Temat: "Triterpenes" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Simultaneous identification and quantification of pentacyclic triterpenoids and phenolic compounds from the leaves of Boswellia serrata using LC-MS/MS tandem mass spectrometry.
Autorzy:: Trivedi MK; Trivedi Global, Inc., Henderson, NV, USA.
Branton A; Trivedi Global, Inc., Henderson, NV, USA.
Trivedi D; Trivedi Global, Inc., Henderson, NV, USA.
Sharma T; Sai Life Sciences Ltd., Hyderabad, India.
Mondal S; Trivedi Science Research Laboratory Pvt. Ltd., Thane, Maharashtra, India.
Jana S; Trivedi Science Research Laboratory Pvt. Ltd., Thane, Maharashtra, India. .; Pokaż więcej
Źródło:: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry [Anal Sci] 2023 Oct; Vol. 39 (10), pp. 1741-1756. Date of Electronic Publication: 2023 Jun 30.
Typ publikacji:: Journal Article
MeSH Terms:: Boswellia*/chemistry
Triterpenes*/analysis
Chromatography, Liquid/methods ; Tandem Mass Spectrometry/methods ; Pentacyclic Triterpenes/analysis ; Plant Extracts/chemistry ; Chromatography, High Pressure Liquid/methods

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Skocz do pozycji: 2.

Tytuł:: Discovery, structural optimization, and anti-tumor bioactivity evaluations of betulinic acid derivatives as a new type of RORγ antagonists.
Autorzy:: Mei L; School of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing, 210023, China; Drug Discovery and Development Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai, 201203, China.
Xu L; Drug Discovery and Development Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai, 201203, China; The First Affiliated Hospital of USTC (Anhui Provincial Hospital), Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China; Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, 393 Middle Huaxia Road, Shanghai, 201210, China; School of Life Science and Technology, ShanghaiTech University, Shanghai, 201210, China.
Wu S; Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, 393 Middle Huaxia Road, Shanghai, 201210, China; School of Life Science and Technology, ShanghaiTech University, Shanghai, 201210, China.
Wang Y; Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, 393 Middle Huaxia Road, Shanghai, 201210, China.
Xu C; Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, 393 Middle Huaxia Road, Shanghai, 201210, China; School of Life Science and Technology, ShanghaiTech University, Shanghai, 201210, China.
Wang L; Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, 393 Middle Huaxia Road, Shanghai, 201210, China; School of Life Science and Technology, ShanghaiTech University, Shanghai, 201210, China.
Zhang X; China Suzhou Institute of Drug Innovation, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Suzhou, Jiangsu, 215123, China.
Yu C; Drug Discovery and Development Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai, 201203, China.
Jiang H; School of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing, 210023, China; Drug Discovery and Development Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai, 201203, China; Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, 393 Middle Huaxia Road, Shanghai, 201210, China; School of Life Science and Technology, ShanghaiTech University, Shanghai, 201210, China.
Zhang X; Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, 393 Middle Huaxia Road, Shanghai, 201210, China. Electronic address: .
Bai F; Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, 393 Middle Huaxia Road, Shanghai, 201210, China; School of Life Science and Technology, ShanghaiTech University, Shanghai, 201210, China; Shanghai Clinical Research and Trial Center, Shanghai, 201210, China. Electronic address: .
Xie C; Drug Discovery and Development Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai, 201203, China; Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, 393 Middle Huaxia Road, Shanghai, 201210, China; School of Life Science and Technology, ShanghaiTech University, Shanghai, 201210, China; Lingang Laboratory, Shanghai, 200031, China. Electronic address: .; Pokaż więcej
Źródło:: European journal of medicinal chemistry [Eur J Med Chem] 2023 Sep 05; Vol. 257, pp. 115472. Date of Electronic Publication: 2023 May 18.
Typ publikacji:: Journal Article
MeSH Terms:: Triterpenes*/pharmacology
Triterpenes*/chemistry
Pancreatic Neoplasms*
Humans ; Pentacyclic Triterpenes/pharmacology ; Betulinic Acid ; Apoptosis ; Cell Line, Tumor

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Skocz do pozycji: 3.

Tytuł:: The discovery of the new mechanism: Celastrol improves spinal cord injury by increasing cAMP through VIP-ADCYAP1R1-GNAS pathway.
Autorzy:: Li C; Department of Orthopedics, International Science and Technology Cooperation Base of Spinal Cord Injury, Tianjin Key Laboratory of Spine and Spinal Cord Injury, Tianjin Medical University General Hospital, 154 Anshan Road, Heping District, Tianjin 300052, China.
Shen W; Department of Orthopedics, International Science and Technology Cooperation Base of Spinal Cord Injury, Tianjin Key Laboratory of Spine and Spinal Cord Injury, Tianjin Medical University General Hospital, 154 Anshan Road, Heping District, Tianjin 300052, China; Spine Surgery Department of the Second Hospital, Cheeloo College of Medicine, Shandong University, 247 Beiyuan Street, Jinan, Shandong 250033, China.
Xu Z; Department of Orthopedics, International Science and Technology Cooperation Base of Spinal Cord Injury, Tianjin Key Laboratory of Spine and Spinal Cord Injury, Tianjin Medical University General Hospital, 154 Anshan Road, Heping District, Tianjin 300052, China.
Li C; Department of Orthopedics, International Science and Technology Cooperation Base of Spinal Cord Injury, Tianjin Key Laboratory of Spine and Spinal Cord Injury, Tianjin Medical University General Hospital, 154 Anshan Road, Heping District, Tianjin 300052, China.
Liu Q; Department of Orthopedics, International Science and Technology Cooperation Base of Spinal Cord Injury, Tianjin Key Laboratory of Spine and Spinal Cord Injury, Tianjin Medical University General Hospital, 154 Anshan Road, Heping District, Tianjin 300052, China.
Pang Y; Department of Orthopedics, International Science and Technology Cooperation Base of Spinal Cord Injury, Tianjin Key Laboratory of Spine and Spinal Cord Injury, Tianjin Medical University General Hospital, 154 Anshan Road, Heping District, Tianjin 300052, China.
Li J; Department of Orthopedics, International Science and Technology Cooperation Base of Spinal Cord Injury, Tianjin Key Laboratory of Spine and Spinal Cord Injury, Tianjin Medical University General Hospital, 154 Anshan Road, Heping District, Tianjin 300052, China.
Wang X; Department of Orthopedics, International Science and Technology Cooperation Base of Spinal Cord Injury, Tianjin Key Laboratory of Spine and Spinal Cord Injury, Tianjin Medical University General Hospital, 154 Anshan Road, Heping District, Tianjin 300052, China.
Wang Z; Department of Orthopedics, International Science and Technology Cooperation Base of Spinal Cord Injury, Tianjin Key Laboratory of Spine and Spinal Cord Injury, Tianjin Medical University General Hospital, 154 Anshan Road, Heping District, Tianjin 300052, China.
Feng S; Department of Orthopedics, International Science and Technology Cooperation Base of Spinal Cord Injury, Tianjin Key Laboratory of Spine and Spinal Cord Injury, Tianjin Medical University General Hospital, 154 Anshan Road, Heping District, Tianjin 300052, China; Spine Surgery Department of the Second Hospital, Cheeloo College of Medicine, Shandong University, 247 Beiyuan Street, Jinan, Shandong 250033, China; Orthopedic Research Center of Shandong University &Advanced Medical Research Institute, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250063, China. Electronic address: .; Pokaż więcej
Źródło:: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2023 Sep; Vol. 165, pp. 115250. Date of Electronic Publication: 2023 Jul 31.
Typ publikacji:: Journal Article
MeSH Terms:: Spinal Cord Injuries*/drug therapy
Triterpenes*/pharmacology
Triterpenes*/therapeutic use
Anti-Inflammatory Agents/pharmacology ; Apoptosis ; Chromogranins/pharmacology ; Chromogranins/therapeutic use ; GTP-Binding Protein alpha Subunits, Gs/pharmacology ; GTP-Binding Protein alpha Subunits, Gs/therapeutic use ; Pentacyclic Triterpenes/pharmacology ; Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I ; Spinal Cord ; Animals

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Skocz do pozycji: 4.

Tytuł:: Development of novel celastrol-ligustrazine hybrids as potent peroxiredoxin 1 inhibitors against lung cancer.
Autorzy:: Bai Y; School of Medicine, Anhui University of Science and Technology, Huainan, 232001, China; Anhui Occupational Health and Safety Engineering Laboratory, Huainan, 232001, China.
Liang C; School of Medicine, Anhui University of Science and Technology, Huainan, 232001, China; Anhui Occupational Health and Safety Engineering Laboratory, Huainan, 232001, China.
Zhou J; School of Medicine, Anhui University of Science and Technology, Huainan, 232001, China; Anhui Occupational Health and Safety Engineering Laboratory, Huainan, 232001, China.
Liu Y; School of Medicine, Anhui University of Science and Technology, Huainan, 232001, China; Anhui Occupational Health and Safety Engineering Laboratory, Huainan, 232001, China.
Wang F; School of Medicine, Anhui University of Science and Technology, Huainan, 232001, China.
Gao J; School of Medicine, Anhui University of Science and Technology, Huainan, 232001, China.
Wu J; School of Medicine, Anhui University of Science and Technology, Huainan, 232001, China; Anhui Occupational Health and Safety Engineering Laboratory, Huainan, 232001, China; Key Laboratory of Industrial Dust Deep Reduction and Occupational Health and Safety of Anhui Higher Education Institute, Huainan, 232001, China; Key Laboratory of Industrial Dust Prevention and Control & Occupational Safety and Health of the Ministry of Education, Anhui University of Science and Technology, Huainan, 232001, China.
Hu D; School of Medicine, Anhui University of Science and Technology, Huainan, 232001, China; Anhui Occupational Health and Safety Engineering Laboratory, Huainan, 232001, China; Key Laboratory of Industrial Dust Deep Reduction and Occupational Health and Safety of Anhui Higher Education Institute, Huainan, 232001, China; Key Laboratory of Industrial Dust Prevention and Control & Occupational Safety and Health of the Ministry of Education, Anhui University of Science and Technology, Huainan, 232001, China. Electronic address: .; Pokaż więcej
Źródło:: European journal of medicinal chemistry [Eur J Med Chem] 2023 Nov 05; Vol. 259, pp. 115656. Date of Electronic Publication: 2023 Jul 17.
Typ publikacji:: Journal Article
MeSH Terms:: Antineoplastic Agents*/pharmacology
Lung Neoplasms*/drug therapy
Triterpenes*/pharmacology
Humans ; Apoptosis ; Cell Line, Tumor ; Cell Proliferation ; Pentacyclic Triterpenes/pharmacology ; Reactive Oxygen Species/metabolism ; Peroxiredoxins/antagonists & inhibitors

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Skocz do pozycji: 5.

Tytuł:: Discovery of unique CYP716C oxidase involved in pentacyclic triterpene biosynthesis from Camptotheca acuminata.
Autorzy:: Pu X; College of Science, Sichuan Agricultural University, Ya'an, 625104, PR China. Electronic address: .
Chen M; College of Science, Sichuan Agricultural University, Ya'an, 625104, PR China.
Lei M; College of Science, Sichuan Agricultural University, Ya'an, 625104, PR China.
Lin X; College of Science, Sichuan Agricultural University, Ya'an, 625104, PR China.
Zhang J; College of Science, Sichuan Agricultural University, Ya'an, 625104, PR China.
Ai Z; College of Science, Sichuan Agricultural University, Ya'an, 625104, PR China.
He J; College of Science, Sichuan Agricultural University, Ya'an, 625104, PR China.
Liu Y; College of Science, Sichuan Agricultural University, Ya'an, 625104, PR China.
Yang S; College of Science, Sichuan Agricultural University, Ya'an, 625104, PR China.
Wang H; College of Science, Sichuan Agricultural University, Ya'an, 625104, PR China.
Liao J; College of Life Science, Sichuan Agricultural University, Ya'an, 625104, PR China.
Zhang L; College of Science, Sichuan Agricultural University, Ya'an, 625104, PR China.
Huang Q; College of Science, Sichuan Agricultural University, Ya'an, 625104, PR China. Electronic address: .; Pokaż więcej
Źródło:: Plant physiology and biochemistry : PPB [Plant Physiol Biochem] 2023 Sep; Vol. 202, pp. 107929. Date of Electronic Publication: 2023 Aug 02.
Typ publikacji:: Journal Article
MeSH Terms:: Camptotheca*/metabolism
Triterpenes*/metabolism
Oxidoreductases ; Pentacyclic Triterpenes

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Skocz do pozycji: 6.

Tytuł:: Pentacyclic Triterpenes from Olive Leaves Formulated in Microemulsion: Characterization and Role in De Novo Lipogenesis in HepG2 Cells.
Autorzy:: Vasarri M; Department of Experimental and Clinical Biomedical Sciences, University of Florence, Viale Morgagni 50, 50134 Florence, Italy.; Department of Chemistry, University of Florence, Via U. Schiff 6, 50519 Sesto Fiorentino, Italy.
Degl'Innocenti D; Department of Experimental and Clinical Biomedical Sciences, University of Florence, Viale Morgagni 50, 50134 Florence, Italy.
Albonetti L; Department of Chemistry, University of Florence, Via U. Schiff 6, 50519 Sesto Fiorentino, Italy.
Bilia AR; Department of Chemistry, University of Florence, Via U. Schiff 6, 50519 Sesto Fiorentino, Italy.
Bergonzi MC; Department of Chemistry, University of Florence, Via U. Schiff 6, 50519 Sesto Fiorentino, Italy.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Jul 28; Vol. 24 (15). Date of Electronic Publication: 2023 Jul 28.
Typ publikacji:: Journal Article
MeSH Terms:: Olea*
Carcinoma, Hepatocellular*/drug therapy
Liver Neoplasms*/drug therapy
Triterpenes*/pharmacology
Triterpenes*/chemistry
Humans ; Pentacyclic Triterpenes ; Lipogenesis ; Hep G2 Cells ; Emulsions/chemistry ; Membranes, Artificial ; Plant Leaves ; Lipids

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Skocz do pozycji: 7.

Tytuł:: A Triterpenoid Lupeol as an Antioxidant and Anti-Neuroinflammatory Agent: Impacts on Oxidative Stress in Alzheimer's Disease.
Autorzy:: Park JS; Division of Life Sciences and Applied Life Science (BK21 Four), College of Natural Science, Gyeongsang National University, Jinju 52828, Republic of Korea.
Rehman IU; Division of Life Sciences and Applied Life Science (BK21 Four), College of Natural Science, Gyeongsang National University, Jinju 52828, Republic of Korea.
Choe K; Division of Life Sciences and Applied Life Science (BK21 Four), College of Natural Science, Gyeongsang National University, Jinju 52828, Republic of Korea.; Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience (MHeNs), Maastricht University, 6229 ER Maastricht, The Netherlands.
Ahmad R; Division of Life Sciences and Applied Life Science (BK21 Four), College of Natural Science, Gyeongsang National University, Jinju 52828, Republic of Korea.
Lee HJ; Division of Life Sciences and Applied Life Science (BK21 Four), College of Natural Science, Gyeongsang National University, Jinju 52828, Republic of Korea.
Kim MO; Division of Life Sciences and Applied Life Science (BK21 Four), College of Natural Science, Gyeongsang National University, Jinju 52828, Republic of Korea.; Alz-Dementia Korea Co., Jinju 52828, Republic of Korea.; Pokaż więcej
Źródło:: Nutrients [Nutrients] 2023 Jul 07; Vol. 15 (13). Date of Electronic Publication: 2023 Jul 07.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Alzheimer Disease*/metabolism
Neurodegenerative Diseases*/drug therapy
Triterpenes*/pharmacology
Triterpenes*/therapeutic use
Humans ; Aged ; Antioxidants/pharmacology ; Antioxidants/therapeutic use ; Antioxidants/metabolism ; Reactive Oxygen Species/metabolism ; Molecular Docking Simulation ; Oxidative Stress ; Pentacyclic Triterpenes/pharmacology ; Pentacyclic Triterpenes/therapeutic use

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Skocz do pozycji: 8.

Tytuł:: Discovery of Novel Pentacyclic Triterpene Acid Amide Derivatives as Excellent Antimicrobial Agents Dependent on Generation of Reactive Oxygen Species.
Autorzy:: Yang Y; National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for R&D of Fine Chemicals of Guizhou University, Guiyang 550025, China.
Chen K; National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for R&D of Fine Chemicals of Guizhou University, Guiyang 550025, China.
Wang G; National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for R&D of Fine Chemicals of Guizhou University, Guiyang 550025, China.
Liu H; National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for R&D of Fine Chemicals of Guizhou University, Guiyang 550025, China.
Shao L; National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for R&D of Fine Chemicals of Guizhou University, Guiyang 550025, China.
Zhou X; National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for R&D of Fine Chemicals of Guizhou University, Guiyang 550025, China.
Liu L; National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for R&D of Fine Chemicals of Guizhou University, Guiyang 550025, China.
Yang S; National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for R&D of Fine Chemicals of Guizhou University, Guiyang 550025, China.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Jun 24; Vol. 24 (13). Date of Electronic Publication: 2023 Jun 24.
Typ publikacji:: Journal Article
MeSH Terms:: Triterpenes*/pharmacology
Triterpenes*/metabolism
Xanthomonas*/metabolism
Oryza*/metabolism
Reactive Oxygen Species/metabolism ; Amides/metabolism ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/metabolism ; Pentacyclic Triterpenes/pharmacology ; Pentacyclic Triterpenes/metabolism ; Plant Diseases/microbiology ; Microbial Sensitivity Tests
SCR Organism:: Xanthomonas oryzae; Xanthomonas citri

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Skocz do pozycji: 9.

Tytuł:: Pentacyclic Triterpenoid Phytochemicals with Anticancer Activity: Updated Studies on Mechanisms and Targeted Delivery.
Autorzy:: Nistor M; Department of Biochemistry, University of Agricultural Sciences and Veterinary Medicine, 400372 Cluj-Napoca, Romania.; Department of Biotechnology, BIODIATECH-Research Centre for Applied Biotechnology in Diagnosis and Molecular Therapy, 400478 Cluj-Napoca, Romania.
Rugina D; Department of Biochemistry, University of Agricultural Sciences and Veterinary Medicine, 400372 Cluj-Napoca, Romania.; Department of Biotechnology, BIODIATECH-Research Centre for Applied Biotechnology in Diagnosis and Molecular Therapy, 400478 Cluj-Napoca, Romania.
Diaconeasa Z; Department of Biochemistry, University of Agricultural Sciences and Veterinary Medicine, 400372 Cluj-Napoca, Romania.; Department of Biotechnology, BIODIATECH-Research Centre for Applied Biotechnology in Diagnosis and Molecular Therapy, 400478 Cluj-Napoca, Romania.
Socaciu C; Department of Biochemistry, University of Agricultural Sciences and Veterinary Medicine, 400372 Cluj-Napoca, Romania.; Department of Biotechnology, BIODIATECH-Research Centre for Applied Biotechnology in Diagnosis and Molecular Therapy, 400478 Cluj-Napoca, Romania.
Socaciu MA; Department of Biotechnology, BIODIATECH-Research Centre for Applied Biotechnology in Diagnosis and Molecular Therapy, 400478 Cluj-Napoca, Romania.; Department of Radiology, Imaging & Nuclear Medicine, Faculty of Medicine, University of Medicine and Pharmacy 'Iuliu Hatieganu', 400347 Cluj-Napoca, Romania.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Aug 18; Vol. 24 (16). Date of Electronic Publication: 2023 Aug 18.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Triterpenes*/pharmacology
Triterpenes*/therapeutic use
Phytochemicals/pharmacology ; Phytochemicals/therapeutic use ; Pentacyclic Triterpenes ; Contrast Media ; Erythrocytes, Abnormal ; Liposomes

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Skocz do pozycji: 10.

Tytuł:: Characterization of a Malabaricane-Type Triterpene Synthase from Astragalus membranaceus and Enzymatic Synthesis of Astramalabaricosides.
Autorzy:: Song Z; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, CAMS Key Laboratory of Enzyme and Biocatalysis of Natural Drugs, and NHC Key Laboratory of Biosynthesis of Natural Products, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
Chen D; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, CAMS Key Laboratory of Enzyme and Biocatalysis of Natural Drugs, and NHC Key Laboratory of Biosynthesis of Natural Products, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
Sui S; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, CAMS Key Laboratory of Enzyme and Biocatalysis of Natural Drugs, and NHC Key Laboratory of Biosynthesis of Natural Products, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
Wang Y; Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
Cen S; Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
Dai J; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, CAMS Key Laboratory of Enzyme and Biocatalysis of Natural Drugs, and NHC Key Laboratory of Biosynthesis of Natural Products, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.; Pokaż więcej
Źródło:: Journal of natural products [J Nat Prod] 2023 Jul 28; Vol. 86 (7), pp. 1815-1823. Date of Electronic Publication: 2023 Jun 19.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Astragalus propinquus*
Triterpenes*/pharmacology
Triterpenes*/chemistry
Molecular Docking Simulation ; Pentacyclic Triterpenes

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Szczegóły

Skocz do pozycji: 11.

Tytuł:: Gypsogenin Battling for a Front Position in the Pentacyclic Triterpenes Game of Thrones on Anti-Cancer Therapy: A Critical Review-Dedicated to the Memory of Professor Hanaa M. Rady.
Autorzy:: Radwan MO; Medicinal and Biological Chemistry Science Farm Joint Research Laboratory, Faculty of Life Sciences, Kumamoto University, Kumamoto 862-0973, Japan.; Chemistry of Natural Compounds Department, National Research Centre, Giza 12622, Egypt.
Abd-Alla HI; Chemistry of Natural Compounds Department, National Research Centre, Giza 12622, Egypt.
Alsaggaf AT; Department of Chemistry, Taibah University, Madinah 42353, Saudi Arabia.
El-Mezayen H; Biochemistry Department, Helwan University, Cairo 11795, Egypt.
Abourehab MAS; Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Minia University, Minia 61519, Egypt.; Department of Pharmaceutics, Faculty of Pharmacy, Umm Al-Qura University, Makkah 21955, Saudi Arabia.
El-Beeh ME; Biology Department, Al-Jumum University College, Umm Al-Qura University, Makkah 21955, Saudi Arabia.
Tateishi H; Medicinal and Biological Chemistry Science Farm Joint Research Laboratory, Faculty of Life Sciences, Kumamoto University, Kumamoto 862-0973, Japan.
Otsuka M; Medicinal and Biological Chemistry Science Farm Joint Research Laboratory, Faculty of Life Sciences, Kumamoto University, Kumamoto 862-0973, Japan.; Department of Drug Discovery, Science Farm Ltd., Kumamoto 862-0976, Japan.
Fujita M; Medicinal and Biological Chemistry Science Farm Joint Research Laboratory, Faculty of Life Sciences, Kumamoto University, Kumamoto 862-0973, Japan.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2023 Jul 27; Vol. 28 (15). Date of Electronic Publication: 2023 Jul 27.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Triterpenes*/chemistry
Oleanolic Acid*
Saponins*/therapeutic use
Neoplasms*/drug therapy
Humans ; Prospective Studies ; Pentacyclic Triterpenes/chemistry

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Skocz do pozycji: 12.

Tytuł:: Celastrol as an emerging anticancer agent: Current status, challenges and therapeutic strategies.
Autorzy:: Wang C; State Key Laboratory of Southwestern Chinese Medicine Resources, Key Laboratory of Standardization for Chinese Herbal Medicine, Ministry of Education, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.
Dai S; State Key Laboratory of Southwestern Chinese Medicine Resources, Key Laboratory of Standardization for Chinese Herbal Medicine, Ministry of Education, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.
Zhao X; State Key Laboratory of Southwestern Chinese Medicine Resources, Key Laboratory of Standardization for Chinese Herbal Medicine, Ministry of Education, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.
Zhang Y; State Key Laboratory of Southwestern Chinese Medicine Resources, Key Laboratory of Standardization for Chinese Herbal Medicine, Ministry of Education, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.
Gong L; State Key Laboratory of Southwestern Chinese Medicine Resources, Key Laboratory of Standardization for Chinese Herbal Medicine, Ministry of Education, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.
Fu K; State Key Laboratory of Southwestern Chinese Medicine Resources, Key Laboratory of Standardization for Chinese Herbal Medicine, Ministry of Education, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.
Ma C; State Key Laboratory of Southwestern Chinese Medicine Resources, Key Laboratory of Standardization for Chinese Herbal Medicine, Ministry of Education, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.
Peng C; State Key Laboratory of Southwestern Chinese Medicine Resources, Key Laboratory of Standardization for Chinese Herbal Medicine, Ministry of Education, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China. Electronic address: .
Li Y; State Key Laboratory of Southwestern Chinese Medicine Resources, Key Laboratory of Standardization for Chinese Herbal Medicine, Ministry of Education, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China. Electronic address: .; Pokaż więcej
Źródło:: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2023 Jul; Vol. 163, pp. 114882. Date of Electronic Publication: 2023 May 15.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/therapeutic use
Triterpenes*/pharmacology
Triterpenes*/therapeutic use
Prostatic Neoplasms*/drug therapy
Male ; Humans ; Signal Transduction ; Proto-Oncogene Proteins c-myc ; Phosphatidylinositol 3-Kinases ; Pentacyclic Triterpenes/pharmacology ; Apoptosis ; Cell Line, Tumor

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Skocz do pozycji: 13.

Tytuł:: Natural products of pentacyclic triterpenoids: from discovery to heterologous biosynthesis.
Autorzy:: Li Y; Ministry of Education, Key Laboratory of Saline-alkali Vegetation Ecology Restoration, Northeast Forestry University, Harbin, PR China. .; Heilongjiang Key Laboratory of Plant Bioactive Substance Biosynthesis and Utilization, Northeast Forestry University, Harbin, PR China.
Wang J; Institute of Forestry and Pomology, Beijing Academy of Agriculture and Forestry Sciences, Beijing, PR China.
Li L; Ministry of Education, Key Laboratory of Saline-alkali Vegetation Ecology Restoration, Northeast Forestry University, Harbin, PR China. .; Heilongjiang Key Laboratory of Plant Bioactive Substance Biosynthesis and Utilization, Northeast Forestry University, Harbin, PR China.
Song W; Ministry of Education, Key Laboratory of Saline-alkali Vegetation Ecology Restoration, Northeast Forestry University, Harbin, PR China. .; Heilongjiang Key Laboratory of Plant Bioactive Substance Biosynthesis and Utilization, Northeast Forestry University, Harbin, PR China.
Li M; Ministry of Education, Key Laboratory of Saline-alkali Vegetation Ecology Restoration, Northeast Forestry University, Harbin, PR China. .; Heilongjiang Key Laboratory of Plant Bioactive Substance Biosynthesis and Utilization, Northeast Forestry University, Harbin, PR China.
Hua X; Ministry of Education, Key Laboratory of Saline-alkali Vegetation Ecology Restoration, Northeast Forestry University, Harbin, PR China. .; Heilongjiang Key Laboratory of Plant Bioactive Substance Biosynthesis and Utilization, Northeast Forestry University, Harbin, PR China.
Wang Y; Ministry of Education, Key Laboratory of Saline-alkali Vegetation Ecology Restoration, Northeast Forestry University, Harbin, PR China. .
Yuan J; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, 361102, Fujian, PR China. .
Xue Z; Ministry of Education, Key Laboratory of Saline-alkali Vegetation Ecology Restoration, Northeast Forestry University, Harbin, PR China. .; Heilongjiang Key Laboratory of Plant Bioactive Substance Biosynthesis and Utilization, Northeast Forestry University, Harbin, PR China.; Pokaż więcej
Źródło:: Natural product reports [Nat Prod Rep] 2023 Aug 16; Vol. 40 (8), pp. 1303-1353. Date of Electronic Publication: 2023 Aug 16.
Typ publikacji:: Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:: Biological Products*/metabolism
Triterpenes*/chemistry
Saponins*/chemistry
Pentacyclic Triterpenes/metabolism ; Plants/metabolism

Czasopismo naukowe

na półce

Szczegóły

Skocz do pozycji: 14.

Tytuł:: A Novel Betulinic Acid Analogue: Synthesis, Solubility, Antitumor Activity and Pharmacokinetic Study in Rats.
Autorzy:: Liang Y; Key Laboratory of Saline-Alkali Vegetation Ecology Restoration in Oil Field, Ministry of Education, College of Life Sciences, Northeast Forestry University, Harbin 150040, China.
Zhu M; Key Laboratory of Saline-Alkali Vegetation Ecology Restoration in Oil Field, Ministry of Education, College of Life Sciences, Northeast Forestry University, Harbin 150040, China.; Changchun Institute of Biological Products Co., Ltd., Changchun 130011, China.
Xu T; Key Laboratory of Saline-Alkali Vegetation Ecology Restoration in Oil Field, Ministry of Education, College of Life Sciences, Northeast Forestry University, Harbin 150040, China.
Ding W; School of Chemical and Environmental Engineering, Harbin University of Science and Technology, Harbin 150040, China.
Chen M; Key Laboratory of Saline-Alkali Vegetation Ecology Restoration in Oil Field, Ministry of Education, College of Life Sciences, Northeast Forestry University, Harbin 150040, China.
Wang Y; Key Laboratory of Saline-Alkali Vegetation Ecology Restoration in Oil Field, Ministry of Education, College of Life Sciences, Northeast Forestry University, Harbin 150040, China.
Zheng J; Key Laboratory of Saline-Alkali Vegetation Ecology Restoration in Oil Field, Ministry of Education, College of Life Sciences, Northeast Forestry University, Harbin 150040, China.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2023 Jul 28; Vol. 28 (15). Date of Electronic Publication: 2023 Jul 28.
Typ publikacji:: Journal Article
MeSH Terms:: Betulinic Acid*
Triterpenes*/pharmacology
Humans ; Rats ; Animals ; HeLa Cells ; Solubility ; Pentacyclic Triterpenes ; Cell Line, Tumor

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 15.

Tytuł:: Four New Unusual Pentacyclic Triterpenoids from the Roots of Jasminum sambac (L.) Ait.
Autorzy:: Olatunde OZ; Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou 350002, China.; University of Chinese Academy of Sciences, Beijing 100049, China.
Yong J; Xiamen Institute of Rare-Earth Materials, Chinese Academy of Sciences, Xiamen 361021, China.
Lu C; Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou 350002, China.; Xiamen Institute of Rare-Earth Materials, Chinese Academy of Sciences, Xiamen 361021, China.; University of Chinese Academy of Sciences, Beijing 100049, China.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2023 Jun 29; Vol. 28 (13). Date of Electronic Publication: 2023 Jun 29.
Typ publikacji:: Journal Article
MeSH Terms:: Jasminum*/chemistry
Triterpenes*
Pentacyclic Triterpenes ; Magnetic Resonance Spectroscopy ; Molecular Structure

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 16.

Tytuł:: Sterols and pentacyclic triterpenoids from nettle root: content and composition as affected by pressurized liquid extraction.
Autorzy:: Cegledi E; Faculty of Food Technology and Biotechnology, University of Zagreb, Zagreb, Croatia.
Repajić M; Faculty of Food Technology and Biotechnology, University of Zagreb, Zagreb, Croatia.
Balbino S; Faculty of Food Technology and Biotechnology, University of Zagreb, Zagreb, Croatia.
Peričić M; Faculty of Food Technology and Biotechnology, University of Zagreb, Zagreb, Croatia.
Dragović-Uzelac V; Faculty of Food Technology and Biotechnology, University of Zagreb, Zagreb, Croatia.; Pokaż więcej
Źródło:: Journal of the science of food and agriculture [J Sci Food Agric] 2023 Jun; Vol. 103 (8), pp. 4058-4067. Date of Electronic Publication: 2022 Dec 14.
Typ publikacji:: Journal Article
MeSH Terms:: Phytosterols*
Triterpenes*
Urtica dioica*/chemistry
Sterols ; Pentacyclic Triterpenes ; Plant Extracts/chemistry

Czasopismo naukowe

na półce

Szczegóły

Skocz do pozycji: 17.

Tytuł:: A Classic Photochemical Approach Inducing an Unexpected Rearrangement: Exploring the Photoreactivity of Pentacyclic Triterpenic Acids.
Autorzy:: Rogati F; Dipartimento di Scienze del Farmaco, Università del Piemonte Orientale, Via Bovio 6, 28100 Novara, Italy.
Maioli C; Dipartimento di Scienze del Farmaco, Università del Piemonte Orientale, Via Bovio 6, 28100 Novara, Italy.
Lauro G; Dipartimento di Farmacia, Università degli Studi di Salerno, Via Giovanni Paolo II 132, 84084 Fisciano, Italy.
Caprioglio D; Dipartimento di Scienze del Farmaco, Università del Piemonte Orientale, Via Bovio 6, 28100 Novara, Italy.
Imperio D; Dipartimento di Scienze del Farmaco, Università del Piemonte Orientale, Via Bovio 6, 28100 Novara, Italy.
Del Grosso E; Dipartimento di Scienze del Farmaco, Università del Piemonte Orientale, Via Bovio 6, 28100 Novara, Italy.
Botta B; Dipartimento di Chimica e Tecnologie del Farmaco, Università la Sapienza, Piazzale Aldo Moro 5, 00185 Roma, Italy.
Mannina L; Dipartimento di Chimica e Tecnologie del Farmaco, Università la Sapienza, Piazzale Aldo Moro 5, 00185 Roma, Italy.
Bifulco G; Dipartimento di Farmacia, Università degli Studi di Salerno, Via Giovanni Paolo II 132, 84084 Fisciano, Italy.
Ingallina C; Dipartimento di Chimica e Tecnologie del Farmaco, Università la Sapienza, Piazzale Aldo Moro 5, 00185 Roma, Italy.
Minassi A; Dipartimento di Scienze del Farmaco, Università del Piemonte Orientale, Via Bovio 6, 28100 Novara, Italy.; PlantaChem srls, Via Canobio 4/6, 28100 Novara, Italy.; Pokaż więcej
Źródło:: Journal of natural products [J Nat Prod] 2023 Apr 28; Vol. 86 (4), pp. 1025-1032. Date of Electronic Publication: 2023 Apr 10.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Triterpenes*/pharmacology
Triterpenes*/analysis
Pentacyclic Triterpenes/pharmacology ; Chromatography, High Pressure Liquid

Czasopismo naukowe

na półce

Szczegóły

Skocz do pozycji: 18.

Tytuł:: Celastrol: A Potential Natural Lead Molecule for New Drug Design, Development and Therapy for Memory Impairment.
Autorzy:: Amir Yusri MA; Department of Pharmaceutical Chemistry, Faculty of Pharmacy and Health Sciences, Royal College of Medicine Perak, Universiti Kuala Lumpur, Ipoh, Perak, Malaysia.
Sekar M; School of Pharmacy, Monash University Malaysia, Bandar Sunway, Subang Jaya, Selangor, Malaysia.; Center for Transdisciplinary Research, Department of Pharmacology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Chennai, India.
Wong LS; Faculty of Health and Life Sciences, INTI International University, Nilai, Malaysia.
Gan SH; School of Pharmacy, Monash University Malaysia, Bandar Sunway, Subang Jaya, Selangor, Malaysia.
Ravi S; Department of Chemistry, Karpagam Academy of Higher Education, Coimbatore, Tamil Nadu, India.
Subramaniyan V; Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Bandar Sunway, Subang Jaya, Selangor, Malaysia.
Mat Rani NNI; Faculty of Pharmacy and Health Sciences, Royal College of Medicine Perak, Universiti Kuala Lumpur, Ipoh, Perak, Malaysia.
Chidambaram K; Department of Pharmacology, College of Pharmacy, King Khalid University, Abha, Saudi Arabia.
Begum MY; Department of Pharmaceutics, College of Pharmacy, King Khalid University, Abha, Saudi Arabia.
Ramar M; Department of Surgical Research, Rhode Island Hospital, Alpert Medical School, Brown University, Providence, RI, USA.
Safi SZ; Faculty of Medicine, Bioscience and Nursing, MAHSA University, Bandar Saujana Putra, Jenjarom, Selangor, Malaysia.
Selvaraj S; Faculty of Dentistry, AIMST University, Bedong, Kedah, Malaysia.
Wu YS; Department of Biological Sciences and Centre for Virus and Vaccine Research, School of Medical and Life Sciences, Sunway University, Subang Jaya, Selangor, Malaysia.
Revathy P; Department of Computer Applications, Gobi Arts & Science College, Gobichettipalayam, Tamil Nadu, India.
Fuloria S; Faculty of Pharmacy, AIMST University, Bedong, Kedah, Malaysia.
Fuloria NK; Faculty of Pharmacy, AIMST University, Bedong, Kedah, Malaysia.
Lum PT; Department of Pharmaceutical Chemistry, Faculty of Pharmacy and Health Sciences, Royal College of Medicine Perak, Universiti Kuala Lumpur, Ipoh, Perak, Malaysia.
Djearamane S; Department of Biomedical Science, Faculty of Science, Universiti Tunku Abdul Rahman, Kampar, Perak, Malaysia.; Pokaż więcej
Źródło:: Drug design, development and therapy [Drug Des Devel Ther] 2023 Apr 08; Vol. 17, pp. 1079-1096. Date of Electronic Publication: 2023 Apr 08 (Print Publication: 2023).
Typ publikacji:: Journal Article; Review
MeSH Terms:: Triterpenes*/pharmacology
Triterpenes*/therapeutic use
Triterpenes*/chemistry
Animals ; Pentacyclic Triterpenes/pharmacology ; Oxidative Stress ; Drug Design

Czasopismo naukowe

na półce

Szczegóły

Skocz do pozycji: 19.

Tytuł:: Self-assembling nanoarchitectonics of size-controllable celastrol nanoparticles for efficient cancer chemotherapy with reduced systemic toxicity.
Autorzy:: Liu Y; Beijing National Laboratory for Molecular Sciences (BNLMS), CAS Key Lab of Colloid, Interface and Chemical Thermodynamics, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China; University of Chinese Academy of Sciences, Beijing 100049, China.
Li J; Beijing National Laboratory for Molecular Sciences (BNLMS), CAS Key Lab of Colloid, Interface and Chemical Thermodynamics, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China; University of Chinese Academy of Sciences, Beijing 100049, China. Electronic address: .; Pokaż więcej
Źródło:: Journal of colloid and interface science [J Colloid Interface Sci] 2023 Apr 15; Vol. 636, pp. 216-222. Date of Electronic Publication: 2022 Dec 31.
Typ publikacji:: Journal Article
MeSH Terms:: Triterpenes*/pharmacology
Neoplasms*/drug therapy
Nanoparticles*
Mice ; Animals ; Pentacyclic Triterpenes/pharmacology

Czasopismo naukowe

na półce

Szczegóły

Skocz do pozycji: 20.

Tytuł:: Betulin and Its Derivatives Reduce Inflammation and COX-2 Activity in Macrophages.
Autorzy:: Szlasa W; Faculty of Medicine, Wroclaw Medical University, Wroclaw, Poland. .
Ślusarczyk S; Department of Pharmaceutical Biology and Biotechnology, Faculty of Pharmacy, Wroclaw Medical University, Wroclaw, Poland.
Nawrot-Hadzik I; Department of Pharmaceutical Biology and Biotechnology, Faculty of Pharmacy, Wroclaw Medical University, Wroclaw, Poland.
Abel R; Department of Pharmaceutical Biology and Biotechnology, Faculty of Pharmacy, Wroclaw Medical University, Wroclaw, Poland.; Institute of Physiology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität Zu Berlin, and Berlin Institute of Health, Berlin, Germany, Philippstrasse 12, 10115, Berlin, Germany.
Zalesińska A; Faculty of Medicine, Wroclaw Medical University, Wroclaw, Poland.
Szewczyk A; Department of Molecular and Cellular Biology, Faculty of Pharmacy, Wroclaw Medical University, Wroclaw, Poland.
Sauer N; Faculty of Pharmacy, Wrocław Medical University, Wroclaw, Poland.
Preissner R; Science-IT and Institute of Physiology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität Zu Berlin, and Berlin Institute of Health, Philippstrasse 12, 10115, Berlin, Germany.
Saczko J; Department of Molecular and Cellular Biology, Faculty of Pharmacy, Wroclaw Medical University, Wroclaw, Poland.
Drąg M; Department of Chemical Biology and Bioimaging, Faculty of Chemistry, Wrocław University of Science and Technology, Wybrzeże Wyspiańskiego 27, 50-370, Wroclaw, Poland.
Poręba M; Department of Chemical Biology and Bioimaging, Faculty of Chemistry, Wrocław University of Science and Technology, Wybrzeże Wyspiańskiego 27, 50-370, Wroclaw, Poland.
Daczewska M; Department of Animal Developmental Biology, Institute of Experimental Biology, University of Wroclaw, Wroclaw, Poland.
Kulbacka J; Department of Molecular and Cellular Biology, Faculty of Pharmacy, Wroclaw Medical University, Wroclaw, Poland. .
Drąg-Zalesińska M; Division of Histology and Embryology, Faculty of Medicine, Wroclaw Medical University, Wroclaw, Poland.; Pokaż więcej
Źródło:: Inflammation [Inflammation] 2023 Apr; Vol. 46 (2), pp. 573-583. Date of Electronic Publication: 2022 Oct 25.
Typ publikacji:: Journal Article
MeSH Terms:: Interleukin-6*/pharmacology
Triterpenes*/pharmacology
Animals ; Mice ; Pentacyclic Triterpenes/pharmacology ; Cyclooxygenase 2 ; Molecular Docking Simulation ; Inflammation/drug therapy ; Macrophages ; Anti-Inflammatory Agents/pharmacology ; Dexamethasone/pharmacology

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