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Wyszukujesz frazę ""Toxicity Tests, Acute"" wg kryterium: Temat


Tytuł:
The toxicity assessment of neorudin in cynomolgus monkeys.
Autorzy:
Liu YB; Beijing Institute of Radiation Medicine, China.
Ren BY; Beijing Institute of Radiation Medicine, China.
Zhou XC; Beijing Institute of Radiation Medicine, China.
Zhang L; Beijing Institute of Radiation Medicine, China.
Liu Y; Beijing Institute of Radiation Medicine, China.
Zheng C; Beijing Institute of Radiation Medicine, China.
Wei JF; Beijing Union Jianhao Medical Technology Development Co., LTD., China.
Wu CT; Beijing Institute of Radiation Medicine, China.
Jin JD; Beijing Institute of Radiation Medicine, China.
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Źródło:
The Journal of toxicological sciences [J Toxicol Sci] 2023; Vol. 48 (4), pp. 179-189.
Typ publikacji:
Journal Article
MeSH Terms:
Cardiovascular System*/drug effects
Hirudins*/administration & dosage
Hirudins*/toxicity
Respiratory System*/drug effects
Toxicity Tests, Acute*
Animals ; Dose-Response Relationship, Drug ; Infusions, Intravenous ; Injections, Intravenous ; Macaca fascicularis ; Saline Solution/administration & dosage
Czasopismo naukowe
Tytuł:
Evaluation of the acute and 28-day sub-acute intravenous toxicity of α-l-guluronic acid (ALG; G2013) in mice.
Autorzy:
Mahdian-Shakib A; Applied Virology Research Centre, Baqiyatallah University of Medical Sciences, Tehran, Iran.
Hashemzadeh MS; Applied Virology Research Centre, Baqiyatallah University of Medical Sciences, Tehran, Iran.
Anissian A; Veterinary Pathology Department, Islamic Azad University, Abhar, Iran.
Oraei M; Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Mirshafiey A; Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
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Źródło:
Drug and chemical toxicology [Drug Chem Toxicol] 2022 Jan; Vol. 45 (1), pp. 151-160. Date of Electronic Publication: 2019 Sep 19.
Typ publikacji:
Journal Article
MeSH Terms:
Toxicity Tests, Acute*
Animals ; Female ; Hexuronic Acids ; Lethal Dose 50 ; Male ; Mice ; Mice, Inbred BALB C
Czasopismo naukowe
Tytuł:
Evaluation of Acute and Subchronic Toxicity Induced by the Crude Ethanol Extract of Plukenetia volubilis Linneo Leaves in Swiss Albino Mice.
Autorzy:
Tran PT; Institute of Biotechnology and Food Technology, Industrial University of Ho Chi Minh City, 12 Nguyen Van Bao street, Go Vap District, Ho Chi Minh City, Vietnam.
Tran TTN; Faculty of Chemical Engineering, Industrial University of Ho Chi Minh City, 12 Nguyen Van Bao street, Go Vap District, Ho Chi Minh City, Vietnam.
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Źródło:
BioMed research international [Biomed Res Int] 2021 Oct 19; Vol. 2021, pp. 6524658. Date of Electronic Publication: 2021 Oct 19 (Print Publication: 2021).
Typ publikacji:
Evaluation Study; Journal Article
MeSH Terms:
Toxicity Tests, Acute*
Toxicity Tests, Subchronic*
Complex Mixtures/*toxicity
Ethanol/*chemistry
Euphorbiaceae/*chemistry
Plant Extracts/*toxicity
Plant Leaves/*chemistry
Animals ; Behavior, Animal/drug effects ; Body Weight/drug effects ; Drinking Behavior/drug effects ; Feeding Behavior/drug effects ; Male ; Mice ; Organ Size/drug effects ; Phytochemicals/analysis ; Urinalysis
Czasopismo naukowe
Tytuł:
A genome-wide portrait of pervasive drug contaminants.
Autorzy:
Ogbede JU; Genome Science & Technology Graduate Program, University of British Columbia, Vancouver, Canada.
Giaever G; Faculty of Pharmaceutical Science, University of British Columbia, Vancouver, Canada.
Nislow C; Genome Science & Technology Graduate Program, University of British Columbia, Vancouver, Canada. .; Faculty of Pharmaceutical Science, University of British Columbia, Vancouver, Canada. .
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Źródło:
Scientific reports [Sci Rep] 2021 Jun 14; Vol. 11 (1), pp. 12487. Date of Electronic Publication: 2021 Jun 14.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Drug Contamination*
Toxicity Tests, Acute*
Nitrosamines/*toxicity
Saccharomyces cerevisiae/*drug effects
Arginine/biosynthesis ; Biosynthetic Pathways/drug effects ; Biosynthetic Pathways/genetics ; DNA Damage/drug effects ; DNA Repair/drug effects ; DNA, Fungal/drug effects ; DNA, Fungal/isolation & purification ; Genetic Fitness/drug effects ; Genome, Fungal/drug effects ; Mitochondria/drug effects ; Mitochondria/metabolism ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae/growth & development ; Saccharomyces cerevisiae/metabolism ; Sequence Deletion
Czasopismo naukowe
Tytuł:
Acute and Subacute Toxicity and Cytotoxicity of Opuntia Dillenii (Ker-Gawl) Haw. Seed Oil and Its Impact on the Isolated Rat Diaphragm Glucose Absorption.
Autorzy:
Bouhrim M; Laboratory of Bioresources, Biotechnology, Ethnopharmacology and Health, Faculty of Sciences Mohammed First University, Oujda B.P. 717, Morocco.
Boutahiri S; Univ. Lille, University of Liège, University of Picardy Jules Verne, JUNIA, UMRT 1158 BioEcoAgro, Specialized Metabolites of Plant Origin, F-59000 Lille, France.; Research Team on the Chemistry of Bioactive Molecules and Environment, Laboratory of Innovative Materials and Biotechnology of Natural Resources, Faculty of Sciences, Moulay Ismaïl University, Meknes, Zitoune Meknes B.P. 11201, Morocco.
Kharchoufa L; Laboratory of Bioresources, Biotechnology, Ethnopharmacology and Health, Faculty of Sciences Mohammed First University, Oujda B.P. 717, Morocco.
Mechchate H; Laboratory of biotechnology, Environment, Agri-Food, and Health (LBEAS), Faculty of Sciences, Dhar El Mahraz, Sidi Mohamed Ben Abdellah University (USMBA), Fez B.P. 1796, Morocco.
Mohamed Al Kamaly O; Department of Pharmaceutical Sciences, College of Pharmacy, Princess Nourah Bint Abdulrahman University, Riyadh 11564, Saudi Arabia.
Berraaouan A; Laboratory of Bioresources, Biotechnology, Ethnopharmacology and Health, Faculty of Sciences Mohammed First University, Oujda B.P. 717, Morocco.
Eto B; Laboratories-TBC, Faculty of Pharmaceutical and Biological Sciences, B.P. 83 Lille, France.
Ziyyat A; Laboratory of Bioresources, Biotechnology, Ethnopharmacology and Health, Faculty of Sciences Mohammed First University, Oujda B.P. 717, Morocco.
Mekhfi H; Laboratory of Bioresources, Biotechnology, Ethnopharmacology and Health, Faculty of Sciences Mohammed First University, Oujda B.P. 717, Morocco.
Legssyer A; Laboratory of Bioresources, Biotechnology, Ethnopharmacology and Health, Faculty of Sciences Mohammed First University, Oujda B.P. 717, Morocco.
Aziz M; Laboratory of Bioresources, Biotechnology, Ethnopharmacology and Health, Faculty of Sciences Mohammed First University, Oujda B.P. 717, Morocco.
Bnouham M; Laboratory of Bioresources, Biotechnology, Ethnopharmacology and Health, Faculty of Sciences Mohammed First University, Oujda B.P. 717, Morocco.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2021 Apr 09; Vol. 26 (8). Date of Electronic Publication: 2021 Apr 09.
Typ publikacji:
Journal Article
MeSH Terms:
Absorption, Physiological*/drug effects
Toxicity Tests, Acute*
Diaphragm/*metabolism
Glucose/*metabolism
Opuntia/*chemistry
Plant Oils/*pharmacology
Seeds/*chemistry
Administration, Oral ; Animals ; Bilirubin/blood ; Biomarkers/blood ; Blood Glucose/metabolism ; Body Weight/drug effects ; Cell Death/drug effects ; Cell Survival/drug effects ; Diaphragm/drug effects ; Female ; Hep G2 Cells ; Humans ; Kidney/drug effects ; Kidney/metabolism ; Lipids/blood ; Liver/drug effects ; Liver/enzymology ; Male ; Plant Oils/administration & dosage ; Rats, Wistar
Czasopismo naukowe
Tytuł:
Safety evaluation of Aloe vera soft capsule in acute, subacute toxicity and genotoxicity study.
Autorzy:
Wu J; Institute of Toxicology and Risk Assessment, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing, Jiangsu, China.
Zhang Y; Institute of Toxicology and Risk Assessment, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing, Jiangsu, China.
Lv Z; Institute of Toxicology and Risk Assessment, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing, Jiangsu, China.
Yu P; Institute of Toxicology and Risk Assessment, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing, Jiangsu, China.
Shi W; Institute of Toxicology and Risk Assessment, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing, Jiangsu, China.
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Źródło:
PloS one [PLoS One] 2021 Mar 26; Vol. 16 (3), pp. e0249356. Date of Electronic Publication: 2021 Mar 26 (Print Publication: 2021).
Typ publikacji:
Journal Article
MeSH Terms:
Mutagenicity Tests*
Safety*
Toxicity Tests, Acute*
Aloe/*toxicity
Animals ; Capsules ; DNA Damage ; Mice ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł:
Acute and sub-acute toxicity evaluation of the root extract of Rheum turkestanicum Janisch.
Autorzy:
Jahani Yazdi A; Department of Laboratory Sciences, School of Paramedical Sciences, Mashhad University of Medical Sciences, Mashhad, Iran.
Javanshir S; Student Research Committee, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran.
Soukhtanloo M; Faculty of Medicine, Department of Clinical Biochemistry, Mashhad University of Medical Sciences, Mashhad, Iran.
Jalili-Nik M; Student Research Committee, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran.
Jafarian AH; Cancer Molecular Pathology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Iranshahi M; Biotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran.
Hasanpour M; Biotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran.
Khatami SM; Faculty of Samen Hojaj, Department of Chemistry, Mashhad Branch Technical and Vocational University (TVU), Tehran, Iran.
Hosseini A; Pharmacological Research Center of Medicinal Plants, Mashhad University of Medical Sciences, Mashhad, Iran.
Amiri MS; Department of Biology, Payame Noor University, Tehran, Iran.
Ghorbani A; Pharmacological Research Center of Medicinal Plants, Mashhad University of Medical Sciences, Mashhad, Iran.
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Źródło:
Drug and chemical toxicology [Drug Chem Toxicol] 2020 Nov; Vol. 43 (6), pp. 609-615. Date of Electronic Publication: 2019 Jul 02.
Typ publikacji:
Journal Article
MeSH Terms:
Toxicity Tests, Acute*
Toxicity Tests, Subacute*
Plant Extracts/*toxicity
Plant Roots/*toxicity
Rheum/*toxicity
Administration, Oral ; Animals ; Biomarkers/blood ; Female ; Lethal Dose 50 ; Male ; Mice ; No-Observed-Adverse-Effect Level ; Plant Extracts/administration & dosage ; Rats, Wistar ; Risk Assessment ; Time Factors
Czasopismo naukowe
Tytuł:
Phytochemical Identification, Acute, and Sub-Acute Oral Toxicity Studies of the Foliar Extract of Withania frutescens .
Autorzy:
El Moussaoui A; Laboratory of Biotechnology, Environment, Agrifood and Health, Faculty of Science, University of Sidi Mohamed Ben Abdellah, Fez BP.1796, Morocco.
Bourhia M; Laboratory of Chemistry-Biochemistry, Environment, Nutrition, and Health, Faculty of Medicine and Pharmacy, University of Casablanca, Casablanca BP.5696, Morocco.
Jawhari FZ; Laboratory of Biotechnology, Environment, Agrifood and Health, Faculty of Science, University of Sidi Mohamed Ben Abdellah, Fez BP.1796, Morocco.
Mechchate H; Laboratory of Biotechnology, Environment, Agrifood and Health, Faculty of Science, University of Sidi Mohamed Ben Abdellah, Fez BP.1796, Morocco.
Slighoua M; Laboratory of Biotechnology, Environment, Agrifood and Health, Faculty of Science, University of Sidi Mohamed Ben Abdellah, Fez BP.1796, Morocco.
Bari A; Department of Pharmaceutical Chemistry and Central Laboratory, College of Pharmacy King Saud University, Riyadh 11451, Saudi Arabia.
Ullah R; Department of Pharmacognosy (MAPPRC), College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Mahmood HM; Department of Pharmacology, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Ali SS; Department of Pharmaceutical Chemistry and Central Laboratory, College of Pharmacy King Saud University, Riyadh 11451, Saudi Arabia.
Ibenmoussa S; Laboratory of Chemistry-Biochemistry, Environment, Nutrition, and Health, Faculty of Medicine and Pharmacy, University of Casablanca, Casablanca BP.5696, Morocco.
Bousta D; Laboratory of Biotechnology, Environment, Agrifood and Health, Faculty of Science, University of Sidi Mohamed Ben Abdellah, Fez BP.1796, Morocco.
Bari A; Laboratory of Biotechnology, Environment, Agrifood and Health, Faculty of Science, University of Sidi Mohamed Ben Abdellah, Fez BP.1796, Morocco.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2020 Oct 02; Vol. 25 (19). Date of Electronic Publication: 2020 Oct 02.
Typ publikacji:
Journal Article
MeSH Terms:
Toxicity Tests, Acute*
Phytochemicals/*analysis
Phytochemicals/*toxicity
Plant Extracts/*chemistry
Plant Extracts/*toxicity
Plant Leaves/*chemistry
Withania/*chemistry
Animals ; Body Weight/drug effects ; Gas Chromatography-Mass Spectrometry ; Mice ; Organ Size/drug effects
Czasopismo naukowe
Tytuł:
Withania frutescens. L Extract: Phytochemical Characterization and Acute and Repeated Dose 28-Day Oral Toxicity Studies in Mice.
Autorzy:
Moussaoui AE; Laboratory of Biotechnology, Environment, Agrifood and Health, Faculty of Sciences, University of Sidi Mohamed Ben Abdellah, Fez, Morocco.
Bourhia M; Laboratory of Chemistry-Biochemistry, Environment, Nutrition, and Health, Faculty of Medicine and Pharmacy, University of Casablanca, B.P 5696 Casablanca, Morocco.
Jawhari FZ; Laboratory of Biotechnology, Environment, Agrifood and Health, Faculty of Sciences, University of Sidi Mohamed Ben Abdellah, Fez, Morocco.
Es-Safi I; Laboratory of Biotechnology, Environment, Agrifood and Health, Faculty of Sciences, University of Sidi Mohamed Ben Abdellah, Fez, Morocco.
Ali SS; Department of Pharmaceutical Chemistry and Central Laboratory, College of Pharmacy King Saud University, Riyadh, Saudi Arabia.
Bari A; Department of Pharmaceutical Chemistry and Central Laboratory, College of Pharmacy King Saud University, Riyadh, Saudi Arabia.
Mahmood HM; Department of Pharmacology, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Bousta D; Laboratory of Biotechnology, Environment, Agrifood and Health, Faculty of Sciences, University of Sidi Mohamed Ben Abdellah, Fez, Morocco.
Bari A; Laboratory of Biotechnology, Environment, Agrifood and Health, Faculty of Sciences, University of Sidi Mohamed Ben Abdellah, Fez, Morocco.
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Źródło:
BioMed research international [Biomed Res Int] 2020 Sep 26; Vol. 2020, pp. 1976298. Date of Electronic Publication: 2020 Sep 26 (Print Publication: 2020).
Typ publikacji:
Journal Article
MeSH Terms:
Toxicity Tests, Acute*
Phytochemicals/*analysis
Plant Extracts/*administration & dosage
Plant Extracts/*toxicity
Withania/*chemistry
Administration, Oral ; Animals ; Body Weight/drug effects ; Gas Chromatography-Mass Spectrometry ; Mice ; Organ Size/drug effects ; Organ Specificity/drug effects ; Plant Roots/chemistry
Czasopismo naukowe
Tytuł:
β-Phenylethylamine and various monomethylated and para-halogenated analogs. Acute toxicity studies in mice.
Autorzy:
Mosnaim AD; Department of Cellular and Molecular Pharmacology, The Chicago Medical School at Rosalind Franklin University of Medicine and Science, N. Chicago, IL, USA.
Wolf ME; International Neuropsychiatry Consultants, Highland Park, IL, USA.
Iii O'Donnell JJ; Department of Cellular and Molecular Pharmacology, The Chicago Medical School at Rosalind Franklin University of Medicine and Science, N. Chicago, IL, USA.
Hudzik T; Safety Pharmacology, Collegeville, PA, USA.
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Źródło:
Drug and chemical toxicology [Drug Chem Toxicol] 2020 Jul; Vol. 43 (4), pp. 369-372. Date of Electronic Publication: 2019 Jan 07.
Typ publikacji:
Journal Article
MeSH Terms:
Toxicity Tests, Acute*
Phenethylamines/*toxicity
Animals ; Lethal Dose 50 ; Male ; Mice
Czasopismo naukowe
Tytuł:
The Comparative Toxicity of 10 Microcystin Congeners Administered Orally to Mice: Clinical Effects and Organ Toxicity.
Autorzy:
Chernoff N; Center for Public Health & Environmental Assessment, U.S. Environmental Protection Agency, Research Triangle Park, NC 27711, USA.
Hill D; Center for Public Health & Environmental Assessment, U.S. Environmental Protection Agency, Research Triangle Park, NC 27711, USA.
Lang J; Oak Ridge Institute for Science and Education, Oak Ridge, TN 37830, USA.
Schmid J; Center for Public Health & Environmental Assessment, U.S. Environmental Protection Agency, Research Triangle Park, NC 27711, USA.
Le T; Oak Ridge Institute for Science and Education, Oak Ridge, TN 37830, USA.
Farthing A; Oak Ridge Institute for Science and Education, Oak Ridge, TN 37830, USA.
Huang H; Oak Ridge Institute for Science and Education, Oak Ridge, TN 37830, USA.
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Źródło:
Toxins [Toxins (Basel)] 2020 Jun 18; Vol. 12 (6). Date of Electronic Publication: 2020 Jun 18.
Typ publikacji:
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Toxicity Tests, Acute*
Chemical and Drug Induced Liver Injury/*etiology
Liver/*drug effects
Microcystins/*toxicity
Administration, Oral ; Animals ; Chemical and Drug Induced Liver Injury/metabolism ; Chemical and Drug Induced Liver Injury/pathology ; Dose-Response Relationship, Drug ; Female ; Liver/metabolism ; Liver/pathology ; Male ; Mice, Inbred BALB C ; Microcystins/administration & dosage
Czasopismo naukowe
Tytuł:
In vitro evaluation of magnetite nanoparticles in human mesenchymal stem cells: comparison of different cytotoxicity assays.
Autorzy:
De Simone U; Laboratory of Clinical and Experimental Toxicology, Toxicology Unit, ICS Maugeri SpA-SB, IRCCS, Pavia, Italy.
Spinillo A; Department of Obstetrics and Gynecology, Fondazione IRCCS Policlinico San Matteo and University of Pavia, Pavia, Italy.
Caloni F; Department of Veterinary Medicine (DIMEVET), Università degli Studi di Milano, Milano, Italy.
Avanzini MA; Laboratory of Transplant Immunology/Cell Factory, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Coccini T; Laboratory of Clinical and Experimental Toxicology, Toxicology Unit, ICS Maugeri SpA-SB, IRCCS, Pavia, Italy.
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Źródło:
Toxicology mechanisms and methods [Toxicol Mech Methods] 2020 Jan; Vol. 30 (1), pp. 48-59. Date of Electronic Publication: 2019 Aug 19.
Typ publikacji:
Comparative Study; Journal Article
MeSH Terms:
Biological Assay*
Toxicity Tests, Acute*
Magnetite Nanoparticles/*toxicity
Mesenchymal Stem Cells/*drug effects
Cell Survival/drug effects ; Cells, Cultured ; Dose-Response Relationship, Drug ; Humans ; Mesenchymal Stem Cells/metabolism ; Mesenchymal Stem Cells/pathology ; Risk Assessment ; Time Factors
Czasopismo naukowe
Tytuł:
Acute and Subacute Toxicity Studies of the Ethyl Acetate Soluble Proanthocyanidins of the Immature Inflorescence of Cocos nucifera L. in Female Wistar Rats.
Autorzy:
Ekanayake CP; Department of Chemistry, Faculty of Applied Sciences and Centre for Plant Materials and Herbal Products Research, University of Sri Jayewardenepura, Gangodawila, Nugegoda, Sri Lanka.
Thammitiyagodage MG; Animal Centre, Medical Research Institute, Colombo 08, Sri Lanka.
Padumadasa S; Department of Obstetrics and Gynaecology, Faculty of Medicine, University of Kelaniya, Sri Lanka.
Seneviratne B; Department of Pathology, Faculty of Medical Sciences, University of Sri Jayewardenepura, Gangodawila, Nugegoda, Sri Lanka.
Padumadasa C; Department of Chemistry, Faculty of Applied Sciences and Centre for Plant Materials and Herbal Products Research, University of Sri Jayewardenepura, Gangodawila, Nugegoda, Sri Lanka.
Abeysekera AM; Department of Chemistry, Faculty of Applied Sciences and Centre for Plant Materials and Herbal Products Research, University of Sri Jayewardenepura, Gangodawila, Nugegoda, Sri Lanka.
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Źródło:
BioMed research international [Biomed Res Int] 2019 Dec 03; Vol. 2019, pp. 8428304. Date of Electronic Publication: 2019 Dec 03 (Print Publication: 2019).
Typ publikacji:
Journal Article
MeSH Terms:
Toxicity Tests, Acute*
Acetates/*chemistry
Cocos/*chemistry
Inflorescence/*chemistry
Proanthocyanidins/*toxicity
Animals ; Body Weight/drug effects ; Drinking Behavior/drug effects ; Feeding Behavior/drug effects ; Female ; Organ Size/drug effects ; Proanthocyanidins/isolation & purification ; Rats, Wistar
Czasopismo naukowe
Tytuł:
Analyses of the toxic properties of recombinant human Cyclophilin A in mice.
Autorzy:
Kalinina A; Federal State Budgetary Institution, N.N. Blokhin National Medical Research Center of Oncology оf the Ministry of Health of the Russian Federation , Moscow , Russia.
Zamkova M; Federal State Budgetary Institution, N.N. Blokhin National Medical Research Center of Oncology оf the Ministry of Health of the Russian Federation , Moscow , Russia.
Antoshina E; Federal State Budgetary Institution, N.N. Blokhin National Medical Research Center of Oncology оf the Ministry of Health of the Russian Federation , Moscow , Russia.
Trukhanova L; Federal State Budgetary Institution, N.N. Blokhin National Medical Research Center of Oncology оf the Ministry of Health of the Russian Federation , Moscow , Russia.
Gorkova T; Federal State Budgetary Institution, N.N. Blokhin National Medical Research Center of Oncology оf the Ministry of Health of the Russian Federation , Moscow , Russia.
Kazansky D; Federal State Budgetary Institution, N.N. Blokhin National Medical Research Center of Oncology оf the Ministry of Health of the Russian Federation , Moscow , Russia.
Khromykh L; Federal State Budgetary Institution, N.N. Blokhin National Medical Research Center of Oncology оf the Ministry of Health of the Russian Federation , Moscow , Russia.
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Źródło:
Journal of immunotoxicology [J Immunotoxicol] 2019 Dec; Vol. 16 (1), pp. 182-190.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Toxicity Tests, Acute*
Acute Kidney Injury/*chemically induced
Acute-Phase Proteins/*metabolism
Cyclophilin A/*toxicity
Acute Kidney Injury/blood ; Acute Kidney Injury/immunology ; Acute-Phase Proteins/immunology ; Animals ; Cyclophilin A/administration & dosage ; Cyclophilin A/isolation & purification ; Disease Models, Animal ; Dose-Response Relationship, Drug ; Female ; Gene Expression/drug effects ; Gene Expression/immunology ; Gene Expression Profiling ; Granulocytes ; Humans ; Injections, Intraperitoneal ; Injections, Subcutaneous ; Kidney/drug effects ; Kidney/immunology ; Kidney/pathology ; Lethal Dose 50 ; Lymphocyte Count ; Male ; Mice ; Recombinant Proteins/administration & dosage ; Recombinant Proteins/isolation & purification ; Recombinant Proteins/toxicity
Czasopismo naukowe
Tytuł:
Acute Methylmercury Exposure and the Hypoxia-Inducible Factor- 1 α Signaling Pathway under Normoxic Conditions in the Rat Brain and Astrocytes in Vitro .
Autorzy:
Chang J; Department of Preventive Medicine and Public Health Laboratory Sciences, School of Medicine, Jiangsu University, Zhenjiang, China.
Yang B; Department of Preventive Medicine and Public Health Laboratory Sciences, School of Medicine, Jiangsu University, Zhenjiang, China.
Zhou Y; Department of Preventive Medicine and Public Health Laboratory Sciences, School of Medicine, Jiangsu University, Zhenjiang, China.
Yin C; Department of Preventive Medicine and Public Health Laboratory Sciences, School of Medicine, Jiangsu University, Zhenjiang, China.; Institute of Life Sciences, Jiangsu University, Zhenjiang, China.
Liu T; Department of Preventive Medicine and Public Health Laboratory Sciences, School of Medicine, Jiangsu University, Zhenjiang, China.
Qian H; Department of Preventive Medicine and Public Health Laboratory Sciences, School of Medicine, Jiangsu University, Zhenjiang, China.
Xing G; Department of Preventive Medicine and Public Health Laboratory Sciences, School of Medicine, Jiangsu University, Zhenjiang, China.
Wang S; Department of Preventive Medicine and Public Health Laboratory Sciences, School of Medicine, Jiangsu University, Zhenjiang, China.
Li F; Department of Preventive Medicine and Public Health Laboratory Sciences, School of Medicine, Jiangsu University, Zhenjiang, China.
Zhang Y; Department of Occupational Health and Toxicology, School of Public Health, Fudan University, Shanghai, China.
Chen D; School of Environment, Guangdong Key Laboratory of Environmental Pollution and Health, Jinan University, Guangzhou, China.
Aschner M; Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, New York, USA.
Lu R; Department of Preventive Medicine and Public Health Laboratory Sciences, School of Medicine, Jiangsu University, Zhenjiang, China.; Center for Experimental Research, Kunshan Hospital Affiliated to Jiangsu University, Kunshan, China.
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Źródło:
Environmental health perspectives [Environ Health Perspect] 2019 Dec; Vol. 127 (12), pp. 127006. Date of Electronic Publication: 2019 Dec 18.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Toxicity Tests, Acute*
Environmental Pollutants/*toxicity
Methylmercury Compounds/*toxicity
Animals ; Astrocytes ; Brain ; Cell Proliferation ; Cell Survival ; Gene Expression Regulation ; Hypoxia ; Hypoxia-Inducible Factor 1, alpha Subunit ; RNA, Messenger/metabolism ; Rats ; Reactive Oxygen Species/metabolism ; Signal Transduction ; Transcriptional Activation ; Up-Regulation ; Vascular Endothelial Growth Factor A
Czasopismo naukowe
Tytuł:
Usnic Acid Potassium Salt: Evaluation of the Acute Toxicity and Antinociceptive Effect in Murine Model.
Autorzy:
Araújo HDA; Centro de Biociências-Departamento de Bioquímica, Universidade Federal de Pernambuco, Avenida Prof. Moraes Rego, 1235, Cidade Universitária, Recife-PE 50.670-501, Brazil. .
Silva Júnior JG; Centro de Biociências-Departamento de Bioquímica, Universidade Federal de Pernambuco, Avenida Prof. Moraes Rego, 1235, Cidade Universitária, Recife-PE 50.670-501, Brazil. .
Saturnino Oliveira JR; Centro de Biociências-Departamento de Bioquímica, Universidade Federal de Pernambuco, Avenida Prof. Moraes Rego, 1235, Cidade Universitária, Recife-PE 50.670-501, Brazil. .
Helena M L Ribeiro M; Laboratório de Imunopatologia Keizo Asami (LIKA), Universidade Federal de Pernambuco. Avenida Prof. Moraes Rego, 1235 Cidade Universitária, Recife-PE 50.670-501, Brazil. .
C Barroso Martins M; Centro de Biociências-Departamento de Bioquímica, Universidade Federal de Pernambuco, Avenida Prof. Moraes Rego, 1235, Cidade Universitária, Recife-PE 50.670-501, Brazil. .
Cavalcanti Bezerra MA; Centro de Biociências-Departamento de Biofísica e Radiobiologia, Universidade Federal de Pernambuco. Avenida Prof. Moraes Rego, 1235 Cidade Universitária, Recife-PE 50.670-501, Brazil. .
Lima Aires A; Laboratório de Imunopatologia Keizo Asami (LIKA), Universidade Federal de Pernambuco. Avenida Prof. Moraes Rego, 1235 Cidade Universitária, Recife-PE 50.670-501, Brazil. .; Centro de Ciências da Saúde-Departamento de Medicina Tropical, Universidade Federal de Pernambuco. Avenida Prof. Moraes Rego, 1235 Cidade Universitária, Recife-PE 50.670-501, Brazil. .
C P Azevedo Albuquerque M; Laboratório de Imunopatologia Keizo Asami (LIKA), Universidade Federal de Pernambuco. Avenida Prof. Moraes Rego, 1235 Cidade Universitária, Recife-PE 50.670-501, Brazil. .; Centro de Ciências da Saúde-Departamento de Medicina Tropical, Universidade Federal de Pernambuco. Avenida Prof. Moraes Rego, 1235 Cidade Universitária, Recife-PE 50.670-501, Brazil. .
Melo-Júnior MR; Laboratório de Imunopatologia Keizo Asami (LIKA), Universidade Federal de Pernambuco. Avenida Prof. Moraes Rego, 1235 Cidade Universitária, Recife-PE 50.670-501, Brazil. .; Centro de Ciências da Saúde-Departamento de Patologia, Universidade Federal de Pernambuco. Avenida Prof. Moraes Rego, 1235 Cidade Universitária, Recife-PE 50.670-501, Brazil. .
Pontes Filho NT; Laboratório de Imunopatologia Keizo Asami (LIKA), Universidade Federal de Pernambuco. Avenida Prof. Moraes Rego, 1235 Cidade Universitária, Recife-PE 50.670-501, Brazil. .; Centro de Ciências da Saúde-Departamento de Patologia, Universidade Federal de Pernambuco. Avenida Prof. Moraes Rego, 1235 Cidade Universitária, Recife-PE 50.670-501, Brazil. .
Pereira EC; Departamento de Ciências Geográficas, Centro de Filosofia e Ciências Humanas, Universidade Federal de Pernambuco, Recife-PE 50.740-530, Brazil. .
Raposo Silva DJ; Departamento de Química Fundamental, Universidade Federal de Pernambuco, Recife-PE 50.740-540, Brazil. .
Dos Anjos JV; Departamento de Química Fundamental, Universidade Federal de Pernambuco, Recife-PE 50.740-540, Brazil. .
Falcão EPS; Laboratório de Síntese e Isolamento Molecular, Centro Acadêmico de Vitória de Santo Antão, Universidade Federal de Pernambuco, Vitória de Santo Antão-PE 55.608-680, Brazil. emerson_.
Silva NH; Centro de Biociências-Departamento de Bioquímica, Universidade Federal de Pernambuco, Avenida Prof. Moraes Rego, 1235, Cidade Universitária, Recife-PE 50.670-501, Brazil. .
Menezes Lima VL; Centro de Biociências-Departamento de Bioquímica, Universidade Federal de Pernambuco, Avenida Prof. Moraes Rego, 1235, Cidade Universitária, Recife-PE 50.670-501, Brazil. .
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2019 May 28; Vol. 24 (11). Date of Electronic Publication: 2019 May 28.
Typ publikacji:
Journal Article
MeSH Terms:
Toxicity Tests, Acute*
Analgesics/*pharmacology
Benzofurans/*pharmacology
Benzofurans/*toxicity
Animals ; Behavior, Animal/drug effects ; Benzofurans/chemistry ; Disease Models, Animal ; Drinking Behavior ; Feeding Behavior ; Female ; Mice ; Molecular Conformation ; Organ Specificity/drug effects
Czasopismo naukowe
Tytuł:
Nonanimal Models for Acute Toxicity Evaluations: Applying Data-Driven Profiling and Read-Across.
Autorzy:
Russo DP; 1 Center for Computational and Integrative Biology, Rutgers University , Camden, New Jersey, USA.
Strickland J; 2 Integrated Laboratory Systems (ILS) , Research Triangle Park, North Carolina, USA.
Karmaus AL; 2 Integrated Laboratory Systems (ILS) , Research Triangle Park, North Carolina, USA.
Wang W; 1 Center for Computational and Integrative Biology, Rutgers University , Camden, New Jersey, USA.
Shende S; 1 Center for Computational and Integrative Biology, Rutgers University , Camden, New Jersey, USA.; 3 Department of Computer Science, Rutgers University , Camden, New Jersey, USA.
Hartung T; 4 Johns Hopkins Bloomberg School of Public Health, Center for Alternatives to Animal Testing (CAAT) , Baltimore, Maryland, USA.; 5 University of Konstanz, CAAT-Europe , Konstanz, Germany.
Aleksunes LM; 6 Department of Pharmacology and Toxicology, Ernest Mario School of Pharmacy, Rutgers University , Piscataway, New Jersey, USA.
Zhu H; 1 Center for Computational and Integrative Biology, Rutgers University , Camden, New Jersey, USA.; 7 Department of Chemistry, Rutgers University , Camden, New Jersey, USA.
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Źródło:
Environmental health perspectives [Environ Health Perspect] 2019 Apr; Vol. 127 (4), pp. 47001.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Animal Testing Alternatives/*statistics & numerical data
Computational Biology/*methods
High-Throughput Screening Assays/*methods
Toxicity Tests, Acute/*methods
Animals ; Computational Biology/instrumentation ; Hazardous Substances ; Humans ; Rats ; Toxicity Tests, Acute/instrumentation
Czasopismo naukowe
Tytuł:
Sublethal effects of imidacloprid on the performance of the bird cherry-oat aphid Rhopalosiphum padi.
Autorzy:
Li W; Institute of Plant Protection, Shandong Academy of Agricultural Sciences, Jinan, China.; College of Plant Protection, Shandong Agricultural University, Tai'an, China.
Lu Z; Maize Research Institute, Shandong Academy of Agricultural Sciences, National Engineering Laboratory of Wheat and Maize, Key Laboratory of Biology and Genetic Improvement of Maize in Northern Yellow-Huai River Plain, Ministry of Agriculture, China, Jinan, China.
Li L; Institute of Plant Protection, Shandong Academy of Agricultural Sciences, Jinan, China.
Yu Y; Institute of Plant Protection, Shandong Academy of Agricultural Sciences, Jinan, China.
Dong S; Institute of Plant Protection, Shandong Academy of Agricultural Sciences, Jinan, China.; College of Plant Protection, Shandong Agricultural University, Tai'an, China.
Men X; Institute of Plant Protection, Shandong Academy of Agricultural Sciences, Jinan, China.
Ye B; College of Plant Protection, Shandong Agricultural University, Tai'an, China.
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Źródło:
PloS one [PLoS One] 2018 Sep 20; Vol. 13 (9), pp. e0204097. Date of Electronic Publication: 2018 Sep 20 (Print Publication: 2018).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Toxicity Tests, Acute*
Aphids/*drug effects
Avena/*parasitology
Neonicotinoids/*toxicity
Nitro Compounds/*toxicity
Animals ; Aphids/enzymology ; Aphids/growth & development ; Female ; Fertility/drug effects ; Reproduction/drug effects
Czasopismo naukowe
Tytuł:
Assessment of the lethal and sublethal effects by spinetoram on cotton bollworm.
Autorzy:
Wei J; State key Laboratory of Wheat and Maize Crop Science/College of Plant Protection, Henan Agricultural University, Zhengzhou, China.
Zhang L; State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, China.
Yang S; State key Laboratory of Wheat and Maize Crop Science/College of Plant Protection, Henan Agricultural University, Zhengzhou, China.
Xie B; State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, China.
An S; State key Laboratory of Wheat and Maize Crop Science/College of Plant Protection, Henan Agricultural University, Zhengzhou, China.
Liang G; State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, China.
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Źródło:
PloS one [PLoS One] 2018 Sep 14; Vol. 13 (9), pp. e0204154. Date of Electronic Publication: 2018 Sep 14 (Print Publication: 2018).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Toxicity Tests, Acute*
Gossypium/*parasitology
Macrolides/*toxicity
Moths/*drug effects
Animals ; Bacillus thuringiensis Toxins ; Bacterial Proteins/toxicity ; Body Weight/drug effects ; Endotoxins/toxicity ; Fertility/drug effects ; Hemolysin Proteins/toxicity ; Insecticide Resistance/drug effects ; Larva/drug effects ; Moths/physiology ; Pupa/drug effects
Czasopismo naukowe
Tytuł:
Subacute Oral Administration of Clinacanthus nutans Ethanolic Leaf Extract Induced Liver and Kidney Toxicities in ICR Mice.
Autorzy:
Aliyu A; Department of Veterinary Pathology and Microbiology, Faculty of Veterinary Medicine, Universiti Putra Malaysia, Serdang 43400, Selangor, Malaysia.; Department of Veterinary Pathology, Faculty of Veterinary Medicine, City Campus Complex, Usmanu Danfodiyo University, Sokoto 840212, Sokoto State, Nigeria.
Shaari MR; Animal Science Research Centre, Malaysian Agricultural Research and Development Institute Headquarter, Serdang 43400, Selangor, Malaysia.
Ahmad Sayuti NS; Department of Veterinary Pathology and Microbiology, Faculty of Veterinary Medicine, Universiti Putra Malaysia, Serdang 43400, Selangor, Malaysia.
Reduan MFH; Department of Veterinary Pathology and Microbiology, Faculty of Veterinary Medicine, Universiti Putra Malaysia, Serdang 43400, Selangor, Malaysia.
Sithambaram S; Animal Science Research Centre, Malaysian Agricultural Research and Development Institute Headquarter, Serdang 43400, Selangor, Malaysia.
Noordin MM; Department of Veterinary Pathology and Microbiology, Faculty of Veterinary Medicine, Universiti Putra Malaysia, Serdang 43400, Selangor, Malaysia.
Shaari K; Department of Chemistry, Faculty of Science and Environmental Studies, Universiti Putra Malaysia, Serdang 43400, Selangor, Malaysia.; Laboratory of Natural Products, Institute of Bioscience, Universiti Putra Malaysia, Serdang 43400, Selangor, Malaysia.
Hamzah H; Department of Veterinary Pathology and Microbiology, Faculty of Veterinary Medicine, Universiti Putra Malaysia, Serdang 43400, Selangor, Malaysia.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2020 Jun 05; Vol. 25 (11). Date of Electronic Publication: 2020 Jun 05.
Typ publikacji:
Journal Article
MeSH Terms:
Acanthaceae/*chemistry
Chemical and Drug Induced Liver Injury/*pathology
Kidney/*pathology
Plant Extracts/*administration & dosage
Plant Extracts/*toxicity
Plant Leaves/*chemistry
Toxicity Tests, Acute/*methods
Administration, Oral ; Animals ; Chemical and Drug Induced Liver Injury/etiology ; Female ; Kidney/drug effects ; Lethal Dose 50 ; Male ; Mice ; Mice, Inbred ICR
Czasopismo naukowe

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