Temat: "Tissue Distribution" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Monolacunary Wells-Dawson Polyoxometalate as a Novel Contrast Agent for Computed Tomography: A Comprehensive Study on In Vivo Toxicity and Biodistribution.
Autorzy:: Stojanović M; Department of Pharmacology, Clinical Pharmacology and Toxicology, Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.
Čolović MB; 'Vinča' Institute of Nuclear Sciences-National Institute of the Republic of Serbia, University of Belgrade, 11351 Belgrade, Serbia.
Lalatović J; Department of Radiology, University Hospital Medical Center Bežanijska Kosa, 11080 Belgrade, Serbia.
Milosavljević A; Institute of Histology and Embryology, Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.
Savić ND; Department of Chemistry, KU Leuven, Celestijnenlaan 200F, 3001 Leuven, Belgium.
Declerck K; Department of Chemistry, KU Leuven, Celestijnenlaan 200F, 3001 Leuven, Belgium.
Radosavljević B; Institute of Medical Chemistry, Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.
Ćetković M; Institute of Histology and Embryology, Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.
Kravić-Stevović T; Institute of Histology and Embryology, Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.
Parac-Vogt TN; Department of Chemistry, KU Leuven, Celestijnenlaan 200F, 3001 Leuven, Belgium.
Krstić D; Institute of Medical Chemistry, Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Feb 22; Vol. 25 (5). Date of Electronic Publication: 2024 Feb 22.
Typ publikacji:: Journal Article
MeSH Terms:: Contrast Media*
Iohexol*
Polyelectrolytes*
Anions*
Rats ; Animals ; Tissue Distribution ; Tungsten ; Tomography, X-Ray Computed

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Skocz do pozycji: 2.

Tytuł:: UHPLC-MS/MS Assay for Quantification of Legubicin, a Novel Doxorubicin-Based Legumain-Activated Prodrug, and Its Application to Pharmacokinetic and Tissue Distribution Studies.
Autorzy:: Ma L; Department of Pharmacology, School of Pharmacy, Fudan University, Shanghai 201203, China.; Shanghai Innostar Bio-Tech Co., Ltd., China State Institute of Pharmaceutical Industry, Shanghai 201203, China.
Yu Q; Shanghai Innostar Bio-Tech Co., Ltd., China State Institute of Pharmaceutical Industry, Shanghai 201203, China.
Zhuang M; Shanghai Innostar Bio-Tech Co., Ltd., China State Institute of Pharmaceutical Industry, Shanghai 201203, China.
Yang C; Shanghai Innostar Bio-Tech Co., Ltd., China State Institute of Pharmaceutical Industry, Shanghai 201203, China.
Liu Y; Shanghai Affinity Bio-Pharmaceuticals Co., Ltd., Shanghai 201203, China.
Li Y; Shanghai Affinity Bio-Pharmaceuticals Co., Ltd., Shanghai 201203, China.
Liu C; Shanghai Affinity Bio-Pharmaceuticals Co., Ltd., Shanghai 201203, China.
Shen X; Department of Pharmacology, School of Pharmacy, Fudan University, Shanghai 201203, China.
Chang Y; Shanghai Innostar Bio-Tech Co., Ltd., China State Institute of Pharmaceutical Industry, Shanghai 201203, China.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2024 Feb 08; Vol. 29 (4). Date of Electronic Publication: 2024 Feb 08.
Typ publikacji:: Journal Article
MeSH Terms:: Prodrugs*/chemistry
Neoplasms*
Cysteine Endopeptidases*
Mice ; Rats ; Animals ; Chromatography, High Pressure Liquid ; Tissue Distribution ; Tandem Mass Spectrometry ; Doxorubicin/chemistry ; Albumins

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Skocz do pozycji: 3.

Tytuł:: Peak transgene expression after intramuscular immunization of mice with adenovirus 26-based vector vaccines correlates with transgene-specific adaptive immune responses.
Autorzy:: Marquez-Martinez S; Janssen Vaccines & Prevention B.V, Leiden, CN, The Netherlands.
Salisch N; Janssen Vaccines & Prevention B.V, Leiden, CN, The Netherlands.
Serroyen J; Janssen Vaccines & Prevention B.V, Leiden, CN, The Netherlands.
Zahn R; Janssen Vaccines & Prevention B.V, Leiden, CN, The Netherlands.
Khan S; Janssen Vaccines & Prevention B.V, Leiden, CN, The Netherlands.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2024 Apr 16; Vol. 19 (4), pp. e0299215. Date of Electronic Publication: 2024 Apr 16 (Print Publication: 2024).
Typ publikacji:: Journal Article
MeSH Terms:: Adenovirus Vaccines*
Vaccines*
Spike Glycoprotein, Coronavirus*
Animals ; Mice ; Humans ; Immunity, Humoral ; Tissue Distribution ; Immunization ; Vaccination ; Adenoviridae/genetics ; Transgenes ; Genetic Vectors/genetics ; Antibodies, Viral

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Skocz do pozycji: 4.

Tytuł:: Mitochondrial DNA as a target for analyzing the biodistribution of cell therapy products.
Autorzy:: Cho YW; College of Pharmacy, Chungbuk National University, Cheongju, 28644, Republic of Korea.; Division of Drug Screening Evaluation, NDDC, Osong Medical Innovation Foundation, Cheongju, 28160, Republic of Korea.
Yoon J; Division of Drug Screening Evaluation, NDDC, Osong Medical Innovation Foundation, Cheongju, 28160, Republic of Korea.
Song SG; College of Pharmacy, Chungbuk National University, Cheongju, 28644, Republic of Korea. .
Noh YW; Division of Drug Screening Evaluation, NDDC, Osong Medical Innovation Foundation, Cheongju, 28160, Republic of Korea. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Apr 04; Vol. 14 (1), pp. 7934. Date of Electronic Publication: 2024 Apr 04.
Typ publikacji:: Journal Article
MeSH Terms:: DNA, Mitochondrial*/genetics
Mitochondria*/genetics
Humans ; Mice ; Animals ; Tissue Distribution ; DNA Primers

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Skocz do pozycji: 5.

Tytuł:: Efficacy and safety of mesenchymal stem cell therapy for ovarian ageing in a mouse model.
Autorzy:: Pei W; Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproductive Technology and Key Laboratory of Assisted Reproduction, Ministry of Education, Peking University Third Hospital, Beijing, 100191, China.; Clinical Stem Cell Research Center, Peking University Third Hospital, Beijing, 100191, China.; State Key Laboratory of Female Fertility Promotion, Peking University Third Hospital, Beijing, 100191, China.
Fu L; Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproductive Technology and Key Laboratory of Assisted Reproduction, Ministry of Education, Peking University Third Hospital, Beijing, 100191, China.; Clinical Stem Cell Research Center, Peking University Third Hospital, Beijing, 100191, China.; State Key Laboratory of Female Fertility Promotion, Peking University Third Hospital, Beijing, 100191, China.
Guo W; Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproductive Technology and Key Laboratory of Assisted Reproduction, Ministry of Education, Peking University Third Hospital, Beijing, 100191, China.; Clinical Stem Cell Research Center, Peking University Third Hospital, Beijing, 100191, China.; State Key Laboratory of Female Fertility Promotion, Peking University Third Hospital, Beijing, 100191, China.
Wang Y; Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproductive Technology and Key Laboratory of Assisted Reproduction, Ministry of Education, Peking University Third Hospital, Beijing, 100191, China.; Key Laboratory for Major Obstetric Diseases of Guangdong Province, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510150, China.
Fan Y; Key Laboratory for Major Obstetric Diseases of Guangdong Province, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510150, China.
Yang R; Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproductive Technology and Key Laboratory of Assisted Reproduction, Ministry of Education, Peking University Third Hospital, Beijing, 100191, China.; State Key Laboratory of Female Fertility Promotion, Peking University Third Hospital, Beijing, 100191, China.
Li R; Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproductive Technology and Key Laboratory of Assisted Reproduction, Ministry of Education, Peking University Third Hospital, Beijing, 100191, China.; State Key Laboratory of Female Fertility Promotion, Peking University Third Hospital, Beijing, 100191, China.
Qiao J; Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproductive Technology and Key Laboratory of Assisted Reproduction, Ministry of Education, Peking University Third Hospital, Beijing, 100191, China. .; State Key Laboratory of Female Fertility Promotion, Peking University Third Hospital, Beijing, 100191, China. .
Yu Y; Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproductive Technology and Key Laboratory of Assisted Reproduction, Ministry of Education, Peking University Third Hospital, Beijing, 100191, China. .; Clinical Stem Cell Research Center, Peking University Third Hospital, Beijing, 100191, China. .; State Key Laboratory of Female Fertility Promotion, Peking University Third Hospital, Beijing, 100191, China. .; Pokaż więcej
Źródło:: Stem cell research & therapy [Stem Cell Res Ther] 2024 Apr 03; Vol. 15 (1), pp. 96. Date of Electronic Publication: 2024 Apr 03.
Typ publikacji:: Journal Article
MeSH Terms:: Mesenchymal Stem Cell Transplantation*
Mesenchymal Stem Cells*/metabolism
Mice ; Animals ; Female ; Ovary/metabolism ; Tissue Distribution ; Cell Proliferation ; Disease Models, Animal ; Umbilical Cord

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Skocz do pozycji: 6.

Tytuł:: Intranasal delivery of phenytoin loaded layered double hydroxide nanoparticles improves therapeutic effect on epileptic seizures.
Autorzy:: Zhang J; Department of Neurology, The Fourth Affiliated Hospital, Zhejiang University School of Medicine, Yiwu, 322000, China.
Zuo H; The Fourth Affiliated Hospital, Zhejiang University School of Medicine, Yiwu, 322000, China.
Fu Y; Department of Neurology, The Fourth Affiliated Hospital, Zhejiang University School of Medicine, Yiwu, 322000, China.
Cao Y; Department of Neurology, The Fourth Affiliated Hospital, Zhejiang University School of Medicine, Yiwu, 322000, China.
Li Q; Department of Neurology, The Fourth Affiliated Hospital, Zhejiang University School of Medicine, Yiwu, 322000, China.
Zhang Q; Key Laboratory of Neuropharmacology and Translational Medicine of Zhejiang Province, School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, 310053, China.
Zheng Y; Key Laboratory of Neuropharmacology and Translational Medicine of Zhejiang Province, School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, 310053, China.
Wang Y; Key Laboratory of Neuropharmacology and Translational Medicine of Zhejiang Province, School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, 310053, China.
Wu D; Key Laboratory of Neuropharmacology and Translational Medicine of Zhejiang Province, School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, 310053, China.
Chen W; Department of Respiratory and Critical Care Medicine, The Fourth Affiliated Hospital, Zhejiang University School of Medicine, Yiwu, 322000, China. .
Fang J; Department of Neurology, The Fourth Affiliated Hospital, Zhejiang University School of Medicine, Yiwu, 322000, China. .; Pokaż więcej
Źródło:: Journal of nanobiotechnology [J Nanobiotechnology] 2024 Apr 02; Vol. 22 (1), pp. 144. Date of Electronic Publication: 2024 Apr 02.
Typ publikacji:: Journal Article
MeSH Terms:: Epilepsy*/drug therapy
Nanoparticles*/therapeutic use
Mice ; Animals ; Phenytoin/pharmacology ; Phenytoin/therapeutic use ; Administration, Intranasal ; Tissue Distribution ; Seizures/drug therapy ; Hydroxides/therapeutic use

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Skocz do pozycji: 7.

Tytuł:: Standard Radio-Iodine Labeling Protocols Impaired the Functional Integrity of Mesenchymal Stem/Stromal Cell Exosomes.
Autorzy:: Yang CT; Department of Nuclear Medicine and Molecular Imaging, Radiological Sciences Division, Singapore General Hospital, Outram Road, Singapore 169608, Singapore.; Duke-NUS Medical School, 8 College Road, Singapore 169857, Singapore.
Lai RC; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), 61 Biopolis Drive, Proteos, Singapore 138673, Singapore.; Paracrine Therapeutics Pte. Ltd., 10 Choa Chu Kang Grove #13-22 Sol Acres, Singapore 688207, Singapore.
Phua VJX; Department of Nuclear Medicine and Molecular Imaging, Radiological Sciences Division, Singapore General Hospital, Outram Road, Singapore 169608, Singapore.
Aw SE; Department of Nuclear Medicine and Molecular Imaging, Radiological Sciences Division, Singapore General Hospital, Outram Road, Singapore 169608, Singapore.; Duke-NUS Medical School, 8 College Road, Singapore 169857, Singapore.
Zhang B; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), 61 Biopolis Drive, Proteos, Singapore 138673, Singapore.; Paracrine Therapeutics Pte. Ltd., 10 Choa Chu Kang Grove #13-22 Sol Acres, Singapore 688207, Singapore.
Sim WK; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), 61 Biopolis Drive, Proteos, Singapore 138673, Singapore.; Paracrine Therapeutics Pte. Ltd., 10 Choa Chu Kang Grove #13-22 Sol Acres, Singapore 688207, Singapore.
Lim SK; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), 61 Biopolis Drive, Proteos, Singapore 138673, Singapore.; Paracrine Therapeutics Pte. Ltd., 10 Choa Chu Kang Grove #13-22 Sol Acres, Singapore 688207, Singapore.
Ng DCE; Department of Nuclear Medicine and Molecular Imaging, Radiological Sciences Division, Singapore General Hospital, Outram Road, Singapore 169608, Singapore.; Duke-NUS Medical School, 8 College Road, Singapore 169857, Singapore.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Mar 27; Vol. 25 (7). Date of Electronic Publication: 2024 Mar 27.
Typ publikacji:: Journal Article
MeSH Terms:: Exosomes*
Thyroid Neoplasms*
Mesenchymal Stem Cells*
Animals ; Iodine Radioisotopes ; Tissue Distribution

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Skocz do pozycji: 8.

Tytuł:: Development of a Mouse Experimental System for the In Vivo Characterization of Bioengineered Adipose-Derived Stromal Cells.
Autorzy:: Ichise T; Department of Plastic and Reconstructive Surgery, University of the Ryukyus Hospital, 207 Uehara, Nishihara 903-0215, Japan.
Ichise H; Institute for Animal Research, Faculty of Medicine, University of the Ryukyus, 207 Uehara, Nishihara 903-0215, Japan.
Shimizu Y; Department of Plastic and Reconstructive Surgery, University of the Ryukyus Hospital, 207 Uehara, Nishihara 903-0215, Japan.; Department of Plastic and Reconstructive Surgery, Graduate School of Medicine, University of the Ryukyus, 207 Uehara, Nishihara 903-0215, Japan.; Pokaż więcej
Źródło:: Cells [Cells] 2024 Mar 27; Vol. 13 (7). Date of Electronic Publication: 2024 Mar 27.
Typ publikacji:: Journal Article
MeSH Terms:: Adipose Tissue*
Endothelial Cells*
Humans ; Mice ; Animals ; Tissue Distribution ; Adipocytes ; Stromal Cells

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Skocz do pozycji: 9.

Tytuł:: The remodeling of ovarian function: targeted delivery strategies for mesenchymal stem cells and their derived extracellular vesicles.
Autorzy:: Song Y; Department of Gynecological Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, Hubei, China.; National Clinical Research Center for Obstetrics and Gynecology, Cancer Biology Research Center (Key Laboratory of the Ministry of Education), Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, Hubei, China.; Reproductive Medicine Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, Hubei, China.
Wu J; Department of Gynecological Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, Hubei, China.; National Clinical Research Center for Obstetrics and Gynecology, Cancer Biology Research Center (Key Laboratory of the Ministry of Education), Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, Hubei, China.
Liu Y; Department of Gynecological Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, Hubei, China.; National Clinical Research Center for Obstetrics and Gynecology, Cancer Biology Research Center (Key Laboratory of the Ministry of Education), Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, Hubei, China.
Xu N; Department of Gynecological Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, Hubei, China.; National Clinical Research Center for Obstetrics and Gynecology, Cancer Biology Research Center (Key Laboratory of the Ministry of Education), Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, Hubei, China.; Reproductive Medicine Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, Hubei, China.
Bai H; Department of Gynecological Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, Hubei, China.; National Clinical Research Center for Obstetrics and Gynecology, Cancer Biology Research Center (Key Laboratory of the Ministry of Education), Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, Hubei, China.
Wang L; National Clinical Research Center for Obstetrics and Gynecology, Cancer Biology Research Center (Key Laboratory of the Ministry of Education), Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, Hubei, China. .; Reproductive Medicine Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, Hubei, China. .
Ai J; Reproductive Medicine Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, Hubei, China. .
Li K; Department of Gynecological Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, Hubei, China. .; National Clinical Research Center for Obstetrics and Gynecology, Cancer Biology Research Center (Key Laboratory of the Ministry of Education), Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, Hubei, China. .; Pokaż więcej
Źródło:: Stem cell research & therapy [Stem Cell Res Ther] 2024 Mar 27; Vol. 15 (1), pp. 90. Date of Electronic Publication: 2024 Mar 27.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Extracellular Vesicles*/metabolism
Primary Ovarian Insufficiency*/therapy
Primary Ovarian Insufficiency*/metabolism
Mesenchymal Stem Cells*
Mesenchymal Stem Cell Transplantation*
Humans ; Female ; Quality of Life ; Tissue Distribution

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Skocz do pozycji: 10.

Tytuł:: Reductive prodrug and AIE copolymer nanoparticle for monitoring and chemotherapy.
Autorzy:: Wang Z; Department of Clinical Diagnosis, Laboratory of Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; NMPA Key Laboratory for Quality Control of In Vitro Diagnostics, Beijing, China.; Beijing Engineering Research Center of Immunological Reagents Clinical Research, Beijing, China.; Zhengzhou Immunobiotech Co, Ltd, Zhengzhou, 450016, P.R. China.
Li G; Zhengzhou Immunobiotech Co, Ltd, Zhengzhou, 450016, P.R. China.
Zhao Q; Zhengzhou Immunobiotech Co, Ltd, Zhengzhou, 450016, P.R. China.
Fu G; Autobio Diagnostics Co, LtdHenan, 450016, China.
Yang Z; Autobio Diagnostics Co, LtdHenan, 450016, China.
Zhang G; Department of Clinical Diagnosis, Laboratory of Beijing Tiantan Hospital, Capital Medical University, Beijing, China. .; NMPA Key Laboratory for Quality Control of In Vitro Diagnostics, Beijing, China. .; Beijing Engineering Research Center of Immunological Reagents Clinical Research, Beijing, China. .; Pokaż więcej
Źródło:: BMC cancer [BMC Cancer] 2024 Mar 26; Vol. 24 (1), pp. 382. Date of Electronic Publication: 2024 Mar 26.
Typ publikacji:: Journal Article
MeSH Terms:: Prodrugs*/pharmacology
Nanoparticles*/chemistry
Humans ; Micelles ; Tissue Distribution ; Drug Delivery Systems ; Polymers/chemistry

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Skocz do pozycji: 11.

Tytuł:: The Translation of Nanomedicines in the Contexts of Spinal Cord Injury and Repair.
Autorzy:: Wang W; School of Chemical Engineering, University of New South Wales (UNSW), Kensington, NSW 2052, Australia.
Yong J; School of Chemical Engineering, University of New South Wales (UNSW), Kensington, NSW 2052, Australia.
Marciano P; Adelaide Medical School, University of Adelaide, Adelaide, SA 5005, Australia.; Neil Sachse Centre for Spinal Cord Research, Lifelong Health Theme, South Australian Health and Medical Research Institute, North Terrace, Adelaide, SA 5000, Australia.
O'Hare Doig R; Adelaide Medical School, University of Adelaide, Adelaide, SA 5005, Australia.; Neil Sachse Centre for Spinal Cord Research, Lifelong Health Theme, South Australian Health and Medical Research Institute, North Terrace, Adelaide, SA 5000, Australia.
Mao G; School of Chemical Engineering, University of New South Wales (UNSW), Kensington, NSW 2052, Australia.
Clark J; Adelaide Medical School, University of Adelaide, Adelaide, SA 5005, Australia.; Neil Sachse Centre for Spinal Cord Research, Lifelong Health Theme, South Australian Health and Medical Research Institute, North Terrace, Adelaide, SA 5000, Australia.; Pokaż więcej
Źródło:: Cells [Cells] 2024 Mar 24; Vol. 13 (7). Date of Electronic Publication: 2024 Mar 24.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Nanomedicine*
Spinal Cord Injuries*/drug therapy
Spinal Cord Injuries*/pathology
Humans ; Tissue Distribution ; Regenerative Medicine

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Skocz do pozycji: 12.

Tytuł:: Influence of Molecular Design on the Tumor Targeting and Biodistribution of PSMA-Binding Tracers Labeled with Technetium-99m.
Autorzy:: Bezverkhniaia E; Department of Medicinal Chemistry, Uppsala University, 751 23 Uppsala, Sweden.
Kanellopoulos P; Department of Medicinal Chemistry, Uppsala University, 751 23 Uppsala, Sweden.
Rosenström U; Department of Medicinal Chemistry, Uppsala University, 751 23 Uppsala, Sweden.
Tolmachev V; Department of Immunology, Genetics and Pathology, Uppsala University, 752 37 Uppsala, Sweden.
Orlova A; Department of Medicinal Chemistry, Uppsala University, 751 23 Uppsala, Sweden.; Science for Life Laboratory, Uppsala University, 752 37 Uppsala, Sweden.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Mar 23; Vol. 25 (7). Date of Electronic Publication: 2024 Mar 23.
Typ publikacji:: Journal Article
MeSH Terms:: Technetium*
Fabaceae*
Animals ; Mice ; Tissue Distribution ; Ligands ; Chelating Agents ; Glutamic Acid ; Glycine

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Skocz do pozycji: 13.

Tytuł:: Asiatic acid cyclodextrin inclusion micro-cocrystal for insoluble drug delivery and acute lung injury therapy enhancement.
Autorzy:: Shen H; Zhongshan Institute for Drug Discovery, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Zhongshan, 528400, China.; State Key Laboratory of Drug Research, Chinese Academy of Sciences, Shanghai, 201203, China.
Pan L; School of Pharmacy, Zunyi Medical University, Zunyi, 563003, China.
Ning K; School of Pharmacy, Zunyi Medical University, Zunyi, 563003, China.
Fang Y; Zhongshan Institute for Drug Discovery, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Zhongshan, 528400, China.
Muhitdinov B; Institute of Bioorganic Chemistry, Uzbekistan Academy of Sciences, 83 M. Ulughbek Street, Tashkent, 100125, Uzbekistan.
Liu E; Zhongshan Institute for Drug Discovery, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Zhongshan, 528400, China. .
Huang Y; Zhongshan Institute for Drug Discovery, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Zhongshan, 528400, China. .; State Key Laboratory of Drug Research, Chinese Academy of Sciences, Shanghai, 201203, China. .; School of Pharmacy, Zunyi Medical University, Zunyi, 563003, China. .; NMPA Key Laboratory for Quality Research and Evaluation of Pharmaceutical Excipients, Shanghai, 201203, China. .; Pokaż więcej
Źródło:: Journal of nanobiotechnology [J Nanobiotechnology] 2024 Mar 17; Vol. 22 (1), pp. 119. Date of Electronic Publication: 2024 Mar 17.
Typ publikacji:: Journal Article
MeSH Terms:: Cyclodextrins*/chemistry
Acute Lung Injury*/drug therapy
Pentacyclic Triterpenes*
Humans ; Tissue Distribution ; Drug Delivery Systems ; Solubility

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Skocz do pozycji: 14.

Tytuł:: Natural Adeno-Associated Virus Serotypes and Engineered Adeno-Associated Virus Capsid Variants: Tropism Differences and Mechanistic Insights.
Autorzy:: Lopez-Gordo E; Affinia Therapeutics, Waltham, MA 02453, USA.
Chamberlain K; Independent Researcher, Bedford, MA 01730, USA.
Riyad JM; Independent Researcher, South Plainfield, NJ 07080, USA.
Kohlbrenner E; Spark Therapeutics, Philadelphia, PA 19104, USA.
Weber T; Spark Therapeutics, Philadelphia, PA 19104, USA.; Pokaż więcej
Źródło:: Viruses [Viruses] 2024 Mar 12; Vol. 16 (3). Date of Electronic Publication: 2024 Mar 12.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Capsid*/metabolism
Dependovirus*/metabolism
Serogroup ; Tissue Distribution ; Capsid Proteins/genetics ; Capsid Proteins/metabolism ; Tropism ; Genetic Vectors/genetics

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Skocz do pozycji: 15.

Tytuł:: Investigating the therapeutic effects and mechanisms of Carthamus tinctorius L.-derived nanovesicles in atherosclerosis treatment.
Autorzy:: Yang R; Department of Cardiology, The Eighth Affiliated Hospital, Sun Yat-sen University, Shenzhen, China.; NHC Key Laboratory of Assisted Circulation (Sun Yat-sen University), Shenzhen, China.
Lin F; Department of Cardiology, Shenzhen Bao'an Chinese Medicine Hospital, Guangzhou University of Chinese Medicine, Shenzhen, China.
Wang W; Department of Cardiology, Fuwai Hospital, Chinese Academy of Medical Sciences (Shenzhen Sun Yat-sen Cardiovascular Hospital), Shenzhen, China.; Department of Clinical Medicine, University of South China, Hengyang, China.
Dai G; NHC Key Laboratory of Assisted Circulation (Sun Yat-sen University), Shenzhen, China.
Ke X; Department of Cardiology, Fuwai Hospital, Chinese Academy of Medical Sciences (Shenzhen Sun Yat-sen Cardiovascular Hospital), Shenzhen, China. .
Wu G; Department of Cardiology, The Eighth Affiliated Hospital, Sun Yat-sen University, Shenzhen, China. .; Guangdong Innovative Engineering and Technology Research Center for Assisted Circulation, Shenzhen, China. .; NHC Key Laboratory of Assisted Circulation (Sun Yat-sen University), Shenzhen, China. .; Pokaż więcej
Źródło:: Cell communication and signaling : CCS [Cell Commun Signal] 2024 Mar 12; Vol. 22 (1), pp. 178. Date of Electronic Publication: 2024 Mar 12.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Carthamus tinctorius*/genetics
Carthamus tinctorius*/metabolism
Cardiovascular Diseases*/metabolism
MicroRNAs*/genetics
Atherosclerosis*/metabolism
Mice ; Animals ; Endothelial Cells/metabolism ; Tissue Distribution ; Mice, Knockout, ApoE ; Inflammation/metabolism ; Apoptosis ; RNA, Messenger/metabolism ; Apolipoproteins E/metabolism

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Skocz do pozycji: 16.

Tytuł:: A proof-of-concept study on bioorthogonal-based pretargeting and signal amplify radiotheranostic strategy.
Autorzy:: Yang H; State Key Laboratory of Vaccines for Infectious Diseases, Center for Molecular Imaging and Translational Medicine, Xiang An Biomedicine Laboratory, School of Public Health, Xiamen University, Xiamen, 361102, China.
Zeng X; State Key Laboratory of Vaccines for Infectious Diseases, Center for Molecular Imaging and Translational Medicine, Xiang An Biomedicine Laboratory, School of Public Health, Xiamen University, Xiamen, 361102, China.
Liu J; State Key Laboratory of Vaccines for Infectious Diseases, Center for Molecular Imaging and Translational Medicine, Xiang An Biomedicine Laboratory, School of Public Health, Xiamen University, Xiamen, 361102, China.
Li J; PET Center, Department of Nuclear Medicine, School of Medicine, The First Affiliated Hospital, Zhejiang University, 79 Qingchun Road, Hangzhou, 310003, China.
Li Y; State Key Laboratory of Vaccines for Infectious Diseases, Center for Molecular Imaging and Translational Medicine, Xiang An Biomedicine Laboratory, School of Public Health, Xiamen University, Xiamen, 361102, China.
Zhang Q; State Key Laboratory of Vaccines for Infectious Diseases, Center for Molecular Imaging and Translational Medicine, Xiang An Biomedicine Laboratory, School of Public Health, Xiamen University, Xiamen, 361102, China.
Shu L; State Key Laboratory of Vaccines for Infectious Diseases, Center for Molecular Imaging and Translational Medicine, Xiang An Biomedicine Laboratory, School of Public Health, Xiamen University, Xiamen, 361102, China.
Liu H; State Key Laboratory of Vaccines for Infectious Diseases, Center for Molecular Imaging and Translational Medicine, Xiang An Biomedicine Laboratory, School of Public Health, Xiamen University, Xiamen, 361102, China.
Wang X; State Key Laboratory of Vaccines for Infectious Diseases, Center for Molecular Imaging and Translational Medicine, Xiang An Biomedicine Laboratory, School of Public Health, Xiamen University, Xiamen, 361102, China.
Liang Y; State Key Laboratory of Vaccines for Infectious Diseases, Center for Molecular Imaging and Translational Medicine, Xiang An Biomedicine Laboratory, School of Public Health, Xiamen University, Xiamen, 361102, China.
Hu J; HTA Co., Ltd., No. 1 Sanqiang Road, Fangshan District, Beijing, 102413, China.
Huang L; State Key Laboratory of Vaccines for Infectious Diseases, Center for Molecular Imaging and Translational Medicine, Xiang An Biomedicine Laboratory, School of Public Health, Xiamen University, Xiamen, 361102, China. .
Guo Z; State Key Laboratory of Vaccines for Infectious Diseases, Center for Molecular Imaging and Translational Medicine, Xiang An Biomedicine Laboratory, School of Public Health, Xiamen University, Xiamen, 361102, China. .
Zhang X; Theranostics and Translational Research Center, Institute of Clinical Medicine & Department of Nuclear Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, No.1 Shuaifuyuan, Dongcheng District, Beijing, 100730, China. .; Pokaż więcej
Źródło:: Journal of nanobiotechnology [J Nanobiotechnology] 2024 Mar 10; Vol. 22 (1), pp. 101. Date of Electronic Publication: 2024 Mar 10.
Typ publikacji:: Journal Article
MeSH Terms:: Radiopharmaceuticals*
Colorectal Neoplasms*/pathology
Male ; Animals ; Mice ; Gallium Radioisotopes ; Tissue Distribution ; Cell Line, Tumor

Czasopismo naukowe

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Skocz do pozycji: 17.

Tytuł:: Prediction of Human Pharmacokinetics of E0703, a Novel Radioprotective Agent, Using Physiologically Based Pharmacokinetic Modeling and an Interspecies Extrapolation Approach.
Autorzy:: Ge YX; College of Chemistry and Life Science, Beijing University of Technology, Beijing 100124, China.; Department of Pharmacology and Toxicology, Beijing Institute of Radiation Medicine, Beijing 100850, China.
Zhang Z; Department of Pharmacology and Toxicology, Beijing Institute of Radiation Medicine, Beijing 100850, China.
Yan JY; Department of Pharmacology and Toxicology, Beijing Institute of Radiation Medicine, Beijing 100850, China.
Ma ZC; Department of Pharmacology and Toxicology, Beijing Institute of Radiation Medicine, Beijing 100850, China.
Wang YG; Department of Pharmacology and Toxicology, Beijing Institute of Radiation Medicine, Beijing 100850, China.
Xiao CR; Department of Pharmacology and Toxicology, Beijing Institute of Radiation Medicine, Beijing 100850, China.
Zhuang XM; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing 100850, China.
Gao Y; College of Chemistry and Life Science, Beijing University of Technology, Beijing 100124, China.; Department of Pharmacology and Toxicology, Beijing Institute of Radiation Medicine, Beijing 100850, China.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Mar 06; Vol. 25 (5). Date of Electronic Publication: 2024 Mar 06.
Typ publikacji:: Journal Article
MeSH Terms:: Radiation-Protective Agents*
Mice ; Humans ; Animals ; Dogs ; Models, Biological ; Administration, Oral ; Tissue Distribution ; Pharmacokinetics

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Skocz do pozycji: 18.

Tytuł:: ImmunoPET imaging of TIGIT in the glioma microenvironment.
Autorzy:: Vincze SR; Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Jaswal AP; Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Frederico SC; Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Nisnboym M; Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Department of Neurology, Tel-Aviv Sourasky Medical Center, Tel-Aviv University, Tel-Aviv, Israel.
Li B; Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Xiong Z; Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Sever RE; Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Sneiderman CT; Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Rodgers M; Department of Biochemistry, University of Missouri, Columbia, MO, USA.
Day KE; In Vivo Imaging Facility, University of Pittsburgh Medical Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA.
Latoche JD; In Vivo Imaging Facility, University of Pittsburgh Medical Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA.
Foley LM; In Vivo Imaging Facility, University of Pittsburgh Medical Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA.
Hitchens TK; In Vivo Imaging Facility, University of Pittsburgh Medical Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA.; Department of Neurobiology, University of Pittsburgh, Pittsburgh, PA, USA.
Frederick R; In Vivo Imaging Facility, University of Pittsburgh Medical Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA.
Patel RB; Department of Radiology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Hadjipanayis CG; Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Raphael I; Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Nedrow JR; In Vivo Imaging Facility, University of Pittsburgh Medical Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA. .; Department of Radiology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA. .
Edwards WB; Department of Biochemistry, University of Missouri, Columbia, MO, USA. .
Kohanbash G; Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. .; Department of Immunology, University of Pittsburgh, Pittsburgh, PA, USA. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Mar 04; Vol. 14 (1), pp. 5305. Date of Electronic Publication: 2024 Mar 04.
Typ publikacji:: Journal Article
MeSH Terms:: Glioma*/diagnostic imaging
Glioblastoma*/diagnostic imaging
Humans ; Animals ; Mice ; Tissue Distribution ; Positron-Emission Tomography ; Receptors, Immunologic ; Tumor Microenvironment

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Skocz do pozycji: 19.

Tytuł:: Development of finely tuned liposome nanoplatform for macrophage depletion.
Autorzy:: Choi TH; Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, South Korea.; Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, 08826, South Korea.
Yoo RJ; Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, South Korea.; Department of Nuclear Medicine, Seoul National University Hospital, 101 Daehak-Ro, Jongno-Gu, Seoul, South Korea.; Biomedical Research Institute, Seoul National University Hospital, Seoul, South Korea.
Park JY; Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, South Korea.; Institute of Radiation Medicine, Medical Research Center, Seoul National University College of Medicine, Seoul, South Korea.
Kim JY; Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, South Korea.; Institute of Radiation Medicine, Medical Research Center, Seoul National University College of Medicine, Seoul, South Korea.
Ann YC; Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, South Korea.; School of Dentistry, Seoul National University, Seoul, South Korea.
Park J; Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, 08826, South Korea.
Kim JS; Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, South Korea.
Kim K; Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, South Korea.
Shin YJ; Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, South Korea.; Cancer Research Institute, Seoul National University College of Medicine, Seoul, South Korea.; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, South Korea.
Lee YJ; Division of Applied RI, Korea Institute of Radiological and Medical Sciences (KIRAMS), Seoul, South Korea.
Lee KC; Division of Applied RI, Korea Institute of Radiological and Medical Sciences (KIRAMS), Seoul, South Korea.
Park J; Cancer Research Institute, Seoul National University College of Medicine, Seoul, South Korea.; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, South Korea.; Department of Microbiology and Immunology, and Institute of Endemic Disease, Seoul National University College of Medicine, Seoul, South Korea.
Chung H; Cancer Research Institute, Seoul National University College of Medicine, Seoul, South Korea.; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, South Korea.; Department of Microbiology and Immunology, and Institute of Endemic Disease, Seoul National University College of Medicine, Seoul, South Korea.
Seok SH; Cancer Research Institute, Seoul National University College of Medicine, Seoul, South Korea.; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, South Korea.; Department of Microbiology and Immunology, and Institute of Endemic Disease, Seoul National University College of Medicine, Seoul, South Korea.
Im HJ; Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, 08826, South Korea. .; Institute of Radiation Medicine, Medical Research Center, Seoul National University College of Medicine, Seoul, South Korea. .; Cancer Research Institute, Seoul National University College of Medicine, Seoul, South Korea. .
Lee YS; Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, South Korea. .; Department of Nuclear Medicine, Seoul National University Hospital, 101 Daehak-Ro, Jongno-Gu, Seoul, South Korea. .; Institute of Radiation Medicine, Medical Research Center, Seoul National University College of Medicine, Seoul, South Korea. .; Cancer Research Institute, Seoul National University College of Medicine, Seoul, South Korea. .; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, South Korea. .; Pokaż więcej
Źródło:: Journal of nanobiotechnology [J Nanobiotechnology] 2024 Feb 29; Vol. 22 (1), pp. 83. Date of Electronic Publication: 2024 Feb 29.
Typ publikacji:: Journal Article
MeSH Terms:: Liposomes*/pharmacology
Clodronic Acid*/pharmacology
Male ; Humans ; Tissue Distribution ; Macrophages

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Skocz do pozycji: 20.

Tytuł:: Lu-Labeled Iron Oxide Nanoparticles Functionalized with Doxorubicin and Bevacizumab as Nanobrachytherapy Agents against Breast Cancer.
Autorzy:: Salvanou EA; Institute of Nuclear & Radiological Sciences & Technology, Energy & Safety, National Center for Scientific Research 'Demokritos', 15341 Athens, Greece.
Kolokithas-Ntoukas A; Department of Pharmacy, School of Health Sciences, University of Patras, 26504 Patras, Greece.
Prokopiou D; Laboratory of Inorganic Chemistry, Department of Chemistry, National and Kapodistrian University of Athens, Panepistimiopolis-Zografou, 15771 Athens, Greece.
Theodosiou M; Laboratory of Inorganic Chemistry, Department of Chemistry, National and Kapodistrian University of Athens, Panepistimiopolis-Zografou, 15771 Athens, Greece.
Efthimiadou E; Laboratory of Inorganic Chemistry, Department of Chemistry, National and Kapodistrian University of Athens, Panepistimiopolis-Zografou, 15771 Athens, Greece.
Koźmiński P; Centre of Radiochemistry and Nuclear Chemistry, Institute of Nuclear Chemistry and Technology, Dorodna 16 Str., 03-195 Warsaw, Poland.
Xanthopoulos S; Institute of Nuclear & Radiological Sciences & Technology, Energy & Safety, National Center for Scientific Research 'Demokritos', 15341 Athens, Greece.
Avgoustakis K; Department of Pharmacy, School of Health Sciences, University of Patras, 26504 Patras, Greece.
Bouziotis P; Institute of Nuclear & Radiological Sciences & Technology, Energy & Safety, National Center for Scientific Research 'Demokritos', 15341 Athens, Greece.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2024 Feb 27; Vol. 29 (5). Date of Electronic Publication: 2024 Feb 27.
Typ publikacji:: Journal Article
MeSH Terms:: Triple Negative Breast Neoplasms*
Nanoparticles*
Breast Neoplasms*/metabolism
Humans ; Animals ; Mice ; Female ; Bevacizumab ; Tissue Distribution ; Doxorubicin ; Magnetic Iron Oxide Nanoparticles ; Cell Line, Tumor

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