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Tytuł :
O-GlcNAc modification regulates MTA1 transcriptional activity during breast cancer cell genotoxic adaptation.
Autorzy :
Xie X; School of Life and Pharmaceutical Sciences, Dalian University of Technology, Panjin, China.
Wu Q; School of Life and Pharmaceutical Sciences, Dalian University of Technology, Panjin, China.
Zhang K; Clinical Laboratory of BGI Health, BGI-Shenzhen, Shenzhen, China.
Liu Y; School of Life and Pharmaceutical Sciences, Dalian University of Technology, Panjin, China.
Zhang N; School of Life and Pharmaceutical Sciences, Dalian University of Technology, Panjin, China.
Chen Q; Clinical Laboratory of BGI Health, BGI-Shenzhen, Shenzhen, China.
Wang L; School of Life and Pharmaceutical Sciences, Dalian University of Technology, Panjin, China.
Li W; School of Life and Pharmaceutical Sciences, Dalian University of Technology, Panjin, China.
Zhang J; School of Life and Pharmaceutical Sciences, Dalian University of Technology, Panjin, China.. Electronic address: .
Liu Y; School of Life and Pharmaceutical Sciences, Dalian University of Technology, Panjin, China.. Electronic address: .
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Źródło :
Biochimica et biophysica acta. General subjects [Biochim Biophys Acta Gen Subj] 2021 Aug; Vol. 1865 (8), pp. 129930. Date of Electronic Publication: 2021 May 18.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA Damage*
Gene Expression Regulation, Neoplastic*
Protein Processing, Post-Translational*
Acetylglucosamine/*chemistry
Biomarkers, Tumor/*metabolism
Breast Neoplasms/*pathology
Repressor Proteins/*metabolism
Trans-Activators/*metabolism
Acetylglucosamine/metabolism ; Apoptosis ; Biomarkers, Tumor/genetics ; Breast Neoplasms/genetics ; Breast Neoplasms/metabolism ; Cell Proliferation ; Chromatin/chemistry ; Chromatin/genetics ; Chromatin/metabolism ; Gene Expression Profiling ; Humans ; N-Acetylglucosaminyltransferases/metabolism ; Prognosis ; Repressor Proteins/chemistry ; Repressor Proteins/genetics ; Survival Rate ; Trans-Activators/chemistry ; Trans-Activators/genetics ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł :
MYBL2 in synergy with CDC20 promotes the proliferation and inhibits apoptosis of gastric cancer cells.
Autorzy :
Deng Q; Department of Gastroenterology, The Third Hospital of Mianyang, Sichuan Mental Health Center, China.
Wu L; Department of Anesthesiology, The Third Hospital of Mianyang, Sichuan Mental Health Center, China.
Li Y; Department of Gastroenterology, The Third Hospital of Mianyang, Sichuan Mental Health Center, China.
Zou L; Department of Gastroenterology, The Third Hospital of Mianyang, Sichuan Mental Health Center, China.
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Źródło :
Advances in clinical and experimental medicine : official organ Wroclaw Medical University [Adv Clin Exp Med] 2021 Sep; Vol. 30 (9), pp. 957-966.
Typ publikacji :
Journal Article
MeSH Terms :
Cdc20 Proteins*/genetics
Cell Cycle Proteins*/genetics
Stomach Neoplasms*/genetics
Trans-Activators*/genetics
Apoptosis ; Cell Line, Tumor ; Cell Proliferation ; Humans ; Wnt Signaling Pathway
Czasopismo naukowe
Tytuł :
AtMYB32 regulates the ABA response by targeting ABI3, ABI4 and ABI5 and the drought response by targeting CBF4 in Arabidopsis.
Autorzy :
Li X; College of Biology, Hunan Province Key Laboratory of Plant Functional Genomics and Developmental Regulation, Hunan Hybrid Rape Engineering and Technology Research Center, Hunan University, Changsha, 410082, China; Shenzhen Institute, Hunan University, Shenzhen, 518057, China.
Zhong M; College of Biology, Hunan Province Key Laboratory of Plant Functional Genomics and Developmental Regulation, Hunan Hybrid Rape Engineering and Technology Research Center, Hunan University, Changsha, 410082, China; Shenzhen Institute, Hunan University, Shenzhen, 518057, China.
Qu L; College of Biology, Hunan Province Key Laboratory of Plant Functional Genomics and Developmental Regulation, Hunan Hybrid Rape Engineering and Technology Research Center, Hunan University, Changsha, 410082, China; Shenzhen Institute, Hunan University, Shenzhen, 518057, China.
Yang J; College of Biology, Hunan Province Key Laboratory of Plant Functional Genomics and Developmental Regulation, Hunan Hybrid Rape Engineering and Technology Research Center, Hunan University, Changsha, 410082, China; Shenzhen Institute, Hunan University, Shenzhen, 518057, China.
Liu X; College of Biology, Hunan Province Key Laboratory of Plant Functional Genomics and Developmental Regulation, Hunan Hybrid Rape Engineering and Technology Research Center, Hunan University, Changsha, 410082, China.
Zhao Q; College of Biology, Hunan Province Key Laboratory of Plant Functional Genomics and Developmental Regulation, Hunan Hybrid Rape Engineering and Technology Research Center, Hunan University, Changsha, 410082, China.
Liu X; College of Biology, Hunan Province Key Laboratory of Plant Functional Genomics and Developmental Regulation, Hunan Hybrid Rape Engineering and Technology Research Center, Hunan University, Changsha, 410082, China. Electronic address: .
Zhao X; College of Biology, Hunan Province Key Laboratory of Plant Functional Genomics and Developmental Regulation, Hunan Hybrid Rape Engineering and Technology Research Center, Hunan University, Changsha, 410082, China; Shenzhen Institute, Hunan University, Shenzhen, 518057, China. Electronic address: .
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Źródło :
Plant science : an international journal of experimental plant biology [Plant Sci] 2021 Sep; Vol. 310, pp. 110983. Date of Electronic Publication: 2021 Jun 21.
Typ publikacji :
Journal Article
MeSH Terms :
Abscisic Acid/*pharmacology
Arabidopsis/*drug effects
Arabidopsis/*metabolism
Arabidopsis Proteins/*metabolism
Basic-Leucine Zipper Transcription Factors/*metabolism
Trans-Activators/*metabolism
Transcription Factors/*metabolism
Arabidopsis Proteins/drug effects ; Arabidopsis Proteins/genetics ; Basic-Leucine Zipper Transcription Factors/drug effects ; Droughts ; Gene Expression Regulation, Plant/drug effects ; Gene Expression Regulation, Plant/genetics ; Trans-Activators/drug effects ; Transcription Factors/drug effects
Czasopismo naukowe
Tytuł :
Genetic analysis of primary open-angle glaucoma-related risk alleles in a Korean population: the GLAU-GENDISK study.
Autorzy :
Kim YW; Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea.; Department of Ophthalmology, Seoul National University Hospital, Seoul, Korea.
Lee YH; Department of Public Health Sciences, Seoul National University, Seoul, Korea.
Kim JS; Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea.; Department of Ophthalmology, Chungnam National University Sejong Hospital, Sejong, Korea.
Lee J; Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea.; Department of Ophthalmology, Hallym University Chuncheon Sacred Heart Hospital, Chuncheon, Korea.
Kim YJ; Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea.
Cheong HS; Department of Genetic Epidemiology, SNP Genetics, Inc., Seoul, Korea.
Kim SH; Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea.; Department of Ophthalmology, Seoul National University Boramae Medical Center, Seoul, Korea.
Park KH; Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea.; Department of Ophthalmology, Seoul National University Hospital, Seoul, Korea.
Kim DM; Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea.
Choi HJ; Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea.; Seoul National University Hospital Healthcare System Gangnam Center, Seoul, Korea.
Jeoung JW; Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea .; Department of Ophthalmology, Seoul National University Hospital, Seoul, Korea.
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Źródło :
The British journal of ophthalmology [Br J Ophthalmol] 2021 Sep; Vol. 105 (9), pp. 1307-1312. Date of Electronic Publication: 2020 Sep 15.
Typ publikacji :
Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
MeSH Terms :
Genetic Predisposition to Disease*
Polymorphism, Single Nucleotide*
DNA/*genetics
Glaucoma, Open-Angle/*genetics
Homeodomain Proteins/*genetics
Intraocular Pressure/*physiology
Trans-Activators/*genetics
Alleles ; Female ; Follow-Up Studies ; Genotype ; Glaucoma, Open-Angle/epidemiology ; Glaucoma, Open-Angle/physiopathology ; Homeodomain Proteins/metabolism ; Humans ; Incidence ; Male ; Middle Aged ; Prospective Studies ; Republic of Korea/epidemiology ; Trans-Activators/metabolism
Czasopismo naukowe
Tytuł :
Molecular Mechanisms and Animal Models of HBV-Related Hepatocellular Carcinoma: With Emphasis on Metastatic Tumor Antigen 1.
Autorzy :
Li YT; Department of Internal Medicine, College of Medicine, National Taiwan University, Taipei 100, Taiwan.; Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei 100, Taiwan.; Hepatitis Research Center, National Taiwan University Hospital, Taipei 100, Taiwan.
Wu HL; Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei 100, Taiwan.; Hepatitis Research Center, National Taiwan University Hospital, Taipei 100, Taiwan.
Liu CJ; Department of Internal Medicine, College of Medicine, National Taiwan University, Taipei 100, Taiwan.; Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei 100, Taiwan.; Hepatitis Research Center, National Taiwan University Hospital, Taipei 100, Taiwan.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Aug 29; Vol. 22 (17). Date of Electronic Publication: 2021 Aug 29.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Carcinoma, Hepatocellular/*virology
Hepatitis B/*pathology
Liver Neoplasms/*virology
Repressor Proteins/*metabolism
Trans-Activators/*metabolism
Animals ; Carcinoma, Hepatocellular/pathology ; Hepatitis B/complications ; Hepatitis B virus/genetics ; Hepatitis B virus/pathogenicity ; Humans ; Liver Neoplasms/pathology ; Liver Neoplasms, Experimental/virology ; Marmota ; Mice ; Mice, Transgenic ; Repressor Proteins/chemistry ; Trans-Activators/chemistry
Czasopismo naukowe
Tytuł :
The Role of Mutant p63 in Female Fertility.
Autorzy :
Luan Y; Department of Obstetrics and Gynecology, Olson Center for Women's Health, College of Medicine, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Xu P; Department of Obstetrics and Gynecology, Olson Center for Women's Health, College of Medicine, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Yu SY; Department of Obstetrics and Gynecology, Olson Center for Women's Health, College of Medicine, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Kim SY; Department of Obstetrics and Gynecology, Olson Center for Women's Health, College of Medicine, University of Nebraska Medical Center, Omaha, NE 68198, USA.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Aug 20; Vol. 22 (16). Date of Electronic Publication: 2021 Aug 20.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Fertility/*genetics
Trans-Activators/*genetics
Transcription Factors/*genetics
Tumor Suppressor Proteins/*genetics
Alternative Splicing/genetics ; Animals ; Cell Nucleus/metabolism ; Female ; Genes, p53/genetics ; Humans ; Mice ; Mutation/genetics ; Oocytes/metabolism ; Ovary/metabolism ; Primary Ovarian Insufficiency/metabolism ; Protein Isoforms/metabolism ; Trans-Activators/metabolism ; Transcription Factors/metabolism ; Tumor Suppressor Proteins/metabolism
Czasopismo naukowe
Tytuł :
HLA-DRB1 genes and the expression dynamics of HLA CIITA determine the susceptibility to T2DM.
Autorzy :
Chinniah R; Department of Immunology, School of Biological Sciences, Madurai, Tamil Nadu, 625021, India.
Sevak V; Department of Immunology, School of Biological Sciences, Madurai, Tamil Nadu, 625021, India.
Pandi S; Department of Immunology, School of Biological Sciences, Madurai, Tamil Nadu, 625021, India.
Ravi PM; Department of Immunology, School of Biological Sciences, Madurai, Tamil Nadu, 625021, India.
Vijayan M; Department of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock, TX, 79430, USA.
Kannan A; The Madurai Institute of Diabetes and Endocrine Practice Research, Madurai, Tamil Nadu, 625 001, India.
Karuppiah B; Department of Immunology, School of Biological Sciences, Madurai, Tamil Nadu, 625021, India. .
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Źródło :
Immunogenetics [Immunogenetics] 2021 Aug; Vol. 73 (4), pp. 291-305. Date of Electronic Publication: 2021 Mar 22.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Genetic Predisposition to Disease*
Polymorphism, Single Nucleotide*
Diabetes Mellitus, Type 2/*pathology
HLA-DRB1 Chains/*genetics
Nuclear Proteins/*metabolism
Trans-Activators/*metabolism
Adult ; Case-Control Studies ; Diabetes Mellitus, Type 2/epidemiology ; Diabetes Mellitus, Type 2/genetics ; Female ; Humans ; Male ; Middle Aged ; Nuclear Proteins/genetics ; Trans-Activators/genetics
Czasopismo naukowe
Tytuł :
Role of Yes-associated protein and transcriptional coactivator with PDZ-binding motif in the malignant transformation of oral submucous fibrosis.
Autorzy :
Sharma M; Department of Oral Pathology, Sudha Rustagi College of Dental Sciences and Research, Faridabad, India.
Hunter KD; Academic Unit of Oral and Maxillofacial Medicine and Pathology, School of Clinical Dentistry, University of Sheffield, S10 2TA, United Kingdom.
Fonseca FP; Department of Oral Pathology and Surgery, School of Dentistry, Universidade Federal De Minas Gerais, Belo Horizonte, MG, 31270-901, Brazil.
Shetty SS; Department of Oral Pathology, Faculty of Dentistry, Melaka Manipal Medical College, Manipal Academy of Higher Education, Manipal, India.
Radhakrishnan R; Department of Oral Pathology, Manipal College of Dental Sciences, Manipal Academy of Higher Education, Manipal, 576104, India. Electronic address: .
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Źródło :
Archives of oral biology [Arch Oral Biol] 2021 Aug; Vol. 128, pp. 105164. Date of Electronic Publication: 2021 May 23.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Oral Submucous Fibrosis*
Trans-Activators*
Cell Movement ; Epithelial-Mesenchymal Transition ; Fibrosis ; Humans
Czasopismo naukowe
Tytuł :
Purine-rich element binding protein B attenuates the coactivator function of myocardin by a novel molecular mechanism of smooth muscle gene repression.
Autorzy :
Ferris LA; Department of Biochemistry, University of Vermont, Robert Larner, M.D. College of Medicine, Burlington, VT, 05405, USA.; Woodstock Union High School, 100 Amsden Way, Woodstock, VT, 05091, USA.
Foote AT; Department of Medicine, University of Vermont, Robert Larner, M.D. College of Medicine, Burlington, VT, 05405, USA.; Division of Cardiovascular Medicine, University of Vermont, Robert Larner, M.D. College of Medicine, Burlington, VT, 05405, USA.
Wang SX; Department of Medicine, University of Vermont, Robert Larner, M.D. College of Medicine, Burlington, VT, 05405, USA.; Division of Cardiovascular Medicine, University of Vermont, Robert Larner, M.D. College of Medicine, Burlington, VT, 05405, USA.
Kelm RJ Jr; Department of Biochemistry, University of Vermont, Robert Larner, M.D. College of Medicine, Burlington, VT, 05405, USA. .; Department of Medicine, University of Vermont, Robert Larner, M.D. College of Medicine, Burlington, VT, 05405, USA. .; Division of Cardiovascular Medicine, University of Vermont, Robert Larner, M.D. College of Medicine, Burlington, VT, 05405, USA. .; Department of Medicine, University of Vermont, Colchester Research Facility, 360 South Park Drive, Colchester, VT, 05446, USA. .
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Źródło :
Molecular and cellular biochemistry [Mol Cell Biochem] 2021 Aug; Vol. 476 (8), pp. 2899-2916. Date of Electronic Publication: 2021 Mar 20.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Differentiation*
Gene Expression Regulation*
DNA-Binding Proteins/*metabolism
Muscle Proteins/*metabolism
Muscle, Smooth/*cytology
Nuclear Proteins/*metabolism
Trans-Activators/*metabolism
Actins/genetics ; Actins/metabolism ; Animals ; DNA-Binding Proteins/genetics ; HEK293 Cells ; Humans ; Mice ; Mice, Inbred C57BL ; Muscle Proteins/genetics ; Muscle, Smooth/metabolism ; Nuclear Proteins/genetics ; Promoter Regions, Genetic ; Protein Binding ; Purines/metabolism ; Rats ; Trans-Activators/genetics
Czasopismo naukowe
Tytuł :
Senescence-Associated Glycine max ( Gm ) NAC Genes: Integration of Natural and Stress-Induced Leaf Senescence.
Autorzy :
Fraga OT; Biochemistry and Molecular Biology Department, Universidade Federal de Viçosa, Viçosa 36570.000, MG, Brazil.; National Institute of Science and Technology in Plant-Pest Interactions, INCTIPP-BIOAGRO, Universidade Federal de Viçosa, Viçosa 36570.000, MG, Brazil.
de Melo BP; Biochemistry and Molecular Biology Department, Universidade Federal de Viçosa, Viçosa 36570.000, MG, Brazil.; Embrapa Genetic Resources and Biotechnology, Brasília 70770.917, DF, Brazil.
Quadros IPS; Biochemistry and Molecular Biology Department, Universidade Federal de Viçosa, Viçosa 36570.000, MG, Brazil.; National Institute of Science and Technology in Plant-Pest Interactions, INCTIPP-BIOAGRO, Universidade Federal de Viçosa, Viçosa 36570.000, MG, Brazil.
Reis PAB; Biochemistry and Molecular Biology Department, Universidade Federal de Viçosa, Viçosa 36570.000, MG, Brazil.; National Institute of Science and Technology in Plant-Pest Interactions, INCTIPP-BIOAGRO, Universidade Federal de Viçosa, Viçosa 36570.000, MG, Brazil.
Fontes EPB; Biochemistry and Molecular Biology Department, Universidade Federal de Viçosa, Viçosa 36570.000, MG, Brazil.; National Institute of Science and Technology in Plant-Pest Interactions, INCTIPP-BIOAGRO, Universidade Federal de Viçosa, Viçosa 36570.000, MG, Brazil.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Aug 01; Vol. 22 (15). Date of Electronic Publication: 2021 Aug 01.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Cellular Senescence*
Gene Regulatory Networks*
Stress, Physiological*
Plant Leaves/*physiology
Plant Proteins/*metabolism
Soybeans/*physiology
Trans-Activators/*metabolism
Plant Proteins/genetics ; Trans-Activators/genetics
Czasopismo naukowe
Tytuł :
Analyzing the impact of CFP1 mutational landscape on epigenetic signaling.
Autorzy :
Yang Y; Ottawa Institute of Systems Biology, University of Ottawa, Ottawa, ON, Canada.; Shanghai Institute of Materia Medica-University of Ottawa Research Center in Systems and Personalized Pharmacology, University of Ottawa, Ottawa, ON, Canada.; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada.
Yang Y; Ottawa Institute of Systems Biology, University of Ottawa, Ottawa, ON, Canada.; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada.
Chan K; Ottawa Institute of Systems Biology, University of Ottawa, Ottawa, ON, Canada.; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada.
Couture JF; Ottawa Institute of Systems Biology, University of Ottawa, Ottawa, ON, Canada.; Shanghai Institute of Materia Medica-University of Ottawa Research Center in Systems and Personalized Pharmacology, University of Ottawa, Ottawa, ON, Canada.; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada.
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Źródło :
FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2021 Aug; Vol. 35 (8), pp. e21790.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Epigenesis, Genetic*
Mutation*
Neoplasms/*metabolism
Trans-Activators/*metabolism
Animals ; Gene Expression Regulation, Neoplastic ; Humans ; Trans-Activators/genetics
Czasopismo naukowe
Tytuł :
Smart-watch-programmed green-light-operated percutaneous control of therapeutic transgenes.
Autorzy :
Mansouri M; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland.
Hussherr MD; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland.
Strittmatter T; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland.
Buchmann P; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland.
Xue S; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland.
Camenisch G; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland.
Fussenegger M; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland. .; Faculty of Science, University of Basel, Basel, Switzerland. .
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Źródło :
Nature communications [Nat Commun] 2021 Jun 07; Vol. 12 (1), pp. 3388. Date of Electronic Publication: 2021 Jun 07.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Bacterial Proteins/*radiation effects
Diabetes Mellitus, Type 2/*therapy
Glucagon-Like Peptide 1/*therapeutic use
Optogenetics/*methods
Trans-Activators/*radiation effects
Animals ; Bacterial Proteins/genetics ; Bacterial Proteins/metabolism ; Cell Engineering ; Diabetes Mellitus, Type 2/genetics ; Female ; Genetic Engineering ; Glucagon-Like Peptide 1/genetics ; Glucagon-Like Peptide 1/metabolism ; HEK293 Cells ; Humans ; Light ; Male ; Mesenchymal Stem Cells ; Mice ; Mice, Obese ; Optogenetics/instrumentation ; Photoplethysmography/instrumentation ; Protein Domains/genetics ; Recombinant Fusion Proteins/genetics ; Recombinant Fusion Proteins/metabolism ; Recombinant Fusion Proteins/radiation effects ; Thermus thermophilus/genetics ; Trans-Activators/genetics ; Trans-Activators/metabolism ; Transgenes ; Wearable Electronic Devices
Czasopismo naukowe
Tytuł :
B Lymphocyte Specification Is Preceded by Extensive Epigenetic Priming in Multipotent Progenitors.
Autorzy :
Strid T; Department of Biological and Clinical Sciences, Linköping University, Linköping, Sweden.; Division of Molecular Hematology, Lund University, Lund, Sweden; and.; Department of Clinical Pathology, Biological and Clinical Sciences, Linköping University, Linköping, Sweden.
Okuyama K; Department of Biological and Clinical Sciences, Linköping University, Linköping, Sweden.
Tingvall-Gustafsson J; Division of Molecular Hematology, Lund University, Lund, Sweden; and.
Kuruvilla J; Division of Molecular Hematology, Lund University, Lund, Sweden; and.
Jensen CT; Division of Molecular Hematology, Lund University, Lund, Sweden; and.
Lang S; Division of Molecular Hematology, Lund University, Lund, Sweden; and.
Prasad M; Department of Biological and Clinical Sciences, Linköping University, Linköping, Sweden.
Somasundaram R; Department of Biological and Clinical Sciences, Linköping University, Linköping, Sweden.
Åhsberg J; Department of Biological and Clinical Sciences, Linköping University, Linköping, Sweden.
Cristobal S; Department of Biological and Clinical Sciences, Linköping University, Linköping, Sweden.
Soneji S; Division of Molecular Hematology, Lund University, Lund, Sweden; and.
Ungerbäck J; Division of Molecular Hematology, Lund University, Lund, Sweden; and.
Sigvardsson M; Department of Biological and Clinical Sciences, Linköping University, Linköping, Sweden; .; Division of Molecular Hematology, Lund University, Lund, Sweden; and.
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Źródło :
Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2021 Jun 01; Vol. 206 (11), pp. 2700-2713. Date of Electronic Publication: 2021 May 21.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
B-Lymphocytes/*immunology
Epigenesis, Genetic/*immunology
PAX5 Transcription Factor/*immunology
Trans-Activators/*immunology
Animals ; Epigenesis, Genetic/genetics ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; PAX5 Transcription Factor/deficiency ; PAX5 Transcription Factor/genetics ; Trans-Activators/deficiency ; Trans-Activators/genetics
Czasopismo naukowe
Tytuł :
The small-molecule protein ligand interface stabiliser E7820 induces differential cell line specific responses of integrin α2 expression.
Autorzy :
Hülskamp MD; Department of Regenerative Musculoskeletal Medicine, Institute for Musculoskeletal Medicine, Westfälische Wilhelms-Universität Münster, Albert-Schweitzer Campus 1 Building W1, 48149, Münster, Germany.
Kronenberg D; Department of Regenerative Musculoskeletal Medicine, Institute for Musculoskeletal Medicine, Westfälische Wilhelms-Universität Münster, Albert-Schweitzer Campus 1 Building W1, 48149, Münster, Germany. .
Stange R; Department of Regenerative Musculoskeletal Medicine, Institute for Musculoskeletal Medicine, Westfälische Wilhelms-Universität Münster, Albert-Schweitzer Campus 1 Building W1, 48149, Münster, Germany.
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Źródło :
BMC cancer [BMC Cancer] 2021 May 18; Vol. 21 (1), pp. 571. Date of Electronic Publication: 2021 May 18.
Typ publikacji :
Journal Article
MeSH Terms :
Indoles/*pharmacology
Integrin alpha2/*genetics
RNA-Binding Proteins/*antagonists & inhibitors
Sulfonamides/*pharmacology
Trans-Activators/*antagonists & inhibitors
Animals ; Cell Line ; Human Umbilical Vein Endothelial Cells/drug effects ; Human Umbilical Vein Endothelial Cells/metabolism ; Humans ; Integrin alpha2/metabolism ; Ligands ; Mice ; Osteoblasts/drug effects ; Osteoblasts/metabolism ; Promoter Regions, Genetic/genetics ; Protein Isoforms/antagonists & inhibitors ; Protein Isoforms/genetics ; Protein Isoforms/metabolism ; Proteolysis/drug effects ; RNA-Binding Proteins/genetics ; RNA-Binding Proteins/metabolism ; Trans-Activators/genetics ; Trans-Activators/metabolism ; Up-Regulation/drug effects
Czasopismo naukowe
Tytuł :
Targeting hyperactive TGFBR2 for treating MYOCD deficient lung cancer.
Autorzy :
Zhou Q; MOE Key Laboratory of Tumor Molecular Biology and Key Laboratory of Functional Protein Research of Guangdong Higher Education Institutes, Institute of Life and Health Engineering, College of Life Science and Technology, Jinan University, Guangzhou 510632, China.
Chen W; MOE Key Laboratory of Tumor Molecular Biology and Key Laboratory of Functional Protein Research of Guangdong Higher Education Institutes, Institute of Life and Health Engineering, College of Life Science and Technology, Jinan University, Guangzhou 510632, China.
Fan Z; MOE Key Laboratory of Tumor Molecular Biology and Key Laboratory of Functional Protein Research of Guangdong Higher Education Institutes, Institute of Life and Health Engineering, College of Life Science and Technology, Jinan University, Guangzhou 510632, China.
Chen Z; MOE Key Laboratory of Tumor Molecular Biology and Key Laboratory of Functional Protein Research of Guangdong Higher Education Institutes, Institute of Life and Health Engineering, College of Life Science and Technology, Jinan University, Guangzhou 510632, China.
Liang J; MOE Key Laboratory of Tumor Molecular Biology and Key Laboratory of Functional Protein Research of Guangdong Higher Education Institutes, Institute of Life and Health Engineering, College of Life Science and Technology, Jinan University, Guangzhou 510632, China.
Zeng G; MOE Key Laboratory of Tumor Molecular Biology and Key Laboratory of Functional Protein Research of Guangdong Higher Education Institutes, Institute of Life and Health Engineering, College of Life Science and Technology, Jinan University, Guangzhou 510632, China.
Liu L; MOE Key Laboratory of Tumor Molecular Biology and Key Laboratory of Functional Protein Research of Guangdong Higher Education Institutes, Institute of Life and Health Engineering, College of Life Science and Technology, Jinan University, Guangzhou 510632, China.
Liu W; MOE Key Laboratory of Tumor Molecular Biology and Key Laboratory of Functional Protein Research of Guangdong Higher Education Institutes, Institute of Life and Health Engineering, College of Life Science and Technology, Jinan University, Guangzhou 510632, China.
Yang T; MOE Key Laboratory of Tumor Molecular Biology and Key Laboratory of Functional Protein Research of Guangdong Higher Education Institutes, Institute of Life and Health Engineering, College of Life Science and Technology, Jinan University, Guangzhou 510632, China.
Cao X; Zhongshan Hospital, Institute of Clinical Science, Fudan University Shanghai Medical College, 180 Fengling Road, Shanghai, 200032, China.
Yu B; State Key Laboratory of Bioorganic and Natural Products Chemistry, Center for Excellence in Molecular Synthesis, Shanghai, Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 345 Lingling Road, Shanghai, 200032, China.
Xu M; Department of Oncology, The First Affiliated Hospital, Jinan University, Guangzhou 510632, China.
Chen YG; The State Key Laboratory of Membrane Biology, Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China.; Max-Planck Center for Tissue Stem Cell Research and Regenerative Medicine, Guangzhou Regenerative Medicine and Health Guangdong Laboratory, Guangzhou, China.
Chen L; MOE Key Laboratory of Tumor Molecular Biology and Key Laboratory of Functional Protein Research of Guangdong Higher Education Institutes, Institute of Life and Health Engineering, College of Life Science and Technology, Jinan University, Guangzhou 510632, China.
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Źródło :
Theranostics [Theranostics] 2021 May 03; Vol. 11 (13), pp. 6592-6606. Date of Electronic Publication: 2021 May 03 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Carcinoma, Non-Small-Cell Lung/*drug therapy
Lung Neoplasms/*drug therapy
Neoplasm Proteins/*antagonists & inhibitors
Nuclear Proteins/*deficiency
Receptor, Transforming Growth Factor-beta Type II/*antagonists & inhibitors
Trans-Activators/*deficiency
Adaptor Proteins, Signal Transducing/physiology ; Animals ; Antineoplastic Agents/pharmacology ; Antineoplastic Agents/therapeutic use ; Carcinoma, Non-Small-Cell Lung/genetics ; Down-Regulation ; Drug Synergism ; Gene Expression Regulation, Neoplastic ; Gene Silencing ; Histone Code ; Humans ; Lung Neoplasms/genetics ; Methylation ; Mice, Transgenic ; Neoplasm Proteins/biosynthesis ; Neoplasm Proteins/genetics ; Neoplasm Proteins/physiology ; Neoplastic Stem Cells/pathology ; Nuclear Proteins/biosynthesis ; Nuclear Proteins/genetics ; Nuclear Proteins/physiology ; Promoter Regions, Genetic ; Protein Kinase Inhibitors/pharmacology ; Protein Kinase Inhibitors/therapeutic use ; Protein Processing, Post-Translational ; Protein-Arginine N-Methyltransferases/physiology ; Receptor, Transforming Growth Factor-beta Type II/genetics ; Signal Transduction ; Trans-Activators/biosynthesis ; Trans-Activators/genetics ; Trans-Activators/physiology ; Tumor Burden
Czasopismo naukowe
Tytuł :
Sage controls silk gland development by regulating Dfd in Bombyx mori.
Autorzy :
Hou S; State Key Laboratory of Silkworm Genome Biology, Southwest University, Chongqing, 400716, China.
Tao C; State Key Laboratory of Silkworm Genome Biology, Southwest University, Chongqing, 400716, China.
Yang H; State Key Laboratory of Silkworm Genome Biology, Southwest University, Chongqing, 400716, China.
Cheng T; State Key Laboratory of Silkworm Genome Biology, Southwest University, Chongqing, 400716, China; Cancer Center, Medical Research Institute, Southwest University, Chongqing, China.
Liu C; State Key Laboratory of Silkworm Genome Biology, Southwest University, Chongqing, 400716, China; Chongqing Engineering and Technology Research Center for Silk Biomaterials and Regenerative Medicine, China. Electronic address: .
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Źródło :
Insect biochemistry and molecular biology [Insect Biochem Mol Biol] 2021 May; Vol. 132, pp. 103568. Date of Electronic Publication: 2021 Mar 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Bombyx*/genetics
Bombyx*/metabolism
Silk*/biosynthesis
Silk*/genetics
Silk*/metabolism
Trans-Activators*/genetics
Trans-Activators*/metabolism
Animals ; Fibroins/biosynthesis ; Fibroins/genetics ; Fibroins/metabolism ; Gene Expression Regulation ; Genes, Insect ; Insect Proteins/biosynthesis ; Insect Proteins/genetics ; Insect Proteins/metabolism ; Larva/genetics ; Larva/metabolism ; RNA Interference ; Salivary Glands/metabolism
Czasopismo naukowe
Tytuł :
POU2AF1 promotes MSCs adipogenesis by inhibiting HDAC1 expression.
Autorzy :
Wang Y; Department of Cardiology, Geriatric Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.
Wang L; Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.
Su Z; Department of Biotherapy, Second Affiliated Hospital, Nanjing Medical University, Nanjing, Jiangsu, China.
Sun W; Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.
Zhang M; Department of Gynecological Tumor, Nanjing Maternity and Child Health Hospital, Nanjing, Jiangsu, China.
Yang C; Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.
Zhou J; Department of Cardiovascular Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.
Jiang L; Department of Pediatrics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.
Kong X; Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.
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Źródło :
Adipocyte [Adipocyte] 2021 Dec; Vol. 10 (1), pp. 251-263.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Histone Deacetylase 1/*genetics
Mesenchymal Stem Cells/*metabolism
Trans-Activators/*metabolism
Adipogenesis/genetics ; Adipose Tissue/metabolism ; Histone Deacetylase 1/metabolism ; Humans ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Signal Transduction ; Trans-Activators/genetics
Czasopismo naukowe
Tytuł :
Mechanism Underlying the Role of LuxR Family Transcriptional Regulator abaR in Biofilm Formation by Acinetobacter baumannii.
Autorzy :
Sun X; Department of Burn, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Xiang J; Department of Burn, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China. .
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Źródło :
Current microbiology [Curr Microbiol] 2021 Nov; Vol. 78 (11), pp. 3936-3944. Date of Electronic Publication: 2021 Sep 14.
Typ publikacji :
Journal Article
MeSH Terms :
Acinetobacter baumannii*/genetics
Repressor Proteins/*physiology
Trans-Activators/*physiology
Biofilms ; Repressor Proteins/genetics ; Trans-Activators/genetics
Czasopismo naukowe
Tytuł :
Overexpression of Flii during Murine Embryonic Development Increases Symmetrical Division of Epidermal Progenitor Cells.
Autorzy :
Yang GN; Regenerative Medicine, Future Industries Institute, University of South Australia, Adelaide, SA 5000, Australia.; Cell Therapy Manufacturing Cooperative Research Centre, Adelaide, SA 5000, Australia.
Ahangar P; Regenerative Medicine, Future Industries Institute, University of South Australia, Adelaide, SA 5000, Australia.
Strudwick XL; Regenerative Medicine, Future Industries Institute, University of South Australia, Adelaide, SA 5000, Australia.
Kopecki Z; Regenerative Medicine, Future Industries Institute, University of South Australia, Adelaide, SA 5000, Australia.
Cowin AJ; Regenerative Medicine, Future Industries Institute, University of South Australia, Adelaide, SA 5000, Australia.; Cell Therapy Manufacturing Cooperative Research Centre, Adelaide, SA 5000, Australia.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jul 30; Vol. 22 (15). Date of Electronic Publication: 2021 Jul 30.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Division*
Microfilament Proteins/*genetics
Mouse Embryonic Stem Cells/*metabolism
Skin/*metabolism
Trans-Activators/*genetics
Animals ; Cells, Cultured ; Keratinocytes/cytology ; Keratinocytes/metabolism ; Mice ; Mice, Inbred BALB C ; Microfilament Proteins/metabolism ; Mouse Embryonic Stem Cells/cytology ; SOX9 Transcription Factor/metabolism ; Skin/embryology ; Trans-Activators/metabolism ; beta Catenin/metabolism
Czasopismo naukowe
Tytuł :
Acetylation of the CspA family protein CspC controls the type III secretion system through translational regulation of exsA in Pseudomonas aeruginosa.
Autorzy :
Li S; State Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Molecular Microbiology and Technology of the Ministry of Education, Department of Microbiology, College of Life Sciences, Nankai University, Tianjin 300071, China.
Weng Y; State Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Molecular Microbiology and Technology of the Ministry of Education, Department of Microbiology, College of Life Sciences, Nankai University, Tianjin 300071, China.
Li X; State Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Molecular Microbiology and Technology of the Ministry of Education, Department of Microbiology, College of Life Sciences, Nankai University, Tianjin 300071, China.
Yue Z; State Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Molecular Microbiology and Technology of the Ministry of Education, Department of Microbiology, College of Life Sciences, Nankai University, Tianjin 300071, China.
Chai Z; State Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Molecular Microbiology and Technology of the Ministry of Education, Department of Microbiology, College of Life Sciences, Nankai University, Tianjin 300071, China.
Zhang X; State Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Molecular Microbiology and Technology of the Ministry of Education, Department of Microbiology, College of Life Sciences, Nankai University, Tianjin 300071, China.
Gong X; State Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Molecular Microbiology and Technology of the Ministry of Education, Department of Microbiology, College of Life Sciences, Nankai University, Tianjin 300071, China.
Pan X; State Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Molecular Microbiology and Technology of the Ministry of Education, Department of Microbiology, College of Life Sciences, Nankai University, Tianjin 300071, China.
Jin Y; State Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Molecular Microbiology and Technology of the Ministry of Education, Department of Microbiology, College of Life Sciences, Nankai University, Tianjin 300071, China.
Bai F; State Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Molecular Microbiology and Technology of the Ministry of Education, Department of Microbiology, College of Life Sciences, Nankai University, Tianjin 300071, China.
Cheng Z; State Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Molecular Microbiology and Technology of the Ministry of Education, Department of Microbiology, College of Life Sciences, Nankai University, Tianjin 300071, China.
Wu W; State Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Molecular Microbiology and Technology of the Ministry of Education, Department of Microbiology, College of Life Sciences, Nankai University, Tianjin 300071, China.
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Źródło :
Nucleic acids research [Nucleic Acids Res] 2021 Jul 09; Vol. 49 (12), pp. 6756-6770.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation, Bacterial*
Bacterial Proteins/*genetics
Bacterial Proteins/*metabolism
Heat-Shock Proteins/*metabolism
Pseudomonas aeruginosa/*genetics
Trans-Activators/*genetics
Type III Secretion Systems/*genetics
A549 Cells ; Acetylation ; Animals ; Bacterial Proteins/biosynthesis ; Humans ; Mice ; Pneumonia, Bacterial/microbiology ; Promoter Regions, Genetic ; Protein Biosynthesis ; Pseudomonas aeruginosa/metabolism ; Pseudomonas aeruginosa/pathogenicity ; Trans-Activators/biosynthesis ; Virulence
Czasopismo naukowe

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