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Wyszukujesz frazę ""Tripartite Motif-Containing Protein 28"" wg kryterium: Temat


Tytuł :
TRIM28 functions as the SUMO E3 ligase for PCNA in prevention of transcription induced DNA breaks.
Autorzy :
Li M; Department of Cancer Genetics and Epigenetics, Beckman Research Institute, City of Hope, Duarte, CA 91010-3000.
Xu X; Department of Cancer Genetics and Epigenetics, Beckman Research Institute, City of Hope, Duarte, CA 91010-3000.
Chang CW; Department of Cancer Genetics and Epigenetics, Beckman Research Institute, City of Hope, Duarte, CA 91010-3000.
Liu Y; Department of Cancer Genetics and Epigenetics, Beckman Research Institute, City of Hope, Duarte, CA 91010-3000 .
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Sep 22; Vol. 117 (38), pp. 23588-23596. Date of Electronic Publication: 2020 Sep 08.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
DNA Replication/*genetics
Proliferating Cell Nuclear Antigen/*metabolism
Small Ubiquitin-Related Modifier Proteins/*metabolism
Tripartite Motif-Containing Protein 28/*metabolism
Ubiquitin-Protein Ligases/*metabolism
DNA Breaks ; HEK293 Cells ; Humans ; Proliferating Cell Nuclear Antigen/genetics ; RecQ Helicases/genetics ; RecQ Helicases/metabolism ; Small Ubiquitin-Related Modifier Proteins/genetics ; Tripartite Motif-Containing Protein 28/genetics ; Ubiquitin-Protein Ligases/genetics
Czasopismo naukowe
Tytuł :
KAP1 Is a Chromatin Reader that Couples Steps of RNA Polymerase II Transcription to Sustain Oncogenic Programs.
Autorzy :
Bacon CW; Department of Microbiology, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Biological Chemistry Graduate Program, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Challa A; Department of Microbiology, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Hyder U; Department of Microbiology, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Shukla A; Department of Microbiology, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Borkar AN; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK.
Bayo J; Instituto de Investigaciones en Medicina Traslacional, Facultad de Ciencias Biomédicas, CONICET, Universidad Austral, Derqui-Pilar, Buenos Aires 1629, Argentina.
Liu J; Department of Pharmacology, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Wu SY; Harold C. Simmons Comprehensive Cancer Center, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Department of Biochemistry, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Chiang CM; Harold C. Simmons Comprehensive Cancer Center, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Department of Biochemistry, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Department of Pharmacology, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Kutateladze TG; Department of Pharmacology, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
D'Orso I; Department of Microbiology, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. Electronic address: .
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Źródło :
Molecular cell [Mol Cell] 2020 Jun 18; Vol. 78 (6), pp. 1133-1151.e14. Date of Electronic Publication: 2020 May 12.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
RNA Polymerase II/*metabolism
Tripartite Motif-Containing Protein 28/*metabolism
Acetylation ; Cell Line, Tumor ; Chromatin/genetics ; Chromatin/metabolism ; Cyclin-Dependent Kinase 9/metabolism ; Gene Expression Regulation/genetics ; Histones/metabolism ; Humans ; Oncogenes/genetics ; Promoter Regions, Genetic/genetics ; Protein Processing, Post-Translational/genetics ; RNA Polymerase II/genetics ; Smad2 Protein/metabolism ; Transcription Factors/metabolism ; Transcription, Genetic ; Tripartite Motif-Containing Protein 28/genetics
Czasopismo naukowe
Tytuł :
Hdac3, Setdb1, and Kap1 mark H3K9me3/H3K14ac bivalent regions in young and aged liver.
Autorzy :
Price AJ; Department of Pharmacology, University of Virginia, Charlottesville, VA, USA.
Manjegowda MC; Department of Pharmacology, University of Virginia, Charlottesville, VA, USA.
Kain J; Department of Pharmacology, University of Virginia, Charlottesville, VA, USA.
Anandh S; Department of Pharmacology, University of Virginia, Charlottesville, VA, USA.
Bochkis IM; Department of Pharmacology, University of Virginia, Charlottesville, VA, USA.
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Źródło :
Aging cell [Aging Cell] 2020 Feb; Vol. 19 (2), pp. e13092. Date of Electronic Publication: 2019 Dec 19.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Aging/*metabolism
Chromatin/*metabolism
Histone Deacetylases/*metabolism
Histone-Lysine N-Methyltransferase/*metabolism
Histones/*metabolism
Liver/*metabolism
Tripartite Motif-Containing Protein 28/*metabolism
Acetylation ; Aging/physiology ; Animals ; Chromatin/physiology ; Chromatin Immunoprecipitation Sequencing ; Histone Deacetylases/genetics ; Histone-Lysine N-Methyltransferase/genetics ; Lipid Metabolism ; Liver/physiology ; Male ; Mass Spectrometry ; Methylation ; Mice ; Mice, Inbred C57BL ; Nucleosomes/metabolism ; Protein Processing, Post-Translational ; Proteome/genetics ; Proteome/metabolism ; Tripartite Motif-Containing Protein 28/genetics
Czasopismo naukowe
Tytuł :
Critical role for TRIM28 and HP1β/γ in the epigenetic control of T cell metabolic reprograming and effector differentiation.
Autorzy :
Gehrmann U; Institut Curie, Université Paris Sciences et Lettres, INSERM U932, 75005 Paris, France; .; Translational Science and Experimental Medicine, Research and Early Development, Respiratory, Inflammation and Autoimmunity, BioPharmaceuticals Research and Development, AstraZeneca, Gothenburg, 431 83 Mölndal, Sweden.
Burbage M; Institut Curie, Université Paris Sciences et Lettres, INSERM U932, 75005 Paris, France.
Zueva E; Institut Curie, Université Paris Sciences et Lettres, INSERM U932, 75005 Paris, France.
Goudot C; Institut Curie, Université Paris Sciences et Lettres, INSERM U932, 75005 Paris, France.
Esnault C; Institute de Génétique Moléculaire de Montpellier, University of Montpellier, CNRS, 34094 Montpellier, France.
Ye M; Institut Curie, Université Paris Sciences et Lettres, INSERM U932, 75005 Paris, France.
Carpier JM; Institut Curie, Université Paris Sciences et Lettres, INSERM U932, 75005 Paris, France.
Burgdorf N; Institut Curie, Université Paris Sciences et Lettres, INSERM U932, 75005 Paris, France.
Hoyler T; Institut Curie, Université Paris Sciences et Lettres, INSERM U932, 75005 Paris, France.
Suarez G; Institut Curie, Université Paris Sciences et Lettres, INSERM U932, 75005 Paris, France.
Joannas L; Institut Curie, Université Paris Sciences et Lettres, INSERM U932, 75005 Paris, France.
Heurtebise-Chrétien S; Institut Curie, Université Paris Sciences et Lettres, INSERM U932, 75005 Paris, France.
Durand S; Institut Gustave Roussy, Plateforme Métabolomique/UMR1138, 94800 Villejuif, France.; Equipe Labellisée par la Ligue contre le Cancer, Université de Paris, Sorbonne Université, INSERM U1138, Centre de Recherche des Cordeliers, 75006 Paris, France.
Panes R; Faculté de Médecine, Département de Microbiologie, Infectiologie et Immunologie, Université de Montréal, Montréal, QC H3T 1J4, Canada.; Axe de Recherche en Immunobiologie du Cancer, Institut de Recherche en Immunologie et Cancérologie, Montréal, QC H3T 1J4, Canada.
Bellemare-Pelletier A; Axe de Recherche en Immunobiologie du Cancer, Institut de Recherche en Immunologie et Cancérologie, Montréal, QC H3T 1J4, Canada.
Sáez PJ; Institut Curie, Université Paris Sciences et Lettres, INSERM U932, 75005 Paris, France.
Aprahamian F; Institut Gustave Roussy, Plateforme Métabolomique/UMR1138, 94800 Villejuif, France.; Equipe Labellisée par la Ligue contre le Cancer, Université de Paris, Sorbonne Université, INSERM U1138, Centre de Recherche des Cordeliers, 75006 Paris, France.
Lefevre D; Institut Gustave Roussy, Plateforme Métabolomique/UMR1138, 94800 Villejuif, France.; Equipe Labellisée par la Ligue contre le Cancer, Université de Paris, Sorbonne Université, INSERM U1138, Centre de Recherche des Cordeliers, 75006 Paris, France.
Adoue V; CNRS, Centre de Physiopathologie de Toulouse Purpan, Université de Toulouse, Université Paul Sabatier, 31330 Toulouse, France.
Zine El Aabidine A; Institute de Génétique Moléculaire de Montpellier, University of Montpellier, CNRS, 34094 Montpellier, France.
Muhammad Ahmad M; Institute de Génétique Moléculaire de Montpellier, University of Montpellier, CNRS, 34094 Montpellier, France.
Hivroz C; Institut Curie, Université Paris Sciences et Lettres, INSERM U932, 75005 Paris, France.
Joffre O; INSERM U1043, Centre de Physiopathologie de Toulouse Purpan, Université de Toulouse, Université Paul Sabatier, 31330 Toulouse, France.
Cammas F; Institut de Recherche en Cancérologie de Montpellier, INSERM U1194, Université Montpellier, 34298 Montpellier, France.; Institut Régional du Cancer Montpellier, Université Montpellier, 34298 Montpellier, France.
Kroemer G; Institut Gustave Roussy, Plateforme Métabolomique/UMR1138, 94800 Villejuif, France.; Equipe Labellisée par la Ligue contre le Cancer, Université de Paris, Sorbonne Université, INSERM U1138, Centre de Recherche des Cordeliers, 75006 Paris, France.; Pôle de Biologie, Hôpital Européen Georges Pompidou, Assistance Publique-Hôpitaux de Paris, 75015 Paris, France.; Suzhou Institute for Systems Medicine, Chinese Academy of Medical Sciences, Suzhou 215123, China.; Department of Women's and Children's Health, Karolinska University Hospital, Karolinska Institute, 17177 Stockholm, Sweden.
Gagnon E; Faculté de Médecine, Département de Microbiologie, Infectiologie et Immunologie, Université de Montréal, Montréal, QC H3T 1J4, Canada.; Axe de Recherche en Immunobiologie du Cancer, Institut de Recherche en Immunologie et Cancérologie, Montréal, QC H3T 1J4, Canada.
Andrau JC; Institute de Génétique Moléculaire de Montpellier, University of Montpellier, CNRS, 34094 Montpellier, France.
Amigorena S; Institut Curie, Université Paris Sciences et Lettres, INSERM U932, 75005 Paris, France; .
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2019 Dec 17; Vol. 116 (51), pp. 25839-25849. Date of Electronic Publication: 2019 Nov 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Differentiation/*physiology
Cellular Reprogramming/*physiology
Chromosomal Proteins, Non-Histone/*metabolism
Epigenesis, Genetic/*physiology
T-Lymphocytes/*metabolism
Tripartite Motif-Containing Protein 28/*metabolism
Animals ; Autoimmunity/physiology ; CD4-Positive T-Lymphocytes/metabolism ; Cell Differentiation/genetics ; Cell Plasticity/physiology ; Cellular Reprogramming/genetics ; Colon/pathology ; Cytokines/metabolism ; DNA-Binding Proteins/genetics ; DNA-Binding Proteins/metabolism ; Gene Expression Regulation ; Gene Silencing ; Histones/metabolism ; Mice ; Mice, Knockout ; Phosphatidylinositol 3-Kinases/metabolism ; Receptors, Antigen, T-Cell/metabolism ; T-Lymphocytes, Regulatory/immunology ; T-Lymphocytes, Regulatory/metabolism ; Transcriptome ; Tripartite Motif-Containing Protein 28/genetics
Czasopismo naukowe
Tytuł :
Genome-wide CRISPR knockout screen identifies ZNF304 as a silencer of HIV transcription that promotes viral latency.
Autorzy :
Krasnopolsky S; The Shraga Segal Department of Microbiology Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Kuzmina A; The Shraga Segal Department of Microbiology Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Taube R; The Shraga Segal Department of Microbiology Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
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Źródło :
PLoS pathogens [PLoS Pathog] 2020 Sep 21; Vol. 16 (9), pp. e1008834. Date of Electronic Publication: 2020 Sep 21 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation, Viral*
Gene Silencing*
Repressor Proteins*/genetics
Repressor Proteins*/metabolism
Transcription Factors*/genetics
Transcription Factors*/metabolism
Transcription, Genetic*
Virus Latency*
CD4-Positive T-Lymphocytes/*metabolism
HIV-1/*physiology
CD4-Positive T-Lymphocytes/virology ; CRISPR-Cas Systems ; Gene Knockout Techniques ; Genome-Wide Association Study ; Humans ; Jurkat Cells ; Promoter Regions, Genetic ; Tripartite Motif-Containing Protein 28/genetics ; Tripartite Motif-Containing Protein 28/metabolism
Czasopismo naukowe
Tytuł :
Knockdown of TRIM28 inhibits PDGF-BB-induced vascular smooth muscle cell proliferation and migration.
Autorzy :
Liu H; Department of Cardiovascular Medicine, Shenzhen Longhua District Central Hospital, Longhua Central Hospital Affiliated Guangdong Medical University, Shenzhen, 518110, Guangdong Province, China. Electronic address: .
Chen H; Department of Cardiovascular Medicine, Shenzhen Longhua District Central Hospital, Longhua Central Hospital Affiliated Guangdong Medical University, Shenzhen, 518110, Guangdong Province, China.
Deng X; Pharmacy Department, Shenzhen Longhua District Central Hospital, Longhua Central Hospital Affiliated Guangdong Medical University, Shenzhen, 518110, Guangdong Province, China.
Peng Y; Department of Institute of Cardiovascular Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, Hubei Province, China.
Zeng Q; Department of Institute of Cardiovascular Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, Hubei Province, China.
Song Z; Department of Cardiovascular Medicine, Shenzhen Longhua District Central Hospital, Longhua Central Hospital Affiliated Guangdong Medical University, Shenzhen, 518110, Guangdong Province, China.
He W; Department of Cardiovascular Medicine, Shenzhen Longhua District Central Hospital, Longhua Central Hospital Affiliated Guangdong Medical University, Shenzhen, 518110, Guangdong Province, China.
Zhang L; Department of Cardiovascular Medicine, Shenzhen Longhua District Central Hospital, Longhua Central Hospital Affiliated Guangdong Medical University, Shenzhen, 518110, Guangdong Province, China.
Xiao T; Department of Cardiovascular Medicine, Shenzhen Longhua District Central Hospital, Longhua Central Hospital Affiliated Guangdong Medical University, Shenzhen, 518110, Guangdong Province, China.
Gao G; Department of Cardiovascular Medicine, Shenzhen Longhua District Central Hospital, Longhua Central Hospital Affiliated Guangdong Medical University, Shenzhen, 518110, Guangdong Province, China.
Li B; Department of Cardiovascular Medicine, Shenzhen Longhua District Central Hospital, Longhua Central Hospital Affiliated Guangdong Medical University, Shenzhen, 518110, Guangdong Province, China.
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Źródło :
Chemico-biological interactions [Chem Biol Interact] 2019 Sep 25; Vol. 311, pp. 108772. Date of Electronic Publication: 2019 Jul 24.
Typ publikacji :
Journal Article
MeSH Terms :
Becaplermin/*pharmacology
Cell Proliferation/*drug effects
Tripartite Motif-Containing Protein 28/*metabolism
Atherosclerosis/metabolism ; Atherosclerosis/pathology ; Calcium-Binding Proteins/metabolism ; Cell Movement/drug effects ; Cells, Cultured ; Humans ; Microfilament Proteins/metabolism ; Myocytes, Smooth Muscle/cytology ; Myocytes, Smooth Muscle/drug effects ; Myocytes, Smooth Muscle/metabolism ; RNA Interference ; RNA, Small Interfering/metabolism ; Transcription Factor RelA/metabolism ; Tripartite Motif-Containing Protein 28/antagonists & inhibitors ; Tripartite Motif-Containing Protein 28/genetics ; Up-Regulation/drug effects
Czasopismo naukowe
Tytuł :
Expression and Significance of TRIM 28 in Squamous Carcinoma of Esophagus.
Autorzy :
Liu B; Department of Pathology, First Affiliated Hospital of Hebei North University, Zhangjiakou, 075000, China.
Li X; Department of Histology and Embryology, Hebei North University, 11 Zuanshi South Road, Zhangjiakou, 075000, Hebei, China.
Liu F; Department of Histology and Embryology, Hebei North University, 11 Zuanshi South Road, Zhangjiakou, 075000, Hebei, China.
Li F; Department of Oncology, No.251 Hospital of the Chinese People's Liberation Army, Zhangjiakou, 075000, China.
Wei S; Department of Oncology, No.251 Hospital of the Chinese People's Liberation Army, Zhangjiakou, 075000, China.
Liu J; Department of Pathology, First Affiliated Hospital of Hebei North University, Zhangjiakou, 075000, China.
Lv Y; Department of Histology and Embryology, Hebei North University, 11 Zuanshi South Road, Zhangjiakou, 075000, Hebei, China. .
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Źródło :
Pathology oncology research : POR [Pathol Oncol Res] 2019 Oct; Vol. 25 (4), pp. 1645-1652. Date of Electronic Publication: 2018 Nov 27.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation, Neoplastic*
Biomarkers, Tumor/*metabolism
Carcinoma in Situ/*pathology
Esophageal Neoplasms/*pathology
Esophageal Squamous Cell Carcinoma/*secondary
Tripartite Motif-Containing Protein 28/*metabolism
Adult ; Aged ; Biomarkers, Tumor/genetics ; Carcinoma in Situ/genetics ; Carcinoma in Situ/metabolism ; Esophageal Neoplasms/genetics ; Esophageal Neoplasms/metabolism ; Esophageal Squamous Cell Carcinoma/genetics ; Esophageal Squamous Cell Carcinoma/metabolism ; Female ; Follow-Up Studies ; Humans ; Lymphatic Metastasis ; Male ; Middle Aged ; Neoplasm Invasiveness ; Prognosis ; Survival Rate ; Tripartite Motif-Containing Protein 28/genetics
Czasopismo naukowe
Tytuł :
Structure of KAP1 tripartite motif identifies molecular interfaces required for retroelement silencing.
Autorzy :
Stoll GA; Molecular Immunity Unit, Department of Medicine, University of Cambridge, Medical Research Council Laboratory of Molecular Biology (MRC-LMB), CB2 0QH Cambridge, United Kingdom.; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), Department of Medicine, University of Cambridge, CB2 0AW Cambridge, United Kingdom.
Oda SI; Molecular Immunity Unit, Department of Medicine, University of Cambridge, Medical Research Council Laboratory of Molecular Biology (MRC-LMB), CB2 0QH Cambridge, United Kingdom.; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), Department of Medicine, University of Cambridge, CB2 0AW Cambridge, United Kingdom.
Chong ZS; Molecular Immunity Unit, Department of Medicine, University of Cambridge, Medical Research Council Laboratory of Molecular Biology (MRC-LMB), CB2 0QH Cambridge, United Kingdom.; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), Department of Medicine, University of Cambridge, CB2 0AW Cambridge, United Kingdom.
Yu M; X-ray Crystallography Facility, MRC-LMB, CB2 0QH Cambridge, United Kingdom.
McLaughlin SH; Biophysics Facility, MRC-LMB, CB2 0QH Cambridge, United Kingdom.
Modis Y; Molecular Immunity Unit, Department of Medicine, University of Cambridge, Medical Research Council Laboratory of Molecular Biology (MRC-LMB), CB2 0QH Cambridge, United Kingdom; .; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), Department of Medicine, University of Cambridge, CB2 0AW Cambridge, United Kingdom.
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2019 Jul 23; Vol. 116 (30), pp. 15042-15051. Date of Electronic Publication: 2019 Jul 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Epigenesis, Genetic*
Gene Silencing*
Retroelements*
Repressor Proteins/*chemistry
Tripartite Motif-Containing Protein 28/*chemistry
Amino Acid Sequence ; Binding Sites ; Chromatin/chemistry ; Chromatin/metabolism ; Chromatin Assembly and Disassembly ; Cloning, Molecular ; Crystallography, X-Ray ; Escherichia coli/genetics ; Escherichia coli/metabolism ; Gene Expression ; Genetic Vectors/chemistry ; Genetic Vectors/metabolism ; Humans ; Models, Molecular ; Protein Binding ; Protein Conformation, alpha-Helical ; Protein Conformation, beta-Strand ; Protein Interaction Domains and Motifs ; Protein Multimerization ; Recombinant Proteins/chemistry ; Recombinant Proteins/genetics ; Recombinant Proteins/metabolism ; Repressor Proteins/genetics ; Repressor Proteins/metabolism ; Sequence Alignment ; Sequence Homology, Amino Acid ; Transcription, Genetic ; Tripartite Motif-Containing Protein 28/genetics ; Tripartite Motif-Containing Protein 28/metabolism
Czasopismo naukowe
Tytuł :
A Dissection of Oligomerization by the TRIM28 Tripartite Motif and the Interaction with Members of the Krab-ZFP Family.
Autorzy :
Sun Y; School of Biological Sciences, University of Auckland, Auckland, New Zealand.
Keown JR; School of Biological Sciences, University of Auckland, Auckland, New Zealand.
Black MM; School of Biological Sciences, University of Auckland, Auckland, New Zealand.
Raclot C; EPFL, Lausanne, Switzerland.
Demarais N; School of Biological Sciences, University of Auckland, Auckland, New Zealand.
Trono D; EPFL, Lausanne, Switzerland.
Turelli P; EPFL, Lausanne, Switzerland.
Goldstone DC; School of Biological Sciences, University of Auckland, Auckland, New Zealand. Electronic address: .
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Źródło :
Journal of molecular biology [J Mol Biol] 2019 Jun 28; Vol. 431 (14), pp. 2511-2527. Date of Electronic Publication: 2019 May 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Mutation*
Embryonic Stem Cells/*metabolism
Kruppel-Like Transcription Factors/*metabolism
Repressor Proteins/*metabolism
Tripartite Motif-Containing Protein 28/*metabolism
Animals ; Cells, Cultured ; Chromosomal Proteins, Non-Histone/genetics ; Chromosomal Proteins, Non-Histone/metabolism ; Embryonic Stem Cells/cytology ; Histone-Lysine N-Methyltransferase/genetics ; Histone-Lysine N-Methyltransferase/metabolism ; Humans ; Kruppel-Like Transcription Factors/chemistry ; Kruppel-Like Transcription Factors/genetics ; Mi-2 Nucleosome Remodeling and Deacetylase Complex/genetics ; Mi-2 Nucleosome Remodeling and Deacetylase Complex/metabolism ; Mice ; Molecular Dynamics Simulation ; Mutagenesis, Site-Directed ; Protein Binding ; Protein Conformation ; Protein Interaction Maps ; Protein Multimerization ; Repressor Proteins/chemistry ; Repressor Proteins/genetics ; Tripartite Motif-Containing Protein 28/chemistry ; Tripartite Motif-Containing Protein 28/genetics
Czasopismo naukowe
Tytuł :
KAP1 is an antiparallel dimer with a functional asymmetry.
Autorzy :
Fonti G; Institute of Bioengineering, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, Switzerland.
Marcaida MJ; Institute of Bioengineering, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland .; Swiss Institute of Bioinformatics, Lausanne, Switzerland.
Bryan LC; Institute of Chemical Sciences and Engineering, School of Basic Sciences, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Träger S; Institute of Bioengineering, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, Switzerland.
Kalantzi AS; Institute of Bioengineering, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, Switzerland.
Helleboid PJ; Global Health Institute, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Demurtas D; Interdisciplinary Centre for Electron Microscopy, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Tully MD; European Synchrotron Radiation Facility, Grenoble, France.
Grudinin S; University Grenoble Alpes, Centre National de la Recherche Scientifique, Inria, Grenoble Institut Polytechnique de Grenoble, Laboratoire Jean Kuntzmann, Grenoble, France.
Trono D; Global Health Institute, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Fierz B; Institute of Chemical Sciences and Engineering, School of Basic Sciences, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Dal Peraro M; Institute of Bioengineering, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland .; Swiss Institute of Bioinformatics, Lausanne, Switzerland.
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Źródło :
Life science alliance [Life Sci Alliance] 2019 Aug 19; Vol. 2 (4). Date of Electronic Publication: 2019 Aug 19 (Print Publication: 2019).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Tripartite Motif-Containing Protein 28/*metabolism
Binding Sites ; Cell Line ; Chromatin/genetics ; Chromatin/metabolism ; Heterochromatin/genetics ; Heterochromatin/metabolism ; Humans ; Promoter Regions, Genetic ; Sumoylation ; Transcription Factors/genetics ; Transcription Factors/metabolism ; Transcription, Genetic ; Tripartite Motif-Containing Protein 28/genetics
Czasopismo naukowe
Tytuł :
Methylation-directed glycosylation of chromatin factors represses retrotransposon promoters.
Autorzy :
Boulard M; Epigenetics and Neurobiology Unit, European Molecular Biology Laboratory (EMBL), 00015 Monterotondo, Italy; .
Rucli S; Epigenetics and Neurobiology Unit, European Molecular Biology Laboratory (EMBL), 00015 Monterotondo, Italy.; Joint PhD degree program, European Molecular Biology Laboratory and Faculty of Biosciences, Heidelberg University, 69117 Heidelberg, Germany.
Edwards JR; Center for Pharmacogenomics, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110; .
Bestor TH; Department of Genetics and Development, College of Physicians and Surgeons of Columbia University, New York, NY 10032 .
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Jun 23; Vol. 117 (25), pp. 14292-14298. Date of Electronic Publication: 2020 Jun 10.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Promoter Regions, Genetic*
Chromatin/*metabolism
Retroelements/*physiology
Tripartite Motif-Containing Protein 28/*metabolism
Acetylglucosamine/metabolism ; Animals ; DNA (Cytosine-5-)-Methyltransferase 1/genetics ; DNA (Cytosine-5-)-Methyltransferase 1/metabolism ; DNA Methylation ; Epigenesis, Genetic ; Gene Silencing ; Glycosylation ; Humans ; Methylation ; N-Acetylglucosaminyltransferases ; Nuclear Proteins/metabolism ; Protein Processing, Post-Translational ; Proteomics ; Repressor Proteins/metabolism ; Transcription Factors/metabolism
Czasopismo naukowe
Tytuł :
Anticancer drug and ionizing radiation-induced DNA damage differently influences transcription activity and DDR-related stress responses of an endothelial monolayer.
Autorzy :
Ziegler V; Institute of Toxicology, Medical Faculty, Heinrich Heine University, Duesseldorf, Moorenstrasse 5, 40225 Duesseldorf, Germany. Electronic address: .
Deußen M; Institute of Toxicology, Medical Faculty, Heinrich Heine University, Duesseldorf, Moorenstrasse 5, 40225 Duesseldorf, Germany. Electronic address: .
Schumacher L; Institute of Toxicology, Medical Faculty, Heinrich Heine University, Duesseldorf, Moorenstrasse 5, 40225 Duesseldorf, Germany. Electronic address: .
Roos WP; Institute of Toxicology, University Medical Center Mainz, Obere Zahlbacher Strasse 67, 55131 Mainz, Germany. Electronic address: .
Fritz G; Institute of Toxicology, Medical Faculty, Heinrich Heine University, Duesseldorf, Moorenstrasse 5, 40225 Duesseldorf, Germany. Electronic address: .
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Źródło :
Biochimica et biophysica acta. Molecular cell research [Biochim Biophys Acta Mol Cell Res] 2020 Jun; Vol. 1867 (6), pp. 118678. Date of Electronic Publication: 2020 Feb 14.
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antineoplastic Agents/*pharmacology
Ataxia Telangiectasia Mutated Proteins/*metabolism
Checkpoint Kinase 2/*metabolism
Cisplatin/*pharmacology
Tripartite Motif-Containing Protein 28/*metabolism
Tumor Suppressor Protein p53/*metabolism
Cell Survival/drug effects ; Cell Survival/radiation effects ; DNA Breaks, Double-Stranded ; Human Umbilical Vein Endothelial Cells ; Humans ; Phosphorylation/drug effects ; Phosphorylation/radiation effects ; Primary Cell Culture ; Radiation, Ionizing ; Signal Transduction/drug effects ; Signal Transduction/radiation effects ; Transcriptional Activation/drug effects ; Transcriptional Activation/radiation effects
Czasopismo naukowe
Tytuł :
TRIM28 and the control of transposable elements in the brain.
Autorzy :
Grassi DA; Laboratory of Molecular Neurogenetics, Department of Experimental Medical Science, Wallenberg Neuroscience Center and Lund Stem Cell Center, BMC A11, Lund University, 221 84 Lund, Sweden.
Jönsson ME; Laboratory of Molecular Neurogenetics, Department of Experimental Medical Science, Wallenberg Neuroscience Center and Lund Stem Cell Center, BMC A11, Lund University, 221 84 Lund, Sweden.
Brattås PL; Laboratory of Molecular Neurogenetics, Department of Experimental Medical Science, Wallenberg Neuroscience Center and Lund Stem Cell Center, BMC A11, Lund University, 221 84 Lund, Sweden.
Jakobsson J; Laboratory of Molecular Neurogenetics, Department of Experimental Medical Science, Wallenberg Neuroscience Center and Lund Stem Cell Center, BMC A11, Lund University, 221 84 Lund, Sweden. Electronic address: .
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Źródło :
Brain research [Brain Res] 2019 Feb 15; Vol. 1705, pp. 43-47. Date of Electronic Publication: 2018 Mar 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Brain/*metabolism
DNA Transposable Elements/*genetics
Tripartite Motif-Containing Protein 28/*genetics
Animals ; Epigenesis, Genetic/genetics ; Gene Expression Regulation/genetics ; Gene Regulatory Networks ; Humans ; Repressor Proteins/metabolism ; Transcription Factors/metabolism ; Tripartite Motif-Containing Protein 28/metabolism ; Tripartite Motif-Containing Protein 28/physiology
Czasopismo naukowe
Tytuł :
ATM Paradoxically Promotes Oncogenic Transformation via Transcriptional Reprogramming.
Autorzy :
Liu X; Department of Dermatology, Duke University Medical Center, Durham, North Carolina. .; School of Medicine, Sun Yat-Sen University, Guangzhou, China.
Hu M; Department of Dermatology, Duke University Medical Center, Durham, North Carolina.
Liu P; School of Medicine, Sun Yat-Sen University, Guangzhou, China.
Jiao M; Department of Dermatology, Duke University Medical Center, Durham, North Carolina.
Zhou M; Department of Dermatology, Duke University Medical Center, Durham, North Carolina.
Lee AK; Department of Dermatology, Duke University Medical Center, Durham, North Carolina.
Li F; Department of Dermatology, Duke University Medical Center, Durham, North Carolina.
Li CY; Department of Dermatology, Duke University Medical Center, Durham, North Carolina. .; Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina.; Duke Cancer Institute, Duke University Medical Center, Durham, North Carolina.
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Źródło :
Cancer research [Cancer Res] 2020 Apr 15; Vol. 80 (8), pp. 1669-1680. Date of Electronic Publication: 2020 Feb 14.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA Breaks, Double-Stranded*
Ataxia Telangiectasia Mutated Proteins/*genetics
Cell Transformation, Neoplastic/*genetics
Cellular Reprogramming/*genetics
DNA Repair/*physiology
Neoplastic Stem Cells/*pathology
Animals ; Ataxia Telangiectasia Mutated Proteins/antagonists & inhibitors ; Ataxia Telangiectasia Mutated Proteins/deficiency ; Ataxia Telangiectasia Mutated Proteins/metabolism ; Cell Line ; Cell Transformation, Neoplastic/pathology ; Chromatin/genetics ; Clustered Regularly Interspaced Short Palindromic Repeats ; Female ; Fibroblasts/pathology ; Gene Knockout Techniques ; Gene Targeting/methods ; Genes, p53 ; Humans ; Mammary Neoplasms, Animal/genetics ; Mammary Neoplasms, Animal/pathology ; Mice ; Mice, Nude ; Neoplasm Proteins/antagonists & inhibitors ; Neoplasm Proteins/deficiency ; Neoplasm Proteins/genetics ; Neoplasm Proteins/metabolism ; RNA, Messenger/metabolism ; Transcriptional Activation ; Transcriptome/physiology ; Tripartite Motif-Containing Protein 28/genetics ; Tripartite Motif-Containing Protein 28/metabolism ; Tumor Stem Cell Assay/methods
Czasopismo naukowe
Tytuł :
STUB1 is targeted by the SUMO-interacting motif of EBNA1 to maintain Epstein-Barr Virus latency.
Autorzy :
Wang Y; MOE&NHC&CAMS Key Laboratory of Medical Molecular Virology, Department of Medical Microbiology and Parasitology, Biosafety Level 3 Laboratory, School of Basic Medical Science, Shanghai Medical College, Fudan University, Shanghai, P. R. China.
Du S; MOE&NHC&CAMS Key Laboratory of Medical Molecular Virology, Department of Medical Microbiology and Parasitology, Biosafety Level 3 Laboratory, School of Basic Medical Science, Shanghai Medical College, Fudan University, Shanghai, P. R. China.
Zhu C; MOE&NHC&CAMS Key Laboratory of Medical Molecular Virology, Department of Medical Microbiology and Parasitology, Biosafety Level 3 Laboratory, School of Basic Medical Science, Shanghai Medical College, Fudan University, Shanghai, P. R. China.
Wang C; MOE&NHC&CAMS Key Laboratory of Medical Molecular Virology, Department of Medical Microbiology and Parasitology, Biosafety Level 3 Laboratory, School of Basic Medical Science, Shanghai Medical College, Fudan University, Shanghai, P. R. China.
Yu N; MOE&NHC&CAMS Key Laboratory of Medical Molecular Virology, Department of Medical Microbiology and Parasitology, Biosafety Level 3 Laboratory, School of Basic Medical Science, Shanghai Medical College, Fudan University, Shanghai, P. R. China.
Lin Z; MOE&NHC&CAMS Key Laboratory of Medical Molecular Virology, Department of Medical Microbiology and Parasitology, Biosafety Level 3 Laboratory, School of Basic Medical Science, Shanghai Medical College, Fudan University, Shanghai, P. R. China.
Gan J; MOE&NHC&CAMS Key Laboratory of Medical Molecular Virology, Department of Medical Microbiology and Parasitology, Biosafety Level 3 Laboratory, School of Basic Medical Science, Shanghai Medical College, Fudan University, Shanghai, P. R. China.; ShengYushou Center of Cell Biology and Immunology, School of Life Science and Biotechnology, Shanghai Jiao Tong University, Shanghai, P. R. China.
Guo Y; Department of Gynecology, Key laboratory of AIDS immunology of Ministry of Health, First Affiliated Hospital of China Medical University, Shengyang, P. R. China.
Huang X; Technical Center For Animal, Plant and Food Inspection and Quarantine of Shanghai Customs, Shanghai, P. R. China.
He Y; Technical Center For Animal, Plant and Food Inspection and Quarantine of Shanghai Customs, Shanghai, P. R. China.
Robertson E; Department of Otorhinolaryngology-Head and Neck surgery, Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
Qu D; MOE&NHC&CAMS Key Laboratory of Medical Molecular Virology, Department of Medical Microbiology and Parasitology, Biosafety Level 3 Laboratory, School of Basic Medical Science, Shanghai Medical College, Fudan University, Shanghai, P. R. China.
Wei F; ShengYushou Center of Cell Biology and Immunology, School of Life Science and Biotechnology, Shanghai Jiao Tong University, Shanghai, P. R. China.
Cai Q; MOE&NHC&CAMS Key Laboratory of Medical Molecular Virology, Department of Medical Microbiology and Parasitology, Biosafety Level 3 Laboratory, School of Basic Medical Science, Shanghai Medical College, Fudan University, Shanghai, P. R. China.; Expert Workstation, Baoji Central Hospital, Baoji, P. R. China.
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Źródło :
PLoS pathogens [PLoS Pathog] 2020 Mar 16; Vol. 16 (3), pp. e1008447. Date of Electronic Publication: 2020 Mar 16 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Epstein-Barr Virus Nuclear Antigens/*metabolism
Herpesvirus 4, Human/*physiology
Small Ubiquitin-Related Modifier Proteins/*metabolism
Ubiquitin-Protein Ligases/*metabolism
Virus Latency/*physiology
Amino Acid Motifs ; Cell Line ; Epstein-Barr Virus Nuclear Antigens/genetics ; Humans ; Small Ubiquitin-Related Modifier Proteins/genetics ; Tripartite Motif-Containing Protein 28/genetics ; Tripartite Motif-Containing Protein 28/metabolism ; Ubiquitin-Protein Ligases/genetics ; Ubiquitin-Specific Peptidase 7/genetics ; Ubiquitin-Specific Peptidase 7/metabolism
Czasopismo naukowe
Tytuł :
TRIM28 promotes HIV-1 latency by SUMOylating CDK9 and inhibiting P-TEFb.
Autorzy :
Ma X; Institute of Human Virology, Sun Yat-sen University, Guangzhou, China.; Key Laboratory of Tropical Disease Control of Ministry of Education, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
Yang T; Institute of Human Virology, Sun Yat-sen University, Guangzhou, China.; Key Laboratory of Tropical Disease Control of Ministry of Education, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
Luo Y; Institute of Human Virology, Sun Yat-sen University, Guangzhou, China.; Key Laboratory of Tropical Disease Control of Ministry of Education, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
Wu L; Institute of Human Virology, Sun Yat-sen University, Guangzhou, China.; Key Laboratory of Tropical Disease Control of Ministry of Education, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
Jiang Y; Institute of Human Virology, Sun Yat-sen University, Guangzhou, China.; Key Laboratory of Tropical Disease Control of Ministry of Education, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
Song Z; Institute of Human Virology, Sun Yat-sen University, Guangzhou, China.; Key Laboratory of Tropical Disease Control of Ministry of Education, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
Pan T; Institute of Human Virology, Sun Yat-sen University, Guangzhou, China.; Key Laboratory of Tropical Disease Control of Ministry of Education, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
Liu B; Institute of Human Virology, Sun Yat-sen University, Guangzhou, China.; Key Laboratory of Tropical Disease Control of Ministry of Education, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
Liu G; College of Basic Medical Sciences, Shenyang Medical College, Shenyang, China.
Liu J; Institute of Human Virology, Sun Yat-sen University, Guangzhou, China.; Key Laboratory of Tropical Disease Control of Ministry of Education, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
Yu F; Key Laboratory of Tropical Disease Control of Ministry of Education, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
He Z; Key Laboratory of Tropical Disease Control of Ministry of Education, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
Zhang W; Key Laboratory of Tropical Disease Control of Ministry of Education, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
Yang J; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, China.
Liang L; Key Laboratory of Tropical Disease Control of Ministry of Education, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
Guan Y; Core Laboratory Platform for Medical Science, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
Zhang X; Key Laboratory of Tropical Disease Control of Ministry of Education, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
Li L; Department of Infectious Diseases, Guangzhou Eighth People's Hospital, Guangzhou, China.
Cai W; Department of Infectious Diseases, Guangzhou Eighth People's Hospital, Guangzhou, China.
Tang X; Department of Infectious Diseases, Guangzhou Eighth People's Hospital, Guangzhou, China.
Gao S; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, China.
Deng K; Key Laboratory of Tropical Disease Control of Ministry of Education, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
Zhang H; Key Laboratory of Tropical Disease Control of Ministry of Education, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
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Źródło :
ELife [Elife] 2019 Jan 17; Vol. 8. Date of Electronic Publication: 2019 Jan 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cyclin-Dependent Kinase 9/*genetics
HIV Infections/*genetics
HIV-1/*genetics
Positive Transcriptional Elongation Factor B/*genetics
Tripartite Motif-Containing Protein 28/*genetics
Virus Latency/*genetics
Cell Line, Tumor ; Cyclin-Dependent Kinase 9/metabolism ; Gene Expression Regulation, Viral ; HEK293 Cells ; HIV Infections/metabolism ; HIV Infections/virology ; HIV-1/physiology ; HeLa Cells ; Host-Pathogen Interactions/genetics ; Humans ; Positive Transcriptional Elongation Factor B/metabolism ; RNA Interference ; Sumoylation ; Tripartite Motif-Containing Protein 28/metabolism ; Virus Replication/genetics
Czasopismo naukowe
Tytuł :
TRIM28 down-regulation on methylation imprints in bovine preimplantation embryos.
Autorzy :
Ma X; 1College of Animal Science and Technology,Jilin Agricultural University,Changchun,Jilin,China.
Zhang S; 2State & Local Joint Engineering Laboratory for Animal Models of Human Diseases,Academy of Translational Medicine,First Hospital,Jilin University,Changchun,Jilin,China.
Zhang M; 1College of Animal Science and Technology,Jilin Agricultural University,Changchun,Jilin,China.
Zhu Y; 1College of Animal Science and Technology,Jilin Agricultural University,Changchun,Jilin,China.
Ma P; 1College of Animal Science and Technology,Jilin Agricultural University,Changchun,Jilin,China.
Yang S; 1College of Animal Science and Technology,Jilin Agricultural University,Changchun,Jilin,China.
Su L; 1College of Animal Science and Technology,Jilin Agricultural University,Changchun,Jilin,China.
Li Z; 2State & Local Joint Engineering Laboratory for Animal Models of Human Diseases,Academy of Translational Medicine,First Hospital,Jilin University,Changchun,Jilin,China.
Lv W; 1College of Animal Science and Technology,Jilin Agricultural University,Changchun,Jilin,China.
Luan W; 1College of Animal Science and Technology,Jilin Agricultural University,Changchun,Jilin,China.
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Źródło :
Zygote (Cambridge, England) [Zygote] 2018 Dec; Vol. 26 (6), pp. 449-456. Date of Electronic Publication: 2019 Jan 23.
Typ publikacji :
Journal Article
MeSH Terms :
Blastocyst/*metabolism
Oocytes/*physiology
Tripartite Motif-Containing Protein 28/*metabolism
Animals ; Cattle ; Down-Regulation ; Female ; Fertilization in Vitro ; Gene Expression Regulation, Developmental ; Gene Knockdown Techniques ; In Vitro Oocyte Maturation Techniques ; Lysine/metabolism ; Male ; Methylation ; Nuclear Transfer Techniques ; RNA, Small Interfering ; Tripartite Motif-Containing Protein 28/genetics
Czasopismo naukowe
Tytuł :
Endogenous Retrovirus Activation as a Key Mechanism of Anti-Tumor Immune Response in Radiotherapy.
Autorzy :
Lee AK; Department of Pharmacology and Cancer Biology, Duke University Graduate School, Durham, North Carolina.
Pan D; Department of Dermatology.
Bao X; Department of Dermatology.
Hu M; Department of Dermatology.
Li F; Department of Dermatology.
Li CY; Department of Pharmacology and Cancer Biology, Duke University Graduate School, Durham, North Carolina.; Department of Dermatology.; Department of Duke Cancer Institute, Duke University School of Medicine, Durham, North Carolina.
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Źródło :
Radiation research [Radiat Res] 2020 Apr; Vol. 193 (4), pp. 305-317. Date of Electronic Publication: 2020 Feb 19.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
DNA Breaks, Double-Stranded/*radiation effects
Immunity, Innate/*immunology
Neoplasms/*immunology
Neoplasms/*radiotherapy
A549 Cells ; Adaptor Proteins, Signal Transducing/genetics ; Animals ; Endogenous Retroviruses/genetics ; Endogenous Retroviruses/radiation effects ; Gene Expression Regulation, Neoplastic/radiation effects ; Gene Knockout Techniques ; Humans ; Immunity, Innate/radiation effects ; Immunotherapy/methods ; Interferon-Induced Helicase, IFIH1/genetics ; Mice ; Neoplasms/genetics ; Neoplasms/pathology ; Protein-Serine-Threonine Kinases/genetics ; Signal Transduction/radiation effects ; Tripartite Motif-Containing Protein 28/genetics ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
Expression of TRIM28 correlates with proliferation and Bortezomib-induced apoptosis in B-cell non-Hodgkin lymphoma.
Autorzy :
Zhang PP; a Department of Immunity, Medical College , Nantong University , Nantong , P. R. China.
Ding DZ; b Department of Orthopaedics , Affiliated Hospital of Nantong University , Nantong , Jiangsu , P. R. China.
Shi B; c Department of Oncology , The Second People's Hospital of Nantong , Nantong , P. R. China.
Zhang SQ; d Department of Clinical Laboratory , The Second People's Hospital of Nantong , Nantong , P. R. China.
Gu LL; d Department of Clinical Laboratory , The Second People's Hospital of Nantong , Nantong , P. R. China.
Wang YC; e Department of Pathogenic Biology, Medical College , Nantong University , Nantong , P. R. China.
Cheng C; a Department of Immunity, Medical College , Nantong University , Nantong , P. R. China.
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Źródło :
Leukemia & lymphoma [Leuk Lymphoma] 2018 Nov; Vol. 59 (11), pp. 2639-2649. Date of Electronic Publication: 2018 Mar 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Apoptosis/*drug effects
Bortezomib/*pharmacology
Cell Proliferation/*drug effects
Lymphoma, B-Cell/*metabolism
Tripartite Motif-Containing Protein 28/*biosynthesis
Antineoplastic Agents/pharmacology ; Cell Line, Tumor ; Female ; Humans ; Immunohistochemistry ; Kaplan-Meier Estimate ; Lymphoma, B-Cell/pathology ; Male ; Middle Aged ; RNA Interference ; Tripartite Motif-Containing Protein 28/genetics
Czasopismo naukowe
Tytuł :
Post-transcriptional regulation of cancer/testis antigen MAGEC2 expression by TRIM28 in tumor cells.
Autorzy :
Song X; Department of Immunology, School of Basic Medical Sciences, Key Laboratory of Medical Immunology of Ministry of Health, Peking University, Beijing, 100191, China.
Guo C; Department of Immunology, School of Basic Medical Sciences, Key Laboratory of Medical Immunology of Ministry of Health, Peking University, Beijing, 100191, China.
Zheng Y; Department of Immunology, School of Basic Medical Sciences, Key Laboratory of Medical Immunology of Ministry of Health, Peking University, Beijing, 100191, China.
Wang Y; Department of Immunology, School of Basic Medical Sciences, Key Laboratory of Medical Immunology of Ministry of Health, Peking University, Beijing, 100191, China.
Jin Z; Department of Hepatobiliary Surgery, Peking University People's Hospital, Beijing, 100044, China. .
Yin Y; Department of Immunology, School of Basic Medical Sciences, Key Laboratory of Medical Immunology of Ministry of Health, Peking University, Beijing, 100191, China. .
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Źródło :
BMC cancer [BMC Cancer] 2018 Oct 11; Vol. 18 (1), pp. 971. Date of Electronic Publication: 2018 Oct 11.
Typ publikacji :
Journal Article
MeSH Terms :
Antigens, Neoplasm/*metabolism
Neoplasm Proteins/*metabolism
Neoplasms/*metabolism
Tripartite Motif-Containing Protein 28/*metabolism
A549 Cells ; Antigens, Neoplasm/genetics ; Carcinoma, Hepatocellular/genetics ; Carcinoma, Hepatocellular/metabolism ; Cell Line, Tumor ; Gene Expression Regulation, Neoplastic ; Gene Knockdown Techniques ; Humans ; Liver Neoplasms/genetics ; Liver Neoplasms/metabolism ; Melanoma/genetics ; Melanoma/metabolism ; Neoplasm Proteins/genetics ; Neoplasms/genetics ; Protein Binding ; Tripartite Motif-Containing Protein 28/genetics
Czasopismo naukowe

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