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Tytuł:
Activity of a multitargeted chemo-switch regimen (sorafenib, gemcitabine, and metronomic capecitabine) in metastatic renal-cell carcinoma: a phase 2 study (SOGUG-02-06)
Autorzy:
Bellmunt J (AUTHOR)
Trigo JM (AUTHOR)
Calvo E (AUTHOR)
Carles J (AUTHOR)
Pérez-Gracia JL (AUTHOR)
Rubió J (AUTHOR)
Virizuela JA (AUTHOR)
López R (AUTHOR)
Lázaro M (AUTHOR)
Albanell J (AUTHOR)
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Źródło:
Lancet Oncology. Apr2010, Vol. 11 Issue 4, p350-357. 8p.
Czasopismo naukowe
Szczegóły
Tytuł:
Determination of essential biomarkers in lung cancer: a real-world data study in Spain with demographic, clinical, epidemiological and pathological characteristics.
Autorzy:
Provencio M; Medical Oncology Department, Hospital Universitario Puerta de Hierro-Majadahonda, C/ Manuel de Falla 1, Majadahonda, 28222, Madrid, Spain. .
Cobo M; Hospital Regional Universitario de Málaga, Málaga, Spain.
Rodriguez-Abreu D; Hospital Universitario Insular de Gran Canaria, Las Palmas de Gran Canaria, Spain.
Calvo V; Medical Oncology Department, Hospital Universitario Puerta de Hierro-Majadahonda, C/ Manuel de Falla 1, Majadahonda, 28222, Madrid, Spain.
Carcereny E; Catalan Institute of Oncology, Hospital Universitari Germans Trias i Pujol, B-ARGO, IGTP, Badalona, Spain.
Cantero A; Hospital Regional Universitario de Málaga, Málaga, Spain.
Bernabé R; Hospital Universitario Virgen del Rocio, Sevilla, Spain.
Benitez G; Hospital Universitario Insular de Gran Canaria, Las Palmas de Gran Canaria, Spain.
Castro RL; Hospital Clínico Universitario de Valladolid, Valladolid, Spain.
Massutí B; Hospital General Universitario de Alicante, Alicante, Spain.
Del Barco E; Hospital Universitario de Salamanca, Salamanca, Spain.
García Campelo R; Complejo Hospitalario Universitario A Coruña, A Coruña, Spain.
Guirado M; Hospital General Universitario de Elche, Elche, Spain.
Camps C; Hospital General Universitario de Valencia, Valencia, Spain.; Universidad de Valencia, Valencia, Spain.; CIBERONC, Madrid, Spain.
Ortega AL; Hospital Universitario de Jaén, Jaén, Spain.
González Larriba JL; Hospital Universitario Clínico San Carlos, Madrid, Spain.
Sánchez A; Hospital Provincial de Castellón, Castellón, Spain.
Casal J; Complexo Hospitalario de Vigo, Vigo, Spain.
Sala MA; OSI Bilbao Basurto, Bibao, Spain.
Juan-Vidal O; Hospital Universitario y Politécnico La Fe, Valencia, Spain.
Bosch-Barrera J; Catalan Institute of Oncology, Hospital Universitari Dr. Josep Trueta, Girona, Spain.
Oramas J; Hospital Universitario de Canarias, Santa Cruz de Tenerife, Spain.
Dómine M; Hospital Universitario Fundación Jiménez Díaz. IIS-FJD, Madrid, Spain.
Trigo JM; Hospital Universitario Virgen de la Victoria, Málaga, Spain.
Blanco R; Consorci Sanitari de Terrassa, Barcelona, Spain.
Calzas J; Hospital Universitario de Fuenlabrada, Fuenlabrada, Spain.
Morilla I; Complejo Hospitalario de Navarra, Navarra, Spain.
Padilla A; Hospital Universitario Nuestra Señora de la Candelaria, Santa Cruz de Tenerife, Spain.
Pimentao J; Department of Electrical Engineering, NOVA School of Science and Technology, Universidade Nova de Lisboa, Lisbon, Portugal.
Sousa PA; Department of Electrical Engineering, NOVA School of Science and Technology, Universidade Nova de Lisboa, Lisbon, Portugal.
Torrente M; Medical Oncology Department, Hospital Universitario Puerta de Hierro-Majadahonda, C/ Manuel de Falla 1, Majadahonda, 28222, Madrid, Spain.
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Źródło:
BMC cancer [BMC Cancer] 2022 Jul 05; Vol. 22 (1), pp. 732. Date of Electronic Publication: 2022 Jul 05.
Typ publikacji:
Journal Article; Observational Study
MeSH Terms:
Carcinoma, Non-Small-Cell Lung*/diagnosis
Carcinoma, Non-Small-Cell Lung*/epidemiology
Carcinoma, Non-Small-Cell Lung*/therapy
Lung Neoplasms*/diagnosis
Lung Neoplasms*/epidemiology
Lung Neoplasms*/therapy
Biomarkers, Tumor/analysis ; Demography ; ErbB Receptors/genetics ; ErbB Receptors/therapeutic use ; Humans ; Prospective Studies ; Protein-Tyrosine Kinases ; Proto-Oncogene Proteins ; Receptor Protein-Tyrosine Kinases ; Spain/epidemiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
LungBEAM: A prospective multicenter study to monitor stage IV NSCLC patients with EGFR mutations using BEAMing technology.
Autorzy:
Garrido P; Medical Oncology Department, IRYCIS Hospital Universitario Ramón y Cajal, Universidad Alcalá, Madrid, Spain.; CIBERONC, Madrid, Spain.
Paz-Ares L; CIBERONC, Madrid, Spain.; Medical Oncology Department, Hospital Universitario 12 de Octubre and i+12 Research Institute, Madrid, Spain.; Lung Cancer Group, Clinical Research Program, Spanish National Cancer Research Center (CNIO), Madrid, Spain.; Complutense University, Madrid, Spain.
Majem M; Medical Oncology Department, Hospital De La Santa Creu I Sant Pau, Barcelona, Spain.; Spanish Lung Cancer Group (GECP), Barcelona, Spain.
Morán T; Spanish Lung Cancer Group (GECP), Barcelona, Spain.; ICO Badalona, Hospital Germans Trias i Pujol, Barcelona, Spain.
Trigo JM; Medical Oncology Department, Hospital Universitario Virgen de la Victoria, Málaga, Spain.
Bosch-Barrera J; Medical Oncology, Catalan Institute of Oncology (ICO), Dr. Josep Trueta Hospital of Girona, Girona, Spain.
Garcίa-Campelo R; Medical Oncology Department, Hospital Universitario Da Coruña, A Coruña, Spain.
González-Larriba JL; Medical Oncology Department, Hospital Universitario Clínico San Carlos, Madrid, Spain.
Sánchez-Torres JM; Medical Oncology Department, Hospital de la Princesa, Madrid, Spain.
Isla D; Medical Oncology Department, Hospital Universitario Lozano Blesa, Zaragoza, Spain.
Viñolas N; Medical Oncology Department, Hospital Clinic i Provincial, Barcelona, Spain.
Camps C; CIBERONC, Madrid, Spain.; Medical Oncology Department, Hospital General Universitario de Valencia, Universidad de Valencia, Valencia, Spain.
Insa A; Medical Oncology Department, Hospital Clínico Universitario, Valencia, Spain.
Juan Ó; Medical Oncology Department, Hospital Universitario La Fe, Valencia, Spain.
Massuti B; Medical Oncology Department, Hospital General Universitario de Alicante, Alicante, Spain.
Paredes A; Medical Oncology Department, Hospital Universitario Donostia, Donostia-San Sebastián, Spain.
Artal Á; Medical Oncology, Hospital Universitario Miguel Servet, Zaragoza, Spain.
López-Brea M; Medical Oncology Department, Hospital Universitario Marqués de Valdecilla, Santander, Spain.
Palacios J; CIBERONC, Madrid, Spain.; Pathology Department, IRYCIS Hospital Universitario Ramón y Cajal, Universidad Alcalá, Madrid, Spain.
Felip E; Medical Oncology Department, Hospital Universitario Vall d'Hebron, Barcelona, Spain.
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Źródło:
Cancer medicine [Cancer Med] 2021 Sep; Vol. 10 (17), pp. 5878-5888. Date of Electronic Publication: 2021 Jul 23.
Typ publikacji:
Clinical Trial, Phase IV; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
MeSH Terms:
Carcinoma, Non-Small-Cell Lung/*genetics
Lung Neoplasms/*genetics
Aged ; Carcinoma, Non-Small-Cell Lung/pathology ; ErbB Receptors/metabolism ; Female ; Humans ; Lung Neoplasms/pathology ; Male ; Mutation ; Prospective Studies
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Epidemiology, treatment, and survival in small cell lung cancer in Spain: Data from the Thoracic Tumor Registry.
Autorzy:
Franco F; Hospital Universitario Puerta de Hierro-Majadahonda, Madrid, Spain.
Carcereny E; Catalan Institute of Oncology, Hospital Universitari Germans Trias i Pujol, B-ARGO, IGTP, Badalona, Spain.
Guirado M; Hospital General Universitario de Elche, Elche, Spain.
Ortega AL; Hospital Universitario de Jaén, Jaén, Spain.
López-Castro R; Hospital Clínico Universitario de Valladolid, Valladolid, Spain.
Rodríguez-Abreu D; Hospital Universitario Insular de Gran Canaria, Las Palmas de Gran Canaria, Spain.
García-Campelo R; Complejo Hospitalario Universitario A Coruña, A Coruña, Spain.
Del Barco E; Hospital Universitario de Salamanca, Salamanca, Spain.
Juan O; Hospital Universitario y Politécnico La Fe, Valencia, Spain.
Aparisi F; Hospital General de Valencia, Valencia, Spain.
González-Larriba JL; Hospital Universitario Clínico San Carlos, Madrid, Spain.
Domine M; Hospital Universitario Fundación Jiménez Díaz, IIS-FJD, Madrid, Spain.
Trigo JM; Unidad de Gestión Clínica Intercentros de Oncología Médica, Hospitales Universitarios Regional y Virgen de la Victoria, IBIMA, Málaga, Spain.
Cobo M; Unidad de Gestión Clínica Intercentros de Oncología Médica, Hospitales Universitarios Regional y Virgen de la Victoria, IBIMA, Málaga, Spain.
Cerezo S; Hospital General La Mancha Centro, Alcázar de San Juan, Spain.
Calzas J; Hospital Universitario de Fuenlabrada, Fuenlabrada, Spain.
Massutí B; Hospital General Universitario de Alicante, Alicante, Spain.
Bosch-Barrera J; Catalan Institute of Oncology, Girona, Spain.
García Coves P; Hospital General Universitario de Elche, Elche, Spain.
Domènech M; Catalan Institute of Oncology, Hospital Universitari Germans Trias i Pujol, B-ARGO, IGTP, Badalona, Spain.
Provencio M; Hospital Universitario Puerta de Hierro-Majadahonda, Madrid, Spain.
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Źródło:
PloS one [PLoS One] 2021 Jun 02; Vol. 16 (6), pp. e0251761. Date of Electronic Publication: 2021 Jun 02 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Lung Neoplasms/*mortality
Registries/*statistics & numerical data
Small Cell Lung Carcinoma/*mortality
Aged ; Combined Modality Therapy ; Female ; Follow-Up Studies ; Humans ; Lung Neoplasms/epidemiology ; Lung Neoplasms/pathology ; Lung Neoplasms/therapy ; Male ; Middle Aged ; Prognosis ; Retrospective Studies ; Small Cell Lung Carcinoma/epidemiology ; Small Cell Lung Carcinoma/secondary ; Small Cell Lung Carcinoma/therapy ; Spain/epidemiology ; Survival Rate
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Causes of death in patients with locally advanced head and neck cancer treated with radiotherapy and systemic therapy.
Autorzy:
Zapata I; Radiation Oncology Department, Hospital Universitario Virgen de la Victoria, Campus Teatinos s/n., 29010, Malaga, Spain.
Alvarez M; Laboratorio de biología molecular del cancer, centro de investigaciones medico-sanitarias (CIMES), Universidad de Málaga, Malaga, Spain.; Instituto de investigación biomédica de Malaga, Campus Teatinos s/n., 29010, Malaga, Spain.; Pathology Department, Hospital Universitario Virgen de la Victoria, Campus Teatinos s/n., 29010, Malaga, Spain.
Hidalgo R; Servicio central de Informatica, Universidad de Malaga, Malaga, Spain.
Pajares B; Medical Oncology Department, Hospital Universitario Virgen de la Victoria, Campus Teatinos s/n, 29010, Malaga, Spain.
Garcia-Anaya MJ; Radiation Oncology Department, Hospital Universitario Virgen de la Victoria, Campus Teatinos s/n., 29010, Malaga, Spain.
Toledo MD; Radiation Oncology Department, Hospital Universitario Virgen de la Victoria, Campus Teatinos s/n., 29010, Malaga, Spain.
Trigo JM; Medical Oncology Department, Hospital Universitario Virgen de la Victoria, Campus Teatinos s/n, 29010, Malaga, Spain.
Lupiañez-Perez Y; Radiation Oncology Department, Hospital Universitario Virgen de la Victoria, Campus Teatinos s/n., 29010, Malaga, Spain.
Medina JA; Radiation Oncology Department, Hospital Universitario Virgen de la Victoria, Campus Teatinos s/n., 29010, Malaga, Spain.
Jaime Gomez-Millan J; Radiation Oncology Department, Hospital Universitario Virgen de la Victoria, Campus Teatinos s/n., 29010, Malaga, Spain. .; Instituto de investigación biomédica de Malaga, Campus Teatinos s/n., 29010, Malaga, Spain. .
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Źródło:
BMC cancer [BMC Cancer] 2019 Dec 21; Vol. 19 (1), pp. 1241. Date of Electronic Publication: 2019 Dec 21.
Typ publikacji:
Journal Article
MeSH Terms:
Cause of Death*
Antineoplastic Combined Chemotherapy Protocols/*therapeutic use
Neoplasm Recurrence, Local/*mortality
Neoplasm Recurrence, Local/*therapy
Adult ; Age Factors ; Aged ; Aged, 80 and over ; Chemoradiotherapy/mortality ; Comorbidity ; Female ; Head and Neck Neoplasms/drug therapy ; Head and Neck Neoplasms/epidemiology ; Head and Neck Neoplasms/radiotherapy ; Head and Neck Neoplasms/therapy ; Humans ; Male ; Middle Aged ; Neoplasm Recurrence, Local/drug therapy ; Neoplasm Recurrence, Local/radiotherapy ; Retrospective Studies ; Spain/epidemiology ; Survival Rate
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Nabiximols combined with motivational enhancement/cognitive behavioral therapy for the treatment of cannabis dependence: A pilot randomized clinical trial.
Autorzy:
Trigo JM; Translational Addiction Research Laboratory, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health (CAMH), Toronto, Canada.
Soliman A; Translational Addiction Research Laboratory, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health (CAMH), Toronto, Canada.
Quilty LC; Campbell Family Mental Health Research Institute, CAMH, Toronto, Canada.; Department of Psychiatry, University of Toronto, Toronto, Canada.
Fischer B; Department of Psychiatry, University of Toronto, Toronto, Canada.; Institute of Medical Science, University of Toronto, Faculty of Medicine, Toronto, Canada.; Institute for Mental Health Policy Research, CAMH, Toronto, Canada.; Centre for Applied Research in Mental Health & Addiction, Faculty of Health Sciences, Simon Fraser University, Vancouver, Canada.
Rehm J; Department of Psychiatry, University of Toronto, Toronto, Canada.; Institute of Medical Science, University of Toronto, Faculty of Medicine, Toronto, Canada.; Institute for Mental Health Policy Research, CAMH, Toronto, Canada.; Addiction Policy, Dalla Lana School of Public Health, University of Toronto, Toronto, Canada.; Institute of Clinical Psychology and Psychotherapy & Center of Clinical Epidemiology and Longitudinal Studies (CELOS), Technische Universität Dresden, Dresden, Germany.
Selby P; Department of Psychiatry, University of Toronto, Toronto, Canada.; Addictions Division, CAMH, Toronto, Canada.; Department of Family and Community Medicine, University of Toronto, Toronto, Canada.
Barnes AJ; Chemistry and Drug Metabolism, National Institute on Drug Abuse (NIDA), National Institutes of Health (NIH), Baltimore, United States of America.
Huestis MA; Chemistry and Drug Metabolism, National Institute on Drug Abuse (NIDA), National Institutes of Health (NIH), Baltimore, United States of America.
George TP; Department of Psychiatry, University of Toronto, Toronto, Canada.; Addictions Division, CAMH, Toronto, Canada.; Division of Brain and Therapeutics, CAMH, Toronto, Canada.
Streiner DL; Department of Psychiatry, University of Toronto, Toronto, Canada.; Department of Psychiatry & Behavioural Neurosciences, McMaster University, Hamilton, Canada.
Staios G; Translational Addiction Research Laboratory, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health (CAMH), Toronto, Canada.
Le Foll B; Translational Addiction Research Laboratory, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health (CAMH), Toronto, Canada.; Addictions Division, CAMH, Toronto, Canada.
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Źródło:
PloS one [PLoS One] 2018 Jan 31; Vol. 13 (1), pp. e0190768. Date of Electronic Publication: 2018 Jan 31 (Print Publication: 2018).
Typ publikacji:
Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural
MeSH Terms:
Cognitive Behavioral Therapy*
Motivation*
Cannabidiol/*therapeutic use
Dronabinol/*therapeutic use
Marijuana Abuse/*therapy
Adult ; Craving ; Double-Blind Method ; Drug Combinations ; Female ; Humans ; Male ; Middle Aged ; Pilot Projects ; Placebos ; Substance Withdrawal Syndrome/therapy ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Subcellular localisation of pMEK has a different prognosis in locally advanced head and neck cancer treated with concomitant radiochemotherapy.
Autorzy:
Gomez-Millan J; Radiation Oncology Department, Hospital Universitario Virgen de la Victoria, Campus Teatinos s/n, 29010, Malaga, Spain. .
Pajares B; Medical Oncology Department, Hospital Universitario Virgen de la Victoria, Campus Teatinos s/n, 29010, Malaga, Spain. .
Perez-Villa L; Pathology Department, Hospital Universitario Virgen de la Victoria, Campus Teatinos s/n, 29010, Malaga, Spain.
Carnero A; Instituto de Biomedicina de Sevilla (IBIS), Consejo superior de investigaciones científicas, Campus Universitario Virgen del Rocío, Avda, Manuel Siurot s/n, 41013, Sevilla, Spain.
Alvarez M; Pathology Department, Facultad de Medicina, UMA, Campus Teatinos s/n, 29010, Malaga, Spain.
De Luque V; Medical Oncology Department, Hospital Universitario Virgen de la Victoria, Campus Teatinos s/n, 29010, Malaga, Spain.
Rivas F; Agencia Sanitaria Costa del Sol, Unidad de Investigación, Autovia A-7, Km 187, 29063, Marbella, Málaga, Spain.; Red Nacional de Investigación de Servicios de Salud en Enfermedades crónicas (REDISSEC), Madrid, Spain.
Trigo JM; Medical Oncology Department, Hospital Universitario Virgen de la Victoria, Campus Teatinos s/n, 29010, Malaga, Spain.
Toledo MD; Radiation Oncology Department, Hospital Universitario Virgen de la Victoria, Campus Teatinos s/n, 29010, Malaga, Spain.
Alba E; Medical Oncology Department, Hospital Universitario Virgen de la Victoria, Campus Teatinos s/n, 29010, Malaga, Spain.
Medina JA; Radiation Oncology Department, Hospital Universitario Virgen de la Victoria, Campus Teatinos s/n, 29010, Malaga, Spain.
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Źródło:
BMC cancer [BMC Cancer] 2016 Oct 28; Vol. 16 (1), pp. 829. Date of Electronic Publication: 2016 Oct 28.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Extracellular Signal-Regulated MAP Kinases/*metabolism
Head and Neck Neoplasms/*metabolism
Head and Neck Neoplasms/*mortality
Adult ; Aged ; Biomarkers ; Chemoradiotherapy ; Extracellular Signal-Regulated MAP Kinases/genetics ; Female ; Gene Expression ; Head and Neck Neoplasms/pathology ; Head and Neck Neoplasms/therapy ; Humans ; Immunohistochemistry ; Kaplan-Meier Estimate ; Male ; Middle Aged ; Neoplasm Staging ; Phosphorylation ; Prognosis ; Protein Transport ; Risk Factors ; Signal Transduction
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Inhibition of monoacylglycerol lipase (MAGL) enhances cue-induced reinstatement of nicotine-seeking behavior in mice.
Autorzy:
Trigo JM; Translational Addiction Research Laboratory, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health (CAMH), 33 Russell Street, Toronto, ON, M5S 2S1, Canada.
Le Foll B; Translational Addiction Research Laboratory, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health (CAMH), 33 Russell Street, Toronto, ON, M5S 2S1, Canada. .; Addictions Division, CAMH, Toronto, ON, Canada. .; Alcohol Research and Treatment Clinic, Addiction Medicine Services, Ambulatory Care and Structured Treatments, Centre for Addiction and Mental Health, Toronto, ON, Canada. .; Department of Family and Community Medicine, University of Toronto, Toronto, ON, Canada. .; Department of Pharmacology, University of Toronto, Toronto, ON, Canada. .; Department of Psychiatry, Division of Brain and Therapeutics, University of Toronto, Toronto, ON, Canada. .; Institute of Medical Sciences, University of Toronto, Toronto, ON, Canada. .
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Źródło:
Psychopharmacology [Psychopharmacology (Berl)] 2016 May; Vol. 233 (10), pp. 1815-22. Date of Electronic Publication: 2015 Oct 22.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Benzodioxoles/*pharmacology
Drug-Seeking Behavior/*drug effects
Monoacylglycerol Lipases/*antagonists & inhibitors
Nicotine/*administration & dosage
Piperidines/*pharmacology
Animals ; Cues ; Drug-Seeking Behavior/physiology ; Glycerides/pharmacology ; Male ; Mice ; Mice, Inbred C57BL ; Reinforcement, Psychology ; Self Administration
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Phase I dose-finding study of cabazitaxel administered weekly in patients with advanced solid tumours.
Autorzy:
Fumoleau P; Centre Georges-François Leclerc, 1 rue Professeur Marion, 21079 Dijon Cedex France. .
Trigo JM
Isambert N
Sémiond D
Gupta S
Campone M
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Źródło:
BMC cancer [BMC Cancer] 2013 Oct 07; Vol. 13, pp. 460. Date of Electronic Publication: 2013 Oct 07.
Typ publikacji:
Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antineoplastic Agents, Phytogenic/*therapeutic use
Neoplasms/*drug therapy
Neoplasms/*pathology
Taxoids/*therapeutic use
Adult ; Aged ; Antineoplastic Agents, Phytogenic/pharmacology ; Combined Modality Therapy ; Female ; Humans ; Male ; Maximum Tolerated Dose ; Middle Aged ; Neoplasm Staging ; Neoplasms/diagnosis ; Taxoids/pharmacology ; Treatment Outcome
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Phase I/II trial of cilengitide with cetuximab, cisplatin and 5-fluorouracil in recurrent and/or metastatic squamous cell cancer of the head and neck: findings of the phase I part.
Autorzy:
Vermorken JB; Department of Medical Oncology, Antwerp University Hospital, Wilrijkstraat 10, Edegem 2650, Belgium. />Guigay J
Mesia R
Trigo JM
Keilholz U
Kerber A
Bethe U
Picard M
Brummendorf TH
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Źródło:
British journal of cancer [Br J Cancer] 2011 May 24; Vol. 104 (11), pp. 1691-6. Date of Electronic Publication: 2011 May 03.
Typ publikacji:
Clinical Trial, Phase I; Clinical Trial, Phase II; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
MeSH Terms:
Antibodies, Monoclonal/*administration & dosage
Antineoplastic Combined Chemotherapy Protocols/*therapeutic use
Aged ; Antibodies, Monoclonal/adverse effects ; Antibodies, Monoclonal, Humanized ; Carcinoma/drug therapy ; Carcinoma/pathology ; Carcinoma, Squamous Cell ; Cetuximab ; Cisplatin/administration & dosage ; Female ; Fluorouracil/administration & dosage ; Head and Neck Neoplasms/drug therapy ; Head and Neck Neoplasms/pathology ; Humans ; Male ; Middle Aged ; Neoplasm Metastasis/drug therapy ; Neoplasm Recurrence, Local/drug therapy ; Neoplasms, Squamous Cell/drug therapy ; Neoplasms, Squamous Cell/pathology ; Squamous Cell Carcinoma of Head and Neck
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Attenuated behavioural responses to acute and chronic cocaine in GASP-1-deficient mice.
Autorzy:
Boeuf J; Institut de Recherche de l'ESBS, Centre National de la Recherche Scientifique, Université de Strasbourg, Illkirch, France.
Trigo JM
Moreau PH
Lecourtier L
Vogel E
Cassel JC
Mathis C
Klosen P
Maldonado R
Simonin F
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Źródło:
The European journal of neuroscience [Eur J Neurosci] 2009 Sep; Vol. 30 (5), pp. 860-8. Date of Electronic Publication: 2009 Aug 27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cocaine/*pharmacology
Exploratory Behavior/*drug effects
Receptors, G-Protein-Coupled/*physiology
Stereotyped Behavior/*drug effects
Analysis of Variance ; Animals ; Blotting, Western ; Cocaine/administration & dosage ; Corpus Striatum/metabolism ; Dopamine Uptake Inhibitors/administration & dosage ; Dopamine Uptake Inhibitors/pharmacology ; Intracellular Signaling Peptides and Proteins ; Mice ; Mice, Knockout ; Motor Activity/drug effects ; Motor Activity/physiology ; Radioligand Assay ; Receptors, Dopamine/metabolism ; Receptors, G-Protein-Coupled/genetics ; Receptors, Muscarinic/metabolism ; Self Administration ; Stereotyped Behavior/physiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
MDMA modifies active avoidance learning and recall in mice.
Autorzy:
Trigo JM; Laboratori de Neurofarmacologia, Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, Barcelona, Spain.
Cabrero-Castel A
Berrendero F
Maldonado R
Robledo P
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Źródło:
Psychopharmacology [Psychopharmacology (Berl)] 2008 Apr; Vol. 197 (3), pp. 391-400. Date of Electronic Publication: 2008 Jan 10.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Adrenergic Uptake Inhibitors/*pharmacology
Avoidance Learning/*drug effects
Conditioning, Classical/*drug effects
Mental Recall/*drug effects
N-Methyl-3,4-methylenedioxyamphetamine/*pharmacology
Animals ; Association Learning/drug effects ; Corpus Striatum/drug effects ; Dopamine Plasma Membrane Transport Proteins/drug effects ; Dose-Response Relationship, Drug ; Drug Administration Schedule ; Fear/drug effects ; Male ; Mice ; Retention, Psychology/drug effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
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