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Wyszukujesz frazę ""Translocation, Genetic"" wg kryterium: Temat


Tytuł :
H. pylori negative gastric MALT lymphoma with API2-MALT1 translocation treated by endoscopic submucosal dissection: A case report.
Autorzy :
Tahara T; Third Department of Internal Medicine, Kansai Medical University, Osaka.; Department of Gastroenterology, Fujita Health University School of Medicine, Toyoake, Japan.
Horiguchi N; Department of Gastroenterology, Fujita Health University School of Medicine, Toyoake, Japan.
Terada T; Department of Gastroenterology, Fujita Health University School of Medicine, Toyoake, Japan.
Yoshida D; Department of Gastroenterology, Fujita Health University School of Medicine, Toyoake, Japan.
Okubo M; Department of Gastroenterology, Fujita Health University School of Medicine, Toyoake, Japan.
Funasaka K; Department of Gastroenterology, Fujita Health University School of Medicine, Toyoake, Japan.
Nakagawa Y; Department of Gastroenterology, Fujita Health University School of Medicine, Toyoake, Japan.
Shibata T; Department of Gastroenterology, Fujita Health University School of Medicine, Toyoake, Japan.
Ohmiya N; Department of Gastroenterology, Fujita Health University School of Medicine, Toyoake, Japan.
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Źródło :
Medicine [Medicine (Baltimore)] 2021 Apr 09; Vol. 100 (14), pp. e24371.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Translocation, Genetic*
Lymphoma, B-Cell, Marginal Zone/*genetics
Stomach Neoplasms/*genetics
Helicobacter pylori/genetics ; Humans ; Lymphoma, B-Cell, Marginal Zone/pathology ; Lymphoma, B-Cell, Marginal Zone/surgery ; Male ; Middle Aged ; Oncogene Proteins, Fusion ; Stomach Neoplasms/surgery
Czasopismo naukowe
Tytuł :
Therapy-related Myeloid Leukemia With the Translocation t(8;19)(p11;q13) Leading to a KAT6A-LEUTX Fusion Gene.
Autorzy :
Panagopoulos I; Section for Cancer Cytogenetics, Institute for Cancer Genetics and Informatics, The Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway; .
Andersen K; Section for Cancer Cytogenetics, Institute for Cancer Genetics and Informatics, The Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway.
Ramslien LF; Department of Cancer and Hematological Diseases, Telemark Hospital, Skien, Norway.
Ikonomou IM; Department of Pathology, Oslo University Hospital, Oslo, Norway.
Micci F; Section for Cancer Cytogenetics, Institute for Cancer Genetics and Informatics, The Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway.
Heim S; Section for Cancer Cytogenetics, Institute for Cancer Genetics and Informatics, The Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway.; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.
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Źródło :
Anticancer research [Anticancer Res] 2021 Apr; Vol. 41 (4), pp. 1753-1760.
Typ publikacji :
Case Reports
MeSH Terms :
Chromosomes, Human, Pair 19*
Chromosomes, Human, Pair 8*
Gene Fusion*
Translocation, Genetic*
Biomarkers, Tumor/*genetics
Chemoradiotherapy/*adverse effects
Histone Acetyltransferases/*genetics
Homeodomain Proteins/*genetics
Leukemia, Myeloid, Acute/*etiology
Aged ; Female ; Gene Expression Regulation, Leukemic ; Humans ; Leukemia, Myeloid, Acute/diagnosis ; Leukemia, Myeloid, Acute/drug therapy ; Leukemia, Myeloid, Acute/genetics ; Treatment Outcome ; Uterine Cervical Neoplasms/therapy
Raport
Tytuł :
Xp11 translocation renal cell carcinoma with morphological features mimicking multilocular cystic renal neoplasm of low malignant potential: a series of six cases with molecular analysis.
Autorzy :
Song Y; Pathology, West China Hospital, Sichuan University, Chengdu, China.
Yin X; Pathology, West China Hospital, Sichuan University, Chengdu, China.
Xia Q; Pathology, Nanjing Jinling Hospital, Nanjing, China.
Zheng L; Pathology, West China Hospital, Sichuan University, Chengdu, China.
Yao J; Radiology, West China Hospital, Sichuan University, Chengdu, China.
Zeng H; Urology, West China Hospital, Sichuan University, Chengdu, China.
Nie L; Pathology, West China Hospital, Sichuan University, Chengdu, China.
Gong J; Pathology, West China Hospital, Sichuan University, Chengdu, China.
Zhou Q; Pathology, West China Hospital, Sichuan University, Chengdu, China.
Chen N; Pathology, West China Hospital, Sichuan University, Chengdu, China .
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Źródło :
Journal of clinical pathology [J Clin Pathol] 2021 Mar; Vol. 74 (3), pp. 171-176. Date of Electronic Publication: 2020 Jul 22.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Fusion*
Translocation, Genetic*
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors/*genetics
Carcinoma, Renal Cell/*diagnostic imaging
Chromosomes, Human, X/*genetics
Kidney Neoplasms/*diagnostic imaging
Mediator Complex/*genetics
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors/metabolism ; Carcinoma, Renal Cell/genetics ; Carcinoma, Renal Cell/pathology ; Female ; Gene Rearrangement ; Humans ; Kidney Neoplasms/genetics ; Kidney Neoplasms/pathology ; Male ; Mediator Complex/metabolism
Czasopismo naukowe
Tytuł :
Identification of a novel TNRC18-RARA fusion in acute promyelocytic leukemia lacking t(15;17)(q24;q12)/PML-RARA.
Autorzy :
Wang Z; National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, the First Affiliated Hospital of Soochow University, Soochow University, Suzhou, P.R. China.; Suzhou Jsuniwell Medical Laboratory, Suzhou, P.R. China.
Wen L; National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, the First Affiliated Hospital of Soochow University, Soochow University, Suzhou, P.R. China.
Zhang L; National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, the First Affiliated Hospital of Soochow University, Soochow University, Suzhou, P.R. China.
Xu X; National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, the First Affiliated Hospital of Soochow University, Soochow University, Suzhou, P.R. China.
Chen X; National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, the First Affiliated Hospital of Soochow University, Soochow University, Suzhou, P.R. China.
Yao L; National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, the First Affiliated Hospital of Soochow University, Soochow University, Suzhou, P.R. China.
Wang M; National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, the First Affiliated Hospital of Soochow University, Soochow University, Suzhou, P.R. China.
Shen Z; National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, the First Affiliated Hospital of Soochow University, Soochow University, Suzhou, P.R. China.
Mo G; Department of Hematology, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, P.R. China.
Wang Y; Department of Hematology, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, P.R. China.
Zhao D; Department of Hematology, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, P.R. China.
Cai W; Department of Hematology, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, P.R. China.
Shen J; Department of Hematology, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, P.R. China.
Chi X; Dalian Municipal Friendship Hospital, Dalian, Liaoning, P.R. China.
Xu Y; National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, the First Affiliated Hospital of Soochow University, Soochow University, Suzhou, P.R. China.
Zeng Z; National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, the First Affiliated Hospital of Soochow University, Soochow University, Suzhou, P.R. China.
Pan J; National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, the First Affiliated Hospital of Soochow University, Soochow University, Suzhou, P.R. China.
Ruan C; National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, the First Affiliated Hospital of Soochow University, Soochow University, Suzhou, P.R. China.; Institute of Blood and Marrow Transplantation, Collaborative Innovation Center of Hematology, Soochow University, Suzhou, P.R. China.
Wu D; National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, the First Affiliated Hospital of Soochow University, Soochow University, Suzhou, P.R. China.; Institute of Blood and Marrow Transplantation, Collaborative Innovation Center of Hematology, Soochow University, Suzhou, P.R. China.
Jia Z; Department of Hematology, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, P.R. China.
Chen S; National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, the First Affiliated Hospital of Soochow University, Soochow University, Suzhou, P.R. China.; Institute of Blood and Marrow Transplantation, Collaborative Innovation Center of Hematology, Soochow University, Suzhou, P.R. China.
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Źródło :
Molecular carcinogenesis [Mol Carcinog] 2021 Feb; Vol. 60 (2). Date of Electronic Publication: 2021 Jan 11.
Typ publikacji :
Case Reports; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Translocation, Genetic*
Chromosomes, Human, Pair 15/*genetics
Chromosomes, Human, Pair 17/*genetics
Leukemia, Promyelocytic, Acute/*genetics
Oncogene Proteins, Fusion/*genetics
Retinoic Acid Receptor alpha/*genetics
Gene Expression Regulation, Leukemic ; Humans ; In Situ Hybridization, Fluorescence ; Leukemia, Promyelocytic, Acute/metabolism ; Leukemia, Promyelocytic, Acute/pathology ; Male ; Middle Aged ; Oncogene Proteins, Fusion/metabolism ; Retinoic Acid Receptor alpha/metabolism
Czasopismo naukowe
Tytuł :
Acute myeloid leukemia with a severe coagulopathy and t(8;16)(p11;p13).
Autorzy :
Hastings A; Department of Haematology, Hammersmith Hospital, London, UK.
Apperley JF; Centre for Haematology, Hammersmith Hospital Campus, Imperial College London, London, UK.
Nadal-Melsio E; Specialist Integrated Haematological Malignancy Diagnostic Service, Hammersmith Hospital, London, UK.
Brown L; Specialist Integrated Haematological Malignancy Diagnostic Service, Hammersmith Hospital, London, UK.
Bain BJ; Centre for Haematology, St Mary's Hospital Campus, Imperial College London, St Mary's Hospital, Praed Street, London, UK.
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Źródło :
American journal of hematology [Am J Hematol] 2021 Jan; Vol. 96 (1), pp. 163-164. Date of Electronic Publication: 2020 Jul 28.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Blood Coagulation Disorders*/drug therapy
Blood Coagulation Disorders*/genetics
Blood Coagulation Disorders*/metabolism
Blood Coagulation Disorders*/pathology
Chromosomes, Human, Pair 16*/genetics
Chromosomes, Human, Pair 16*/metabolism
Chromosomes, Human, Pair 8*/genetics
Chromosomes, Human, Pair 8*/metabolism
Leukemia, Myeloid, Acute*/drug therapy
Leukemia, Myeloid, Acute*/genetics
Leukemia, Myeloid, Acute*/metabolism
Leukemia, Myeloid, Acute*/pathology
Translocation, Genetic*
Antineoplastic Combined Chemotherapy Protocols/*administration & dosage
Adult ; Cytarabine/administration & dosage ; Daunorubicin/administration & dosage ; Dexamethasone/administration & dosage ; Gemtuzumab/administration & dosage ; Humans ; Male ; Tretinoin/administration & dosage
Czasopismo naukowe
Tytuł :
A Versatile Protocol to Generate Translocations in Yeast Genomes Using CRISPR/Cas9.
Autorzy :
Agier N; Sorbonne Université, CNRS, Institut de Biologie Paris-Seine, Laboratory of Computational and Quantitative Biology, Paris, France.
Fleiss A; Synthetic Biology Group, MRC London Institute of Medical Sciences, London, UK.; Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London, UK.
Delmas S; Sorbonne Université, CNRS, Institut de Biologie Paris-Seine, Laboratory of Computational and Quantitative Biology, Paris, France.
Fischer G; Sorbonne Université, CNRS, Institut de Biologie Paris-Seine, Laboratory of Computational and Quantitative Biology, Paris, France. .
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Źródło :
Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2021; Vol. 2196, pp. 181-198.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
CRISPR-Cas Systems*
Genome, Fungal*
Translocation, Genetic*
Yeasts/*genetics
Cloning, Molecular ; DNA Shuffling ; Gene Editing ; Gene Order ; Gene Rearrangement ; Genetic Engineering/methods ; Genetic Vectors/genetics ; Plasmids/genetics ; RNA, Guide ; Recombination, Genetic ; Transformation, Genetic
Czasopismo naukowe
Tytuł :
Primary Gastric Synovial Sarcoma in a Child: A Case Report and Review of the Literature.
Autorzy :
Manohar A; Departments of Oncopathology.
Gopal C; Departments of Oncopathology.
Premalata CS; Departments of Oncopathology.
Kumar RV; Departments of Oncopathology.
Patil Okaly GV; Departments of Oncopathology.
Somashekhar SP; Department of Surgical Oncology, Manipal Hospital, Bengaluru, Karnataka, India.
Padma M; Pediatric Oncology, Kidwai Memorial Institute of Oncology.
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Źródło :
Journal of pediatric hematology/oncology [J Pediatr Hematol Oncol] 2021 Jan; Vol. 43 (1), pp. e119-e122.
Typ publikacji :
Case Reports; Journal Article; Review
MeSH Terms :
Translocation, Genetic*
Oncogene Proteins, Fusion/*genetics
Sarcoma, Synovial/*diagnosis
Stomach Neoplasms/*diagnosis
Adolescent ; Humans ; Male ; Prognosis ; Sarcoma, Synovial/genetics ; Stomach Neoplasms/genetics
Czasopismo naukowe
Tytuł :
Epigenetic silencing of miR564 contributes to the leukemogenesis of t(8;21) acute myeloid leukemia.
Autorzy :
Yang E; Department of Hematology and Oncology, International Cancer Center, Shenzhen University General Hospital, Shenzhen University Health Science Center, Xueyuan AVE 1098, Nanshan District, Shenzhen, Guangdong 518000, P.R. China.
Guan W; Department of Hematology, Chinese PLA General Hospital, Beijing 100853, P.R. China.
Gong D; Department of Hematology and Oncology, International Cancer Center, Shenzhen University General Hospital, Shenzhen University Health Science Center, Xueyuan AVE 1098, Nanshan District, Shenzhen, Guangdong 518000, P.R. China.
Gao X; Department of Hematology and Oncology, International Cancer Center, Shenzhen University General Hospital, Shenzhen University Health Science Center, Xueyuan AVE 1098, Nanshan District, Shenzhen, Guangdong 518000, P.R. China.
Han C; Department of Hematology and Oncology, International Cancer Center, Shenzhen University General Hospital, Shenzhen University Health Science Center, Xueyuan AVE 1098, Nanshan District, Shenzhen, Guangdong 518000, P.R. China.
Zhang J; Department of Hematology and Oncology, International Cancer Center, Shenzhen University General Hospital, Shenzhen University Health Science Center, Xueyuan AVE 1098, Nanshan District, Shenzhen, Guangdong 518000, P.R. China.
Wang H; School of Medicine, Nankai University, 94 Weijin Road, Tianjin 300071, P.R. China.
Wang M; Department of Hematology, Chinese PLA General Hospital, Beijing 100853, P.R. China.
Li Y; Central Laboratory, Shenzhen University General Hospital, Xueyuan AVE 1098, Nanshan District, Shenzhen, Guangdong 518000, P.R. China.
Yu L; Department of Hematology and Oncology, International Cancer Center, Shenzhen University General Hospital, Shenzhen University Health Science Center, Xueyuan AVE 1098, Nanshan District, Shenzhen, Guangdong 518000, P.R. China.
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Źródło :
Clinical science (London, England : 1979) [Clin Sci (Lond)] 2020 Dec 11; Vol. 134 (23), pp. 3079-3091.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Epigenesis, Genetic*
Gene Silencing*
Translocation, Genetic*
Carcinogenesis/*genetics
Leukemia, Myeloid, Acute/*genetics
Leukemia, Myeloid, Acute/*pathology
MicroRNAs/*metabolism
Animals ; Apoptosis/genetics ; Base Sequence ; Carcinogenesis/pathology ; Cell Cycle Checkpoints/genetics ; Cell Differentiation/genetics ; Cell Line, Tumor ; Core Binding Factor Alpha 2 Subunit/metabolism ; Cyclin D1/metabolism ; DNA (Cytosine-5-)-Methyltransferases/metabolism ; DNA Methylation/genetics ; Female ; Gene Expression Regulation, Leukemic ; Humans ; Mice, Inbred BALB C ; Mice, Nude ; MicroRNAs/genetics ; Oncogene Proteins, Fusion/metabolism ; Promoter Regions, Genetic/genetics ; Protein Binding/genetics ; RUNX1 Translocation Partner 1 Protein/metabolism ; Up-Regulation/genetics
Czasopismo naukowe
Tytuł :
[Evolvement of a five-way translocation t(5;9;22;6;17) from a four-way Philadelphia translocation t(5;9;22;6) in a rare case of chronic myeloid leukemia].
Autorzy :
Kong S; Peking University Institute of Hematology, Beijing Key Laboratory of Hematopoietic Stem Cell Transplantation, Peking University People's Hospital, Beijing 100044, China. .
Gu Y
Qin Y
Wang Z
Feng L
Jiang Q
Lai Y
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Źródło :
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics [Zhonghua Yi Xue Yi Chuan Xue Za Zhi] 2020 Dec 10; Vol. 37 (12), pp. 1395-1398.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Leukemia, Myelogenous, Chronic, BCR-ABL Positive*/drug therapy
Leukemia, Myelogenous, Chronic, BCR-ABL Positive*/genetics
Philadelphia Chromosome*
Translocation, Genetic*
Enzyme Inhibitors/therapeutic use ; Evolution, Molecular ; Female ; Humans ; In Situ Hybridization, Fluorescence ; Mutation/genetics
Czasopismo naukowe
Tytuł :
RUNX1/ETO and mutant KIT both contribute to programming the transcriptional and chromatin landscape in t(8;21) acute myeloid leukemia.
Autorzy :
Chin PS; Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
Assi SA; Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
Ptasinska A; Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
Imperato MR; Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
Cockerill PN; Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
Bonifer C; Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK. Electronic address: .
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Źródło :
Experimental hematology [Exp Hematol] 2020 Dec; Vol. 92, pp. 62-74. Date of Electronic Publication: 2020 Nov 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Chromosomes, Human, Pair 21*/genetics
Chromosomes, Human, Pair 21*/metabolism
Chromosomes, Human, Pair 8*/genetics
Chromosomes, Human, Pair 8*/metabolism
Leukemia, Myeloid, Acute*/genetics
Leukemia, Myeloid, Acute*/metabolism
Leukemia, Myeloid, Acute*/pathology
Mutation, Missense*
Transcription, Genetic*
Translocation, Genetic*
Chromatin/*metabolism
Core Binding Factor Alpha 2 Subunit/*metabolism
Proto-Oncogene Proteins c-kit/*metabolism
RUNX1 Translocation Partner 1 Protein/*metabolism
Amino Acid Substitution ; Chromatin/pathology ; Core Binding Factor Alpha 2 Subunit/genetics ; Female ; Gene Expression Regulation, Leukemic ; HEK293 Cells ; Humans ; Male ; Proto-Oncogene Proteins c-kit/genetics ; RUNX1 Translocation Partner 1 Protein/genetics
Czasopismo naukowe
Tytuł :
High-grade B-Cell Lymphoma With MYC, BCL2, and/or BCL6 Translocations/Rearrangements: Clinicopathologic Features of 51 Cases in a Single Institution of South China.
Autorzy :
Zhang J; Department of Pathology, Huazhong University of Science and Technology Union Shenzhen Hospital, Shenzhen.
Weng Z; Department of Pathology, The First Affiliated Hospital, Jinan University, Guangzhou, Guangdong Province, China.
Huang Y; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine.; Departments of Pathology.
Li M; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine.; Departments of Pathology.
Wang F; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine.; Molecular Diagnostics.
Wang Y; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine.; Medical Oncology, Sun Yat-sen University Cancer Center.
Rao H; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine.; Departments of Pathology.
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Źródło :
The American journal of surgical pathology [Am J Surg Pathol] 2020 Dec; Vol. 44 (12), pp. 1602-1611.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Rearrangement*
Translocation, Genetic*
Biomarkers, Tumor/*genetics
Lymphoma, B-Cell/*genetics
Lymphoma, B-Cell/*pathology
Proto-Oncogene Proteins c-bcl-2/*genetics
Proto-Oncogene Proteins c-bcl-6/*genetics
Proto-Oncogene Proteins c-myc/*genetics
Adult ; Aged ; Aged, 80 and over ; China ; Female ; Hepatitis B virus/pathogenicity ; Hepatitis B, Chronic/virology ; Humans ; Lymphoma, B-Cell/drug therapy ; Lymphoma, B-Cell/virology ; Male ; Middle Aged ; Neoplasm Grading ; Retrospective Studies ; Risk Factors ; Young Adult
Czasopismo naukowe
Tytuł :
How much, if anything, do we know about sperm chromosomes of Robertsonian translocation carriers?
Autorzy :
Wiland E; Institute of Human Genetics, Polish Academy of Sciences, ul. Strzeszynska 32, 60-479, Poznan, Poland.
Olszewska M; Institute of Human Genetics, Polish Academy of Sciences, ul. Strzeszynska 32, 60-479, Poznan, Poland.
Woźniak T; Institute of Human Genetics, Polish Academy of Sciences, ul. Strzeszynska 32, 60-479, Poznan, Poland.
Kurpisz M; Institute of Human Genetics, Polish Academy of Sciences, ul. Strzeszynska 32, 60-479, Poznan, Poland. .
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Źródło :
Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2020 Dec; Vol. 77 (23), pp. 4765-4785. Date of Electronic Publication: 2020 Jun 08.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Heterozygote*
Translocation, Genetic*
Chromosomes/*genetics
Spermatozoa/*metabolism
Chromosome Segregation/genetics ; Humans ; Male ; Meiosis/genetics
Czasopismo naukowe
Tytuł :
The prognostic value of additional copies of 1q21 in multiple myeloma depends on the primary genetic event.
Autorzy :
Locher M; Institute of Human Genetics, Medical University of Innsbruck, Innsbruck, Austria.
Steurer M; Department of Internal Medicine V, Medical University of Innsbruck, Innsbruck, Austria.
Jukic E; Institute of Human Genetics, Medical University of Innsbruck, Innsbruck, Austria.
Keller MA; Institute of Human Genetics, Medical University of Innsbruck, Innsbruck, Austria.
Fresser F; Institute of Human Genetics, Medical University of Innsbruck, Innsbruck, Austria.
Ruepp C; Department of Internal Medicine, St. Vinzenz Krankenhaus Betriebs GmbH, Zams, Austria.
Wöll E; Department of Internal Medicine, St. Vinzenz Krankenhaus Betriebs GmbH, Zams, Austria.
Verdorfer I; Institute of Human Genetics, Medical University of Innsbruck, Innsbruck, Austria.
Gastl G; Department of Internal Medicine V, Medical University of Innsbruck, Innsbruck, Austria.
Willenbacher W; Department of Internal Medicine V, Medical University of Innsbruck, Innsbruck, Austria.; ONCOTYROL - Center for Personalized Cancer Medicine, Innsbruck, Austria.
Weger R; ONCOTYROL - Center for Personalized Cancer Medicine, Innsbruck, Austria.
Nachbaur D; Department of Internal Medicine V, Medical University of Innsbruck, Innsbruck, Austria.
Wolf D; Department of Internal Medicine V, Medical University of Innsbruck, Innsbruck, Austria.; Medical Clinic 3, Oncology, Hematology, Immuno-Oncology and Rheumatology, University Hospital Bonn, Bonn, Germany.
Gunsilius E; Department of Internal Medicine V, Medical University of Innsbruck, Innsbruck, Austria.
Zschocke J; Institute of Human Genetics, Medical University of Innsbruck, Innsbruck, Austria.
Steiner N; Department of Internal Medicine V, Medical University of Innsbruck, Innsbruck, Austria.
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Źródło :
American journal of hematology [Am J Hematol] 2020 Dec; Vol. 95 (12), pp. 1562-1571. Date of Electronic Publication: 2020 Sep 19.
Typ publikacji :
Clinical Trial; Journal Article
MeSH Terms :
Genetic Loci*
Translocation, Genetic*
Chromosomes, Human, Pair 1/*genetics
Immunoglobulin Heavy Chains/*genetics
Multiple Myeloma/*genetics
Multiple Myeloma/*mortality
Neoplasm Proteins/*genetics
Adult ; Aged ; Aged, 80 and over ; CD56 Antigen/genetics ; Disease-Free Survival ; Female ; Humans ; Immunoglobulin G/genetics ; Male ; Middle Aged ; Multiple Myeloma/therapy ; Proto-Oncogene Proteins c-kit/genetics ; Survival Rate
Czasopismo naukowe
Tytuł :
Genotypic and Phenotypic Characteristics of Acute Promyelocytic Leukemia Translocation Variants.
Autorzy :
Mannan A; Betsi Cadwaladr University Health Board, Bangor, UK.
Muhsen IN; Department of Medicine, Houston Methodist Hospital, Houston, TX, USA. Electronic address: .
Barragán E; Department of Hematology, Hospital Universitari i Politecnic La Fe, Valencia, Spain; Department of Medicine, University of Valencia, Valencia, Spain; Centro de Investigación Biomédica en Red de Cáncer, Instituto Carlos III, Madrid, Spain.
Sanz MA; Department of Hematology, Hospital Universitari i Politecnic La Fe, Valencia, Spain; Department of Medicine, University of Valencia, Valencia, Spain; Centro de Investigación Biomédica en Red de Cáncer, Instituto Carlos III, Madrid, Spain.
Mohty M; Hôpital Saint-Antoine, Paris, France.
Hashmi SK; Oncology Center, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia; Department of Medicine, Mayo Clinic, Rochester, MN, USA.
Aljurf M; Oncology Center, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
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Źródło :
Hematology/oncology and stem cell therapy [Hematol Oncol Stem Cell Ther] 2020 Dec; Vol. 13 (4), pp. 189-201. Date of Electronic Publication: 2020 May 20.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Genotype*
Leukemia, Promyelocytic, Acute*/classification
Leukemia, Promyelocytic, Acute*/genetics
Leukemia, Promyelocytic, Acute*/metabolism
Neoplasm Proteins*/genetics
Neoplasm Proteins*/metabolism
Translocation, Genetic*
Humans
Czasopismo naukowe
Tytuł :
Dual role of G-quadruplex in translocation renal cell carcinoma: Exploring plausible Cancer therapeutic innovation.
Autorzy :
Neha; Centre for Genetic Disorders, Institute of Science, Banaras Hindu University, Varanasi 221005, India.
Das P; Centre for Genetic Disorders, Institute of Science, Banaras Hindu University, Varanasi 221005, India. Electronic address: .
Verma SP; Huntsman Cancer Institute, University of Utah, USA.
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Źródło :
Biochimica et biophysica acta. General subjects [Biochim Biophys Acta Gen Subj] 2020 Dec; Vol. 1864 (12), pp. 129719. Date of Electronic Publication: 2020 Aug 31.
Typ publikacji :
Journal Article; Review
MeSH Terms :
G-Quadruplexes*
Translocation, Genetic*
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors/*genetics
Carcinoma, Renal Cell/*genetics
Kidney Neoplasms/*genetics
Animals ; Carcinoma, Renal Cell/pathology ; Carcinoma, Renal Cell/therapy ; Humans ; Kidney Neoplasms/pathology ; Kidney Neoplasms/therapy ; Models, Molecular ; Oncogene Proteins, Fusion/genetics
Czasopismo naukowe
Tytuł :
A new case of myelodysplastic syndrome associated with t(3;3)(q21;q26) and inv(11)(p15q22).
Autorzy :
Monti V; Department of Pathology, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy.
Bagnoli F; Department of Clinical Oncology and Hematology, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy.; Department of Oncology and Onco-Hematology, University of Milan, Milan, Italy.
Bolli N; Department of Clinical Oncology and Hematology, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy.; Department of Oncology and Onco-Hematology, University of Milan, Milan, Italy.
Vittoria L; Department of Pathology, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy.
Stioui S; Cytogenetics and Medical Genetics Section, Humanitas Research Hospital, Milan, Italy.
Moiraghi ML; Department of Pathology, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy.
Pruneri G; Department of Pathology, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy.; Department of Oncology and Onco-Hematology, University of Milan, Milan, Italy.
Testi MA; Department of Pathology, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy.
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Źródło :
Tumori [Tumori] 2020 Dec; Vol. 106 (6), pp. NP18-NP22. Date of Electronic Publication: 2020 Aug 24.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Chromosome Inversion*
Translocation, Genetic*
Myelodysplastic Syndromes/*diagnosis
Myelodysplastic Syndromes/*genetics
Aged, 80 and over ; Biomarkers, Tumor ; Chromosomes, Human, Pair 11 ; Chromosomes, Human, Pair 3 ; Cytogenetic Analysis ; Humans ; In Situ Hybridization, Fluorescence
Czasopismo naukowe
Tytuł :
Chronic lymphocytic leukemia patients with IGH translocations are characterized by a distinct genetic landscape with prognostic implications.
Autorzy :
Pérez-Carretero C; Universidad de Salamanca, IBSAL, Centro de Investigación del Cáncer, IBMCC-CSIC, Salamanca, Spain.; Servicio de Hematología, Hospital Universitario de Salamanca, Salamanca, Spain.
Hernández-Sánchez M; Universidad de Salamanca, IBSAL, Centro de Investigación del Cáncer, IBMCC-CSIC, Salamanca, Spain.; Servicio de Hematología, Hospital Universitario de Salamanca, Salamanca, Spain.; Department of Medical Oncology, Dana Farber Cancer Institute, Boston, Massachusetts, USA.
González T; Universidad de Salamanca, IBSAL, Centro de Investigación del Cáncer, IBMCC-CSIC, Salamanca, Spain.; Servicio de Hematología, Hospital Universitario de Salamanca, Salamanca, Spain.
Quijada-Álamo M; Universidad de Salamanca, IBSAL, Centro de Investigación del Cáncer, IBMCC-CSIC, Salamanca, Spain.; Servicio de Hematología, Hospital Universitario de Salamanca, Salamanca, Spain.
Martín-Izquierdo M; Universidad de Salamanca, IBSAL, Centro de Investigación del Cáncer, IBMCC-CSIC, Salamanca, Spain.; Servicio de Hematología, Hospital Universitario de Salamanca, Salamanca, Spain.
Hernández-Sánchez JM; Universidad de Salamanca, IBSAL, Centro de Investigación del Cáncer, IBMCC-CSIC, Salamanca, Spain.; Servicio de Hematología, Hospital Universitario de Salamanca, Salamanca, Spain.
Vidal MJ; Servicio de Hematología, Hospital Universitario, León, Spain.
de Coca AG; Servicio de Hematología, Hospital Clínico, Valladolid, Spain.
Aguilar C; Servicio de Hematología, Complejo Hospitalario de Soria, Soria, Spain.
Vargas-Pabón M; Servicio de Hematología, Hospital Jarrio, Asturias, Spain.
Alonso S; Servicio de Hematología, Hospital Universitario Central de Asturias, Oviedo, Spain.
Sierra M; Servicio de Hematología, Hospital Virgen de la Concha, Zamora, Spain.
Rubio-Martínez A; Servicio de Hematología, Hospital Miguel Servet, Zaragoza, Spain.
Dávila J; Servicio de Hematología, Hospital Nuestra Señora de Sonsoles, Ávila, Spain.
Díaz-Valdés JR; Servicio de Hematología, Hospital General de Segovia, Segovia, Spain.
Queizán JA; Servicio de Hematología, Hospital General de Segovia, Segovia, Spain.
Hernández-Rivas JÁ; Servicio de Hematología, Hospital Universitario Infanta Leonor, Universidad Complutense, Madrid, Spain.
Benito R; Universidad de Salamanca, IBSAL, Centro de Investigación del Cáncer, IBMCC-CSIC, Salamanca, Spain.; Servicio de Hematología, Hospital Universitario de Salamanca, Salamanca, Spain.
Rodríguez-Vicente AE; Universidad de Salamanca, IBSAL, Centro de Investigación del Cáncer, IBMCC-CSIC, Salamanca, Spain.; Servicio de Hematología, Hospital Universitario de Salamanca, Salamanca, Spain.
Hernández-Rivas JM; Universidad de Salamanca, IBSAL, Centro de Investigación del Cáncer, IBMCC-CSIC, Salamanca, Spain.; Servicio de Hematología, Hospital Universitario de Salamanca, Salamanca, Spain.
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Źródło :
International journal of cancer [Int J Cancer] 2020 Nov 15; Vol. 147 (10), pp. 2780-2792. Date of Electronic Publication: 2020 Sep 04.
Typ publikacji :
Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Regulatory Networks*
Mutation*
Translocation, Genetic*
Immunoglobulin Heavy Chains/*genetics
Leukemia, Lymphocytic, Chronic, B-Cell/*genetics
Adult ; Aged ; Aged, 80 and over ; Chromosomes, Human, Pair 13/genetics ; Chromosomes, Human, Pair 14/genetics ; Female ; Genetic Predisposition to Disease ; High-Throughput Nucleotide Sequencing/methods ; Humans ; In Situ Hybridization, Fluorescence ; Male ; Middle Aged ; Prognosis ; Sequence Analysis, DNA
Czasopismo naukowe
Tytuł :
Polymerase δ promotes chromosomal rearrangements and imprecise double-strand break repair.
Autorzy :
Layer JV; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215.
Debaize L; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215.
Van Scoyk A; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215.
House NC; Department of Radiation Oncology, Dana-Farber Cancer Institute, Boston, MA 02215.
Brown AJ; School of Molecular Biosciences, Washington State University, Pullman, WA 99164.
Liu Y; The Koch Institute for Integrative Cancer Research at MIT, Massachusetts Institute of Technology, Cambridge, MA 02139.
Stevenson KE; Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA 02215.
Hemann M; The Koch Institute for Integrative Cancer Research at MIT, Massachusetts Institute of Technology, Cambridge, MA 02139.
Roberts SA; School of Molecular Biosciences, Washington State University, Pullman, WA 99164.
Price BD; Department of Radiation Oncology, Dana-Farber Cancer Institute, Boston, MA 02215.
Weinstock DM; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215; .; Cancer Biology Program, Broad Institute of MIT and Harvard University, Cambridge, MA 02142.; Biological and Biomedical Sciences Program, Harvard Medical School, Boston, MA 02215.
Day TA; Department of Biology, Northeastern University, Boston, MA 02115 .
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Nov 03; Vol. 117 (44), pp. 27566-27577. Date of Electronic Publication: 2020 Oct 19.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
DNA End-Joining Repair*
Translocation, Genetic*
DNA Polymerase III/*metabolism
DNA Breaks, Double-Stranded ; DNA Polymerase III/genetics ; Gene Knockdown Techniques ; HEK293 Cells ; HeLa Cells ; Humans ; RNA, Small Interfering/metabolism
Czasopismo naukowe
Tytuł :
Acute myeloid leukemia with 11q23 rearrangements: A study of therapy-related disease and therapeutic outcomes.
Autorzy :
Menghrajani K; Memorial Sloan Kettering Cancer Center, USA. Electronic address: .
Zhang Y; Memorial Sloan Kettering Cancer Center, USA.
Famulare C; Memorial Sloan Kettering Cancer Center, USA.
Devlin SM; Memorial Sloan Kettering Cancer Center, USA.
Tallman MS; Memorial Sloan Kettering Cancer Center, USA; Weill-Cornell Medical College, USA.
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Źródło :
Leukemia research [Leuk Res] 2020 Nov; Vol. 98, pp. 106453. Date of Electronic Publication: 2020 Sep 16.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Breast Neoplasms*/drug therapy
Breast Neoplasms*/genetics
Breast Neoplasms*/metabolism
Breast Neoplasms*/pathology
Chromosomes, Human, Pair 11*/genetics
Chromosomes, Human, Pair 11*/metabolism
Leukemia, Myeloid, Acute*/drug therapy
Leukemia, Myeloid, Acute*/genetics
Leukemia, Myeloid, Acute*/metabolism
Leukemia, Myeloid, Acute*/pathology
Neoplasms, Second Primary*/drug therapy
Neoplasms, Second Primary*/genetics
Neoplasms, Second Primary*/metabolism
Neoplasms, Second Primary*/pathology
Translocation, Genetic*
Anthracyclines/*administration & dosage
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Chromosomes, Human, Pair 19/genetics ; Chromosomes, Human, Pair 19/metabolism ; Chromosomes, Human, Pair 9/genetics ; Chromosomes, Human, Pair 9/metabolism ; Female ; Humans ; Male ; Middle Aged
Czasopismo naukowe
Tytuł :
TYRO3 Truncation Resulting From a t(10;15)(p11;q15) Chromosomal Translocation in Pediatric Acute Myeloid Leukemia.
Autorzy :
Brunetti M; Section for Cancer Cytogenetics, Institute for Cancer Genetics and Informatics, The Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway.
Zeller B; Division of Pediatric and Adolescent Medicine, Oslo University Hospital Rikshospitalet, Oslo, Norway.
Tierens A; Laboratory Medicine Program, Department of Haematopathology, University Health Network, Toronto, ON, Canada.
Heim S; Section for Cancer Cytogenetics, Institute for Cancer Genetics and Informatics, The Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway.; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.
Micci F; Section for Cancer Cytogenetics, Institute for Cancer Genetics and Informatics, The Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway.
Panagopoulos I; Section for Cancer Cytogenetics, Institute for Cancer Genetics and Informatics, The Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway .
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Źródło :
Anticancer research [Anticancer Res] 2020 Nov; Vol. 40 (11), pp. 6115-6121.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Translocation, Genetic*
Chromosomes, Human, Pair 10/*genetics
Chromosomes, Human, Pair 15/*genetics
Leukemia, Myeloid, Acute/*genetics
Receptor Protein-Tyrosine Kinases/*genetics
Base Sequence ; Child ; Humans ; Male
Czasopismo naukowe

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