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Wyszukujesz frazę ""Trabecular Meshwork"" wg kryterium: Temat


Tytuł :
[The trabecular meshwork: Structure, function and clinical implications. A review of the littérature (French translation of the article)].
Autorzy :
Buffault J; Service d'ophtalmologie, centre hospitalier national d'ophtalmologie des Quinze-Vingts, IHU FOReSIGHT, 28, rue de Charenton, 75012 Paris, France. Electronic address: .
Labbé A; Service d'ophtalmologie, centre hospitalier national d'ophtalmologie des Quinze-Vingts, IHU FOReSIGHT, 28, rue de Charenton, 75012 Paris, France; Service d'ophtalmologie, hôpital Ambroise-Paré, AP-HP, 9, avenue Charles-de-Gaulle, 92100 Boulogne-Billancourt, France; Inserm, CNRS, institut de la vision, Sorbonne université, 17, rue Moreau, 75012 Paris, France.
Hamard P; Service d'ophtalmologie, centre hospitalier national d'ophtalmologie des Quinze-Vingts, IHU FOReSIGHT, 28, rue de Charenton, 75012 Paris, France.
Brignole-Baudouin F; Inserm, CNRS, institut de la vision, Sorbonne université, 17, rue Moreau, 75012 Paris, France; Service de biologie médicale, centre hospitalier national d'ophtalmologie des Quinze-Vingts, IHU FOReSIGHT, 28, rue de Charenton, 75012 Paris, France.
Baudouin C; Service d'ophtalmologie, centre hospitalier national d'ophtalmologie des Quinze-Vingts, IHU FOReSIGHT, 28, rue de Charenton, 75012 Paris, France; Service d'ophtalmologie, hôpital Ambroise-Paré, AP-HP, 9, avenue Charles-de-Gaulle, 92100 Boulogne-Billancourt, France; Inserm, CNRS, institut de la vision, Sorbonne université, 17, rue Moreau, 75012 Paris, France.
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Transliterated Title :
Le trabéculum : structure, fonction et implications cliniques. Une revue de la littérature.
Źródło :
Journal francais d'ophtalmologie [J Fr Ophtalmol] 2020 Oct; Vol. 43 (8), pp. 779-793. Date of Electronic Publication: 2020 Aug 15.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Glaucoma/*etiology
Trabecular Meshwork/*chemistry
Trabecular Meshwork/*physiology
Glaucoma/pathology ; Glaucoma/physiopathology ; Humans ; Intraocular Pressure/physiology ; Optic Nerve Diseases/pathology ; Optic Nerve Diseases/physiopathology ; Trabecular Meshwork/cytology ; Trabecular Meshwork/pathology
Czasopismo naukowe
Tytuł :
Disruption of fibronectin fibrillogenesis affects intraocular pressure (IOP) in BALB/cJ mice.
Autorzy :
Faralli JA; Department of Pathology and Laboratory Medicine, School of Medicine and Public Health, University of Wisconsin, Madison, Wisconsin, United States of America.
Filla MS; Department of Pathology and Laboratory Medicine, School of Medicine and Public Health, University of Wisconsin, Madison, Wisconsin, United States of America.
McDowell CM; Department of Ophthalmology and Visual Sciences, School of Medicine and Public Health, University of Wisconsin, Madison, Wisconsin, United States of America.
Peters DM; Department of Pathology and Laboratory Medicine, School of Medicine and Public Health, University of Wisconsin, Madison, Wisconsin, United States of America.; Department of Ophthalmology and Visual Sciences, School of Medicine and Public Health, University of Wisconsin, Madison, Wisconsin, United States of America.
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Źródło :
PloS one [PLoS One] 2020 Aug 21; Vol. 15 (8), pp. e0237932. Date of Electronic Publication: 2020 Aug 21 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Fibronectins/*metabolism
Intraocular Pressure/*drug effects
Ocular Hypertension/*metabolism
Peptides/*therapeutic use
Trabecular Meshwork/*drug effects
Adolescent ; Adult ; Animals ; Cells, Cultured ; Extracellular Matrix/drug effects ; Extracellular Matrix/metabolism ; Female ; Fibronectins/chemistry ; Humans ; Male ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Ocular Hypertension/chemically induced ; Ocular Hypertension/drug therapy ; Peptides/metabolism ; Peptides/pharmacology ; Trabecular Meshwork/cytology ; Trabecular Meshwork/metabolism ; Transforming Growth Factor beta2/metabolism ; Transforming Growth Factor beta2/toxicity
Czasopismo naukowe
Tytuł :
Schlemm Canal and Trabecular Meshwork Features in Highly Myopic Eyes With Early Intraocular Pressure Elevation After Cataract Surgery.
Autorzy :
Qi J; Department of Ophthalmology, Eye, Ear, Nose, and Throat Hospital of Fudan University, Shanghai, People's Republic of China; Key Laboratory of Myopia, Ministry of Health, People's Republic of China; Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, People's Republic of China; Shanghai High Myopia Study Group, Shanghai, People's Republic of China; Visual Rehabilitation Professional Committee, Chinese Association of Rehabilitation Medicine, Shanghai, People's Republic of China.
He W; Department of Ophthalmology, Eye, Ear, Nose, and Throat Hospital of Fudan University, Shanghai, People's Republic of China; Key Laboratory of Myopia, Ministry of Health, People's Republic of China; Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, People's Republic of China; Shanghai High Myopia Study Group, Shanghai, People's Republic of China; Visual Rehabilitation Professional Committee, Chinese Association of Rehabilitation Medicine, Shanghai, People's Republic of China.
Lu Q; Department of Ophthalmology, Eye, Ear, Nose, and Throat Hospital of Fudan University, Shanghai, People's Republic of China; Key Laboratory of Myopia, Ministry of Health, People's Republic of China; Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, People's Republic of China; Shanghai High Myopia Study Group, Shanghai, People's Republic of China; Visual Rehabilitation Professional Committee, Chinese Association of Rehabilitation Medicine, Shanghai, People's Republic of China.
Zhang K; Department of Ophthalmology, Eye, Ear, Nose, and Throat Hospital of Fudan University, Shanghai, People's Republic of China; Key Laboratory of Myopia, Ministry of Health, People's Republic of China; Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, People's Republic of China; Shanghai High Myopia Study Group, Shanghai, People's Republic of China; Visual Rehabilitation Professional Committee, Chinese Association of Rehabilitation Medicine, Shanghai, People's Republic of China.
Lu Y; Department of Ophthalmology, Eye, Ear, Nose, and Throat Hospital of Fudan University, Shanghai, People's Republic of China; Key Laboratory of Myopia, Ministry of Health, People's Republic of China; Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, People's Republic of China; Shanghai High Myopia Study Group, Shanghai, People's Republic of China; Visual Rehabilitation Professional Committee, Chinese Association of Rehabilitation Medicine, Shanghai, People's Republic of China.
Zhu X; Department of Ophthalmology, Eye, Ear, Nose, and Throat Hospital of Fudan University, Shanghai, People's Republic of China; Key Laboratory of Myopia, Ministry of Health, People's Republic of China; Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, People's Republic of China; Shanghai High Myopia Study Group, Shanghai, People's Republic of China; Visual Rehabilitation Professional Committee, Chinese Association of Rehabilitation Medicine, Shanghai, People's Republic of China. Electronic address: .
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Źródło :
American journal of ophthalmology [Am J Ophthalmol] 2020 Aug; Vol. 216, pp. 193-200. Date of Electronic Publication: 2020 Feb 14.
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Anterior Chamber/*pathology
Intraocular Pressure/*physiology
Myopia, Degenerative/*complications
Ocular Hypertension/*etiology
Phacoemulsification/*adverse effects
Trabecular Meshwork/*pathology
Aged ; Anterior Chamber/diagnostic imaging ; Case-Control Studies ; Cataract/etiology ; Female ; Humans ; Lens Implantation, Intraocular ; Male ; Middle Aged ; Ocular Hypertension/physiopathology ; Retrospective Studies ; Risk Factors ; Tomography, Optical Coherence ; Trabecular Meshwork/diagnostic imaging
Czasopismo naukowe
Tytuł :
Ex-vivo cultured human corneoscleral segment model to study the effects of glaucoma factors on trabecular meshwork.
Autorzy :
Kasetti RB; Department of Pharmacology and Neuroscience and the North Texas Eye Research Institute, University of North Texas Health Science Center at Fort Worth, Fort Worth, TX, United States of America.
Patel PD; Department of Pharmacology and Neuroscience and the North Texas Eye Research Institute, University of North Texas Health Science Center at Fort Worth, Fort Worth, TX, United States of America.
Maddineni P; Department of Pharmacology and Neuroscience and the North Texas Eye Research Institute, University of North Texas Health Science Center at Fort Worth, Fort Worth, TX, United States of America.
Zode GS; Department of Pharmacology and Neuroscience and the North Texas Eye Research Institute, University of North Texas Health Science Center at Fort Worth, Fort Worth, TX, United States of America.
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Źródło :
PloS one [PLoS One] 2020 Jun 24; Vol. 15 (6), pp. e0232111. Date of Electronic Publication: 2020 Jun 24 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Dexamethasone/*pharmacology
Limbus Corneae/*metabolism
Trabecular Meshwork/*drug effects
Transforming Growth Factor beta2/*pharmacology
Apoptosis/drug effects ; Cells, Cultured ; Cytoskeletal Proteins/genetics ; Cytoskeletal Proteins/metabolism ; Endoplasmic Reticulum Stress/drug effects ; Extracellular Matrix Proteins/metabolism ; Eye Proteins/genetics ; Eye Proteins/metabolism ; Glaucoma, Open-Angle/pathology ; Glycoproteins/genetics ; Glycoproteins/metabolism ; Humans ; Limbus Corneae/cytology ; Limbus Corneae/drug effects ; Trabecular Meshwork/metabolism ; Trabecular Meshwork/pathology ; Up-Regulation/drug effects
Czasopismo naukowe
Tytuł :
Molecular taxonomy of human ocular outflow tissues defined by single-cell transcriptomics.
Autorzy :
Patel G; Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591.
Fury W; Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591.
Yang H; Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591.
Gomez-Caraballo M; Department of Ophthalmology, Duke University, Durham, NC 27710.
Bai Y; Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591.
Yang T; Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591.
Adler C; Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591.
Wei Y; Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591.
Ni M; Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591.
Schmitt H; Department of Ophthalmology, Duke University, Durham, NC 27710.
Hu Y; Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591.
Yancopoulos G; Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591.
Stamer WD; Department of Ophthalmology, Duke University, Durham, NC 27710 .
Romano C; Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591; .
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Jun 09; Vol. 117 (23), pp. 12856-12867. Date of Electronic Publication: 2020 May 21.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Aqueous Humor/*metabolism
Glaucoma/*pathology
Intraocular Pressure/*physiology
Myofibroblasts/*metabolism
Trabecular Meshwork/*metabolism
Glaucoma/genetics ; Humans ; Macrophages/metabolism ; RNA-Seq ; Schwann Cells/metabolism ; Single-Cell Analysis ; Trabecular Meshwork/cytology
Czasopismo naukowe
Tytuł :
Rho-associated protein kinase inhibitor induced morphological changes in type VI collagen in the human trabecular meshwork.
Autorzy :
Okamoto M; Ophthalmology, Tokai University Hachioji Hospital, Hachioji, Japan.
Nagahara M; Ophthalmology, National Center for Global Health and Medicine Hospital, Shinjuku-ku, Japan .
Tajiri T; Diagnostic Pathology, Tokai University Hachioji Hospital, Hachioji, Japan.
Nakamura N; Diagnostic Pathology, Tokai University School of Health Sciences, Isehara, Japan.
Fukunishi N; Support Center for Medical Research and Education, Tokai University School of Health Sciences, Isehara, Japan.
Nagahara K; Mathematics, Tokyo Institute of Technology-Ookayama Campus, Meguro-ku, Japan.
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Źródło :
The British journal of ophthalmology [Br J Ophthalmol] 2020 Mar; Vol. 104 (3), pp. 392-397. Date of Electronic Publication: 2019 Jun 14.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Collagen Type VI/*metabolism
Glaucoma, Open-Angle/*drug therapy
Intraocular Pressure/*physiology
Isoquinolines/*administration & dosage
Sulfonamides/*administration & dosage
Trabecular Meshwork/*metabolism
Aged ; Aged, 80 and over ; Biomarkers/metabolism ; Cross-Sectional Studies ; Female ; Glaucoma, Open-Angle/metabolism ; Glaucoma, Open-Angle/physiopathology ; Humans ; Male ; Middle Aged ; Ophthalmic Solutions ; Retrospective Studies ; Trabecular Meshwork/drug effects ; Trabecular Meshwork/ultrastructure ; rho-Associated Kinases/antagonists & inhibitors
Czasopismo naukowe
Tytuł :
Effect and Mechanism of Phosphodiesterase Inhibitors on Trabecular Outflow.
Autorzy :
Kim JW; Department of Ophthalmology, Daegu Catholic University School of Medicine, Daegu, Korea. .
Lee JB; Department of Ophthalmology, Daegu Catholic University School of Medicine, Daegu, Korea.
Lee SH; Department of Ophthalmology, Daegu Catholic University School of Medicine, Daegu, Korea.
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Źródło :
Korean journal of ophthalmology : KJO [Korean J Ophthalmol] 2019 Oct; Vol. 33 (5), pp. 414-421.
Typ publikacji :
Journal Article
MeSH Terms :
Adenosine/*metabolism
Dipyridamole/*pharmacology
Matrix Metalloproteinases/*metabolism
Nitric Oxide/*metabolism
Theophylline/*pharmacology
Trabecular Meshwork/*metabolism
Blotting, Western ; Cells, Cultured ; Humans ; Matrix Metalloproteinases/drug effects ; Phosphodiesterase Inhibitors/pharmacology ; Trabecular Meshwork/cytology ; Trabecular Meshwork/drug effects
Czasopismo naukowe
Tytuł :
CPAMD8 loss-of-function underlies non-dominant congenital glaucoma with variable anterior segment dysgenesis and abnormal extracellular matrix.
Autorzy :
Bonet-Fernández JM; Área de Genética, Facultad de Medicina de Albacete, Universidad de Castilla-La Mancha, Albacete, Spain.; Instituto de Investigación en Discapacidades Neurológicas (IDINE), Universidad de Castilla-La Mancha, Albacete, Spain.; Cooperative Research Network on Age-Related Ocular Pathology, Visual and Life Quality (OFTARED), Instituto de Salud Carlos III, Madrid, Spain.
Aroca-Aguilar JD; Área de Genética, Facultad de Medicina de Albacete, Universidad de Castilla-La Mancha, Albacete, Spain.; Instituto de Investigación en Discapacidades Neurológicas (IDINE), Universidad de Castilla-La Mancha, Albacete, Spain.; Cooperative Research Network on Age-Related Ocular Pathology, Visual and Life Quality (OFTARED), Instituto de Salud Carlos III, Madrid, Spain.
Corton M; Área de Genética and Genómica, Instituto de Investigación Sanitaria-Hospital Universitario Fundación Jiménez Díaz-Universidad Autónoma de Madrid (IIS-FJD, UAM), Madrid, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), Madrid, Spain.
Ramírez AI; Cooperative Research Network on Age-Related Ocular Pathology, Visual and Life Quality (OFTARED), Instituto de Salud Carlos III, Madrid, Spain.; Instituto de Investigaciones Oftalmológicas Ramón Castroviejo, Universidad Complutense de Madrid, Madrid, Spain.
Alexandre-Moreno S; Área de Genética, Facultad de Medicina de Albacete, Universidad de Castilla-La Mancha, Albacete, Spain.; Instituto de Investigación en Discapacidades Neurológicas (IDINE), Universidad de Castilla-La Mancha, Albacete, Spain.; Cooperative Research Network on Age-Related Ocular Pathology, Visual and Life Quality (OFTARED), Instituto de Salud Carlos III, Madrid, Spain.
García-Antón MT; Instituto de Investigaciones Oftalmológicas Ramón Castroviejo, Universidad Complutense de Madrid, Madrid, Spain.
Salazar JJ; Cooperative Research Network on Age-Related Ocular Pathology, Visual and Life Quality (OFTARED), Instituto de Salud Carlos III, Madrid, Spain.; Instituto de Investigaciones Oftalmológicas Ramón Castroviejo, Universidad Complutense de Madrid, Madrid, Spain.
Ferre-Fernández JJ; Área de Genética, Facultad de Medicina de Albacete, Universidad de Castilla-La Mancha, Albacete, Spain.; Instituto de Investigación en Discapacidades Neurológicas (IDINE), Universidad de Castilla-La Mancha, Albacete, Spain.; Cooperative Research Network on Age-Related Ocular Pathology, Visual and Life Quality (OFTARED), Instituto de Salud Carlos III, Madrid, Spain.
Atienzar-Aroca R; Área de Genética, Facultad de Medicina de Albacete, Universidad de Castilla-La Mancha, Albacete, Spain.; Instituto de Investigación en Discapacidades Neurológicas (IDINE), Universidad de Castilla-La Mancha, Albacete, Spain.; Cooperative Research Network on Age-Related Ocular Pathology, Visual and Life Quality (OFTARED), Instituto de Salud Carlos III, Madrid, Spain.
Villaverde C; Área de Genética and Genómica, Instituto de Investigación Sanitaria-Hospital Universitario Fundación Jiménez Díaz-Universidad Autónoma de Madrid (IIS-FJD, UAM), Madrid, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), Madrid, Spain.
Iancu I; Área de Genética and Genómica, Instituto de Investigación Sanitaria-Hospital Universitario Fundación Jiménez Díaz-Universidad Autónoma de Madrid (IIS-FJD, UAM), Madrid, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), Madrid, Spain.
Tamayo A; Área de Genética and Genómica, Instituto de Investigación Sanitaria-Hospital Universitario Fundación Jiménez Díaz-Universidad Autónoma de Madrid (IIS-FJD, UAM), Madrid, Spain.
Méndez-Hernández CD; Cooperative Research Network on Age-Related Ocular Pathology, Visual and Life Quality (OFTARED), Instituto de Salud Carlos III, Madrid, Spain.; Servicio de Oftalmología, Hospital San Carlos, Madrid, Spain.; Instituto de Investigación Sanitaria del Hospital Clínico San Carlos, Madrid, Spain.
Morales-Fernández L; Cooperative Research Network on Age-Related Ocular Pathology, Visual and Life Quality (OFTARED), Instituto de Salud Carlos III, Madrid, Spain.; Servicio de Oftalmología, Hospital San Carlos, Madrid, Spain.; Instituto de Investigación Sanitaria del Hospital Clínico San Carlos, Madrid, Spain.
Rojas B; Cooperative Research Network on Age-Related Ocular Pathology, Visual and Life Quality (OFTARED), Instituto de Salud Carlos III, Madrid, Spain.; Instituto de Investigaciones Oftalmológicas Ramón Castroviejo, Universidad Complutense de Madrid, Madrid, Spain.; Facultad de Medicina, Universidad Complutense de Madrid, Madrid, Spain.
Ayuso C; Área de Genética and Genómica, Instituto de Investigación Sanitaria-Hospital Universitario Fundación Jiménez Díaz-Universidad Autónoma de Madrid (IIS-FJD, UAM), Madrid, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), Madrid, Spain.
Coca-Prados M; Department of Ophthalmology and Visual Science, Yale University School of Medicine, New Haven, CT, USA.
Martinez-de-la-Casa JM; Cooperative Research Network on Age-Related Ocular Pathology, Visual and Life Quality (OFTARED), Instituto de Salud Carlos III, Madrid, Spain.; Servicio de Oftalmología, Hospital San Carlos, Madrid, Spain.; Instituto de Investigación Sanitaria del Hospital Clínico San Carlos, Madrid, Spain.
García-Feijoo J; Cooperative Research Network on Age-Related Ocular Pathology, Visual and Life Quality (OFTARED), Instituto de Salud Carlos III, Madrid, Spain.; Servicio de Oftalmología, Hospital San Carlos, Madrid, Spain.; Instituto de Investigación Sanitaria del Hospital Clínico San Carlos, Madrid, Spain.
Escribano J; Área de Genética, Facultad de Medicina de Albacete, Universidad de Castilla-La Mancha, Albacete, Spain. .; Instituto de Investigación en Discapacidades Neurológicas (IDINE), Universidad de Castilla-La Mancha, Albacete, Spain. .; Cooperative Research Network on Age-Related Ocular Pathology, Visual and Life Quality (OFTARED), Instituto de Salud Carlos III, Madrid, Spain. .
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Źródło :
Human genetics [Hum Genet] 2020 Oct; Vol. 139 (10), pp. 1209-1231. Date of Electronic Publication: 2020 Apr 09.
Typ publikacji :
Journal Article
MeSH Terms :
Loss of Function Mutation*
Complement C3/*genetics
Extracellular Matrix/*metabolism
Eye Abnormalities/*genetics
Glaucoma/*genetics
Trypsin Inhibitor, Kazal Pancreatic/*genetics
alpha-Macroglobulins/*genetics
Adult ; Animals ; Anterior Chamber/metabolism ; Anterior Chamber/pathology ; Anterior Chamber/surgery ; CRISPR-Cas Systems ; Case-Control Studies ; Complement C3/deficiency ; Embryo, Nonmammalian ; Extracellular Matrix/pathology ; Eye Abnormalities/metabolism ; Eye Abnormalities/pathology ; Eye Abnormalities/surgery ; Female ; Gene Editing ; Gene Expression ; Genes, Recessive ; Glaucoma/metabolism ; Glaucoma/pathology ; Glaucoma/surgery ; High-Throughput Nucleotide Sequencing ; Humans ; Male ; Middle Aged ; Pedigree ; Trabecular Meshwork/metabolism ; Trabecular Meshwork/pathology ; Trabecular Meshwork/surgery ; Trabeculectomy ; Trypsin Inhibitor, Kazal Pancreatic/deficiency ; Zebrafish ; alpha-Macroglobulins/deficiency
SCR Disease Name :
Anterior segment mesenchymal dysgenesis
Czasopismo naukowe
Tytuł :
Thrombospondin-2 is up-regulated by TGFβ2 and increases fibronectin expression in human trabecular meshwork cells.
Autorzy :
Kennedy SM; Department of Eye and Vision Science, Institute of Ageing and Chronic Disease, University of Liverpool, William Henry Duncan Building, 6 west Derby Street, Liverpool, L69 8TX, UK. Electronic address: .
Sheridan C; Department of Eye and Vision Science, Institute of Ageing and Chronic Disease, University of Liverpool, William Henry Duncan Building, 6 west Derby Street, Liverpool, L69 8TX, UK. Electronic address: .
Kearns VR; Department of Eye and Vision Science, Institute of Ageing and Chronic Disease, University of Liverpool, William Henry Duncan Building, 6 west Derby Street, Liverpool, L69 8TX, UK. Electronic address: .
Bilir EK; Department of Eye and Vision Science, Institute of Ageing and Chronic Disease, University of Liverpool, William Henry Duncan Building, 6 west Derby Street, Liverpool, L69 8TX, UK. Electronic address: .
Fan X; Department of Eye and Vision Science, Institute of Ageing and Chronic Disease, University of Liverpool, William Henry Duncan Building, 6 west Derby Street, Liverpool, L69 8TX, UK. Electronic address: .
Grierson I; Department of Eye and Vision Science, Institute of Ageing and Chronic Disease, University of Liverpool, William Henry Duncan Building, 6 west Derby Street, Liverpool, L69 8TX, UK. Electronic address: .
Choudhary A; Department of Eye and Vision Science, Institute of Ageing and Chronic Disease, University of Liverpool, William Henry Duncan Building, 6 west Derby Street, Liverpool, L69 8TX, UK; St Paul's Eye Unit, Royal Liverpool University Hospital, Liverpool, L7 8XP, UK. Electronic address: .
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Źródło :
Experimental eye research [Exp Eye Res] 2019 Dec; Vol. 189, pp. 107820. Date of Electronic Publication: 2019 Oct 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation*
Up-Regulation*
Fibronectins/*genetics
Glaucoma, Open-Angle/*genetics
Thrombospondins/*genetics
Trabecular Meshwork/*metabolism
Transforming Growth Factor beta2/*metabolism
Cell Adhesion Molecules ; Cells, Cultured ; Fibronectins/biosynthesis ; Glaucoma, Open-Angle/metabolism ; Glaucoma, Open-Angle/pathology ; Humans ; Intraocular Pressure/physiology ; RNA, Messenger/genetics ; Thrombospondins/biosynthesis ; Trabecular Meshwork/pathology
Czasopismo naukowe
Tytuł :
Salidroside mitigates hydrogen peroxide-induced injury by enhancement of microRNA-27a in human trabecular meshwork cells.
Autorzy :
Zhao J; a Department of Ophthalmology , Linyi People's Hospital , Linyi , China.
Du X; b Department of Ophthalmology, Eye Institute of Shandong University of Traditional Chinese Medicine , Affiliated Eye Hospital of Shandong University of TCM , Jinan , China.
Wang M; a Department of Ophthalmology , Linyi People's Hospital , Linyi , China.
Yang P; c Qingdao University , Qingdao , China.
Zhang J; a Department of Ophthalmology , Linyi People's Hospital , Linyi , China.
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Źródło :
Artificial cells, nanomedicine, and biotechnology [Artif Cells Nanomed Biotechnol] 2019 Dec; Vol. 47 (1), pp. 1758-1765.
Typ publikacji :
Journal Article
MeSH Terms :
Glucosides/*pharmacology
Hydrogen Peroxide/*pharmacology
MicroRNAs/*genetics
Phenols/*pharmacology
Trabecular Meshwork/*cytology
Trabecular Meshwork/*drug effects
Apoptosis/drug effects ; Cytoprotection/drug effects ; Gene Expression Regulation/drug effects ; Humans ; Oxidative Stress/drug effects ; Phosphatidylinositol 3-Kinases/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Trabecular Meshwork/metabolism ; Wnt Signaling Pathway/drug effects
Czasopismo naukowe
Tytuł :
Effect of intracameral human cord blood-derived stem cells on lasered rabbit trabecular meshwork.
Autorzy :
Sihota R; Glaucoma Research Facility and Clinical Services, Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, 110029, India. .
Sen S; Ocular Pathology, All India Institute of Medical Sciences, New Delhi, 110029, India.
Mohanty S; Stem Cell Facility, All India Institute of Medical Sciences, New Delhi, 110029, India.
Ahmad M; Ocular Pathology, All India Institute of Medical Sciences, New Delhi, 110029, India.
Ravi A; Glaucoma Research Facility and Clinical Services, Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, 110029, India.
Gupta V; Glaucoma Research Facility and Clinical Services, Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, 110029, India.
Bhatla N; Obstetrics and Gynaecology, All India Institute of Medical Sciences, New Delhi, 110029, India.
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Źródło :
International ophthalmology [Int Ophthalmol] 2019 Dec; Vol. 39 (12), pp. 2757-2766. Date of Electronic Publication: 2019 May 28.
Typ publikacji :
Journal Article
MeSH Terms :
Eye Injuries/*therapy
Fetal Blood/*cytology
Stem Cell Transplantation/*methods
Trabecular Meshwork/*injuries
Animals ; Humans ; Lasers/adverse effects ; Rabbits ; Trabecular Meshwork/pathology
Czasopismo naukowe
Tytuł :
Effects of TAK-639, a novel topical C-type natriuretic peptide analog, on intraocular pressure and aqueous humor dynamics in mice.
Autorzy :
Millar JC; North Texas Eye Research Institute, Department of Pharmacology & Neuroscience, University of North Texas Health Science Center, Fort Worth, TX, USA.
Savinainen A; Shire, a part of Takeda, Lexington, MA, USA.
Josiah S; Shire, a part of Takeda, Lexington, MA, USA.
Pang IH; North Texas Eye Research Institute, Department of Pharmacology & Neuroscience, University of North Texas Health Science Center, Fort Worth, TX, USA; Pharmaceutical Sciences, University of North Texas Health Science Center, Fort Worth, TX, USA. Electronic address: .
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Źródło :
Experimental eye research [Exp Eye Res] 2019 Nov; Vol. 188, pp. 107763. Date of Electronic Publication: 2019 Aug 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Aqueous Humor/*physiology
Intraocular Pressure/*drug effects
Natriuretic Peptide, C-Type/*analogs & derivatives
Natriuretic Peptide, C-Type/*pharmacology
Trabecular Meshwork/*drug effects
Administration, Ophthalmic ; Animals ; Cell Line, Transformed ; Cyclic GMP/metabolism ; Female ; Humans ; Mice ; Mice, Inbred C57BL ; Ophthalmic Solutions ; Receptor, Angiotensin, Type 2/metabolism ; Receptor, Cholecystokinin A/metabolism ; Receptors, Atrial Natriuretic Factor/metabolism ; Tonometry, Ocular ; Trabecular Meshwork/metabolism
Czasopismo naukowe
Tytuł :
Testing Species Assignments in Extant Terebratulide Brachiopods: A Three-dimensional Geometric Morphometric Analysis of Long-Looped Brachidia.
Autorzy :
López Carranza N; Department of Earth and Planetary Sciences, University of California, Davis, CA, United States of America.
Carlson SJ; Department of Earth and Planetary Sciences, University of California, Davis, CA, United States of America.
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Źródło :
PloS one [PLoS One] 2019 Nov 27; Vol. 14 (11), pp. e0225528. Date of Electronic Publication: 2019 Nov 27 (Print Publication: 2019).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Animal Shells/*anatomy & histology
Heart Valves/*anatomy & histology
Invertebrates/*anatomy & histology
Trabecular Meshwork/*anatomy & histology
Animal Shells/physiology ; Animals ; Heart Valves/physiology ; Invertebrates/physiology ; Trabecular Meshwork/physiology
Czasopismo naukowe
Tytuł :
Transcriptome analysis reveals autophagy as regulator of TGFβ/Smad-induced fibrogenesis in trabecular meshwork cells.
Autorzy :
Nettesheim A; Duke University, Department of Ophthalmology, Durham, NC, USA.
Shim MS; Duke University, Department of Ophthalmology, Durham, NC, USA.
Hirt J; Duke University, Department of Ophthalmology, Durham, NC, USA.
Liton PB; Duke University, Department of Ophthalmology, Durham, NC, USA. .
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Źródło :
Scientific reports [Sci Rep] 2019 Nov 06; Vol. 9 (1), pp. 16092. Date of Electronic Publication: 2019 Nov 06.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Autophagy*
Fibrosis/*metabolism
Smad2 Protein/*metabolism
Smad3 Protein/*metabolism
Trabecular Meshwork/*cytology
Transforming Growth Factor beta2/*metabolism
Autophagy-Related Protein 5/genetics ; Autophagy-Related Protein 5/metabolism ; Autophagy-Related Protein 7/genetics ; Autophagy-Related Protein 7/metabolism ; Cells, Cultured ; Fibrosis/genetics ; Fibrosis/physiopathology ; Humans ; Membrane Proteins/genetics ; Membrane Proteins/metabolism ; Smad2 Protein/genetics ; Smad3 Protein/genetics ; Trabecular Meshwork/metabolism
Czasopismo naukowe
Tytuł :
Phenotypic and Functional Alterations in Tunneling Nanotubes Formed by Glaucomatous Trabecular Meshwork Cells.
Autorzy :
Sun YY; Casey Eye Institute, Oregon Health & Science University, Portland, Oregon, United States.
Bradley JM; Casey Eye Institute, Oregon Health & Science University, Portland, Oregon, United States.
Keller KE; Casey Eye Institute, Oregon Health & Science University, Portland, Oregon, United States.
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Źródło :
Investigative ophthalmology & visual science [Invest Ophthalmol Vis Sci] 2019 Nov 01; Vol. 60 (14), pp. 4583-4595.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Nanotubes*
Actin Cytoskeleton/*metabolism
Glaucoma, Open-Angle/*pathology
Myosins/*metabolism
Pseudopodia/*metabolism
Trabecular Meshwork/*pathology
Blotting, Western ; Cell Size ; Cells, Cultured ; Cellular Senescence/physiology ; Densitometry ; Glaucoma, Open-Angle/metabolism ; Humans ; Microscopy, Confocal ; Phagocytosis/physiology ; Phenotype ; Signal Transduction/physiology ; Trabecular Meshwork/metabolism
Czasopismo naukowe
Tytuł :
Trabecular meshwork mesenchymal stem cell transplantation improve motor symptoms of parkinsonian rat model.
Autorzy :
Mostafavi H; Department of Physiology, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran; Department of Medical Nanotechnology, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran.
Ghassemifard L; Department of Physiology, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran.
Rostami A; Department of Physiology, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran.
Alipour M; Department of Physiology, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran.
Nadri S; Department of Medical Nanotechnology, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran; Zanjan Metabolic Diseases Research Center, Zanjan University of Medical Sciences, Zanjan, Iran; Cancer Gene Therapy Research Center, Zanjan University of Medical Sciences, Zanjan, Iran; Zanjan Pharmaceutical Nanotechnology Research Center, Zanjan University of Medical Sciences, Zanjan, Iran. Electronic address: .
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Źródło :
Biologicals : journal of the International Association of Biological Standardization [Biologicals] 2019 Sep; Vol. 61, pp. 61-67. Date of Electronic Publication: 2019 Jun 29.
Typ publikacji :
Journal Article
MeSH Terms :
Mesenchymal Stem Cell Transplantation*
Mesenchymal Stem Cells*/metabolism
Mesenchymal Stem Cells*/pathology
Motor Activity*
Parkinson Disease, Secondary*/metabolism
Parkinson Disease, Secondary*/pathology
Parkinson Disease, Secondary*/therapy
Trabecular Meshwork*/metabolism
Trabecular Meshwork*/pathology
Allografts ; Animals ; Disease Models, Animal ; Male ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Prion protein modulates endothelial to mesenchyme-like transition in trabecular meshwork cells: Implications for primary open angle glaucoma.
Autorzy :
Ashok A; Department of Pathology, School of Medicine, Case Western Reserve University, Cleveland, Ohio, 44106, USA.
Kang MH; Department of Ophthalmology, School of Medicine, Case Western Reserve University, Cleveland, Ohio, 44106, USA.
Wise AS; Department of Pathology, School of Medicine, Case Western Reserve University, Cleveland, Ohio, 44106, USA.
Pattabiraman P; Department of Ophthalmology, School of Medicine, Case Western Reserve University, Cleveland, Ohio, 44106, USA.
Johnson WM; Department of Ophthalmology, Duke University, Durham, NC, USA.
Lonigro M; Department of Pathology, School of Medicine, Case Western Reserve University, Cleveland, Ohio, 44106, USA.
Ravikumar R; Department of Pathology, School of Medicine, Case Western Reserve University, Cleveland, Ohio, 44106, USA.
Rhee DJ; Department of Ophthalmology, School of Medicine, Case Western Reserve University, Cleveland, Ohio, 44106, USA.
Singh N; Department of Pathology, School of Medicine, Case Western Reserve University, Cleveland, Ohio, 44106, USA. .
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Źródło :
Scientific reports [Sci Rep] 2019 Sep 11; Vol. 9 (1), pp. 13090. Date of Electronic Publication: 2019 Sep 11.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Endothelial Cells/*cytology
Glaucoma, Open-Angle/*metabolism
Glaucoma, Open-Angle/*pathology
Mesoderm/*cytology
PrPC Proteins/*metabolism
Trabecular Meshwork/*cytology
Animals ; Cattle ; Endothelial Cells/pathology ; Gene Expression Regulation ; Gene Silencing ; Humans ; Mesoderm/pathology ; Mice ; PrPC Proteins/deficiency ; PrPC Proteins/genetics ; Trabecular Meshwork/metabolism ; Trabecular Meshwork/pathology
Czasopismo naukowe
Tytuł :
2D- and 3D-cultures of human trabecular meshwork cells: A preliminary assessment of an in vitro model for glaucoma study.
Autorzy :
Vernazza S; IRCCS, Fondazione G.B. Bietti, Rome, Italy.
Tirendi S; Department of Experimental Medicine (DIMES), University of Genoa, Genoa, Italy.; Inter-University Center for the Promotion of the 3Rs Principles in Teaching & Research (Centro 3R), Italy.
Scarfì S; Inter-University Center for the Promotion of the 3Rs Principles in Teaching & Research (Centro 3R), Italy.; Department of Earth, Environment and Life Sciences (DISTAV), University of Genoa, Genoa, Italy.
Passalacqua M; Department of Experimental Medicine (DIMES), University of Genoa, Genoa, Italy.; Inter-University Center for the Promotion of the 3Rs Principles in Teaching & Research (Centro 3R), Italy.
Oddone F; IRCCS, Fondazione G.B. Bietti, Rome, Italy.
Traverso CE; Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI), University of Genoa, Genoa, Italy.
Rizzato I; Inter-University Center for the Promotion of the 3Rs Principles in Teaching & Research (Centro 3R), Italy.; Department of Modern Languages and Cultures (LCM), University of Genoa, Genoa, Italy.
Bassi AM; Department of Experimental Medicine (DIMES), University of Genoa, Genoa, Italy.; Inter-University Center for the Promotion of the 3Rs Principles in Teaching & Research (Centro 3R), Italy.
Saccà SC; IRCCS, San Martino General Hospital, Ophthalmology Unit, Genoa, Italy.
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Źródło :
PloS one [PLoS One] 2019 Sep 06; Vol. 14 (9), pp. e0221942. Date of Electronic Publication: 2019 Sep 06 (Print Publication: 2019).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Glaucoma/*pathology
Trabecular Meshwork/*cytology
Apoptosis/drug effects ; Cell Culture Techniques ; Cell Respiration/drug effects ; Cytokines/metabolism ; Gene Expression Regulation/drug effects ; Humans ; Hydrogen Peroxide/pharmacology ; Mitochondria/drug effects ; Mitochondria/metabolism ; NF-kappa B/genetics ; Oxidative Stress/drug effects ; Reactive Oxygen Species/metabolism ; Trabecular Meshwork/drug effects ; Trabecular Meshwork/metabolism ; Transcriptional Activation/drug effects
Czasopismo naukowe

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