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    Wyświetlanie 1-15 z 15
    Tytuł:
    An exploratory study investigating biomarkers associated with autoimmune pulmonary alveolar proteinosis (aPAP).
    Autorzy:
    Campo I; UOS trasnplant center and Pneumology Unit, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
    Meloni F; UOS trasnplant center and Pneumology Unit, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy. .; Department of Internal Medicine, University of Pavia, Pavia, Italy. .
    Gahlemann M; Boehringer Ingelheim (Schweiz) GmbH, Basel, Switzerland.
    Sauter W; Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach an der Riss, Germany.
    Ittrich C; Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach an der Riss, Germany.
    Schoelch C; Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach an der Riss, Germany.
    Trapnell BC; Translational Pulmonary Science Center, Cincinnati Children's Hospital, Cincinnati, OH, USA.
    Gupta A; Boehringer Ingelheim International GmbH, Biberach an der Riss, Germany.
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    Źródło:
    Scientific reports [Sci Rep] 2022 May 24; Vol. 12 (1), pp. 8708. Date of Electronic Publication: 2022 May 24.
    Typ publikacji:
    Journal Article; Observational Study; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Asthma*/complications
    Asthma*/diagnosis
    Autoimmune Diseases*
    Pulmonary Alveolar Proteinosis*/diagnosis
    Pulmonary Disease, Chronic Obstructive*/complications
    Autoantibodies ; Biomarkers ; Granulocyte-Macrophage Colony-Stimulating Factor ; Humans ; Prospective Studies
    SCR Disease Name:
    Pulmonary Alveolar Proteinosis, Acquired
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Prevalence and healthcare burden of pulmonary alveolar proteinosis.
    Autorzy:
    McCarthy C; Translational Pulmonary Science Center, Children's Hospital Medical Center, Cincinnati, OH, USA.; Division of Pulmonary, Critical Care, and Sleep Medicine, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
    Avetisyan R; Sanofi, Cambridge, MA, USA.
    Carey BC; Translational Pulmonary Science Center, Children's Hospital Medical Center, Cincinnati, OH, USA.; PAP Foundation, Denver, CO, USA.
    Chalk C; Translational Pulmonary Science Center, Children's Hospital Medical Center, Cincinnati, OH, USA.
    Trapnell BC; Translational Pulmonary Science Center, Children's Hospital Medical Center, Cincinnati, OH, USA. Bruce.Trapnell@cchmc.org.; Division of Pulmonary, Critical Care, and Sleep Medicine, University of Cincinnati College of Medicine, Cincinnati, OH, USA. Bruce.Trapnell@cchmc.org.; PAP Foundation, Denver, CO, USA. Bruce.Trapnell@cchmc.org.; Division of Pulmonary Biology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH, 45229-3039, USA. Bruce.Trapnell@cchmc.org.
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    Źródło:
    Orphanet journal of rare diseases [Orphanet J Rare Dis] 2018 Jul 31; Vol. 13 (1), pp. 129. Date of Electronic Publication: 2018 Jul 31.
    Typ publikacji:
    Letter; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Pulmonary Alveolar Proteinosis/*economics
    Pulmonary Alveolar Proteinosis/*epidemiology
    Adolescent ; Adult ; Aged ; Autoantibodies/metabolism ; Female ; Granulocyte-Macrophage Colony-Stimulating Factor/metabolism ; Humans ; Male ; Middle Aged ; Prevalence ; Pulmonary Alveolar Proteinosis/immunology ; Pulmonary Alveolar Proteinosis/metabolism ; Retrospective Studies ; Young Adult
    Raport
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Whole lung lavage therapy for pulmonary alveolar proteinosis: a global survey of current practices and procedures.
    Autorzy:
    Campo I; Pneumology Unit, Fondazione IRCCS Policlinico San Matteo and University of Pavia, Pavia, Italy. .; Laboratorio di Biochimica e Genetica, S.C. Pneumologia, Fondazione IRCCS Policlinico San Matteo, via Taramelli 5, 27100, Pavia, Italy. .
    Luisetti M; Pneumology Unit, Fondazione IRCCS Policlinico San Matteo and University of Pavia, Pavia, Italy.
    Griese M; Kinderklinik und Kinderpoliklinik im Dr. von Haunerschen Kinderspital, University of Munich, Munich, Germany.
    Trapnell BC; Translational Pulmonary Science Centre, Cincinnati Children's Hospital, Cincinnati, OH, USA.
    Bonella F; Interstitial and Rare Lung Disease Unit, Ruhrlandklinik University Hospital, University of Duisburg-Essen, Essen, Germany.
    Grutters J; Centre of Interstitial Lung Diseases, St. Antonius Hospital Nieuwegein, Nieuwegein, The Netherlands.
    Nakata K; Niigata University Medical and Dental School, Niigata, Japan.
    Van Moorsel CH; Centre of Interstitial Lung Diseases, St. Antonius Hospital Nieuwegein, Nieuwegein, The Netherlands.
    Costabel U; Interstitial and Rare Lung Disease Unit, Ruhrlandklinik University Hospital, University of Duisburg-Essen, Essen, Germany.
    Cottin V; National Reference Centre for Rare Pulmonary Disease, Hopital Louis Pradel, Lyon, France.
    Ichiwata T; Tokyo Medical University Hachioji Medical Center, Tokyo, Japan.
    Inoue Y; Department of Diffuse Lung Diseases and Respiratory Failure, Clinical Research Centre, National Hospital Organization Kinki-Chuo Chest Medical Centre, Osaka, Japan.
    Braschi A; Department of Anesthesiology and Intensive Care, Fondazione IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy.
    Bonizzoni G; Pneumology Unit, Fondazione IRCCS Policlinico San Matteo and University of Pavia, Pavia, Italy.
    Iotti GA; Department of Anesthesiology and Intensive Care, Fondazione IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy.
    Tinelli C; Clinical Epidemiology and Biometric Unit, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
    Rodi G; Department of Anesthesiology and Intensive Care, Fondazione IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy.
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    Corporate Authors:
    WLL International Study Group
    Źródło:
    Orphanet journal of rare diseases [Orphanet J Rare Dis] 2016 Aug 31; Vol. 11 (1), pp. 115. Date of Electronic Publication: 2016 Aug 31.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Bronchoalveolar Lavage/*methods
    Pulmonary Alveolar Proteinosis/*therapy
    Bronchoalveolar Lavage Fluid ; Female ; Humans ; Lung/metabolism ; Lung/pathology ; Lung Diseases, Interstitial/metabolism ; Lung Diseases, Interstitial/therapy ; Male ; Pulmonary Alveolar Proteinosis/metabolism ; Surveys and Questionnaires
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Epidermal growth factor receptor signalling regulates granulocyte-macrophage colony-stimulating factor production by airway epithelial cells and established allergic airway disease.
    Autorzy:
    Acciani TH; Division of Pulmonary Biology, Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
    Suzuki T; Division of Pulmonary Biology, Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.; Translational Pulmonary Science Center, Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
    Trapnell BC; Division of Pulmonary Biology, Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.; Translational Pulmonary Science Center, Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Division of Pulmonary Medicine, Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Division of Pulmonary, Critical Care and Sleep Medicine, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
    Le Cras TD; Division of Pulmonary Biology, Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
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    Źródło:
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology [Clin Exp Allergy] 2016 Feb; Vol. 46 (2), pp. 317-28.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural
    MeSH Terms:
    Asthma/*immunology
    ErbB Receptors/*immunology
    Granulocyte-Macrophage Colony-Stimulating Factor/*biosynthesis
    Respiratory Mucosa/*immunology
    Signal Transduction/*immunology
    Animals ; Asthma/metabolism ; Blotting, Western ; Cells, Cultured ; Enzyme-Linked Immunosorbent Assay ; ErbB Receptors/metabolism ; Female ; Humans ; Interleukin-17/immunology ; Mice ; Pyroglyphidae/immunology ; Respiratory Hypersensitivity/immunology ; Respiratory Hypersensitivity/metabolism ; Respiratory Mucosa/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Pulmonary macrophage transplantation therapy.
    Autorzy:
    Suzuki T; Division of Pulmonary Biology, Perinatal Institute, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, Ohio 45229, USA.
    Arumugam P; Division of Experimental Hematology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, Ohio 45229, USA.
    Sakagami T; Division of Pulmonary Biology, Perinatal Institute, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, Ohio 45229, USA.
    Lachmann N; RG Reprograming and Gene Therapy, Institute of Experimental Hematology, Hannover Medical School, Carl Neuberg-Str. 1, 30625 Hannover, Germany.
    Chalk C; Division of Pulmonary Biology, Perinatal Institute, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, Ohio 45229, USA.
    Sallese A; Division of Pulmonary Biology, Perinatal Institute, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, Ohio 45229, USA.
    Abe S; Division of Pulmonary Biology, Perinatal Institute, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, Ohio 45229, USA.
    Trapnell C; 1] Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, Massachusetts 02138, USA [2] Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts 02138, USA.
    Carey B; Division of Pulmonary Biology, Perinatal Institute, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, Ohio 45229, USA.
    Moritz T; RG Reprograming and Gene Therapy, Institute of Experimental Hematology, Hannover Medical School, Carl Neuberg-Str. 1, 30625 Hannover, Germany.
    Malik P; Division of Experimental Hematology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, Ohio 45229, USA.
    Lutzko C; Division of Experimental Hematology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, Ohio 45229, USA.
    Wood RE; Division of Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, Ohio 45229, USA.
    Trapnell BC; 1] Division of Pulmonary Biology, Perinatal Institute, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, Ohio 45229, USA [2] Division of Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, Ohio 45229, USA [3] Division of Pulmonary, Critical Care, and Sleep Medicine, University of Cincinnati Medical Center, 3333 Burnet Avenue, Cincinnati, Ohio 45229, USA.
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    Źródło:
    Nature [Nature] 2014 Oct 23; Vol. 514 (7523), pp. 450-4. Date of Electronic Publication: 2014 Oct 01.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Cell Transplantation*
    Genetic Therapy*
    Cytokine Receptor Common beta Subunit/*genetics
    Lung/*cytology
    Macrophages, Alveolar/*metabolism
    Macrophages, Alveolar/*transplantation
    Pulmonary Alveolar Proteinosis/*therapy
    Animals ; Cell Separation ; Cytokine Receptor Common beta Subunit/deficiency ; Female ; Lung/metabolism ; Lung/pathology ; Male ; Mice ; Oligonucleotide Array Sequence Analysis ; Phenotype ; Pulmonary Alveolar Proteinosis/genetics ; Pulmonary Alveolar Proteinosis/pathology ; Time Factors
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Paediatric Crohn disease patients with stricturing behaviour exhibit ileal granulocyte-macrophage colony-stimulating factor (GM-CSF) autoantibody production and reduced neutrophil bacterial killing and GM-CSF bioactivity.
    Autorzy:
    Jurickova I; Department of Pediatrics Gastroenterology, Hepatology, and Nutrition, Cincinnati Children's Hospital Medical Center and the University of Cincinnati College of Medicine, Cincinnati, OH, USA.
    Collins MH
    Chalk C
    Seese A
    Bezold R
    Lake K
    von Allmen D
    Frischer JS
    Falcone RA
    Trapnell BC
    Denson LA
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    Źródło:
    Clinical and experimental immunology [Clin Exp Immunol] 2013 Jun; Vol. 172 (3), pp. 455-65.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Autoantibodies/*biosynthesis
    Crohn Disease/*immunology
    Granulocyte-Macrophage Colony-Stimulating Factor/*immunology
    Neutrophils/*immunology
    Adolescent ; Antibodies, Neutralizing/biosynthesis ; Blood Bactericidal Activity ; Case-Control Studies ; Child ; Child, Preschool ; Constriction, Pathologic ; Crohn Disease/metabolism ; Crohn Disease/pathology ; Female ; Granulocyte-Macrophage Colony-Stimulating Factor/administration & dosage ; Granulocyte-Macrophage Colony-Stimulating Factor/metabolism ; Humans ; Ileum/immunology ; Ileum/metabolism ; Ileum/pathology ; Infant ; Male ; Neutrophils/metabolism ; STAT5 Transcription Factor/metabolism ; Staphylococcus aureus/immunology ; Young Adult
    SCR Disease Name:
    Pediatric Crohn's disease
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Assessment and management of pulmonary alveolar proteinosis in a reference center.
    Autorzy:
    Campo I; Respiratory Disease Unit, Fondazione IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy.
    Mariani F
    Rodi G
    Paracchini E
    Tsana E
    Piloni D
    Nobili I
    Kadija Z
    Corsico A
    Cerveri I
    Chalk C
    Trapnell BC
    Braschi A
    Tinelli C
    Luisetti M
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    Źródło:
    Orphanet journal of rare diseases [Orphanet J Rare Dis] 2013 Mar 13; Vol. 8, pp. 40. Date of Electronic Publication: 2013 Mar 13.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Pulmonary Alveolar Proteinosis/*diagnosis
    Pulmonary Alveolar Proteinosis/*therapy
    Adult ; Female ; Humans ; Male ; Middle Aged ; Occupational Exposure ; Pulmonary Alveolar Proteinosis/physiopathology ; Pulmonary Surfactants ; Reference Values
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Evaluation of full-length, cleaved and nitrosylated serum surfactant protein D as biomarkers for COPD.
    Autorzy:
    Duvoix A; Department of Medicine, University of Cambridge, Cambridge Institute for Medical Research, Wellcome Trust/MRC Building, Cambridge, UK.
    Miranda E
    Perez J
    Sorensen GL
    Holmskov U
    Trapnell BC
    Madsen J
    Clark HW
    Edwards LD
    Miller BE
    Tal-Singer RM
    Lomas DA
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    Źródło:
    COPD [COPD] 2011 Apr; Vol. 8 (2), pp. 79-95.
    Typ publikacji:
    Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Antibodies, Monoclonal/*immunology
    Pulmonary Disease, Chronic Obstructive/*blood
    Pulmonary Surfactant-Associated Protein D/*blood
    Pulmonary Surfactant-Associated Protein D/*immunology
    Adult ; Aged ; Animals ; Biomarkers/blood ; Disease Progression ; Forced Expiratory Volume ; Humans ; Mice ; Middle Aged ; Prospective Studies ; Pulmonary Disease, Chronic Obstructive/physiopathology ; Statistics, Nonparametric ; Vital Capacity
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
      Wyświetlanie 1-15 z 15

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