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Wyszukujesz frazę ""Triple Negative Breast Neoplasms"" wg kryterium: Temat


Tytuł :
Neoadjuvant paclitaxel/olaparib in comparison to paclitaxel/carboplatinum in patients with HER2-negative breast cancer and homologous recombination deficiency (GeparOLA study).
Autorzy :
Fasching PA; Department of Gynecology and Obstetrics, University Hospital Erlangen, Comprehensive Cancer Center Erlangen-Nuremberg, National Center for Tumor Diseases, Erlangen, Germany.
Link T; Klinik und Poliklinik für Frauenheilkunde und Geburtshilfe, Universitätsklinikum Carl Gustav Carus Dresden, Germany.
Hauke J; Center for Familial Breast and Ovarian Cancer, University of Cologne, Cologne, Germany.
Seither F; German Breast Group, Neu-Isenburg, Germany.
Jackisch C; Sana Klinikum Offenbach, Offenbach, Germany.
Klare P; MediOnko-Institut GbR Berlin, Berlin, Germany.
Schmatloch S; Elisabeth Krankenhaus Kassel, Kassel, Germany.
Hanusch C; Rotkreuzklinikum Munich, Munich, Germany.
Huober J; University Hospital Ulm, Ulm, Germany.
Stefek A; Johanniter-Krankenhaus Genthin-Stendal, Stendal, Germany.
Seiler S; German Breast Group, Neu-Isenburg, Germany.
Schmitt WD; Institute of Pathology, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Uleer C; Gemeinschaftspraxis Hildesheim, Hildesheim, Germany.
Doering G; Hämato-Onkologie im Medicum Bremen, Bremen, Germany.
Rhiem K; Center for Familial Breast and Ovarian Cancer, University of Cologne, Cologne, Germany.
Schneeweiss A; National Center for Tumor Diseases (NCT), Heidelberg University Hospital and German Cancer Research Center (DKFZ), Heidelberg, Germany.
Engels K; Center for Pathology, Cytology and Molecular Pathology Neuss, Neuss, Germany.
Denkert C; Institute of Pathology, Philipps-Universität Marburg und University Hospital Marburg (UKGM), Marburg, Germany.
Schmutzler RK; Center for Familial Breast and Ovarian Cancer, University of Cologne, Cologne, Germany.
Hahnen E; Center for Familial Breast and Ovarian Cancer, University of Cologne, Cologne, Germany.
Untch M; Helios-Klinikum Berlin-Buch, Berlin, Germany.
Burchardi N; German Breast Group, Neu-Isenburg, Germany.
Blohmer JU; Brustzentrum Charité-Universitätsmedizin Berlin, Berlin, Germany.
Loibl S; German Breast Group, Neu-Isenburg, Germany. Electronic address: .
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Corporate Authors :
German Breast Group and Arbeitsgemeinschaft Gynäkologische Onkologie Breast
Źródło :
Annals of oncology : official journal of the European Society for Medical Oncology [Ann Oncol] 2021 Jan; Vol. 32 (1), pp. 49-57. Date of Electronic Publication: 2020 Oct 21.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Breast Neoplasms*/drug therapy
Breast Neoplasms*/genetics
Triple Negative Breast Neoplasms*/drug therapy
Triple Negative Breast Neoplasms*/genetics
Adult ; Aged ; Antineoplastic Combined Chemotherapy Protocols/adverse effects ; Cyclophosphamide/adverse effects ; Homologous Recombination ; Humans ; Middle Aged ; Neoadjuvant Therapy ; Paclitaxel/adverse effects ; Phthalazines ; Piperazines ; Receptor, ErbB-2/genetics ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Assessment of structural chromosomal instability phenotypes as biomarkers of carboplatin response in triple negative breast cancer: the TNT trial.
Autorzy :
Sipos O; Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK.
Tovey H; Clinical Trials and Statistics Unit, The Institute of Cancer Research, London, UK.
Quist J; Breast Cancer Now Unit, King's College London Faculty of Life Sciences and Medicine, London, UK; School of Cancer and Pharmaceutical Sciences, King's College London Faculty of Life Sciences and Medicine, London, UK.
Haider S; Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK.
Nowinski S; School of Cancer and Pharmaceutical Sciences, King's College London Faculty of Life Sciences and Medicine, London, UK.
Gazinska P; Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK.
Kernaghan S; Clinical Trials and Statistics Unit, The Institute of Cancer Research, London, UK.
Toms C; Clinical Trials and Statistics Unit, The Institute of Cancer Research, London, UK.
Maguire S; Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, UK.
Orr N; Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, UK.
Linn SC; Division of Molecular Pathology, Netherlands Cancer Institute, Amsterdam, Netherlands.
Owen J; King's Health Partners Cancer Biobank, London, UK.
Gillett C; King's Health Partners Cancer Biobank, London, UK.
Pinder SE; School of Cancer and Pharmaceutical Sciences, King's College London Faculty of Life Sciences and Medicine, London, UK.
Bliss JM; Clinical Trials and Statistics Unit, The Institute of Cancer Research, London, UK.
Tutt A; Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK; Breast Cancer Now Unit, King's College London Faculty of Life Sciences and Medicine, London, UK; School of Cancer and Pharmaceutical Sciences, King's College London Faculty of Life Sciences and Medicine, London, UK.
Cheang MCU; Clinical Trials and Statistics Unit, The Institute of Cancer Research, London, UK.
Grigoriadis A; Breast Cancer Now Unit, King's College London Faculty of Life Sciences and Medicine, London, UK; School of Cancer and Pharmaceutical Sciences, King's College London Faculty of Life Sciences and Medicine, London, UK. Electronic address: .
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Źródło :
Annals of oncology : official journal of the European Society for Medical Oncology [Ann Oncol] 2021 Jan; Vol. 32 (1), pp. 58-65. Date of Electronic Publication: 2020 Oct 21.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Trinitrotoluene*
Triple Negative Breast Neoplasms*/drug therapy
Triple Negative Breast Neoplasms*/genetics
Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Biomarkers ; Carboplatin/therapeutic use ; Chromosomal Instability/genetics ; Humans ; Phenotype
Czasopismo naukowe
Tytuł :
Predictive value of tumor-infiltrating lymphocytes for response to neoadjuvant chemotherapy and breast cancer prognosis.
Autorzy :
Li X; West China School of Medicine, West China Hospital, Sichuan University, Chengdu, China.
Tan Q; Department of Breast Surgery, West China Hospital, Sichuan University, Chengdu, China.
Li H; Department of Breast Surgery, West China Hospital, Sichuan University, Chengdu, China.
Yang X; Department of Breast Surgery, West China Hospital, Sichuan University, Chengdu, China.
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Źródło :
Journal of surgical oncology [J Surg Oncol] 2021 Jan; Vol. 123 (1), pp. 89-95. Date of Electronic Publication: 2020 Oct 12.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Combined Chemotherapy Protocols/*therapeutic use
Lymph Nodes/*immunology
Lymphocytes, Tumor-Infiltrating/*immunology
Neoadjuvant Therapy/*mortality
Neoplasm Recurrence, Local/*immunology
Neoplasm, Residual/*immunology
Triple Negative Breast Neoplasms/*immunology
Adult ; Female ; Follow-Up Studies ; Humans ; Lymph Nodes/drug effects ; Lymph Nodes/pathology ; Lymphocytes, Tumor-Infiltrating/drug effects ; Lymphocytes, Tumor-Infiltrating/pathology ; Middle Aged ; Neoplasm Recurrence, Local/drug therapy ; Neoplasm Recurrence, Local/pathology ; Neoplasm, Residual/drug therapy ; Neoplasm, Residual/pathology ; Prognosis ; Retrospective Studies ; Survival Rate ; Triple Negative Breast Neoplasms/drug therapy ; Triple Negative Breast Neoplasms/pathology
Czasopismo naukowe
Tytuł :
Treatment Patterns and Clinical Outcomes of Adenoid Cystic Breast Carcinoma: A Single-Institution Experience.
Autorzy :
Goldbach MM; 14640 Department of Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Hoffman DI; 14640 Department of Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Burkbauer L; 14640 Department of Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Nayak A; Department of Pathology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Tchou J; 14640 Department of Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Rena Rowan Breast Center, Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
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Źródło :
The American surgeon [Am Surg] 2020 Dec; Vol. 86 (12), pp. 1684-1690. Date of Electronic Publication: 2020 Aug 26.
Typ publikacji :
Journal Article
MeSH Terms :
Carcinoma, Adenoid Cystic/*surgery
Triple Negative Breast Neoplasms/*surgery
Carcinoma, Adenoid Cystic/diagnostic imaging ; Carcinoma, Adenoid Cystic/pathology ; Chemotherapy, Adjuvant ; Female ; Humans ; Middle Aged ; Neoplasm Recurrence, Local ; Radiotherapy, Adjuvant ; Retrospective Studies ; Triple Negative Breast Neoplasms/diagnostic imaging ; Triple Negative Breast Neoplasms/pathology
Czasopismo naukowe
Tytuł :
Aldehyde Dehydrogenase 1-related Genes in Triple-negative Breast Cancer Investigated Using Network Analysis.
Autorzy :
Yamada A; Department of Gastroenterological Surgery, Yokohama City University Graduate School of Medicine, Kanagawa, Japan; .
Suzuki C; Department of Gastroenterological Surgery, Yokohama City University Graduate School of Medicine, Kanagawa, Japan.
Shima H; Department of Gastroenterological Surgery, Yokohama City University Graduate School of Medicine, Kanagawa, Japan.
Kida K; Department of Breast and Thyroid Surgery, Yokohama City University Medical Center, Kanagawa, Japan.
Adachi S; Department of Breast and Thyroid Surgery, Yokohama City University Medical Center, Kanagawa, Japan.
Yamamoto S; Department of Breast and Thyroid Surgery, Yokohama City University Medical Center, Kanagawa, Japan.
Narui K; Department of Breast and Thyroid Surgery, Yokohama City University Medical Center, Kanagawa, Japan.
Tanabe M; Department of Pathology, Yokohama City University Medical Center, Kanagawa, Japan.
Shimizu D; Department of Breast Surgery, Yokohama City Minato Red Cross Hospital, Kanagawa, Japan.
Taniguchi R; KM data Inc., Tokyo, Japan.
Oshi M; Department of Gastroenterological Surgery, Yokohama City University Graduate School of Medicine, Kanagawa, Japan.; Division of Breast Surgery, Department of Surgical Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, NY, U.S.A.
Takabe K; Department of Gastroenterological Surgery, Yokohama City University Graduate School of Medicine, Kanagawa, Japan.; Division of Breast Surgery, Department of Surgical Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, NY, U.S.A.; Department of Breast Disease, Tokyo Medical University Hospital, Tokyo, Japan.
Miyagi Y; Molecular Pathology and Genetics Division, Kanagawa Cancer Center Research Institute, Kanagawa, Japan.
Ichikawa Y; Department of Oncology, Yokohama City University, Kanagawa, Japan.
Ishikawa T; Department of Breast Disease, Tokyo Medical University Hospital, Tokyo, Japan.
Endo I; Department of Gastroenterological Surgery, Yokohama City University Graduate School of Medicine, Kanagawa, Japan.
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Źródło :
Anticancer research [Anticancer Res] 2020 Dec; Vol. 40 (12), pp. 6733-6742.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Regulatory Networks*
Genes, Neoplasm*
Aldehyde Dehydrogenase/*metabolism
Triple Negative Breast Neoplasms/*enzymology
Triple Negative Breast Neoplasms/*genetics
Cohort Studies ; Down-Regulation/genetics ; Female ; Gene Expression Regulation, Neoplastic ; Gene Ontology ; Humans ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Signal Transduction ; Triple Negative Breast Neoplasms/pathology ; Up-Regulation/genetics
Czasopismo naukowe
Tytuł :
Addition of chemotherapy to local therapy in women aged 70 years or older with triple-negative breast cancer: a propensity-matched analysis.
Autorzy :
Crozier JA; Division of Cancer Medicine, Baptist MD Anderson Cancer Center, Jacksonville, FL, USA.
Pezzi TA; Division of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Hodge C; Department of Surgery, Abington-Jefferson Health, Abington, PA, USA.
Janeva S; Department of Surgery, Sahlgrenska University Hospital, Gothenburg, Region Västra Götaland, Sweden.
Lesnikoski BA; Division of Surgery, Baptist MD Anderson Cancer Center, Jacksonville, FL, USA.
Samiian L; Division of Surgery, Baptist MD Anderson Cancer Center, Jacksonville, FL, USA.
Devereaux A; Division of Cancer Medicine, Baptist MD Anderson Cancer Center, Jacksonville, FL, USA.
Hammond W; Division of Cancer Medicine, Baptist MD Anderson Cancer Center, Jacksonville, FL, USA.
Audisio RA; Department of Surgery, Institute of Clinical Sciences, Sahlgrenska University Hospital, Gothenburg, Sweden.
Pezzi CM; Division of Surgery, Baptist MD Anderson Cancer Center, Jacksonville, FL, USA. Electronic address: .
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Źródło :
The Lancet. Oncology [Lancet Oncol] 2020 Dec; Vol. 21 (12), pp. 1611-1619.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents/*therapeutic use
Triple Negative Breast Neoplasms/*drug therapy
Aged ; Aged, 80 and over ; Antineoplastic Agents/adverse effects ; Chemotherapy, Adjuvant ; Clinical Decision-Making ; Databases, Factual ; Female ; Humans ; Neoplasm Staging ; Propensity Score ; Retrospective Studies ; Risk Assessment ; Risk Factors ; Time Factors ; Treatment Outcome ; Triple Negative Breast Neoplasms/mortality ; Triple Negative Breast Neoplasms/pathology ; United States
Czasopismo naukowe
Tytuł :
The Usefulness of Bayesian Network in Assessing the Risk of Triple-Negative Breast Cancer.
Autorzy :
Huang Y; Department of Medical Statistics and Epidemiology, School of Public Health, Sun Yat-Sen University, No. 74 Zhongshan II Road, Guangzhou 510080, China.
Zheng C; Department of Radiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, No. 107 Yanjiang Road West, Guangzhou 510120, China; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Medical Research Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, No. 107 Yanjiang Road West, Guangzhou 510120, China.
Zhang X; Department of Radiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, No. 107 Yanjiang Road West, Guangzhou 510120, China; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Medical Research Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, No. 107 Yanjiang Road West, Guangzhou 510120, China.
Cheng Z; Department of Radiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, No. 107 Yanjiang Road West, Guangzhou 510120, China; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Medical Research Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, No. 107 Yanjiang Road West, Guangzhou 510120, China.
Yang Z; Department of Radiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, No. 107 Yanjiang Road West, Guangzhou 510120, China; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Medical Research Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, No. 107 Yanjiang Road West, Guangzhou 510120, China.
Hao Y; Department of Medical Statistics and Epidemiology, School of Public Health, Sun Yat-Sen University, No. 74 Zhongshan II Road, Guangzhou 510080, China.
Shen J; Department of Radiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, No. 107 Yanjiang Road West, Guangzhou 510120, China; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Medical Research Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, No. 107 Yanjiang Road West, Guangzhou 510120, China. Electronic address: .
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Źródło :
Academic radiology [Acad Radiol] 2020 Dec; Vol. 27 (12), pp. e282-e291. Date of Electronic Publication: 2020 Feb 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Breast Neoplasms*
Triple Negative Breast Neoplasms*/diagnostic imaging
Triple Negative Breast Neoplasms*/epidemiology
Adult ; Bayes Theorem ; Contrast Media ; Female ; Humans ; Magnetic Resonance Imaging ; Middle Aged ; Retrospective Studies
Czasopismo naukowe
Tytuł :
CD68- and CD163-positive tumor-associated macrophages in triple negative cancer of the breast.
Autorzy :
Jamiyan T; Department of Diagnostic Pathology, Dokkyo Medical University, 880 Kitakobayashi, Mibu, Shimotsuga District, Tochigi, 321-0293, Japan.; Department of Pathology and Forensic medicine, Mongolian National University of Medical Sciences, Jamyan St 3, Ulaanbaatar, 14210, Mongolia.
Kuroda H; Department of Diagnostic Pathology, Dokkyo Medical University, 880 Kitakobayashi, Mibu, Shimotsuga District, Tochigi, 321-0293, Japan. .; Department of Diagnostic Pathology, Tokyo Women's Medical University, Medical Center East, 2-1-10 Nishiogu, Arakawa-ku, Tokyo 116-8567, Japan. .
Yamaguchi R; Department of Pathology and Laboratory Medicine, Kurume University Medical Center, 155-1 Kokubumachi, Kurume, Fukuoka, 839-0863, Japan.
Abe A; Breast center, Dokkyo Medical University, 880 Kitakobayashi, Mibu, Shimotsuga District, Tochigi 321-0293, Japan.; Department of Surgery II, Dokkyo Medical University, 880 Kitakobayashi, Mibu, Shimotsuga District, Tochigi, 321-0293, Japan.
Hayashi M; Breast center, Dokkyo Medical University, 880 Kitakobayashi, Mibu, Shimotsuga District, Tochigi 321-0293, Japan.
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Źródło :
Virchows Archiv : an international journal of pathology [Virchows Arch] 2020 Dec; Vol. 477 (6), pp. 767-775. Date of Electronic Publication: 2020 Jun 30.
Typ publikacji :
Journal Article
MeSH Terms :
Triple Negative Breast Neoplasms/*immunology
Tumor-Associated Macrophages/*immunology
Adult ; Aged ; Antigens, CD/immunology ; Antigens, Differentiation, Myelomonocytic/immunology ; Female ; Humans ; Middle Aged ; Prognosis ; Receptors, Cell Surface/immunology ; Triple Negative Breast Neoplasms/mortality ; Triple Negative Breast Neoplasms/pathology ; Tumor Microenvironment/immunology ; Tumor-Associated Macrophages/pathology
Czasopismo naukowe
Tytuł :
Construction of an immune-related genes nomogram for the preoperative prediction of axillary lymph node metastasis in triple-negative breast cancer.
Autorzy :
Tan W; Department of Breast Surgery, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China.
Xie X; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China.
Huang Z; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China.
Chen L; Department of Breast Surgery, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China.
Tang W; Department of Breast Surgery, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China.
Zhu R; East Hospital Affiliated to Tongji University, Shanghai, China.
Ye X; Department of Breast Surgery, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China.
Zhang X; Department of Breast Surgery, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China.
Pan L; Department of Breast Surgery, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China.
Gao J; Department of Breast Surgery, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China.
Tang H; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China.
Zheng W; Department of Breast Surgery, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China.
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Źródło :
Artificial cells, nanomedicine, and biotechnology [Artif Cells Nanomed Biotechnol] 2020 Dec; Vol. 48 (1), pp. 288-297.
Typ publikacji :
Clinical Trial; Journal Article; Validation Study; Video-Audio Media
MeSH Terms :
Genes, Neoplasm*
Nomograms*
Preoperative Care*
Triple Negative Breast Neoplasms*/genetics
Triple Negative Breast Neoplasms*/immunology
Triple Negative Breast Neoplasms*/pathology
Triple Negative Breast Neoplasms*/surgery
Gene Expression Regulation, Neoplastic/*immunology
Adult ; Female ; Humans ; Lymphatic Metastasis ; Middle Aged ; Risk Factors
Czasopismo naukowe
Tytuł :
Budlein A methylacrylate demonstrates potent activity against triple-negative breast cancer by targeting IκBα kinase and exportin-1.
Autorzy :
Wang XZ; College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, Jiangsu 210046, China. Electronic address: .
Feng Y; College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, Jiangsu 210046, China.
Han YF; College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, Jiangsu 210046, China.
Bian Y; College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, Jiangsu 210046, China.
Liang J; College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, Jiangsu 210046, China.
Wen HM; College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, Jiangsu 210046, China.
Wu H; College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, Jiangsu 210046, China.
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Źródło :
Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 2020 Dec 01; Vol. 408, pp. 115263. Date of Electronic Publication: 2020 Oct 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antineoplastic Agents/*therapeutic use
I-kappa B Kinase/*antagonists & inhibitors
Karyopherins/*antagonists & inhibitors
Lactones/*therapeutic use
Methacrylates/*therapeutic use
Sesquiterpenes/*therapeutic use
Triple Negative Breast Neoplasms/*drug therapy
Animals ; Antineoplastic Agents/pharmacology ; Apoptosis/drug effects ; Cell Line, Tumor ; Cell Survival/drug effects ; Female ; Humans ; I-kappa B Kinase/genetics ; Karyopherins/genetics ; Lactones/pharmacology ; Methacrylates/pharmacology ; Mice, Inbred BALB C ; Mice, Nude ; NF-kappa B/metabolism ; RNA, Small Interfering/genetics ; Sesquiterpenes/pharmacology ; Triple Negative Breast Neoplasms/genetics ; Triple Negative Breast Neoplasms/metabolism
Czasopismo naukowe
Tytuł :
Adipophilin expression is an independent marker for poor prognosis of patients with triple-negative breast cancer: An immunohistochemical study.
Autorzy :
Yoshikawa K; Department of Pathology and Clinical Laboratory, Kansai Medical University, Osaka, Japan.; Department of Surgery, Kansai Medical University, Osaka, Japan.
Ishida M; Department of Pathology and Clinical Laboratory, Kansai Medical University, Osaka, Japan.
Yanai H; Department of Surgery, Kansai Medical University, Osaka, Japan.
Tsuta K; Department of Pathology and Clinical Laboratory, Kansai Medical University, Osaka, Japan.
Sekimoto M; Department of Surgery, Kansai Medical University, Osaka, Japan.
Sugie T; Department of Surgery, Kansai Medical University, Osaka, Japan.
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Źródło :
PloS one [PLoS One] 2020 Nov 17; Vol. 15 (11), pp. e0242563. Date of Electronic Publication: 2020 Nov 17 (Print Publication: 2020).
Typ publikacji :
Journal Article
MeSH Terms :
Neoplasm Recurrence, Local/*genetics
Perilipin-2/*genetics
Triple Negative Breast Neoplasms/*genetics
Adult ; Aged ; Aged, 80 and over ; Biomarkers, Tumor/genetics ; Chemotherapy, Adjuvant ; Disease-Free Survival ; Female ; Gene Expression/genetics ; Gene Expression Regulation, Neoplastic/genetics ; Humans ; Middle Aged ; Perilipin-2/metabolism ; Prognosis ; Recurrence ; Triple Negative Breast Neoplasms/immunology ; Triple Negative Breast Neoplasms/metabolism
Czasopismo naukowe
Tytuł :
Zr-Labeled Multifunctional Liposomes Conjugate Chitosan for PET-Trackable Triple-Negative Breast Cancer Stem Cell Targeted Therapy.
Autorzy :
Yang R; Research Institute for Reproductive Health and Genetic Diseases, Affiliated Wuxi Maternity and Child Health Care Hospital of Nanjing Medical University, Wuxi 214002, People's Republic of China.
Lu M; Internal Medicine, Affiliated Wuxi Maternity and Child Health Care Hospital of Nanjing Medical University, Wuxi 214002, People's Republic of China.
Ming L; Research Institute for Reproductive Health and Genetic Diseases, Affiliated Wuxi Maternity and Child Health Care Hospital of Nanjing Medical University, Wuxi 214002, People's Republic of China.
Chen Y; Research Institute for Reproductive Health and Genetic Diseases, Affiliated Wuxi Maternity and Child Health Care Hospital of Nanjing Medical University, Wuxi 214002, People's Republic of China.
Cheng K; Research Institute for Reproductive Health and Genetic Diseases, Affiliated Wuxi Maternity and Child Health Care Hospital of Nanjing Medical University, Wuxi 214002, People's Republic of China.
Zhou J; Research Institute for Reproductive Health and Genetic Diseases, Affiliated Wuxi Maternity and Child Health Care Hospital of Nanjing Medical University, Wuxi 214002, People's Republic of China.
Jiang S; Research Institute for Reproductive Health and Genetic Diseases, Affiliated Wuxi Maternity and Child Health Care Hospital of Nanjing Medical University, Wuxi 214002, People's Republic of China.
Lin Z; Ministry of Education Key Laboratory for Analytical Science of Food Safety and Biology, Fujian Provincial Key Laboratory of Analysis and Detection for Food Safety, College of Chemistry, Fuzhou University, Fuzhou 350116, People's Republic of China.
Chen D; Research Institute for Reproductive Health and Genetic Diseases, Affiliated Wuxi Maternity and Child Health Care Hospital of Nanjing Medical University, Wuxi 214002, People's Republic of China.
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Źródło :
International journal of nanomedicine [Int J Nanomedicine] 2020 Nov 17; Vol. 15, pp. 9061-9074. Date of Electronic Publication: 2020 Nov 17 (Print Publication: 2020).
Typ publikacji :
Journal Article
MeSH Terms :
Liposomes/*chemistry
Neoplastic Stem Cells/*drug effects
Radioisotopes/*chemistry
Triple Negative Breast Neoplasms/*diagnostic imaging
Triple Negative Breast Neoplasms/*drug therapy
Zirconium/*chemistry
Adult ; Aged ; Animals ; Antineoplastic Agents/chemistry ; Antineoplastic Agents/pharmacokinetics ; Cell Line, Tumor ; Chitosan/chemistry ; Female ; Humans ; Hyaluronan Receptors/chemistry ; Hyaluronan Receptors/metabolism ; Liposomes/pharmacokinetics ; Mice, Nude ; Middle Aged ; Molecular Docking Simulation ; Molecular Targeted Therapy/methods ; Neoplastic Stem Cells/metabolism ; Neoplastic Stem Cells/pathology ; Positron-Emission Tomography/methods ; Tissue Distribution ; Triple Negative Breast Neoplasms/pathology ; Xanthones/pharmacokinetics ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
Prognostic role of microRNA 182 and microRNA 18a in locally advanced triple negative breast cancer.
Autorzy :
Bajaj R; Department of Medical Oncology, International Oncology Services, Fortis Hospital, UP, India.
Tripathi R; Department of Research, Rajiv Gandhi Cancer Institute & Research Centre, Delhi, India.
Sridhar TS; Department of Molecular Medicine, St John's Research Institute, Karnataka, India.
Korlimarla A; Department of Molecular Medicine, St John's Research Institute, Karnataka, India.
Choudhury KD; Department of Medical Oncology, International Oncology Services, Fortis Hospital, UP, India.
Suryavanshi M; Department of Molecular Diagnostics and Cell Biology, Rajiv Gandhi Cancer Institute and Research Centre, New Delhi, India.
Mehta A; Department of Pathology, Rajiv Gandhi Cancer Institute & Research Centre, Delhi, India.
Doval DC; Department of Medical Oncology, Rajiv Gandhi Cancer Institute & Research Centre, Delhi, India.
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Źródło :
PloS one [PLoS One] 2020 Nov 11; Vol. 15 (11), pp. e0242190. Date of Electronic Publication: 2020 Nov 11 (Print Publication: 2020).
Typ publikacji :
Journal Article
MeSH Terms :
Biomarkers, Tumor/*genetics
MicroRNAs/*genetics
Triple Negative Breast Neoplasms/*genetics
Adult ; Biomarkers, Tumor/metabolism ; Female ; Humans ; MicroRNAs/metabolism ; Middle Aged ; Triple Negative Breast Neoplasms/metabolism ; Triple Negative Breast Neoplasms/pathology ; Up-Regulation
Czasopismo naukowe
Tytuł :
A comprehensive overview of metaplastic breast cancer: clinical features and molecular aberrations.
Autorzy :
Reddy TP; Houston Methodist Research Institute, 6670 Bertner Ave, Houston, TX, 77030, USA.; Texas A&M Health Science Center College of Medicine, 8447 Riverside Pkwy, Bryan, TX, 77807, USA.
Rosato RR; Houston Methodist Research Institute, 6670 Bertner Ave, Houston, TX, 77030, USA.
Li X; Winship Cancer Institute, Emory University School of Medicine, 1365 Clifton Rd, Atlanta, GA, 30322, USA.
Moulder S; The University of Texas MD Anderson Cancer Center, 1400 Holcombe Boulevard, Houston, TX, 77030, USA.
Piwnica-Worms H; The University of Texas MD Anderson Cancer Center, 1400 Holcombe Boulevard, Houston, TX, 77030, USA.
Chang JC; Houston Methodist Research Institute, 6670 Bertner Ave, Houston, TX, 77030, USA. .; Houston Methodist Cancer Center/Weill Cornell Medicine, OPC 24, 6445 Main Street, Houston, TX, 77030, USA. .
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Źródło :
Breast cancer research : BCR [Breast Cancer Res] 2020 Nov 04; Vol. 22 (1), pp. 121. Date of Electronic Publication: 2020 Nov 04.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Epithelial-Mesenchymal Transition*
Wnt Signaling Pathway*
Breast Neoplasms/*pathology
Genes, Neoplasm/*genetics
Metaplasia/*pathology
Triple Negative Breast Neoplasms/*pathology
Breast Neoplasms/genetics ; Breast Neoplasms/metabolism ; Breast Neoplasms/therapy ; Cell Line, Tumor ; Female ; Humans ; Metaplasia/genetics ; Metaplasia/metabolism ; Metaplasia/therapy ; Molecular Targeted Therapy/methods ; Nitric Oxide Synthase/metabolism ; Phosphatidylinositol 3-Kinases/metabolism ; Triple Negative Breast Neoplasms/genetics ; Triple Negative Breast Neoplasms/metabolism ; Triple Negative Breast Neoplasms/therapy
Czasopismo naukowe
Tytuł :
Phase 2 study of buparlisib (BKM120), a pan-class I PI3K inhibitor, in patients with metastatic triple-negative breast cancer.
Autorzy :
Garrido-Castro AC; Department of Medical Oncology, Susan F. Smith Center for Women's Cancers, Dana-Farber Cancer Institute, Harvard Medical School, 450 Brookline Avenue, Boston, MA, 02215, USA.
Saura C; Department of Medical Oncology, Vall d'Hebron University Hospital, Universitat Autònoma de Barcelona, Barcelona, Spain.; Vall d'Hebron Institute of Oncology, VHIO, Barcelona, Spain.; SOLTI Breast Cancer Research Group, Barcelona, Spain.
Barroso-Sousa R; Department of Medical Oncology, Susan F. Smith Center for Women's Cancers, Dana-Farber Cancer Institute, Harvard Medical School, 450 Brookline Avenue, Boston, MA, 02215, USA.; Present Address: Hospital Sírio-Libanês, Brasilia, Brazil.
Guo H; Division of Biostatistics, Department of Data Sciences, Dana-Farber Cancer Institute, Boston, MA, USA.
Ciruelos E; Hospital 12 de Octubre, Madrid, Spain.
Bermejo B; Clinic University Hospital, INCLIVA Biomedical Research Institute, CIBERONC-ISCIII, Valencia, Spain.
Gavilá J; Fundación Instituto Valenciano De Oncología, Valencia, Spain.
Serra V; Experimental Therapeutics Group, Vall d'Hebron Institute of Oncology, Barcelona, Spain.
Prat A; Department of Medical Oncology, Translational Genomics and Targeted Therapeutics in Solid Tumors, IDIBAPS, Hospital Clínic of Barcelona, Barcelona, Spain.
Paré L; SOLTI Breast Cancer Research Group, Barcelona, Spain.
Céliz P; SOLTI Breast Cancer Research Group, Barcelona, Spain.
Villagrasa P; SOLTI Breast Cancer Research Group, Barcelona, Spain.
Li Y; Department of Biostatistics, Division of Basic Sciences, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Savoie J; Department of Medical Oncology, Susan F. Smith Center for Women's Cancers, Dana-Farber Cancer Institute, Harvard Medical School, 450 Brookline Avenue, Boston, MA, 02215, USA.
Xu Z; School of Communication, Northern Arizona University, Flagstaff, AZ, USA.
Arteaga CL; Harold C. Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, TX, USA.
Krop IE; Department of Medical Oncology, Susan F. Smith Center for Women's Cancers, Dana-Farber Cancer Institute, Harvard Medical School, 450 Brookline Avenue, Boston, MA, 02215, USA.
Solit DB; Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Mills GB; Knight Cancer Institute, Oregon Health & Science University, Portland, OR, USA.; Present Address: Division of Basic Science Research, Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Cantley LC; Sandra and Edward Meyer Cancer Center, Weill Cornell Medical College, New York, NY, USA.
Winer EP; Department of Medical Oncology, Susan F. Smith Center for Women's Cancers, Dana-Farber Cancer Institute, Harvard Medical School, 450 Brookline Avenue, Boston, MA, 02215, USA.
Lin NU; Department of Medical Oncology, Susan F. Smith Center for Women's Cancers, Dana-Farber Cancer Institute, Harvard Medical School, 450 Brookline Avenue, Boston, MA, 02215, USA. .
Rodon J; Department of Medical Oncology, Vall d'Hebron University Hospital, Universitat Autònoma de Barcelona, Barcelona, Spain.; SOLTI Breast Cancer Research Group, Barcelona, Spain.; Present Address: Department of Investigational Cancer Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
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Źródło :
Breast cancer research : BCR [Breast Cancer Res] 2020 Nov 02; Vol. 22 (1), pp. 120. Date of Electronic Publication: 2020 Nov 02.
Typ publikacji :
Clinical Trial, Phase II; Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Aminopyridines/*administration & dosage
Antineoplastic Combined Chemotherapy Protocols/*therapeutic use
Class I Phosphatidylinositol 3-Kinases/*antagonists & inhibitors
Morpholines/*administration & dosage
Triple Negative Breast Neoplasms/*drug therapy
Adult ; Aged ; Class I Phosphatidylinositol 3-Kinases/genetics ; Class I Phosphatidylinositol 3-Kinases/metabolism ; Disease Progression ; Female ; High-Throughput Nucleotide Sequencing ; Humans ; Middle Aged ; Neoplasm Metastasis ; Patient Safety ; Protein Kinase Inhibitors/administration & dosage ; Proteomics ; Response Evaluation Criteria in Solid Tumors ; Survival Rate ; Treatment Outcome ; Triple Negative Breast Neoplasms/enzymology ; Triple Negative Breast Neoplasms/genetics ; Triple Negative Breast Neoplasms/pathology
Czasopismo naukowe
Tytuł :
Clinicopathological factors associated with tumor-infiltrating lymphocyte reactivity in breast cancer.
Autorzy :
Lee H; Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Republic of Korea.
Kim YA; Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Republic of Korea.
Kim Y; Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Republic of Korea.
Park HS; Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Republic of Korea.
Seo JH; Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Republic of Korea.
Lee H; Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Republic of Korea.
Gong G; Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Republic of Korea. .
Lee HJ; Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Republic of Korea. .
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Źródło :
Cancer immunology, immunotherapy : CII [Cancer Immunol Immunother] 2020 Nov; Vol. 69 (11), pp. 2381-2391. Date of Electronic Publication: 2020 Jun 11.
Typ publikacji :
Journal Article
MeSH Terms :
Lymphocytes, Tumor-Infiltrating/*immunology
Triple Negative Breast Neoplasms/*immunology
Triple Negative Breast Neoplasms/*pathology
Adult ; Aged ; Aged, 80 and over ; Antineoplastic Agents/therapeutic use ; Chemotherapy, Adjuvant/methods ; Female ; Humans ; Middle Aged ; Neoadjuvant Therapy/methods ; Programmed Cell Death 1 Receptor/drug effects ; Programmed Cell Death 1 Receptor/metabolism ; Triple Negative Breast Neoplasms/drug therapy ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł :
Curcumin inhibits proteasome activity in triple-negative breast cancer cells through regulating p300/miR-142-3p/PSMB5 axis.
Autorzy :
Liu L; Department of Pathology & Pathophysiology, Wuhan University School of Basic Medical Sciences, Hubei Provincial Key Laboratory of Developmentally Originated Disease, Wuhan 430071, China.
Fu Y; Department of Pathology & Pathophysiology, Wuhan University School of Basic Medical Sciences, Hubei Provincial Key Laboratory of Developmentally Originated Disease, Wuhan 430071, China.
Zheng Y; Department of Pathology & Pathophysiology, Wuhan University School of Basic Medical Sciences, Hubei Provincial Key Laboratory of Developmentally Originated Disease, Wuhan 430071, China.
Ma M; Department of Pathology & Pathophysiology, Wuhan University School of Basic Medical Sciences, Hubei Provincial Key Laboratory of Developmentally Originated Disease, Wuhan 430071, China.
Wang C; Department of Pathology & Pathophysiology, Wuhan University School of Basic Medical Sciences, Hubei Provincial Key Laboratory of Developmentally Originated Disease, Wuhan 430071, China. Electronic address: .
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Źródło :
Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2020 Nov; Vol. 78, pp. 153312. Date of Electronic Publication: 2020 Aug 25.
Typ publikacji :
Journal Article
MeSH Terms :
Curcumin/*pharmacology
MicroRNAs/*genetics
Proteasome Endopeptidase Complex/*genetics
Proteasome Inhibitors/*pharmacology
Triple Negative Breast Neoplasms/*drug therapy
Animals ; Antineoplastic Agents, Phytogenic/pharmacology ; Cell Line, Tumor ; Cell Proliferation ; E1A-Associated p300 Protein/genetics ; E1A-Associated p300 Protein/metabolism ; Female ; Gene Expression Regulation, Neoplastic/drug effects ; Humans ; Mice, Inbred BALB C ; MicroRNAs/metabolism ; Proteasome Endopeptidase Complex/metabolism ; Triple Negative Breast Neoplasms/genetics ; Triple Negative Breast Neoplasms/metabolism ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
TBCRC 030: a phase II study of preoperative cisplatin versus paclitaxel in triple-negative breast cancer: evaluating the homologous recombination deficiency (HRD) biomarker.
Autorzy :
Mayer EL; Dana-Farber Cancer Institute, Boston, USA. Electronic address: .
Abramson V; Vanderbilt-Ingram Cancer Center, Vanderbilt University, Nashville, USA.
Jankowitz R; University of Pittsburgh Medical Center Hillman Cancer Center, Pittsburgh, USA.
Falkson C; University of Rochester Medical Center, Rochester, USA.
Marcom PK; Duke University Cancer Institute, Durham, USA.
Traina T; Memorial Sloan Kettering Cancer Center, New York, USA.
Carey L; University of North Carolina at Chapel Hill Lineberger Comprehensive Cancer Center, Chapel Hill, USA.
Rimawi M; Baylor College of Medicine, Houston, USA.
Specht J; Seattle Cancer Care Alliance, Seattle, USA.
Miller K; Indiana University Simon Cancer Center, Indianapolis, USA.
Stearns V; Johns Hopkins University Sidney Kimmel Cancer Center, Baltimore, USA.
Tung N; Beth Israel Deaconess Medical Center, Boston, USA.
Perou C; University of North Carolina at Chapel Hill Lineberger Comprehensive Cancer Center, Chapel Hill, USA.
Richardson AL; Johns Hopkins University Sidney Kimmel Cancer Center, Baltimore, USA.
Componeschi K; Dana-Farber Cancer Institute, Boston, USA.
Trippa L; Dana-Farber Cancer Institute, Boston, USA.
Tan-Wasielewski Z; Dana-Farber Cancer Institute, Boston, USA.
Timms K; Myriad Genetics Inc., Salt Lake City, USA.
Krop I; Dana-Farber Cancer Institute, Boston, USA.
Wolff AC; Johns Hopkins University Sidney Kimmel Cancer Center, Baltimore, USA.
Winer EP; Dana-Farber Cancer Institute, Boston, USA.
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Źródło :
Annals of oncology : official journal of the European Society for Medical Oncology [Ann Oncol] 2020 Nov; Vol. 31 (11), pp. 1518-1525. Date of Electronic Publication: 2020 Aug 13.
Typ publikacji :
Clinical Trial, Phase II; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Antineoplastic Combined Chemotherapy Protocols*/therapeutic use
Triple Negative Breast Neoplasms*/drug therapy
Triple Negative Breast Neoplasms*/genetics
Biomarkers ; Cisplatin/therapeutic use ; Homologous Recombination ; Humans ; Mutation ; Neoadjuvant Therapy ; Paclitaxel/therapeutic use ; Prospective Studies
Czasopismo naukowe
Tytuł :
Icariin-induced inhibition of SIRT6/NF-κB triggers redox mediated apoptosis and enhances anti-tumor immunity in triple-negative breast cancer.
Autorzy :
Song L; School of Medical and Life Sciences/Reproductive & Women-children Hospital, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Chen X; Department of Pathology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Mi L; School of Medical and Life Sciences/Reproductive & Women-children Hospital, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Liu C; School of Medical and Life Sciences/Reproductive & Women-children Hospital, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Zhu S; School of Medical and Life Sciences/Reproductive & Women-children Hospital, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Yang T; Department of Pathology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Luo X; School of Medical and Life Sciences/Reproductive & Women-children Hospital, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Zhang Q; School of Medical and Life Sciences/Reproductive & Women-children Hospital, Chengdu University of Traditional Chinese Medicine, Chengdu, China.; Department of Otolaryngology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Lu H; Innovative Institute of Liu-minru Female Science Inheritance, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Liang X; School of Medical and Life Sciences/Reproductive & Women-children Hospital, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
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Źródło :
Cancer science [Cancer Sci] 2020 Nov; Vol. 111 (11), pp. 4242-4256. Date of Electronic Publication: 2020 Oct 07.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis/*drug effects
Drugs, Chinese Herbal/*pharmacology
Flavonoids/*pharmacology
NF-kappa B/*metabolism
Oxidation-Reduction/*drug effects
Sirtuins/*metabolism
Triple Negative Breast Neoplasms/*metabolism
Animals ; Cell Line, Tumor ; Cell Movement/drug effects ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Disease Models, Animal ; Drugs, Chinese Herbal/chemistry ; Female ; Flavonoids/chemistry ; Gene Expression Profiling ; Humans ; Mice ; Mitochondria/drug effects ; Mitochondria/metabolism ; Models, Biological ; Neoplasm Metastasis ; Neoplasm Staging ; Reactive Oxygen Species/metabolism ; Transcription, Genetic ; Triple Negative Breast Neoplasms/drug therapy ; Triple Negative Breast Neoplasms/etiology ; Triple Negative Breast Neoplasms/pathology ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
MCU-dependent negative sorting of miR-4488 to extracellular vesicles enhances angiogenesis and promotes breast cancer metastatic colonization.
Autorzy :
Zheng X; Department of Occupational Health and Occupational Medicine, School of Public Health, Southern Medical University, 510515, Guangzhou, China.; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-Sen University Cancer Center, 510060, Guangzhou, China.
Lu S; Department of Occupational Health and Occupational Medicine, School of Public Health, Southern Medical University, 510515, Guangzhou, China.
He Z; Department of Occupational Health and Occupational Medicine, School of Public Health, Southern Medical University, 510515, Guangzhou, China.
Huang H; Department of Occupational Health and Occupational Medicine, School of Public Health, Southern Medical University, 510515, Guangzhou, China.
Yao Z; Department of Occupational Health and Occupational Medicine, School of Public Health, Southern Medical University, 510515, Guangzhou, China.
Miao Y; Department of Occupational Health and Occupational Medicine, School of Public Health, Southern Medical University, 510515, Guangzhou, China.
Cai C; Department of Occupational Health and Occupational Medicine, School of Public Health, Southern Medical University, 510515, Guangzhou, China. .
Zou F; Department of Occupational Health and Occupational Medicine, School of Public Health, Southern Medical University, 510515, Guangzhou, China. .
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Źródło :
Oncogene [Oncogene] 2020 Nov; Vol. 39 (46), pp. 6975-6989. Date of Electronic Publication: 2020 Oct 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Calcium Channels/*metabolism
Circulating MicroRNA/*metabolism
MicroRNAs/*metabolism
Neovascularization, Pathologic/*genetics
Triple Negative Breast Neoplasms/*pathology
Animals ; Cell Line, Tumor ; Cell Movement ; Chemokine CX3CL1/genetics ; Chemokine CX3CL1/metabolism ; Disease-Free Survival ; Extracellular Vesicles/metabolism ; Female ; Gene Expression Regulation, Neoplastic ; Human Umbilical Vein Endothelial Cells ; Humans ; Kaplan-Meier Estimate ; Mice ; Neoplasm Metastasis/genetics ; Neoplasm Metastasis/pathology ; Neovascularization, Pathologic/pathology ; Prognosis ; Triple Negative Breast Neoplasms/blood ; Triple Negative Breast Neoplasms/genetics ; Triple Negative Breast Neoplasms/mortality
Czasopismo naukowe

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