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Wyszukujesz frazę ""Transcription, Genetic"" wg kryterium: Temat


Tytuł :
Embryonic tissue differentiation is characterized by transitions in cell cycle dynamic-associated core promoter regulation.
Autorzy :
Wragg JW; Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, B15 2TT, UK.
Roos L; Institute of Clinical Sciences and MRC Clinical Sciences Centre, Faculty of Medicine, Imperial College London, London, W12 0NN, UK.
Vucenovic D; Institute of Clinical Sciences and MRC Clinical Sciences Centre, Faculty of Medicine, Imperial College London, London, W12 0NN, UK.
Cvetesic N; Institute of Clinical Sciences and MRC Clinical Sciences Centre, Faculty of Medicine, Imperial College London, London, W12 0NN, UK.
Lenhard B; Institute of Clinical Sciences and MRC Clinical Sciences Centre, Faculty of Medicine, Imperial College London, London, W12 0NN, UK.
Müller F; Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, B15 2TT, UK.
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Źródło :
Nucleic acids research [Nucleic Acids Res] 2020 Sep 04; Vol. 48 (15), pp. 8374-8392.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Transcription Initiation Site*
Transcription, Genetic*
Gene Regulatory Networks/*genetics
Promoter Regions, Genetic/*genetics
Animals ; Binding Sites/genetics ; Cell Cycle/genetics ; Cell Differentiation/genetics ; Cell Proliferation/genetics ; Embryonic Development/genetics ; Humans ; Morphogenesis/genetics ; Sp1 Transcription Factor/genetics ; TATA Box/genetics ; Zebrafish/genetics
Czasopismo naukowe
Tytuł :
Identification of the human DPR core promoter element using machine learning.
Autorzy :
Vo Ngoc L; Section of Molecular Biology, University of California, San Diego, La Jolla, CA, USA.
Huang CY; Section of Molecular Biology, University of California, San Diego, La Jolla, CA, USA.
Cassidy CJ; Section of Molecular Biology, University of California, San Diego, La Jolla, CA, USA.
Medrano C; Section of Molecular Biology, University of California, San Diego, La Jolla, CA, USA.
Kadonaga JT; Section of Molecular Biology, University of California, San Diego, La Jolla, CA, USA. .
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Źródło :
Nature [Nature] 2020 Sep; Vol. 585 (7825), pp. 459-463. Date of Electronic Publication: 2020 Sep 09.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Support Vector Machine*
Transcription, Genetic*
Consensus Sequence/*genetics
Gene Expression Regulation/*genetics
Promoter Regions, Genetic/*genetics
RNA Polymerase II/*metabolism
Base Sequence ; Cells/metabolism ; Computer Simulation ; Datasets as Topic ; HeLa Cells ; High-Throughput Nucleotide Sequencing ; Humans ; Models, Genetic ; Mutagenesis ; TATA Box/genetics
Czasopismo naukowe
Tytuł :
Sp3 Transcription Factor Cooperates with the Kaposi's Sarcoma-Associated Herpesvirus ORF50 Protein To Synergistically Activate Specific Viral and Cellular Gene Promoters.
Autorzy :
Chen LY; Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang-Gung University, Taoyuan, Taiwan.
Chen LW; Department of Respiratory Care, Chang-Gung University of Science and Technology, Chiayi, Taiwan.; Department of Pediatric Surgery, Chang-Gung Memorial Hospital, Chiayi, Taiwan.
Peng KT; Department of Orthopedic Surgery, Chang-Gung Memorial Hospital, Chiayi, Taiwan.
Hung CH; Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang-Gung University, Taoyuan, Taiwan.
Chang PJ; Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang-Gung University, Taoyuan, Taiwan .; Department of Nephrology, Chang-Gung Memorial Hospital, Chiayi, Taiwan.
Wang SS; Department of Pediatric Surgery, Chang-Gung Memorial Hospital, Chiayi, Taiwan .; School of Medicine, Chang-Gung University, Taoyuan, Taiwan.
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Źródło :
Journal of virology [J Virol] 2020 Aug 31; Vol. 94 (18). Date of Electronic Publication: 2020 Aug 31 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Promoter Regions, Genetic*
Transcription, Genetic*
Herpesvirus 8, Human/*genetics
Immediate-Early Proteins/*genetics
Sp1 Transcription Factor/*genetics
Sp3 Transcription Factor/*genetics
Trans-Activators/*genetics
Animals ; Binding Sites ; Cell Line ; Cell Line, Tumor ; Clone Cells ; Fibroblasts/virology ; Gene Expression Regulation ; HEK293 Cells ; Herpesvirus 8, Human/metabolism ; Host-Pathogen Interactions/genetics ; Humans ; Immediate-Early Proteins/metabolism ; Immunoglobulin J Recombination Signal Sequence-Binding Protein/genetics ; Immunoglobulin J Recombination Signal Sequence-Binding Protein/metabolism ; Interleukin-10/genetics ; Interleukin-10/metabolism ; Lymphocytes/virology ; Mice ; Protein Binding ; Response Elements ; Signal Transduction ; Sp1 Transcription Factor/metabolism ; Sp3 Transcription Factor/metabolism ; Trans-Activators/metabolism ; Viral Proteins/genetics ; Viral Proteins/metabolism ; Viral Regulatory and Accessory Proteins/genetics ; Viral Regulatory and Accessory Proteins/metabolism
Czasopismo naukowe
Tytuł :
The critical region for viral RNA encapsidation in leader promoter of Nipah virus.
Autorzy :
Pong LY; Department of Biological Sciences and Biotechnology, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, 43600, UKM Bangi, Selangor Darul Ehsan, Malaysia.; Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Jalan Lagoon Selatan, 47500, Bandar Sunway, Selangor Darul Ehsan, Malaysia.
Rabu A; Department of Biological Sciences and Biotechnology, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, 43600, UKM Bangi, Selangor Darul Ehsan, Malaysia.
Ibrahim N; Department of Biological Sciences and Biotechnology, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, 43600, UKM Bangi, Selangor Darul Ehsan, Malaysia. .
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Źródło :
Molecular genetics and genomics : MGG [Mol Genet Genomics] 2020 Nov; Vol. 295 (6), pp. 1501-1516. Date of Electronic Publication: 2020 Aug 07.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation, Viral*
Promoter Regions, Genetic*
RNA, Viral*/physiology
Virus Assembly*
Nipah Virus/*genetics
5' Untranslated Regions ; Cell Line ; Mutagenesis ; Nucleocapsid Proteins/genetics ; RNA, Messenger ; Recombinant Proteins/genetics ; Transcription, Genetic
Czasopismo naukowe
Tytuł :
Pervasive and CpG-dependent promoter-like characteristics of transcribed enhancers.
Autorzy :
Steinhaus R; Berlin Institute of Health, Charitéplatz 1, 10117 Berlin, Germany.; Institute of Medical Genetics and Human Genetics, Charité - Universitätsmedizin Berlin, Augustenburger Platz 1, 13353 Berlin, Germany.
Gonzalez T; The Jackson Laboratory for Genomic Medicine, 10 Discovery Drive, Farmington, CT 06032, USA.; Harvey Mudd College, 301 Platt Boulevard, Claremont, CA 91711, USA.
Seelow D; Berlin Institute of Health, Charitéplatz 1, 10117 Berlin, Germany.; Institute of Medical Genetics and Human Genetics, Charité - Universitätsmedizin Berlin, Augustenburger Platz 1, 13353 Berlin, Germany.
Robinson PN; The Jackson Laboratory for Genomic Medicine, 10 Discovery Drive, Farmington, CT 06032, USA.; Institute for Systems Genomics, University of Connecticut, 263 Farmington Avenue, Farmington, CT 06030, USA.
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Źródło :
Nucleic acids research [Nucleic Acids Res] 2020 Jun 04; Vol. 48 (10), pp. 5306-5317.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
CpG Islands*
Enhancer Elements, Genetic*
Promoter Regions, Genetic*
Transcription, Genetic*
Gene Expression Regulation ; Histone Code ; Humans ; Organ Specificity ; TATA Box ; Transcription Factors/metabolism ; Transcription Initiation, Genetic
Czasopismo naukowe
Tytuł :
Characterization of histone modification patterns and prediction of novel promoters using functional principal component analysis.
Autorzy :
Kim M; Department of Statistics, Ewha Womans University, Seoul, Republic of Korea.
Lin S; Department of Statistics, Ohio State University, Columbus, Ohio, United States of America.
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Źródło :
PloS one [PLoS One] 2020 May 27; Vol. 15 (5), pp. e0233630. Date of Electronic Publication: 2020 May 27 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
CpG Islands*
Polymorphism, Single Nucleotide*
Promoter Regions, Genetic*
Protein Processing, Post-Translational*
Transcription, Genetic*
B-Lymphocytes/*metabolism
Histones/*metabolism
B-Lymphocytes/cytology ; Histones/genetics ; Humans
Czasopismo naukowe
Tytuł :
TFIID Enables RNA Polymerase II Promoter-Proximal Pausing.
Autorzy :
Fant CB; Department of Biochemistry, University of Colorado, Boulder, CO, USA.
Levandowski CB; Department of Biochemistry, University of Colorado, Boulder, CO, USA.
Gupta K; School of Biochemistry, Bristol Research Centre for Synthetic Biology, University of Bristol, Bristol, UK.
Maas ZL; Department of Biochemistry, University of Colorado, Boulder, CO, USA.
Moir J; Department of Biochemistry, University of Colorado, Boulder, CO, USA.
Rubin JD; Department of Biochemistry, University of Colorado, Boulder, CO, USA.
Sawyer A; Department of Biology, Brandeis University, Waltham, MA, USA.
Esbin MN; Department of Biochemistry, University of Colorado, Boulder, CO, USA.
Rimel JK; Department of Biochemistry, University of Colorado, Boulder, CO, USA.
Luyties O; Department of Biochemistry, University of Colorado, Boulder, CO, USA.
Marr MT; Department of Biology, Brandeis University, Waltham, MA, USA.
Berger I; School of Biochemistry, Bristol Research Centre for Synthetic Biology, University of Bristol, Bristol, UK.
Dowell RD; Department of Molecular, Cellular, and Developmental Biology, University of Colorado, Boulder, CO, USA; BioFrontiers Institute, University of Colorado, Boulder, CO, USA.
Taatjes DJ; Department of Biochemistry, University of Colorado, Boulder, CO, USA. Electronic address: .
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Źródło :
Molecular cell [Mol Cell] 2020 May 21; Vol. 78 (4), pp. 785-793.e8. Date of Electronic Publication: 2020 Mar 30.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Promoter Regions, Genetic*
Transcription, Genetic*
Drosophila/*metabolism
Drosophila Proteins/*metabolism
RNA Polymerase II/*genetics
Transcription Factor TFIID/*metabolism
Animals ; Drosophila/genetics ; Drosophila Proteins/genetics ; HCT116 Cells ; Humans ; Protein Binding ; RNA Polymerase II/metabolism ; Transcription Factor TFIID/genetics
Czasopismo naukowe
Tytuł :
Multiple weak interactions between BvgA~P and ptx promoter DNA strongly activate transcription of pertussis toxin genes in Bordetella pertussis.
Autorzy :
Chen Q; Division of Bacterial, Parasitic, and Allergenic Products, Center For Biologics Evaluation and Research, FDA, Silver Spring, Maryland, United States of America.
Boucher PE; Division of Bacterial, Parasitic, and Allergenic Products, Center For Biologics Evaluation and Research, FDA, Silver Spring, Maryland, United States of America.
Stibitz S; Division of Bacterial, Parasitic, and Allergenic Products, Center For Biologics Evaluation and Research, FDA, Silver Spring, Maryland, United States of America.
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Źródło :
PLoS pathogens [PLoS Pathog] 2020 May 13; Vol. 16 (5), pp. e1008500. Date of Electronic Publication: 2020 May 13 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Bacterial Proteins*/genetics
Bacterial Proteins*/metabolism
Bordetella pertussis*/genetics
Bordetella pertussis*/metabolism
DNA, Bacterial*/genetics
DNA, Bacterial*/metabolism
Pertussis Toxin*/biosynthesis
Pertussis Toxin*/genetics
Promoter Regions, Genetic*
Transcription Factors*/genetics
Transcription Factors*/metabolism
Transcription, Genetic*
Adhesins, Bacterial/biosynthesis ; Adhesins, Bacterial/genetics ; Gene Expression Regulation, Bacterial/physiology ; Virulence Factors, Bordetella/biosynthesis ; Virulence Factors, Bordetella/genetics
Czasopismo naukowe
Tytuł :
Visualizing the Role of Boundary Elements in Enhancer-Promoter Communication.
Autorzy :
Yokoshi M; Laboratory of Transcription Dynamics, Research Center for Biological Visualization, Institute for Quantitative Biosciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-0032, Japan.
Segawa K; Department of Bioinformatics and Systems Biology, Faculty of Science, The University of Tokyo, Bunkyo-ku, Tokyo 113-0032, Japan.
Fukaya T; Laboratory of Transcription Dynamics, Research Center for Biological Visualization, Institute for Quantitative Biosciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-0032, Japan; Department of Life Sciences, Graduate School of Arts and Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-0032, Japan. Electronic address: .
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Źródło :
Molecular cell [Mol Cell] 2020 Apr 16; Vol. 78 (2), pp. 224-235.e5. Date of Electronic Publication: 2020 Feb 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Enhancer Elements, Genetic*
Promoter Regions, Genetic*
Transcription, Genetic*
Embryonic Development/*genetics
Animals ; Chromosomes/genetics ; Drosophila/genetics ; Drosophila/growth & development ; Embryo, Nonmammalian
Czasopismo naukowe
Tytuł :
Identification of a transcriptional regulator for oligotrophy-responsive promoter in Rhodococcus erythropolis N9T-4.
Autorzy :
Ikegaya R; Applied Chemistry and Biochemical Engineering Course, Department of Engineering, Graduate School of Integrated Science and Technology, Shizuoka University, Hamamatsu, Japan.
Shintani M; Applied Chemistry and Biochemical Engineering Course, Department of Engineering, Graduate School of Integrated Science and Technology, Shizuoka University, Hamamatsu, Japan.
Kimbara K; Applied Chemistry and Biochemical Engineering Course, Department of Engineering, Graduate School of Integrated Science and Technology, Shizuoka University, Hamamatsu, Japan.
Fakuda
Yoshida N; Applied Chemistry and Biochemical Engineering Course, Department of Engineering, Graduate School of Integrated Science and Technology, Shizuoka University, Hamamatsu, Japan.
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Źródło :
Bioscience, biotechnology, and biochemistry [Biosci Biotechnol Biochem] 2020 Apr; Vol. 84 (4), pp. 865-868. Date of Electronic Publication: 2019 Dec 28.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation, Bacterial*
Promoter Regions, Genetic*
Transcription, Genetic*
Rhodococcus/*genetics
SCR Organism :
Rhodococcus erythropolis
Czasopismo naukowe
Tytuł :
Prion protein transcription is auto-regulated through dynamic interactions with G-quadruplex motifs in its own promoter.
Autorzy :
Pradhan P; Kusuma School of Biological Sciences, IIT Delhi, Hauz Khas, New Delhi 110016, India.
Srivastava A; Kusuma School of Biological Sciences, IIT Delhi, Hauz Khas, New Delhi 110016, India.
Singh J; Kusuma School of Biological Sciences, IIT Delhi, Hauz Khas, New Delhi 110016, India.
Biswas B; Kusuma School of Biological Sciences, IIT Delhi, Hauz Khas, New Delhi 110016, India.
Saini A; Kusuma School of Biological Sciences, IIT Delhi, Hauz Khas, New Delhi 110016, India.
Siddique I; National Institute of Immunology, Aruna Asaf Ali Marg, New Delhi 110067, India.
Kumari P; Transcription Regulation group, International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi 110067, India.
Khan MA; Department of Biochemistry, University of Delhi, South Campus, New Delhi 110021, India.
Mishra A; Kusuma School of Biological Sciences, IIT Delhi, Hauz Khas, New Delhi 110016, India.
Yadav PK; Kusuma School of Biological Sciences, IIT Delhi, Hauz Khas, New Delhi 110016, India.
Kumar S; Kusuma School of Biological Sciences, IIT Delhi, Hauz Khas, New Delhi 110016, India.
Bhavesh NS; Transcription Regulation group, International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi 110067, India.
Venkatraman P; Tata Memorial Centre, Advanced Centre for Treatment, Research and Education in Cancer, Kharghar, Navi Mumbai 410210, India; Homi Bhabha National Institute, 2nd floor, BARC Training School Complex, Anushaktinagar, Mumbai, Maharashtra 400094, India.
Vivekanandan P; Kusuma School of Biological Sciences, IIT Delhi, Hauz Khas, New Delhi 110016, India. Electronic address: .
Kundu B; Kusuma School of Biological Sciences, IIT Delhi, Hauz Khas, New Delhi 110016, India. Electronic address: .
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Źródło :
Biochimica et biophysica acta. Gene regulatory mechanisms [Biochim Biophys Acta Gene Regul Mech] 2020 Mar; Vol. 1863 (3), pp. 194479. Date of Electronic Publication: 2020 Jan 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
G-Quadruplexes*
Gene Expression Regulation*
Promoter Regions, Genetic*
Transcription, Genetic*
Prion Proteins/*genetics
Cells, Cultured ; Feedback, Physiological ; Humans ; Prion Proteins/biosynthesis ; Prion Proteins/chemistry ; Prion Proteins/metabolism
Czasopismo naukowe
Tytuł :
Characterization and Analysis of Mammalian AKR7A Gene Promoters: Implications for Transcriptional Regulation.
Autorzy :
Rajib SA; Department of Pharmacy, Brac University, 41, Pacific Tower, Mohakhali, Dhaka, 1212, Bangladesh. .
Sharif Siam MK; Department of Pharmacy, Brac University, 41, Pacific Tower, Mohakhali, Dhaka, 1212, Bangladesh.; Darwin College, University of Cambridge, Silver Street, Cambridge, CB3 9EU, UK.
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Źródło :
Biochemical genetics [Biochem Genet] 2020 Feb; Vol. 58 (1), pp. 171-188. Date of Electronic Publication: 2019 Sep 16.
Typ publikacji :
Comparative Study; Journal Article; Review
MeSH Terms :
Gene Expression Regulation*
Transcription, Genetic*
Aldo-Keto Reductases/*genetics
Promoter Regions, Genetic/*genetics
Amino Acid Sequence ; Animals ; Base Sequence/genetics ; Binding Sites/genetics ; Databases, Genetic ; Humans ; Mice ; Rats
Czasopismo naukowe
Tytuł :
Interaction between CA repeat microsatellites and HIF1α regulated the transcriptional activity of porcine IGF1 promoter.
Autorzy :
Geng H; College of Animal Science, Jilin University, 5333 Xi'an Road, Changchun, 130062, Jilin, China.
Hao L; College of Animal Science, Jilin University, 5333 Xi'an Road, Changchun, 130062, Jilin, China.
Cheng Y; College of Animal Science, Jilin University, 5333 Xi'an Road, Changchun, 130062, Jilin, China.
Wang C; College of Animal Science, Jilin University, 5333 Xi'an Road, Changchun, 130062, Jilin, China.
Huang S; College of Animal Science, Jilin University, 5333 Xi'an Road, Changchun, 130062, Jilin, China.
Wei W; College of Animal Science, Jilin University, 5333 Xi'an Road, Changchun, 130062, Jilin, China.
Yang R; College of Animal Science, Jilin University, 5333 Xi'an Road, Changchun, 130062, Jilin, China.
Li H; College of Animal Science, Jilin University, 5333 Xi'an Road, Changchun, 130062, Jilin, China.
Liu S; College of Animal Science, Jilin University, 5333 Xi'an Road, Changchun, 130062, Jilin, China. .; Five-Star Animal Health Pharmaceutical Factory of Jilin Province, Changchun, Jilin, 130062, China. .
Yu H; College of Animal Science, Jilin University, 5333 Xi'an Road, Changchun, 130062, Jilin, China. .
Lu H; The Second Hospital of Jilin University, 218 Ziqiang Street, Changchun, Jilin, 130041, China. .
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Źródło :
Journal of applied genetics [J Appl Genet] 2020 Feb; Vol. 61 (1), pp. 105-112. Date of Electronic Publication: 2019 Nov 01.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation*
Microsatellite Repeats*
Promoter Regions, Genetic*
Transcription, Genetic*
Hypoxia-Inducible Factor 1, alpha Subunit/*metabolism
Insulin-Like Growth Factor I/*genetics
Animals ; Binding Sites ; Cells, Cultured ; Polymorphism, Genetic ; Protein Binding ; Swine
Czasopismo naukowe
Tytuł :
sRNA EsrE Is Transcriptionally Regulated by the Ferric Uptake Regulator Fur in Escherichia coli .
Autorzy :
Hou B; State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, P.R. China.; Department of Applied Biology, East China University of Science and Technology, Shanghai, P.R. China.
Yang X; State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, P.R. China.
Xia H; State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, P.R. China.
Wu H; State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, P.R. China.; Department of Applied Biology, East China University of Science and Technology, Shanghai, P.R. China.
Ye J; State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, P.R. China.; Department of Applied Biology, East China University of Science and Technology, Shanghai, P.R. China.
Zhang H; State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, P.R. China.; Department of Applied Biology, East China University of Science and Technology, Shanghai, P.R. China.
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Źródło :
Journal of microbiology and biotechnology [J Microbiol Biotechnol] 2020 Jan 28; Vol. 30 (1), pp. 127-135.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation, Bacterial*
Promoter Regions, Genetic*
Transcription, Genetic*
Bacterial Proteins/*genetics
Escherichia coli/*genetics
RNA, Bacterial/*genetics
Repressor Proteins/*genetics
Czasopismo naukowe
Tytuł :
Dual-initiation promoters with intertwined canonical and TCT/TOP transcription start sites diversify transcript processing.
Autorzy :
Nepal C; Biotech Research and Innovation Centre, Department of Health and Medical Sciences, University of Copenhagen, Ole Maaloes Vej 5, 2200, Copenhagen, Denmark. .
Hadzhiev Y; Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
Balwierz P; Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.; Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, W12 0NN, London, UK.; MRC Clinical Sciences Centre, Hammersmith Hospital Campus, W12 0NN, London, UK.
Tarifeño-Saldivia E; Laboratory for Molecular Biology and Genetic Engineering, GIGA-R, Université de Liège, Liège, Belgium.; Department of Biochemistry and Molecular Biology, Faculty of Biological Sciences, University of Concepcion, Concepción, Chile.
Cardenas R; Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
Wragg JW; Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
Suzuki AM; Division of Genomic Technologies, RIKEN Center for Life Science Technologies, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, 230-0045, Japan.
Carninci P; Division of Genomic Technologies, RIKEN Center for Life Science Technologies, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, 230-0045, Japan.; Laboratory for Transcriptome Technology, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, 230-0045, Japan.
Peers B; Laboratory for Molecular Biology and Genetic Engineering, GIGA-R, Université de Liège, Liège, Belgium.
Lenhard B; Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, W12 0NN, London, UK.; MRC Clinical Sciences Centre, Hammersmith Hospital Campus, W12 0NN, London, UK.
Andersen JB; Biotech Research and Innovation Centre, Department of Health and Medical Sciences, University of Copenhagen, Ole Maaloes Vej 5, 2200, Copenhagen, Denmark.
Müller F; Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK. .
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Źródło :
Nature communications [Nat Commun] 2020 Jan 10; Vol. 11 (1), pp. 168. Date of Electronic Publication: 2020 Jan 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation, Developmental*
Gene Regulatory Networks*
Transcription Initiation Site*
Transcription, Genetic*
Promoter Regions, Genetic/*genetics
Animals ; Base Sequence ; Drosophila/genetics ; Drosophila/growth & development ; Humans ; RNA/genetics ; RNA/physiology ; RNA, Small Nucleolar/genetics ; RNA, Small Nucleolar/metabolism ; RNA, Small Untranslated/genetics ; RNA, Small Untranslated/physiology ; RNA, Untranslated/genetics ; RNA, Untranslated/physiology ; Regulatory Elements, Transcriptional ; Zebrafish/genetics ; Zebrafish/growth & development ; Zygote
Czasopismo naukowe
Tytuł :
Multiple domains in the 50 kDa form of E4F1 regulate promoter-specific repression and E1A trans-activation.
Autorzy :
Rooney RJ; Department of Genetics, Duke University Medical Center, Durham, NC, USA. Electronic address: .
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Źródło :
Gene [Gene] 2020 Sep 05; Vol. 754, pp. 144882. Date of Electronic Publication: 2020 Jun 11.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation*
Promoter Regions, Genetic*
Transcriptional Activation*
Adenovirus E1A Proteins/*genetics
Repressor Proteins/*metabolism
Ubiquitin-Protein Ligases/*metabolism
Adenovirus E1A Proteins/metabolism ; Binding Sites ; HEK293 Cells ; HeLa Cells ; Humans ; Phosphorylation ; Protein Domains ; Repressor Proteins/genetics ; Transcription, Genetic ; Ubiquitin-Protein Ligases/genetics
Czasopismo naukowe
Tytuł :
XACT-Seq Comprehensively Defines the Promoter-Position and Promoter-Sequence Determinants for Initial-Transcription Pausing.
Autorzy :
Winkelman JT; Department of Genetics, Rutgers University, Piscataway, NJ 08854, USA; Department of Chemistry and Chemical Biology, Rutgers University, Piscataway, NJ 08854, USA; Waksman Institute, Rutgers University, Piscataway, NJ 08854, USA.
Pukhrambam C; Department of Genetics, Rutgers University, Piscataway, NJ 08854, USA; Waksman Institute, Rutgers University, Piscataway, NJ 08854, USA.
Vvedenskaya IO; Department of Genetics, Rutgers University, Piscataway, NJ 08854, USA; Waksman Institute, Rutgers University, Piscataway, NJ 08854, USA.
Zhang Y; Department of Genetics, Rutgers University, Piscataway, NJ 08854, USA; Department of Biomedical and Health Informatics, The Children's Hospital of Philadelphia, Philadelphia, PA 19041, USA.
Taylor DM; Department of Biomedical and Health Informatics, The Children's Hospital of Philadelphia, Philadelphia, PA 19041, USA; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Shah P; Department of Genetics, Rutgers University, Piscataway, NJ 08854, USA.
Ebright RH; Department of Chemistry and Chemical Biology, Rutgers University, Piscataway, NJ 08854, USA; Waksman Institute, Rutgers University, Piscataway, NJ 08854, USA. Electronic address: .
Nickels BE; Department of Genetics, Rutgers University, Piscataway, NJ 08854, USA; Waksman Institute, Rutgers University, Piscataway, NJ 08854, USA. Electronic address: .
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Źródło :
Molecular cell [Mol Cell] 2020 Sep 03; Vol. 79 (5), pp. 797-811.e8. Date of Electronic Publication: 2020 Aug 03.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Promoter Regions, Genetic*
DNA, Bacterial/*metabolism
DNA-Directed RNA Polymerases/*metabolism
Sequence Analysis, DNA/*methods
Catalytic Domain ; Escherichia coli/genetics ; Escherichia coli Proteins/metabolism ; Gene Expression Regulation, Bacterial ; Transcription, Genetic
Czasopismo naukowe
Tytuł :
A unified view of the sequence and functional organization of the human RNA polymerase II promoter.
Autorzy :
Luse DS; Department of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA.
Parida M; Department of Biochemistry, The University of Iowa, Iowa City, IA 52242, USA.
Spector BM; Department of Biochemistry, The University of Iowa, Iowa City, IA 52242, USA.
Nilson KA; Department of Biochemistry, The University of Iowa, Iowa City, IA 52242, USA.
Price DH; Department of Biochemistry, The University of Iowa, Iowa City, IA 52242, USA.
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Źródło :
Nucleic acids research [Nucleic Acids Res] 2020 Aug 20; Vol. 48 (14), pp. 7767-7785.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Promoter Regions, Genetic*
RNA Polymerase II/*metabolism
Base Sequence ; DNA/chemistry ; HeLa Cells ; Humans ; Methylation ; Nucleosomes ; RNA Caps/metabolism ; Transcription Factor TFIID/metabolism ; Transcription Initiation Site ; Transcription, Genetic
Czasopismo naukowe
Tytuł :
Understanding the interplay between CpG island-associated gene promoters and H3K4 methylation.
Autorzy :
Hughes AL; Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, United Kingdom.
Kelley JR; Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, United Kingdom.
Klose RJ; Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, United Kingdom. Electronic address: .
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Źródło :
Biochimica et biophysica acta. Gene regulatory mechanisms [Biochim Biophys Acta Gene Regul Mech] 2020 Aug; Vol. 1863 (8), pp. 194567. Date of Electronic Publication: 2020 Apr 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Promoter Regions, Genetic*
Protein Processing, Post-Translational*
CpG Islands/*genetics
Histones/*genetics
Histones/*metabolism
Animals ; Chromatin ; DNA Methylation ; DNA-Binding Proteins ; Gene Expression Regulation ; Histone-Lysine N-Methyltransferase ; Myeloid-Lymphoid Leukemia Protein ; Neoplasm Proteins ; Transcription, Genetic
Czasopismo naukowe
Tytuł :
Molecular insight into RNA polymerase I promoter recognition and promoter melting.
Autorzy :
Sadian Y; European Molecular Biology Laboratory (EMBL), Structural and Computational Biology Unit, Meyerhofstrasse 1, 69117, Heidelberg, Germany.; Bioimaging Center, University of Geneva, 30, Quai Ernest-Ansermet 4, CH-1211, Geneva, Switzerland.
Baudin F; European Molecular Biology Laboratory (EMBL), Structural and Computational Biology Unit, Meyerhofstrasse 1, 69117, Heidelberg, Germany.
Tafur L; European Molecular Biology Laboratory (EMBL), Structural and Computational Biology Unit, Meyerhofstrasse 1, 69117, Heidelberg, Germany.; Collaboration for joint PhD degree between EMBL and Heidelberg University, Faculty of Biosciences, 69120, Heidelberg, Germany.; Department of Molecular Biology, University of Geneva Sciences III, 30, Quai Ernest-Ansermet 4, CH-1211, Geneva, Switzerland.
Murciano B; European Molecular Biology Laboratory (EMBL), Structural and Computational Biology Unit, Meyerhofstrasse 1, 69117, Heidelberg, Germany.
Wetzel R; European Molecular Biology Laboratory (EMBL), Structural and Computational Biology Unit, Meyerhofstrasse 1, 69117, Heidelberg, Germany.
Weis F; European Molecular Biology Laboratory (EMBL), Structural and Computational Biology Unit, Meyerhofstrasse 1, 69117, Heidelberg, Germany.
Müller CW; European Molecular Biology Laboratory (EMBL), Structural and Computational Biology Unit, Meyerhofstrasse 1, 69117, Heidelberg, Germany. .
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Źródło :
Nature communications [Nat Commun] 2019 Dec 05; Vol. 10 (1), pp. 5543. Date of Electronic Publication: 2019 Dec 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Transcription, Genetic*
DNA, Fungal/*genetics
Promoter Regions, Genetic/*genetics
RNA Polymerase I/*genetics
Saccharomyces cerevisiae/*genetics
Saccharomyces cerevisiae Proteins/*genetics
Binding Sites/genetics ; Cryoelectron Microscopy ; DNA, Fungal/chemistry ; DNA, Fungal/metabolism ; Models, Molecular ; Nucleic Acid Conformation ; Protein Binding ; Protein Domains ; RNA Polymerase I/chemistry ; RNA Polymerase I/metabolism ; RNA Polymerase II/chemistry ; RNA Polymerase II/genetics ; RNA Polymerase II/metabolism ; Saccharomyces cerevisiae/metabolism ; Saccharomyces cerevisiae/ultrastructure ; Saccharomyces cerevisiae Proteins/chemistry ; Saccharomyces cerevisiae Proteins/metabolism ; Transcription Initiation, Genetic
Czasopismo naukowe

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