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Tytuł :
Aerosol Inhalation Delivery of Triazavirin in Mice: Outlooks for Advanced Therapy Against Novel Viral Infections.
Autorzy :
Valiulin SV; Voevodsky Institute of Chemical Kinetics and Combustion, SB RAS, Novosibirsk 630090, Russia.
Onischuk AA; Voevodsky Institute of Chemical Kinetics and Combustion, SB RAS, Novosibirsk 630090, Russia.
Dubtsov SN; Voevodsky Institute of Chemical Kinetics and Combustion, SB RAS, Novosibirsk 630090, Russia.
Baklanov AM; Voevodsky Institute of Chemical Kinetics and Combustion, SB RAS, Novosibirsk 630090, Russia.
An'kov SV; Vorozhtsov Institute of Organic Chemistry, SB RAS, Novosibirsk 630090, Russia.
Plokhotnichenko ME; Voevodsky Institute of Chemical Kinetics and Combustion, SB RAS, Novosibirsk 630090, Russia.
Tolstikova TG; Vorozhtsov Institute of Organic Chemistry, SB RAS, Novosibirsk 630090, Russia.
Dultseva GG; Voevodsky Institute of Chemical Kinetics and Combustion, SB RAS, Novosibirsk 630090, Russia. Electronic address: .
Rusinov VL; Postovskii Institute of Organic Synthesis, UrB RAS, Yekaterinburg 620137, Russia.
Charushin VN; Postovskii Institute of Organic Synthesis, UrB RAS, Yekaterinburg 620137, Russia.
Fomin VM; Khristianovich Institute of Theoretical and Applied Mechanics, SB RAS, Novosibirsk 630090, Russia.
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Źródło :
Journal of pharmaceutical sciences [J Pharm Sci] 2021 Mar; Vol. 110 (3), pp. 1316-1322. Date of Electronic Publication: 2020 Nov 26.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Nebulizers and Vaporizers*
Aerosols/*administration & dosage
Antiviral Agents/*administration & dosage
Azoles/*administration & dosage
Triazines/*administration & dosage
Administration, Inhalation ; Administration, Oral ; Aerosols/pharmacokinetics ; Animals ; Antiviral Agents/blood ; Antiviral Agents/pharmacokinetics ; Azoles/blood ; Azoles/pharmacokinetics ; Biological Availability ; COVID-19/drug therapy ; Drug Delivery Systems/instrumentation ; Drug Elimination Routes ; Equipment Design ; Humans ; Male ; Mice ; Triazines/blood ; Triazines/pharmacokinetics
Czasopismo naukowe
Tytuł :
The Antiproliferative and Apoptotic Effect of a Novel Synthesized S -Triazine Dipeptide Series, and Toxicity Screening in Zebrafish Embryos.
Autorzy :
Malebari AM; Department of Pharmaceutical Chemistry, College of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
Abd Alhameed R; Department of Chemistry, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia.
Almarhoon Z; Department of Chemistry, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia.
Farooq M; Bio-Products Research Chair, Department of Zoology, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia.
Wadaan MAM; Bio-Products Research Chair, Department of Zoology, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia.; Deanship of Postgraduate Studies and Scientific Research, Almaarefa University, Riyadh 11597, Saudi Arabia.
Sharma A; KwaZulu-Natal Research Innovation and Sequencing Platform (KRISP), School of Laboratory Medicine and Medical Sciences, College of Health Sciences, University of KwaZulu-Natal, Durban 4041, South Africa.; Peptide Science Laboratory, School of Chemistry and Physics, University of KwaZulu-Natal, Durban 4001, South Africa.
de la Torre BG; KwaZulu-Natal Research Innovation and Sequencing Platform (KRISP), School of Laboratory Medicine and Medical Sciences, College of Health Sciences, University of KwaZulu-Natal, Durban 4041, South Africa.; Peptide Science Laboratory, School of Chemistry and Physics, University of KwaZulu-Natal, Durban 4001, South Africa.
Albericio F; Department of Chemistry, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia.; Peptide Science Laboratory, School of Chemistry and Physics, University of KwaZulu-Natal, Durban 4001, South Africa.; CIBER-BBN (Networking Centre on Bioengineering, Biomaterials and Nanomedicine) and Department of Organic Chemistry, University of Barcelona, 08028 Barcelona, Spain.; Institute for Advanced Chemistry of Catalonia (IQAC-CSIC), 08034 Barcelona, Spain.
El-Faham A; Department of Chemistry, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia.; Chemistry Department, Faculty of Science, Alexandria University, P.O. Box 426, Ibrahimia, Alexandria 12321, Egypt.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Feb 22; Vol. 26 (4). Date of Electronic Publication: 2021 Feb 22.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents/*pharmacology
Apoptosis/*drug effects
Dipeptides/*pharmacology
Triazines/*pharmacology
Animals ; Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Cell Cycle Checkpoints/drug effects ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Cells, Cultured ; Dipeptides/chemical synthesis ; Dipeptides/chemistry ; Drug Evaluation, Preclinical ; Drug Screening Assays, Antitumor ; Humans ; Molecular Structure ; Triazines/chemical synthesis ; Triazines/chemistry ; Zebrafish/embryology
Czasopismo naukowe
Tytuł :
Biguanide-Based Synthesis of 1,3,5-Triazine Derivatives with Anticancer Activity and 1,3,5-Triazine Incorporated Calcium Citrate Nanoparticles.
Autorzy :
Chalermnon M; Department of Chemistry, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand.
Cherdchom S; Department of Pharmacy Practice, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Phayathai Road, Wangmai, Patumwan, Bangkok 10330, Thailand.; NanoMedicine Research Unit, Department of Anatomy, Faculty of Medicine, Chulalongkorn University, Rama 4 Road, Patumwan, Bangkok 10330, Thailand.
Sereemaspun A; Chula Medical Innovation Centre (CMIC), Nanomedicine Research Unit, Department of Anatomy, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand.
Rojanathanes R; Centre of Excellence in Materials and Bio-Interfaces, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand.
Khotavivattana T; Centre of Excellence in Natural Products Chemistry, Department of Chemistry, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Feb 15; Vol. 26 (4). Date of Electronic Publication: 2021 Feb 15.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents/*pharmacology
Biguanides/*chemistry
Calcium Citrate/*chemistry
Nanoparticles/*chemistry
Triazines/*chemical synthesis
Triazines/*pharmacology
Cell Line, Tumor ; Drug Liberation ; Humans ; Nanoparticles/ultrastructure ; Spectroscopy, Fourier Transform Infrared ; Thermogravimetry ; Triazines/chemistry
Czasopismo naukowe
Tytuł :
Clinical Outcomes and Plasma Concentrations of Baloxavir Marboxil and Favipiravir in COVID-19 Patients: An Exploratory Randomized, Controlled Trial.
Autorzy :
Lou Y; State Key Laboratory for diagnosis and treatment of infectious diseases, Key Laboratory for Drug Evaluation and Clinical Research of Zhejiang Province, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.
Liu L; State Key Laboratory for diagnosis and treatment of infectious diseases, Key Laboratory for Drug Evaluation and Clinical Research of Zhejiang Province, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.
Yao H; State Key Laboratory for diagnosis and treatment of infectious diseases, Key Laboratory for Drug Evaluation and Clinical Research of Zhejiang Province, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.
Hu X; State Key Laboratory for diagnosis and treatment of infectious diseases, Key Laboratory for Drug Evaluation and Clinical Research of Zhejiang Province, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.
Su J; State Key Laboratory for diagnosis and treatment of infectious diseases, Key Laboratory for Drug Evaluation and Clinical Research of Zhejiang Province, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.
Xu K; State Key Laboratory for diagnosis and treatment of infectious diseases, Key Laboratory for Drug Evaluation and Clinical Research of Zhejiang Province, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.
Luo R; State Key Laboratory for diagnosis and treatment of infectious diseases, Key Laboratory for Drug Evaluation and Clinical Research of Zhejiang Province, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.
Yang X; State Key Laboratory for diagnosis and treatment of infectious diseases, Key Laboratory for Drug Evaluation and Clinical Research of Zhejiang Province, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.
He L; State Key Laboratory for diagnosis and treatment of infectious diseases, Key Laboratory for Drug Evaluation and Clinical Research of Zhejiang Province, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.
Lu X; State Key Laboratory for diagnosis and treatment of infectious diseases, Key Laboratory for Drug Evaluation and Clinical Research of Zhejiang Province, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.
Zhao Q; State Key Laboratory for diagnosis and treatment of infectious diseases, Key Laboratory for Drug Evaluation and Clinical Research of Zhejiang Province, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.
Liang T; State Key Laboratory for diagnosis and treatment of infectious diseases, Key Laboratory for Drug Evaluation and Clinical Research of Zhejiang Province, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.
Qiu Y; State Key Laboratory for diagnosis and treatment of infectious diseases, Key Laboratory for Drug Evaluation and Clinical Research of Zhejiang Province, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China. Electronic address: .
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Źródło :
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences [Eur J Pharm Sci] 2021 Feb 01; Vol. 157, pp. 105631. Date of Electronic Publication: 2020 Oct 25.
Typ publikacji :
Journal Article; Randomized Controlled Trial
MeSH Terms :
Amides*/administration & dosage
Amides*/blood
Amides*/pharmacokinetics
COVID-19*/blood
COVID-19*/diagnosis
COVID-19*/drug therapy
COVID-19*/physiopathology
Dibenzothiepins*/administration & dosage
Dibenzothiepins*/blood
Dibenzothiepins*/pharmacokinetics
Morpholines*/administration & dosage
Morpholines*/blood
Morpholines*/pharmacokinetics
Pyrazines*/administration & dosage
Pyrazines*/blood
Pyrazines*/pharmacokinetics
Pyridones*/administration & dosage
Pyridones*/blood
Pyridones*/pharmacokinetics
Triazines*/administration & dosage
Triazines*/blood
Triazines*/pharmacokinetics
Antiviral Agents/administration & dosage ; Antiviral Agents/blood ; Antiviral Agents/pharmacokinetics ; Drug Monitoring/methods ; Female ; Humans ; Inhibitory Concentration 50 ; Male ; Middle Aged ; SARS-CoV-2/drug effects ; SARS-CoV-2/isolation & purification ; SARS-CoV-2/physiology ; Symptom Assessment ; Treatment Outcome ; Viral Load/drug effects
Czasopismo naukowe
Tytuł :
A sodium dichloroisocyanurate-based conditioning process for the improvement of sludge dewaterability and mechanism studies.
Autorzy :
Dong Y; School of Environmental Science & Engineering, Shanghai Jiao Tong University, Shanghai, 200240, China.
Shen Y; School of Environmental Science & Engineering, Shanghai Jiao Tong University, Shanghai, 200240, China.
Ge D; School of Environmental Science & Engineering, Shanghai Jiao Tong University, Shanghai, 200240, China.
Bian C; School of Environmental Science & Engineering, Shanghai Jiao Tong University, Shanghai, 200240, China.
Yuan H; School of Environmental Science & Engineering, Shanghai Jiao Tong University, Shanghai, 200240, China.
Zhu N; School of Environmental Science & Engineering, Shanghai Jiao Tong University, Shanghai, 200240, China; Shanghai Institute of Pollution Control and Ecological Security, Shanghai, 200092, China. Electronic address: .
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Źródło :
Journal of environmental management [J Environ Manage] 2021 Apr 15; Vol. 284, pp. 112020. Date of Electronic Publication: 2021 Jan 25.
Typ publikacji :
Journal Article
MeSH Terms :
Sewage*
Triazines*
Particle Size ; Waste Disposal, Fluid ; Water
Czasopismo naukowe
Tytuł :
Vortex-assisted solid-phase extraction based on metal-organic framework/chitosan-functionalized hydrophilic sponge column for determination of triazine herbicides in environmental water by liquid chromatography-tandem mass spectrometry.
Autorzy :
Jiang Y; College of Chemistry, Jilin University, Changchun 130012, China.
Qin Z; Hunan Warrant Pharmaceutical Company Ltd., Changsha 410000, China.
Liang F; Department of Pharmacy, Changchun Medical College, Changchun 130031, China.
Li J; College of Chemistry, Jilin University, Changchun 130012, China.
Sun Y; College of Chemistry, Jilin University, Changchun 130012, China.
Wang X; College of Chemistry, Jilin University, Changchun 130012, China.
Ma P; College of Chemistry, Jilin University, Changchun 130012, China. Electronic address: .
Song D; College of Chemistry, Jilin University, Changchun 130012, China. Electronic address: .
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Źródło :
Journal of chromatography. A [J Chromatogr A] 2021 Feb 08; Vol. 1638, pp. 461887. Date of Electronic Publication: 2021 Jan 06.
Typ publikacji :
Journal Article
MeSH Terms :
Hydrophobic and Hydrophilic Interactions*
Herbicides/*analysis
Metal-Organic Frameworks/*chemistry
Solid Phase Extraction/*methods
Tandem Mass Spectrometry/*methods
Triazines/*analysis
Water Pollutants, Chemical/*analysis
Adsorption ; Chromatography, High Pressure Liquid/methods ; Chromatography, Liquid ; Hydrogen-Ion Concentration ; Reproducibility of Results ; Salts/chemistry ; Solvents/chemistry ; Time Factors ; Triazines/chemistry
Czasopismo naukowe
Tytuł :
[The Antileukemia Activity of ZSTK474 on U937 Cells].
Autorzy :
Chen T; School of Pharmacy, Tianjin Medical University, Tianjin 300070, China.
Zhou QX; School of Pharmacy, Tianjin Medical University, Tianjin 300070, China.
Qiu YL; School of Pharmacy, Tianjin Medical University, Tianjin 300070, China E-mail: .
Kong DX; School of Pharmacy, Tianjin Medical University, Tianjin 300070, China E-mail: .
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Źródło :
Zhongguo shi yan xue ye xue za zhi [Zhongguo Shi Yan Xue Ye Xue Za Zhi] 2021 Feb; Vol. 29 (1), pp. 17-25.
Typ publikacji :
Journal Article
MeSH Terms :
Phosphatidylinositol 3-Kinases*
Triazines*
Apoptosis ; Cell Line, Tumor ; Cell Proliferation ; Glycogen Synthase Kinase 3 beta ; Humans ; Proto-Oncogene Proteins c-akt ; U937 Cells
Czasopismo naukowe
Tytuł :
Xofluza Now Indicated to Prevent Influenza.
Autorzy :
Aschenbrenner DS; Diane S. Aschenbrenner is an assistant professor at Notre Dame of Maryland University in Baltimore. She also coordinates Drug Watch: .
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Źródło :
The American journal of nursing [Am J Nurs] 2021 Feb 01; Vol. 121 (2), pp. 26-27.
Typ publikacji :
Journal Article
MeSH Terms :
Dibenzothiepins/*pharmacology
Influenza, Human/*drug therapy
Influenza, Human/*prevention & control
Morpholines/*pharmacology
Pyridones/*pharmacology
Triazines/*pharmacology
Antiviral Agents/pharmacology ; Antiviral Agents/therapeutic use ; Dibenzothiepins/therapeutic use ; Humans ; Morpholines/therapeutic use ; Pyridones/therapeutic use ; Triazines/therapeutic use
Czasopismo naukowe
Tytuł :
Highly-selective complex matrices removal via a modified QuEChERS for determination of triazine herbicide residues and risk assessment in bivalves.
Autorzy :
Yu X; State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products, Ningbo University, Ningbo 315211, PR China; School of Marine Sciences, Ningbo University, Ningbo 315211, PR China. Electronic address: .
Zhang R; State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products, Ningbo University, Ningbo 315211, PR China; School of Marine Sciences, Ningbo University, Ningbo 315211, PR China. Electronic address: .
Liu H; State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products, Ningbo University, Ningbo 315211, PR China; School of Marine Sciences, Ningbo University, Ningbo 315211, PR China. Electronic address: .
Zhang Z; State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products, Ningbo University, Ningbo 315211, PR China; School of Marine Sciences, Ningbo University, Ningbo 315211, PR China. Electronic address: .
Shi X; State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products, Ningbo University, Ningbo 315211, PR China; School of Marine Sciences, Ningbo University, Ningbo 315211, PR China. Electronic address: .
Sun A; School of Marine Sciences, Ningbo University, Ningbo 315211, PR China. Electronic address: .
Chen J; State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products, Ningbo University, Ningbo 315211, PR China; School of Marine Sciences, Ningbo University, Ningbo 315211, PR China. Electronic address: .
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Źródło :
Food chemistry [Food Chem] 2021 Jun 15; Vol. 347, pp. 129030. Date of Electronic Publication: 2021 Jan 12.
Typ publikacji :
Journal Article
MeSH Terms :
Bivalvia/*chemistry
Pesticide Residues/*analysis
Solid Phase Extraction/*methods
Triazines/*analysis
Animals ; China ; Chromatography, Gas/methods ; Herbicides/analysis ; Tandem Mass Spectrometry/methods ; Triazines/isolation & purification
Czasopismo naukowe
Tytuł :
Cystoisospora suis merozoite development assay for screening of drug efficacy in vitro.
Autorzy :
Joachim A; Institute of Parasitology, Department of Pathobiology, University of Veterinary Medicine Vienna, Austria. Electronic address: .
Ruttkowski B; Institute of Parasitology, Department of Pathobiology, University of Veterinary Medicine Vienna, Austria.
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Źródło :
Experimental parasitology [Exp Parasitol] 2021 Jan; Vol. 220, pp. 108035. Date of Electronic Publication: 2020 Nov 12.
Typ publikacji :
Journal Article
MeSH Terms :
Coccidiosis/*veterinary
Coccidiostats/*pharmacology
Sarcocystidae/*drug effects
Swine Diseases/*parasitology
Triazines/*pharmacology
Animals ; Cell Line ; Coccidiosis/drug therapy ; Coccidiosis/parasitology ; Coccidiostats/metabolism ; Coccidiostats/therapeutic use ; Dose-Response Relationship, Drug ; Drug Evaluation, Preclinical/veterinary ; Drug Resistance ; Inhibitory Concentration 50 ; Merozoites/drug effects ; Merozoites/growth & development ; Pilot Projects ; Piperidines/pharmacology ; Pyrimidines/pharmacology ; Quinolines/pharmacology ; Real-Time Polymerase Chain Reaction ; Sarcocystidae/growth & development ; Sulfones/chemistry ; Sulfoxides/chemistry ; Swine ; Swine Diseases/drug therapy ; Triazines/metabolism ; Triazines/therapeutic use
Czasopismo naukowe
Tytuł :
Prevention of melamine-induced hepatorenal impairment by an ethanolic extract of Moringa oleifera: Changes in KIM-1, TIMP-1, oxidative stress, apoptosis, and inflammation-related genes.
Autorzy :
Abd-Elhakim YM; Department of Forensic Medicine and Toxicology, Faculty of Veterinary Medicine, Zagazig University, Zagazig, Egypt. Electronic address: .
Mohamed WAM; Department of Clinical Pathology, Faculty of Veterinary Medicine, Zagazig University, Zagazig, Egypt.
El Bohi KM; Department of Forensic Medicine and Toxicology, Faculty of Veterinary Medicine, Zagazig University, Zagazig, Egypt.
Ali HA; Department of Biochemistry, Faculty of Veterinary Medicine, Zagazig University, Zagazig, Egypt; Department of Biochemistry, Collage of Science, University of Jeddah, Jeddah, Saudi Arabia.
Mahmoud FA; Department of Pharmacology, Faculty of Veterinary Medicine, Zagazig University, Egypt.
Saber TM; Department of Forensic Medicine and Toxicology, Faculty of Veterinary Medicine, Zagazig University, Zagazig, Egypt.
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Źródło :
Gene [Gene] 2021 Jan 05; Vol. 764, pp. 145083. Date of Electronic Publication: 2020 Aug 26.
Typ publikacji :
Journal Article
MeSH Terms :
Chemical and Drug Induced Liver Injury/*prevention & control
Moringa oleifera/*chemistry
Plant Extracts/*administration & dosage
Renal Insufficiency/*prevention & control
Triazines/*toxicity
Administration, Oral ; Animals ; Apoptosis/drug effects ; Apoptosis/genetics ; Apoptosis/immunology ; Cell Adhesion Molecules/metabolism ; Chemical and Drug Induced Liver Injury/blood ; Chemical and Drug Induced Liver Injury/etiology ; Disease Models, Animal ; Environmental Pollutants/toxicity ; Ethanol/chemistry ; Food Contamination ; Gene Expression Regulation/drug effects ; Humans ; Inflammation Mediators/blood ; Inflammation Mediators/metabolism ; Male ; Oxidative Stress/drug effects ; Oxidative Stress/genetics ; Oxidative Stress/immunology ; Plant Extracts/chemistry ; Plant Extracts/isolation & purification ; Rats ; Renal Insufficiency/blood ; Renal Insufficiency/chemically induced ; Tissue Inhibitor of Metalloproteinase-1/metabolism ; Triazines/administration & dosage
Czasopismo naukowe
Tytuł :
Evaluation of Baloxavir Marboxil and Peramivir for the Treatment of High Pathogenicity Avian Influenza in Chickens.
Autorzy :
Twabela A; Laboratory of Microbiology, Department of Disease Control, Faculty of Veterinary Medicine, Hokkaido University, Sapporo 060-0818, Japan.; Virology Service, Central Veterinary Laboratory of Kinshasa, Ministry of Fisheries and Livestock, Kinshasa I/Gombe 012, Democratic Republic of the Congo.
Okamatsu M; Laboratory of Microbiology, Department of Disease Control, Faculty of Veterinary Medicine, Hokkaido University, Sapporo 060-0818, Japan.
Matsuno K; International Collaboration Unit, Research Center for Zoonosis Control, Hokkaido University, Sapporo 011-0020, Japan.; Unit of Risk Analysis and Management, Research Center for Zoonotic Control, Hokkaido University, Sapporo 011-0020, Japan.
Isoda N; Laboratory of Microbiology, Department of Disease Control, Faculty of Veterinary Medicine, Hokkaido University, Sapporo 060-0818, Japan.
Sakoda Y; Laboratory of Microbiology, Department of Disease Control, Faculty of Veterinary Medicine, Hokkaido University, Sapporo 060-0818, Japan.; International Collaboration Unit, Research Center for Zoonosis Control, Hokkaido University, Sapporo 011-0020, Japan.
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Źródło :
Viruses [Viruses] 2020 Dec 08; Vol. 12 (12). Date of Electronic Publication: 2020 Dec 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Acids, Carbocyclic/*pharmacology
Antiviral Agents/*pharmacology
Chickens/*virology
Dibenzothiepins/*pharmacology
Guanidines/*pharmacology
Influenza A virus/*drug effects
Influenza in Birds/*drug therapy
Influenza in Birds/*virology
Morpholines/*pharmacology
Pyridones/*pharmacology
Triazines/*pharmacology
Acids, Carbocyclic/therapeutic use ; Animals ; Antiviral Agents/therapeutic use ; Dibenzothiepins/therapeutic use ; Drug Monitoring ; Guanidines/therapeutic use ; Influenza in Birds/mortality ; Morpholines/therapeutic use ; Organ Specificity ; Pyridones/therapeutic use ; Time-to-Treatment ; Treatment Outcome ; Triazines/therapeutic use ; Virus Shedding
Czasopismo naukowe
Tytuł :
Evaluation of cyromazine transferred from feed to chicken products and subsequent assessment of dietary risks to Chinese consumers.
Autorzy :
Ji X; State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products, National Reference Laboratory for Agricultural Testing (Pesticide Residues), Agricultural Ministry Key Laboratory for Pesticide Residue Detection, Zhejiang Province Key Laboratory for Food Safety, Institute of Agro-product Safety and Nutrition, Zhejiang Academy of Agricultural Sciences, Hangzhou, Zhejiang, 310021, P. R. China.
Yang H; State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products, National Reference Laboratory for Agricultural Testing (Pesticide Residues), Agricultural Ministry Key Laboratory for Pesticide Residue Detection, Zhejiang Province Key Laboratory for Food Safety, Institute of Agro-product Safety and Nutrition, Zhejiang Academy of Agricultural Sciences, Hangzhou, Zhejiang, 310021, P. R. China.
Lyu W; State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products, National Reference Laboratory for Agricultural Testing (Pesticide Residues), Agricultural Ministry Key Laboratory for Pesticide Residue Detection, Zhejiang Province Key Laboratory for Food Safety, Institute of Agro-product Safety and Nutrition, Zhejiang Academy of Agricultural Sciences, Hangzhou, Zhejiang, 310021, P. R. China.
Wang J; State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products, National Reference Laboratory for Agricultural Testing (Pesticide Residues), Agricultural Ministry Key Laboratory for Pesticide Residue Detection, Zhejiang Province Key Laboratory for Food Safety, Institute of Agro-product Safety and Nutrition, Zhejiang Academy of Agricultural Sciences, Hangzhou, Zhejiang, 310021, P. R. China.
Wang X; State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products, National Reference Laboratory for Agricultural Testing (Pesticide Residues), Agricultural Ministry Key Laboratory for Pesticide Residue Detection, Zhejiang Province Key Laboratory for Food Safety, Institute of Agro-product Safety and Nutrition, Zhejiang Academy of Agricultural Sciences, Hangzhou, Zhejiang, 310021, P. R. China.
Wang X; State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products, National Reference Laboratory for Agricultural Testing (Pesticide Residues), Agricultural Ministry Key Laboratory for Pesticide Residue Detection, Zhejiang Province Key Laboratory for Food Safety, Institute of Agro-product Safety and Nutrition, Zhejiang Academy of Agricultural Sciences, Hangzhou, Zhejiang, 310021, P. R. China.
Qian M; State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products, National Reference Laboratory for Agricultural Testing (Pesticide Residues), Agricultural Ministry Key Laboratory for Pesticide Residue Detection, Zhejiang Province Key Laboratory for Food Safety, Institute of Agro-product Safety and Nutrition, Zhejiang Academy of Agricultural Sciences, Hangzhou, Zhejiang, 310021, P. R. China.
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Źródło :
Journal of food science [J Food Sci] 2020 Dec; Vol. 85 (12), pp. 4396-4406. Date of Electronic Publication: 2020 Nov 20.
Typ publikacji :
Journal Article
MeSH Terms :
Animal Feed/*analysis
Eggs/*analysis
Food Contamination/*analysis
Meat/*analysis
Triazines/*toxicity
Animals ; Chickens ; China ; Food Safety ; Humans ; No-Observed-Adverse-Effect Level ; Risk Assessment ; Triazines/analysis
Czasopismo naukowe
Tytuł :
Efficient removal of three dyes using porous covalent triazine frameworks: adsorption mechanism and role of pore distribution.
Autorzy :
An F; State Power Environmental Protection Research Institute Co. Ltd, Nanjing 210031, China.
Liu J; School of Environmental Science, Nanjing XiaoZhuang University, Nanjing 211171, China E-mail: .
Xu Z; State Key Laboratory of Pollution Control and Resource Reuse, and School of the Environment, Nanjing University, Nanjing 210093, China.
Zheng S; State Key Laboratory of Pollution Control and Resource Reuse, and School of the Environment, Nanjing University, Nanjing 210093, China.
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Źródło :
Water science and technology : a journal of the International Association on Water Pollution Research [Water Sci Technol] 2020 Dec; Vol. 82 (12), pp. 3023-3031.
Typ publikacji :
Journal Article
MeSH Terms :
Coloring Agents*
Triazines*
Adsorption ; Porosity ; Surface Properties
Czasopismo naukowe
Tytuł :
1,3,5-Triaryl-1,3,5-Triazinane-2,4,6-Trithiones: Synthesis, Electronic Structure and Linear Optical Properties.
Autorzy :
Rabouel I; ISCR (Institut des Sciences Chimiques de Rennes), Université de Rennes, CNRS, UMR 6226, 35000 Rennes, France.
Richy N; ISCR (Institut des Sciences Chimiques de Rennes), Université de Rennes, CNRS, UMR 6226, 35000 Rennes, France.
Amar A; Département de Chimie, Faculté des Sciences, Université Mouloud Mammeri, 15000 Tizi-Ouzou, Algeria.; Faculté de Chimie, Université des Sciences et de la Technologie Houari-Boumediene, 16111 Bab-Ezzouar, Algeria.
Boucekkine A; ISCR (Institut des Sciences Chimiques de Rennes), Université de Rennes, CNRS, UMR 6226, 35000 Rennes, France.
Roisnel T; ISCR (Institut des Sciences Chimiques de Rennes), Université de Rennes, CNRS, UMR 6226, 35000 Rennes, France.
Mongin O; ISCR (Institut des Sciences Chimiques de Rennes), Université de Rennes, CNRS, UMR 6226, 35000 Rennes, France.
Humphrey MG; Research School of Chemistry, Australian National University, Canberra, ACT 2601, Australia.
Paul F; ISCR (Institut des Sciences Chimiques de Rennes), Université de Rennes, CNRS, UMR 6226, 35000 Rennes, France.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2020 Nov 23; Vol. 25 (22). Date of Electronic Publication: 2020 Nov 23.
Typ publikacji :
Journal Article
MeSH Terms :
Triazines/*chemistry
Chemistry Techniques, Synthetic ; Density Functional Theory ; Models, Theoretical ; Molecular Structure ; Optical Phenomena ; Spectrum Analysis ; Triazines/chemical synthesis
Czasopismo naukowe
Tytuł :
Financial Implications of Avapritinib for Treatment of Unresectable Gastrointestinal Stromal Tumors in Patients With a PDGFRA Exon 18 Variant or After 3 Previous Therapies in a Hypothetical US Health Plan.
Autorzy :
Proudman D; Analysis Group Inc, Menlo Park, California.
Miller A; Analysis Group Inc, Menlo Park, California.
Nellesen D; Analysis Group Inc, Menlo Park, California.
Gomes A; Analysis Group Inc, Menlo Park, California.
Mankoski R; Blueprint Medicines Corporation, Cambridge, Massachusetts.
Norregaard C; Blueprint Medicines Corporation, Cambridge, Massachusetts.
Sullivan E; Blueprint Medicines Corporation, Cambridge, Massachusetts.
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Źródło :
JAMA network open [JAMA Netw Open] 2020 Nov 02; Vol. 3 (11), pp. e2025866. Date of Electronic Publication: 2020 Nov 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antineoplastic Agents/*economics
Gastrointestinal Neoplasms/*drug therapy
Gastrointestinal Stromal Tumors/*drug therapy
Managed Care Programs/*economics
Pyrazoles/*economics
Pyrroles/*economics
Triazines/*economics
Antineoplastic Agents/therapeutic use ; Budgets ; Cost-Benefit Analysis ; Formularies as Topic ; Gastrointestinal Neoplasms/pathology ; Gastrointestinal Stromal Tumors/genetics ; Gastrointestinal Stromal Tumors/pathology ; Gastrointestinal Stromal Tumors/secondary ; Humans ; Imatinib Mesylate/economics ; Imatinib Mesylate/therapeutic use ; Medicaid ; Medicare ; Molecular Diagnostic Techniques/economics ; Phenylurea Compounds/economics ; Phenylurea Compounds/therapeutic use ; Pyrazoles/therapeutic use ; Pyridines/economics ; Pyridines/therapeutic use ; Pyrimidines/economics ; Pyrimidines/therapeutic use ; Pyrroles/therapeutic use ; Receptor, Platelet-Derived Growth Factor alpha/genetics ; Sulfonamides/economics ; Sulfonamides/therapeutic use ; Sunitinib/economics ; Sunitinib/therapeutic use ; Treatment Failure ; Triazines/therapeutic use ; United States
Czasopismo naukowe
Tytuł :
Aminotriazines with indole motif as novel, 5-HT 7 receptor ligands with atypical binding mode.
Autorzy :
Kułaga D; Faculty of Chemical Engineering and Technology, Institute of Organic Chemistry and Technology, Cracow University of Technology, 24 Warszawska Street, 31-155 Kraków, Poland. Electronic address: .
Jaśkowska J; Faculty of Chemical Engineering and Technology, Institute of Organic Chemistry and Technology, Cracow University of Technology, 24 Warszawska Street, 31-155 Kraków, Poland.
Satała G; Department of Medicinal Chemistry, Maj Institute of Pharmacology, Polish Academy of Sciences, 12 Smętna Street, 31-343 Kraków, Poland.
Latacz G; Department of Technology and Biotechnology of Drugs, Jagiellonian University Medical College, 9 Medyczna Street, 30-688 Kraków, Poland.
Śliwa P; Faculty of Chemical Engineering and Technology, Institute of Organic Chemistry and Technology, Cracow University of Technology, 24 Warszawska Street, 31-155 Kraków, Poland.
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Źródło :
Bioorganic chemistry [Bioorg Chem] 2020 Nov; Vol. 104, pp. 104254. Date of Electronic Publication: 2020 Sep 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Indoles/*pharmacology
Receptors, Serotonin/*metabolism
Serotonin Antagonists/*pharmacology
Serotonin Receptor Agonists/*pharmacology
Triazines/*pharmacology
Binding Sites/drug effects ; Dose-Response Relationship, Drug ; Hep G2 Cells ; Humans ; Indoles/chemistry ; Ligands ; Models, Molecular ; Molecular Structure ; Serotonin Antagonists/chemical synthesis ; Serotonin Antagonists/chemistry ; Serotonin Receptor Agonists/chemical synthesis ; Serotonin Receptor Agonists/chemistry ; Structure-Activity Relationship ; Triazines/chemistry
Czasopismo naukowe
Tytuł :
Non-rigid Diarylmethyl Analogs of Baloxavir as Cap-Dependent Endonuclease Inhibitors of Influenza Viruses.
Autorzy :
Ivashchenko AA; Chemical Diversity Research Institute, Rabochaya Street 2a, Khimki, Moscow Region 141401, Russia.; ChemDiv, 6605 Nancy Ridge Drive, San Diego, California 92121, United States.; Moscow Institute of Physics and Technology (State University), 9 Institutskiy Lane, Dolgoprudny City, Moscow Region 141700, Russia.
Mitkin OD; Chemical Diversity Research Institute, Rabochaya Street 2a, Khimki, Moscow Region 141401, Russia.
Jones JC; Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States.
Nikitin AV; Chemical Diversity Research Institute, Rabochaya Street 2a, Khimki, Moscow Region 141401, Russia.
Koryakova AG; Chemical Diversity Research Institute, Rabochaya Street 2a, Khimki, Moscow Region 141401, Russia.
Ryakhovskiy A; Chemical Diversity Research Institute, Rabochaya Street 2a, Khimki, Moscow Region 141401, Russia.
Karapetian RN; Chemical Diversity Research Institute, Rabochaya Street 2a, Khimki, Moscow Region 141401, Russia.
Kravchenko DV; Chemical Diversity Research Institute, Rabochaya Street 2a, Khimki, Moscow Region 141401, Russia.
Aladinskiy V; Moscow Institute of Physics and Technology (State University), 9 Institutskiy Lane, Dolgoprudny City, Moscow Region 141700, Russia.
Leneva IA; I. Mechnikov Research Institute for Vaccines and Sera, 5a Malyy Kazennyy Lane, Moscow 105064, Russia.
Falynskova IN; I. Mechnikov Research Institute for Vaccines and Sera, 5a Malyy Kazennyy Lane, Moscow 105064, Russia.
Glubokova EA; I. Mechnikov Research Institute for Vaccines and Sera, 5a Malyy Kazennyy Lane, Moscow 105064, Russia.
Govorkova EA; Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States.
Ivachtchenko AV; Chemical Diversity Research Institute, Rabochaya Street 2a, Khimki, Moscow Region 141401, Russia.; ChemDiv, 6605 Nancy Ridge Drive, San Diego, California 92121, United States.; ASAVI LLC, 1835 E. Hallandale Beach Blvd, #442, Hallandale Beach, Florida 33009, United States.
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Źródło :
Journal of medicinal chemistry [J Med Chem] 2020 Sep 10; Vol. 63 (17), pp. 9403-9420. Date of Electronic Publication: 2020 Aug 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Dibenzothiepins/*chemistry
Dibenzothiepins/*pharmacology
Endonucleases/*antagonists & inhibitors
Enzyme Inhibitors/*chemistry
Enzyme Inhibitors/*pharmacology
Influenza A Virus, H1N1 Subtype/*enzymology
Morpholines/*chemistry
Morpholines/*pharmacology
Pyridones/*chemistry
Pyridones/*pharmacology
Triazines/*chemistry
Triazines/*pharmacology
Animals ; Dibenzothiepins/adverse effects ; Dibenzothiepins/pharmacokinetics ; Endonucleases/chemistry ; Enzyme Inhibitors/adverse effects ; Enzyme Inhibitors/pharmacokinetics ; Female ; HEK293 Cells ; Humans ; Influenza A Virus, H1N1 Subtype/drug effects ; Mice ; Models, Molecular ; Morpholines/adverse effects ; Morpholines/pharmacokinetics ; Protein Conformation ; Pyridones/adverse effects ; Pyridones/pharmacokinetics ; Tissue Distribution ; Triazines/adverse effects ; Triazines/pharmacokinetics
Czasopismo naukowe

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