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Tytuł :
Simultaneous Quantification of Ursolic and Oleanolic Acids in Glechoma hederacea and Glechoma hirsuta by UPLC/MS/MS.
Autorzy :
Grabowska K; Jagiellonian University Medical College, Faculty of Pharmacy, Department of Pharmacognosy, Kraków, Poland.
Żmudzki P; Jagiellonian University Medical College, Faculty of Pharmacy, Department of Medicinal Chemistry, Kraków, Poland.
Wróbel-Biedrawa D; Jagiellonian University Medical College, Faculty of Pharmacy, Department of Pharmacognosy, Kraków, Poland.
Podolak I; Jagiellonian University Medical College, Faculty of Pharmacy, Department of Pharmacognosy, Kraków, Poland.
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Źródło :
Planta medica [Planta Med] 2021 Apr; Vol. 87 (4), pp. 305-313. Date of Electronic Publication: 2021 Jan 15.
Typ publikacji :
Journal Article
MeSH Terms :
Lamiaceae*
Oleanolic Acid*/analysis
Triterpenes*/analysis
Chromatography, High Pressure Liquid ; Chromatography, Liquid ; Pentacyclic Triterpenes ; Plant Extracts ; Tandem Mass Spectrometry
Czasopismo naukowe
Tytuł :
Pentacyclic Triterpenes from the resin of Liquidambar formosana have anti-angiogenic properties.
Autorzy :
Zhu Y; School of Pharmacy, Wenzhou Medical University, Wenzhou, 325035, People's Republic of China.
Guan YJ; School of Pharmacy, Wenzhou Medical University, Wenzhou, 325035, People's Republic of China.
Chen QZ; School of Pharmacy, Wenzhou Medical University, Wenzhou, 325035, People's Republic of China.
Yuan LH; School of Pharmacy, Wenzhou Medical University, Wenzhou, 325035, People's Republic of China.
Xu QQ; School of Pharmacy, Wenzhou Medical University, Wenzhou, 325035, People's Republic of China.
Zhou ML; School of Pharmacy, Wenzhou Medical University, Wenzhou, 325035, People's Republic of China.
Liu H; School of Pharmacy, Wenzhou Medical University, Wenzhou, 325035, People's Republic of China.
Lin W; School of Pharmacy, Wenzhou Medical University, Wenzhou, 325035, People's Republic of China.
Zhang ZD; School of Ophthalmology & Optometry, Wenzhou Medical University, Wenzhou, 325035, People's Republic of China.
Zhou ZL; School of Ophthalmology & Optometry, Wenzhou Medical University, Wenzhou, 325035, People's Republic of China.
Dong JY; School of Pharmacy, Wenzhou Medical University, Wenzhou, 325035, People's Republic of China. Electronic address: .
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Źródło :
Phytochemistry [Phytochemistry] 2021 Apr; Vol. 184, pp. 112676. Date of Electronic Publication: 2021 Feb 05.
Typ publikacji :
Journal Article
MeSH Terms :
Liquidambar*
Triterpenes*
Pentacyclic Triterpenes/pharmacology ; Phytochemicals ; Resins, Plant ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Chemical Strategies towards the Synthesis of Betulinic Acid and Its More Potent Antiprotozoal Analogues.
Autorzy :
Cunha AB; Instituto de Química, Universidade Federal da Bahia, Salvador 40170-280, BA, Brazil.
Batista R; Instituto de Química, Universidade Federal da Bahia, Salvador 40170-280, BA, Brazil.
Castro MÁ; Department of Pharmaceutical Sciences, Pharmaceutical Chemistry Section, CIETUS/IBSAL, Faculty of Pharmacy, University of Salamanca, 37007 Salamanca, Spain.
David JM; Instituto de Química, Universidade Federal da Bahia, Salvador 40170-280, BA, Brazil.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Feb 18; Vol. 26 (4). Date of Electronic Publication: 2021 Feb 18.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Antiprotozoal Agents/*chemical synthesis
Antiprotozoal Agents/*pharmacology
Pentacyclic Triterpenes/*chemical synthesis
Pentacyclic Triterpenes/*pharmacology
Antiprotozoal Agents/chemistry ; Models, Molecular ; Pentacyclic Triterpenes/chemistry ; Triterpenes/chemistry
Czasopismo naukowe
Tytuł :
A new pentacyclic triterpenoid from the leaves of Rhododendron dauricum L. with inhibition of NO production in LPS-induced RAW 264.7 cells.
Autorzy :
Wang J; Key Laboratory of Natural Resources of Changbai Mountain and Functional Molecules Ministry of Education, Yanbian University College of Pharmacy, Yanji, P. R. China.
Jin M; Department of Pharmacy, Yanbian University Hospital, Yanji, P. R. China.
Jin C; Key Laboratory of Natural Resources of Changbai Mountain and Functional Molecules Ministry of Education, Yanbian University College of Pharmacy, Yanji, P. R. China.
Ye C; Key Laboratory of Natural Resources of Changbai Mountain and Functional Molecules Ministry of Education, Yanbian University College of Pharmacy, Yanji, P. R. China.
Zhou Y; Key Laboratory of Natural Resources of Changbai Mountain and Functional Molecules Ministry of Education, Yanbian University College of Pharmacy, Yanji, P. R. China.
Wang R; Key Laboratory of Natural Resources of Changbai Mountain and Functional Molecules Ministry of Education, Yanbian University College of Pharmacy, Yanji, P. R. China.
Cui H; Key Laboratory of Natural Resources of Changbai Mountain and Functional Molecules Ministry of Education, Yanbian University College of Pharmacy, Yanji, P. R. China.
Zhou W; Key Laboratory of Natural Resources of Changbai Mountain and Functional Molecules Ministry of Education, Yanbian University College of Pharmacy, Yanji, P. R. China.
Li G; Key Laboratory of Natural Resources of Changbai Mountain and Functional Molecules Ministry of Education, Yanbian University College of Pharmacy, Yanji, P. R. China.
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Źródło :
Natural product research [Nat Prod Res] 2020 Dec; Vol. 34 (23), pp. 3313-3319. Date of Electronic Publication: 2019 Feb 27.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Inflammatory Agents, Non-Steroidal/*pharmacology
Nitric Oxide/*biosynthesis
Rhododendron/*chemistry
Triterpenes/*chemistry
Triterpenes/*pharmacology
Animals ; Anti-Inflammatory Agents, Non-Steroidal/chemistry ; Drug Evaluation, Preclinical ; Lipopolysaccharides/pharmacology ; Mice ; Molecular Structure ; Nitric Oxide/antagonists & inhibitors ; Oleanolic Acid/analysis ; Pentacyclic Triterpenes/analysis ; Plant Extracts/chemistry ; Plant Leaves/chemistry ; RAW 264.7 Cells ; Triterpenes/analysis
Czasopismo naukowe
Tytuł :
Bioactive triterpenoids from Sambucus javanica Blume.
Autorzy :
Chen F; Department of Traditional Medicine, Yunnan University of Chinese Medicine , Kunming , China.
Liu DL; Department of Traditional Medicine, Yunnan University of Chinese Medicine , Kunming , China.
Wang W; Department of Traditional Medicine, Yunnan University of Chinese Medicine , Kunming , China.
Lv XM; Department of Traditional Medicine, Yunnan University of Chinese Medicine , Kunming , China.
Li W; Department of Traditional Medicine, Yunnan University of Chinese Medicine , Kunming , China.
Shao LD; Department of Traditional Medicine, Yunnan University of Chinese Medicine , Kunming , China.
Wang WJ; Department of Traditional Medicine, Yunnan University of Chinese Medicine , Kunming , China.
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Źródło :
Natural product research [Nat Prod Res] 2020 Oct; Vol. 34 (19), pp. 2816-2821. Date of Electronic Publication: 2019 Apr 10.
Typ publikacji :
Journal Article
MeSH Terms :
Sambucus/*chemistry
Triterpenes/*chemistry
Triterpenes/*pharmacology
Animals ; Anti-Inflammatory Agents, Non-Steroidal/chemistry ; Anti-Inflammatory Agents, Non-Steroidal/pharmacology ; Lipopolysaccharides/pharmacology ; Mice ; Molecular Structure ; Nitric Oxide/metabolism ; Oleanolic Acid/analogs & derivatives ; Oleanolic Acid/isolation & purification ; Oleanolic Acid/pharmacology ; Pentacyclic Triterpenes/isolation & purification ; Pentacyclic Triterpenes/pharmacology ; Plant Components, Aerial/chemistry ; RAW 264.7 Cells ; Triterpenes/isolation & purification
Czasopismo naukowe
Tytuł :
Investigation of antiplasmodial efficacy of lupeol and ursolic acid isolated from Ficus benjamina leaves extract.
Autorzy :
Singh A; Department of Pharmaceutical Sciences, IKG Punjab Technical University, Kapurthala, India.; Department of Pharmacognosy, Khalsa College of Pharmacy, Amritsar, India.
Mukhtar HM; Department of Pharmacognosy and Phytochemistry, SBS College of Pharmacy, Tarn Taran, India.
Kaur H; PG Department of Chemistry, Khalsa College Amritsar, Punjab, India.
Kaur L; Department of Pharmacognosy, Khalsa College of Pharmacy, Amritsar, India.
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Źródło :
Natural product research [Nat Prod Res] 2020 Sep; Vol. 34 (17), pp. 2514-2517. Date of Electronic Publication: 2019 Jan 02.
Typ publikacji :
Journal Article
MeSH Terms :
Antimalarials/*isolation & purification
Antiprotozoal Agents/*isolation & purification
Ficus/*chemistry
Triterpenes/*isolation & purification
Antimalarials/pharmacology ; Antiprotozoal Agents/pharmacology ; Malaria/drug therapy ; Pentacyclic Triterpenes/isolation & purification ; Pentacyclic Triterpenes/pharmacology ; Plant Extracts/chemistry ; Plant Leaves/chemistry ; Plasmodium falciparum/drug effects ; Triterpenes/pharmacology
Czasopismo naukowe
Tytuł :
3-O-(E)-p-Coumaroyl betulinic acid possess anticancer activity and inhibit Notch signaling pathway in breast cancer cells and mammosphere.
Autorzy :
Kushwaha PP; Department of Biochemistry, Central University of Punjab, Bathinda, 151001, Punjab, India.
Singh AK; Department of Biochemistry, Central University of Punjab, Bathinda, 151001, Punjab, India.
Shuaib M; Department of Biochemistry, Central University of Punjab, Bathinda, 151001, Punjab, India.
Prajapati KS; Department of Biochemistry, Central University of Punjab, Bathinda, 151001, Punjab, India.
Vardhan PS; Department of Biochemistry, Central University of Punjab, Bathinda, 151001, Punjab, India.
Gupta S; Department of Urology, Case Western Reserve University, Cleveland, OH, 44106, USA.
Kumar S; Department of Biochemistry, Central University of Punjab, Bathinda, 151001, Punjab, India. Electronic address: .
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Źródło :
Chemico-biological interactions [Chem Biol Interact] 2020 Sep 01; Vol. 328, pp. 109200. Date of Electronic Publication: 2020 Jul 21.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents/*pharmacology
Breast Neoplasms/*drug therapy
Receptors, Notch/*antagonists & inhibitors
Receptors, Notch/*metabolism
Signal Transduction/*drug effects
Triterpenes/*pharmacology
Apoptosis/drug effects ; Breast Neoplasms/metabolism ; Cell Cycle Checkpoints/drug effects ; Cell Line ; Cell Line, Tumor ; Female ; HEK293 Cells ; Humans ; MCF-7 Cells ; Membrane Potential, Mitochondrial/drug effects ; Pentacyclic Triterpenes ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Tytuł :
Functional identification of BpMYB21 and BpMYB61 transcription factors responding to MeJA and SA in birch triterpenoid synthesis.
Autorzy :
Yin J; Key Laboratory of Saline-alkali Vegetation Ecology Restoration, Ministry of Education (Northeast Forestry University), Harbin, 150040, China.; College of Life Science, Northeast Forestry University, Harbin, 150040, China.; State Key Laboratory of Tree Genetics and Breeding, Northeast Forestry University, Harbin, 150040, China.
Sun L; Key Laboratory of Saline-alkali Vegetation Ecology Restoration, Ministry of Education (Northeast Forestry University), Harbin, 150040, China.
Li Y; Key Laboratory of Saline-alkali Vegetation Ecology Restoration, Ministry of Education (Northeast Forestry University), Harbin, 150040, China.
Xiao J; College of Life Science, Northeast Agricultere University, Harbin, 150010, China.
Wang S; Key Laboratory of Saline-alkali Vegetation Ecology Restoration, Ministry of Education (Northeast Forestry University), Harbin, 150040, China.
Yang J; Key Laboratory of Saline-alkali Vegetation Ecology Restoration, Ministry of Education (Northeast Forestry University), Harbin, 150040, China.
Qu Z; Key Laboratory of Saline-alkali Vegetation Ecology Restoration, Ministry of Education (Northeast Forestry University), Harbin, 150040, China.
Zhan Y; Key Laboratory of Saline-alkali Vegetation Ecology Restoration, Ministry of Education (Northeast Forestry University), Harbin, 150040, China. .; College of Life Science, Northeast Forestry University, Harbin, 150040, China. .; State Key Laboratory of Tree Genetics and Breeding, Northeast Forestry University, Harbin, 150040, China. .
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Źródło :
BMC plant biology [BMC Plant Biol] 2020 Aug 12; Vol. 20 (1), pp. 374. Date of Electronic Publication: 2020 Aug 12.
Typ publikacji :
Journal Article
MeSH Terms :
Acetates/*metabolism
Betula/*metabolism
Cyclopentanes/*metabolism
Oxylipins/*metabolism
Salicylates/*metabolism
Transcription Factors/*metabolism
Triterpenes/*metabolism
Betula/genetics ; Conserved Sequence ; Gene Expression Profiling ; Gene Expression Regulation, Plant ; Oleanolic Acid/metabolism ; Pentacyclic Triterpenes/metabolism ; Plants, Genetically Modified ; Promoter Regions, Genetic ; Protein Domains ; Squalene/metabolism ; Transcription Factors/genetics
Czasopismo naukowe
Tytuł :
Triple Negative Breast Cancer and Breast Epithelial Cells Differentially Reprogram Glucose and Lipid Metabolism upon Treatment with Triterpenic Acids.
Autorzy :
Guerra ÂR; Department of Chemistry, CICECO-Aveiro Institute of Materials, University of Aveiro, 3810-193 Aveiro, Portugal.; Centro de Biotecnologia Agrícola e Agro-Alimentar do Alentejo (CEBAL)/Instituto Politécnico de Beja (IPBeja), Apartado 6158, 7801-908 Beja, Portugal.
Paulino AF; Centro de Biotecnologia Agrícola e Agro-Alimentar do Alentejo (CEBAL)/Instituto Politécnico de Beja (IPBeja), Apartado 6158, 7801-908 Beja, Portugal.
Castro MM; Centro de Biotecnologia Agrícola e Agro-Alimentar do Alentejo (CEBAL)/Instituto Politécnico de Beja (IPBeja), Apartado 6158, 7801-908 Beja, Portugal.
Oliveira H; Department of Biology & CESAM, University of Aveiro, 3810-193 Aveiro, Portugal.
Duarte MF; Centro de Biotecnologia Agrícola e Agro-Alimentar do Alentejo (CEBAL)/Instituto Politécnico de Beja (IPBeja), Apartado 6158, 7801-908 Beja, Portugal.; MED-Mediterranean Institute for Agriculture, Environment and Development, CEBAL, 7801-908 Beja, Portugal.
Duarte IF; Department of Chemistry, CICECO-Aveiro Institute of Materials, University of Aveiro, 3810-193 Aveiro, Portugal.
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Źródło :
Biomolecules [Biomolecules] 2020 Aug 08; Vol. 10 (8). Date of Electronic Publication: 2020 Aug 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Breast/*drug effects
Epithelial Cells/*drug effects
Metabolome/*drug effects
Triple Negative Breast Neoplasms/*metabolism
Triterpenes/*pharmacology
Breast/metabolism ; Cell Cycle/drug effects ; Cell Line, Tumor ; Cell Survival/drug effects ; Citric Acid Cycle/drug effects ; Epithelial Cells/metabolism ; Female ; Glucose/metabolism ; Glycolysis/drug effects ; Hexosamines/metabolism ; Humans ; Lipid Metabolism/drug effects ; Magnetic Resonance Spectroscopy ; Metabolomics ; Pentacyclic Triterpenes
Czasopismo naukowe
Tytuł :
Discovery and structural optimization of 3-O-β-chacotriosyl oleanane-type triterpenoids as potent entry inhibitors of SARS-CoV-2 virus infections.
Autorzy :
Li H; Key Laboratory for Biobased Materials and Energy of Ministry of Education, College of Materials and Energy, South China Agricultural University, Guangzhou, 510642, China.
Cheng C; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, China.
Li S; Department of Human Anatomy, School of Medicine, Jinan University, Guangzhou, 510632, China.
Wu Y; State Key Laboratory of Virology, Wuhan Institute of Virology, Center for Biosafet Mega-Science, Chinese Academy of Sciences, Wuhan, 430071, China.
Liu Z; Key Laboratory for Biobased Materials and Energy of Ministry of Education, College of Materials and Energy, South China Agricultural University, Guangzhou, 510642, China.
Liu M; Key Laboratory for Biobased Materials and Energy of Ministry of Education, College of Materials and Energy, South China Agricultural University, Guangzhou, 510642, China.
Chen J; Guangdong Provincial Key Laboratory of Veterinary Pharmaceutics Development and Safety Evaluation, College of Veterinary Medicine, South China Agricultural University, Guangzhou, 510642, China.
Zhong Q; Key Laboratory for Biobased Materials and Energy of Ministry of Education, College of Materials and Energy, South China Agricultural University, Guangzhou, 510642, China.
Zhang X; Key Laboratory for Biobased Materials and Energy of Ministry of Education, College of Materials and Energy, South China Agricultural University, Guangzhou, 510642, China.
Liu S; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, China; State Key Laboratory of Organ Failure Research, Guangdong Provincial Institute of Nephrology, Southern Medical University, Guangzhou, 510515, China. Electronic address: .
Song G; Key Laboratory for Biobased Materials and Energy of Ministry of Education, College of Materials and Energy, South China Agricultural University, Guangzhou, 510642, China. Electronic address: .
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Źródło :
European journal of medicinal chemistry [Eur J Med Chem] 2021 Apr 05; Vol. 215, pp. 113242. Date of Electronic Publication: 2021 Feb 08.
Typ publikacji :
Journal Article
MeSH Terms :
Antiviral Agents/*pharmacology
SARS-CoV-2/*drug effects
Saponins/*pharmacology
Triterpenes/*pharmacology
Virus Internalization/*drug effects
Animals ; Antiviral Agents/chemical synthesis ; Antiviral Agents/metabolism ; Chlorocebus aethiops ; Drug Discovery ; HEK293 Cells ; Humans ; Microbial Sensitivity Tests ; Molecular Structure ; Protein Binding ; Protein Subunits/metabolism ; Saponins/chemical synthesis ; Saponins/metabolism ; Spike Glycoprotein, Coronavirus/metabolism ; Structure-Activity Relationship ; Triterpenes/chemical synthesis ; Triterpenes/metabolism ; Vero Cells
Czasopismo naukowe
Tytuł :
Two new dammarane-type triterpenoids from the stems and leaves of Panax notoginseng .
Autorzy :
Yang CK; College of Agriculture and Biotechnology, Yunnan Agricultural University, Kunming 650201, China.; Research & Development center for Functional products, Yunnan Agricultural University, Kunming 650201, China.; Kunming Kangren Biotechnology CO., Ltd, Kunming 650033, China.
Xiong J; College of Agriculture and Biotechnology, Yunnan Agricultural University, Kunming 650201, China.; Research & Development center for Functional products, Yunnan Agricultural University, Kunming 650201, China.; Kunming Kangren Biotechnology CO., Ltd, Kunming 650033, China.
Shen Y; College of Agriculture and Biotechnology, Yunnan Agricultural University, Kunming 650201, China.; Research & Development center for Functional products, Yunnan Agricultural University, Kunming 650201, China.; Kunming Kangren Biotechnology CO., Ltd, Kunming 650033, China.
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Źródło :
Journal of Asian natural products research [J Asian Nat Prod Res] 2021 Apr; Vol. 23 (4), pp. 341-347. Date of Electronic Publication: 2020 Mar 03.
Typ publikacji :
Journal Article
MeSH Terms :
Panax*
Panax notoginseng*
Saponins*
Triterpenes*
Molecular Structure ; Plant Leaves
Czasopismo naukowe
Tytuł :
Dammarane-type triterpenoid saponins from Salvia russellii Benth.
Autorzy :
Hafez Ghoran S; Medicinal and Natural Products Chemistry Research Center, Shiraz University of Medical Sciences, Shiraz, 71348-53734, Iran; Department of Chemistry, Faculty of Basic Sciences, Golestan University, Gorgan, 49138-15759, Iran.
Firuzi O; Medicinal and Natural Products Chemistry Research Center, Shiraz University of Medical Sciences, Shiraz, 71348-53734, Iran.
Asadollahi M; Medicinal and Natural Products Chemistry Research Center, Shiraz University of Medical Sciences, Shiraz, 71348-53734, Iran.
Stuppner H; Institute of Pharmacy, Pharmacognosy, CMBI, University of Innsbruck, Innrain 80-82, 6020, Innsbruck, Austria.
Alilou M; Institute of Pharmacy, Pharmacognosy, CMBI, University of Innsbruck, Innrain 80-82, 6020, Innsbruck, Austria.
Jassbi AR; Medicinal and Natural Products Chemistry Research Center, Shiraz University of Medical Sciences, Shiraz, 71348-53734, Iran. Electronic address: .
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Źródło :
Phytochemistry [Phytochemistry] 2021 Apr; Vol. 184, pp. 112653. Date of Electronic Publication: 2021 Jan 29.
Typ publikacji :
Journal Article
MeSH Terms :
Oleanolic Acid*
Salvia*
Saponins*
Triterpenes*/pharmacology
Animals ; Mice ; Molecular Structure
Czasopismo naukowe
Tytuł :
Friedelin exhibits antidiabetic effect in diabetic rats via modulation of glucose metabolism in liver and muscle.
Autorzy :
Sunil C; Division of Ethnopharmacology, Entomology Research Institute, Loyola College, Chennai, 600034, India; Food Science and Technology Programme, Beijing Normal University-Hong Kong Baptist University United International College, Zhuhai, Guangdong, 519087, China. Electronic address: .
Irudayaraj SS; Division of Ethnopharmacology, Entomology Research Institute, Loyola College, Chennai, 600034, India; St. Xavier's College, Maharo, Dumka, 814110, Jharkhand, India.
Duraipandiyan V; Division of Ethnopharmacology, Entomology Research Institute, Loyola College, Chennai, 600034, India. Electronic address: .
Alrashood ST; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh, 11451, Saudi Arabia.
Alharbi SA; Department of Botany and Microbiology, College of Science, King Saudi University, P.O Box 2455, Riyadh, 11451, Saudi Arabia.
Ignacimuthu S; Division of Ethnopharmacology, Entomology Research Institute, Loyola College, Chennai, 600034, India.
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Źródło :
Journal of ethnopharmacology [J Ethnopharmacol] 2021 Mar 25; Vol. 268, pp. 113659. Date of Electronic Publication: 2020 Dec 01.
Typ publikacji :
Journal Article
MeSH Terms :
Diabetes Mellitus, Experimental/*drug therapy
Glucose/*antagonists & inhibitors
Hypoglycemic Agents/*therapeutic use
Liver/*drug effects
Muscle, Skeletal/*drug effects
Triterpenes/*therapeutic use
Animals ; Diabetes Mellitus, Experimental/metabolism ; Dose-Response Relationship, Drug ; Drugs, Chinese Herbal/isolation & purification ; Drugs, Chinese Herbal/pharmacology ; Drugs, Chinese Herbal/therapeutic use ; Glucose/metabolism ; Hypoglycemic Agents/isolation & purification ; Hypoglycemic Agents/pharmacology ; Liver/metabolism ; Male ; Muscle, Skeletal/metabolism ; Rats ; Rats, Wistar ; Triterpenes/isolation & purification ; Triterpenes/pharmacology
Czasopismo naukowe
Tytuł :
Triterpenoids from the genus Gynostemma: Chemistry and pharmacological activities.
Autorzy :
Nguyen NH; Faculty of Pharmacy, PHENIKAA University, Hanoi, 12116, Viet Nam; PHENIKAA Research and Technology Institute (PRATI), A&A Green Phoenix Group JSC, No. 167 Hoang Ngan, Trung Hoa, Cau Giay, Hanoi, 11313, Viet Nam.
Ha TKQ; College of Natural Sciences, Cantho University, Campus II, Cantho City, Viet Nam.
Yang JL; Key Laboratory of Chemistry of Northwestern Plant Resources of CAS and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, 730000, PR China.
Pham HTT; Department of Botany, Hanoi University of Pharmacy, Hanoi, 100000, Viet Nam.
Oh WK; Korea Bioactive Natural Material Bank, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, 08826, Republic of Korea. Electronic address: .
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Źródło :
Journal of ethnopharmacology [J Ethnopharmacol] 2021 Mar 25; Vol. 268, pp. 113574. Date of Electronic Publication: 2020 Nov 10.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Gynostemma*
Ethnopharmacology/*methods
Medicine, Traditional/*methods
Phytochemicals/*therapeutic use
Plant Extracts/*therapeutic use
Triterpenes/*therapeutic use
Animals ; Antineoplastic Agents, Phytogenic/chemistry ; Antineoplastic Agents, Phytogenic/isolation & purification ; Antineoplastic Agents, Phytogenic/therapeutic use ; Cardiotonic Agents/chemistry ; Cardiotonic Agents/isolation & purification ; Cardiotonic Agents/therapeutic use ; Humans ; Phytochemicals/chemistry ; Phytochemicals/isolation & purification ; Plant Extracts/chemistry ; Plant Extracts/isolation & purification ; Triterpenes/chemistry ; Triterpenes/isolation & purification
Czasopismo naukowe
Tytuł :
Bioguided identification of pentacyclic triterpenoids as anti-inflammatory bioactive constituents of Ocimum gratissimum extract.
Autorzy :
Dzoyem JP; Department of Biochemistry, Faculty of Science, University of Dschang, P. O. Box 67, Dschang, Cameroon; Institute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, Rue Michel-Servet 1, 1211, Geneva, Switzerland; School of Pharmaceutical Sciences, University of Geneva, Rue Michel-Servet 1, 1211, Geneva, Switzerland. Electronic address: .
Nganteng DND; Department of Organic Chemistry, Faculty of Sciences, University of Yaoundé I., P.O. Box 812, Yaoundé, Cameroon. Electronic address: .
Melong R; Department of Fundamental Science, Higher Technical Teacher Training College, University of Bamenda, P.O. Box. 39, Bambili, Cameroon. Electronic address: .
Wafo P; Department of Chemistry, Higher Teachers' Training College, University of Yaoundé I., P.O. Box 47, Yaoundé, Cameroon. Electronic address: .
Ngadjui B; Department of Organic Chemistry, Faculty of Sciences, University of Yaoundé I., P.O. Box 812, Yaoundé, Cameroon. Electronic address: .
Allémann E; Institute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, Rue Michel-Servet 1, 1211, Geneva, Switzerland; School of Pharmaceutical Sciences, University of Geneva, Rue Michel-Servet 1, 1211, Geneva, Switzerland. Electronic address: .
Delie F; Institute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, Rue Michel-Servet 1, 1211, Geneva, Switzerland; School of Pharmaceutical Sciences, University of Geneva, Rue Michel-Servet 1, 1211, Geneva, Switzerland. Electronic address: .
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Źródło :
Journal of ethnopharmacology [J Ethnopharmacol] 2021 Mar 25; Vol. 268, pp. 113637. Date of Electronic Publication: 2020 Nov 29.
Typ publikacji :
Journal Article
MeSH Terms :
Ocimum*
Anti-Inflammatory Agents/*isolation & purification
Inflammation Mediators/*antagonists & inhibitors
Pentacyclic Triterpenes/*isolation & purification
Phytochemicals/*isolation & purification
Plant Extracts/*isolation & purification
Animals ; Anti-Inflammatory Agents/pharmacology ; Cell Survival/drug effects ; Cell Survival/physiology ; Dose-Response Relationship, Drug ; Humans ; Inflammation Mediators/metabolism ; Mice ; Pentacyclic Triterpenes/pharmacology ; Phytochemicals/pharmacology ; Plant Extracts/pharmacology ; RAW 264.7 Cells
Czasopismo naukowe
Tytuł :
A Carrier-Free Folate Receptor-Targeted Ursolic Acid/Methotrexate Nanodelivery System for Synergetic Anticancer Therapy.
Autorzy :
Lan JS; Experiment Center of Teaching and Learning, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, People's Republic of China.; School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, People's Republic of China.
Qin YH; School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, People's Republic of China.
Liu L; School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, People's Republic of China.
Zeng RF; School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, People's Republic of China.
Yang Y; Science and Technology Experimental Center, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, People's Republic of China.
Wang K; Science and Technology Experimental Center, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, People's Republic of China.
Ding Y; Experiment Center of Teaching and Learning, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, People's Republic of China.; School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, People's Republic of China.
Zhang T; Experiment Center of Teaching and Learning, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, People's Republic of China.; School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, People's Republic of China.
Ho RJY; Department of Pharmaceutics, University of Washington, Seattle, WA, 98195, USA.
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Źródło :
International journal of nanomedicine [Int J Nanomedicine] 2021 Mar 03; Vol. 16, pp. 1775-1787. Date of Electronic Publication: 2021 Mar 03 (Print Publication: 2021).
Typ publikacji :
Journal Article
MeSH Terms :
Drug Delivery Systems*
Antineoplastic Agents/*pharmacology
Drug Carriers/*chemistry
Folate Receptors, GPI-Anchored/*metabolism
Methotrexate/*pharmacology
Nanoparticles/*chemistry
Triterpenes/*pharmacology
Animals ; Antineoplastic Agents/administration & dosage ; Cell Death/drug effects ; Cell Survival/drug effects ; Drug Liberation ; Drug Synergism ; Endocytosis/drug effects ; Female ; Folic Acid/chemistry ; Humans ; MCF-7 Cells ; Methotrexate/administration & dosage ; Methotrexate/chemistry ; Mice, Nude ; Nanoparticles/ultrastructure ; Rats, Wistar ; Triterpenes/administration & dosage ; Triterpenes/chemistry
Czasopismo naukowe
Tytuł :
Pentacyclic Triterpene Profile and Its Biosynthetic Pathway in Cecropia telenitida as a Prospective Dietary Supplement.
Autorzy :
Gutiérrez G; Department of Pharmaceutical Sciences, School of Natural Sciences, Universidad Icesi, Cali 760031, Colombia.
Valencia LM; Department of Pharmaceutical Sciences, School of Natural Sciences, Universidad Icesi, Cali 760031, Colombia.
Giraldo-Dávila D; Escuela de Química, Universidad Industrial de Santander, Bucaramanga 680003, Colombia.
Combariza MY; Escuela de Química, Universidad Industrial de Santander, Bucaramanga 680003, Colombia.
Galeano E; Productos Naturales Marinos, Departamento de Farmacia, Facultad de Ciencias Farmacéuticas y Alimentarias, Universidad de Antioquia, UdeA, Calle 70 # 52-21, Laboratorio 2-131, Medellín 050010, Colombia.
Balcazar N; Department of Physiology and Biochemistry, School of Medicine, Universidad de Antioquia, Carrera 51D Nº 62-29, Medellin 050010, Colombia.; GENMOL Group, Sede de Investigación Universitaria, Universidad de Antioquia, Calle 62 # 52-59, Medellín 050010, Colombia.
Panay AJ; Independent Researcher, Calle 28 # 86-70 Apt 712, Cali 760031, Colombia.
Jerez AM; Department of Biomedical Sciences, School of Health, Universidad Icesi, Cali 760031, Colombia.
Montoya G; Department of Pharmaceutical Sciences, School of Natural Sciences, Universidad Icesi, Cali 760031, Colombia.; Center for Specialized and Biotechnological Natural Ingredients (CINEB), School of Natural Sciences, Universidad Icesi, Cali 760031, Colombia.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Feb 18; Vol. 26 (4). Date of Electronic Publication: 2021 Feb 18.
Typ publikacji :
Journal Article
MeSH Terms :
Biosynthetic Pathways*
Dietary Supplements*
Cecropia Plant/*chemistry
Pentacyclic Triterpenes/*metabolism
Animals ; Cell Death/drug effects ; Cell Line ; Cell Survival/drug effects ; Chemical Fractionation ; Chromatography, High Pressure Liquid ; Humans ; Magnetic Resonance Spectroscopy ; Mice ; Pentacyclic Triterpenes/chemistry ; Pentacyclic Triterpenes/pharmacology
Czasopismo naukowe
Tytuł :
Anti-Inflammatory, Antidiabetic Properties and In Silico Modeling of Cucurbitane-Type Triterpene Glycosides from Fruits of an Indian Cultivar of Momordica charantia L.
Autorzy :
Perera WH; Vegetable and Fruit Improvement Center, Department of Horticultural Sciences, Texas A&M University, 1500 Research Parkway, Suite A120, College Station, TX 77843, USA.
Shivanagoudra SR; Vegetable and Fruit Improvement Center, Department of Horticultural Sciences, Texas A&M University, 1500 Research Parkway, Suite A120, College Station, TX 77843, USA.
Pérez JL; Vegetable and Fruit Improvement Center, Department of Horticultural Sciences, Texas A&M University, 1500 Research Parkway, Suite A120, College Station, TX 77843, USA.
Kim DM; Department of Nutrition, Texas A&M University, College Station, TX 77843, USA.
Sun Y; Department of Nutrition, Texas A&M University, College Station, TX 77843, USA.
K Jayaprakasha G; Vegetable and Fruit Improvement Center, Department of Horticultural Sciences, Texas A&M University, 1500 Research Parkway, Suite A120, College Station, TX 77843, USA.
S Patil B; Vegetable and Fruit Improvement Center, Department of Horticultural Sciences, Texas A&M University, 1500 Research Parkway, Suite A120, College Station, TX 77843, USA.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Feb 16; Vol. 26 (4). Date of Electronic Publication: 2021 Feb 16.
Typ publikacji :
Journal Article
MeSH Terms :
Computer Simulation*
Anti-Inflammatory Agents/*pharmacology
Fruit/*chemistry
Glycosides/*chemistry
Glycosides/*pharmacology
Hypoglycemic Agents/*pharmacology
Momordica charantia/*chemistry
Triterpenes/*chemistry
Triterpenes/*pharmacology
Animals ; Anti-Inflammatory Agents/chemistry ; Biological Assay ; Carbon-13 Magnetic Resonance Spectroscopy ; Glycosides/isolation & purification ; Hypoglycemic Agents/chemistry ; Ligands ; Mice ; Molecular Conformation ; Molecular Docking Simulation ; Proton Magnetic Resonance Spectroscopy ; RAW 264.7 Cells ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Triterpenes/isolation & purification ; alpha-Amylases/chemistry ; alpha-Amylases/metabolism ; alpha-Glucosidases/chemistry ; alpha-Glucosidases/metabolism
Czasopismo naukowe
Tytuł :
Antioxidant activity of α and β -amyrin isolated from Myrcianthes pungens leaves.
Autorzy :
Karen Cardoso B; Postgraduate Program in Biotechnology Applied to Agriculture, Paranaense University (UNIPAR), Umuarama, Paraná, Brazil.
Line Marko de Oliveira H; Postgraduate Program in Biotechnology Applied to Agriculture, Paranaense University (UNIPAR), Umuarama, Paraná, Brazil.
Zonta Melo U; Department of Chemistry, State University of Maringá (UEM), Maringá, Paraná, Brazil.
Mariano Fernandez CM; Postgraduate Program in Pharmaceutical Sciences, State University of Maringá (UEM), Maringá, Paraná, Brazil.
Franco de Araújo Almeida Campo C; Postgraduate Programs in Clean Technologies, Cesumar University (UNI-Cesumar), Maringá, Paraná, Brazil.
Gonçalves JE; Postgraduate Programs in Clean Technologies, Cesumar University (UNI-Cesumar), Maringá, Paraná, Brazil.; Cesumar Institute of Science, Technology and Innovation - ICETI, Maringá, Paraná, Brazil.
Laverde A Jr; Cesumar Institute of Science, Technology and Innovation - ICETI, Federal Technological University of Paraná (COLIQ), Londrina, Paraná, Brazil.
Barion Romagnolo M; Chemistry Department, Federal Technological University of Parana (UTFPR), Londrina, Paraná, Brazil.
Andrea Linde G; Postgraduate Program in Biotechnology Applied to Agriculture, Paranaense University (UNIPAR), Umuarama, Paraná, Brazil.
Cristiani Gazim Z; Postgraduate Program in Biotechnology Applied to Agriculture, Paranaense University (UNIPAR), Umuarama, Paraná, Brazil.
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Źródło :
Natural product research [Nat Prod Res] 2020 Jun; Vol. 34 (12), pp. 1777-1781. Date of Electronic Publication: 2018 Nov 22.
Typ publikacji :
Journal Article
MeSH Terms :
Antioxidants/*isolation & purification
Myrtaceae/*chemistry
Oleanolic Acid/*analogs & derivatives
Pentacyclic Triterpenes/*isolation & purification
Antioxidants/chemistry ; Antioxidants/pharmacology ; Brazil ; Gas Chromatography-Mass Spectrometry/methods ; Oleanolic Acid/isolation & purification ; Oleanolic Acid/pharmacology ; Pentacyclic Triterpenes/chemistry ; Pentacyclic Triterpenes/pharmacology ; Plant Extracts/chemistry ; Plant Extracts/pharmacology ; Plant Leaves/chemistry ; Triterpenes/isolation & purification
Czasopismo naukowe
Tytuł :
Triterpenoid saponins from Ilex cornuta protect H9c2 cardiomyocytes against H2O2-induced apoptosis by modulating Ezh2 phosphorylation.
Autorzy :
Yu D; Department of Pharmacy, Children's Hospital of Soochow University, Suzhou, 215000, China.
Zhu Z; Department of Pharmacy, Children's Hospital of Soochow University, Suzhou, 215000, China.
Wang M; Department of Pharmacy, Children's Hospital of Soochow University, Suzhou, 215000, China.
Ding X; Department of Pharmacy, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou, 215000, China.
Gui H; Department of Pharmacy, Children's Hospital of Soochow University, Suzhou, 215000, China.
Ma J; Department of Pharmacy, Children's Hospital of Soochow University, Suzhou, 215000, China.
Yan Y; Department of Pharmacy, Children's Hospital of Soochow University, Suzhou, 215000, China.
Li G; Institute of Pediatric Research, Children's Hospital of Soochow University, Suzhou, 215000, China.
Xu Q; College of Pharmaceutical Science, Soochow University, Suzhou, 215123, China.
Wang W; Department of Pharmacy, Children's Hospital of Soochow University, Suzhou, 215000, China. Electronic address: .
Mao C; Department of Pharmacy, Children's Hospital of Soochow University, Suzhou, 215000, China. Electronic address: .
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Źródło :
Journal of ethnopharmacology [J Ethnopharmacol] 2021 Apr 06; Vol. 269, pp. 113691. Date of Electronic Publication: 2020 Dec 13.
Typ publikacji :
Journal Article
MeSH Terms :
Ilex*
Enhancer of Zeste Homolog 2 Protein/*metabolism
Hydrogen Peroxide/*toxicity
Myocytes, Cardiac/*metabolism
Saponins/*pharmacology
Triterpenes/*pharmacology
Animals ; Apoptosis/drug effects ; Apoptosis/physiology ; Cardiotonic Agents/isolation & purification ; Cardiotonic Agents/pharmacology ; Cell Line ; Myocytes, Cardiac/drug effects ; Phosphorylation/drug effects ; Phosphorylation/physiology ; Rats ; Saponins/isolation & purification ; Triterpenes/isolation & purification
Czasopismo naukowe

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