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Wyszukujesz frazę ""Transdifferentiation"" wg kryterium: Temat


Tytuł:
Fucoxanthin inhibits cardiac fibroblast transdifferentiation by alleviating oxidative stress through downregulation of BRD4.
Autorzy:
Han J; Shaoxing Seventh People's Hospital, Shaoxing, China.
Zhang Y; Shaoxing Seventh People's Hospital, Shaoxing, China.
Peng H; Department of pharmacology, Medical college, Shaoxing University, Shaoxing, China.
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Źródło:
PloS one [PLoS One] 2023 Sep 12; Vol. 18 (9), pp. e0291469. Date of Electronic Publication: 2023 Sep 12 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cell Transdifferentiation*
Nuclear Proteins*/genetics
Angiotensin II/pharmacology ; Down-Regulation ; Fibroblasts ; Kelch-Like ECH-Associated Protein 1/genetics ; NF-E2-Related Factor 2/genetics ; NFI Transcription Factors ; Oxidative Stress ; Reactive Oxygen Species ; Animals ; Rats
Czasopismo naukowe
Tytuł:
Low glutaminase and glycolysis correlate with a high transdifferentiation efficiency in mouse cortex.
Autorzy:
Li Y; Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, GIBH-CUHK Joint Research Laboratory on Stem Cell and Regenerative Medicine, Centre for Regenerative Medicine and Health, Hong Kong Institute of Science & Innovation, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China.
Yang T; Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, GIBH-CUHK Joint Research Laboratory on Stem Cell and Regenerative Medicine, Centre for Regenerative Medicine and Health, Hong Kong Institute of Science & Innovation, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China.; University of Chinese Academy of Sciences, Beijing, China.
Cheng Y; Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, GIBH-CUHK Joint Research Laboratory on Stem Cell and Regenerative Medicine, Centre for Regenerative Medicine and Health, Hong Kong Institute of Science & Innovation, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China.
Hou J; Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, GIBH-CUHK Joint Research Laboratory on Stem Cell and Regenerative Medicine, Centre for Regenerative Medicine and Health, Hong Kong Institute of Science & Innovation, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China.; Department of Plastic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Liu Z; Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, GIBH-CUHK Joint Research Laboratory on Stem Cell and Regenerative Medicine, Centre for Regenerative Medicine and Health, Hong Kong Institute of Science & Innovation, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China.
Zhao Y; Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, GIBH-CUHK Joint Research Laboratory on Stem Cell and Regenerative Medicine, Centre for Regenerative Medicine and Health, Hong Kong Institute of Science & Innovation, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China.
Chen S; Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, GIBH-CUHK Joint Research Laboratory on Stem Cell and Regenerative Medicine, Centre for Regenerative Medicine and Health, Hong Kong Institute of Science & Innovation, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China.; University of Chinese Academy of Sciences, Beijing, China.
Qin Z; Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, GIBH-CUHK Joint Research Laboratory on Stem Cell and Regenerative Medicine, Centre for Regenerative Medicine and Health, Hong Kong Institute of Science & Innovation, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China.; University of Chinese Academy of Sciences, Beijing, China.
Wang C; Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, GIBH-CUHK Joint Research Laboratory on Stem Cell and Regenerative Medicine, Centre for Regenerative Medicine and Health, Hong Kong Institute of Science & Innovation, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China.; Department of Plastic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Song W; Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, GIBH-CUHK Joint Research Laboratory on Stem Cell and Regenerative Medicine, Centre for Regenerative Medicine and Health, Hong Kong Institute of Science & Innovation, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China.; University of Chinese Academy of Sciences, Beijing, China.
Ge H; Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, GIBH-CUHK Joint Research Laboratory on Stem Cell and Regenerative Medicine, Centre for Regenerative Medicine and Health, Hong Kong Institute of Science & Innovation, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China.; Joint School of Life Sciences, Guangzhou Medical University, Guangzhou, China.
Li C; Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, GIBH-CUHK Joint Research Laboratory on Stem Cell and Regenerative Medicine, Centre for Regenerative Medicine and Health, Hong Kong Institute of Science & Innovation, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China.
Liang L; Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, GIBH-CUHK Joint Research Laboratory on Stem Cell and Regenerative Medicine, Centre for Regenerative Medicine and Health, Hong Kong Institute of Science & Innovation, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China.
Guo L; Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, GIBH-CUHK Joint Research Laboratory on Stem Cell and Regenerative Medicine, Centre for Regenerative Medicine and Health, Hong Kong Institute of Science & Innovation, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China.
Sun H; Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, GIBH-CUHK Joint Research Laboratory on Stem Cell and Regenerative Medicine, Centre for Regenerative Medicine and Health, Hong Kong Institute of Science & Innovation, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China.
Wu LP; Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, GIBH-CUHK Joint Research Laboratory on Stem Cell and Regenerative Medicine, Centre for Regenerative Medicine and Health, Hong Kong Institute of Science & Innovation, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China.; University of Chinese Academy of Sciences, Beijing, China.
Zheng H; Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, GIBH-CUHK Joint Research Laboratory on Stem Cell and Regenerative Medicine, Centre for Regenerative Medicine and Health, Hong Kong Institute of Science & Innovation, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China.; University of Chinese Academy of Sciences, Beijing, China.; Joint School of Life Sciences, Guangzhou Medical University, Guangzhou, China.; Institutes for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing, China.
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Źródło:
Cell proliferation [Cell Prolif] 2023 May; Vol. 56 (5), pp. e13422. Date of Electronic Publication: 2023 Feb 14.
Typ publikacji:
Journal Article
MeSH Terms:
Cell Transdifferentiation*/physiology
Glutaminase*/metabolism
Mice ; Animals ; Swine ; Cells, Cultured ; Astrocytes/metabolism ; Glycolysis
Czasopismo naukowe
Tytuł:
Subtype Transdifferentiation in Human Cancer: The Power of Tissue Plasticity in Tumor Progression.
Autorzy:
Fedele M; Institute of Experimental Endocrinology and Oncology 'G. Salvatore' (IEOS), National Research Council-CNR, 80131 Naples, Italy.
Cerchia L; Institute of Experimental Endocrinology and Oncology 'G. Salvatore' (IEOS), National Research Council-CNR, 80131 Naples, Italy.
Battista S; Institute of Experimental Endocrinology and Oncology 'G. Salvatore' (IEOS), National Research Council-CNR, 80131 Naples, Italy.
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Źródło:
Cells [Cells] 2024 Feb 17; Vol. 13 (4). Date of Electronic Publication: 2024 Feb 17.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Adenocarcinoma*
Pancreatic Neoplasms*
Breast Neoplasms*/pathology
Male ; Humans ; Cell Transdifferentiation ; Neoplastic Processes ; Tumor Microenvironment/genetics
Czasopismo naukowe
Tytuł:
Expression profiling of stemness markers in testicular germline stem cells from neonatal and adult Swiss albino mice during their transdifferentiation in vitro.
Autorzy:
Indu S; Rajiv Gandhi Centre for Biotechnology, Thycaud PO, Poojappura, Thiruvananthapuram, 695 014, Kerala, India.
Devi AN; Rajiv Gandhi Centre for Biotechnology, Thycaud PO, Poojappura, Thiruvananthapuram, 695 014, Kerala, India.
Sahadevan M; Rajiv Gandhi Centre for Biotechnology, Thycaud PO, Poojappura, Thiruvananthapuram, 695 014, Kerala, India.
Sengottaiyan J; Rajiv Gandhi Centre for Biotechnology, Thycaud PO, Poojappura, Thiruvananthapuram, 695 014, Kerala, India.; Department of Biotechnology, University of Kerala, Karyavattom Campus, Thiruvananthapuram, 695581, Kerala, India.
Basu A; Rajiv Gandhi Centre for Biotechnology, Thycaud PO, Poojappura, Thiruvananthapuram, 695 014, Kerala, India.; Department of Biotechnology, University of Kerala, Karyavattom Campus, Thiruvananthapuram, 695581, Kerala, India.
K SR; Rajiv Gandhi Centre for Biotechnology, Thycaud PO, Poojappura, Thiruvananthapuram, 695 014, Kerala, India.; Department of Biotechnology, University of Kerala, Karyavattom Campus, Thiruvananthapuram, 695581, Kerala, India.
Kumar PG; Rajiv Gandhi Centre for Biotechnology, Thycaud PO, Poojappura, Thiruvananthapuram, 695 014, Kerala, India. .; Department of Biotechnology, University of Kerala, Karyavattom Campus, Thiruvananthapuram, 695581, Kerala, India. .
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Źródło:
Stem cell research & therapy [Stem Cell Res Ther] 2024 Apr 01; Vol. 15 (1), pp. 93. Date of Electronic Publication: 2024 Apr 01.
Typ publikacji:
Journal Article
MeSH Terms:
Testis*/metabolism
Spermatogonia*
Male ; Mice ; Animals ; Cell Transdifferentiation ; Cells, Cultured ; Stem Cells/metabolism
Czasopismo naukowe
Tytuł:
Repressing miR-23a promotes the transdifferentiation of pancreatic α cells to β cells via negatively regulating the expression of SDF-1α.
Autorzy:
Lang H; Department of General Medicine, Chengdu Second People's Hospital, Chengdu, Sichuan Province, China.
Lin N; Department of Clinical Nutrition, the General Hospital of Western Theater Command, Chengdu, Sichuan Province, China.
Chen X; Department of General Medicine, Chengdu Second People's Hospital, Chengdu, Sichuan Province, China.; College of Medicine of Southwest Jiaotong University, Chengdu, Sichuan Province, China.
Xiang J; Department of General Medicine, Chengdu Second People's Hospital, Chengdu, Sichuan Province, China.; College of Medicine of Southwest Jiaotong University, Chengdu, Sichuan Province, China.
Zhang X; Department of General Medicine, Chengdu Second People's Hospital, Chengdu, Sichuan Province, China.
Kang C; Department of Clinical Nutrition, the General Hospital of Western Theater Command, Chengdu, Sichuan Province, China.
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Źródło:
PloS one [PLoS One] 2024 Mar 22; Vol. 19 (3), pp. e0299821. Date of Electronic Publication: 2024 Mar 22 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Glucagon-Secreting Cells*/metabolism
Insulin-Secreting Cells*/metabolism
MicroRNAs*/genetics
MicroRNAs*/metabolism
Animals ; Mice ; Cell Transdifferentiation/genetics ; Chemokine CXCL12/genetics ; Chemokine CXCL12/metabolism ; Glucagon
Czasopismo naukowe
Tytuł:
Direct Reprogramming of Resident Non-Myocyte Cells and Its Potential for In Vivo Cardiac Regeneration.
Autorzy:
Perveen S; Department of Clinical and Biological Sciences, University of Turin, 10043 Orbassano, Italy.
Vanni R; Department of Clinical and Biological Sciences, University of Turin, 10043 Orbassano, Italy.
Lo Iacono M; Department of Clinical and Biological Sciences, University of Turin, 10043 Orbassano, Italy.
Rastaldo R; Department of Clinical and Biological Sciences, University of Turin, 10043 Orbassano, Italy.
Giachino C; Department of Clinical and Biological Sciences, University of Turin, 10043 Orbassano, Italy.
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Źródło:
Cells [Cells] 2023 Apr 15; Vol. 12 (8). Date of Electronic Publication: 2023 Apr 15.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Cellular Reprogramming Techniques*
Heart*/physiology
Regeneration*
Heart Diseases*/therapy
Fibroblasts*/cytology
Fibroblasts*/physiology
Cell Transdifferentiation*
Cellular Reprogramming*
Pericytes*/cytology
Pericytes*/physiology
Myocytes, Cardiac/cytology ; Myocytes, Cardiac/physiology ; Endothelial Cells/cytology ; Endothelial Cells/physiology ; Humans ; Animals
Czasopismo naukowe
Tytuł:
Genomics of sexual cell fate transdifferentiation in the mouse gonad.
Autorzy:
Murphy MW; Developmental Biology Center and Department of Genetics, Cell Biology, and Development, University of Minnesota, Minneapolis, MN 55455, USA.
Gearhart MD; Developmental Biology Center and Department of Genetics, Cell Biology, and Development, University of Minnesota, Minneapolis, MN 55455, USA.
Wheeler A; Developmental Biology Center and Department of Genetics, Cell Biology, and Development, University of Minnesota, Minneapolis, MN 55455, USA.
Bardwell VJ; Developmental Biology Center and Department of Genetics, Cell Biology, and Development, University of Minnesota, Minneapolis, MN 55455, USA.; University of Minnesota Masonic Cancer Center, Minneapolis, MN 55455, USA.
Zarkower D; Developmental Biology Center and Department of Genetics, Cell Biology, and Development, University of Minnesota, Minneapolis, MN 55455, USA.; University of Minnesota Masonic Cancer Center, Minneapolis, MN 55455, USA.
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Źródło:
G3 (Bethesda, Md.) [G3 (Bethesda)] 2022 Dec 01; Vol. 12 (12).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Cell Transdifferentiation*/genetics
Gonadal Dysgenesis*/metabolism
Animals ; Female ; Humans ; Male ; Mice ; Chromatin/genetics ; Chromatin/metabolism ; Genomics ; Gonads/metabolism ; Sex Determination Processes ; Testis/metabolism ; Transcription Factors/genetics ; Transcription Factors/metabolism
Czasopismo naukowe
Tytuł:
Fibroblast p90RSK induces epithelial transdifferentiation through oxidative stress-mediated β-catenin pathway.
Autorzy:
Shi C; Division of Nephrology, Department of Medicine, Penn State University College of Medicine, Hershey, Pennsylvania, USA.
Lin L; Division of Nephrology, Department of Medicine, Penn State University College of Medicine, Hershey, Pennsylvania, USA.
Hu K; Division of Nephrology, Department of Medicine, Penn State University College of Medicine, Hershey, Pennsylvania, USA.; Department of Cellular and Molecular Physiology, Penn State University College of Medicine, Hershey, Pennsylvania, USA.
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Źródło:
Clinical and translational medicine [Clin Transl Med] 2023 Jan; Vol. 13 (1), pp. e1128.
Typ publikacji:
Letter; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
beta Catenin*/genetics
beta Catenin*/metabolism
Cell Transdifferentiation*
Ribosomal Protein S6 Kinases, 90-kDa/metabolism ; Fibroblasts/metabolism ; Oxidative Stress
Raport
Tytuł:
Tumor Neurobiology in the Pathogenesis and Therapy of Head and Neck Cancer.
Autorzy:
Liang S; Department of Otorhinolaryngology, Head and Neck Tumors, Heidelberg University Hospital, 69120 Heidelberg, Germany.
Hess J; Department of Otorhinolaryngology, Head and Neck Tumors, Heidelberg University Hospital, 69120 Heidelberg, Germany.; Research Group Molecular Mechanisms of Head and Neck Tumors, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
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Źródło:
Cells [Cells] 2024 Jan 30; Vol. 13 (3). Date of Electronic Publication: 2024 Jan 30.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Head and Neck Neoplasms*/therapy
Nerve Tissue*
Humans ; Cell Transdifferentiation
Czasopismo naukowe
Tytuł:
Hepatocyte GPCR signaling regulates IRF3 to control hepatic stellate cell transdifferentiation.
Autorzy:
Yu JH; College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, 08826, Republic of Korea.
Choi MG; College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, 08826, Republic of Korea.
Lee NY; College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, 08826, Republic of Korea.
Kwon A; College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, 08826, Republic of Korea.
Lee E; College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, 08826, Republic of Korea.
Koo JH; College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, 08826, Republic of Korea. .
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Źródło:
Cell communication and signaling : CCS [Cell Commun Signal] 2024 Jan 17; Vol. 22 (1), pp. 48. Date of Electronic Publication: 2024 Jan 17.
Typ publikacji:
Video-Audio Media; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Hepatic Stellate Cells*
Interleukin-33*/metabolism
Humans ; Interferon Regulatory Factor-3/metabolism ; Cell Transdifferentiation ; Culture Media, Conditioned ; Glucagon/metabolism ; Hepatocytes/metabolism ; Liver Cirrhosis/metabolism ; Fibrosis
Czasopismo naukowe
Tytuł:
Osteogenic transdifferentiation of primary human fibroblasts to osteoblast-like cells with human platelet lysate.
Autorzy:
Cayami FK; Department of Human Genetics, Amsterdam UMC, Amsterdam Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.; Center for Biomedical Research (CEBIOR), Faculty of Medicine, Diponegoro University, Jln Prof Soedarto SH, 50275, Semarang, Indonesia.
Claeys L; Department of Human Genetics, Amsterdam UMC, Amsterdam Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
de Ruiter R; Department of Internal Medicine, Section Endocrinology, Amsterdam UMC, Amsterdam Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Smilde BJ; Department of Internal Medicine, Section Endocrinology, Amsterdam UMC, Amsterdam Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Wisse L; Department of Human Genetics, Amsterdam UMC, Amsterdam Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Bogunovic N; Department of Human Genetics, Amsterdam UMC, Amsterdam Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Riesebos E; Department of Human Genetics, Amsterdam UMC, Amsterdam Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Eken L; Department of Human Genetics, Amsterdam UMC, Amsterdam Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Kooi I; Department of Human Genetics, Amsterdam UMC, Amsterdam Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Sistermans EA; Department of Human Genetics, Amsterdam UMC, Amsterdam Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Bravenboer N; Department of Clinical Chemistry, Amsterdam UMC, Amsterdam Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Pals G; Department of Human Genetics, Amsterdam UMC, Amsterdam Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Faradz SMH; Center for Biomedical Research (CEBIOR), Faculty of Medicine, Diponegoro University, Jln Prof Soedarto SH, 50275, Semarang, Indonesia.
Sie D; Department of Human Genetics, Amsterdam UMC, Amsterdam Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Eekhoff EMW; Department of Internal Medicine, Section Endocrinology, Amsterdam UMC, Amsterdam Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Micha D; Department of Human Genetics, Amsterdam UMC, Amsterdam Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands. .
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Źródło:
Scientific reports [Sci Rep] 2022 Aug 29; Vol. 12 (1), pp. 14686. Date of Electronic Publication: 2022 Aug 29.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cell Transdifferentiation*/genetics
Osteoblasts*/metabolism
Calcification, Physiologic/genetics ; Cell Differentiation/genetics ; Fibroblasts ; Humans ; Osteogenesis/genetics
Czasopismo naukowe
Tytuł:
Pancreatic Transdifferentiation Using β-Cell Transcription Factors for Type 1 Diabetes Treatment.
Autorzy:
Mahoney ALG; School of Life Sciences, University of Technology Sydney, Sydney 2007, Australia.
Nassif NT; School of Life Sciences, University of Technology Sydney, Sydney 2007, Australia.
O'Brien BA; School of Life Sciences, University of Technology Sydney, Sydney 2007, Australia.
Simpson AM; School of Life Sciences, University of Technology Sydney, Sydney 2007, Australia.
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Źródło:
Cells [Cells] 2022 Jul 08; Vol. 11 (14). Date of Electronic Publication: 2022 Jul 08.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Cell Transdifferentiation*/genetics
Diabetes Mellitus, Type 1*/genetics
Diabetes Mellitus, Type 1*/therapy
Insulin-Secreting Cells*
Cellular Reprogramming Techniques/methods ; Humans ; Insulin ; Transcription Factors/genetics
Czasopismo naukowe
Tytuł:
NF-κB-dependent secretome of senescent cells can trigger neuroendocrine transdifferentiation of breast cancer cells.
Autorzy:
Raynard C; Centre de Recherche en Cancérologie de Lyon, Inserm U1052, CNRS UMR 5286, Centre Léon Bérard, Université de Lyon, Lyon, France.
Ma X; Centre de Recherche en Cancérologie de Lyon, Inserm U1052, CNRS UMR 5286, Centre Léon Bérard, Université de Lyon, Lyon, France.; Department of Intensive Care, The Affiliated Hospital of Yangzhou University, Yangzhou University, Yangzhou, China.
Huna A; Centre de Recherche en Cancérologie de Lyon, Inserm U1052, CNRS UMR 5286, Centre Léon Bérard, Université de Lyon, Lyon, France.
Tessier N; University of Lyon, CarMeN Laboratory, INSERM, INRA, INSA Lyon, Université Claude Bernard Lyon 1, Bron, France.
Massemin A; Centre de Recherche en Cancérologie de Lyon, Inserm U1052, CNRS UMR 5286, Centre Léon Bérard, Université de Lyon, Lyon, France.
Zhu K; Centre de Recherche en Cancérologie de Lyon, Inserm U1052, CNRS UMR 5286, Centre Léon Bérard, Université de Lyon, Lyon, France.
Flaman JM; Centre de Recherche en Cancérologie de Lyon, Inserm U1052, CNRS UMR 5286, Centre Léon Bérard, Université de Lyon, Lyon, France.
Moulin F; University of Lyon, CarMeN Laboratory, INSERM, INRA, INSA Lyon, Université Claude Bernard Lyon 1, Bron, France.
Goehrig D; Centre de Recherche en Cancérologie de Lyon, Inserm U1052, CNRS UMR 5286, Centre Léon Bérard, Université de Lyon, Lyon, France.
Medard JJ; Centre de Recherche en Cancérologie de Lyon, Inserm U1052, CNRS UMR 5286, Centre Léon Bérard, Université de Lyon, Lyon, France.
Vindrieux D; Centre de Recherche en Cancérologie de Lyon, Inserm U1052, CNRS UMR 5286, Centre Léon Bérard, Université de Lyon, Lyon, France.
Treilleux I; Centre de Recherche en Cancérologie de Lyon, Inserm U1052, CNRS UMR 5286, Centre Léon Bérard, Université de Lyon, Lyon, France.
Hernandez-Vargas H; Centre de Recherche en Cancérologie de Lyon, Inserm U1052, CNRS UMR 5286, Centre Léon Bérard, Université de Lyon, Lyon, France.
Ducreux S; University of Lyon, CarMeN Laboratory, INSERM, INRA, INSA Lyon, Université Claude Bernard Lyon 1, Bron, France.
Martin N; Centre de Recherche en Cancérologie de Lyon, Inserm U1052, CNRS UMR 5286, Centre Léon Bérard, Université de Lyon, Lyon, France.
Bernard D; Centre de Recherche en Cancérologie de Lyon, Inserm U1052, CNRS UMR 5286, Centre Léon Bérard, Université de Lyon, Lyon, France.
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Źródło:
Aging cell [Aging Cell] 2022 Jul; Vol. 21 (7), pp. e13632. Date of Electronic Publication: 2022 Jun 02.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Breast Neoplasms*/metabolism
Cell Transdifferentiation*/physiology
NF-kappa B*/metabolism
Aged ; Cellular Senescence/genetics ; Cellular Senescence/physiology ; Humans ; Male ; Neuroendocrine Cells/cytology ; Neuroendocrine Cells/metabolism ; Secretome
Czasopismo naukowe
Tytuł:
The Emerging Role of Cell Transdifferentiation in Skeletal Development and Diseases.
Autorzy:
Wang K; Department of Biomedical Sciences, Texas A&M University College of Dentistry, Dallas, TX 75246, USA.; Division of Orthodontics, University of Connecticut Health Center, Farmington, CT 06030, USA.
Ma C; Center for Excellence in Hip, Scottish Rite for Children, Dallas, TX 75219, USA.; Department of Orthopaedic Surgery, UT Southwestern Medical Center, Dallas, TX 75390, USA.
Feng JQ; Department of Biomedical Sciences, Texas A&M University College of Dentistry, Dallas, TX 75246, USA.
Jing Y; Department of Orthodontics, Texas A&M University College of Dentistry, Dallas, TX 75246, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 May 26; Vol. 23 (11). Date of Electronic Publication: 2022 May 26.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Cell Transdifferentiation*
Osteogenesis*/physiology
Cartilage/metabolism ; Cell Differentiation/physiology ; Chondrocytes/metabolism ; Chondrogenesis/physiology
Czasopismo naukowe
Tytuł:
Regulation of cell proliferation and transdifferentiation compensates for ventilator-induced lung injury mediated by NLRP3 inflammasome activation.
Autorzy:
Liu H; Department of Anesthesiology, Qilu Hospital of Shandong University, Ji'nan, China.
Yang X; Department of Ophtalmology, Jinan Second People's Hospital, Ji'nan, China.
Liu G; Department of Ophtalmology, Qilu Hospital of Shandong University, Ji'nan, China.
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Źródło:
Immunity, inflammation and disease [Immun Inflamm Dis] 2023 Oct; Vol. 11 (10), pp. e1062.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Inflammasomes*/metabolism
Ventilator-Induced Lung Injury*/metabolism
Ventilator-Induced Lung Injury*/pathology
Humans ; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism ; NLR Proteins ; Cell Transdifferentiation ; Cell Proliferation
Czasopismo naukowe
Tytuł:
BMP-2 Long-Term Stimulation of Human Pre-Osteoblasts Induces Osteogenic Differentiation and Promotes Transdifferentiation and Bone Remodeling Processes.
Autorzy:
Ingwersen LC; Biomechanics and Implant Technology Research Laboratory, Department of Orthopaedics, Rostock University Medical Center, 18057 Rostock, Germany.
Frank M; Medical Biology and Electron Microscopic Center, Rostock University Medical Center, 18057 Rostock, Germany.; Department of Life, Light and Matter, University of Rostock, 18059 Rostock, Germany.
Naujokat H; Department of Oral and Maxillofacial Surgery, University Hospital of Schleswig-Holstein, 24105 Kiel, Germany.
Loger K; Department of Oral and Maxillofacial Surgery, University Hospital of Schleswig-Holstein, 24105 Kiel, Germany.
Bader R; Biomechanics and Implant Technology Research Laboratory, Department of Orthopaedics, Rostock University Medical Center, 18057 Rostock, Germany.
Jonitz-Heincke A; Biomechanics and Implant Technology Research Laboratory, Department of Orthopaedics, Rostock University Medical Center, 18057 Rostock, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Mar 12; Vol. 23 (6). Date of Electronic Publication: 2022 Mar 12.
Typ publikacji:
Journal Article
MeSH Terms:
Cell Transdifferentiation*
Osteogenesis*
Alkaline Phosphatase/metabolism ; Animals ; Bone Morphogenetic Protein 2/metabolism ; Bone Remodeling ; Cell Differentiation ; Cells, Cultured ; Humans ; Osteoblasts/metabolism ; PPAR gamma/genetics ; PPAR gamma/metabolism
Czasopismo naukowe
Tytuł:
Fibroblast transition to an endothelial "trans" state improves cell reprogramming efficiency.
Autorzy:
Mathison M; Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX, USA.
Sanagasetti D; Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX, USA.
Singh VP; Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX, USA.
Pugazenthi A; Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX, USA.
Pinnamaneni JP; Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX, USA.
Ryan CT; Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX, USA.
Yang J; Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX, USA.
Rosengart TK; Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX, USA. .
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Źródło:
Scientific reports [Sci Rep] 2021 Nov 19; Vol. 11 (1), pp. 22605. Date of Electronic Publication: 2021 Nov 19.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Cell Transdifferentiation*
Cellular Reprogramming*
Endothelium/*metabolism
Fibroblasts/*metabolism
Animals ; Animals, Newborn ; Cell Plasticity ; Cell Separation ; Coculture Techniques ; Endothelial Cells/metabolism ; Flow Cytometry ; Humans ; Myocytes, Cardiac/metabolism ; Prevalence ; Rats
Czasopismo naukowe
Tytuł:
Myofibroblast transdifferentiation is associated with changes in cellular and extracellular vesicle miRNA abundance.
Autorzy:
Zainal Abidin SAI; Department of Oral and Craniofacial Sciences, Faculty of Dentistry, University of Malaya, Kuala Lumpur, Malaysia.; Oral Cancer Research & Coordinating Center, Faculty of Dentistry, University of Malaya, Kuala Lumpur, Malaysia.; Integrated Biosciences, School of Clinical Dentistry, University of Sheffield, Sheffield, United Kingdom.
Paterson IC; Department of Oral and Craniofacial Sciences, Faculty of Dentistry, University of Malaya, Kuala Lumpur, Malaysia.; Oral Cancer Research & Coordinating Center, Faculty of Dentistry, University of Malaya, Kuala Lumpur, Malaysia.
Hunt S; Integrated Biosciences, School of Clinical Dentistry, University of Sheffield, Sheffield, United Kingdom.
Lambert DW; Integrated Biosciences, School of Clinical Dentistry, University of Sheffield, Sheffield, United Kingdom.
Higginbotham S; Integrated Biosciences, School of Clinical Dentistry, University of Sheffield, Sheffield, United Kingdom.; Kroto Research Institute, University of Sheffield, Sheffield, United Kingdom.
Pink RC; Department of Biological and Medical Science, Faculty of Health and Life Sciences, Oxford Brookes University, Oxford, United Kingdom.
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Źródło:
PloS one [PLoS One] 2021 Nov 11; Vol. 16 (11), pp. e0256812. Date of Electronic Publication: 2021 Nov 11 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cell Transdifferentiation/*physiology
Extracellular Vesicles/*metabolism
MicroRNAs/*metabolism
Myofibroblasts/*cytology
Actins/metabolism ; Cell Transdifferentiation/drug effects ; Cells, Cultured ; Collagen/metabolism ; Extracellular Vesicles/drug effects ; Gene Expression Profiling ; Humans ; MicroRNAs/genetics ; Myofibroblasts/drug effects ; Myofibroblasts/metabolism ; Phosphatidylinositol 3-Kinases/metabolism ; Signal Transduction/physiology ; Transforming Growth Factor beta1/pharmacology
Czasopismo naukowe
Tytuł:
Erythropoietin (EPO) as a Key Regulator of Erythropoiesis, Bone Remodeling and Endothelial Transdifferentiation of Multipotent Mesenchymal Stem Cells (MSCs): Implications in Regenerative Medicine.
Autorzy:
Tsiftsoglou AS; Laboratory of Pharmacology, Department of Pharmaceutical Sciences, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
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Źródło:
Cells [Cells] 2021 Aug 20; Vol. 10 (8). Date of Electronic Publication: 2021 Aug 20.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Bone Remodeling/*physiology
Cell Transdifferentiation/*physiology
Endothelial Cells/*cytology
Erythropoiesis/*physiology
Erythropoietin/*metabolism
Mesenchymal Stem Cells/*cytology
Multipotent Stem Cells/*cytology
Bone Remodeling/drug effects ; Cell Transdifferentiation/drug effects ; Erythropoiesis/drug effects ; Erythropoietin/pharmacology ; Humans ; Receptors, Erythropoietin/metabolism ; Regenerative Medicine/methods
Czasopismo naukowe
Tytuł:
GED-0507 attenuates lung fibrosis by counteracting myofibroblast transdifferentiation in vivo and in vitro.
Autorzy:
Speca S; Univ. Lille, INSERM, U1286 -Infinite-Institute for Translational Research in Inflammation, Lille, France.
Dubuquoy C; Intestinal Biotech Development, Lille, France.
Rousseaux C; Intestinal Biotech Development, Lille, France.
Chavatte P; Univ. Lille, INSERM, U1286 -Infinite-Institute for Translational Research in Inflammation, Lille, France.; Laboratoire de Pharmacie Clinique, Faculté des Sciences Pharmaceutiques et Biologiques, Lille, France.
Desreumaux P; Univ. Lille, INSERM, U1286 -Infinite-Institute for Translational Research in Inflammation, Lille, France.; Hepato-Gastroenterology Department, CHU Lille, Lille, France.
Spagnolo P; Respiratory Disease Unit, Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padova, Padova, Italy.
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Źródło:
PloS one [PLoS One] 2021 Sep 16; Vol. 16 (9), pp. e0257281. Date of Electronic Publication: 2021 Sep 16 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cell Transdifferentiation*
Myofibroblasts/*cytology
Propionates/*pharmacology
Pulmonary Fibrosis/*drug therapy
A549 Cells ; Animals ; Bleomycin ; Cell Line ; Cell Survival/drug effects ; Humans ; In Vitro Techniques ; Inflammation ; Lung/drug effects ; Mice ; Mice, Inbred C57BL ; PPAR gamma/metabolism ; Pulmonary Fibrosis/physiopathology ; Treatment Outcome
Czasopismo naukowe

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