Temat: "Transcription Factor HES-1" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Loss of HES1 expression is associated with extracellular matrix remodeling and tumor immune suppression in KRAS mutant colon adenocarcinomas.
Autorzy:: Wang L; Department of Pathology, Case Western Reserve University, Cleveland, OH, USA.; Department of Pathology, Fudan University Shanghai Cancer Center, Shanghai, China.
Gu W; Department of Diagnostic and Interventional Radiology, University of Tsukuba, Tsukuba, Ibaraki, Japan.
Zou B; Department of Pathology and Genomic Medicine, Houston Methodist Research Institute, Houston, TX, USA.
Kalady M; Department of Colorectal Surgery, Cleveland Clinic, Cleveland, OH, USA.; Division of Colon and Rectal Surgery, Ohio State University Wexner Medical Center and James Comprehensive Cancer Center, Columbus, OH, USA.
Xin W; Department of Pathology, University Hospitals Cleveland Medical Center, Cleveland, OH, USA.; Department of Pathology, University of South Alabama Hospital, Mobile, AL, USA.
Zhou L; Department of Pathology, Case Western Reserve University, Cleveland, OH, USA. .; Department of Pathology, University Hospitals Cleveland Medical Center, Cleveland, OH, USA. .; Department of Pathology and Genomic Medicine, Houston Methodist Research Institute, Houston, TX, USA. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2023 Sep 25; Vol. 13 (1), pp. 15999. Date of Electronic Publication: 2023 Sep 25.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Colonic Neoplasms*/genetics
Adenocarcinoma*/genetics
Humans ; Proto-Oncogene Proteins p21(ras)/genetics ; Immunosuppression Therapy ; Extracellular Matrix/genetics ; Tumor Microenvironment/genetics ; Transcription Factor HES-1/genetics

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 2.

Tytuł:: HES and Mox genes are expressed during early mesoderm formation in a mollusk with putative ancestral features.
Autorzy:: Sachslehner A; Department of Evolutionary Biology, Unit for Integrative Zoology, University of Vienna, Althanstrasse 14, 1090, Vienna, Austria.
Zieger E; Department of Evolutionary Biology, Unit for Integrative Zoology, University of Vienna, Althanstrasse 14, 1090, Vienna, Austria.
Calcino A; Department of Evolutionary Biology, Unit for Integrative Zoology, University of Vienna, Althanstrasse 14, 1090, Vienna, Austria.
Wanninger A; Department of Evolutionary Biology, Unit for Integrative Zoology, University of Vienna, Althanstrasse 14, 1090, Vienna, Austria. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2021 Sep 09; Vol. 11 (1), pp. 18030. Date of Electronic Publication: 2021 Sep 09.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Genetic Pleiotropy*
Homeodomain Proteins/*genetics
Mesoderm/*metabolism
Myosin Heavy Chains/*genetics
Polyplacophora/*genetics
Transcription Factor HES-1/*genetics
Animals ; Annelida/classification ; Annelida/genetics ; Biological Evolution ; Gastrulation/genetics ; Gene Expression Regulation, Developmental ; Homeodomain Proteins/metabolism ; Mesoderm/cytology ; Mesoderm/growth & development ; Morphogenesis/genetics ; Myosin Heavy Chains/metabolism ; Phylogeny ; Polyplacophora/classification ; Polyplacophora/growth & development ; Polyplacophora/metabolism ; Transcription Factor HES-1/metabolism ; Urochordata/classification ; Urochordata/genetics

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 3.

Tytuł:: Sirt3 promotes the autophagy of HK‑2 human proximal tubular epithelial cells via the inhibition of Notch‑1/Hes‑1 signaling.
Autorzy:: Wang Y; Department of Nephrology, Bayan Nur Hospital, Bayan Nur, Inner Mongolia Autonomous Region 015000, P.R. China.
Chang J; Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital of Hainan Medical College, Haikou, Hainan 570102, P.R. China.
Wang ZQ; Department of Nephrology, The Third Hospital of Hebei Medical University, Shijiazhuang, Hebei 050051, P.R. China.
Li Y; Department of Nephrology, The Third Hospital of Hebei Medical University, Shijiazhuang, Hebei 050051, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2021 Sep; Vol. 24 (3). Date of Electronic Publication: 2021 Jul 19.
Typ publikacji:: Journal Article
MeSH Terms:: Autophagy/*drug effects
Epithelial Cells/*metabolism
Receptor, Notch1/*metabolism
Signal Transduction/*drug effects
Sirtuin 3/*metabolism
Sirtuin 3/*pharmacology
Transcription Factor HES-1/*metabolism
Autophagy/genetics ; Autophagy-Related Proteins/genetics ; Autophagy-Related Proteins/metabolism ; Beclin-1/metabolism ; Cell Line ; Cell Survival/drug effects ; Diabetic Nephropathies/metabolism ; Down-Regulation ; Humans ; Receptor, Notch1/genetics ; Sirtuin 3/genetics ; Transcription Factor HES-1/genetics

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 4.

Tytuł:: HES1-mediated down-regulation of miR-138 sustains NOTCH1 activation and promotes proliferation and invasion in renal cell carcinoma.
Autorzy:: Liu S; Department of Urology, The First Hospital of China Medical University, Shenyang, 110001, China.
Dou L; Department of Gynecology, The First Hospital of China Medical University, Shenyang, Liaoning, 110001, China.
Miao M; Department of Urology, The First Hospital of China Medical University, Shenyang, 110001, China.
Man X; Department of Urology, The First Hospital of China Medical University, Shenyang, 110001, China.
Wei B; Department of Urology, The First Hospital of China Medical University, Shenyang, 110001, China.
Jiang Z; Department of Urology, The First Hospital of China Medical University, Shenyang, 110001, China.
Ouyang Y; Department of Urology, The First Hospital of China Medical University, Shenyang, 110001, China.
Ozaki T; Laboratory of DNA Damage Signaling, Chiba Cancer Center Research Institute, Chiba, Japan.
Yu M; Department of Laboratory Animal Science, Key Laboratory of Transgenetic Animal Research. No, China Medical University, 77 Puhe Road, Shenyang North New Area, Shenyang, Liaoning Province, 110122, China.
Zhu Y; Department of Urology, The First Hospital of China Medical University, Shenyang, 110001, China. .; Pokaż więcej
Źródło:: Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2023 Mar 28; Vol. 42 (1), pp. 72. Date of Electronic Publication: 2023 Mar 28.
Typ publikacji:: Journal Article
MeSH Terms:: Carcinoma, Renal Cell*/genetics
Carcinoma, Renal Cell*/metabolism
Kidney Neoplasms*/genetics
Kidney Neoplasms*/metabolism
MicroRNAs*/genetics
MicroRNAs*/metabolism
Animals ; Humans ; Mice ; Cell Line, Tumor ; Cell Proliferation ; Down-Regulation ; Gene Expression Regulation, Neoplastic ; Receptor, Notch1/genetics ; Receptor, Notch1/metabolism ; Transcription Factor HES-1/genetics ; Transcription Factor HES-1/metabolism

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 5.

Tytuł:: Visualizing Cell Cycle Phase Organization and Control During Neural Lineage Elaboration.
Autorzy:: Urun FR; Laboratory for Neurodiversity, RIKEN Center for Brain Science, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan.; Graduate School of Science and Engineering, Saitama University, Sakura-ku, Saitama 338-8570, Japan.
Moore AW; Laboratory for Neurodiversity, RIKEN Center for Brain Science, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan.; Pokaż więcej
Źródło:: Cells [Cells] 2020 Sep 17; Vol. 9 (9). Date of Electronic Publication: 2020 Sep 17.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Gene Expression Regulation, Developmental*
Cyclin-Dependent Kinase Inhibitor p27/*genetics
Neural Stem Cells/*metabolism
Olfactory Mucosa/*metabolism
Olfactory Receptor Neurons/*metabolism
Transcription Factor HES-1/*genetics
Animals ; Bacterial Proteins/genetics ; Bacterial Proteins/metabolism ; Cell Cycle/genetics ; Cell Differentiation ; Cell Lineage/genetics ; Cell Tracking/methods ; Cyclin-Dependent Kinase Inhibitor p27/metabolism ; Embryo, Mammalian ; Genes, Reporter ; Humans ; Luminescent Proteins/genetics ; Luminescent Proteins/metabolism ; Mice ; Mice, Transgenic ; Neural Stem Cells/cytology ; Olfactory Mucosa/cytology ; Olfactory Mucosa/growth & development ; Olfactory Receptor Neurons/cytology ; Staining and Labeling/methods ; Transcription Factor HES-1/metabolism ; Red Fluorescent Protein

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 6.

Tytuł:: Patchouli alcohol protects against myocardial ischaemia-reperfusion injury by regulating the Notch1/Hes1 pathway.
Autorzy:: Lu Y; Electrocardiogram room of Department of Functional Examination, Tongde Hospital of Zhejiang Province, Hangzhou, China.
Li SY; College of Pharmacy, Hangzhou Medical College, Hangzhou, China.
Lou H; Electrocardiogram room of Department of Functional Examination, Tongde Hospital of Zhejiang Province, Hangzhou, China.; Pokaż więcej
Źródło:: Pharmaceutical biology [Pharm Biol] 2022 Dec; Vol. 60 (1), pp. 949-957.
Typ publikacji:: Journal Article; Randomized Controlled Trial, Veterinary
MeSH Terms:: Myocardial Ischemia*/metabolism
Myocardial Reperfusion Injury*/drug therapy
Animals ; Apoptosis ; Caspase 3/metabolism ; Cell Line ; Male ; Mice ; Mice, Inbred C57BL ; Myocytes, Cardiac ; Rats ; Receptor, Notch1 ; Sesquiterpenes ; Stroke Volume ; Transcription Factor HES-1/metabolism ; Ventricular Function, Left

Czasopismo naukowe

na półce

Pełny tekst Szczegóły

Skocz do pozycji: 7.

Tytuł:: Peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α) overexpression alleviates endoplasmic reticulum stress after acute kidney injury.
Autorzy:: Pan H; Department of Nephrology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P. R. China.
Hu Z; Department of Nephrology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P. R. China.
Shao Z; Department of Nephrology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P. R. China.
Ning Y; Department of Nephrology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P. R. China.; Pokaż więcej
Źródło:: Renal failure [Ren Fail] 2022 Dec; Vol. 44 (1), pp. 358-367.
Typ publikacji:: Journal Article
MeSH Terms:: Acute Kidney Injury*/etiology
Acute Kidney Injury*/metabolism
Endoplasmic Reticulum Stress*
Organelle Biogenesis*
Reperfusion Injury*/complications
Reperfusion Injury*/metabolism
Kidney/*metabolism
Mitochondria/*metabolism
Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha/*metabolism
Animals ; GTP Phosphohydrolases/metabolism ; Gene Expression Profiling/methods ; Mice ; Transcription Factor HES-1/metabolism ; Up-Regulation

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 8.

Tytuł:: Whole-Genome and Transcriptome Sequencing Identified NOTCH2 and HES1 as Potential Markers of Response to Imatinib in Desmoid Tumor (Aggressive Fibromatosis): A Phase II Trial Study.
Autorzy:: Kwon J; Department of Bio and Brain Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Korea.
Lee JH; Department of Bio and Brain Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Korea.
Lee YH; Department of Radiology, Yonsei University College of Medicine, Seoul, Korea.
Lee J; Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Ahn JH; Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Kim SH; Division of Hematology and Medical Oncology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.
Kim SH; Department of Orthopedic Surgery, Yonsei University College of Medicine, Seoul, Korea.
Kim TI; Division of Gastroenterology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
Yun KH; Brain Korea 21 PLUS Project for Medical Science, Yonsei University College of Medicine, Seoul, Korea.
Park YS; Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Kim JE; Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Lee KS; Department of Pathology, Seoul National University Bundang Hospital, Seongnam, Korea.
Choi JK; Department of Bio and Brain Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Korea.
Kim HS; Brain Korea 21 PLUS Project for Medical Science, Yonsei University College of Medicine, Seoul, Korea.; Division of Medical Oncology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.; Pokaż więcej
Źródło:: Cancer research and treatment [Cancer Res Treat] 2022 Oct; Vol. 54 (4), pp. 1240-1255. Date of Electronic Publication: 2022 Jan 17.
Typ publikacji:: Clinical Trial, Phase II; Journal Article
MeSH Terms:: Fibromatosis, Aggressive*/drug therapy
Fibromatosis, Aggressive*/genetics
Fibromatosis, Aggressive*/pathology
Humans ; Imatinib Mesylate/pharmacology ; Imatinib Mesylate/therapeutic use ; Mutation ; Prospective Studies ; RNA ; Receptor, Notch2/genetics ; Retrospective Studies ; Transcription Factor HES-1/genetics ; Transcription Factor HES-1/metabolism ; Transcriptome ; beta Catenin/metabolism

Czasopismo naukowe

na półce

Pełny tekst Szczegóły

Skocz do pozycji: 9.

Tytuł:: Ticagrelor Increases SIRT1 and HES1 mRNA Levels in Peripheral Blood Cells from Patients with Stable Coronary Artery Disease and Chronic Obstructive Pulmonary Disease.
Autorzy:: Aquila G; Department of Medical Sciences, University of Ferrara, 44121 Ferrara, Italy.
Vieceli Dalla Sega F; Maria Cecilia Hospital, GVM Care & Research, 48033 Cotignola, Italy.
Marracino L; Department of Morphology, Surgery and Experimental Medicine and Laboratory for Technologies of Advanced Therapies (LTTA), University of Ferrara, 44121 Ferrara, Italy.
Pavasini R; Cardiovascular Institute, Azienda Ospedaliero-Universitaria di Ferrara, 44124 Cona, Italy.
Cardelli LS; Cardiovascular Institute, Azienda Ospedaliero-Universitaria di Ferrara, 44124 Cona, Italy.
Piredda A; Cardiovascular Institute, Azienda Ospedaliero-Universitaria di Ferrara, 44124 Cona, Italy.
Scoccia A; Cardiovascular Institute, Azienda Ospedaliero-Universitaria di Ferrara, 44124 Cona, Italy.
Martino V; Department of Medical Sciences, University of Ferrara, 44121 Ferrara, Italy.
Fortini F; Maria Cecilia Hospital, GVM Care & Research, 48033 Cotignola, Italy.
Bononi I; Department of Morphology, Surgery and Experimental Medicine and Laboratory for Technologies of Advanced Therapies (LTTA), University of Ferrara, 44121 Ferrara, Italy.
Martini F; Department of Morphology, Surgery and Experimental Medicine and Laboratory for Technologies of Advanced Therapies (LTTA), University of Ferrara, 44121 Ferrara, Italy.
Manfrini M; Maria Cecilia Hospital, GVM Care & Research, 48033 Cotignola, Italy.
Pannuti A; University of Hawaii Cancer Center, University of Hawaii, Honolulu, HI 96813, USA.
Ferrari R; Maria Cecilia Hospital, GVM Care & Research, 48033 Cotignola, Italy.; Cardiovascular Institute, Azienda Ospedaliero-Universitaria di Ferrara, 44124 Cona, Italy.
Rizzo P; Maria Cecilia Hospital, GVM Care & Research, 48033 Cotignola, Italy.; Department of Morphology, Surgery and Experimental Medicine and Laboratory for Technologies of Advanced Therapies (LTTA), University of Ferrara, 44121 Ferrara, Italy.
Campo G; Maria Cecilia Hospital, GVM Care & Research, 48033 Cotignola, Italy.; Cardiovascular Institute, Azienda Ospedaliero-Universitaria di Ferrara, 44124 Cona, Italy.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2020 Feb 25; Vol. 21 (5). Date of Electronic Publication: 2020 Feb 25.
Typ publikacji:: Clinical Trial; Journal Article
MeSH Terms:: Blood Cells/*drug effects
Coronary Artery Disease/*metabolism
Platelet Aggregation Inhibitors/*pharmacology
Pulmonary Disease, Chronic Obstructive/*metabolism
Sirtuin 1/*genetics
Ticagrelor/*pharmacology
Transcription Factor HES-1/*genetics
Blood Cells/metabolism ; Cells, Cultured ; Epidermal Growth Factor/genetics ; Epidermal Growth Factor/metabolism ; Human Umbilical Vein Endothelial Cells/drug effects ; Human Umbilical Vein Endothelial Cells/metabolism ; Humans ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Receptors, Notch/genetics ; Receptors, Notch/metabolism ; Signal Transduction ; Sirtuin 1/metabolism ; Transcription Factor HES-1/metabolism

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 10.

Tytuł:: Uniform and Robust Nuclear Expression of HES1 in Neuroendocrine Neoplasms.
Autorzy:: Cui M; University Hospitals Cleveland Medical Center, Cleveland, OH, USA.; Case Western Reserve University, Cleveland, OH, USA.
Cai Z; University Hospitals Cleveland Medical Center, Cleveland, OH, USA.; Case Western Reserve University, Cleveland, OH, USA.
Awadallah A; University Hospitals Cleveland Medical Center, Cleveland, OH, USA.
Xin W; University Hospitals Cleveland Medical Center, Cleveland, OH, USA.; Case Western Reserve University, Cleveland, OH, USA.; Pokaż więcej
Źródło:: International journal of surgical pathology [Int J Surg Pathol] 2019 Dec; Vol. 27 (8), pp. 844-851. Date of Electronic Publication: 2019 Jun 24.
Typ publikacji:: Journal Article
MeSH Terms:: Biomarkers, Tumor/*metabolism
Carcinoid Tumor/*pathology
Carcinoma, Neuroendocrine/*pathology
Transcription Factor HES-1/*metabolism
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Biomarkers, Tumor/analysis ; Cell Nucleus/pathology ; Female ; Gastrointestinal Tract/cytology ; Gastrointestinal Tract/pathology ; Humans ; Immunohistochemistry ; Lung/cytology ; Lung/pathology ; Male ; Middle Aged ; Pancreas/cytology ; Pancreas/pathology ; Transcription Factor HES-1/analysis

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 11.

Tytuł:: Sequential combination of cisplatin with eugenol targets ovarian cancer stem cells through the Notch-Hes1 signalling pathway.
Autorzy:: Islam SS; Cancer Biology and Experimental Therapeutics, Department of Molecular Oncology, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.
Aboussekhra A; Cancer Biology and Experimental Therapeutics, Department of Molecular Oncology, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia. .; Pokaż więcej
Źródło:: Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2019 Aug 30; Vol. 38 (1), pp. 382. Date of Electronic Publication: 2019 Aug 30.
Typ publikacji:: Journal Article
MeSH Terms:: Anti-Infective Agents/*therapeutic use
Antineoplastic Agents/*therapeutic use
Cisplatin/*therapeutic use
Eugenol/*therapeutic use
Ovarian Neoplasms/*drug therapy
Ovarian Neoplasms/*genetics
Receptor, Notch1/*genetics
Transcription Factor HES-1/*genetics
Animals ; Anti-Infective Agents/pharmacology ; Antineoplastic Agents/pharmacology ; Cell Line, Tumor ; Cisplatin/pharmacology ; Eugenol/pharmacology ; Female ; Humans ; Mice ; Ovarian Neoplasms/pathology ; Receptor, Notch1/metabolism ; Signal Transduction ; Transcription Factor HES-1/metabolism

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 12.

Tytuł:: Transcription Repressor Hes1 Contributes to Neuropathic Pain Development by Modifying CDK9/RNAPII-Dependent Spinal mGluR5 Transcription.
Autorzy:: Hsieh MC; Department of Medicine, Mackay Medical College, New Taipei 25244, Taiwan.
Peng HY; Department of Medicine, Mackay Medical College, New Taipei 25244, Taiwan.
Ho YC; Department of Medicine, Mackay Medical College, New Taipei 25244, Taiwan.
Lai CY; Department of Medicine, Mackay Medical College, New Taipei 25244, Taiwan.
Cheng JK; Department of Medicine, Mackay Medical College, New Taipei 25244, Taiwan.; Department of Anesthesiology, Mackay Memorial Hospital, Taipei 10449, Taiwan.
Chen GD; Department of Obstetrics and Gynecology, Chung-Shan Medical University Hospital, Chung-Shan Medical University, Taichung 40201, Taiwan.
Lin TB; Department of Physiology, School of Medicine, College of Medicine, Taipei Medical University, Taipei 11031, Taiwan. .; Graduate Institute of Basic Medical Science, China Medical University, Taichung 40402, Taiwan. .; Department of Biotechnology, College of Medical and Health Science, Asia University, Taichung 41354, Taiwan. .; Cell Physiology and Molecular Image Research Center, Wan Fang Hospital, Taipei Medical University, Taipei 11689, Taiwan. .; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2019 Aug 26; Vol. 20 (17). Date of Electronic Publication: 2019 Aug 26.
Typ publikacji:: Journal Article
MeSH Terms:: Cyclin-Dependent Kinase 9/*metabolism
Neuralgia/*etiology
Neuralgia/*metabolism
RNA Polymerase II/*metabolism
Receptor, Metabotropic Glutamate 5/*genetics
Spinal Cord/*metabolism
Transcription Factor HES-1/*genetics
Animals ; Behavior, Animal ; Disease Models, Animal ; Gene Expression ; Gene Expression Regulation ; Gene Knockdown Techniques ; Hyperalgesia/etiology ; Hyperalgesia/metabolism ; Male ; Phenotype ; Promoter Regions, Genetic ; Protein Binding ; Rats ; Spinal Cord/physiopathology ; Transcription Factor HES-1/metabolism ; Transcription Factors/metabolism ; Transcription, Genetic

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 13.

Tytuł:: Exposure to PM 2.5 affects blood lipid levels in asthmatic rats through notch signaling pathway.
Autorzy:: Zhang T; Department of Occupational and Environmental Health, School of Public Health, Jilin University, 1163 Xin Min Street, Changchun, 130021, China.
Zheng Y; The Department of Cadre ward, the first Hospital of Jilin University, Changchun, Jilin, 130021, China.
Gao Y; Department of Occupational and Environmental Health, School of Public Health, Jilin University, 1163 Xin Min Street, Changchun, 130021, China.
Zhao T; Department of Occupational and Environmental Health, School of Public Health, Jilin University, 1163 Xin Min Street, Changchun, 130021, China.
Guo S; Department of Occupational and Environmental Health, School of Public Health, Jilin University, 1163 Xin Min Street, Changchun, 130021, China.
Yang L; Department of Occupational and Environmental Health, School of Public Health, Jilin University, 1163 Xin Min Street, Changchun, 130021, China.
Shi Y; Department of Occupational and Environmental Health, School of Public Health, Jilin University, 1163 Xin Min Street, Changchun, 130021, China.
Zhou L; Department of Occupational and Environmental Health, School of Public Health, Jilin University, 1163 Xin Min Street, Changchun, 130021, China. .
Ye L; Department of Occupational and Environmental Health, School of Public Health, Jilin University, 1163 Xin Min Street, Changchun, 130021, China. .; Pokaż więcej
Źródło:: Lipids in health and disease [Lipids Health Dis] 2019 Aug 07; Vol. 18 (1), pp. 160. Date of Electronic Publication: 2019 Aug 07.
Typ publikacji:: Journal Article
MeSH Terms:: Asthma/*blood
Dyslipidemias/*blood
Gene Expression/*drug effects
Particulate Matter/*administration & dosage
Signal Transduction/*drug effects
Transcription Factor HES-1/*genetics
Animals ; Asthma/chemically induced ; Asthma/genetics ; Cholesterol, HDL/blood ; Cholesterol, LDL/blood ; Diamines/pharmacology ; Disease Models, Animal ; Dyslipidemias/chemically induced ; Dyslipidemias/genetics ; Female ; Lipid Metabolism/drug effects ; Male ; Ovalbumin ; Particulate Matter/antagonists & inhibitors ; Rats ; Rats, Wistar ; Thiazoles/pharmacology ; Transcription Factor HES-1/metabolism ; Triglycerides/blood

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 14.

Tytuł:: Dysregulation of SIRT3 SUMOylation Confers AML Chemoresistance via Controlling HES1-Dependent Fatty Acid Oxidation.
Autorzy:: Zhang Y; Department of Biochemistry and Molecular Cell Biology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
Shen Y; Department of Biochemistry and Molecular Cell Biology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.; Department of Biological Science, School of Life Science, Shaanxi Normal University, Xi'an 710119, China.
Wei W; Department of Biochemistry and Molecular Cell Biology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
Wang W; Department of Biochemistry and Molecular Cell Biology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
Jiang D; Department of Biochemistry and Molecular Cell Biology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
Ren Y; Department of Biochemistry and Molecular Cell Biology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
Peng Z; Department of Biochemistry and Molecular Cell Biology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
Fan Q; Department of Biochemistry and Molecular Cell Biology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
Cheng J; Department of Biochemistry and Molecular Cell Biology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
Ma J; Department of Biochemistry and Molecular Cell Biology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2022 Jul 27; Vol. 23 (15). Date of Electronic Publication: 2022 Jul 27.
Typ publikacji:: Journal Article
MeSH Terms:: Leukemia, Myeloid, Acute*/drug therapy
Leukemia, Myeloid, Acute*/genetics
Leukemia, Myeloid, Acute*/metabolism
Sirtuin 3*/genetics
Sirtuin 3*/metabolism
Animals ; Drug Resistance, Neoplasm/genetics ; Fatty Acids/metabolism ; Humans ; Mice ; Sumoylation ; Transcription Factor HES-1/genetics ; Transcription Factor HES-1/metabolism

Czasopismo naukowe

na półce

Pełny tekst Szczegóły

Skocz do pozycji: 15.

Tytuł:: Notch1/Hes1‑PTEN/AKT/IL‑17A feedback loop regulates Th17 cell differentiation in mouse psoriasis‑like skin inflammation.
Autorzy:: Lin YW; Department of Dermatology, Binzhou Medical University Hospital, Binzhou, Shandong 256603, P.R. China.
Li XX; Department of Dermatology, Binzhou Medical University Hospital, Binzhou, Shandong 256603, P.R. China.
Fu FH; Department of Dermatology, Binzhou Medical University Hospital, Binzhou, Shandong 256603, P.R. China.
Liu B; Institute for Metabolic and Neuropsychiatric Disorders, Binzhou Medical University Hospital, Binzhou, Shandong 256603, P.R. China.
Xing X; Department of Dermatology, Binzhou Medical University Hospital, Binzhou, Shandong 256603, P.R. China.
Qi R; Department of Dermatology, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning 110001, P.R. China.
Ma L; Department of Dermatology, Binzhou Medical University Hospital, Binzhou, Shandong 256603, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2022 Jul; Vol. 26 (1). Date of Electronic Publication: 2022 May 18.
Typ publikacji:: Journal Article
MeSH Terms:: Dermatitis*/metabolism
Lymphadenopathy*/metabolism
Lymphadenopathy*/pathology
Psoriasis*/chemically induced
Psoriasis*/drug therapy
Psoriasis*/genetics
Animals ; Cell Differentiation ; Feedback ; Imiquimod/adverse effects ; Inflammation/pathology ; Interleukin-17/metabolism ; Mechanistic Target of Rapamycin Complex 1/metabolism ; Mice ; Phosphatidylinositol 3-Kinases/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Skin/pathology ; Splenomegaly/metabolism ; Splenomegaly/pathology ; Th17 Cells/metabolism ; Transcription Factor HES-1

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 16.

Tytuł:: Extracellular Vesicles Carrying miR-887-3p Promote Breast Cancer Cell Drug Resistance by Targeting BTBD7 and Activating the Notch1/Hes1 Signaling Pathway.
Autorzy:: Wang B; Department of Medical Laboratory Science, Fuyang Cancer Hospital, Fuyang, Anhui 236000, China.
Wang Y; Department of Medical Laboratory Science, Anhui No. 2 Provincial People's Hospital, Hefei, Anhui 230041, China.; Department of Molecular and Cell Biology, University of Connecticut, Storrs, CT 06269, USA.
Wang X; Department of Medical Laboratory Science, Anhui No. 2 Provincial People's Hospital, Hefei, Anhui 230041, China.
Gu J; Department of Pathology, The Fifth People's Hospital of Wuxi, Nanjing Medical University, Wuxi, Jiangsu 214000, China.
Wu W; Department of Medical Laboratory Science, Anhui No. 2 Provincial People's Hospital, Hefei, Anhui 230041, China.; Department of Oncology, Anhui No. 2 Provincial People's Hospital, Hefei, Anhui 230041, China.
Wu H; Department of Medical Laboratory Science, Anhui No. 2 Provincial People's Hospital, Hefei, Anhui 230041, China.; Department of Oncology, Anhui No. 2 Provincial People's Hospital, Hefei, Anhui 230041, China.
Wang Q; Department of Medical Laboratory Science, Anhui No. 2 Provincial People's Hospital, Hefei, Anhui 230041, China.
Zhou D; Department of Medical Laboratory Science, Anhui No. 2 Provincial People's Hospital, Hefei, Anhui 230041, China.; Department of Oncology, Anhui No. 2 Provincial People's Hospital, Hefei, Anhui 230041, China.; Pokaż więcej
Źródło:: Disease markers [Dis Markers] 2022 May 23; Vol. 2022, pp. 5762686. Date of Electronic Publication: 2022 May 23 (Print Publication: 2022).
Typ publikacji:: Journal Article
MeSH Terms:: Adaptor Proteins, Signal Transducing*/metabolism
Breast Neoplasms*/drug therapy
Breast Neoplasms*/genetics
Breast Neoplasms*/metabolism
Extracellular Vesicles*/genetics
Extracellular Vesicles*/metabolism
MicroRNAs*/genetics
MicroRNAs*/metabolism
Drug Resistance, Neoplasm ; Female ; Humans ; Receptor, Notch1/genetics ; Receptor, Notch1/metabolism ; Signal Transduction ; Transcription Factor HES-1/metabolism

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 17.

Tytuł:: The Notch signaling pathway controls CD8+ T cell differentiation independently of the classical effector HES1.
Autorzy:: De Sousa DM; Maisonneuve-Rosemont Hospital Research Center, Montréal, Québec, Canada.; Département de microbiologie, infectiologie et immunologie, Université de Montréal, Montréal, Québec, Canada.
Duval F; Maisonneuve-Rosemont Hospital Research Center, Montréal, Québec, Canada.; Département de microbiologie, infectiologie et immunologie, Université de Montréal, Montréal, Québec, Canada.
Daudelin JF; Maisonneuve-Rosemont Hospital Research Center, Montréal, Québec, Canada.
Boulet S; Maisonneuve-Rosemont Hospital Research Center, Montréal, Québec, Canada.
Labrecque N; Maisonneuve-Rosemont Hospital Research Center, Montréal, Québec, Canada.; Département de microbiologie, infectiologie et immunologie, Université de Montréal, Montréal, Québec, Canada.; Département de médecine, Université de Montréal, Montréal, Québec, Canada.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2019 Apr 05; Vol. 14 (4), pp. e0215012. Date of Electronic Publication: 2019 Apr 05 (Print Publication: 2019).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: CD8-Positive T-Lymphocytes/*immunology
Cell Differentiation/*immunology
Receptors, Notch/*immunology
Signal Transduction/*immunology
Transcription Factor HES-1/*immunology
Animals ; CD8-Positive T-Lymphocytes/cytology ; Cell Differentiation/genetics ; Mice ; Mice, Knockout ; PTEN Phosphohydrolase/genetics ; PTEN Phosphohydrolase/immunology ; Receptors, Notch/genetics ; Signal Transduction/genetics ; Transcription Factor HES-1/genetics

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 18.

Tytuł:: Activation of Hes1 and Msx1 in Transgenic Mouse Embryonic Stem Cells Increases Differentiation into Neural Crest Derivatives.
Autorzy:: Méndez-Maldonado K; Instituto de Fisiología Celular-Neurociencias, Universidad Nacional Autónoma de México, Ciudad Universitaria, Ciudad de México 04510, México. .; Laboratorio de Reprogramación Celular del Instituto de Fisiología Celular, UNAM en el Instituto Nacional de Neurología y Neurocirugía 'Manuel Velasco Suárez', Ciudad de México 14269, México. .; Posgrado en Ciencias Biológicas, Universidad Nacional Autónoma de México; Ciudad Universitaria, Ciudad de México 04510, México. .
Vega-López G; Instituto Superior de Investigaciones Biológicas (INSIBIO, CONICET-UNT), San Miguel de Tucumán T4000ILI, Argentina. .; Instituto de Biología 'Dr. Francisco D. Barbieri', Facultad de Bioquímica, Química y Farmacia, Universidad Nacional de Tucumán, San Miguel de Tucumán T4000ILI, Argentina. .
Caballero-Chacón S; Facultad de Medicina Veterinaria y Zootecnia, Universidad Nacional Autónoma de México, Ciudad Universitaria, Ciudad de México 04510, México. .
Aybar MJ; Instituto Superior de Investigaciones Biológicas (INSIBIO, CONICET-UNT), San Miguel de Tucumán T4000ILI, Argentina. .; Instituto de Biología 'Dr. Francisco D. Barbieri', Facultad de Bioquímica, Química y Farmacia, Universidad Nacional de Tucumán, San Miguel de Tucumán T4000ILI, Argentina. .
Velasco I; Instituto de Fisiología Celular-Neurociencias, Universidad Nacional Autónoma de México, Ciudad Universitaria, Ciudad de México 04510, México. .; Laboratorio de Reprogramación Celular del Instituto de Fisiología Celular, UNAM en el Instituto Nacional de Neurología y Neurocirugía 'Manuel Velasco Suárez', Ciudad de México 14269, México. .; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2018 Dec 13; Vol. 19 (12). Date of Electronic Publication: 2018 Dec 13.
Typ publikacji:: Journal Article
MeSH Terms:: Chondrocytes/*cytology
MSX1 Transcription Factor/*genetics
Mouse Embryonic Stem Cells/*cytology
Myocytes, Smooth Muscle/*cytology
Neural Crest/*cytology
Receptors, Glucocorticoid/*genetics
Transcription Factor HES-1/*genetics
Actins/genetics ; Animals ; Cell Differentiation ; Cell Nucleus/metabolism ; Cells, Cultured ; Chondrocytes/metabolism ; Collagen Type II/genetics ; Dexamethasone/pharmacology ; MSX1 Transcription Factor/metabolism ; Mice ; Mice, Transgenic ; Mouse Embryonic Stem Cells/metabolism ; Myocytes, Smooth Muscle/metabolism ; NIH 3T3 Cells ; Neural Crest/metabolism ; Promoter Regions, Genetic ; Protein Transport/drug effects ; Recombinant Fusion Proteins/metabolism ; SOX9 Transcription Factor/metabolism ; SOXB1 Transcription Factors/metabolism ; Snail Family Transcription Factors/metabolism ; Transcription Factor HES-1/metabolism

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 19.

Tytuł:: miR-1297 regulates neural stem cell differentiation and viability through controlling Hes1 expression.
Autorzy:: Zheng J; Department of Neruology, The second hospital of Harbin Medical University, Harbin, Heilong Jiang, 150086, China.
Yi D; Department of Pharmacology, Rush University Medical Center, Chicago, IL, 60607, USA.
Shi X; Department of Neruology, The second hospital of Harbin Medical University, Harbin, Heilong Jiang, 150086, China.
Shi H; Department of Neurosurgery, The first hospital of Harbin Medical University, Harbin, Heilong Jiang, 150001, China.; Pokaż więcej
Źródło:: Cell proliferation [Cell Prolif] 2017 Aug; Vol. 50 (4). Date of Electronic Publication: 2017 May 02.
Typ publikacji:: Journal Article
MeSH Terms:: MicroRNAs/*metabolism
Neural Stem Cells/*metabolism
Transcription Factor HES-1/*metabolism
3' Untranslated Regions ; Animals ; Base Sequence ; Cell Differentiation ; Cell Proliferation ; Cell Survival ; Cells, Cultured ; Down-Regulation ; Embryo, Mammalian/cytology ; Immunohistochemistry ; MicroRNAs/genetics ; Neural Stem Cells/cytology ; Rats ; Sequence Alignment ; Transcription Factor HES-1/chemistry ; Transcription Factor HES-1/genetics ; Tubulin/metabolism ; Up-Regulation

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 20.

Tytuł:: Olig2 and Hes regulatory dynamics during motor neuron differentiation revealed by single cell transcriptomics.
Autorzy:: Sagner A; The Francis Crick Institute, London, United Kingdom.
Gaber ZB; Department of Neurobiology, Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, David Geffen School of Medicine at UCLA, University of California, Los Angeles, Los Angeles, California, United States of America.
Delile J; The Francis Crick Institute, London, United Kingdom.
Kong JH; Department of Neurobiology, Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, David Geffen School of Medicine at UCLA, University of California, Los Angeles, Los Angeles, California, United States of America.
Rousso DL; Department of Neurobiology, Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, David Geffen School of Medicine at UCLA, University of California, Los Angeles, Los Angeles, California, United States of America.
Pearson CA; Department of Neurobiology, Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, David Geffen School of Medicine at UCLA, University of California, Los Angeles, Los Angeles, California, United States of America.
Weicksel SE; Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, Michigan, United States of America.
Melchionda M; The Francis Crick Institute, London, United Kingdom.
Mousavy Gharavy SN; The Francis Crick Institute, London, United Kingdom.
Briscoe J; The Francis Crick Institute, London, United Kingdom.
Novitch BG; Department of Neurobiology, Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, David Geffen School of Medicine at UCLA, University of California, Los Angeles, Los Angeles, California, United States of America.; Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, Michigan, United States of America.; Pokaż więcej
Źródło:: PLoS biology [PLoS Biol] 2018 Feb 01; Vol. 16 (2), pp. e2003127. Date of Electronic Publication: 2018 Feb 01 (Print Publication: 2018).
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Single-Cell Analysis*
Transcriptome*
Basic Helix-Loop-Helix Transcription Factors/*physiology
Cell Cycle/*genetics
Motor Neurons/*cytology
Neurogenesis/*genetics
Oligodendrocyte Transcription Factor 2/*physiology
Repressor Proteins/*physiology
Transcription Factor HES-1/*physiology
Animals ; Basic Helix-Loop-Helix Transcription Factors/genetics ; Fluorescent Dyes/metabolism ; Gene Expression Regulation/physiology ; Genes, Reporter ; Interneurons/cytology ; Mice, Transgenic ; Oligodendrocyte Transcription Factor 2/genetics ; Receptors, Notch/metabolism ; Regulatory Sequences, Nucleic Acid ; Repressor Proteins/genetics ; Signal Transduction ; Transcription Factor HES-1/genetics

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Informacja

Wyszukujesz frazę ""Transcription Factor HES-1"" wg kryterium: Temat

Źródło danych

Ogranicz do:

Ogranicz do bazy

Typ dokumentu

Temat

Wydawca

Publikacja

Język