Temat: "Transcription, Genetic" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Transcriptional neighborhoods regulate transcript isoform lengths and expression levels.
Autorzy:: Brooks AN; European Molecular Biology Laboratory (EMBL), Genome Biology Unit, 69117 Heidelberg, Germany.
Hughes AL; European Molecular Biology Laboratory (EMBL), Genome Biology Unit, 69117 Heidelberg, Germany.
Clauder-Münster S; European Molecular Biology Laboratory (EMBL), Genome Biology Unit, 69117 Heidelberg, Germany.
Mitchell LA; Institute for Systems Genetics and Department of Biochemistry and Molecular Pharmacology, NYU Langone Health, New York, NY 10016, USA.
Boeke JD; Institute for Systems Genetics and Department of Biochemistry and Molecular Pharmacology, NYU Langone Health, New York, NY 10016, USA.; Department of Biomedical Engineering, NYU Tandon School of Engineering, Brooklyn, NY 11201, USA.
Steinmetz LM; European Molecular Biology Laboratory (EMBL), Genome Biology Unit, 69117 Heidelberg, Germany.; Stanford Genome Technology Center, Stanford University, Palo Alto, CA 94304, USA.; Department of Genetics, School of Medicine, Stanford University, Stanford, CA 94305, USA.; Pokaż więcej
Źródło:: Science (New York, N.Y.) [Science] 2022 Mar 04; Vol. 375 (6584), pp. 1000-1005. Date of Electronic Publication: 2022 Mar 03.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Genome, Fungal*
Transcription, Genetic*
Transcriptome*
RNA, Fungal/*genetics
RNA, Messenger/*genetics
Saccharomyces cerevisiae/*genetics
3' Untranslated Regions ; Base Sequence ; Gene Rearrangement ; Genetic Variation ; RNA, Fungal/chemistry ; RNA, Fungal/metabolism ; RNA, Messenger/chemistry ; RNA, Messenger/metabolism ; RNA-Seq ; Sequence Analysis, RNA

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Skocz do pozycji: 2.

Tytuł:: Principles of gene regulation quantitatively connect DNA to RNA and proteins in bacteria.
Autorzy:: Balakrishnan R; Department of Physics, University of California at San Diego, La Jolla, CA 92093, USA.
Mori M; Department of Physics, University of California at San Diego, La Jolla, CA 92093, USA.
Segota I; Departments of Medicine and Pharmacology, University of California at San Diego, La Jolla, CA 92093, USA.
Zhang Z; Section of Molecular Biology, Division of Biological Sciences, University of California at San Diego, La Jolla, CA 92093, USA.
Aebersold R; Faculty of Science, University of Zurich, Zürich, Switzerland.; Department of Biology, Institute of Molecular Systems Biology, ETH Zurich, Zürich, Switzerland.
Ludwig C; Bavarian Center for Biomolecular Mass Spectrometry (BayBioMS), Technical University of Munich (TUM), Freising, Germany.
Hwa T; Department of Physics, University of California at San Diego, La Jolla, CA 92093, USA.; Section of Molecular Biology, Division of Biological Sciences, University of California at San Diego, La Jolla, CA 92093, USA.; Pokaż więcej
Źródło:: Science (New York, N.Y.) [Science] 2022 Dec 09; Vol. 378 (6624), pp. eabk2066. Date of Electronic Publication: 2022 Dec 09.
Typ publikacji:: Journal Article
MeSH Terms:: Gene Expression Regulation, Bacterial*
Protein Biosynthesis*/genetics
Escherichia coli*/genetics
RNA, Messenger*/genetics
RNA, Messenger*/metabolism
RNA, Bacterial/genetics ; DNA, Bacterial/genetics ; Promoter Regions, Genetic ; Transcription, Genetic

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Skocz do pozycji: 3.

Tytuł:: Polyadenylation-related isoform switching in human evolution revealed by full-length transcript structure.
Autorzy:: Li Y; Laboratory of Bioinformatics and Genomic Medicine, Institute of Molecular Medicine, Peking University, Beijing, China.
Shen QS; Laboratory of Bioinformatics and Genomic Medicine, Institute of Molecular Medicine, Peking University, Beijing, China.
Peng Q; Laboratory of Bioinformatics and Genomic Medicine, Institute of Molecular Medicine, Peking University, Beijing, China.; College of Future Technology, Peking University, Beijing, China.
Ding W; Laboratory of Bioinformatics and Genomic Medicine, Institute of Molecular Medicine, Peking University, Beijing, China.; College of Future Technology, Peking University, Beijing, China.
Zhang J; Laboratory of Bioinformatics and Genomic Medicine, Institute of Molecular Medicine, Peking University, Beijing, China.; College of Future Technology, Peking University, Beijing, China.
Zhong X; Laboratory of Bioinformatics and Genomic Medicine, Institute of Molecular Medicine, Peking University, Beijing, China.
An NA; Laboratory of Bioinformatics and Genomic Medicine, Institute of Molecular Medicine, Peking University, Beijing, China.; College of Future Technology, Peking University, Beijing, China.
Ji M; Laboratory of Bioinformatics and Genomic Medicine, Institute of Molecular Medicine, Peking University, Beijing, China.; College of Future Technology, Peking University, Beijing, China.
Zhou WZ; State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, Beijing, China.
Li CY; Laboratory of Bioinformatics and Genomic Medicine, Institute of Molecular Medicine, Peking University, Beijing, China.; College of Future Technology, Peking University, Beijing, China.; Pokaż więcej
Źródło:: Briefings in bioinformatics [Brief Bioinform] 2021 Nov 05; Vol. 22 (6).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Evolution, Molecular*
Poly A*
Polyadenylation*
RNA Isoforms*
Transcription, Genetic*
RNA, Messenger/*chemistry
RNA, Messenger/*genetics
3' Untranslated Regions ; Animals ; Gene Expression Profiling ; Gene Expression Regulation ; Humans ; Macaca mulatta ; Models, Genetic ; Nucleotide Motifs ; Organ Specificity ; RNA Transport ; Species Specificity ; Transcriptome

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Skocz do pozycji: 4.

Tytuł:: Advances in the Bioinformatics Knowledge of mRNA Polyadenylation in Baculovirus Genes.
Autorzy:: Peros IG; Laboratorio de Ingeniería Genética y Biología Celular y Molecular-Área Virosis de Invertebrados, Departamento de Ciencia y Tecnología, Instituto de Microbiología Básica y Aplicada, Universidad Nacional de Quilmes, Roque Sáenz Peña 352, B1876BXD Bernal, Buenos Aires, Argentina.
Cerrudo CS; Laboratorio de Ingeniería Genética y Biología Celular y Molecular-Área Virosis de Invertebrados, Departamento de Ciencia y Tecnología, Instituto de Microbiología Básica y Aplicada, Universidad Nacional de Quilmes, Roque Sáenz Peña 352, B1876BXD Bernal, Buenos Aires, Argentina.
Pilloff MG; Laboratorio de Virus Emergentes, Departamento de Ciencia y Tecnología, Instituto de Microbiología Básica y Aplicada, Universidad Nacional de Quilmes, Roque Sáenz Peña 352, B1876BXD Bernal, Buenos Aires, Argentina.
Belaich MN; Laboratorio de Ingeniería Genética y Biología Celular y Molecular-Área Virosis de Invertebrados, Departamento de Ciencia y Tecnología, Instituto de Microbiología Básica y Aplicada, Universidad Nacional de Quilmes, Roque Sáenz Peña 352, B1876BXD Bernal, Buenos Aires, Argentina.
Lozano ME; Laboratorio de Virus Emergentes, Departamento de Ciencia y Tecnología, Instituto de Microbiología Básica y Aplicada, Universidad Nacional de Quilmes, Roque Sáenz Peña 352, B1876BXD Bernal, Buenos Aires, Argentina.
Ghiringhelli PD; Laboratorio de Ingeniería Genética y Biología Celular y Molecular-Área Virosis de Invertebrados, Departamento de Ciencia y Tecnología, Instituto de Microbiología Básica y Aplicada, Universidad Nacional de Quilmes, Roque Sáenz Peña 352, B1876BXD Bernal, Buenos Aires, Argentina.; Pokaż więcej
Źródło:: Viruses [Viruses] 2020 Dec 06; Vol. 12 (12). Date of Electronic Publication: 2020 Dec 06.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:: Gene Expression Regulation, Viral*
Polyadenylation*
Transcription, Genetic*
Baculoviridae/*genetics
Insect Viruses/*genetics
RNA, Messenger/*genetics
3' Untranslated Regions ; Animals ; Baculoviridae/metabolism ; Binding Sites ; Genome, Viral ; Genomics/methods ; Protein Binding ; RNA Processing, Post-Transcriptional ; Regulatory Sequences, Ribonucleic Acid ; Virus Replication

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Skocz do pozycji: 5.

Tytuł:: sRNA-mediated regulation of gal mRNA in E. coli: Involvement of transcript cleavage by RNase E together with Rho-dependent transcription termination.
Autorzy:: Jeon HJ; Department of Biological Sciences, College of Biological Sciences and Biotechnology, Chungnam National University, Daejeon, Republic of Korea.; Infection Control Convergence Research Center, College of Medicine, Chungnam National University, Daejeon, Republic of Korea.
Lee Y; Department of Biological Sciences, College of Biological Sciences and Biotechnology, Chungnam National University, Daejeon, Republic of Korea.
N MPA; Department of Biological Sciences, College of Biological Sciences and Biotechnology, Chungnam National University, Daejeon, Republic of Korea.
Wang X; State Key Laboratory of Agricultural Microbiology, College of Life Science and Technology, Huazhong Agricultural University, Wuhan, PR China.
Chattoraj DK; Basic Research Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America.
Lim HM; Department of Biological Sciences, College of Biological Sciences and Biotechnology, Chungnam National University, Daejeon, Republic of Korea.; Pokaż więcej
Źródło:: PLoS genetics [PLoS Genet] 2021 Oct 28; Vol. 17 (10), pp. e1009878. Date of Electronic Publication: 2021 Oct 28 (Print Publication: 2021).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Endoribonucleases/*genetics
Escherichia coli/*genetics
RNA, Messenger/*genetics
RNA, Small Untranslated/*genetics
Transcription Termination, Genetic/*physiology
Transcription, Genetic/*genetics
Escherichia coli Proteins/genetics ; Gene Expression Regulation, Bacterial/genetics ; Operon/genetics ; RNA, Bacterial/genetics

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Skocz do pozycji: 6.

Tytuł:: The cap-specific m6A methyltransferase, PCIF1/CAPAM, is dynamically recruited to the gene promoter in a transcription-dependent manner.
Autorzy:: Sugita A; Laboratory of Gene Regulation, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, 2630 Sugitani, Toyama 930-0194, Japan.
Kuruma S; Laboratory of Gene Regulation, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, 2630 Sugitani, Toyama 930-0194, Japan.
Yanagisawa N; Laboratory of Gene Regulation, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, 2630 Sugitani, Toyama 930-0194, Japan.
Ishiguro H; Laboratory of Gene Regulation, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, 2630 Sugitani, Toyama 930-0194, Japan.
Kano R; Laboratory of Gene Regulation, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, 2630 Sugitani, Toyama 930-0194, Japan.
Ohkuma Y; Laboratory of Gene Regulation, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, 2630 Sugitani, Toyama 930-0194, Japan.; Department of Biochemistry, Graduate School of Biomedical Sciences, Nagasaki University, 1-12-4 Sakamoto, Nagasaki 852-8523, Japan.
Hirose Y; Laboratory of Gene Regulation, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, 2630 Sugitani, Toyama 930-0194, Japan.; Pokaż więcej
Źródło:: Journal of biochemistry [J Biochem] 2021 Oct 11; Vol. 170 (2), pp. 203-213.
Typ publikacji:: Journal Article
MeSH Terms:: Adaptor Proteins, Signal Transducing/*metabolism
Adenosine/*analogs & derivatives
Methyltransferases/*metabolism
Nuclear Proteins/*metabolism
RNA, Messenger/*metabolism
Adaptor Proteins, Signal Transducing/genetics ; Adenosine/genetics ; Adenosine/metabolism ; Chromatin/metabolism ; HeLa Cells ; Humans ; Methylation ; Methyltransferases/genetics ; Nuclear Proteins/genetics ; Phosphorylation ; Promoter Regions, Genetic ; Protein Transport ; RNA Polymerase II/metabolism ; RNA, Messenger/genetics ; Transcription, Genetic

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Skocz do pozycji: 7.

Tytuł:: Circadian rhythm shows potential for mRNA efficiency and self-organized division of labor in multinucleate cells.
Autorzy:: Zinn-Brooks L; Department of Mathematics, Harvey Mudd College, Claremont, California, United States of America.
Roper ML; Department of Mathematics, UCLA, Los Angeles, California, United States of America.; Pokaż więcej
Źródło:: PLoS computational biology [PLoS Comput Biol] 2021 Aug 02; Vol. 17 (8), pp. e1008828. Date of Electronic Publication: 2021 Aug 02 (Print Publication: 2021).
Typ publikacji:: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:: Models, Biological*
Circadian Rhythm/*genetics
Circadian Rhythm/*physiology
RNA, Messenger/*genetics
RNA, Messenger/*metabolism
Algorithms ; Animals ; Cell Nucleus/genetics ; Cell Nucleus/metabolism ; Computational Biology ; Computer Simulation ; Cytoplasm/genetics ; Cytoplasm/metabolism ; Giant Cells/cytology ; Giant Cells/metabolism ; Humans ; Models, Genetic ; Neurospora crassa/cytology ; Neurospora crassa/genetics ; Neurospora crassa/physiology ; RNA, Fungal/genetics ; RNA, Fungal/metabolism ; Stochastic Processes ; Transcription, Genetic

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Skocz do pozycji: 8.

Tytuł:: Fluorometric determination of agrA gene transcription in methicillin-resistant Staphylococcus aureus with a graphene oxide-based assay using strand-displacement polymerization recycling and hybridization chain reaction.
Autorzy:: Ning Y; Department of Microbiology, The Medicine School of Hunan University of Chinese Medicine, Changsha, 410208, Hunan, People's Republic of China.
Chen S; Department of General Education, The School of Humanities and Social Science, The Chinese University of Hong Kong (Shenzhen campus), Shenzhen, 518172, Guangdong, People's Republic of China.
Hu J; Department of Microbiology, The Medicine School of Hunan University of Chinese Medicine, Changsha, 410208, Hunan, People's Republic of China.
Li L; Experimental Center of molecular biology, The Chinese Medicine School of Hunan University of Chinese Medicine, Changsha, 410208, Hunan, People's Republic of China.
Cheng L; Department of Microbiology, The Medicine School of Hunan University of Chinese Medicine, Changsha, 410208, Hunan, People's Republic of China.
Lu F; Department of Microbiology, The Medicine School of Hunan University of Chinese Medicine, Changsha, 410208, Hunan, People's Republic of China. .; Pokaż więcej
Źródło:: Mikrochimica acta [Mikrochim Acta] 2020 Jun 05; Vol. 187 (7), pp. 372. Date of Electronic Publication: 2020 Jun 05.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Transcription, Genetic*
Bacterial Proteins/*genetics
Biological Assay/*methods
Graphite/*chemistry
RNA, Bacterial/*analysis
RNA, Messenger/*analysis
DNA/chemistry ; DNA/genetics ; DNA Probes/chemistry ; DNA Probes/genetics ; Fluoresceins/chemistry ; Fluorescent Dyes/chemistry ; Limit of Detection ; Methicillin-Resistant Staphylococcus aureus ; Nucleic Acid Hybridization ; RNA, Messenger/genetics ; Spectrometry, Fluorescence/methods

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Skocz do pozycji: 9.

Tytuł:: A model explaining mRNA level fluctuations based on activity demands and RNA age.
Autorzy:: Xu Z; Department of Ecology, Jinan University, Guangzhou, China.; Department of Aquatic Bioscience, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan.
Asakawa S; Department of Aquatic Bioscience, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan.; Pokaż więcej
Źródło:: PLoS computational biology [PLoS Comput Biol] 2021 Jul 23; Vol. 17 (7), pp. e1009188. Date of Electronic Publication: 2021 Jul 23 (Print Publication: 2021).
Typ publikacji:: Journal Article
MeSH Terms:: Models, Biological*
RNA Stability*/genetics
RNA Stability*/physiology
RNA, Messenger/*metabolism
Computational Biology ; Computer Simulation ; RNA, Fungal/genetics ; RNA, Fungal/metabolism ; RNA, Messenger/genetics ; Saccharomyces cerevisiae/cytology ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae/metabolism ; Saccharomyces cerevisiae Proteins/genetics ; Saccharomyces cerevisiae Proteins/metabolism ; Single-Cell Analysis ; Transcription, Genetic ; Transcriptome

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Skocz do pozycji: 10.

Tytuł:: Reprogramming mRNA Expression in Response to Defect in RNA Polymerase III Assembly in the Yeast Saccharomyces cerevisiae .
Autorzy:: Rudzińska I; Laboratory of tRNA Transcription, Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Pawińskiego 5A, 02-106 Warsaw, Poland.
Cieśla M; Laboratory of tRNA Transcription, Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Pawińskiego 5A, 02-106 Warsaw, Poland.
Turowski TW; Laboratory of tRNA Transcription, Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Pawińskiego 5A, 02-106 Warsaw, Poland.; Wellcome Centre for Cell Biology, The University of Edinburgh, Edinburgh EH8 9YL, UK.
Armatowska A; Laboratory of tRNA Transcription, Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Pawińskiego 5A, 02-106 Warsaw, Poland.
Leśniewska E; Laboratory of tRNA Transcription, Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Pawińskiego 5A, 02-106 Warsaw, Poland.
Boguta M; Laboratory of tRNA Transcription, Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Pawińskiego 5A, 02-106 Warsaw, Poland.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 Jul 07; Vol. 22 (14). Date of Electronic Publication: 2021 Jul 07.
Typ publikacji:: Journal Article
MeSH Terms:: RNA Polymerase III/*genetics
RNA, Messenger/*genetics
Saccharomyces cerevisiae/*genetics
DNA-Directed RNA Polymerases/genetics ; Down-Regulation/genetics ; Gene Expression Regulation, Fungal/genetics ; Humans ; RNA Polymerase II/genetics ; RNA, Transfer/genetics ; Saccharomyces cerevisiae Proteins/genetics ; Transcription Factors/genetics ; Transcription, Genetic/genetics ; Transcriptional Activation/genetics ; Transcriptome/genetics ; Up-Regulation/genetics

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Skocz do pozycji: 11.

Tytuł:: Visualization and modeling of inhibition of IL-1β and TNF-α mRNA transcription at the single-cell level.
Autorzy:: Kalb D; Center for Integrated Nanotechnologies, Los Alamos National Laboratory, Los Alamos, NM, USA.
Vo HD; Department of Chemical and Biological Engineering, Colorado State University, Fort Collins, CO, USA.
Adikari S; Bioscience Division, Los Alamos National Laboratory, Los Alamos, NM, USA.
Hong-Geller E; Bioscience Division, Los Alamos National Laboratory, Los Alamos, NM, USA.
Munsky B; Department of Chemical and Biological Engineering, Colorado State University, Fort Collins, CO, USA. .
Werner J; Center for Integrated Nanotechnologies, Los Alamos National Laboratory, Los Alamos, NM, USA. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2021 Jul 01; Vol. 11 (1), pp. 13692. Date of Electronic Publication: 2021 Jul 01.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:: Interleukin-1beta/*genetics
RNA, Messenger/*genetics
Tumor Necrosis Factor-alpha/*genetics
Gene Expression Regulation, Leukemic ; Humans ; Leukemia/genetics ; Single-Cell Analysis ; Transcription, Genetic ; Transcriptional Activation

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Skocz do pozycji: 12.

Tytuł:: Rapidly Growing Protein-Centric Technologies to Extensively Identify Protein-RNA Interactions: Application to the Analysis of Co-Transcriptional RNA Processing.
Autorzy:: Masuda A; Center for Neurological Diseases and Cancer, Division of Neurogenetics, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan.
Kawachi T; Center for Neurological Diseases and Cancer, Division of Neurogenetics, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan.
Ohno K; Center for Neurological Diseases and Cancer, Division of Neurogenetics, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 May 18; Vol. 22 (10). Date of Electronic Publication: 2021 May 18.
Typ publikacji:: Journal Article; Review
MeSH Terms:: RNA Processing, Post-Transcriptional*
Immunoprecipitation/*methods
RNA, Messenger/*genetics
RNA, Messenger/*metabolism
RNA-Binding Proteins/*metabolism
Binding Sites ; Gene Expression Profiling ; Humans ; Immunoprecipitation/trends ; Protein Binding ; RNA Polymerase II/metabolism ; Transcription, Genetic ; Transcriptome

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Skocz do pozycji: 13.

Tytuł:: Sequencing metabolically labeled transcripts in single cells reveals mRNA turnover strategies.
Autorzy:: Battich N; Oncode Institute, Hubrecht Institute-KNAW (Royal Netherlands Academy of Arts and Sciences) and University Medical Center Utrecht, 3584 CT Utrecht, Netherlands. .
Beumer J; Oncode Institute, Hubrecht Institute-KNAW (Royal Netherlands Academy of Arts and Sciences) and University Medical Center Utrecht, 3584 CT Utrecht, Netherlands.
de Barbanson B; Oncode Institute, Hubrecht Institute-KNAW (Royal Netherlands Academy of Arts and Sciences) and University Medical Center Utrecht, 3584 CT Utrecht, Netherlands.
Krenning L; Oncode Institute, Hubrecht Institute-KNAW (Royal Netherlands Academy of Arts and Sciences) and University Medical Center Utrecht, 3584 CT Utrecht, Netherlands.
Baron CS; Oncode Institute, Hubrecht Institute-KNAW (Royal Netherlands Academy of Arts and Sciences) and University Medical Center Utrecht, 3584 CT Utrecht, Netherlands.
Tanenbaum ME; Oncode Institute, Hubrecht Institute-KNAW (Royal Netherlands Academy of Arts and Sciences) and University Medical Center Utrecht, 3584 CT Utrecht, Netherlands.
Clevers H; Oncode Institute, Hubrecht Institute-KNAW (Royal Netherlands Academy of Arts and Sciences) and University Medical Center Utrecht, 3584 CT Utrecht, Netherlands.
van Oudenaarden A; Oncode Institute, Hubrecht Institute-KNAW (Royal Netherlands Academy of Arts and Sciences) and University Medical Center Utrecht, 3584 CT Utrecht, Netherlands. .; Pokaż więcej
Źródło:: Science (New York, N.Y.) [Science] 2020 Mar 06; Vol. 367 (6482), pp. 1151-1156.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: RNA Stability*
Transcription, Genetic*
RNA, Messenger/*metabolism
Sequence Analysis, RNA/*methods
Single-Cell Analysis/*methods
Animals ; Humans ; Indicators and Reagents/chemistry ; K562 Cells ; Mice ; Uridine/analogs & derivatives

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Skocz do pozycji: 14.

Tytuł:: Persistent features of intermittent transcription.
Autorzy:: Wilkinson M; Chan Zuckerberg Biohub, 499 Illinois Street, San Francisco, CA, 94158, USA. .; School of Mathematics and Statistics, The Open University, Walton Hall, Milton Keynes, MK7 6AA, UK. .
Darmanis S; Chan Zuckerberg Biohub, 499 Illinois Street, San Francisco, CA, 94158, USA.
Pisco AO; Chan Zuckerberg Biohub, 499 Illinois Street, San Francisco, CA, 94158, USA.
Huber G; Chan Zuckerberg Biohub, 499 Illinois Street, San Francisco, CA, 94158, USA.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2020 Feb 21; Vol. 10 (1), pp. 3138. Date of Electronic Publication: 2020 Feb 21.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Transcription, Genetic*
DNA/*genetics
RNA, Messenger/*genetics
Animals ; Cell Separation ; DNA/metabolism ; Databases, Factual ; Flow Cytometry ; Liver/metabolism ; Mice ; Models, Statistical ; Myocardium/metabolism ; Probability ; RNA, Messenger/metabolism ; Single-Cell Analysis ; Stochastic Processes ; Systems Biology ; Time Factors ; Transcriptional Activation

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Skocz do pozycji: 15.

Tytuł:: Trans-splicing of mRNAs links gene transcription to translational control regulated by mTOR.
Autorzy:: Danks GB; Sars International Centre for Marine Molecular Biology, University of Bergen, Bergen, Norway. .
Galbiati H; Sars International Centre for Marine Molecular Biology, University of Bergen, Bergen, Norway.
Raasholm M; Sars International Centre for Marine Molecular Biology, University of Bergen, Bergen, Norway.; University of Ulm, Ulm, Germany.
Torres Cleuren YN; Sars International Centre for Marine Molecular Biology, University of Bergen, Bergen, Norway.; Computational Biology Unit, Department of Informatics, University of Bergen, Bergen, Norway.
Valen E; Sars International Centre for Marine Molecular Biology, University of Bergen, Bergen, Norway.; Computational Biology Unit, Department of Informatics, University of Bergen, Bergen, Norway.
Navratilova P; Sars International Centre for Marine Molecular Biology, University of Bergen, Bergen, Norway.; Inst Expt Bot, Czech Acad Sci, Centre of the Region Hana for Biotechnological and Agricultural Research, Olomouc, Czech Republic.
Thompson EM; Sars International Centre for Marine Molecular Biology, University of Bergen, Bergen, Norway. .; Department of Biological Sciences, University of Bergen, Bergen, Norway. .; Pokaż więcej
Źródło:: BMC genomics [BMC Genomics] 2019 Nov 29; Vol. 20 (1), pp. 908. Date of Electronic Publication: 2019 Nov 29.
Typ publikacji:: Journal Article
MeSH Terms:: Gene Expression Regulation*
Protein Biosynthesis*
Trans-Splicing*
Transcription, Genetic*
RNA, Messenger/*metabolism
TOR Serine-Threonine Kinases/*metabolism
Animals ; Caenorhabditis elegans/genetics ; Caenorhabditis elegans/growth & development ; Female ; Mammals/genetics ; Nucleotide Motifs ; Oocytes/metabolism ; RNA, Messenger/chemistry ; TOR Serine-Threonine Kinases/antagonists & inhibitors ; Urochordata/genetics

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Skocz do pozycji: 16.

Tytuł:: Feedback to the central dogma: cytoplasmic mRNA decay and transcription are interdependent processes.
Autorzy:: Hartenian E; Department of Molecular & Cell Biology, University of California, Berkeley, CA, USA.
Glaunsinger BA; Department of Molecular & Cell Biology, University of California, Berkeley, CA, USA.; Department of Plant & Microbial Biology, University of California, Berkeley, CA, USA.; Howard Hughes Medical Institute, Berkeley, CA, USA.; Pokaż więcej
Źródło:: Critical reviews in biochemistry and molecular biology [Crit Rev Biochem Mol Biol] 2019 Aug; Vol. 54 (4), pp. 385-398. Date of Electronic Publication: 2019 Oct 27.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Review
MeSH Terms:: Transcription, Genetic*
Cytoplasm/*genetics
RNA Stability/*genetics
RNA, Messenger/*genetics
Animals ; Cell Nucleus/genetics ; Cell Nucleus/metabolism ; Codon, Terminator/genetics ; Cytoplasm/metabolism ; Exoribonucleases/metabolism ; Gene Expression ; Homeostasis/genetics ; Humans ; Infections/genetics ; Microtubule-Associated Proteins/metabolism ; RNA Polymerase II/genetics ; RNA Polymerase II/metabolism ; RNA, Messenger/metabolism ; RNA-Binding Proteins/genetics

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Skocz do pozycji: 17.

Tytuł:: Multifaceted regulation of translation by the epitranscriptomic modification N -methyladenosine.
Autorzy:: Liu XM; School of Life Science and Technology, China Pharmaceutical University, Nanjing, China.
Zhou J; School of Life Science and Technology, China Pharmaceutical University, Nanjing, China.; State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China.; Pokaż więcej
Źródło:: Critical reviews in biochemistry and molecular biology [Crit Rev Biochem Mol Biol] 2021 Apr; Vol. 56 (2), pp. 137-148. Date of Electronic Publication: 2021 Jan 08.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:: Epigenesis, Genetic*
Protein Biosynthesis*
Adenosine/*analogs & derivatives
RNA, Messenger/*genetics
Adenosine/genetics ; Animals ; Humans ; Transcription, Genetic ; Transcriptome

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Skocz do pozycji: 18.

Tytuł:: Mechanism and consequences of herpes simplex virus 1-mediated regulation of host mRNA alternative polyadenylation.
Autorzy:: Wang X; Department of Microbiology and Molecular Genetics, School of Medicine, University of California, Irvine, California, United States America.
Liu L; Department of Microbiology and Molecular Genetics, School of Medicine, University of California, Irvine, California, United States America.
Whisnant AW; Institute for Virology and Immunobiology, Julius-Maximilians-University Würzburg, Germany.
Hennig T; Institute for Virology and Immunobiology, Julius-Maximilians-University Würzburg, Germany.
Djakovic L; Institute for Virology and Immunobiology, Julius-Maximilians-University Würzburg, Germany.
Haque N; Department of Microbiology and Molecular Genetics, School of Medicine, University of California, Irvine, California, United States America.
Bach C; Department of Microbiology and Molecular Genetics, School of Medicine, University of California, Irvine, California, United States America.
Sandri-Goldin RM; Department of Microbiology and Molecular Genetics, School of Medicine, University of California, Irvine, California, United States America.
Erhard F; Institute for Virology and Immunobiology, Julius-Maximilians-University Würzburg, Germany.
Friedel CC; Institute of Informatics, Ludwig-Maximilians-Universität München, Germany.
Dölken L; Institute for Virology and Immunobiology, Julius-Maximilians-University Würzburg, Germany.; Helmholtz Institute for RNA-based Infection Research, Würzburg, Germany.
Shi Y; Department of Microbiology and Molecular Genetics, School of Medicine, University of California, Irvine, California, United States America.; Pokaż więcej
Źródło:: PLoS genetics [PLoS Genet] 2021 Mar 08; Vol. 17 (3), pp. e1009263. Date of Electronic Publication: 2021 Mar 08 (Print Publication: 2021).
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Gene Expression Regulation*
Herpes Simplex/*genetics
Herpes Simplex/*virology
Herpesvirus 1, Human/*physiology
Host-Pathogen Interactions/*genetics
RNA, Messenger/*genetics
Gene Expression Profiling ; Humans ; Models, Biological ; Polyadenylation ; RNA Isoforms ; RNA Transport ; Transcription, Genetic ; Transcriptome

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Skocz do pozycji: 19.

Tytuł:: Structure of a transcribing RNA polymerase II-U1 snRNP complex.
Autorzy:: Zhang S; Department of Molecular Biology, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, 37077 Göttingen, Germany.
Aibara S; Department of Molecular Biology, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, 37077 Göttingen, Germany.
Vos SM; Department of Molecular Biology, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, 37077 Göttingen, Germany.
Agafonov DE; Cellular Biochemistry, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, 37077 Göttingen, Germany.
Lührmann R; Cellular Biochemistry, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, 37077 Göttingen, Germany.
Cramer P; Department of Molecular Biology, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, 37077 Göttingen, Germany. .; Pokaż więcej
Źródło:: Science (New York, N.Y.) [Science] 2021 Jan 15; Vol. 371 (6526), pp. 305-309.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Alternative Splicing*
RNA Polymerase II/*chemistry
RNA, Messenger/*biosynthesis
Ribonucleoprotein, U1 Small Nuclear/*chemistry
Spliceosomes/*chemistry
Animals ; Cryoelectron Microscopy ; Humans ; Introns ; Nucleic Acid Conformation ; Protein Binding ; Protein Domains ; RNA Precursors/chemistry ; RNA, Messenger/chemistry ; Spliceosomes/metabolism ; Sus scrofa ; Transcription, Genetic

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Skocz do pozycji: 20.

Tytuł:: Safe and effective aerosolization of in vitro transcribed mRNA to the respiratory tract epithelium of horses without a transfection agent.
Autorzy:: Legere RM; Department of Large Animal Clinical Sciences, College of Veterinary Medicine, Texas A&M University, College Station, TX, USA.
Cohen ND; Department of Large Animal Clinical Sciences, College of Veterinary Medicine, Texas A&M University, College Station, TX, USA. .
Poveda C; Department of Pediatrics, National School of Tropical Medicine, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.
Bray JM; Department of Large Animal Clinical Sciences, College of Veterinary Medicine, Texas A&M University, College Station, TX, USA.
Barhoumi R; Department of Veterinary Integrative Biosciences, College of Veterinary Medicine, Texas A&M University, College Station, TX, USA.
Szule JA; Department of Veterinary Pathobiology, College of Veterinary Medicine, Texas A&M University, College Station, TX, USA.
de la Concha-Bermejillo A; Texas A&M Veterinary Medical Diagnostic Laboratory, Texas A&M University, College Station, TX, USA.
Bordin AI; Department of Large Animal Clinical Sciences, College of Veterinary Medicine, Texas A&M University, College Station, TX, USA.
Pollet J; Department of Pediatrics, National School of Tropical Medicine, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA. .; Texas Children's Hospital Center for Vaccine Development, Baylor College of Medicine, 1102 Bates Street, Houston, TX, USA. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2021 Jan 11; Vol. 11 (1), pp. 371. Date of Electronic Publication: 2021 Jan 11.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Horses*
Nasal Sprays*
Respiratory Mucosa*/drug effects
Respiratory Mucosa*/metabolism
RNA, Messenger/*administration & dosage
Animals ; Animals, Newborn ; Cells, Cultured ; Drug Carriers/administration & dosage ; Drug Carriers/adverse effects ; Drug Carriers/pharmacokinetics ; Drug Delivery Systems/adverse effects ; Drug Delivery Systems/methods ; Drug Delivery Systems/veterinary ; Epithelial Cells/drug effects ; Epithelial Cells/metabolism ; Female ; Lung/drug effects ; Lung/metabolism ; Nebulizers and Vaporizers/veterinary ; Polyethyleneimine/administration & dosage ; Polyethyleneimine/chemistry ; RNA, Messenger/adverse effects ; RNA, Messenger/pharmacokinetics ; Transcription, Genetic ; Transfection/methods ; Transfection/veterinary ; Vaccines, DNA/administration & dosage ; Vaccines, DNA/adverse effects ; Vaccines, DNA/pharmacokinetics

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Skocz do pozycji: 21.

Tytuł:: The nonlinear dynamics and fluctuations of mRNA levels in cell cycle coupled transcription.
Autorzy:: Sun Q; Center for Applied Mathematics, Guangzhou University, Guangzhou, 510006, China.; Department of Mathematics, Michigan State University, East Lansing, Michigan, United States of America.
Jiao F; Center for Applied Mathematics, Guangzhou University, Guangzhou, 510006, China.; Department of Mathematics, Michigan State University, East Lansing, Michigan, United States of America.
Lin G; Center for Applied Mathematics, Guangzhou University, Guangzhou, 510006, China.; Department of Mathematics, Michigan State University, East Lansing, Michigan, United States of America.
Yu J; Center for Applied Mathematics, Guangzhou University, Guangzhou, 510006, China.
Tang M; Department of Mathematics, Michigan State University, East Lansing, Michigan, United States of America.; Pokaż więcej
Źródło:: PLoS computational biology [PLoS Comput Biol] 2019 Apr 29; Vol. 15 (4), pp. e1007017. Date of Electronic Publication: 2019 Apr 29 (Print Publication: 2019).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Cell Cycle*/genetics
Cell Cycle*/physiology
Models, Biological*
RNA, Messenger*/genetics
RNA, Messenger*/metabolism
Transcription, Genetic*/genetics
Transcription, Genetic*/physiology
Animals ; Cell Line ; Computational Biology ; Mice ; Nonlinear Dynamics

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Skocz do pozycji: 22.

Tytuł:: Transcriptional Regulation: Molecules, Involved Mechanisms, and Misregulation.
Autorzy:: Casamassimi A; Department of Precision Medicine, University of Campania 'Luigi Vanvitelli', Via L. De Crecchio, 80138 Naples, Italy. .
Ciccodicola A; Institute of Genetics and Biophysics 'Adriano Buzzati Traverso', CNR, 80131 Naples, Italy. .; Department of Science and Technology, University of Naples 'Parthenope', 80143 Naples, Italy. .; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2019 Mar 14; Vol. 20 (6). Date of Electronic Publication: 2019 Mar 14.
Typ publikacji:: Editorial; Introductory Journal Article
MeSH Terms:: Transcription, Genetic*
RNA, Messenger/*metabolism
Animals ; DNA Methylation ; Gene Expression Regulation ; Humans ; RNA Caps/metabolism ; RNA Splicing ; RNA, Messenger/chemistry

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Skocz do pozycji: 23.

Tytuł:: Synthesis and Translation of Viral mRNA in Reovirus-Infected Cells: Progress and Remaining Questions.
Autorzy:: Lemay G; Département de microbiologie, infectiologie et immunologie, Université de Montréal, Montréal, QC H3C 3J7, Canada. .; Pokaż więcej
Źródło:: Viruses [Viruses] 2018 Nov 27; Vol. 10 (12). Date of Electronic Publication: 2018 Nov 27.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:: Gene Expression Regulation, Viral*
Protein Biosynthesis*
RNA, Viral*
Transcription, Genetic*
RNA, Messenger/*genetics
Reoviridae/*physiology
Reoviridae Infections/*virology
Animals ; Host-Pathogen Interactions/genetics ; Humans ; Reoviridae/ultrastructure ; Virion ; Virus Replication

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Skocz do pozycji: 24.

Tytuł:: Insight into Influenza: A Virus Cap-Snatching.
Autorzy:: De Vlugt C; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada. .
Sikora D; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada. .
Pelchat M; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada. .; Pokaż więcej
Źródło:: Viruses [Viruses] 2018 Nov 16; Vol. 10 (11). Date of Electronic Publication: 2018 Nov 16.
Typ publikacji:: Journal Article; Review
MeSH Terms:: RNA Caps*
Transcription, Genetic*
Influenza A virus/*physiology
RNA Polymerase II/*metabolism
RNA, Messenger/*metabolism
RNA, Viral/*metabolism
RNA-Binding Proteins/*metabolism
Viral Core Proteins/*metabolism
Nucleocapsid Proteins ; Protein Binding ; Virus Replication

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Skocz do pozycji: 25.

Tytuł:: Transcriptional analysis of viral mRNAs reveals common transcription patterns in cells infected by five different filoviruses.
Autorzy:: Albariño CG; Viral Special Pathogens Branch, Centers for Disease Control and Prevention, Atlanta, GA, United States of America.
Wiggleton Guerrero L; Viral Special Pathogens Branch, Centers for Disease Control and Prevention, Atlanta, GA, United States of America.
Chakrabarti AK; Viral Special Pathogens Branch, Centers for Disease Control and Prevention, Atlanta, GA, United States of America.
Nichol ST; Viral Special Pathogens Branch, Centers for Disease Control and Prevention, Atlanta, GA, United States of America.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2018 Aug 02; Vol. 13 (8), pp. e0201827. Date of Electronic Publication: 2018 Aug 02 (Print Publication: 2018).
Typ publikacji:: Journal Article; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:: Transcription, Genetic*
Filoviridae/*metabolism
Filoviridae Infections/*metabolism
RNA, Messenger/*metabolism
RNA, Viral/*metabolism
Animals ; Cell Culture Techniques ; Cells, Cultured ; Chlorocebus aethiops ; Cricetinae ; Humans ; Liver/metabolism ; Liver/virology ; Macrophages/metabolism ; Macrophages/virology ; Temperature

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