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Wyszukujesz frazę ""Toxicity Tests, Acute"" wg kryterium: Temat


Tytuł :
Acute and Subacute Toxicity and Cytotoxicity of Opuntia Dillenii (Ker-Gawl) Haw. Seed Oil and Its Impact on the Isolated Rat Diaphragm Glucose Absorption.
Autorzy :
Bouhrim M; Laboratory of Bioresources, Biotechnology, Ethnopharmacology and Health, Faculty of Sciences Mohammed First University, Oujda B.P. 717, Morocco.
Boutahiri S; Univ. Lille, University of Liège, University of Picardy Jules Verne, JUNIA, UMRT 1158 BioEcoAgro, Specialized Metabolites of Plant Origin, F-59000 Lille, France.; Research Team on the Chemistry of Bioactive Molecules and Environment, Laboratory of Innovative Materials and Biotechnology of Natural Resources, Faculty of Sciences, Moulay Ismaïl University, Meknes, Zitoune Meknes B.P. 11201, Morocco.
Kharchoufa L; Laboratory of Bioresources, Biotechnology, Ethnopharmacology and Health, Faculty of Sciences Mohammed First University, Oujda B.P. 717, Morocco.
Mechchate H; Laboratory of biotechnology, Environment, Agri-Food, and Health (LBEAS), Faculty of Sciences, Dhar El Mahraz, Sidi Mohamed Ben Abdellah University (USMBA), Fez B.P. 1796, Morocco.
Mohamed Al Kamaly O; Department of Pharmaceutical Sciences, College of Pharmacy, Princess Nourah Bint Abdulrahman University, Riyadh 11564, Saudi Arabia.
Berraaouan A; Laboratory of Bioresources, Biotechnology, Ethnopharmacology and Health, Faculty of Sciences Mohammed First University, Oujda B.P. 717, Morocco.
Eto B; Laboratories-TBC, Faculty of Pharmaceutical and Biological Sciences, B.P. 83 Lille, France.
Ziyyat A; Laboratory of Bioresources, Biotechnology, Ethnopharmacology and Health, Faculty of Sciences Mohammed First University, Oujda B.P. 717, Morocco.
Mekhfi H; Laboratory of Bioresources, Biotechnology, Ethnopharmacology and Health, Faculty of Sciences Mohammed First University, Oujda B.P. 717, Morocco.
Legssyer A; Laboratory of Bioresources, Biotechnology, Ethnopharmacology and Health, Faculty of Sciences Mohammed First University, Oujda B.P. 717, Morocco.
Aziz M; Laboratory of Bioresources, Biotechnology, Ethnopharmacology and Health, Faculty of Sciences Mohammed First University, Oujda B.P. 717, Morocco.
Bnouham M; Laboratory of Bioresources, Biotechnology, Ethnopharmacology and Health, Faculty of Sciences Mohammed First University, Oujda B.P. 717, Morocco.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Apr 09; Vol. 26 (8). Date of Electronic Publication: 2021 Apr 09.
Typ publikacji :
Journal Article
MeSH Terms :
Absorption, Physiological*/drug effects
Toxicity Tests, Acute*
Diaphragm/*metabolism
Glucose/*metabolism
Opuntia/*chemistry
Plant Oils/*pharmacology
Seeds/*chemistry
Administration, Oral ; Animals ; Bilirubin/blood ; Biomarkers/blood ; Blood Glucose/metabolism ; Body Weight/drug effects ; Cell Death/drug effects ; Cell Survival/drug effects ; Diaphragm/drug effects ; Female ; Hep G2 Cells ; Humans ; Kidney/drug effects ; Kidney/metabolism ; Lipids/blood ; Liver/drug effects ; Liver/enzymology ; Male ; Plant Oils/administration & dosage ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Gender differences in acute toxicity, toxicokinetic and tissue distribution of amphotericin B liposomes in rats.
Autorzy :
Wang D; Department of Pharmacy, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei Province, 050017, China.
Zhang W; Department of Pharmacology, Hebei Medical University, Shijiazhuang, Hebei Province, 050000, China.
Ju JX; Department of Pharmacology, Hebei Medical University, Shijiazhuang, Hebei Province, 050000, China.
Wang LJ; Department of Pharmacology, Hebei Medical University, Shijiazhuang, Hebei Province, 050000, China.
Huang RY; Department of Pharmacology, Hebei Medical University, Shijiazhuang, Hebei Province, 050000, China.
Xu YF; Department of Pharmacology, Hebei Medical University, Shijiazhuang, Hebei Province, 050000, China.
Zhang HL; Department of Pharmacology, Hebei Medical University, Shijiazhuang, Hebei Province, 050000, China.
Qi JL; Department of Pharmacology, Hebei Medical University, Shijiazhuang, Hebei Province, 050000, China. Electronic address: .
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Źródło :
Toxicology letters [Toxicol Lett] 2021 Mar 01; Vol. 338, pp. 78-84. Date of Electronic Publication: 2020 Dec 09.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Toxicity Tests, Acute*
Amphotericin B/*toxicity
Antifungal Agents/*toxicity
Amphotericin B/administration & dosage ; Amphotericin B/pharmacokinetics ; Animals ; Antifungal Agents/administration & dosage ; Antifungal Agents/pharmacokinetics ; Chromatography, High Pressure Liquid ; Female ; Kidney/metabolism ; Liver/metabolism ; Male ; Rats, Sprague-Dawley ; Sex Factors ; Tandem Mass Spectrometry ; Tissue Distribution ; Toxicokinetics
Czasopismo naukowe
Tytuł :
Multistate models of developmental toxicity: Application to valproic acid-induced malformations in the zebrafish embryo.
Autorzy :
Siméon S; INERIS, METO Unit, Parc ALATA BP2, Verneuil en Halatte, France.
Beaudouin R; UMR-I 02 SEBIO, INERIS, Parc ALATA BP2, Verneuil en Halatte, France.
Brotzmann K; University of Heidelberg, Aquatic Ecology and Toxicology, Centre for Organismal Studies (COS), Im Neuenheimer Feld 504, D-69120 Heidelberg, Germany.
Braunbeck T; University of Heidelberg, Aquatic Ecology and Toxicology, Centre for Organismal Studies (COS), Im Neuenheimer Feld 504, D-69120 Heidelberg, Germany.
Bois FY; CERTARA UK Limited, Simcyp Division, Level 2-Acero, 1 Concourse Way, Sheffield, S1 2BJ, United Kingdom. Electronic address: .
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Źródło :
Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 2021 Mar 01; Vol. 414, pp. 115424. Date of Electronic Publication: 2021 Jan 30.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Models, Biological*
Toxicity Tests, Acute*
Abnormalities, Drug-Induced/*etiology
Teratogens/*toxicity
Valproic Acid/*toxicity
Abnormalities, Drug-Induced/embryology ; Animals ; Bayes Theorem ; Computer Simulation ; Dose-Response Relationship, Drug ; Embryo, Nonmammalian/abnormalities ; Embryo, Nonmammalian/drug effects ; Numerical Analysis, Computer-Assisted ; Teratogens/pharmacokinetics ; Toxicokinetics ; Valproic Acid/pharmacokinetics ; Zebrafish/embryology
Czasopismo naukowe
Tytuł :
Comparative acute toxicity of benzophenone derivatives and bisphenol analogues in the Asian clam Corbicula fluminea.
Autorzy :
Seoane M; Laboratorio de Microbiología, Facultad de Ciencias, Universidade da Coruña, Campus da Zapateira s/n, 15071 A, Coruña, Spain.
Cid Á; Laboratorio de Microbiología, Facultad de Ciencias, Universidade da Coruña, Campus da Zapateira s/n, 15071 A, Coruña, Spain.
Herrero C; Laboratorio de Microbiología, Facultad de Ciencias, Universidade da Coruña, Campus da Zapateira s/n, 15071 A, Coruña, Spain.
Esperanza M; Laboratorio de Microbiología, Facultad de Ciencias, Universidade da Coruña, Campus da Zapateira s/n, 15071 A, Coruña, Spain. .
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Źródło :
Ecotoxicology (London, England) [Ecotoxicology] 2021 Jan; Vol. 30 (1), pp. 142-153. Date of Electronic Publication: 2020 Nov 07.
Typ publikacji :
Journal Article
MeSH Terms :
Corbicula*/metabolism
Toxicity Tests, Acute*
Water Pollutants, Chemical*/analysis
Water Pollutants, Chemical*/toxicity
Benzophenones/*toxicity
Animals ; Catalase/metabolism ; Lipid Peroxidation
Czasopismo naukowe
Tytuł :
Effects of Dissolved Organic Carbon, Ultraviolet Light and their Co-Exposure on Deepwater Horizon crude oil acute toxicity to larval red drum (Sciaenops ocellatus).
Autorzy :
Bonatesta F; Department of Biological Sciences and the Advanced Environmental Research Institute, University of North Texas, Denton, Texas, USA.
Leads RR; Department of Biological Sciences and the Advanced Environmental Research Institute, University of North Texas, Denton, Texas, USA.
Price ER; Department of Biological Sciences and the Advanced Environmental Research Institute, University of North Texas, Denton, Texas, USA.
Roberts AP; Department of Biological Sciences and the Advanced Environmental Research Institute, University of North Texas, Denton, Texas, USA.
Mager EM; Department of Biological Sciences and the Advanced Environmental Research Institute, University of North Texas, Denton, Texas, USA.
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Źródło :
Environmental toxicology and chemistry [Environ Toxicol Chem] 2020 Dec; Vol. 39 (12), pp. 2509-2515. Date of Electronic Publication: 2020 Oct 26.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Toxicity Tests, Acute*
Ultraviolet Rays*
Carbon/*pharmacology
Organic Chemicals/*pharmacology
Perciformes/*physiology
Petroleum Pollution/*analysis
Animals ; Dose-Response Relationship, Radiation ; Gulf of Mexico ; Larva/drug effects ; Larva/radiation effects ; Petroleum/toxicity ; Polycyclic Aromatic Hydrocarbons/toxicity ; Water/chemistry ; Water Pollutants, Chemical/toxicity
Czasopismo naukowe
Tytuł :
Theoretical investigation on the contribution of HO, SO 4 radicals to the degradation of phenacetin in water: Mechanisms, kinetics, and toxicity evaluation.
Autorzy :
Li M; Environment Research Institute, Shandong University, Qingdao, 266237, PR China.
Sun J; Environment Research Institute, Shandong University, Qingdao, 266237, PR China.
Han D; School of Chemistry and Chemical Engineering, Heze University, Heze, 274015, PR China.
Wei B; Environment Research Institute, Shandong University, Qingdao, 266237, PR China.
Mei Q; Environment Research Institute, Shandong University, Qingdao, 266237, PR China.
An Z; Environment Research Institute, Shandong University, Qingdao, 266237, PR China.
Wang X; Environment Research Institute, Shandong University, Qingdao, 266237, PR China.
Cao H; Institute of Materials for Energy and Environment, School of Materials Science and Engineering, Qingdao University, Qingdao, 266071, PR China.
Xie J; School of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou, 225002, PR China.
He M; Environment Research Institute, Shandong University, Qingdao, 266237, PR China. Electronic address: .
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Źródło :
Ecotoxicology and environmental safety [Ecotoxicol Environ Saf] 2020 Nov; Vol. 204, pp. 110977. Date of Electronic Publication: 2020 Jul 30.
Typ publikacji :
Journal Article
MeSH Terms :
Toxicity Tests, Acute*
Toxicity Tests, Chronic*
Carbonates/*toxicity
Hydrogen Peroxide/*toxicity
Phenacetin/*toxicity
Sulfates/*toxicity
Animals ; Carbonates/chemistry ; Chlorophyta/drug effects ; Daphnia/drug effects ; Fishes ; Hydrogen Peroxide/chemistry ; Ions/chemistry ; Ions/toxicity ; Kinetics ; Models, Chemical ; Oxygen/chemistry ; Phenacetin/chemistry ; Sulfates/chemistry ; Water/chemistry
Czasopismo naukowe
Tytuł :
Phytochemical Identification, Acute, and Sub-Acute Oral Toxicity Studies of the Foliar Extract of Withania frutescens .
Autorzy :
El Moussaoui A; Laboratory of Biotechnology, Environment, Agrifood and Health, Faculty of Science, University of Sidi Mohamed Ben Abdellah, Fez BP.1796, Morocco.
Bourhia M; Laboratory of Chemistry-Biochemistry, Environment, Nutrition, and Health, Faculty of Medicine and Pharmacy, University of Casablanca, Casablanca BP.5696, Morocco.
Jawhari FZ; Laboratory of Biotechnology, Environment, Agrifood and Health, Faculty of Science, University of Sidi Mohamed Ben Abdellah, Fez BP.1796, Morocco.
Mechchate H; Laboratory of Biotechnology, Environment, Agrifood and Health, Faculty of Science, University of Sidi Mohamed Ben Abdellah, Fez BP.1796, Morocco.
Slighoua M; Laboratory of Biotechnology, Environment, Agrifood and Health, Faculty of Science, University of Sidi Mohamed Ben Abdellah, Fez BP.1796, Morocco.
Bari A; Department of Pharmaceutical Chemistry and Central Laboratory, College of Pharmacy King Saud University, Riyadh 11451, Saudi Arabia.
Ullah R; Department of Pharmacognosy (MAPPRC), College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Mahmood HM; Department of Pharmacology, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Ali SS; Department of Pharmaceutical Chemistry and Central Laboratory, College of Pharmacy King Saud University, Riyadh 11451, Saudi Arabia.
Ibenmoussa S; Laboratory of Chemistry-Biochemistry, Environment, Nutrition, and Health, Faculty of Medicine and Pharmacy, University of Casablanca, Casablanca BP.5696, Morocco.
Bousta D; Laboratory of Biotechnology, Environment, Agrifood and Health, Faculty of Science, University of Sidi Mohamed Ben Abdellah, Fez BP.1796, Morocco.
Bari A; Laboratory of Biotechnology, Environment, Agrifood and Health, Faculty of Science, University of Sidi Mohamed Ben Abdellah, Fez BP.1796, Morocco.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2020 Oct 02; Vol. 25 (19). Date of Electronic Publication: 2020 Oct 02.
Typ publikacji :
Journal Article
MeSH Terms :
Toxicity Tests, Acute*
Phytochemicals/*analysis
Phytochemicals/*toxicity
Plant Extracts/*chemistry
Plant Extracts/*toxicity
Plant Leaves/*chemistry
Withania/*chemistry
Animals ; Body Weight/drug effects ; Gas Chromatography-Mass Spectrometry ; Mice ; Organ Size/drug effects
Czasopismo naukowe
Tytuł :
Modelling quantitative structure activity-activity relationships (QSAARs): auto-pass-pass, a new approach to fill data gaps in environmental risk assessment under the REACH regulation.
Autorzy :
Bouhedjar K; Laboratoire de Synthèse et Biocatalyse Organique, Département de Chimie, Faculté des Sciences, Université Badji Mokhtar Annaba , Annaba, Algeria.; Laboratoire Bioinformatique, Centre de Recherche en Biotechnologie (CRBt) , Constantine, Algeria.; Laboratory of Environmental Chemistry and Toxicology, Istituto Di Ricerche Farmacologiche Mario Negri IRCCS , Milano, Italy.
Benfenati E; Laboratory of Environmental Chemistry and Toxicology, Istituto Di Ricerche Farmacologiche Mario Negri IRCCS , Milano, Italy.
Nacereddine AK; Laboratory of Physical Chemistry and Biology of Materials, Department of Physics and Chemistry, Higher Normal School of Technological Education-Skikda , Skikda, Algeria.
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Źródło :
SAR and QSAR in environmental research [SAR QSAR Environ Res] 2020 Oct; Vol. 31 (10), pp. 785-801. Date of Electronic Publication: 2020 Sep 03.
Typ publikacji :
Journal Article
MeSH Terms :
Quantitative Structure-Activity Relationship*
Toxicity Tests, Acute*
Aquatic Organisms/*drug effects
Water Pollutants, Chemical/*toxicity
Aliivibrio fischeri/drug effects ; Animals ; Daphnia/drug effects ; Fishes ; Government Regulation ; Microalgae/drug effects ; Models, Chemical ; Risk Assessment ; Tetrahymena pyriformis/drug effects
Czasopismo naukowe
Tytuł :
Application of a behavioural and biochemical endpoint in ecotoxicity testing with Exaiptasia pallida.
Autorzy :
Ianna ML; Marine Ecology Research Centre, School of Environment, Science and Engineering, Southern Cross University, Military Road, East Lismore, NSW, 2480, Australia; School of Environment, Science and Engineering, Southern Cross University, Military Road, East Lismore, NSW, 2480, Australia.
Reichelt-Brushett A; Marine Ecology Research Centre, School of Environment, Science and Engineering, Southern Cross University, Military Road, East Lismore, NSW, 2480, Australia; School of Environment, Science and Engineering, Southern Cross University, Military Road, East Lismore, NSW, 2480, Australia. Electronic address: .
Howe PL; Marine Ecology Research Centre, School of Environment, Science and Engineering, Southern Cross University, Military Road, East Lismore, NSW, 2480, Australia; School of Environment, Science and Engineering, Southern Cross University, Military Road, East Lismore, NSW, 2480, Australia.
Brushett D; School of Environment, Science and Engineering, Southern Cross University, Military Road, East Lismore, NSW, 2480, Australia.
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Źródło :
Chemosphere [Chemosphere] 2020 Oct; Vol. 257, pp. 127240. Date of Electronic Publication: 2020 Jun 01.
Typ publikacji :
Journal Article
MeSH Terms :
Toxicity Tests, Acute*
Sea Anemones/*physiology
Water Pollutants, Chemical/*toxicity
Animals ; Copper/toxicity ; Sea Anemones/growth & development
Czasopismo naukowe
Tytuł :
Key Opportunities to Replace, Reduce, and Refine Regulatory Fish Acute Toxicity Tests.
Autorzy :
Burden N; NC3Rs, London, United Kingdom.
Benstead R; Fera Science, Sand Hutton, York, United Kingdom.
Benyon K; Syngenta, Product Safety, Bracknell, Berkshire, United Kingdom.
Clook M; Chemicals Regulation Division, Health and Safety Executive, York, United Kingdom.
Green C; Department for Environment, Food and Rural Affairs, London, United Kingdom.
Handley J; Charnwood Molecular, Nottingham, United Kingdom.
Harper N; Chemicals Regulation Division, Health and Safety Executive, Bootle, Merseyside, United Kingdom.
Maynard SK; AstraZeneca, Eastbrook House, Cambridge, United Kingdom.
Mead C; Batelle, Chelmsford, Essex, United Kingdom.
Pearson A; Environment Agency, Wallingford, Oxfordshire, United Kingdom.
Ryder K; Home Office, Dundee, United Kingdom.
Sheahan D; Cefas Fisheries Laboratory, Lowestoft, Suffolk, United Kingdom.
van Egmond R; Unilever, Safety & Environmental Assurance Centre, Sharnbrook, Bedford, United Kingdom.
Wheeler JR; Shell Health, Shell International, The Hague, The Netherlands.
Hutchinson TH; University of Plymouth, Plymouth, Devon, United Kingdom.
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Źródło :
Environmental toxicology and chemistry [Environ Toxicol Chem] 2020 Oct; Vol. 39 (10), pp. 2076-2089. Date of Electronic Publication: 2020 Aug 24.
Typ publikacji :
Journal Article
MeSH Terms :
Fishes*
Animal Testing Alternatives/*methods
Ecotoxicology/*methods
Hazardous Substances/*toxicity
Toxicity Tests, Acute/*methods
Animal Testing Alternatives/legislation & jurisprudence ; Animals ; Ecotoxicology/legislation & jurisprudence ; Lethal Dose 50 ; Organisation for Economic Co-Operation and Development ; Risk Assessment ; Toxicity Tests, Acute/standards
Czasopismo naukowe
Tytuł :
Withania frutescens. L Extract: Phytochemical Characterization and Acute and Repeated Dose 28-Day Oral Toxicity Studies in Mice.
Autorzy :
Moussaoui AE; Laboratory of Biotechnology, Environment, Agrifood and Health, Faculty of Sciences, University of Sidi Mohamed Ben Abdellah, Fez, Morocco.
Bourhia M; Laboratory of Chemistry-Biochemistry, Environment, Nutrition, and Health, Faculty of Medicine and Pharmacy, University of Casablanca, B.P 5696 Casablanca, Morocco.
Jawhari FZ; Laboratory of Biotechnology, Environment, Agrifood and Health, Faculty of Sciences, University of Sidi Mohamed Ben Abdellah, Fez, Morocco.
Es-Safi I; Laboratory of Biotechnology, Environment, Agrifood and Health, Faculty of Sciences, University of Sidi Mohamed Ben Abdellah, Fez, Morocco.
Ali SS; Department of Pharmaceutical Chemistry and Central Laboratory, College of Pharmacy King Saud University, Riyadh, Saudi Arabia.
Bari A; Department of Pharmaceutical Chemistry and Central Laboratory, College of Pharmacy King Saud University, Riyadh, Saudi Arabia.
Mahmood HM; Department of Pharmacology, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Bousta D; Laboratory of Biotechnology, Environment, Agrifood and Health, Faculty of Sciences, University of Sidi Mohamed Ben Abdellah, Fez, Morocco.
Bari A; Laboratory of Biotechnology, Environment, Agrifood and Health, Faculty of Sciences, University of Sidi Mohamed Ben Abdellah, Fez, Morocco.
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Źródło :
BioMed research international [Biomed Res Int] 2020 Sep 26; Vol. 2020, pp. 1976298. Date of Electronic Publication: 2020 Sep 26 (Print Publication: 2020).
Typ publikacji :
Journal Article
MeSH Terms :
Toxicity Tests, Acute*
Phytochemicals/*analysis
Plant Extracts/*administration & dosage
Plant Extracts/*toxicity
Withania/*chemistry
Administration, Oral ; Animals ; Body Weight/drug effects ; Gas Chromatography-Mass Spectrometry ; Mice ; Organ Size/drug effects ; Organ Specificity/drug effects ; Plant Roots/chemistry
Czasopismo naukowe
Tytuł :
Consensus QSAR models estimating acute toxicity to aquatic organisms from different trophic levels: algae, Daphnia and fish.
Autorzy :
Lunghini F; Laboratory of Chemoinformatics, University of Strasbourg , Strasbourg, France.; Toxicological and Environmental Risk Assessment Unit , Solvay S.A., St. Fons, France.
Marcou G; Laboratory of Chemoinformatics, University of Strasbourg , Strasbourg, France.
Azam P; Toxicological and Environmental Risk Assessment Unit , Solvay S.A., St. Fons, France.
Enrici MH; Toxicological and Environmental Risk Assessment Unit , Solvay S.A., St. Fons, France.
Van Miert E; Toxicological and Environmental Risk Assessment Unit , Solvay S.A., St. Fons, France.
Varnek A; Laboratory of Chemoinformatics, University of Strasbourg , Strasbourg, France.
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Źródło :
SAR and QSAR in environmental research [SAR QSAR Environ Res] 2020 Sep; Vol. 31 (9), pp. 655-675. Date of Electronic Publication: 2020 Aug 17.
Typ publikacji :
Journal Article
MeSH Terms :
Fishes*
Quantitative Structure-Activity Relationship*
Toxicity Tests, Acute*
Daphnia/*drug effects
Microalgae/*drug effects
Water Pollutants, Chemical/*toxicity
Animals ; Support Vector Machine
Czasopismo naukowe
Tytuł :
Multiple Linear Regression Modeling Predicts the Effects of Surface Water Chemistry on Acute Vanadium Toxicity to Model Freshwater Organisms.
Autorzy :
Gillio Meina E; Toxicology Centre, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Niyogi S; Toxicology Centre, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.; Department of Biology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Liber K; Toxicology Centre, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
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Źródło :
Environmental toxicology and chemistry [Environ Toxicol Chem] 2020 Sep; Vol. 39 (9), pp. 1737-1745. Date of Electronic Publication: 2020 Aug 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Toxicity Tests, Acute*
Fresh Water/*chemistry
Vanadium/*toxicity
Animals ; Aquatic Organisms/drug effects ; Daphnia/drug effects ; Environmental Exposure/analysis ; Hydrogen-Ion Concentration ; Lethal Dose 50 ; Linear Models ; Oncorhynchus mykiss/physiology ; Reproducibility of Results ; Water Pollutants, Chemical/toxicity ; Water Quality/standards
Czasopismo naukowe
Tytuł :
Effect of the structural factors of organic compounds on the acute toxicity toward Daphnia magna .
Autorzy :
Tinkov OV; Department of Computer Science, Military Institute of the Ministry of Defense , Tiraspol, Moldova.
Grigorev VY; Department of Computer-aided Molecular Design, Institute of Physiologically Active Compounds of the Russian Academy of Science , Chernogolovka, Russia.
Razdolsky AN; Department of Computer-aided Molecular Design, Institute of Physiologically Active Compounds of the Russian Academy of Science , Chernogolovka, Russia.
Grigoryeva LD; Department of Fundamental Physicochemical Engineering, Moscow State University , Moscow, Russia.
Dearden JC; School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University , Liverpool, UK.
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Źródło :
SAR and QSAR in environmental research [SAR QSAR Environ Res] 2020 Aug; Vol. 31 (8), pp. 615-641. Date of Electronic Publication: 2020 Jul 27.
Typ publikacji :
Journal Article
MeSH Terms :
Quantitative Structure-Activity Relationship*
Toxicity Tests, Acute*
Daphnia/*drug effects
Organic Chemicals/*toxicity
Water Pollutants, Chemical/*toxicity
Animals ; Molecular Structure ; Support Vector Machine
Czasopismo naukowe
Tytuł :
β-Phenylethylamine and various monomethylated and para-halogenated analogs. Acute toxicity studies in mice.
Autorzy :
Mosnaim AD; Department of Cellular and Molecular Pharmacology, The Chicago Medical School at Rosalind Franklin University of Medicine and Science, N. Chicago, IL, USA.
Wolf ME; International Neuropsychiatry Consultants, Highland Park, IL, USA.
Iii O'Donnell JJ; Department of Cellular and Molecular Pharmacology, The Chicago Medical School at Rosalind Franklin University of Medicine and Science, N. Chicago, IL, USA.
Hudzik T; Safety Pharmacology, Collegeville, PA, USA.
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Źródło :
Drug and chemical toxicology [Drug Chem Toxicol] 2020 Jul; Vol. 43 (4), pp. 369-372. Date of Electronic Publication: 2019 Jan 07.
Typ publikacji :
Journal Article
MeSH Terms :
Toxicity Tests, Acute*
Phenethylamines/*toxicity
Animals ; Lethal Dose 50 ; Male ; Mice
Czasopismo naukowe
Tytuł :
Acute toxicity "six-pack" studies supporting approved new drug applications in the U.S., 2015-2018.
Autorzy :
Manuppello J; Physicians Committee for Responsible Medicine, 5100 Wisconsin Ave., NW, Suite 400, Washington, DC, 20016-4131, USA. Electronic address: .
Sullivan K; Physicians Committee for Responsible Medicine, 5100 Wisconsin Ave., NW, Suite 400, Washington, DC, 20016-4131, USA.
Baker E; Physicians Committee for Responsible Medicine, 5100 Wisconsin Ave., NW, Suite 400, Washington, DC, 20016-4131, USA.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2020 Jul; Vol. 114, pp. 104666. Date of Electronic Publication: 2020 Apr 23.
Typ publikacji :
Journal Article
MeSH Terms :
Animal Testing Alternatives*
Toxicity Tests, Acute*
Pharmaceutical Preparations/*analysis
Animals ; Humans ; United States ; United States Food and Drug Administration
Czasopismo naukowe
Tytuł :
Antiulcer potential and molecular docking of flavonoids from Ocimum forskolei Benth., family Lamiaceae .
Autorzy :
Zahran EM; Department of Pharmacognosy, Faculty of Pharmacy, Deraya University, Universities Zone, New Minia City, Egypt.
Abdelmohsen UR; Department of Pharmacognosy, Faculty of Pharmacy, Minia University, Minia, Egypt.
Hussein AS; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, October University for Modern Sciences and Arts (MSA), Giza, Egypt.
Salem MA; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, October University for Modern Sciences and Arts (MSA), Giza, Egypt.
Khalil HE; Department of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa, Saudi Arabia.
Yehia Desoukey S; Department of Pharmacognosy, Faculty of Pharmacy, Minia University, Minia, Egypt.
Fouad MA; Department of Pharmacognosy, Faculty of Pharmacy, Minia University, Minia, Egypt.
Kamel MS; Department of Pharmacognosy, Faculty of Pharmacy, Deraya University, Universities Zone, New Minia City, Egypt.; Department of Pharmacognosy, Faculty of Pharmacy, Minia University, Minia, Egypt.
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Źródło :
Natural product research [Nat Prod Res] 2021 Jun; Vol. 35 (11), pp. 1933-1937. Date of Electronic Publication: 2019 Jul 30.
Typ publikacji :
Journal Article
MeSH Terms :
Molecular Docking Simulation*
Anti-Ulcer Agents/*therapeutic use
Flavonoids/*chemistry
Flavonoids/*therapeutic use
Ocimum/*chemistry
Acetates/chemistry ; Anti-Ulcer Agents/pharmacology ; Catalytic Domain ; Ethanol/chemistry ; Flavonoids/pharmacology ; Molecular Dynamics Simulation ; Phytochemicals/chemistry ; Phytochemicals/therapeutic use ; Plant Extracts/chemistry ; Solvents ; Toxicity Tests, Acute ; Ulcer/drug therapy ; Ulcer/pathology
Czasopismo naukowe
Tytuł :
Bioassay-guided fractionation and identification of antidiabetic compounds from the rind of Punica Granatum Var. nana.
Autorzy :
El Deeb KS; Department of Pharmacognosy, Faculty of Pharmacy, Cairo University, Cairo, Egypt.
Eid HH; Department of Pharmacognosy, Faculty of Pharmacy, Cairo University, Cairo, Egypt.
Ali ZY; Department of Biochemistry, National Organization for Drug Control & Research (NODCAR), Giza, Egypt.
Shams MM; Department of Medicinal plants and natural products, National Organization for Drug Control & Research (NODCAR), Giza, Egypt.
Elfiky AM; Department of Medicinal plants and natural products, National Organization for Drug Control & Research (NODCAR), Giza, Egypt.
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Źródło :
Natural product research [Nat Prod Res] 2021 Jun; Vol. 35 (12), pp. 2103-2106. Date of Electronic Publication: 2019 Aug 22.
Typ publikacji :
Journal Article
MeSH Terms :
Diabetes Mellitus, Experimental/*drug therapy
Hypoglycemic Agents/*chemistry
Hypoglycemic Agents/*pharmacology
Plant Extracts/*pharmacology
Pomegranate/*chemistry
Animals ; Anti-Inflammatory Agents, Non-Steroidal/chemistry ; Anti-Inflammatory Agents, Non-Steroidal/pharmacology ; Antioxidants/analysis ; Antioxidants/chemistry ; Antioxidants/pharmacology ; Chemical Fractionation ; Diabetes Mellitus, Experimental/metabolism ; Dose-Response Relationship, Drug ; Gallic Acid/isolation & purification ; Hypoglycemic Agents/administration & dosage ; Oxidative Stress/drug effects ; Plant Extracts/administration & dosage ; Plant Extracts/chemistry ; Rats ; Rutin/isolation & purification ; Toxicity Tests, Acute
Czasopismo naukowe
Tytuł :
Acute and chronic toxicity tests of systemic insecticides, four neonicotinoids and fipronil, using the tadpoles of the western clawed frog Silurana tropicalis.
Autorzy :
Saka M; Division of Aquatic Environment, Kyoto Prefectural Institute of Public Health and Environment, Murakamicho 395, Fushimi-ku, Kyoto, 612-8369, Japan. Electronic address: .
Tada N; Division of Aquatic Environment, Kyoto Prefectural Institute of Public Health and Environment, Murakamicho 395, Fushimi-ku, Kyoto, 612-8369, Japan. Electronic address: .
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Źródło :
Chemosphere [Chemosphere] 2021 May; Vol. 270, pp. 129418. Date of Electronic Publication: 2020 Dec 26.
Typ publikacji :
Journal Article
MeSH Terms :
Insecticides*/toxicity
Water Pollutants, Chemical*/toxicity
Animals ; Larva ; Neonicotinoids/toxicity ; Nitro Compounds ; Pyrazoles ; Toxicity Tests, Acute ; Toxicity Tests, Chronic
Czasopismo naukowe
Tytuł :
Green toxicological investigation for biofuel candidates.
Autorzy :
Heger S; Department of Ecosystem Analysis, Institute for Environmental Research, RWTH Aachen University, Worringerweg 1, 52074 Aachen, Germany.
Brendt J; Department of Ecosystem Analysis, Institute for Environmental Research, RWTH Aachen University, Worringerweg 1, 52074 Aachen, Germany.
Hollert H; Department of Evolutionary Ecology and Environmental Toxicology, Goethe University Frankfurt, Max-von-Laue-Str. 13, 60438 Frankfurt am Main, Germany.
Roß-Nickoll M; Department of Ecosystem Analysis, Institute for Environmental Research, RWTH Aachen University, Worringerweg 1, 52074 Aachen, Germany.
Du M; Department of Ecosystem Analysis, Institute for Environmental Research, RWTH Aachen University, Worringerweg 1, 52074 Aachen, Germany. Electronic address: .
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Źródło :
The Science of the total environment [Sci Total Environ] 2021 Apr 10; Vol. 764, pp. 142902. Date of Electronic Publication: 2020 Oct 13.
Typ publikacji :
Journal Article
MeSH Terms :
Biofuels*/toxicity
Water Pollutants, Chemical*
Animals ; Cell Line ; Cricetinae ; Daphnia ; Humans ; Toxicity Tests, Acute ; Zebrafish
Czasopismo naukowe

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