up-Regulation*
ADP-Ribosylation Factor 6/*genetics
ADP-Ribosylation Factor 6/*metabolism
Adenocarcinoma/*pathology
Esophageal Neoplasms/*pathology
Adenocarcinoma/genetics ; Adenocarcinoma/metabolism ; Biomarkers, Tumor/genetics ; Biomarkers, Tumor/metabolism ; Case-Control Studies ; Disease Progression ; Esophageal Neoplasms/genetics ; Esophageal Neoplasms/metabolism ; Gene Expression Regulation, Neoplastic ; Humans ; Neoplasm Grading ; Tissue Array Analysis
SCR Disease Name:
Adenocarcinoma Of Esophagus
Czasopismo naukowe
Tytuł:
Novel rapid immunohistochemistry using an alternating current electric field identifies Rac and Cdc42 activation in human colon cancer FFPE tissues.
Autorzy:
Tsuda M; Department of Cancer Pathology, Faculty of Medicine, Hokkaido University, N15, W7, Kita-ku, Sapporo, 060-8638, Japan.; Institute for Chemical Reaction Design and Discovery (WPI-ICReDD), Hokkaido University, Sapporo, Japan.; Global Station for Soft Matter, Global Institution for Collaborative Research and Education, Hokkaido University, Sapporo, Japan.
Horio R; Department of Cancer Pathology, Faculty of Medicine, Hokkaido University, N15, W7, Kita-ku, Sapporo, 060-8638, Japan.
Wang L; Department of Cancer Pathology, Faculty of Medicine, Hokkaido University, N15, W7, Kita-ku, Sapporo, 060-8638, Japan.; Institute for Chemical Reaction Design and Discovery (WPI-ICReDD), Hokkaido University, Sapporo, Japan.; Global Station for Soft Matter, Global Institution for Collaborative Research and Education, Hokkaido University, Sapporo, Japan.
Takenami T; Department of Cancer Pathology, Faculty of Medicine, Hokkaido University, N15, W7, Kita-ku, Sapporo, 060-8638, Japan.
Moriya J; Department of Cancer Pathology, Faculty of Medicine, Hokkaido University, N15, W7, Kita-ku, Sapporo, 060-8638, Japan.
Suzuka J; Department of Cancer Pathology, Faculty of Medicine, Hokkaido University, N15, W7, Kita-ku, Sapporo, 060-8638, Japan.; Global Station for Soft Matter, Global Institution for Collaborative Research and Education, Hokkaido University, Sapporo, Japan.
Sugino H; Department of Cancer Pathology, Faculty of Medicine, Hokkaido University, N15, W7, Kita-ku, Sapporo, 060-8638, Japan.
Tanei Z; Department of Cancer Pathology, Faculty of Medicine, Hokkaido University, N15, W7, Kita-ku, Sapporo, 060-8638, Japan.
Tanino M; Department of Cancer Pathology, Faculty of Medicine, Hokkaido University, N15, W7, Kita-ku, Sapporo, 060-8638, Japan.; Department of Diagnostic Pathology, Asahikawa Medical University Hospital, Asahikawa, Japan.
Tanaka S; Department of Cancer Pathology, Faculty of Medicine, Hokkaido University, N15, W7, Kita-ku, Sapporo, 060-8638, Japan. .; Institute for Chemical Reaction Design and Discovery (WPI-ICReDD), Hokkaido University, Sapporo, Japan. .; Global Station for Soft Matter, Global Institution for Collaborative Research and Education, Hokkaido University, Sapporo, Japan. .
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Źródło:
Scientific reports [Sci Rep] 2022 Feb 02; Vol. 12 (1), pp. 1733. Date of Electronic Publication: 2022 Feb 02.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Immunohistochemistry*
Biomarkers, Tumor/*metabolism
Colonic Neoplasms/*enzymology
cdc42 GTP-Binding Protein/*metabolism
rac GTP-Binding Proteins/*metabolism
Animals ; Colonic Neoplasms/pathology ; Electricity ; Enzyme Activation ; HCT116 Cells ; HEK293 Cells ; Humans ; Mice, Inbred BALB C ; Mice, Nude ; Neoplasm Invasiveness ; Neoplasm Staging ; Predictive Value of Tests ; Tissue Array Analysis ; Mice
Czasopismo naukowe
Tytuł:
Comparison of RNAscope and immunohistochemistry for evaluation of the UPK2 status in urothelial carcinoma tissues.
Autorzy:
Lu J; Department of Pathology, Sun Yat-sen University Cancer Center, 510060, Guangzhou, P. R. China.; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University, 510060, Guangzhou, P. R. China.
Zhao M; Cancer Center, Department of Pathology, Zhejiang Provincial People's Hospital, Affiliated People's Hosipital Hangzhou Medical College, 310014, Hangzhou, Zhejiang, P. R. China.
Wu C; Department of Pathology, Sun Yat-sen University Cancer Center, 510060, Guangzhou, P. R. China.; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University, 510060, Guangzhou, P. R. China.
Chu C; Department of Pathology, Sun Yat-sen University Cancer Center, 510060, Guangzhou, P. R. China.; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University, 510060, Guangzhou, P. R. China.
Zhang CZ; Key Laboratory of Functional Protein Research of Guangdong Higher Education Institutes and MOE Key Laboratory of Tumor Molecular Biology, Institute of Life and Health Engineering, College of Life Science and Technology, Jinan University, 510632, Guangzhou, P.R. China. .
Cao Y; Department of Pathology, Sun Yat-sen University Cancer Center, 510060, Guangzhou, P. R. China. .; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University, 510060, Guangzhou, P. R. China. .
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Źródło:
Diagnostic pathology [Diagn Pathol] 2022 Jan 14; Vol. 17 (1), pp. 10. Date of Electronic Publication: 2022 Jan 14.
Typ publikacji:
Comparative Study; Journal Article
MeSH Terms:
Biomarkers, Tumor/*metabolism
Carcinoma, Transitional Cell/*diagnosis
Carcinoma, Transitional Cell/*metabolism
Urinary Bladder Neoplasms/*diagnosis
Urinary Bladder Neoplasms/*metabolism
Uroplakin II/*metabolism
Adult ; Aged ; Aged, 80 and over ; Female ; Humans ; Immunohistochemistry ; Male ; Middle Aged ; Sensitivity and Specificity ; Tissue Array Analysis
Czasopismo naukowe
Tytuł:
In Vitro and Clinical Evaluation of Cannabigerol (CBG) Produced via Yeast Biosynthesis: A Cannabinoid with a Broad Range of Anti-Inflammatory and Skin Health-Boosting Properties.
Autorzy:
Perez E; Research and Development Department, Signum Biosciences, 11 Deer Park Drive Suite 202, Monmouth Junction, NJ 08852, USA.
Fernandez JR; Research and Development Department, Signum Biosciences, 11 Deer Park Drive Suite 202, Monmouth Junction, NJ 08852, USA.
Fitzgerald C; Research and Development Department, Signum Biosciences, 11 Deer Park Drive Suite 202, Monmouth Junction, NJ 08852, USA.
Rouzard K; Research and Development Department, Signum Biosciences, 11 Deer Park Drive Suite 202, Monmouth Junction, NJ 08852, USA.
Tamura M; Research and Development Department, Signum Biosciences, 11 Deer Park Drive Suite 202, Monmouth Junction, NJ 08852, USA.
Savile C; Willow Biosciences, Inc., 1201-5th St. SW, Suite 202, Calgary, AB T2L 1Y8, Canada.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2022 Jan 13; Vol. 27 (2). Date of Electronic Publication: 2022 Jan 13.
Typ publikacji:
Journal Article
MeSH Terms:
Anti-Inflammatory Agents/*pharmacology
Cannabinoids/*biosynthesis
Cannabinoids/*pharmacology
Dermatologic Agents/*pharmacology
Saccharomyces cerevisiae/*genetics
Anti-Inflammatory Agents/therapeutic use ; Antioxidants/pharmacology ; Antioxidants/therapeutic use ; Cannabidiol/pharmacology ; Cannabinoids/therapeutic use ; Cells, Cultured ; Dermatitis, Contact/drug therapy ; Dermatitis, Contact/etiology ; Dermatologic Agents/therapeutic use ; Female ; Gene Expression Regulation/drug effects ; Healthy Volunteers ; Humans ; Inflammation/etiology ; Inflammation/prevention & control ; Male ; Models, Biological ; Propionibacteriaceae ; Skin/drug effects ; Skin Aging/drug effects ; Skin Irritancy Tests ; Sodium Dodecyl Sulfate/toxicity ; Tetradecanoylphorbol Acetate/adverse effects ; Tissue Array Analysis ; Ultraviolet Rays/adverse effects
SCR Organism:
Cutibacterium acnes subsp. acnes
Czasopismo naukowe
Tytuł:
RRM2 expression in different molecular subtypes of breast cancer and its prognostic significance.
Autorzy:
Abdel-Rahman MA; Department of Pathology, Faculty of Medicine, Mansoura University, El-Gomhoria St., Mansoura, Dakahlia, Egypt.
Mahfouz M; Department of Pathology, Faculty of Medicine, Mansoura University, El-Gomhoria St., Mansoura, Dakahlia, Egypt.
Habashy HO; Department of Pathology, Faculty of Medicine, Mansoura University, El-Gomhoria St., Mansoura, Dakahlia, Egypt. .
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Źródło:
Diagnostic pathology [Diagn Pathol] 2022 Jan 05; Vol. 17 (1), pp. 1. Date of Electronic Publication: 2022 Jan 05.
Typ publikacji:
Journal Article
MeSH Terms:
Biomarkers, Tumor/*metabolism
Breast Neoplasms/*diagnosis
Carcinoma/*diagnosis
Ribonucleoside Diphosphate Reductase/*metabolism
Adult ; Aged ; Aged, 80 and over ; Breast Neoplasms/metabolism ; Breast Neoplasms/mortality ; Carcinoma/metabolism ; Carcinoma/mortality ; Egypt ; Female ; Humans ; Immunohistochemistry ; Middle Aged ; Prognosis ; Retrospective Studies ; Survival Analysis ; Tissue Array Analysis
Czasopismo naukowe
Tytuł:
Feature Genes Selection Using Supervised Locally Linear Embedding and Correlation Coefficient for Microarray Classification.
Autorzy:
Xu J; College of Computer and Information Engineering, Henan Normal University, Xinxiang 453007, China.; Engineering Technology Research Center for Computing Intelligence and Data Mining, Henan Province 453007, China.
Mu H; College of Computer and Information Engineering, Henan Normal University, Xinxiang 453007, China.
Wang Y; College of Computer and Information Engineering, Henan Normal University, Xinxiang 453007, China.
Huang F; College of Computer and Information Engineering, Henan Normal University, Xinxiang 453007, China.
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Źródło:
Computational and mathematical methods in medicine [Comput Math Methods Med] 2018 Jan 31; Vol. 2018, pp. 5490513. Date of Electronic Publication: 2018 Jan 31 (Print Publication: 2018).
Typ publikacji:
Journal Article
MeSH Terms:
Computational Biology*
Gene Expression Profiling*
Linear Models*
Oligonucleotide Array Sequence Analysis*
Tissue Array Analysis*
Neoplasms/*genetics
Algorithms ; Bayes Theorem ; Data Interpretation, Statistical ; Databases, Genetic ; False Positive Reactions ; Humans ; Reproducibility of Results ; Software
Czasopismo naukowe
Tytuł:
Novel Criteria for Intratumoral Budding with Prognostic Relevance for Colon Cancer and Its Histological Subtypes.
Autorzy:
Pour Farid P; Experimental Tumorpathology, University Hospital, Friedrich-Alexander-University of Erlangen-Nüremberg (FAU), 91054 Erlangen, Germany.; Institute of Pathology, University Hospital, Friedrich-Alexander-University of Erlangen-Nüremberg (FAU), 91054 Erlangen, Germany.; Comprehensive Cancer Center-EMN (CCC), University Hospital, Friedrich-Alexander-University of Erlangen-Nüremberg (FAU), 91054 Erlangen, Germany.
Eckstein M; Institute of Pathology, University Hospital, Friedrich-Alexander-University of Erlangen-Nüremberg (FAU), 91054 Erlangen, Germany.; Comprehensive Cancer Center-EMN (CCC), University Hospital, Friedrich-Alexander-University of Erlangen-Nüremberg (FAU), 91054 Erlangen, Germany.
Merkel S; Comprehensive Cancer Center-EMN (CCC), University Hospital, Friedrich-Alexander-University of Erlangen-Nüremberg (FAU), 91054 Erlangen, Germany.; Department of Surgery, University Hospital, Friedrich-Alexander-University of Erlangen-Nüremberg (FAU), 91054 Erlangen, Germany.
Grützmann R; Comprehensive Cancer Center-EMN (CCC), University Hospital, Friedrich-Alexander-University of Erlangen-Nüremberg (FAU), 91054 Erlangen, Germany.; Department of Surgery, University Hospital, Friedrich-Alexander-University of Erlangen-Nüremberg (FAU), 91054 Erlangen, Germany.
Hartmann A; Institute of Pathology, University Hospital, Friedrich-Alexander-University of Erlangen-Nüremberg (FAU), 91054 Erlangen, Germany.; Comprehensive Cancer Center-EMN (CCC), University Hospital, Friedrich-Alexander-University of Erlangen-Nüremberg (FAU), 91054 Erlangen, Germany.
Bruns V; Fraunhofer Institute for Integrated Circuits IIS, Am Wolfsmantel 33, 91058 Erlangen, Germany.
Benz M; Fraunhofer Institute for Integrated Circuits IIS, Am Wolfsmantel 33, 91058 Erlangen, Germany.
Schneider-Stock R; Experimental Tumorpathology, University Hospital, Friedrich-Alexander-University of Erlangen-Nüremberg (FAU), 91054 Erlangen, Germany.; Institute of Pathology, University Hospital, Friedrich-Alexander-University of Erlangen-Nüremberg (FAU), 91054 Erlangen, Germany.; Comprehensive Cancer Center-EMN (CCC), University Hospital, Friedrich-Alexander-University of Erlangen-Nüremberg (FAU), 91054 Erlangen, Germany.
Geppert CI; Institute of Pathology, University Hospital, Friedrich-Alexander-University of Erlangen-Nüremberg (FAU), 91054 Erlangen, Germany.; Comprehensive Cancer Center-EMN (CCC), University Hospital, Friedrich-Alexander-University of Erlangen-Nüremberg (FAU), 91054 Erlangen, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Dec 03; Vol. 22 (23). Date of Electronic Publication: 2021 Dec 03.
Typ publikacji:
Journal Article
MeSH Terms:
Adenocarcinoma, Mucinous/*pathology
Carcinoma, Medullary/*pathology
Carcinoma, Signet Ring Cell/*pathology
Colonic Neoplasms/*pathology
Adenocarcinoma, Mucinous/metabolism ; Biomarkers, Tumor/metabolism ; Carcinoma, Medullary/metabolism ; Carcinoma, Signet Ring Cell/metabolism ; Colonic Neoplasms/metabolism ; Disease Progression ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; Male ; Neoplasm Metastasis ; Neoplasm Staging ; Prognosis ; Survival Analysis ; Tissue Array Analysis
Czasopismo naukowe
Tytuł:
xDEEP-MSI: Explainable Bias-Rejecting Microsatellite Instability Deep Learning System in Colorectal Cancer.
Autorzy:
Bustos A; AI Cancer Research Unit, MedBravo, 03560 Alicante, Spain.
Payá A; Pathology Department, Alicante University General Hospital (HGUA), 03010 Alicante, Spain.; Alicante Institute for Health and Biomedical Research (ISABIAL), 03010 Alicante, Spain.
Torrubia A; AI Cancer Research Unit, MedBravo, 03560 Alicante, Spain.
Jover R; Pathology Department, Alicante University General Hospital (HGUA), 03010 Alicante, Spain.; Alicante Institute for Health and Biomedical Research (ISABIAL), 03010 Alicante, Spain.
Llor X; Department of Medicine, Yale Cancer Center, Yale University, New Haven, CT 06511, USA.
Bessa X; Gastroenterology Department, Hospital del Mar Medical Research Institute (IMIM), 08003 Barcelona, Spain.
Castells A; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Gastroenterology Department, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Hospital Clinic, University of Barcelona, 08036 Barcelona, Spain.
Carracedo Á; Fundación Pública Gallega de Medicina Genómica (GMX), 15706 Santiago de Compostela, Spain.
Alenda C; Pathology Department, Alicante University General Hospital (HGUA), 03010 Alicante, Spain.; Alicante Institute for Health and Biomedical Research (ISABIAL), 03010 Alicante, Spain.
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Źródło:
Biomolecules [Biomolecules] 2021 Nov 29; Vol. 11 (12). Date of Electronic Publication: 2021 Nov 29.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Microsatellite Instability*
Colorectal Neoplasms/*genetics
Computational Biology/*methods
Adult ; Aged ; Aged, 80 and over ; Algorithms ; Bias ; Biomarkers, Tumor/genetics ; Deep Learning ; Female ; Humans ; Male ; Middle Aged ; Tissue Array Analysis
Czasopismo naukowe
Tytuł:
Utilizing digital pathology to quantify stromal caveolin-1 expression in malignant and benign ovarian tumors: Associations with clinicopathological parameters and clinical outcomes.
Autorzy:
Saeed-Vafa D; Department of Anatomic Pathology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.
Marchion DC; Tissue Core-Biospecimen Processing Laboratory, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.
McCarthy SM; Department of Anatomic Pathology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.
Hakam A; Department of Anatomic Pathology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.
Lopez A; Department of Anatomic Pathology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.
Wenham RM; Department of Gynecologic Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.
Apte SM; Department of Gynecologic Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.
Chen DT; Department of Biostatistics and Bioinformatics, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.
Magliocco AM; Department of Anatomic Pathology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.
Lancaster JM; Department of Gynecologic Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.
Reid BM; Department of Cancer Epidemiology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.
Permuth JB; Department of Cancer Epidemiology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.
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Źródło:
PloS one [PLoS One] 2021 Nov 23; Vol. 16 (11), pp. e0256615. Date of Electronic Publication: 2021 Nov 23 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Caveolin 1/*metabolism
Cystadenocarcinoma, Serous/*metabolism
Ovarian Neoplasms/*metabolism
Ovary/*metabolism
Stromal Cells/*metabolism
Adult ; Aged ; Aged, 80 and over ; Biomarkers, Tumor/metabolism ; Cystadenocarcinoma, Serous/mortality ; Cystadenocarcinoma, Serous/pathology ; Down-Regulation ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; Immunohistochemistry ; Middle Aged ; Neoplasm Staging ; Ovarian Neoplasms/mortality ; Ovarian Neoplasms/pathology ; Ovary/pathology ; Stromal Cells/pathology ; Survival Rate ; Tissue Array Analysis
Czasopismo naukowe

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