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Title:
Mechanisms and Functions of the RNA Polymerase II General Transcription Machinery during the Transcription Cycle.
Authors:
Archuleta SR; Department of Biochemistry, University of Colorado Boulder, 596 UCB, Boulder, CO 80309, USA.
Goodrich JA; Department of Biochemistry, University of Colorado Boulder, 596 UCB, Boulder, CO 80309, USA.
Kugel JF; Department of Biochemistry, University of Colorado Boulder, 596 UCB, Boulder, CO 80309, USA.
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Source:
Biomolecules [Biomolecules] 2024 Feb 01; Vol. 14 (2). Date of Electronic Publication: 2024 Feb 01.
Publication Type:
Journal Article; Review
MeSH Terms:
RNA Polymerase II*/chemistry
Transcription, Genetic*
Humans ; Transcription Factors/metabolism ; Promoter Regions, Genetic ; RNA, Messenger
Academic Journal
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Title:
Transcription readthrough is prevalent in healthy human tissues and associated with inherent genomic features.
Authors:
Caldas P; Associate Laboratory i4HB - Institute for Health and Bioeconomy, NOVA School of Science and Technology, Universidade NOVA de Lisboa, 2829-516, Caparica, Portugal. .; UCIBIO - Applied Molecular Biosciences Unit, Department of Life Sciences, NOVA School of Science and Technology, Universidade NOVA de Lisboa, 2829-516, Caparica, Portugal. .
Luz M; Associate Laboratory i4HB - Institute for Health and Bioeconomy, NOVA School of Science and Technology, Universidade NOVA de Lisboa, 2829-516, Caparica, Portugal.; UCIBIO - Applied Molecular Biosciences Unit, Department of Life Sciences, NOVA School of Science and Technology, Universidade NOVA de Lisboa, 2829-516, Caparica, Portugal.
Baseggio S; Associate Laboratory i4HB - Institute for Health and Bioeconomy, NOVA School of Science and Technology, Universidade NOVA de Lisboa, 2829-516, Caparica, Portugal.; UCIBIO - Applied Molecular Biosciences Unit, Department of Life Sciences, NOVA School of Science and Technology, Universidade NOVA de Lisboa, 2829-516, Caparica, Portugal.
Andrade R; Associate Laboratory i4HB - Institute for Health and Bioeconomy, NOVA School of Science and Technology, Universidade NOVA de Lisboa, 2829-516, Caparica, Portugal.; UCIBIO - Applied Molecular Biosciences Unit, Department of Life Sciences, NOVA School of Science and Technology, Universidade NOVA de Lisboa, 2829-516, Caparica, Portugal.
Sobral D; Associate Laboratory i4HB - Institute for Health and Bioeconomy, NOVA School of Science and Technology, Universidade NOVA de Lisboa, 2829-516, Caparica, Portugal.; UCIBIO - Applied Molecular Biosciences Unit, Department of Life Sciences, NOVA School of Science and Technology, Universidade NOVA de Lisboa, 2829-516, Caparica, Portugal.; Genomics and Bioinformatics Unit, Department of Infectious Diseases, National Institute of Health Doutor Ricardo Jorge (INSA), Lisbon, Portugal.
Grosso AR; Associate Laboratory i4HB - Institute for Health and Bioeconomy, NOVA School of Science and Technology, Universidade NOVA de Lisboa, 2829-516, Caparica, Portugal. .; UCIBIO - Applied Molecular Biosciences Unit, Department of Life Sciences, NOVA School of Science and Technology, Universidade NOVA de Lisboa, 2829-516, Caparica, Portugal. .
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Source:
Communications biology [Commun Biol] 2024 Jan 15; Vol. 7 (1), pp. 100. Date of Electronic Publication: 2024 Jan 15.
Publication Type:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Transcription, Genetic*
MicroRNAs*
Humans ; Genome ; Genomics ; Transcriptome
Academic Journal
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Title:
eRNA co-expression network uncovers TF dependency and convergent cooperativity.
Authors:
Lee SA; Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY, 14850, USA.
Kristjánsdóttir K; Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY, 14850, USA.
Kwak H; Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY, 14850, USA. .
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Source:
Scientific reports [Sci Rep] 2023 Nov 04; Vol. 13 (1), pp. 19085. Date of Electronic Publication: 2023 Nov 04.
Publication Type:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
Transcription, Genetic*
Enhancer Elements, Genetic*
Humans ; RNA/genetics ; Regulatory Elements, Transcriptional ; Promoter Regions, Genetic
Academic Journal
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Title:
To Break or Not to Break: The Role of TOP2B in Transcription.
Authors:
Cowell IG; Biosciences Institute, The Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne NE2 4HH, UK.
Casement JW; Bioinformatics Support Unit, The Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne NE2 4HH, UK.
Austin CA; Biosciences Institute, The Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne NE2 4HH, UK.
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Source:
International journal of molecular sciences [Int J Mol Sci] 2023 Sep 30; Vol. 24 (19). Date of Electronic Publication: 2023 Sep 30.
Publication Type:
Journal Article; Review
MeSH Terms:
DNA Topoisomerases, Type II*/genetics
DNA Topoisomerases, Type II*/metabolism
Transcription, Genetic*
Animals ; DNA ; DNA Replication ; DNA-Binding Proteins/metabolism ; Gene Expression Regulation ; Mammals/metabolism ; Humans
Academic Journal
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Title:
The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation.
Authors:
Gu X; Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA.
Nardone C; Division of Genetics, Department of Medicine, Howard Hughes Medical Institute, Brigham and Women's Hospital, Boston, MA 02115, USA.; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.
Kamitaki N; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.; Department of Biomedical Informatics, Harvard Medical School, Boston, MA 02115, USA.
Mao A; Division of Genetics, Department of Medicine, Howard Hughes Medical Institute, Brigham and Women's Hospital, Boston, MA 02115, USA.; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.; Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA.
Elledge SJ; Division of Genetics, Department of Medicine, Howard Hughes Medical Institute, Brigham and Women's Hospital, Boston, MA 02115, USA.; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.
Greenberg ME; Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA.
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Source:
Science (New York, N.Y.) [Science] 2023 Aug 25; Vol. 381 (6660), pp. eadh5021. Date of Electronic Publication: 2023 Aug 25.
Publication Type:
Journal Article
MeSH Terms:
Nuclear Proteins*/chemistry
Nuclear Proteins*/genetics
Nuclear Proteins*/metabolism
Proteasome Endopeptidase Complex*
Proteolysis*
Genes, Immediate-Early*
Transcription, Genetic*
Ubiquitin ; Ubiquitination ; HEK293 Cells ; NIH 3T3 Cells
Academic Journal
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Title:
Metabolic control of transcription.
Authors:
Taylor EB; Department of Molecular Physiology and Biophysics and Fraternal Orders of Eagle Diabetes Research Center, Holden Comprehensive Cancer Center, Abboud Cardiovascular Research Center, Pappajohn Biomedical Discovery Institute, Carver College of Medicine, University of Iowa, Iowa City, IA, USA.
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Source:
Science (New York, N.Y.) [Science] 2023 Jul 14; Vol. 381 (6654), pp. 125-126. Date of Electronic Publication: 2023 Jul 13.
Publication Type:
Journal Article
MeSH Terms:
Ketoglutarate Dehydrogenase Complex*/genetics
Protein Processing, Post-Translational*
Transcription, Genetic*
Gene Expression Regulation, Plant*
Arabidopsis*/enzymology
Arabidopsis*/genetics
Methylation
Academic Journal
Full Text  Link opens in a new window Full TextDetails
Title:
Chromatin expansion microscopy reveals nanoscale organization of transcription and chromatin.
Authors:
Pownall ME; Department of Genetics, Yale University School of Medicine, New Haven, CT 06510, USA.
Miao L; Department of Genetics, Yale University School of Medicine, New Haven, CT 06510, USA.
Vejnar CE; Department of Genetics, Yale University School of Medicine, New Haven, CT 06510, USA.
M'Saad O; Department of Cell Biology, Yale University School of Medicine, New Haven, CT 06510, USA.; Department of Biomedical Engineering, Yale University, New Haven, CT 06510, USA.
Sherrard A; Department of Genetics, Yale University School of Medicine, New Haven, CT 06510, USA.
Frederick MA; Institute for Regenerative Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Benitez MDJ; Department of Genetics, Yale University School of Medicine, New Haven, CT 06510, USA.
Boswell CW; Department of Genetics, Yale University School of Medicine, New Haven, CT 06510, USA.
Zaret KS; Institute for Regenerative Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Bewersdorf J; Department of Cell Biology, Yale University School of Medicine, New Haven, CT 06510, USA.; Department of Biomedical Engineering, Yale University, New Haven, CT 06510, USA.; Kavli Institute for Neuroscience, Yale University School of Medicine, New Haven, CT 06510, USA.; Department of Physics, Yale University, New Haven, CT 06510, USA.; Nanobiology Institute, Yale University, West Haven, CT 06477, USA.
Giraldez AJ; Department of Genetics, Yale University School of Medicine, New Haven, CT 06510, USA.; Yale Stem Cell Center, Yale University School of Medicine, New Haven, CT 06510, USA.; Yale Cancer Center, Yale University School of Medicine, New Haven, CT 06510, USA.
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Source:
Science (New York, N.Y.) [Science] 2023 Jul 07; Vol. 381 (6653), pp. 92-100. Date of Electronic Publication: 2023 Jul 06.
Publication Type:
Journal Article
MeSH Terms:
Chromatin*/chemistry
Transcription, Genetic*
Microscopy, Fluorescence*/methods
Zygote*/metabolism
Nucleosomes/chemistry ; RNA Polymerase II/chemistry ; RNA Polymerase II/metabolism ; Animals ; Zebrafish ; Embryo, Nonmammalian ; Nanog Homeobox Protein/chemistry ; Nanog Homeobox Protein/metabolism
Academic Journal
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Title:
An expanded view of transcription.
Authors:
Stasevich TJ; Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO, USA.
Kimura H; Cell Biology Center, Institute of Innovative Research, Tokyo Institute of Technology, Yokohama, Japan.
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Source:
Science (New York, N.Y.) [Science] 2023 Jul 07; Vol. 381 (6653), pp. 26-27. Date of Electronic Publication: 2023 Jul 06.
Publication Type:
Journal Article
MeSH Terms:
Chromatin*
Transcription, Genetic*
Microscopy, Fluorescence*/methods
Animals ; Molecular Imaging/methods
Academic Journal
Full Text  Link opens in a new window Full TextDetails
Title:
Stochastic motion and transcriptional dynamics of pairs of distal DNA loci on a compacted chromosome.
Authors:
Brückner DB; Institute of Science and Technology, Am Campus 1, Klosterneuburg, Austria.
Chen H; School of Life Science and Technology, ShanghaiTech University, Shanghai, China.; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ, USA.
Barinov L; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ, USA.; Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Zoller B; Joseph Henry Laboratories of Physics, Princeton University, Princeton, NJ, USA.; Department of Developmental and Stem Cell Biology, CNRS UMR3738 Paris Cité, Institut Pasteur, Paris, France.
Gregor T; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ, USA.; Joseph Henry Laboratories of Physics, Princeton University, Princeton, NJ, USA.; Department of Developmental and Stem Cell Biology, CNRS UMR3738 Paris Cité, Institut Pasteur, Paris, France.
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Source:
Science (New York, N.Y.) [Science] 2023 Jun 30; Vol. 380 (6652), pp. 1357-1362. Date of Electronic Publication: 2023 Jun 29.
Publication Type:
Journal Article
MeSH Terms:
Chromosomes*/chemistry
Chromosomes*/genetics
DNA*/chemistry
DNA*/genetics
Transcription, Genetic*
Molecular Imaging*/methods
Enhancer Elements, Genetic*
Promoter Regions, Genetic*
Cell Nucleus/metabolism ; Eukaryota ; Polymers/chemistry ; Animals ; Drosophila
Academic Journal
Full Text  Link opens in a new window Full TextDetails
Title:
Identification and characterization of transcribed enhancers during cerebellar development through enhancer RNA analysis.
Authors:
Ramirez M; Centre for Molecular Medicine and Therapeutics, BC Children's Hospital Research Institute, 950 W 28th Ave, V6H 3V5, Vancouver, BC, Canada.; University of British Columbia, V6T 1Z4, Vancouver, BC, Canada.
Robert R; Centre for Molecular Medicine and Therapeutics, BC Children's Hospital Research Institute, 950 W 28th Ave, V6H 3V5, Vancouver, BC, Canada.; University of British Columbia, V6T 1Z4, Vancouver, BC, Canada.
Yeung J; Centre for Molecular Medicine and Therapeutics, BC Children's Hospital Research Institute, 950 W 28th Ave, V6H 3V5, Vancouver, BC, Canada.; University of British Columbia, V6T 1Z4, Vancouver, BC, Canada.
Wu J; Centre for Molecular Medicine and Therapeutics, BC Children's Hospital Research Institute, 950 W 28th Ave, V6H 3V5, Vancouver, BC, Canada.; University of British Columbia, V6T 1Z4, Vancouver, BC, Canada.
Abdalla-Wyse A; Centre for Molecular Medicine and Therapeutics, BC Children's Hospital Research Institute, 950 W 28th Ave, V6H 3V5, Vancouver, BC, Canada.; University of British Columbia, V6T 1Z4, Vancouver, BC, Canada.
Goldowitz D; Centre for Molecular Medicine and Therapeutics, BC Children's Hospital Research Institute, 950 W 28th Ave, V6H 3V5, Vancouver, BC, Canada. .; University of British Columbia, V6T 1Z4, Vancouver, BC, Canada. .
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Corporate Authors:
FANTOM 5 Consortium
Source:
BMC genomics [BMC Genomics] 2023 Jun 26; Vol. 24 (1), pp. 351. Date of Electronic Publication: 2023 Jun 26.
Publication Type:
Journal Article
MeSH Terms:
Brain*/embryology
Brain*/metabolism
Transcription, Genetic*
Gene Expression Regulation, Developmental*
Sequence Analysis, RNA ; Animals ; Mice ; Enhancer Elements, Genetic ; RNA/genetics
Academic Journal
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Title:
SUMO-dependent transcriptional repression by Sox2 inhibits the proliferation of neural stem cells.
Authors:
Marelli E; School of Life Sciences, University of Nottingham, Nottingham, Nottinghamshire, United Kingdom.
Hughes J; School of Life Sciences, University of Nottingham, Nottingham, Nottinghamshire, United Kingdom.
Scotting PJ; School of Life Sciences, University of Nottingham, Nottingham, Nottinghamshire, United Kingdom.
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Source:
PloS one [PLoS One] 2024 Mar 20; Vol. 19 (3), pp. e0298818. Date of Electronic Publication: 2024 Mar 20 (Print Publication: 2024).
Publication Type:
Journal Article
MeSH Terms:
Neural Stem Cells*/metabolism
Transcription, Genetic ; Embryonic Stem Cells ; Gene Expression Regulation, Developmental ; Cell Proliferation ; SOXB1 Transcription Factors/genetics ; SOXB1 Transcription Factors/metabolism ; Cell Differentiation/genetics
Academic Journal
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Title:
Oxidative Stress-Mediated Repression of Virulence Gene Transcription and Biofilm Formation as Antibacterial Action of Cinnamomum burmannii Essential Oil on Staphylococcus aureus .
Authors:
Shi L; College of Biological Sciences and Biotechnology, National Engineering Laboratory for Tree Breeding, Key Laboratory of Genetics and Breeding in Forest Trees and Ornamental Plants, Ministry of Education, Tree and Ornamental Plant Breeding and Biotechnology Laboratory of National Forestry and Grassland Administration, Beijing Forestry University, Beijing 100083, China.
Lin W; College of Biological Sciences and Biotechnology, National Engineering Laboratory for Tree Breeding, Key Laboratory of Genetics and Breeding in Forest Trees and Ornamental Plants, Ministry of Education, Tree and Ornamental Plant Breeding and Biotechnology Laboratory of National Forestry and Grassland Administration, Beijing Forestry University, Beijing 100083, China.
Cai Y; Guangdong Provincial Key Laboratory of Silviculture, Protection and Utilization, Guangdong Academy of Forestry, Guangzhou 510520, China.
Chen F; College of Biological Sciences and Biotechnology, National Engineering Laboratory for Tree Breeding, Key Laboratory of Genetics and Breeding in Forest Trees and Ornamental Plants, Ministry of Education, Tree and Ornamental Plant Breeding and Biotechnology Laboratory of National Forestry and Grassland Administration, Beijing Forestry University, Beijing 100083, China.
Zhang Q; Guangdong Provincial Key Laboratory of Silviculture, Protection and Utilization, Guangdong Academy of Forestry, Guangzhou 510520, China.
Liang D; Guangdong Provincial Key Laboratory of Silviculture, Protection and Utilization, Guangdong Academy of Forestry, Guangzhou 510520, China.
Xiu Y; College of Biological Sciences and Biotechnology, National Engineering Laboratory for Tree Breeding, Key Laboratory of Genetics and Breeding in Forest Trees and Ornamental Plants, Ministry of Education, Tree and Ornamental Plant Breeding and Biotechnology Laboratory of National Forestry and Grassland Administration, Beijing Forestry University, Beijing 100083, China.
Lin S; College of Biological Sciences and Biotechnology, National Engineering Laboratory for Tree Breeding, Key Laboratory of Genetics and Breeding in Forest Trees and Ornamental Plants, Ministry of Education, Tree and Ornamental Plant Breeding and Biotechnology Laboratory of National Forestry and Grassland Administration, Beijing Forestry University, Beijing 100083, China.
He B; Guangdong Provincial Key Laboratory of Silviculture, Protection and Utilization, Guangdong Academy of Forestry, Guangzhou 510520, China.
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Source:
International journal of molecular sciences [Int J Mol Sci] 2024 Mar 06; Vol. 25 (5). Date of Electronic Publication: 2024 Mar 06.
Publication Type:
Journal Article
MeSH Terms:
Oils, Volatile*/pharmacology
Cinnamomum*/genetics
Staphylococcus aureus/physiology ; Virulence ; Reactive Oxygen Species ; Anti-Bacterial Agents/pharmacology ; Biofilms ; Oxidative Stress ; Transcription, Genetic ; Peptide Hydrolases/genetics ; Microbial Sensitivity Tests
Academic Journal
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Title:
Differences in transcription initiation directionality underlie distinctions between plants and animals in chromatin modification patterns at genes and cis-regulatory elements.
Authors:
Silver BD; Department of Biology, Emory University, Atlanta, GA 30322, USA.; Graduate Program in Genetics and Molecular Biology, Emory University, Atlanta, GA 30322, USA.
Willett CG; Department of Biology, Emory University, Atlanta, GA 30322, USA.; Graduate Program in Genetics and Molecular Biology, Emory University, Atlanta, GA 30322, USA.
Maher KA; Department of Biology, Emory University, Atlanta, GA 30322, USA.; Graduate Program in Biochemistry, Cell, and Developmental Biology, Emory University, Atlanta, GA 30322, USA.; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
Wang D; Department of Biology, Emory University, Atlanta, GA 30322, USA.; School of Medicine, Emory University, Atlanta, GA 30322, USA.
Deal RB; Department of Biology, Emory University, Atlanta, GA 30322, USA.
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Source:
G3 (Bethesda, Md.) [G3 (Bethesda)] 2024 Mar 06; Vol. 14 (3).
Publication Type:
Journal Article
MeSH Terms:
Chromatin*/genetics
Arabidopsis*/genetics
Arabidopsis*/metabolism
Animals ; RNA Polymerase II/genetics ; RNA Polymerase II/metabolism ; Transcription, Genetic ; Drosophila melanogaster/genetics ; Drosophila melanogaster/metabolism ; Transcription Initiation Site ; Plants/genetics
Academic Journal
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Title:
PTEN Mediates the Silencing of Unintegrated HIV-1 DNA.
Authors:
Phan AT; Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY 14642, USA.
Zhu Y; Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY 14642, USA.
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Source:
Viruses [Viruses] 2024 Feb 14; Vol. 16 (2). Date of Electronic Publication: 2024 Feb 14.
Publication Type:
Journal Article
MeSH Terms:
HIV-1*/physiology
NF-kappa B*/metabolism
DNA, Viral/genetics ; DNA, Viral/metabolism ; Phosphatidylinositol 3-Kinases/genetics ; Phosphatidylinositol 3-Kinases/metabolism ; Phosphoric Monoester Hydrolases/metabolism ; Proto-Oncogene Proteins c-akt/genetics ; Proto-Oncogene Proteins c-akt/metabolism ; Transcription Factor AP-1/metabolism ; Transcription, Genetic ; Humans
Academic Journal
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Title:
HIV-1 Transcription and Latency in the Spotlight.
Authors:
D'Orso I; Department of Microbiology, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
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Source:
Viruses [Viruses] 2024 Feb 04; Vol. 16 (2). Date of Electronic Publication: 2024 Feb 04.
Publication Type:
Editorial
MeSH Terms:
HIV-1*/genetics
HIV Infections*
HIV Seropositivity*
Humans ; Virus Latency/genetics ; Proviruses/genetics ; Transcription, Genetic
Editorial & Opinion
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Title:
Transcriptional Regulation Technology for Gene Perturbation in Fission Yeast.
Authors:
Ishikawa K; Department of Cell Biology, Institute of Life Science, Kurume University, Asahi-machi 67, Fukuoka 830-0011, Japan.
Saitoh S; Department of Cell Biology, Institute of Life Science, Kurume University, Asahi-machi 67, Fukuoka 830-0011, Japan.
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Source:
Biomolecules [Biomolecules] 2023 Apr 21; Vol. 13 (4). Date of Electronic Publication: 2023 Apr 21.
Publication Type:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Transcription, Genetic*
Schizosaccharomyces*/genetics
Gene Editing*/methods
CRISPR-Cas Systems*
Gene Knockdown Techniques*
Gene Expression Regulation, Fungal ; Mutation ; Genome-Wide Association Study
Academic Journal
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Title:
Neurog1-Derived Peptides RMNE1 and DualPep-Shine Penetrate the Skin and Inhibit Melanin Synthesis by Regulating MITF Transcription.
Authors:
Song EC; Remedi Co., Ltd., Research Center, Incheon 21990, Republic of Korea.
Park C; Remedi Co., Ltd., Research Center, Incheon 21990, Republic of Korea.
Shin Y; Remedi Co., Ltd., Research Center, Incheon 21990, Republic of Korea.
Kim WK; Remedi Co., Ltd., Research Center, Incheon 21990, Republic of Korea.
Kim SB; College of Pharmacy, Sahmyook University, Seoul 01795, Republic of Korea.
Cho S; Remedi Co., Ltd., Research Center, Incheon 21990, Republic of Korea.
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Source:
International journal of molecular sciences [Int J Mol Sci] 2023 Mar 24; Vol. 24 (7). Date of Electronic Publication: 2023 Mar 24.
Publication Type:
Journal Article
MeSH Terms:
Melanins*/antagonists & inhibitors
Skin Pigmentation*/drug effects
Microphthalmia-Associated Transcription Factor*/genetics
Transcription, Genetic*/drug effects
Cell-Penetrating Peptides*/chemistry
Cell-Penetrating Peptides*/pharmacology
Skin Lightening Preparations*/chemistry
Skin Lightening Preparations*/pharmacology
Nerve Tissue Proteins*/chemistry
Nerve Tissue Proteins*/pharmacology
Basic Helix-Loop-Helix Transcription Factors*/chemistry
Basic Helix-Loop-Helix Transcription Factors*/pharmacology
Melanocytes*/drug effects
Melanocytes*/metabolism
alpha-MSH/antagonists & inhibitors ; alpha-MSH/metabolism ; Humans ; Melanoma, Experimental ; Keratinocytes/drug effects ; Keratinocytes/metabolism ; Epidermis/drug effects ; Epidermis/metabolism
Academic Journal
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Title:
Characterization of RNA polymerase II trigger loop mutations using molecular dynamics simulations and machine learning.
Authors:
Dutagaci B; Department of Molecular and Cell Biology, University of California Merced, Merced, California, United States of America.
Duan B; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
Qiu C; Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America.
Kaplan CD; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
Feig M; Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, Michigan, United States of America.
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Source:
PLoS computational biology [PLoS Comput Biol] 2023 Mar 22; Vol. 19 (3), pp. e1010999. Date of Electronic Publication: 2023 Mar 22 (Print Publication: 2023).
Publication Type:
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural
MeSH Terms:
RNA Polymerase II*/metabolism
Transcription, Genetic*
Molecular Dynamics Simulation ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae/metabolism ; Mutation ; DNA-Directed RNA Polymerases/metabolism
Academic Journal
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Title:
Structural and Molecular Basis for Mitochondrial DNA Replication and Transcription in Health and Antiviral Drug Toxicity.
Authors:
Park J; Department of Biochemistry and Molecular Biology, Sealy Center for Structural Biology and Molecular Biophysics, University of Texas Medical Branch, Galveston, TX 77555, USA.; Department of Pharmacology and Toxicology, Sealy Center for Structural Biology and Molecular Biophysics, University of Texas Medical Branch, Galveston, TX 77555, USA.
Baruch-Torres N; Department of Biochemistry and Molecular Biology, Sealy Center for Structural Biology and Molecular Biophysics, University of Texas Medical Branch, Galveston, TX 77555, USA.; Department of Pharmacology and Toxicology, Sealy Center for Structural Biology and Molecular Biophysics, University of Texas Medical Branch, Galveston, TX 77555, USA.
Yin YW; Department of Biochemistry and Molecular Biology, Sealy Center for Structural Biology and Molecular Biophysics, University of Texas Medical Branch, Galveston, TX 77555, USA.; Department of Pharmacology and Toxicology, Sealy Center for Structural Biology and Molecular Biophysics, University of Texas Medical Branch, Galveston, TX 77555, USA.
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Source:
Molecules (Basel, Switzerland) [Molecules] 2023 Feb 14; Vol. 28 (4). Date of Electronic Publication: 2023 Feb 14.
Publication Type:
Journal Article; Review
MeSH Terms:
DNA Replication*
Transcription, Genetic*
Humans ; RNA, Mitochondrial ; Transcription Factors/metabolism ; DNA, Mitochondrial/genetics ; Mitochondrial Proteins/metabolism ; DNA-Directed RNA Polymerases/genetics ; Antiviral Agents
Academic Journal
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Title:
Slight Variations in the Sequence Downstream of the Polyadenylation Signal Significantly Increase Transgene Expression in HEK293T and CHO Cells.
Authors:
Omelina ES; Department of Regulation of Genetic Processes, Institute of Molecular and Cellular Biology, SB RAS, 630090 Novosibirsk, Russia.; Laboratory of Biotechnology, Novosibirsk State Agrarian University, 630039 Novosibirsk, Russia.
Letiagina AE; Department of Regulation of Genetic Processes, Institute of Molecular and Cellular Biology, SB RAS, 630090 Novosibirsk, Russia.
Boldyreva LV; Department of Regulation of Genetic Processes, Institute of Molecular and Cellular Biology, SB RAS, 630090 Novosibirsk, Russia.; Laboratory of Experimental Models of Cognitive and Emotional Disorders, Scientific-Research Institute of Neurosciences and Medicine, 630117 Novosibirsk, Russia.
Ogienko AA; Department of Regulation of Genetic Processes, Institute of Molecular and Cellular Biology, SB RAS, 630090 Novosibirsk, Russia.
Galimova YA; Department of Regulation of Genetic Processes, Institute of Molecular and Cellular Biology, SB RAS, 630090 Novosibirsk, Russia.
Yarinich LA; Department of Regulation of Genetic Processes, Institute of Molecular and Cellular Biology, SB RAS, 630090 Novosibirsk, Russia.
Pindyurin AV; Department of Regulation of Genetic Processes, Institute of Molecular and Cellular Biology, SB RAS, 630090 Novosibirsk, Russia.
Andreyeva EN; Department of Regulation of Genetic Processes, Institute of Molecular and Cellular Biology, SB RAS, 630090 Novosibirsk, Russia.
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Source:
International journal of molecular sciences [Int J Mol Sci] 2022 Dec 07; Vol. 23 (24). Date of Electronic Publication: 2022 Dec 07.
Publication Type:
Journal Article
MeSH Terms:
Polyadenylation*/genetics
Transcription, Genetic*
Cricetinae ; Animals ; Humans ; HEK293 Cells ; Cricetulus ; CHO Cells ; RNA, Messenger/genetics ; Transgenes
Academic Journal
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Showing 1-20 from 24323 results

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