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Wyszukujesz frazę ""Tortorici MA"" wg kryterium: Autor


Tytuł:
Soft tissue volume augmentation in the oral cavity with a collagen-based 3D matrix with orientated open pore structure
Autorzy:
Damink Leon Olde
Heschel Ingo
Leemhuis Hans
Tortorici Martina
Wessing Bastian
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Temat:
biomaterials
collagen
3d matrix
soft tissue augmentation
dental implants
guided tissue regeneration
Medicine
Źródło:
Current Directions in Biomedical Engineering, Vol 4, Iss 1, Pp 237-241 (2018)
Opis pliku:
electronic resource
Relacje:
https://doaj.org/toc/2364-5504
Dostęp URL:
https://doaj.org/article/36b4ac9d9128425980380633d5722076  Link otwiera się w nowym oknie
Czasopismo naukowe
Tytuł:
Persistent immune imprinting occurs after vaccination with the COVID-19 XBB.1.5 mRNA booster in humans.
Autorzy:
Tortorici MA; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.
Addetia A; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.
Seo AJ; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.
Brown J; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.
Sprouse K; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.
Logue J; Division of Allergy and Infectious Diseases, University of Washington, Seattle, WA 98195, USA.
Clark E; Division of Allergy and Infectious Diseases, University of Washington, Seattle, WA 98195, USA.
Franko N; Division of Allergy and Infectious Diseases, University of Washington, Seattle, WA 98195, USA.
Chu H; Division of Allergy and Infectious Diseases, University of Washington, Seattle, WA 98195, USA.
Veesler D; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA; Howard Hughes Medical Institute, University of Washington, Seattle, WA 98195, USA. Electronic address: .
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Źródło:
Immunity [Immunity] 2024 Mar 08. Date of Electronic Publication: 2024 Mar 08.
Typ publikacji:
Journal Article
Czasopismo naukowe
Tytuł:
Maturation of SARS-CoV-2 Spike-specific memory B cells drives resilience to viral escape.
Autorzy:
Marzi R; Humabs BioMed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Bassi J; Humabs BioMed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Silacci-Fregni C; Humabs BioMed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Bartha I; Humabs BioMed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Muoio F; Humabs BioMed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Culap K; Humabs BioMed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Sprugasci N; Humabs BioMed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Lombardo G; Humabs BioMed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Saliba C; Humabs BioMed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Cameroni E; Humabs BioMed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Cassotta A; Institute for Research in Biomedicine, Università della Svizzera italiana, Bellinzona, Switzerland.
Low JS; Institute for Research in Biomedicine, Università della Svizzera italiana, Bellinzona, Switzerland.; Institute of Microbiology, ETH Zurich, Zurich, Switzerland.
Walls AC; Department of Biochemistry, University of Washington, Seattle, WA, USA.
McCallum M; Department of Biochemistry, University of Washington, Seattle, WA, USA.
Tortorici MA; Department of Biochemistry, University of Washington, Seattle, WA, USA.
Bowen JE; Department of Biochemistry, University of Washington, Seattle, WA, USA.
Dellota EA Jr; Vir Biotechnology, San Francisco, CA, USA.
Dillen JR; Vir Biotechnology, San Francisco, CA, USA.
Czudnochowski N; Vir Biotechnology, San Francisco, CA, USA.
Pertusini L; Division of Nephrology, Ente Ospedaliero Cantonale, Lugano, Switzerland.
Terrot T; Clinical Trial Unit, Ente Ospedaliero Cantonale, Lugano, Switzerland.
Lepori V; Independent Physician, Bellinzona, Switzerland.
Tarkowski M; Department of Biomedical and Clinical Sciences 'L. Sacco', University of Milan, Milan, Italy.
Riva A; Department of Biomedical and Clinical Sciences 'L. Sacco', University of Milan, Milan, Italy.; III Division of Infectious Diseases, ASST Fatebenefratelli Sacco, Luigi Sacco Hospital, Milan, Italy.
Biggiogero M; Clinical Research Unit, Clinica Luganese Moncucco, Lugano, Switzerland.
Franzetti-Pellanda A; Clinical Research Unit, Clinica Luganese Moncucco, Lugano, Switzerland.
Garzoni C; Clinic of Internal Medicine and Infectious Diseases, Clinica Luganese Moncucco, Lugano, Switzerland.
Ferrari P; Division of Nephrology, Ente Ospedaliero Cantonale, Lugano, Switzerland.; Faculty of Biomedical Sciences, Università della Svizzera italiana, Lugano, Switzerland.; Clinical School, University of New South Wales, Sydney, NSW, Australia.
Ceschi A; Clinical Trial Unit, Ente Ospedaliero Cantonale, Lugano, Switzerland.; Faculty of Biomedical Sciences, Università della Svizzera italiana, Lugano, Switzerland.; Division of Clinical Pharmacology and Toxicology, Institute of Pharmacological Sciences of Southern Switzerland, Ente Ospedaliero Cantonale, Lugano, Switzerland.; Department of Clinical Pharmacology and Toxicology, University Hospital Zurich, Zurich, Switzerland.
Giannini O; Faculty of Biomedical Sciences, Università della Svizzera italiana, Lugano, Switzerland.; Department of Medicine, Ente Ospedaliero Cantonale, Bellinzona, Switzerland.
Havenar-Daughton C; Vir Biotechnology, San Francisco, CA, USA.
Telenti A; Vir Biotechnology, San Francisco, CA, USA.
Arvin A; Vir Biotechnology, San Francisco, CA, USA.
Virgin HW; Vir Biotechnology, San Francisco, CA, USA.; Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA.; Department of Internal Medicine, UT Southwestern Medical Center, Dallas, TX, USA.
Sallusto F; Institute for Research in Biomedicine, Università della Svizzera italiana, Bellinzona, Switzerland.; Institute of Microbiology, ETH Zurich, Zurich, Switzerland.
Veesler D; Department of Biochemistry, University of Washington, Seattle, WA, USA.
Lanzavecchia A; Humabs BioMed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Corti D; Humabs BioMed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Piccoli L; Humabs BioMed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
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Źródło:
IScience [iScience] 2023 Jan 20; Vol. 26 (1), pp. 105726. Date of Electronic Publication: 2022 Dec 05.
Typ publikacji:
Journal Article
Czasopismo naukowe
Tytuł:
Close relatives of MERS-CoV in bats use ACE2 as their functional receptors.
Autorzy:
Xiong Q; State Key Laboratory of Virology, Institute for Vaccine Research and Modern Virology Research Center, College of Life Sciences, TaiKang Center for Life and Medical Sciences, Wuhan University, Wuhan, China.
Cao L; CAS Key Laboratory of Infection and Immunity, National Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
Ma C; State Key Laboratory of Virology, Institute for Vaccine Research and Modern Virology Research Center, College of Life Sciences, TaiKang Center for Life and Medical Sciences, Wuhan University, Wuhan, China.
Tortorici MA; Department of Biochemistry, University of Washington, Seattle, WA, USA.
Liu C; State Key Laboratory of Virology, Institute for Vaccine Research and Modern Virology Research Center, College of Life Sciences, TaiKang Center for Life and Medical Sciences, Wuhan University, Wuhan, China.
Si J; State Key Laboratory of Virology, Institute for Vaccine Research and Modern Virology Research Center, College of Life Sciences, TaiKang Center for Life and Medical Sciences, Wuhan University, Wuhan, China.
Liu P; State Key Laboratory of Virology, Institute for Vaccine Research and Modern Virology Research Center, College of Life Sciences, TaiKang Center for Life and Medical Sciences, Wuhan University, Wuhan, China.
Gu M; State Key Laboratory of Virology, Institute for Vaccine Research and Modern Virology Research Center, College of Life Sciences, TaiKang Center for Life and Medical Sciences, Wuhan University, Wuhan, China.
Walls AC; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Howard Hughes Medical Institute, Seattle, WA, USA.
Wang C; State Key Laboratory of Virology, Institute for Vaccine Research and Modern Virology Research Center, College of Life Sciences, TaiKang Center for Life and Medical Sciences, Wuhan University, Wuhan, China.
Shi L; State Key Laboratory of Virology, Institute for Vaccine Research and Modern Virology Research Center, College of Life Sciences, TaiKang Center for Life and Medical Sciences, Wuhan University, Wuhan, China.
Tong F; State Key Laboratory of Virology, Institute for Vaccine Research and Modern Virology Research Center, College of Life Sciences, TaiKang Center for Life and Medical Sciences, Wuhan University, Wuhan, China.
Huang M; State Key Laboratory of Virology, Institute for Vaccine Research and Modern Virology Research Center, College of Life Sciences, TaiKang Center for Life and Medical Sciences, Wuhan University, Wuhan, China.
Li J; State Key Laboratory of Virology, Institute for Vaccine Research and Modern Virology Research Center, College of Life Sciences, TaiKang Center for Life and Medical Sciences, Wuhan University, Wuhan, China.
Zhao C; State Key Laboratory of Virology, Institute for Vaccine Research and Modern Virology Research Center, College of Life Sciences, TaiKang Center for Life and Medical Sciences, Wuhan University, Wuhan, China.
Shen C; State Key Laboratory of Virology, Institute for Vaccine Research and Modern Virology Research Center, College of Life Sciences, TaiKang Center for Life and Medical Sciences, Wuhan University, Wuhan, China.
Chen Y; State Key Laboratory of Virology, Institute for Vaccine Research and Modern Virology Research Center, College of Life Sciences, TaiKang Center for Life and Medical Sciences, Wuhan University, Wuhan, China.
Zhao H; Department of Ecology, Tibetan Centre for Ecology and Conservation at WHU-TU, Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan, China.
Lan K; State Key Laboratory of Virology, Institute for Vaccine Research and Modern Virology Research Center, College of Life Sciences, TaiKang Center for Life and Medical Sciences, Wuhan University, Wuhan, China.
Corti D; Humabs BioMed SA, subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Veesler D; Department of Biochemistry, University of Washington, Seattle, WA, USA. .; Howard Hughes Medical Institute, Seattle, WA, USA. .
Wang X; CAS Key Laboratory of Infection and Immunity, National Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China. .; University of Chinese Academy of Sciences, Beijing, China. .
Yan H; State Key Laboratory of Virology, Institute for Vaccine Research and Modern Virology Research Center, College of Life Sciences, TaiKang Center for Life and Medical Sciences, Wuhan University, Wuhan, China. .
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Źródło:
Nature [Nature] 2022 Dec; Vol. 612 (7941), pp. 748-757. Date of Electronic Publication: 2022 Dec 07.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
Angiotensin-Converting Enzyme 2*/metabolism
Chiroptera*/metabolism
Chiroptera*/virology
Middle East Respiratory Syndrome Coronavirus*/classification
Middle East Respiratory Syndrome Coronavirus*/isolation & purification
Middle East Respiratory Syndrome Coronavirus*/metabolism
Receptors, Virus*/metabolism
Virus Internalization*
Animals ; Humans ; Cryoelectron Microscopy ; Protein Binding ; Spike Glycoprotein, Coronavirus/chemistry ; Spike Glycoprotein, Coronavirus/metabolism ; Dipeptidyl Peptidase 4/metabolism ; Viral Zoonoses
Czasopismo naukowe
Tytuł:
Effect of CSL112 (apolipoprotein A-I [human]) on cholesterol efflux capacity in Japanese subjects: Findings from a phase I study and a cross-study comparison.
Autorzy:
Zheng B; CSL Behring, King of Prussia, Pennsylvania, USA.
Goto S; Department of Medicine (Cardiology), Tokai University School of Medicine, Isehara, Japan.
Clementi R; CSL Behring, King of Prussia, Pennsylvania, USA.
Feaster J; CSL Behring, King of Prussia, Pennsylvania, USA.
Duffy D; CSL Behring, King of Prussia, Pennsylvania, USA.
Dalitz P; CSL Limited, Parkville, Victoria, Australia.
Airey J; CSL Limited, Parkville, Victoria, Australia.
Korjian S; Division of Cardiovascular Medicine, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
Tortorici MA; CSL Behring, King of Prussia, Pennsylvania, USA.
Roberts J; CSL Behring, King of Prussia, Pennsylvania, USA.
Gibson CM; PERFUSE Study Group, Cardiovascular Division, Departments of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
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Źródło:
Clinical and translational science [Clin Transl Sci] 2022 Oct; Vol. 15 (10), pp. 2331-2341. Date of Electronic Publication: 2022 Aug 07.
Typ publikacji:
Randomized Controlled Trial; Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apolipoprotein A-I*/pharmacokinetics
Lipoproteins, HDL*
Humans ; Biological Transport ; Cholesterol ; Double-Blind Method
Czasopismo naukowe
Tytuł:
ACE2-binding exposes the SARS-CoV-2 fusion peptide to broadly neutralizing coronavirus antibodies.
Autorzy:
Low JS; Institute for Research in Biomedicine, Università della Svizzera Italiana, 6500 Bellinzona, Switzerland.; Institute of Microbiology, ETH Zürich, 8093 Zurich, Switzerland.
Jerak J; Institute for Research in Biomedicine, Università della Svizzera Italiana, 6500 Bellinzona, Switzerland.; Institute of Microbiology, ETH Zürich, 8093 Zurich, Switzerland.
Tortorici MA; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.
McCallum M; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.
Pinto D; Humabs BioMed SA (subsidiary of Vir Biotechnology), 6500 Bellinzona, Switzerland.
Cassotta A; Institute for Research in Biomedicine, Università della Svizzera Italiana, 6500 Bellinzona, Switzerland.
Foglierini M; Institute for Research in Biomedicine, Università della Svizzera Italiana, 6500 Bellinzona, Switzerland.
Mele F; Institute for Research in Biomedicine, Università della Svizzera Italiana, 6500 Bellinzona, Switzerland.
Abdelnabi R; KU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, B-3000 Leuven, Belgium.
Weynand B; KU Leuven Department of Imaging and Pathology, Translational Cell and Tissue Research, B-3000 Leuven, Belgium.
Noack J; Vir Biotechnology, San Francisco, CA 94158, USA.
Montiel-Ruiz M; Vir Biotechnology, San Francisco, CA 94158, USA.
Bianchi S; Humabs BioMed SA (subsidiary of Vir Biotechnology), 6500 Bellinzona, Switzerland.
Benigni F; Humabs BioMed SA (subsidiary of Vir Biotechnology), 6500 Bellinzona, Switzerland.
Sprugasci N; Humabs BioMed SA (subsidiary of Vir Biotechnology), 6500 Bellinzona, Switzerland.
Joshi A; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.
Bowen JE; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.
Stewart C; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.
Rexhepaj M; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.
Walls AC; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.; Howard Hughes Medical Institute, Seattle, WA 98195, USA.
Jarrossay D; Institute for Research in Biomedicine, Università della Svizzera Italiana, 6500 Bellinzona, Switzerland.
Morone D; Institute for Research in Biomedicine, Università della Svizzera Italiana, 6500 Bellinzona, Switzerland.
Paparoditis P; Institute for Research in Biomedicine, Università della Svizzera Italiana, 6500 Bellinzona, Switzerland.
Garzoni C; Clinic of Internal Medicine and Infectious Diseases, Clinica Luganese Moncucco, 6900 Lugano, Switzerland.
Ferrari P; Faculty of Biomedical Sciences, Università della Svizzera Italiana, 6900 Lugano, Switzerland.; Department of Internal Medicine, Ente Ospedaliero Cantonale, 6500 Bellinzona, Switzerland.; Prince of Wales Hospital Clinical School, University of New South Wales, Sydney, New South Wales 2052, Australia.
Ceschi A; Faculty of Biomedical Sciences, Università della Svizzera Italiana, 6900 Lugano, Switzerland.; Division of Clinical Pharmacology and Toxicology, Institute of Pharmacological Sciences of Southern Switzerland, Ente Ospedaliero Cantonale, 6900 Lugano, Switzerland.; Clinical Trial Unit, Ente Ospedaliero Cantonale, 6500 Bellinzona, Switzerland.; Department of Clinical Pharmacology and Toxicology, University Hospital Zurich, 8091 Zurich, Switzerland.
Neyts J; KU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, B-3000 Leuven, Belgium.; Global Virus Network, Baltimore, MD 21201, USA.
Purcell LA; Vir Biotechnology, San Francisco, CA 94158, USA.
Snell G; Vir Biotechnology, San Francisco, CA 94158, USA.
Corti D; Humabs BioMed SA (subsidiary of Vir Biotechnology), 6500 Bellinzona, Switzerland.
Lanzavecchia A; Humabs BioMed SA (subsidiary of Vir Biotechnology), 6500 Bellinzona, Switzerland.; National Institute of Molecular Genetics, 20122 Milano, Italy.
Veesler D; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.; Howard Hughes Medical Institute, Seattle, WA 98195, USA.
Sallusto F; Institute for Research in Biomedicine, Università della Svizzera Italiana, 6500 Bellinzona, Switzerland.; Institute of Microbiology, ETH Zürich, 8093 Zurich, Switzerland.
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Źródło:
Science (New York, N.Y.) [Science] 2022 Aug 12; Vol. 377 (6607), pp. 735-742. Date of Electronic Publication: 2022 Jul 12.
Typ publikacji:
Journal Article
MeSH Terms:
Angiotensin-Converting Enzyme 2*/chemistry
Antibodies, Monoclonal*/immunology
Antibodies, Monoclonal*/isolation & purification
Antibodies, Viral*/immunology
Antibodies, Viral*/isolation & purification
Broadly Neutralizing Antibodies*/immunology
COVID-19*/immunology
SARS-CoV-2*/immunology
Spike Glycoprotein, Coronavirus*/chemistry
Spike Glycoprotein, Coronavirus*/immunology
Animals ; Humans ; Peptides/immunology ; Protein Binding
Czasopismo naukowe
Tytuł:
Author Correction: Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies.
Autorzy:
Collier DA; Cambridge Institute of Therapeutic Immunology & Infectious Disease, Cambridge, UK.; Department of Medicine, University of Cambridge, Cambridge, UK.; Division of Infection and Immunity, University College London, London, UK.
De Marco A; Humabs Biomed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Ferreira IATM; Cambridge Institute of Therapeutic Immunology & Infectious Disease, Cambridge, UK.; Department of Medicine, University of Cambridge, Cambridge, UK.
Meng B; Cambridge Institute of Therapeutic Immunology & Infectious Disease, Cambridge, UK.; Department of Medicine, University of Cambridge, Cambridge, UK.
Datir RP; Cambridge Institute of Therapeutic Immunology & Infectious Disease, Cambridge, UK.; Department of Medicine, University of Cambridge, Cambridge, UK.; Division of Infection and Immunity, University College London, London, UK.
Walls AC; Department of Biochemistry, University of Washington, Seattle, WA, USA.
Kemp SA; Cambridge Institute of Therapeutic Immunology & Infectious Disease, Cambridge, UK.; Department of Medicine, University of Cambridge, Cambridge, UK.; Division of Infection and Immunity, University College London, London, UK.
Bassi J; Humabs Biomed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Pinto D; Humabs Biomed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Silacci-Fregni C; Humabs Biomed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Bianchi S; Humabs Biomed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Tortorici MA; Department of Biochemistry, University of Washington, Seattle, WA, USA.
Bowen J; Department of Biochemistry, University of Washington, Seattle, WA, USA.
Culap K; Humabs Biomed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Jaconi S; Humabs Biomed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Cameroni E; Humabs Biomed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Snell G; Vir Biotechnology, San Francisco, CA, USA.
Pizzuto MS; Humabs Biomed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Pellanda AF; Clinic of Internal Medicine and Infectious Diseases, Clinica Luganese Moncucco, Lugano, Switzerland.
Garzoni C; Clinic of Internal Medicine and Infectious Diseases, Clinica Luganese Moncucco, Lugano, Switzerland.
Riva A; Division of Infectious Diseases, Luigi Sacco Hospital, University of Milan, Milan, Italy.
Elmer A; NIHR Cambridge Clinical Research Facility, Cambridge, UK.
Kingston N; NIHR Bioresource, Cambridge, UK.
Graves B; NIHR Bioresource, Cambridge, UK.
McCoy LE; Division of Infection and Immunity, University College London, London, UK.
Smith KGC; Cambridge Institute of Therapeutic Immunology & Infectious Disease, Cambridge, UK.; Department of Medicine, University of Cambridge, Cambridge, UK.
Bradley JR; Department of Medicine, University of Cambridge, Cambridge, UK.; NIHR Bioresource, Cambridge, UK.
Temperton N; University of Kent, Canturbury, UK.
Ceron-Gutierrez L; Department of Clinical Biochemistry and Immunology, Addenbrooke's Hospital, Cambridge, UK.
Barcenas-Morales G; Department of Clinical Biochemistry and Immunology, Addenbrooke's Hospital, Cambridge, UK.; Laboratorio de Inmunologia, UNAM, Cuautitlán, Mexico.
Harvey W; Institute of Biodiversity, University of Glasgow, Glasgow, UK.
Virgin HW; Vir Biotechnology, San Francisco, CA, USA.
Lanzavecchia A; Humabs Biomed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Piccoli L; Humabs Biomed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Doffinger R; Department of Clinical Biochemistry and Immunology, Addenbrooke's Hospital, Cambridge, UK.; Department of Haematology, University of Cambridge, Cambridge, UK.
Wills M; Department of Medicine, University of Cambridge, Cambridge, UK.
Veesler D; Department of Biochemistry, University of Washington, Seattle, WA, USA.
Corti D; Humabs Biomed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland. .
Gupta RK; Cambridge Institute of Therapeutic Immunology & Infectious Disease, Cambridge, UK. .; Department of Medicine, University of Cambridge, Cambridge, UK. .; Department of Haematology, University of Cambridge, Cambridge, UK. .; University of KwaZulu Natal, Durban, South Africa. .; Africa Health Research Institute, Durban, South Africa. .; Department of Infectious Diseases, Cambridge University Hospitals NHS Trust, Cambridge, UK. .
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Corporate Authors:
CITIID-NIHR BioResource COVID-19 Collaboration
COVID-19 Genomics UK (COG-UK) Consortium
Źródło:
Nature [Nature] 2022 Aug; Vol. 608 (7922), pp. E24.
Typ publikacji:
Published Erratum
Tytuł:
Structure, receptor recognition, and antigenicity of the human coronavirus CCoV-HuPn-2018 spike glycoprotein.
Autorzy:
Tortorici MA; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.
Walls AC; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA; Howard Hughes Medical Institute, University of Washington, Seattle, WA 98195, USA.
Joshi A; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.
Park YJ; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.
Eguia RT; Basic Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
Miranda MC; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA; Institute for Protein Design, University of Washington, Seattle, WA 98195, USA.
Kepl E; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA; Institute for Protein Design, University of Washington, Seattle, WA 98195, USA.
Dosey A; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA; Institute for Protein Design, University of Washington, Seattle, WA 98195, USA.
Stevens-Ayers T; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
Boeckh MJ; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
Telenti A; Vir Biotechnology, San Francisco, CA 94158, USA.
Lanzavecchia A; Istituto Nazionale Genetica Molecolare, 20122 Milano, Italy; Humabs Biomed SA-a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.
King NP; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA; Institute for Protein Design, University of Washington, Seattle, WA 98195, USA.
Corti D; Humabs Biomed SA-a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.
Bloom JD; Basic Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
Veesler D; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA; Howard Hughes Medical Institute, University of Washington, Seattle, WA 98195, USA. Electronic address: .
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Źródło:
Cell [Cell] 2022 Jun 23; Vol. 185 (13), pp. 2279-2291.e17. Date of Electronic Publication: 2022 May 27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
Coronavirus*/metabolism
Coronavirus 229E, Human*/metabolism
Coronavirus Infections*
Animals ; CD13 Antigens/chemistry ; CD13 Antigens/metabolism ; Cats ; Cell Line ; Dogs ; Humans ; Receptors, Virus/metabolism ; Spike Glycoprotein, Coronavirus/metabolism ; Swine
Czasopismo naukowe
Tytuł:
Elicitation of broadly protective sarbecovirus immunity by receptor-binding domain nanoparticle vaccines.
Autorzy:
Walls AC; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.
Miranda MC; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA; Institute for Protein Design, University of Washington, Seattle, WA 98195, USA.
Schäfer A; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27514, USA.
Pham MN; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA; Institute for Protein Design, University of Washington, Seattle, WA 98195, USA.
Greaney A; Basic Sciences and Computational Biology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA; Department of Genome Sciences, University of Washington, Seattle, WA 98109, USA.
Arunachalam PS; Institute for Immunity, Transplantation and Infection, Stanford University School of Medicine, Stanford University, Stanford, CA, USA.
Navarro MJ; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.
Tortorici MA; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA; Institut Pasteur and CNRS UMR 3569, Unité de Virologie Structurale, Paris, France.
Rogers K; New Iberia Research Center and Department of Biology, University of Louisiana at Lafayette, New Iberia, LA 70560, USA.
O'Connor MA; Washington National Primate Research Center, Seattle, WA 98121, USA; Department of Microbiology, University of Washington, Seattle, WA 98195, USA.
Shirreff L; New Iberia Research Center and Department of Biology, University of Louisiana at Lafayette, New Iberia, LA 70560, USA.
Ferrell DE; New Iberia Research Center and Department of Biology, University of Louisiana at Lafayette, New Iberia, LA 70560, USA.
Bowen J; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.
Brunette N; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA; Institute for Protein Design, University of Washington, Seattle, WA 98195, USA.
Kepl E; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA; Institute for Protein Design, University of Washington, Seattle, WA 98195, USA.
Zepeda SK; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.
Starr T; Basic Sciences and Computational Biology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
Hsieh CL; Department of Molecular Biosciences, The University of Texas at Austin, Austin, TX 78712, USA.
Fiala B; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA; Institute for Protein Design, University of Washington, Seattle, WA 98195, USA.
Wrenn S; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA; Institute for Protein Design, University of Washington, Seattle, WA 98195, USA.
Pettie D; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA; Institute for Protein Design, University of Washington, Seattle, WA 98195, USA.
Sydeman C; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA; Institute for Protein Design, University of Washington, Seattle, WA 98195, USA.
Sprouse KR; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.
Johnson M; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA; Institute for Protein Design, University of Washington, Seattle, WA 98195, USA.
Blackstone A; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA; Institute for Protein Design, University of Washington, Seattle, WA 98195, USA.
Ravichandran R; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA; Institute for Protein Design, University of Washington, Seattle, WA 98195, USA.
Ogohara C; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA; Institute for Protein Design, University of Washington, Seattle, WA 98195, USA.
Carter L; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA; Institute for Protein Design, University of Washington, Seattle, WA 98195, USA.
Tilles SW; Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington School of Medicine, Seattle, WA 98195, USA.
Rappuoli R; GSK, Siena, Italy.
Leist SR; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27514, USA.
Martinez DR; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27514, USA.
Clark M; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27514, USA.
Tisch R; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27514, USA.
O'Hagan DT; GSK, Rockville, MD, USA.
Van Der Most R; GSK, Rixensart, Belgium.
Van Voorhis WC; Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington School of Medicine, Seattle, WA 98195, USA.
Corti D; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.
McLellan JS; Department of Molecular Biosciences, The University of Texas at Austin, Austin, TX 78712, USA.
Kleanthous H; Bill & Melinda Gates Foundation, Seattle, WA 98109, USA.
Sheahan TP; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27514, USA.
Smith KD; UW Medicine Department of Laboratory Medicine and Pathology, Seattle, WA 98195, USA.
Fuller DH; Washington National Primate Research Center, Seattle, WA 98121, USA; Department of Microbiology, University of Washington, Seattle, WA 98195, USA.
Villinger F; New Iberia Research Center and Department of Biology, University of Louisiana at Lafayette, New Iberia, LA 70560, USA.
Bloom J; Basic Sciences and Computational Biology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA; Department of Genome Sciences, University of Washington, Seattle, WA 98109, USA.
Pulendran B; Institute for Immunity, Transplantation and Infection, Stanford University School of Medicine, Stanford University, Stanford, CA, USA.
Baric RS; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27514, USA.
King NP; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA; Institute for Protein Design, University of Washington, Seattle, WA 98195, USA. Electronic address: .
Veesler D; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA. Electronic address: .
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Źródło:
Cell [Cell] 2021 Oct 14; Vol. 184 (21), pp. 5432-5447.e16. Date of Electronic Publication: 2021 Sep 15.
Typ publikacji:
Journal Article
Czasopismo naukowe
Tytuł:
Broad betacoronavirus neutralization by a stem helix-specific human antibody.
Autorzy:
Pinto D; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.
Sauer MM; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.
Czudnochowski N; Vir Biotechnology, San Francisco, CA 94158, USA.
Low JS; Institute for Research in Biomedicine, Università della Svizzera italiana, 6500 Bellinzona, Switzerland.
Tortorici MA; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.
Housley MP; Vir Biotechnology, San Francisco, CA 94158, USA.
Noack J; Vir Biotechnology, San Francisco, CA 94158, USA.
Walls AC; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.
Bowen JE; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.
Guarino B; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.
Rosen LE; Vir Biotechnology, San Francisco, CA 94158, USA.
di Iulio J; Vir Biotechnology, San Francisco, CA 94158, USA.
Jerak J; Institute for Research in Biomedicine, Università della Svizzera italiana, 6500 Bellinzona, Switzerland.
Kaiser H; Vir Biotechnology, San Francisco, CA 94158, USA.
Islam S; Vir Biotechnology, San Francisco, CA 94158, USA.
Jaconi S; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.
Sprugasci N; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.
Culap K; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.
Abdelnabi R; Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, KU Leuven, 3000 Leuven, Belgium.
Foo C; Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, KU Leuven, 3000 Leuven, Belgium.
Coelmont L; Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, KU Leuven, 3000 Leuven, Belgium.
Bartha I; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.
Bianchi S; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.
Silacci-Fregni C; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.
Bassi J; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.
Marzi R; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.
Vetti E; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.
Cassotta A; Institute for Research in Biomedicine, Università della Svizzera italiana, 6500 Bellinzona, Switzerland.
Ceschi A; Clinical Trial Unit, Ente Ospedaliero Cantonale, 6900 Lugano, Switzerland.; Division of Clinical Pharmacology and Toxicology, Institute of Pharmacological Sciences of Southern Switzerland, Ente Ospedaliero Cantonale, 6900 Lugano, Switzerland.; Department of Clinical Pharmacology and Toxicology, University Hospital Zurich, 8091 Zurich, Switzerland.; Faculty of Biomedical Sciences, Università della Svizzera italiana, 6900 Lugano, Switzerland.
Ferrari P; Faculty of Biomedical Sciences, Università della Svizzera italiana, 6900 Lugano, Switzerland.; Department of Medicine, Ente Ospedaliero Cantonale, 6500 Bellinzona, Switzerland.; Clinical School, University of New South Wales, Sydney, NSW, 2052, Australia.
Cippà PE; Department of Medicine, Ente Ospedaliero Cantonale, 6500 Bellinzona, Switzerland.; Faculty of Medicine, University of Zurich, 8057 Zurich, Switzerland.
Giannini O; Faculty of Biomedical Sciences, Università della Svizzera italiana, 6900 Lugano, Switzerland.; Department of Medicine, Ente Ospedaliero Cantonale, 6500 Bellinzona, Switzerland.
Ceruti S; Intensive Care Unit, Clinica Luganese Moncucco, 6900 Lugano, Switzerland.
Garzoni C; Clinic of Internal Medicine and Infectious Diseases, Clinica Luganese Moncucco, 6900 Lugano, Switzerland.
Riva A; III Division of Infectious Diseases, ASST Fatebenefratelli Sacco, Luigi Sacco Hospital, 20157 Milan, Italy.
Benigni F; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.
Cameroni E; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.
Piccoli L; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.
Pizzuto MS; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.
Smithey M; Vir Biotechnology, San Francisco, CA 94158, USA.
Hong D; Vir Biotechnology, San Francisco, CA 94158, USA.
Telenti A; Vir Biotechnology, San Francisco, CA 94158, USA.
Lempp FA; Vir Biotechnology, San Francisco, CA 94158, USA.
Neyts J; Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, KU Leuven, 3000 Leuven, Belgium.
Havenar-Daughton C; Vir Biotechnology, San Francisco, CA 94158, USA.
Lanzavecchia A; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.
Sallusto F; Institute for Research in Biomedicine, Università della Svizzera italiana, 6500 Bellinzona, Switzerland.; Institute of Microbiology, ETH Zurich, 8093 Zurich, Switzerland.
Snell G; Vir Biotechnology, San Francisco, CA 94158, USA.
Virgin HW; Vir Biotechnology, San Francisco, CA 94158, USA.; UT Southwestern Medical Center, Dallas, TX 75390, USA.; Washington University School of Medicine, St. Louis, MO 63110, USA.
Beltramello M; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.
Corti D; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.
Veesler D; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.
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Źródło:
Science (New York, N.Y.) [Science] 2021 Sep 03; Vol. 373 (6559), pp. 1109-1116. Date of Electronic Publication: 2021 Aug 06.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Virus Internalization*
Antibodies, Monoclonal/*immunology
Antibodies, Neutralizing/*immunology
Betacoronavirus/*immunology
Spike Glycoprotein, Coronavirus/*chemistry
Spike Glycoprotein, Coronavirus/*immunology
Viral Vaccines/*immunology
Animals ; Antibodies, Monoclonal/isolation & purification ; Antibodies, Neutralizing/isolation & purification ; Convalescence ; Cricetinae ; Cross Reactions ; Humans ; Immunoglobulin Fab Fragments/immunology ; Immunoglobulin Fc Fragments/immunology ; Jurkat Cells ; Lung/immunology ; Membrane Fusion/immunology ; Neutralization Tests ; Peptide Mapping ; Protein Conformation, alpha-Helical ; SARS-CoV-2/immunology ; Spike Glycoprotein, Coronavirus/genetics ; Viral Load/immunology
Czasopismo naukowe
Tytuł:
SARS-CoV-2 RBD antibodies that maximize breadth and resistance to escape.
Autorzy:
Starr TN; Basic Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Czudnochowski N; Vir Biotechnology, San Francisco, CA, USA.
Liu Z; Department of Molecular Microbiology, Washington University School of Medicine, St Louis, MO, USA.
Zatta F; Humabs BioMed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Park YJ; Department of Biochemistry, University of Washington, Seattle, WA, USA.
Addetia A; Basic Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Pinto D; Humabs BioMed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Beltramello M; Humabs BioMed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Hernandez P; Vir Biotechnology, San Francisco, CA, USA.
Greaney AJ; Basic Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.; Department of Genome Sciences, University of Washington, Seattle, WA, USA.
Marzi R; Humabs BioMed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Glass WG; Computational and Systems Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Zhang I; Computational and Systems Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Tri-Institutional PhD Program in Computational Biology and Medicine, Weill Cornell Graduate School of Medical Sciences, New York, NY, USA.
Dingens AS; Basic Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Bowen JE; Department of Biochemistry, University of Washington, Seattle, WA, USA.
Tortorici MA; Department of Biochemistry, University of Washington, Seattle, WA, USA.
Walls AC; Department of Biochemistry, University of Washington, Seattle, WA, USA.
Wojcechowskyj JA; Vir Biotechnology, San Francisco, CA, USA.
De Marco A; Humabs BioMed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Rosen LE; Vir Biotechnology, San Francisco, CA, USA.
Zhou J; Vir Biotechnology, San Francisco, CA, USA.
Montiel-Ruiz M; Vir Biotechnology, San Francisco, CA, USA.
Kaiser H; Vir Biotechnology, San Francisco, CA, USA.
Dillen JR; Vir Biotechnology, San Francisco, CA, USA.
Tucker H; Vir Biotechnology, San Francisco, CA, USA.
Bassi J; Humabs BioMed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Silacci-Fregni C; Humabs BioMed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Housley MP; Vir Biotechnology, San Francisco, CA, USA.
di Iulio J; Vir Biotechnology, San Francisco, CA, USA.
Lombardo G; Humabs BioMed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Agostini M; Vir Biotechnology, San Francisco, CA, USA.
Sprugasci N; Humabs BioMed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Culap K; Humabs BioMed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Jaconi S; Humabs BioMed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Meury M; Vir Biotechnology, San Francisco, CA, USA.
Dellota E Jr; Vir Biotechnology, San Francisco, CA, USA.
Abdelnabi R; Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, KU Leuven, Leuven, Belgium.
Foo SC; Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, KU Leuven, Leuven, Belgium.
Cameroni E; Humabs BioMed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Stumpf S; Department of Molecular Microbiology, Washington University School of Medicine, St Louis, MO, USA.
Croll TI; Cambridge Institute for Medical Research, Department of Haematology, University of Cambridge, Cambridge, UK.
Nix JC; Molecular Biology Consortium, Advanced Light Source, Lawrence Berkeley National Laboratory, Berkeley, CA, USA.
Havenar-Daughton C; Vir Biotechnology, San Francisco, CA, USA.
Piccoli L; Humabs BioMed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Benigni F; Humabs BioMed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Neyts J; Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, KU Leuven, Leuven, Belgium.
Telenti A; Vir Biotechnology, San Francisco, CA, USA.
Lempp FA; Vir Biotechnology, San Francisco, CA, USA.
Pizzuto MS; Humabs BioMed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Chodera JD; Computational and Systems Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Hebner CM; Vir Biotechnology, San Francisco, CA, USA.
Virgin HW; Vir Biotechnology, San Francisco, CA, USA.; Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA.; Department of Internal Medicine, UT Southwestern Medical Center, Dallas, TX, USA.
Whelan SPJ; Department of Molecular Microbiology, Washington University School of Medicine, St Louis, MO, USA.
Veesler D; Department of Biochemistry, University of Washington, Seattle, WA, USA.
Corti D; Humabs BioMed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland. .
Bloom JD; Basic Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA. .; Department of Genome Sciences, University of Washington, Seattle, WA, USA. .; Howard Hughes Medical Institute, Seattle, WA, USA. .
Snell G; Vir Biotechnology, San Francisco, CA, USA. .
Pokaż więcej
Źródło:
Nature [Nature] 2021 Sep; Vol. 597 (7874), pp. 97-102. Date of Electronic Publication: 2021 Jul 14.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Immune Evasion*/genetics
Immune Evasion*/immunology
Broadly Neutralizing Antibodies/*immunology
COVID-19/*virology
Cross Reactions/*immunology
SARS-CoV-2/*classification
SARS-CoV-2/*immunology
Spike Glycoprotein, Coronavirus/*chemistry
Spike Glycoprotein, Coronavirus/*immunology
Adult ; Aged ; Animals ; Antibodies, Monoclonal/chemistry ; Antibodies, Monoclonal/immunology ; Antibodies, Viral/chemistry ; Antibodies, Viral/immunology ; Antibody Affinity ; Broadly Neutralizing Antibodies/chemistry ; COVID-19/immunology ; COVID-19 Vaccines/chemistry ; COVID-19 Vaccines/immunology ; Cell Line ; Cricetinae ; Epitopes, B-Lymphocyte/chemistry ; Epitopes, B-Lymphocyte/genetics ; Epitopes, B-Lymphocyte/immunology ; Female ; Humans ; Male ; Mesocricetus ; Middle Aged ; Models, Molecular ; SARS-CoV-2/chemistry ; SARS-CoV-2/genetics ; Spike Glycoprotein, Coronavirus/genetics ; Vaccinology ; COVID-19 Drug Treatment
Czasopismo naukowe
Tytuł:
Broad sarbecovirus neutralization by a human monoclonal antibody.
Autorzy:
Tortorici MA; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Institut Pasteur and CNRS UMR 3569, Unité de Virologie Structurale, Paris, France.
Czudnochowski N; Vir Biotechnology, San Francisco, CA, USA.
Starr TN; Basic Sciences Division and Computational Biology Program, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Marzi R; Humabs Biomed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Walls AC; Department of Biochemistry, University of Washington, Seattle, WA, USA.
Zatta F; Humabs Biomed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Bowen JE; Department of Biochemistry, University of Washington, Seattle, WA, USA.
Jaconi S; Humabs Biomed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Di Iulio J; Vir Biotechnology, San Francisco, CA, USA.
Wang Z; Department of Biochemistry, University of Washington, Seattle, WA, USA.
De Marco A; Humabs Biomed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Zepeda SK; Department of Biochemistry, University of Washington, Seattle, WA, USA.
Pinto D; Humabs Biomed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Liu Z; Department of Molecular Microbiology, Washington University School of Medicine, St Louis, MO, USA.
Beltramello M; Humabs Biomed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Bartha I; Humabs Biomed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Housley MP; Vir Biotechnology, San Francisco, CA, USA.
Lempp FA; Vir Biotechnology, San Francisco, CA, USA.
Rosen LE; Vir Biotechnology, San Francisco, CA, USA.
Dellota E Jr; Vir Biotechnology, San Francisco, CA, USA.
Kaiser H; Vir Biotechnology, San Francisco, CA, USA.
Montiel-Ruiz M; Vir Biotechnology, San Francisco, CA, USA.
Zhou J; Vir Biotechnology, San Francisco, CA, USA.
Addetia A; Basic Sciences Division and Computational Biology Program, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Guarino B; Vir Biotechnology, San Francisco, CA, USA.
Culap K; Humabs Biomed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Sprugasci N; Humabs Biomed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Saliba C; Humabs Biomed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Vetti E; Humabs Biomed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Giacchetto-Sasselli I; Humabs Biomed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Fregni CS; Humabs Biomed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Abdelnabi R; Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, KU Leuven, Leuven, Belgium.
Foo SC; Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, KU Leuven, Leuven, Belgium.
Havenar-Daughton C; Vir Biotechnology, San Francisco, CA, USA.
Schmid MA; Humabs Biomed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Benigni F; Humabs Biomed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Cameroni E; Humabs Biomed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
Neyts J; Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, KU Leuven, Leuven, Belgium.
Telenti A; Vir Biotechnology, San Francisco, CA, USA.
Virgin HW; Vir Biotechnology, San Francisco, CA, USA.
Whelan SPJ; Department of Molecular Microbiology, Washington University School of Medicine, St Louis, MO, USA.
Snell G; Vir Biotechnology, San Francisco, CA, USA.
Bloom JD; Basic Sciences Division and Computational Biology Program, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.; Howard Hughes Medical Institute, Seattle, WA, USA.
Corti D; Humabs Biomed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland. .
Veesler D; Department of Biochemistry, University of Washington, Seattle, WA, USA. .
Pizzuto MS; Humabs Biomed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland. .
Pokaż więcej
Źródło:
Nature [Nature] 2021 Sep; Vol. 597 (7874), pp. 103-108. Date of Electronic Publication: 2021 Jul 19.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Antibodies, Monoclonal/*immunology
Antibodies, Monoclonal/*therapeutic use
Antibodies, Viral/*immunology
Broadly Neutralizing Antibodies/*immunology
Broadly Neutralizing Antibodies/*therapeutic use
COVID-19/*prevention & control
SARS-CoV-2/*classification
SARS-CoV-2/*immunology
Animals ; Antibodies, Monoclonal/chemistry ; Antibodies, Viral/chemistry ; Antibodies, Viral/therapeutic use ; Broadly Neutralizing Antibodies/chemistry ; COVID-19/immunology ; COVID-19/virology ; Cross Reactions/immunology ; Disease Models, Animal ; Female ; Humans ; Immune Evasion/genetics ; Immune Evasion/immunology ; Mesocricetus/immunology ; Mesocricetus/virology ; Mutation ; Neutralization Tests ; SARS-CoV-2/chemistry ; SARS-CoV-2/genetics ; Viral Zoonoses/immunology ; Viral Zoonoses/prevention & control ; Viral Zoonoses/virology
Czasopismo naukowe

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