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Tytuł :
High baseline soluble urokinase plasminogen activator receptor (suPAR) serum levels indicate adverse outcome after resection of pancreatic adenocarcinoma.
Autorzy :
Loosen SH; Department of Medicine III, Hepatology and Hepatobiliary Oncology, Pauwelsstrasse, Aachen, Germany.
Tacke F; Department of Medicine III, Hepatology and Hepatobiliary Oncology, Pauwelsstrasse, Aachen, Germany.
Püthe N; Division of Gastroenterology, Hepatology and Hepatobiliary Oncology, Pauwelsstrasse, Aachen, Germany.
Binneboesel M; Department of Visceral and Transplantation Surgery, University Hospital RWTH Aachen, Pauwelsstrasse, Aachen, Germany.; Department of General and Visceral Surgery, Klinikum Bielefeld, Bielefeld, Germany.
Wiltberger G; Department of Visceral and Transplantation Surgery, University Hospital RWTH Aachen, Pauwelsstrasse, Aachen, Germany.
Alizai PH; Department of Visceral and Transplantation Surgery, University Hospital RWTH Aachen, Pauwelsstrasse, Aachen, Germany.
Kather JN; Department of Medicine III, Hepatology and Hepatobiliary Oncology, Pauwelsstrasse, Aachen, Germany.
Paffenholz P; Department of Urology, University Hospital Cologne, Kerpener Straße, Germany.
Ritz T; Institute of Pathology, University Hospital RWTH Aachen, Pauwelsstrasse, Aachen, Germany.; Institute of Pathology, University Hospital Heidelberg, Im Neuenheimer Feld, Heidelberg, Germany.
Koch A; Department of Medicine III, Hepatology and Hepatobiliary Oncology, Pauwelsstrasse, Aachen, Germany.
Bergmann F; Institute of Pathology, University Hospital Heidelberg, Im Neuenheimer Feld, Heidelberg, Germany.
Trautwein C; Department of Medicine III, Hepatology and Hepatobiliary Oncology, Pauwelsstrasse, Aachen, Germany.
Longerich T; Institute of Pathology, University Hospital RWTH Aachen, Pauwelsstrasse, Aachen, Germany.; Institute of Pathology, University Hospital Heidelberg, Im Neuenheimer Feld, Heidelberg, Germany.
Roderburg C; Department of Medicine III, Hepatology and Hepatobiliary Oncology, Pauwelsstrasse, Aachen, Germany.
Neumann UP; Department of Visceral and Transplantation Surgery, University Hospital RWTH Aachen, Pauwelsstrasse, Aachen, Germany.
Luedde T; Department of Medicine III, Hepatology and Hepatobiliary Oncology, Pauwelsstrasse, Aachen, Germany.; Division of Gastroenterology, Hepatology and Hepatobiliary Oncology, Pauwelsstrasse, Aachen, Germany.
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Źródło :
Carcinogenesis [Carcinogenesis] 2019 Aug 22; Vol. 40 (8), pp. 947-955.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Adenocarcinoma/*blood
Inflammation/*blood
Pancreatic Neoplasms/*blood
Receptors, Urokinase Plasminogen Activator/*blood
Adenocarcinoma/genetics ; Adenocarcinoma/pathology ; Adenocarcinoma/surgery ; Adult ; Aged ; Aged, 80 and over ; Biomarkers, Tumor/blood ; Disease-Free Survival ; Female ; Gene Expression Regulation, Neoplastic/genetics ; Humans ; Inflammation/genetics ; Inflammation/pathology ; Male ; Middle Aged ; Pancreatectomy/adverse effects ; Pancreatic Neoplasms/genetics ; Pancreatic Neoplasms/pathology ; Pancreatic Neoplasms/surgery ; Prognosis ; Proportional Hazards Models
Czasopismo naukowe
Tytuł :
Myeloid cells require gp130 signaling for protective anti-inflammatory functions during sepsis.
Autorzy :
Sackett SD; Department of Internal Medicine III, University Hospital Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen, Aachen, Germany.; Department of Surgery, Division of Transplantation, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Otto T; Department of Internal Medicine III, University Hospital Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen, Aachen, Germany.
Mohs A; Department of Internal Medicine III, University Hospital Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen, Aachen, Germany.
Sander LE; Department of Internal Medicine III, University Hospital Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen, Aachen, Germany.; Department of Infectious Diseases and Pulmonary Medicine, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, Berlin, Germany.; German Center for Lung Research (DZL), Berlin, Germany.
Strauch S; Department of Internal Medicine III, University Hospital Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen, Aachen, Germany.
Streetz KL; Department of Internal Medicine III, University Hospital Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen, Aachen, Germany.
Kroy DC; Department of Internal Medicine III, University Hospital Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen, Aachen, Germany.
Trautwein C; Department of Internal Medicine III, University Hospital Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen, Aachen, Germany.
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Źródło :
FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2019 May; Vol. 33 (5), pp. 6035-6044. Date of Electronic Publication: 2019 Feb 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cytokine Receptor gp130/*metabolism
Inflammation/*metabolism
Macrophages/*metabolism
Myeloid Cells/*metabolism
Sepsis/*metabolism
Animals ; Cytokines/metabolism ; Hematopoietic Stem Cells/cytology ; Homeostasis ; Humans ; Immune System ; Interleukin-10/metabolism ; Macrophage Activation ; Mice ; Mice, Knockout ; Phenotype ; Recombinant Proteins/metabolism ; Signal Transduction
Czasopismo naukowe
Tytuł :
CXCR6 protects from inflammation and fibrosis in NEMO mice.
Autorzy :
Liepelt A; Department of Medicine III, RWTH-University Hospital Aachen, Pauwelsstr. 30, 52074 Aachen, Germany.
Wehr A; Department of Medicine III, RWTH-University Hospital Aachen, Pauwelsstr. 30, 52074 Aachen, Germany.
Kohlhepp M; Department of Medicine III, RWTH-University Hospital Aachen, Pauwelsstr. 30, 52074 Aachen, Germany.
Mossanen JC; Department of Medicine III, RWTH-University Hospital Aachen, Pauwelsstr. 30, 52074 Aachen, Germany; Department of Intensive and Intermediate Care, RWTH-University Hospital Aachen, Pauwelsstr. 30, 52074 Aachen, Germany.
Kreggenwinkel K; Department of Medicine III, RWTH-University Hospital Aachen, Pauwelsstr. 30, 52074 Aachen, Germany.
Denecke B; Chip Facility, IZKF Aachen, University Hospital, RWTH Aachen University, Pauwelsstr. 30, 52074 Aachen, Germany.
Costa IG; IZKF Computational Biology Research Group, University Hospital, Pauwelsstraße 19, RWTH Aachen University, 52074 Aachen, Germany.
Luedde T; Department of Medicine III, RWTH-University Hospital Aachen, Pauwelsstr. 30, 52074 Aachen, Germany.
Trautwein C; Department of Medicine III, RWTH-University Hospital Aachen, Pauwelsstr. 30, 52074 Aachen, Germany.
Tacke F; Department of Medicine III, RWTH-University Hospital Aachen, Pauwelsstr. 30, 52074 Aachen, Germany. Electronic address: .
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Źródło :
Biochimica et biophysica acta. Molecular basis of disease [Biochim Biophys Acta Mol Basis Dis] 2019 Feb 01; Vol. 1865 (2), pp. 391-402. Date of Electronic Publication: 2018 Nov 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Fatty Liver/*metabolism
Fatty Liver/*prevention & control
Inflammation/*metabolism
Inflammation/*prevention & control
Intracellular Signaling Peptides and Proteins/*deficiency
Receptors, CXCR6/*metabolism
Adoptive Transfer ; Animals ; Apoptosis ; Cells, Cultured ; Cytochrome P-450 CYP4A/metabolism ; Fatty Liver/pathology ; Hepatocytes/metabolism ; Hepatocytes/pathology ; Inflammation/pathology ; Intracellular Signaling Peptides and Proteins/metabolism ; Liver/injuries ; Liver/metabolism ; Liver/pathology ; Male ; Mice, Knockout ; Receptors, CXCR6/deficiency ; Stress, Physiological ; Tumor Necrosis Factor-alpha/adverse effects ; Up-Regulation
Czasopismo naukowe
Tytuł :
Intestinal Microbiota Protects against MCD Diet-Induced Steatohepatitis.
Autorzy :
Schneider KM; Department of Internal Medicine III, University Hospital RWTH Aachen, 52074 Aachen, Germany. .
Mohs A; Department of Internal Medicine III, University Hospital RWTH Aachen, 52074 Aachen, Germany. .
Kilic K; Department of Internal Medicine III, University Hospital RWTH Aachen, 52074 Aachen, Germany. .
Candels LS; Department of Internal Medicine III, University Hospital RWTH Aachen, 52074 Aachen, Germany. .
Elfers C; Department of Internal Medicine III, University Hospital RWTH Aachen, 52074 Aachen, Germany. .
Bennek E; Department of Internal Medicine III, University Hospital RWTH Aachen, 52074 Aachen, Germany. .
Schneider LB; Department of Internal Medicine III, University Hospital RWTH Aachen, 52074 Aachen, Germany. .
Heymann F; Department of Internal Medicine III, University Hospital RWTH Aachen, 52074 Aachen, Germany. .
Gassler N; Department of Pathology, Klinikum Braunschweig, 38118 Braunschweig, Germany. .
Penders J; Department of Medical Microbiology, School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Center, 6200 MD Maastricht, The Netherlands. .
Trautwein C; Department of Internal Medicine III, University Hospital RWTH Aachen, 52074 Aachen, Germany. .
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2019 Jan 14; Vol. 20 (2). Date of Electronic Publication: 2019 Jan 14.
Typ publikacji :
Journal Article
MeSH Terms :
Gastrointestinal Microbiome/*drug effects
Inflammation/*genetics
Liver Cirrhosis/*metabolism
Non-alcoholic Fatty Liver Disease/*metabolism
Animals ; Choline/adverse effects ; Choline/metabolism ; Choline Deficiency/metabolism ; Diet, High-Fat/adverse effects ; Disease Models, Animal ; Gastrointestinal Microbiome/genetics ; Genetic Variation/genetics ; Humans ; Inflammation/metabolism ; Inflammation/microbiology ; Liver Cirrhosis/etiology ; Liver Cirrhosis/pathology ; Male ; Methionine/adverse effects ; Methionine/deficiency ; Methionine/metabolism ; Mice ; Non-alcoholic Fatty Liver Disease/etiology ; Non-alcoholic Fatty Liver Disease/pathology
Czasopismo naukowe
Tytuł :
Immunomodulatory Therapy of Inflammatory Liver Disease Using Selectin-Binding Glycopolymers.
Autorzy :
Bartneck M
Schlößer CT
Barz M; Institute for Organic Chemistry, Johannes Gutenberg-University Mainz , 55122 Mainz, Germany.
Zentel R; Institute for Organic Chemistry, Johannes Gutenberg-University Mainz , 55122 Mainz, Germany.
Trautwein C
Lammers T
Tacke F
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Źródło :
ACS nano [ACS Nano] 2017 Oct 24; Vol. 11 (10), pp. 9689-9700. Date of Electronic Publication: 2017 Aug 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Immunomodulation*
Inflammation/*drug therapy
Liver Diseases/*drug therapy
Polysaccharides/*therapeutic use
Selectins/*therapeutic use
Animals ; Binding Sites ; Cells, Cultured ; Cytokines/blood ; Disease Models, Animal ; Dynamic Light Scattering ; Humans ; Liver Diseases/metabolism ; Mice ; Mice, Inbred C57BL
Czasopismo naukowe
Tytuł :
TRAIL receptor deletion in mice suppresses the inflammation of nutrient excess.
Autorzy :
Idrissova L; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN 55905, United States.
Malhi H; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN 55905, United States. Electronic address: .
Werneburg NW; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN 55905, United States.
LeBrasseur NK; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN 55905, United States.
Bronk SF; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN 55905, United States.
Fingas C; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN 55905, United States.
Tchkonia T; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN 55905, United States.
Pirtskhalava T; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN 55905, United States.
White TA; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN 55905, United States.
Stout MB; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN 55905, United States.
Hirsova P; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN 55905, United States.
Krishnan A; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN 55905, United States.
Liedtke C; Department of Medicine III, University Hospital, Aachen, Germany.
Trautwein C; Department of Medicine III, University Hospital, Aachen, Germany.
Finnberg N; Penn State Hershey Cancer Institute, Hershey, PA 17033, United States.
El-Deiry WS; Penn State Hershey Cancer Institute, Hershey, PA 17033, United States.
Kirkland JL; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN 55905, United States.
Gores GJ; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN 55905, United States. Electronic address: .
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Źródło :
Journal of hepatology [J Hepatol] 2015 May; Vol. 62 (5), pp. 1156-63. Date of Electronic Publication: 2014 Nov 28.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Adipose Tissue*/metabolism
Adipose Tissue*/pathology
Inflammation*/etiology
Inflammation*/metabolism
Inflammation*/pathology
Liver*/metabolism
Liver*/pathology
Macrophages*/metabolism
Macrophages*/pathology
Obesity*/complications
Obesity*/metabolism
Obesity*/pathology
Receptors, TNF-Related Apoptosis-Inducing Ligand*/genetics
Receptors, TNF-Related Apoptosis-Inducing Ligand*/metabolism
Animals ; Chemotaxis ; Diet, High-Fat/methods ; Disease Models, Animal ; Macrophage Activation ; Mice ; Mice, Knockout ; Signal Transduction
Czasopismo naukowe
Tytuł :
Fluorescent cell-traceable dexamethasone-loaded liposomes for the treatment of inflammatory liver diseases.
Autorzy :
Bartneck M; Department of Medicine III, Medical Faculty, RWTH Aachen, Pauwelsstr. 30, 52074 Aachen, Germany.
Scheyda KM; Department of Medicine III, Medical Faculty, RWTH Aachen, Pauwelsstr. 30, 52074 Aachen, Germany.
Warzecha KT; Department of Medicine III, Medical Faculty, RWTH Aachen, Pauwelsstr. 30, 52074 Aachen, Germany.
Rizzo LY; Department of Experimental Molecular Imaging (ExMI), Helmholtz Institute for Biomedical Engineering, Medical Faculty, RWTH Aachen, Pauwelsstr. 30, 52074 Aachen, Germany.
Hittatiya K; Institute of Pathology, University Bonn, Sigmund-Freud-Str. 25, 53127 Bonn, Germany.
Luedde T; Department of Medicine III, Medical Faculty, RWTH Aachen, Pauwelsstr. 30, 52074 Aachen, Germany.
Storm G; Department of Controlled Drug Delivery, MIRA Institute for Biomedical Technology and Technical Medicine, University of Twente, PO Box 217, 7500 AE Enschede, The Netherlands; Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences (UPIS), Universiteitsweg 99, 3584 CG Utrecht, The Netherlands.
Trautwein C; Department of Medicine III, Medical Faculty, RWTH Aachen, Pauwelsstr. 30, 52074 Aachen, Germany.
Lammers T; Department of Experimental Molecular Imaging (ExMI), Helmholtz Institute for Biomedical Engineering, Medical Faculty, RWTH Aachen, Pauwelsstr. 30, 52074 Aachen, Germany; Department of Controlled Drug Delivery, MIRA Institute for Biomedical Technology and Technical Medicine, University of Twente, PO Box 217, 7500 AE Enschede, The Netherlands; Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences (UPIS), Universiteitsweg 99, 3584 CG Utrecht, The Netherlands.
Tacke F; Department of Medicine III, Medical Faculty, RWTH Aachen, Pauwelsstr. 30, 52074 Aachen, Germany. Electronic address: .
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Źródło :
Biomaterials [Biomaterials] 2015 Jan; Vol. 37, pp. 367-82. Date of Electronic Publication: 2014 Oct 26.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Dexamethasone/*therapeutic use
Inflammation/*drug therapy
Liver Diseases/*drug therapy
Animals ; Cell Death/drug effects ; Cell Survival/drug effects ; Dexamethasone/administration & dosage ; Dexamethasone/pharmacology ; Fluorescence ; Hepatitis/drug therapy ; Hepatitis/pathology ; Immunomodulation/drug effects ; Immunosuppression ; Inflammation/pathology ; Liposomes ; Liver/drug effects ; Liver/immunology ; Liver/pathology ; Liver Cirrhosis/drug therapy ; Liver Cirrhosis/pathology ; Liver Diseases/complications ; Liver Diseases/pathology ; Mice, Inbred C57BL ; Organ Specificity/drug effects ; T-Lymphocytes/drug effects ; Tissue Distribution/drug effects
Czasopismo naukowe
Tytuł :
Hepatocyte specific deletion of c-Met leads to the development of severe non-alcoholic steatohepatitis in mice.
Autorzy :
Kroy DC; Department of Medicine 3, RWTH Aachen University Hospital, 52074 Aachen, Germany. Electronic address: .
Schumacher F; Department of Medicine 3, RWTH Aachen University Hospital, 52074 Aachen, Germany.
Ramadori P; Department of Medicine 3, RWTH Aachen University Hospital, 52074 Aachen, Germany.
Hatting M; Department of Medicine 3, RWTH Aachen University Hospital, 52074 Aachen, Germany.
Bergheim I; Institute of Nutrition, Friedrich-Schiller-University, Jena, 07743 Jena, Germany.
Gassler N; Institute of Pathology, RWTH Aachen University Hospital, 52074 Aachen, Germany.
Boekschoten MV; Wageningen University, Nutrition, Metabolism and Genomics Group, Division of Human Nutrition, Wageningen, The Netherlands.
Müller M; Wageningen University, Nutrition, Metabolism and Genomics Group, Division of Human Nutrition, Wageningen, The Netherlands.
Streetz KL; Department of Medicine 3, RWTH Aachen University Hospital, 52074 Aachen, Germany.
Trautwein C; Department of Medicine 3, RWTH Aachen University Hospital, 52074 Aachen, Germany.
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Źródło :
Journal of hepatology [J Hepatol] 2014 Oct; Vol. 61 (4), pp. 883-90. Date of Electronic Publication: 2014 May 15.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Apoptosis*
Choline Deficiency*/metabolism
Diet*/adverse effects
Diet*/methods
Liver Cirrhosis*/etiology
Liver Cirrhosis*/metabolism
Liver Cirrhosis*/prevention & control
Methionine*/deficiency
Methionine*/metabolism
Non-alcoholic Fatty Liver Disease*/complications
Non-alcoholic Fatty Liver Disease*/metabolism
Non-alcoholic Fatty Liver Disease*/pathology
Oxidative Stress*
Hepatocyte Growth Factor/*metabolism
Inflammation/*metabolism
Proto-Oncogene Proteins c-met/*metabolism
Animals ; Caspase 8/metabolism ; Hepatocytes/metabolism ; Lipotropic Agents/metabolism ; Mice ; Mice, Knockout ; Neutrophil Infiltration
Czasopismo naukowe
Tytuł :
GLP-1 secretion is increased by inflammatory stimuli in an IL-6-dependent manner, leading to hyperinsulinemia and blood glucose lowering.
Autorzy :
Kahles F; Department of Internal Medicine I, University Hospital Aachen, Aachen, Germany.
Meyer C; Department of Internal Medicine I, University Hospital Aachen, Aachen, Germany.
Möllmann J; Department of Internal Medicine I, University Hospital Aachen, Aachen, Germany.
Diebold S; Department of Internal Medicine I, University Hospital Aachen, Aachen, Germany.
Findeisen HM; Department of Internal Medicine I, University Hospital Aachen, Aachen, Germany.
Lebherz C; Department of Internal Medicine I, University Hospital Aachen, Aachen, Germany.
Trautwein C; Department of Internal Medicine III, University Hospital Aachen, Aachen, Germany.
Koch A; Department of Internal Medicine III, University Hospital Aachen, Aachen, Germany.
Tacke F; Department of Internal Medicine III, University Hospital Aachen, Aachen, Germany.
Marx N; Department of Internal Medicine I, University Hospital Aachen, Aachen, Germany.
Lehrke M; Department of Internal Medicine I, University Hospital Aachen, Aachen, Germany .
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Źródło :
Diabetes [Diabetes] 2014 Oct; Vol. 63 (10), pp. 3221-9. Date of Electronic Publication: 2014 Jun 19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Glucagon-Like Peptide 1/*metabolism
Hyperinsulinism/*metabolism
Inflammation/*metabolism
Interleukin-1beta/*metabolism
Interleukin-6/*metabolism
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Animals ; Blood Glucose/metabolism ; Female ; Glucagon-Like Peptide-1 Receptor ; Humans ; Interleukin-1beta/genetics ; Interleukin-6/genetics ; Lipopolysaccharides/pharmacology ; Male ; Mice, Knockout ; Middle Aged ; Peptide Fragments/pharmacology ; Receptors, Glucagon/metabolism ; Young Adult
Czasopismo naukowe
Tytuł :
Functional contribution of elevated circulating and hepatic non-classical CD14CD16 monocytes to inflammation and human liver fibrosis.
Autorzy :
Zimmermann HW; Department of Medicine III, University Hospital Aachen, Aachen, Germany.
Seidler S
Nattermann J
Gassler N
Hellerbrand C
Zernecke A
Tischendorf JJ
Luedde T
Weiskirchen R
Trautwein C
Tacke F
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Źródło :
PloS one [PLoS One] 2010 Jun 10; Vol. 5 (6), pp. e11049. Date of Electronic Publication: 2010 Jun 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Inflammation/*immunology
Lipopolysaccharide Receptors/*immunology
Liver Cirrhosis/*immunology
Monocytes/*immunology
Receptors, IgG/*immunology
Case-Control Studies ; Disease Progression ; Flow Cytometry ; Humans
Czasopismo naukowe
Tytuł :
Contribution of interleukin-6/gp 130 signaling in hepatocytes to the inflammatory response in mice infected with Streptococcus pyogenes.
Autorzy :
Klein C; Medizinische Klinik III, University Hospital Aachen, Rheinisch-Westfalisch Techniche Hochschule Aachen, Aachen, Germany. />Medina E
Sander L
Dierssen U
Roskams T
Mueller W
Trautwein C
Goldmann O
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Źródło :
The Journal of infectious diseases [J Infect Dis] 2007 Sep 01; Vol. 196 (5), pp. 755-62. Date of Electronic Publication: 2007 Jul 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cytokine Receptor gp130/*metabolism
Hepatocytes/*metabolism
Inflammation/*metabolism
Interleukin-6/*metabolism
Streptococcal Infections/*metabolism
Streptococcus pyogenes/*physiology
Animals ; Cytokine Receptor gp130/genetics ; Gene Deletion ; Gene Expression Regulation ; Mice ; Sepsis/metabolism ; Sepsis/microbiology ; Signal Transduction
Czasopismo naukowe
Tytuł :
Expression of tissue factor pathway inhibitor-2 in murine and human liver regulation during inflammation.
Autorzy :
Hisaka T; GREF, INSERM E 362 and IFR 66, Université Victor Segalen Bordeaux 2, Bordeaux, France.
Lardeux B
Lamireau T
Wüestefeld T
Lalor PF
Neaud V
Maurel P
Desmoulière A
Kisiel W
Trautwein C
Rosenbaum J
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Źródło :
Thrombosis and haemostasis [Thromb Haemost] 2004 Mar; Vol. 91 (3), pp. 569-75.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Glycoproteins/*biosynthesis
Inflammation/*metabolism
Liver/*metabolism
Acute-Phase Reaction ; Animals ; Antigens, CD/metabolism ; Blotting, Northern ; Cytokine Receptor gp130 ; Endopeptidases/metabolism ; Hepatocytes/metabolism ; Humans ; In Situ Hybridization ; Interleukin-6/metabolism ; Kinetics ; Lipopolysaccharides/metabolism ; Membrane Glycoproteins/metabolism ; Mice ; Mice, Inbred BALB C ; Mice, Knockout ; RNA, Messenger/metabolism ; Reverse Transcriptase Polymerase Chain Reaction ; Species Specificity ; Time Factors ; Up-Regulation
Czasopismo naukowe
Tytuł :
Akut-auf-chronisches Leberversagen: Eine neue Entität
Autorzy :
Zimmermann, H. W.
Trautwein, C.
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Alternatywny tytuł :
Acute-on-chronic liver failure: A new entity
Źródło :
Der Gastroenterologe: Zeitschrift für Gastroenterologie und Hepatologie. February 2016 11(1):28-33
Czasopismo naukowe

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