Autor: "Townsley DM" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Telomerase enzyme deficiency promotes metabolic dysfunction in murine hepatocytes upon dietary stress.
Autorzy:: Alves-Paiva RM; Department of Internal Medicine, Ribeirão Preto School of Medicine, University of São Paulo, Ribeirão Preto, SP, Brazil.; Center for Cell-based Therapy, São Paulo Research Foundation (FAPESP), Ribeirão Preto, SP, Brazil.; Hematology Branch, National Heart, Lung, and Blood Institute, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA.
Kajigaya S; Hematology Branch, National Heart, Lung, and Blood Institute, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA.
Feng X; Hematology Branch, National Heart, Lung, and Blood Institute, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA.
Chen J; Hematology Branch, National Heart, Lung, and Blood Institute, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA.
Desierto M; Hematology Branch, National Heart, Lung, and Blood Institute, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA.
Wong S; Hematology Branch, National Heart, Lung, and Blood Institute, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA.
Townsley DM; Hematology Branch, National Heart, Lung, and Blood Institute, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA.
Donaires FS; Center for Cell-based Therapy, São Paulo Research Foundation (FAPESP), Ribeirão Preto, SP, Brazil.
Bertola A; Laboratory for Liver Diseases, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA.
Gao B; Laboratory for Liver Diseases, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA.
Young NS; Hematology Branch, National Heart, Lung, and Blood Institute, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA.
Calado RT; Department of Internal Medicine, Ribeirão Preto School of Medicine, University of São Paulo, Ribeirão Preto, SP, Brazil.; Center for Cell-based Therapy, São Paulo Research Foundation (FAPESP), Ribeirão Preto, SP, Brazil.; Pokaż więcej
Źródło:: Liver international : official journal of the International Association for the Study of the Liver [Liver Int] 2018 Jan; Vol. 38 (1), pp. 144-154. Date of Electronic Publication: 2017 Aug 19.
Typ publikacji:: Comparative Study; Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Diet, High-Fat*
Energy Metabolism*/drug effects
Lipid Metabolism*/drug effects
Lipid Metabolism*/genetics
Telomere Shortening*
Fatty Liver/*enzymology
Hepatocytes/*enzymology
Liver/*enzymology
Telomerase/*deficiency
Animals ; Blood Glucose/metabolism ; Disease Models, Animal ; Enzyme Inhibitors/pharmacology ; Fatty Liver/blood ; Fatty Liver/genetics ; Fatty Liver/pathology ; Hepatocytes/drug effects ; Hepatocytes/pathology ; Liver/drug effects ; Liver/pathology ; Male ; Mice, Inbred C57BL ; Mice, Knockout ; RNA/genetics ; Telomerase/antagonists & inhibitors ; Telomerase/genetics ; Zidovudine/pharmacology

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