Temat: "Transcription Factor RelA" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Moderate mechanical stress suppresses chondrocyte ferroptosis in osteoarthritis by regulating NF-κB p65/GPX4 signaling pathway.
Autorzy:: Han J; College of Exercise and Health, Shenyang Sport University, Shenyang, 110100, China.; Department of Sport Rehabilitation, Shanghai University of Sport, Shanghai, 200438, China.
Zhan LN; College of Exercise and Health, Shenyang Sport University, Shenyang, 110100, China.
Huang Y; College of Exercise and Health, Shenyang Sport University, Shenyang, 110100, China.
Guo S; College of Exercise and Health, Shenyang Sport University, Shenyang, 110100, China.
Zhou X; College of Exercise and Health, Shenyang Sport University, Shenyang, 110100, China.
Kapilevich L; Faculty of Physical Education, National Research Tomsk State University, Tomsk, Russia.
Wang Z; College of Exercise and Health, Shenyang Sport University, Shenyang, 110100, China.
Ning K; College of Exercise and Health, Shenyang Sport University, Shenyang, 110100, China.
Sun M; College of Exercise and Health, Shenyang Sport University, Shenyang, 110100, China.
Zhang XA; College of Exercise and Health, Shenyang Sport University, Shenyang, 110100, China. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Mar 01; Vol. 14 (1), pp. 5078. Date of Electronic Publication: 2024 Mar 01.
Typ publikacji:: Journal Article
MeSH Terms:: Ferroptosis*
Osteoarthritis*/metabolism
Osteoarthritis*/pathology
Stress, Mechanical*
Animals ; Rats ; Chondrocytes/metabolism ; Interleukin-1beta/metabolism ; NF-E2-Related Factor 2/metabolism ; NF-kappa B/metabolism ; NF-kappa B/physiology ; Signal Transduction ; Tumor Suppressor Protein p53/metabolism ; X-Ray Microtomography ; Transcription Factor RelA/metabolism ; Transcription Factor RelA/physiology ; Phospholipid Hydroperoxide Glutathione Peroxidase/metabolism ; Phospholipid Hydroperoxide Glutathione Peroxidase/physiology

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Skocz do pozycji: 2.

Tytuł:: Anabolic Steroids Activate the NF-κB Pathway in Porcine Ovarian Putative Stem Cells Independently of the ZIP-9 Receptor.
Autorzy:: Wartalski K; Department of Histology, Jagiellonian University Medical College, Kopernika 7 Street, 31-034 Krakow, Poland.
Wiater J; Department of Histology, Jagiellonian University Medical College, Kopernika 7 Street, 31-034 Krakow, Poland.
Maciak P; Department of Endocrinology, Institute of Zoology and Biomedical Research, Faculty of Biology, Jagiellonian University in Krakow, Gronostajowa 9 Street, 30-387 Krakow, Poland.
Pastuła A; Department of Genetics and Evolutionism, Institute of Zoology and Biomedical Research, Faculty of Biology, Jagiellonian University in Krakow, Gronostajowa 9 Street, 30-387 Krakow, Poland.
Lis GJ; Department of Histology, Jagiellonian University Medical College, Kopernika 7 Street, 31-034 Krakow, Poland.
Samiec M; Department of Reproductive Biotechnology and Cryoconservation, National Research Institute of Animal Production, Krakowska 1 Street, 32-083 Balice, Poland.
Trzcińska M; Department of Reproductive Biotechnology and Cryoconservation, National Research Institute of Animal Production, Krakowska 1 Street, 32-083 Balice, Poland.
Duda M; Department of Endocrinology, Institute of Zoology and Biomedical Research, Faculty of Biology, Jagiellonian University in Krakow, Gronostajowa 9 Street, 30-387 Krakow, Poland.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Feb 29; Vol. 25 (5). Date of Electronic Publication: 2024 Feb 29.
Typ publikacji:: Journal Article
MeSH Terms:: NF-kappa B*/metabolism
Anabolic Androgenic Steroids*
Swine ; Animals ; Transcription Factor RelA/metabolism ; NF-KappaB Inhibitor alpha/metabolism ; Phosphorylation

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Skocz do pozycji: 3.

Tytuł:: RvD1 n-3 DPA Downregulates the Transcription of Pro-Inflammatory Genes in Oral Epithelial Cells and Reverses Nuclear Translocation of Transcription Factor p65 after TNF-α Stimulation.
Autorzy:: Balta MG; Institute of Oral Biology, University of Oslo, 0316 Oslo, Norway.
Schreurs O; Institute of Oral Biology, University of Oslo, 0316 Oslo, Norway.
Halder R; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 4367 Belvaux, Luxembourg.
Küntziger TM; Institute of Oral Biology, University of Oslo, 0316 Oslo, Norway.
Saetre F; Department of Pathology, Oslo University Hospital, 0316 Oslo, Norway.
Blix IJS; Institute of Oral Biology, University of Oslo, 0316 Oslo, Norway.; Institute of Clinical Dentistry, Faculty of Dentistry, University of Oslo, 0455 Oslo, Norway.
Baekkevold ES; Institute of Oral Biology, University of Oslo, 0316 Oslo, Norway.; Department of Pathology, Oslo University Hospital, 0316 Oslo, Norway.
Glaab E; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 4367 Belvaux, Luxembourg.
Schenck K; Institute of Oral Biology, University of Oslo, 0316 Oslo, Norway.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2022 Nov 28; Vol. 23 (23). Date of Electronic Publication: 2022 Nov 28.
Typ publikacji:: Journal Article
MeSH Terms:: Transcription Factor RelA*/genetics
Transcription Factor RelA*/metabolism
Tumor Necrosis Factor-alpha*/metabolism
Humans ; NF-kappa B/metabolism ; Active Transport, Cell Nucleus ; Inflammation/genetics ; Inflammation/metabolism ; Epithelial Cells/metabolism

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Skocz do pozycji: 4.

Tytuł:: Gold Nanoparticles Downregulate IL-6 Expression/Production by Upregulating microRNA-26a-5p and Deactivating the RelA and NF-κBp50 Transcription Pathways in Activated Breast Cancer Cells.
Autorzy:: Farhana A; Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Jouf University, Sakaka 72388, Saudi Arabia.
Alsrhani A; Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Jouf University, Sakaka 72388, Saudi Arabia.
Alghsham RS; Department of Pathology, College of Medicine, Qassim University, Buraidah 51452, Saudi Arabia.
Derafa W; Department of Chemistry, College of Science, Jouf University, Aljouf 72388, Saudi Arabia.
Khan YS; Department of Anatomy, College of Medicine, Jouf University, Sakaka 72388, Saudi Arabia.
Rasheed Z; Department of Pathology, College of Medicine, Qassim University, Buraidah 51452, Saudi Arabia.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Jan 24; Vol. 25 (3). Date of Electronic Publication: 2024 Jan 24.
Typ publikacji:: Journal Article
MeSH Terms:: Breast Neoplasms*/drug therapy
Breast Neoplasms*/genetics
Breast Neoplasms*/pathology
Metal Nanoparticles*/chemistry
MicroRNAs*/genetics
MicroRNAs*/metabolism
NF-kappa B*/drug effects
NF-kappa B*/metabolism
Female ; Humans ; 3' Untranslated Regions ; Gold ; Interleukin-6/genetics ; Interleukin-6/metabolism ; Transcription Factor RelA/drug effects ; Transcription Factor RelA/metabolism

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Skocz do pozycji: 5.

Tytuł:: The positive regulatory loop of TCF4N/p65 promotes glioblastoma tumourigenesis and chemosensitivity.
Autorzy:: Hu Y; Department of Laboratory Medicine, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, Jiangsu, China.; Center of Clinical Research, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, Jiangsu, China.; Center for Translational Medicine, Jiangnan University, Wuxi, Jiangsu, China.
Zhang B; Department of Laboratory Medicine, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, Jiangsu, China.; Center of Clinical Research, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, Jiangsu, China.; Center for Translational Medicine, Jiangnan University, Wuxi, Jiangsu, China.
Lu P; Center for Translational Medicine, Jiangnan University, Wuxi, Jiangsu, China.; Department of Medical Oncology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, Jiangsu, China.
Wang J; Department of Laboratory Medicine, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, Jiangsu, China.; Clinical Laboratory, Taixing People's Hospital, Taizhou, Jiangsu, China.
Chen C; Department of Laboratory Medicine, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, Jiangsu, China.; Center of Clinical Research, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, Jiangsu, China.
Yin Y; Department of Laboratory Medicine, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, Jiangsu, China.; Center of Clinical Research, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, Jiangsu, China.; Center for Translational Medicine, Jiangnan University, Wuxi, Jiangsu, China.
Wan Q; Department of Neurosurgery, The Affiliated Wuxi Second People's Hospital of Nanjing Medical University, Wuxi, Jiangsu, China.
Wang J; Department of Laboratory Medicine, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, Jiangsu, China.; Center of Clinical Research, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, Jiangsu, China.; Center for Translational Medicine, Jiangnan University, Wuxi, Jiangsu, China.
Jiao J; Department of Neurosurgery, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, Jiangsu, China.
Fang X; Department of Radiology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, Jiangsu, China.
Pu Z; Department of Laboratory Medicine, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, Jiangsu, China.; Center of Clinical Research, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, Jiangsu, China.; Center for Translational Medicine, Jiangnan University, Wuxi, Jiangsu, China.
Gong L; Department of Laboratory Medicine, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, Jiangsu, China.; Center of Clinical Research, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, Jiangsu, China.; Center for Translational Medicine, Jiangnan University, Wuxi, Jiangsu, China.
Ji L; Department of Laboratory Medicine, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, Jiangsu, China.; Center of Clinical Research, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, Jiangsu, China.; Center for Translational Medicine, Jiangnan University, Wuxi, Jiangsu, China.
Zhu L; Center of Clinical Research, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, Jiangsu, China.; Center for Translational Medicine, Jiangnan University, Wuxi, Jiangsu, China.
Zhang R; Department of Neurosurgery, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, Jiangsu, China.
Zhang J; Wuxi Cancer Institute, Affiliated Hospital of Jiangnan University, Wuxi, Jiangsu, China.
Yang X; Center of Clinical Research, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, Jiangsu, China.
Wang Q; Department of Neurosurgery, The Affiliated Wuxi Second People's Hospital of Nanjing Medical University, Wuxi, Jiangsu, China.
Huang Z; Center for Translational Medicine, Jiangnan University, Wuxi, Jiangsu, China.; Wuxi Cancer Institute, Affiliated Hospital of Jiangnan University, Wuxi, Jiangsu, China.
Zou J; Department of Laboratory Medicine, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, Jiangsu, China.; Center of Clinical Research, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, Jiangsu, China.; Center for Translational Medicine, Jiangnan University, Wuxi, Jiangsu, China.; Pokaż więcej
Źródło:: Clinical and translational medicine [Clin Transl Med] 2022 Sep; Vol. 12 (9), pp. e1042.
Typ publikacji:: Journal Article
MeSH Terms:: Central Nervous System Neoplasms*/drug therapy
Central Nervous System Neoplasms*/genetics
Central Nervous System Neoplasms*/metabolism
Glioblastoma*/drug therapy
Glioblastoma*/genetics
Glioblastoma*/metabolism
Transcription Factor 7-Like 2 Protein*/genetics
Transcription Factor 7-Like 2 Protein*/metabolism
Transcription Factor RelA*/genetics
Transcription Factor RelA*/metabolism
Carcinogenesis/genetics ; Cell Line, Tumor ; Cell Transformation, Neoplastic ; Cell-Penetrating Peptides ; Drug Resistance, Neoplasm/genetics ; Drug Resistance, Neoplasm/physiology ; Humans ; Luciferases ; NF-kappa B/genetics ; NF-kappa B/metabolism ; beta Catenin

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Skocz do pozycji: 6.

Tytuł:: Alleviating effect of Nexrutine on mucosal inflammation in mice with ulcerative colitis: Involvement of the RELA suppression.
Autorzy:: Xu H; Graduate School, Heilongjiang University of Chinese Medicine, Harbin, Heilongjiang, China.
Wu C; Department of Continuing Education, First Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, Heilongjiang, China.
Wang D; Graduate School, Heilongjiang University of Chinese Medicine, Harbin, Heilongjiang, China.
Wang H; Department of Liver, Spleen and Stomach, First Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, Heilongjiang, China.; Pokaż więcej
Źródło:: Immunity, inflammation and disease [Immun Inflamm Dis] 2024 Jan; Vol. 12 (1), pp. e1147.
Typ publikacji:: Journal Article
MeSH Terms:: Colitis, Ulcerative*/chemically induced
Colitis, Ulcerative*/drug therapy
Plant Extracts*
Humans ; Animals ; Mice ; Mesalamine ; Cytokines ; Inflammation/drug therapy ; Transcription Factor RelA/genetics

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Skocz do pozycji: 7.

Tytuł:: Ligustrazine inhibits inflammatory response of human endometrial stromal cells through the STAT3/IGF2BP1/RELA axis.
Autorzy:: Feng Y; The Second Affiliated Hospital of Nanchang University, Nanchang, P.R. China.
Dong H; Department of Obstetrics and Gynecology, Gynecology Women and Children's Hospital of Jinzhou, Jinzhou, P.R. China.
Zheng L; Department of Obstetrics and Gynecology, ShangRao Guangxin District Traditional Chinese Medicine Hospital, Shangrao, P.R. China.; Pokaż więcej
Źródło:: Pharmaceutical biology [Pharm Biol] 2023 Dec; Vol. 61 (1), pp. 666-673.
Typ publikacji:: Journal Article
MeSH Terms:: Tumor Necrosis Factor-alpha*/metabolism
Interleukin-6*/metabolism
Female ; Humans ; Inflammation/metabolism ; RNA, Messenger/metabolism ; RNA/metabolism ; Stromal Cells ; STAT3 Transcription Factor/metabolism ; Transcription Factor RelA/metabolism

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Skocz do pozycji: 8.

Tytuł:: Uterine tumours with myogenic differentiation harbouring SRF::RELA fusions.
Autorzy:: Li Y; Department of Pathology, Fudan University Shanghai Cancer Center, Shanghai, China.; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.
Huang D; Department of Pathology, Fudan University Shanghai Cancer Center, Shanghai, China.; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.
Bi R; Department of Pathology, Fudan University Shanghai Cancer Center, Shanghai, China.; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.
Yao Q; Department of Pathology, Fudan University Shanghai Cancer Center, Shanghai, China.; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.
Ge L; Department of Pathology, Fudan University Shanghai Cancer Center, Shanghai, China.; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.; Department of Pathology, The Third Hospital of Xiamen, Xiamen, China.
Yu L; Department of Pathology, Fudan University Shanghai Cancer Center, Shanghai, China.; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.
Zhou X; Department of Pathology, Fudan University Shanghai Cancer Center, Shanghai, China.; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.
Yang W; Department of Pathology, Fudan University Shanghai Cancer Center, Shanghai, China.; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.; Pokaż więcej
Źródło:: Histopathology [Histopathology] 2022 Oct; Vol. 81 (4), pp. 477-485. Date of Electronic Publication: 2022 Aug 03.
Typ publikacji:: Journal Article
MeSH Terms:: Myofibroma*/pathology
Oncogene Proteins, Fusion*/genetics
Serum Response Factor*/genetics
Transcription Factor RelA*/genetics
Uterine Neoplasms*/genetics
Uterine Neoplasms*/pathology
Biomarkers, Tumor/genetics ; Female ; Gene Fusion ; Humans ; Immunohistochemistry

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Skocz do pozycji: 9.

Tytuł:: Tongxinluo-pretreated mesenchymal stem cells facilitate cardiac repair via exosomal transfer of miR-146a-5p targeting IRAK1/NF-κB p65 pathway.
Autorzy:: Xiong Y; State Key Laboratory of Cardiovascular Disease, Department of Cardiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 10037, China.
Tang R; State Key Laboratory of Cardiovascular Disease, Department of Cardiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 10037, China.
Xu J; State Key Laboratory of Cardiovascular Disease, Department of Cardiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 10037, China.
Jiang W; State Key Laboratory of Cardiovascular Disease, Department of Cardiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 10037, China.
Gong Z; State Key Laboratory of Cardiovascular Disease, Department of Cardiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 10037, China.
Zhang L; State Key Laboratory of Cardiovascular Disease, Department of Cardiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 10037, China.
Ning Y; State Key Laboratory of Cardiovascular Disease, Department of Cardiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 10037, China.
Huang P; State Key Laboratory of Cardiovascular Disease, Department of Cardiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 10037, China.
Xu J; State Key Laboratory of Cardiovascular Disease, Department of Cardiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 10037, China.
Chen G; State Key Laboratory of Cardiovascular Disease, Department of Cardiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 10037, China.
Li X; State Key Laboratory of Cardiovascular Disease, Department of Cardiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 10037, China.
Hu M; State Key Laboratory of Cardiovascular Disease, Department of Cardiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 10037, China.
Xu J; State Key Laboratory of Cardiovascular Disease, Department of Cardiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 10037, China.
Wu C; State Key Laboratory of Cardiovascular Disease, Department of Cardiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 10037, China.
Jin C; State Key Laboratory of Cardiovascular Disease, Department of Cardiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 10037, China.
Li X; State Key Laboratory of Cardiovascular Disease, Department of Cardiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 10037, China.
Qian H; State Key Laboratory of Cardiovascular Disease, Department of Cardiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 10037, China.
Yang Y; State Key Laboratory of Cardiovascular Disease, Department of Cardiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 10037, China. .; Pokaż więcej
Źródło:: Stem cell research & therapy [Stem Cell Res Ther] 2022 Jul 07; Vol. 13 (1), pp. 289. Date of Electronic Publication: 2022 Jul 07.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Exosomes*/metabolism
Interleukin-1 Receptor-Associated Kinases*/metabolism
Mesenchymal Stem Cells*/metabolism
MicroRNAs*/genetics
Myocardial Infarction*/genetics
Myocardial Infarction*/pathology
Myocardial Infarction*/therapy
Transcription Factor RelA*/metabolism
Animals ; Drugs, Chinese Herbal ; Rats ; Stroke Volume ; Ventricular Function, Left

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Skocz do pozycji: 10.

Tytuł:: Fibroblast growth factor 21 improves lipopolysaccharide-induced pulmonary microvascular endothelial cell dysfunction and inflammatory response through SIRT1-mediated NF-κB deacetylation.
Autorzy:: Zhou X; Department of Pediatrics, Affiliated Hospital of Jiangnan University, Wuxi 214122, Jiangsu, China.
Wang X; Department of Respiratory Medicine, The Affiliated Wuxi No. 2 People's Hospital of Nanjing Medical University, Wuxi 214002, Jiangsu, China.
Lu L; Department of Pediatrics, Affiliated Hospital of Jiangnan University, Wuxi 214122, Jiangsu, China.
Deng M; Department of Pediatrics, Affiliated Hospital of Jiangnan University, Wuxi 214122, Jiangsu, China.
Shi X; Department of Pediatrics, The People's Hospital of Suichang County, Lishui 323300, Zhejiang, China.; Pokaż więcej
Źródło:: Canadian journal of physiology and pharmacology [Can J Physiol Pharmacol] 2022 Jun 01; Vol. 100 (6), pp. 492-499. Date of Electronic Publication: 2022 Apr 08.
Typ publikacji:: Journal Article
MeSH Terms:: Fibroblast Growth Factors*/pharmacology
Sirtuin 1*/metabolism
Transcription Factor RelA*/metabolism
Cells, Cultured ; Endothelial Cells/metabolism ; Humans ; Lipopolysaccharides/adverse effects ; NF-kappa B/metabolism ; Recombinant Proteins/pharmacology

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Skocz do pozycji: 11.

Tytuł:: Enhanced transcriptional heterogeneity mediated by NF-κB super-enhancers.
Autorzy:: Wibisana JN; Laboratory for Cell Systems, Institute for Protein Research, Osaka University, Yamadaoka, Suita, Osaka, Japan.
Inaba T; Cellular Informatics Laboratory, RIKEN, Wako, Saitama, Japan.
Shinohara H; RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan.
Yumoto N; RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan.
Hayashi T; Laboratory for Bioinformatics Research, RIKEN Center for Biosystems Dynamics Research, Kobe, Hyogo, Japan.
Umeda M; Laboratory for Bioinformatics Research, RIKEN Center for Biosystems Dynamics Research, Kobe, Hyogo, Japan.
Ebisawa M; Laboratory for Bioinformatics Research, RIKEN Center for Biosystems Dynamics Research, Kobe, Hyogo, Japan.
Nikaido I; Laboratory for Bioinformatics Research, RIKEN Center for Biosystems Dynamics Research, Kobe, Hyogo, Japan.; Functional Genome Informatics, Medical Research Institute, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo, Japan.; Master's/Doctoral Program in Life Science Innovation (Bioinformatics), Degree Programs in Systems and Information Engineering, Graduate School of Science and Technology, University of Tsukuba, Bunkyo-ku, Tokyo, Japan.
Sako Y; Cellular Informatics Laboratory, RIKEN, Wako, Saitama, Japan.
Okada M; Laboratory for Cell Systems, Institute for Protein Research, Osaka University, Yamadaoka, Suita, Osaka, Japan.; RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan.; Center for Drug Design and Research, National Institutes of Biomedical Innovation, Health and Nutrition, Ibaraki, Osaka, Japan.; Pokaż więcej
Źródło:: PLoS genetics [PLoS Genet] 2022 Jun 01; Vol. 18 (6), pp. e1010235. Date of Electronic Publication: 2022 Jun 01 (Print Publication: 2022).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: NF-kappa B*/genetics
NF-kappa B*/metabolism
Transcription Factor RelA*/genetics
Cell Nucleus/metabolism ; Gene Expression Regulation ; Protein Binding ; Regulatory Sequences, Nucleic Acid ; Transcriptional Activation

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Skocz do pozycji: 12.

Tytuł:: NFκB (RelA) mediates transactivation of hnRNPD in oral cancer cells.
Autorzy:: Kumar V; Department of Biochemistry, All India Institute of Medical Sciences, New Delhi, India.
Kumar A; Department of Biochemistry, All India Institute of Medical Sciences, New Delhi, India.
Kumar M; Department of Biochemistry, All India Institute of Medical Sciences, Bilaspur, India.
Lone MR; Department of Biochemistry, All India Institute of Medical Sciences, New Delhi, India.
Mishra D; Division of Oral Pathology, Centre for Dental Education and Research, All India Institute of Medical Sciences, New Delhi, India.
Chauhan SS; Department of Biochemistry, All India Institute of Medical Sciences, New Delhi, India. s_s_.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2022 Apr 08; Vol. 12 (1), pp. 5944. Date of Electronic Publication: 2022 Apr 08.
Typ publikacji:: Journal Article
MeSH Terms:: Carcinoma, Squamous Cell*/genetics
Heterogeneous Nuclear Ribonucleoprotein D0*/genetics
Mouth Neoplasms*/genetics
Transcription Factor RelA*/genetics
Transcription Factor RelA*/metabolism
Base Sequence ; Humans ; Luciferases ; NF-kappa B/genetics ; NF-kappa B/metabolism ; Transcriptional Activation

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Skocz do pozycji: 13.

Tytuł:: C11orf95-RELA, YAP1-MAMLD1, and YAP1-FAM118B Fusion Negative Anaplastic Ependymoma with Lipogenic Differentiation.
Autorzy:: Jha S; Department of Pathology and Lab Medicine, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India.
Mulgulwar PB; Department of Pathology, All India Institute of Medical Sciences, New Delhi, India.
Sharma MC; Department of Pathology and Lab Medicine, All India Institute of Medical Sciences, New Delhi, India.
Purkait S; Department of Pathology and Lab Medicine, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India.
Pattnaik A; Department of Neurosurgery, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India.
Sable MN; Department of Pathology and Lab Medicine, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India.; Pokaż więcej
Źródło:: Neurology India [Neurol India] 2023 Sep-Oct; Vol. 71 (5), pp. 1011-1014.
Typ publikacji:: Case Reports
MeSH Terms:: Supratentorial Neoplasms*
Ependymoma*/genetics
Ependymoma*/pathology
Female ; Humans ; Middle Aged ; Transcription Factor RelA/metabolism ; Immunohistochemistry ; DNA-Binding Proteins ; Nuclear Proteins ; Transcription Factors/genetics ; Proteins

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Skocz do pozycji: 14.

Tytuł:: Voacanga globosa Spirobisindole Alkaloids Exert Antiviral Activity in HIV Latently Infected Cell Lines by Targeting the NF-kB Cascade: In Vitro and In Silico Investigations.
Autorzy:: de Jesus MSM; The Graduate School, University of Santo Tomas, España Blvd., Manila 1015, Philippines.; Department of Biological Sciences, College of Science, University of Santo Tomas, España Blvd., Manila 1015, Philippines.
Macabeo APG; Laboratory for Organic Reactivity, Discovery and Synthesis (LORDS), Research Center for Natural and Applied Sciences, University of Santo Tomas, España Blvd., Manila 1015, Philippines.
Ramos JDA; The Graduate School, University of Santo Tomas, España Blvd., Manila 1015, Philippines.; Department of Biological Sciences, College of Science, University of Santo Tomas, España Blvd., Manila 1015, Philippines.; Molecular Diagnostics and Therapeutics Laboratory, Research Center for Natural and Applied Sciences, University of Santo Tomas, España Blvd., Manila 1015, Philippines.
de Leon VNO; Department of Biological Sciences, College of Science, University of Santo Tomas, España Blvd., Manila 1015, Philippines.; Laboratory for Organic Reactivity, Discovery and Synthesis (LORDS), Research Center for Natural and Applied Sciences, University of Santo Tomas, España Blvd., Manila 1015, Philippines.
Asamitsu K; Department of Molecular and Cellular Biology, Graduate School of Medical Sciences, Nagoya City University, Nagoya 4678601, Japan.
Okamoto T; Department of Molecular and Cellular Biology, Graduate School of Medical Sciences, Nagoya City University, Nagoya 4678601, Japan.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2022 Feb 05; Vol. 27 (3). Date of Electronic Publication: 2022 Feb 05.
Typ publikacji:: Journal Article
MeSH Terms:: Alkaloids/*pharmacology
HIV Infections/*metabolism
HIV-1/*physiology
I-kappa B Kinase/*metabolism
NF-kappa B p50 Subunit/*metabolism
Transcription Factor RelA/*metabolism
Voacanga/*chemistry
Alkaloids/chemistry ; Cell Line ; Dose-Response Relationship, Drug ; HIV Infections/drug therapy ; HIV-1/drug effects ; HL-60 Cells ; Humans ; I-kappa B Kinase/chemistry ; Indole Alkaloids/pharmacology ; Models, Biological ; Molecular Docking Simulation ; NF-kappa B/metabolism ; NF-kappa B p50 Subunit/chemistry ; Plant Extracts/chemistry ; Signal Transduction/drug effects ; Spiro Compounds/pharmacology ; Transcription Factor RelA/chemistry ; Tumor Necrosis Factor-alpha/pharmacology ; Virus Latency/drug effects ; Virus Replication/drug effects

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Skocz do pozycji: 15.

Tytuł:: A new p65 isoform that bind the glucocorticoid hormone and is expressed in inflammation liver diseases and COVID-19.
Autorzy:: Spinelli G; Istituto per la Ricerca e l'Innovazione Biomedica del Consiglio Nazionale delle Ricerche, Via Ugo La Malfa 153, 90146, Palermo, Italy.; Dipartimento Scienze e Tecnologie Biologiche Chimiche e Farmaceutiche, Università degli Studi di Palermo, Viale Delle Scienze, ed. 16, 90128, Palermo, Italy.
Biddeci G; Istituto per la Ricerca e l'Innovazione Biomedica del Consiglio Nazionale delle Ricerche, Via Ugo La Malfa 153, 90146, Palermo, Italy.
Artale A; Istituto per la Ricerca e l'Innovazione Biomedica del Consiglio Nazionale delle Ricerche, Via Ugo La Malfa 153, 90146, Palermo, Italy.
Valentino F; Istituto per la Ricerca e l'Innovazione Biomedica del Consiglio Nazionale delle Ricerche, Via Ugo La Malfa 153, 90146, Palermo, Italy.
Tarantino G; Dipartimento di Medicina Specialistica, Diagnostica e Sperimentale, Università di Bologna, Via Massarenti 9, 40138, Bologna, Italy.
Gallo G; Dipartimento Scienze e Tecnologie Biologiche Chimiche e Farmaceutiche, Università degli Studi di Palermo, Viale Delle Scienze, ed. 16, 90128, Palermo, Italy.
Gianguzza F; Dipartimento Scienze e Tecnologie Biologiche Chimiche e Farmaceutiche, Università degli Studi di Palermo, Viale Delle Scienze, ed. 16, 90128, Palermo, Italy.
Conaldi PG; Dipartimento di Ricerca, IRCCS-ISMETT, Istituto Mediterraneo per i Trapianti e Terapie ad alta Specializzazione, Via Tricomi 5, 90127, Palermo, Italy.
Corrao S; Unità COVID, Dipartimento di Medicina Interna, Azienda Ospedaliera di Rilevanza Nazionale e Alta Specializzazione ARNAS Civico, Di Cristina, Benfratelli, 90127, Palermo, Italy.; Dipartimento PROMISE, Università degli Studi di Palermo, 90100, Palermo, Italy.
Gervasi F; Laboratorio Specialistico di Oncologia, Rilevanza Nazionale e Alta Specializzazione Ospedaliera Trust ARNAS Civico, Di Cristina, Benfratelli, 90127, Palermo, Italy.
Aronica TS; Unità Organizzativa Complessa di Patologia Clinica, Rilevanza Nazionale e Alta Specializzazione ARNAS Civico, Di Cristina, Benfratelli, 90127, Palermo, Italy.
Di Leonardo A; Dipartimento Scienze e Tecnologie Biologiche Chimiche e Farmaceutiche, Università degli Studi di Palermo, Viale Delle Scienze, ed. 16, 90128, Palermo, Italy.
Duro G; Istituto per la Ricerca e l'Innovazione Biomedica del Consiglio Nazionale delle Ricerche, Via Ugo La Malfa 153, 90146, Palermo, Italy.
Di Blasi F; Istituto per la Ricerca e l'Innovazione Biomedica del Consiglio Nazionale delle Ricerche, Via Ugo La Malfa 153, 90146, Palermo, Italy. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2021 Nov 25; Vol. 11 (1), pp. 22913. Date of Electronic Publication: 2021 Nov 25.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Inflammation/*immunology
Receptors, Glucocorticoid/*metabolism
Transcription Factor RelA/*metabolism
Adrenal Cortex Hormones/metabolism ; Adult ; Alternative Splicing ; Animals ; COVID-19/immunology ; Carcinoma, Hepatocellular/metabolism ; Dexamethasone/metabolism ; Female ; Gene Expression/genetics ; Gene Expression Regulation/genetics ; Glucocorticoids/metabolism ; Hepatitis/metabolism ; Humans ; Inflammation/metabolism ; Leukocytes, Mononuclear/metabolism ; Liver/metabolism ; Liver Diseases/immunology ; Liver Neoplasms/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Middle Aged ; NF-kappa B/metabolism ; Protein Isoforms ; Receptors, Glucocorticoid/immunology ; SARS-CoV-2/pathogenicity ; Transcription Factor RelA/immunology ; Transcription Factor RelA/physiology

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Skocz do pozycji: 16.

Tytuł:: lncRNA H19 Aggravates Brain Injury in Rats following Experimental Intracerebral Hemorrhage via NF- κ B Pathway.
Autorzy:: Mao S; Department of Neurosurgery, Shanghai Tenth People's Hospital Chongming Branch, Shanghai 202157, China.
Huang H; Department of Neurosurgery, Shanghai Tenth People's Hospital Chongming Branch, Shanghai 202157, China.
Chen X; Department of Neurosurgery, Shanghai Tenth People's Hospital, Shanghai 200072, China.; Pokaż więcej
Źródło:: Computational and mathematical methods in medicine [Comput Math Methods Med] 2022 Jan 15; Vol. 2022, pp. 3017312. Date of Electronic Publication: 2022 Jan 15 (Print Publication: 2022).
Typ publikacji:: Journal Article; Retracted Publication
MeSH Terms:: Brain Injuries/*etiology
Brain Injuries/*genetics
Cerebral Hemorrhage/*complications
Cerebral Hemorrhage/*genetics
RNA, Long Noncoding/*genetics
Transcription Factor RelA/*metabolism
Animals ; Biomarkers/metabolism ; Brain/metabolism ; Brain Injuries/metabolism ; Cerebral Hemorrhage/metabolism ; Computational Biology ; Disease Models, Animal ; Genetic Markers ; Inflammation Mediators/metabolism ; Male ; Oxidative Stress ; RNA, Long Noncoding/antagonists & inhibitors ; RNA, Long Noncoding/metabolism ; RNA, Small Interfering/genetics ; Rats ; Rats, Sprague-Dawley ; Signal Transduction/genetics ; Transcription Factor RelA/genetics

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Skocz do pozycji: 17.

Tytuł:: Mechanisms underlying antidepressant effect of transcutaneous auricular vagus nerve stimulation on CUMS model rats based on hippocampal α7nAchR/NF-κB signal pathway.
Autorzy:: Wang JY; Department of Physiology, Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Dongcheng District, No.16 Dongzhimen Nan Xiao Street, Beijing, 100700, China.
Zhang Y; Department of Physiology, Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Dongcheng District, No.16 Dongzhimen Nan Xiao Street, Beijing, 100700, China.
Chen Y; Department of Physiology, Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Dongcheng District, No.16 Dongzhimen Nan Xiao Street, Beijing, 100700, China.
Wang Y; Department of Physiology, Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Dongcheng District, No.16 Dongzhimen Nan Xiao Street, Beijing, 100700, China.
Li SY; Department of Physiology, Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Dongcheng District, No.16 Dongzhimen Nan Xiao Street, Beijing, 100700, China.
Wang YF; Department of Physiology, Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Dongcheng District, No.16 Dongzhimen Nan Xiao Street, Beijing, 100700, China.
Zhang ZX; Department of Physiology, Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Dongcheng District, No.16 Dongzhimen Nan Xiao Street, Beijing, 100700, China.
Zhang J; Department of Physiology, Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Dongcheng District, No.16 Dongzhimen Nan Xiao Street, Beijing, 100700, China.
Rong P; Department of Physiology, Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Dongcheng District, No.16 Dongzhimen Nan Xiao Street, Beijing, 100700, China. .; Pokaż więcej
Źródło:: Journal of neuroinflammation [J Neuroinflammation] 2021 Dec 17; Vol. 18 (1), pp. 291. Date of Electronic Publication: 2021 Dec 17.
Typ publikacji:: Journal Article
MeSH Terms:: Depressive Disorder, Major/*metabolism
Hippocampus/*metabolism
Stress, Psychological/*metabolism
Transcription Factor RelA/*metabolism
Vagus Nerve Stimulation/*methods
alpha7 Nicotinic Acetylcholine Receptor/*metabolism
Animals ; Chronic Disease ; Depressive Disorder, Major/genetics ; Depressive Disorder, Major/therapy ; Gene Knockout Techniques/methods ; Hippocampus/drug effects ; Male ; Nicotinic Antagonists/administration & dosage ; Rats ; Rats, Sprague-Dawley ; Rats, Transgenic ; Stress, Psychological/genetics ; Stress, Psychological/therapy ; Transcription Factor RelA/genetics ; alpha7 Nicotinic Acetylcholine Receptor/antagonists & inhibitors ; alpha7 Nicotinic Acetylcholine Receptor/genetics

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Skocz do pozycji: 18.

Tytuł:: Zinc finger protein A20 regulates the development and progression of osteoarthritis by affecting the activity of NF-κB p65.
Autorzy:: Cui SB; The First Department of Orthopedics, Handan Central Hospital, Handan, China.
Wang TX; Department of Nephrology, Affiliated Hospital of Hebei University of Technology, Handan, China.
Liu ZW; The First Department of Orthopedics, Handan Central Hospital, Handan, China.
Yan JY; The First Department of Orthopedics, Handan Central Hospital, Handan, China.
Zhang K; The First Department of Orthopedics, Handan Central Hospital, Handan, China.; Pokaż więcej
Źródło:: Immunopharmacology and immunotoxicology [Immunopharmacol Immunotoxicol] 2021 Dec; Vol. 43 (6), pp. 713-723. Date of Electronic Publication: 2021 Aug 31.
Typ publikacji:: Journal Article
MeSH Terms:: Disease Progression*
Osteoarthritis/*metabolism
Osteoarthritis/*pathology
Transcription Factor RelA/*metabolism
Tumor Necrosis Factor alpha-Induced Protein 3/*metabolism
Zinc Fingers/*physiology
Animals ; Cells, Cultured ; Down-Regulation/physiology ; Female ; Humans ; Male ; Mice ; Mice, Inbred C57BL ; Transcription Factor RelA/antagonists & inhibitors

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Skocz do pozycji: 19.

Tytuł:: NF‑κB is negatively associated with Nurr1 to reduce the inflammatory response in Parkinson's disease.
Autorzy:: Gao H; Department of Neurology, Second Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang 830063, P.R. China.
Wang D; Department of Neurology, Second Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang 830063, P.R. China.
Jiang S; Department of Neurology, Second Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang 830063, P.R. China.
Mao J; Department of Neurology, Urumqi Friendship Hospital, Urumqi, Xinjiang 830049, P.R. China.
Yang X; Department of Neurology, Second Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang 830063, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2021 Jun; Vol. 23 (6). Date of Electronic Publication: 2021 Mar 31.
Typ publikacji:: Journal Article
MeSH Terms:: Nuclear Receptor Subfamily 4, Group A, Member 2/*metabolism
Parkinson Disease/*metabolism
Transcription Factor RelA/*metabolism
Animals ; Interleukin-1beta/genetics ; Interleukin-1beta/metabolism ; Interleukin-6/genetics ; Interleukin-6/metabolism ; Lipopolysaccharides/toxicity ; Nuclear Receptor Subfamily 4, Group A, Member 2/genetics ; PC12 Cells ; Quinazolines/pharmacology ; Rats ; Synucleins/genetics ; Synucleins/metabolism ; Transcription Factor RelA/antagonists & inhibitors ; Transcription Factor RelA/genetics ; Tumor Necrosis Factor-alpha/genetics ; Tumor Necrosis Factor-alpha/metabolism ; Tyrosine 3-Monooxygenase/genetics ; Tyrosine 3-Monooxygenase/metabolism

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Skocz do pozycji: 20.

Tytuł:: Nuclear factor kappa B inhibitor suppresses experimental autoimmune neuritis in mice via declining macrophages polarization to M1 type.
Autorzy:: Shen D; Neuroscience Center, Department of Neurology, The First Hospital of Jilin University, Changchun, China.; Neuroscience Center, Department of Neurology, Qingdao Municipal Hospital, Qingdao, China.
Chu F; Neuroscience Center, Department of Neurology, The First Hospital of Jilin University, Changchun, China.; Department of Neurobiology, Care Sciences and Society, Division of Neurogeriatrics, Karolinska Institute, Karolinska University Hospital Solna, Stockholm, Sweden.
Lang Y; Neuroscience Center, Department of Neurology, The First Hospital of Jilin University, Changchun, China.
Zheng C; Neuroscience Center, Department of Neurology, The First Hospital of Jilin University, Changchun, China.
Li C; Neuroscience Center, Department of Neurology, The First Hospital of Jilin University, Changchun, China.
Liu K; Neuroscience Center, Department of Neurology, The First Hospital of Jilin University, Changchun, China.
Zhu J; Neuroscience Center, Department of Neurology, The First Hospital of Jilin University, Changchun, China.; Department of Neurobiology, Care Sciences and Society, Division of Neurogeriatrics, Karolinska Institute, Karolinska University Hospital Solna, Stockholm, Sweden.; Pokaż więcej
Źródło:: Clinical and experimental immunology [Clin Exp Immunol] 2021 Oct; Vol. 206 (1), pp. 110-117. Date of Electronic Publication: 2021 Jul 06.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Guillain-Barre Syndrome*/drug therapy
Guillain-Barre Syndrome*/immunology
Neuritis, Autoimmune, Experimental*/drug therapy
Neuritis, Autoimmune, Experimental*/immunology
Macrophages/*immunology
Nitriles/*pharmacology
Sulfones/*pharmacology
Transcription Factor RelA/*antagonists & inhibitors
Animals ; Male ; Mice ; Transcription Factor RelA/immunology

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