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Tytuł:
Neuroprotective properties of Betulin, Betulinic acid, and Ursolic acid as triterpenoids derivatives: a comprehensive review of mechanistic studies.
Autorzy:
Farzan M; Student Research Committee, Shahrekord University of Medical Sciences, Shahrekord, Iran.; PhytoPharmacology Interest Group (PPIG), Universal Scientific Education and Research Network (USERN), Tehran, Iran.
Farzan M; Student Research Committee, Shahrekord University of Medical Sciences, Shahrekord, Iran.; Neuroscience Research Group (NRG), Universal Scientific Education and Research Network (USERN), Tehran, Iran.
Shahrani M; Medical Plants Research Center, Basic Health Sciences Institute, Shahrekord University of Medical Sciences, Shahrekord, Iran.
Navabi SP; Persian Gulf Physiology Research Center, Medical Basic Sciences Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Vardanjani HR; Department of Pharmacology, School of Pharmacy, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Amini-Khoei H; Medical Plants Research Center, Basic Health Sciences Institute, Shahrekord University of Medical Sciences, Shahrekord, Iran.
Shabani S; Medical Plants Research Center, Basic Health Sciences Institute, Shahrekord University of Medical Sciences, Shahrekord, Iran.
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Źródło:
Nutritional neuroscience [Nutr Neurosci] 2024 Mar; Vol. 27 (3), pp. 223-240. Date of Electronic Publication: 2023 Feb 23.
Typ publikacji:
Review; Journal Article
MeSH Terms:
Triterpenes*/therapeutic use
Triterpenes*/pharmacology
Neurodegenerative Diseases*/drug therapy
Humans ; Ursolic Acid ; Pentacyclic Triterpenes ; Betulinic Acid
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Betulinic Acid for Glioblastoma Treatment: Reality, Challenges and Perspectives.
Autorzy:
Fernandes S; Center for Translational Health and Medical Biotechnology Research (TBIO), School of Health (ESS), Polytechnic University of Porto, Rua Dr. António Bernardino de Almeida, 400, 4200-072 Porto, Portugal.; Center for Research on Health and Environment (CISA), School of Health (ESS), Polytechnic University of Porto, Rua Dr. António Bernardino de Almeida, 400, 4200-072 Porto, Portugal.
Vieira M; Center for Translational Health and Medical Biotechnology Research (TBIO), School of Health (ESS), Polytechnic University of Porto, Rua Dr. António Bernardino de Almeida, 400, 4200-072 Porto, Portugal.
Prudêncio C; Center for Translational Health and Medical Biotechnology Research (TBIO), School of Health (ESS), Polytechnic University of Porto, Rua Dr. António Bernardino de Almeida, 400, 4200-072 Porto, Portugal.; Ciências Químicas e das Biomoléculas, School of Health (ESS), Polytechnic University of Porto, Rua Dr. António Bernardino de Almeida, 400, 4200-072 Porto, Portugal.
Ferraz R; Center for Translational Health and Medical Biotechnology Research (TBIO), School of Health (ESS), Polytechnic University of Porto, Rua Dr. António Bernardino de Almeida, 400, 4200-072 Porto, Portugal.; Ciências Químicas e das Biomoléculas, School of Health (ESS), Polytechnic University of Porto, Rua Dr. António Bernardino de Almeida, 400, 4200-072 Porto, Portugal.; LAQV-REQUIMTE, Departamento de Química e Bioquímica, Faculdade de Ciências, Universidade do Porto, Rua do Campo Alegre, 687, 4169-007 Porto, Portugal.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 09; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 09.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Glioblastoma*/drug therapy
Glioblastoma*/pathology
Triterpenes*/pharmacology
Triterpenes*/therapeutic use
Triterpenes*/chemistry
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/therapeutic use
Antineoplastic Agents*/chemistry
Humans ; Pentacyclic Triterpenes/therapeutic use ; Betulinic Acid
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The Nexus of Inflammation-Induced Epithelial-Mesenchymal Transition and Lung Cancer Progression: A Roadmap to Pentacyclic Triterpenoid-Based Therapies.
Autorzy:
Odarenko KV; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, 630090 Novosibirsk, Russia.; Faculty of Natural Sciences, Novosibirsk State University, 630090 Novosibirsk, Russia.
Zenkova MA; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, 630090 Novosibirsk, Russia.
Markov AV; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, 630090 Novosibirsk, Russia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Dec 10; Vol. 24 (24). Date of Electronic Publication: 2023 Dec 10.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Lung Neoplasms*/drug therapy
Lung Neoplasms*/pathology
Triterpenes*/pharmacology
Triterpenes*/therapeutic use
Humans ; Signal Transduction ; Neoplasm Recurrence, Local/pathology ; Epithelial-Mesenchymal Transition ; Inflammation/drug therapy ; Inflammation/pathology ; Pentacyclic Triterpenes/therapeutic use ; Neoplastic Stem Cells/pathology ; Tumor Microenvironment
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Selected Plant Triterpenoids and Their Derivatives as Antiviral Agents.
Autorzy:
Wimmerová M; Department of Chemistry of Natural Compounds, University of Chemistry and Technology in Prague, Technická 5, 16028 Prague, Czech Republic.; Isotope Laboratory, Institute of Experimental Botany, Academy of Sciences of the Czech Republic, Vídeňská 1083, 14220 Prague, Czech Republic.
Bildziukevich U; Isotope Laboratory, Institute of Experimental Botany, Academy of Sciences of the Czech Republic, Vídeňská 1083, 14220 Prague, Czech Republic.
Wimmer Z; Department of Chemistry of Natural Compounds, University of Chemistry and Technology in Prague, Technická 5, 16028 Prague, Czech Republic.; Isotope Laboratory, Institute of Experimental Botany, Academy of Sciences of the Czech Republic, Vídeňská 1083, 14220 Prague, Czech Republic.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Nov 22; Vol. 28 (23). Date of Electronic Publication: 2023 Nov 22.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Triterpenes*/pharmacology
Triterpenes*/chemistry
Antiviral Agents/pharmacology ; Betulinic Acid ; Pentacyclic Triterpenes/pharmacology ; Plants
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Pentacyclic Triterpenoid Phytochemicals with Anticancer Activity: Updated Studies on Mechanisms and Targeted Delivery.
Autorzy:
Nistor M; Department of Biochemistry, University of Agricultural Sciences and Veterinary Medicine, 400372 Cluj-Napoca, Romania.; Department of Biotechnology, BIODIATECH-Research Centre for Applied Biotechnology in Diagnosis and Molecular Therapy, 400478 Cluj-Napoca, Romania.
Rugina D; Department of Biochemistry, University of Agricultural Sciences and Veterinary Medicine, 400372 Cluj-Napoca, Romania.; Department of Biotechnology, BIODIATECH-Research Centre for Applied Biotechnology in Diagnosis and Molecular Therapy, 400478 Cluj-Napoca, Romania.
Diaconeasa Z; Department of Biochemistry, University of Agricultural Sciences and Veterinary Medicine, 400372 Cluj-Napoca, Romania.; Department of Biotechnology, BIODIATECH-Research Centre for Applied Biotechnology in Diagnosis and Molecular Therapy, 400478 Cluj-Napoca, Romania.
Socaciu C; Department of Biochemistry, University of Agricultural Sciences and Veterinary Medicine, 400372 Cluj-Napoca, Romania.; Department of Biotechnology, BIODIATECH-Research Centre for Applied Biotechnology in Diagnosis and Molecular Therapy, 400478 Cluj-Napoca, Romania.
Socaciu MA; Department of Biotechnology, BIODIATECH-Research Centre for Applied Biotechnology in Diagnosis and Molecular Therapy, 400478 Cluj-Napoca, Romania.; Department of Radiology, Imaging & Nuclear Medicine, Faculty of Medicine, University of Medicine and Pharmacy 'Iuliu Hatieganu', 400347 Cluj-Napoca, Romania.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Aug 18; Vol. 24 (16). Date of Electronic Publication: 2023 Aug 18.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Triterpenes*/pharmacology
Triterpenes*/therapeutic use
Phytochemicals/pharmacology ; Phytochemicals/therapeutic use ; Pentacyclic Triterpenes ; Contrast Media ; Erythrocytes, Abnormal ; Liposomes
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Pentacyclic Triterpenes from Olive Leaves Formulated in Microemulsion: Characterization and Role in De Novo Lipogenesis in HepG2 Cells.
Autorzy:
Vasarri M; Department of Experimental and Clinical Biomedical Sciences, University of Florence, Viale Morgagni 50, 50134 Florence, Italy.; Department of Chemistry, University of Florence, Via U. Schiff 6, 50519 Sesto Fiorentino, Italy.
Degl'Innocenti D; Department of Experimental and Clinical Biomedical Sciences, University of Florence, Viale Morgagni 50, 50134 Florence, Italy.
Albonetti L; Department of Chemistry, University of Florence, Via U. Schiff 6, 50519 Sesto Fiorentino, Italy.
Bilia AR; Department of Chemistry, University of Florence, Via U. Schiff 6, 50519 Sesto Fiorentino, Italy.
Bergonzi MC; Department of Chemistry, University of Florence, Via U. Schiff 6, 50519 Sesto Fiorentino, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jul 28; Vol. 24 (15). Date of Electronic Publication: 2023 Jul 28.
Typ publikacji:
Journal Article
MeSH Terms:
Olea*
Carcinoma, Hepatocellular*/drug therapy
Liver Neoplasms*/drug therapy
Triterpenes*/pharmacology
Triterpenes*/chemistry
Humans ; Pentacyclic Triterpenes ; Lipogenesis ; Hep G2 Cells ; Emulsions/chemistry ; Membranes, Artificial ; Plant Leaves ; Lipids
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Discovery of Novel Pentacyclic Triterpene Acid Amide Derivatives as Excellent Antimicrobial Agents Dependent on Generation of Reactive Oxygen Species.
Autorzy:
Yang Y; National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for R&D of Fine Chemicals of Guizhou University, Guiyang 550025, China.
Chen K; National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for R&D of Fine Chemicals of Guizhou University, Guiyang 550025, China.
Wang G; National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for R&D of Fine Chemicals of Guizhou University, Guiyang 550025, China.
Liu H; National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for R&D of Fine Chemicals of Guizhou University, Guiyang 550025, China.
Shao L; National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for R&D of Fine Chemicals of Guizhou University, Guiyang 550025, China.
Zhou X; National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for R&D of Fine Chemicals of Guizhou University, Guiyang 550025, China.
Liu L; National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for R&D of Fine Chemicals of Guizhou University, Guiyang 550025, China.
Yang S; National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for R&D of Fine Chemicals of Guizhou University, Guiyang 550025, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jun 24; Vol. 24 (13). Date of Electronic Publication: 2023 Jun 24.
Typ publikacji:
Journal Article
MeSH Terms:
Triterpenes*/pharmacology
Triterpenes*/metabolism
Xanthomonas*/metabolism
Oryza*/metabolism
Reactive Oxygen Species/metabolism ; Amides/metabolism ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/metabolism ; Pentacyclic Triterpenes/pharmacology ; Pentacyclic Triterpenes/metabolism ; Plant Diseases/microbiology ; Microbial Sensitivity Tests
SCR Organism:
Xanthomonas oryzae; Xanthomonas citri
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Gypsogenin Battling for a Front Position in the Pentacyclic Triterpenes Game of Thrones on Anti-Cancer Therapy: A Critical Review-Dedicated to the Memory of Professor Hanaa M. Rady.
Autorzy:
Radwan MO; Medicinal and Biological Chemistry Science Farm Joint Research Laboratory, Faculty of Life Sciences, Kumamoto University, Kumamoto 862-0973, Japan.; Chemistry of Natural Compounds Department, National Research Centre, Giza 12622, Egypt.
Abd-Alla HI; Chemistry of Natural Compounds Department, National Research Centre, Giza 12622, Egypt.
Alsaggaf AT; Department of Chemistry, Taibah University, Madinah 42353, Saudi Arabia.
El-Mezayen H; Biochemistry Department, Helwan University, Cairo 11795, Egypt.
Abourehab MAS; Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Minia University, Minia 61519, Egypt.; Department of Pharmaceutics, Faculty of Pharmacy, Umm Al-Qura University, Makkah 21955, Saudi Arabia.
El-Beeh ME; Biology Department, Al-Jumum University College, Umm Al-Qura University, Makkah 21955, Saudi Arabia.
Tateishi H; Medicinal and Biological Chemistry Science Farm Joint Research Laboratory, Faculty of Life Sciences, Kumamoto University, Kumamoto 862-0973, Japan.
Otsuka M; Medicinal and Biological Chemistry Science Farm Joint Research Laboratory, Faculty of Life Sciences, Kumamoto University, Kumamoto 862-0973, Japan.; Department of Drug Discovery, Science Farm Ltd., Kumamoto 862-0976, Japan.
Fujita M; Medicinal and Biological Chemistry Science Farm Joint Research Laboratory, Faculty of Life Sciences, Kumamoto University, Kumamoto 862-0973, Japan.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Jul 27; Vol. 28 (15). Date of Electronic Publication: 2023 Jul 27.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Triterpenes*/chemistry
Oleanolic Acid*
Saponins*/therapeutic use
Neoplasms*/drug therapy
Humans ; Prospective Studies ; Pentacyclic Triterpenes/chemistry
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A Novel Betulinic Acid Analogue: Synthesis, Solubility, Antitumor Activity and Pharmacokinetic Study in Rats.
Autorzy:
Liang Y; Key Laboratory of Saline-Alkali Vegetation Ecology Restoration in Oil Field, Ministry of Education, College of Life Sciences, Northeast Forestry University, Harbin 150040, China.
Zhu M; Key Laboratory of Saline-Alkali Vegetation Ecology Restoration in Oil Field, Ministry of Education, College of Life Sciences, Northeast Forestry University, Harbin 150040, China.; Changchun Institute of Biological Products Co., Ltd., Changchun 130011, China.
Xu T; Key Laboratory of Saline-Alkali Vegetation Ecology Restoration in Oil Field, Ministry of Education, College of Life Sciences, Northeast Forestry University, Harbin 150040, China.
Ding W; School of Chemical and Environmental Engineering, Harbin University of Science and Technology, Harbin 150040, China.
Chen M; Key Laboratory of Saline-Alkali Vegetation Ecology Restoration in Oil Field, Ministry of Education, College of Life Sciences, Northeast Forestry University, Harbin 150040, China.
Wang Y; Key Laboratory of Saline-Alkali Vegetation Ecology Restoration in Oil Field, Ministry of Education, College of Life Sciences, Northeast Forestry University, Harbin 150040, China.
Zheng J; Key Laboratory of Saline-Alkali Vegetation Ecology Restoration in Oil Field, Ministry of Education, College of Life Sciences, Northeast Forestry University, Harbin 150040, China.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Jul 28; Vol. 28 (15). Date of Electronic Publication: 2023 Jul 28.
Typ publikacji:
Journal Article
MeSH Terms:
Betulinic Acid*
Triterpenes*/pharmacology
Humans ; Rats ; Animals ; HeLa Cells ; Solubility ; Pentacyclic Triterpenes ; Cell Line, Tumor
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Four New Unusual Pentacyclic Triterpenoids from the Roots of Jasminum sambac (L.) Ait.
Autorzy:
Olatunde OZ; Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou 350002, China.; University of Chinese Academy of Sciences, Beijing 100049, China.
Yong J; Xiamen Institute of Rare-Earth Materials, Chinese Academy of Sciences, Xiamen 361021, China.
Lu C; Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou 350002, China.; Xiamen Institute of Rare-Earth Materials, Chinese Academy of Sciences, Xiamen 361021, China.; University of Chinese Academy of Sciences, Beijing 100049, China.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Jun 29; Vol. 28 (13). Date of Electronic Publication: 2023 Jun 29.
Typ publikacji:
Journal Article
MeSH Terms:
Jasminum*/chemistry
Triterpenes*
Pentacyclic Triterpenes ; Magnetic Resonance Spectroscopy ; Molecular Structure
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Antiandrogen enzalutamide induced genetic, cellular, and hepatic damages: amelioration by triterpene Lupeol.
Autorzy:
Khan MA; Department of Zoology, Aligarh Muslim University, Aligarh, India.
Singh D; Department of Zoology, Aligarh Muslim University, Aligarh, India.
Fatma H; Department of Zoology, Aligarh Muslim University, Aligarh, India.
Akhtar K; Department of Pathology, JNMC, Aligarh, India.
Arjmand F; Department of Chemistry, Aligarh Muslim University, Aligarh, India.
Maurya S; Department of Zoology, Aligarh Muslim University, Aligarh, India.
Siddique HR; Department of Zoology, Aligarh Muslim University, Aligarh, India.
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Źródło:
Drug and chemical toxicology [Drug Chem Toxicol] 2023 Mar; Vol. 46 (2), pp. 380-391. Date of Electronic Publication: 2022 Feb 21.
Typ publikacji:
Journal Article
MeSH Terms:
Triterpenes*/pharmacology
Prostatic Neoplasms*/drug therapy
Male ; Humans ; Androgen Antagonists/pharmacology ; Pentacyclic Triterpenes ; Nitriles/pharmacology ; Receptors, Androgen/genetics ; Cell Line, Tumor
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Betulinic acid may modulate autophagy in renal cell carcinoma cells.
Autorzy:
Atas MN
Ertugrul B
Iplik ES
Cakmakoglu B
Ergen A
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Źródło:
Bratislavske lekarske listy [Bratisl Lek Listy] 2023; Vol. 124 (2), pp. 104-108.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Renal Cell*/drug therapy
Triterpenes*/pharmacology
Kidney Neoplasms*/drug therapy
Humans ; Pentacyclic Triterpenes ; Betulinic Acid ; Beclin-1/genetics ; Autophagy
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Astragaloside IV-PESV inhibits prostate cancer tumor growth by restoring gut microbiota and microbial metabolic homeostasis via the AGE-RAGE pathway.
Autorzy:
You X; Department of Andrology, Shenzhen Bao'an Traditional Chinese Medicine Hospital, Guangzhou University of Chinese Medicine, 518101, Shenzhen, China.
Qiu J; Department of Andrology, Shenzhen Traditional Chinese Medicine Hospital, Guangzhou University of Chinese Medicine, 518033, Shenzhen, China.
Li Q; Department of Andrology, Shenzhen Bao'an Traditional Chinese Medicine Hospital, Guangzhou University of Chinese Medicine, 518101, Shenzhen, China.
Zhang Q; Department of Andrology, Shenzhen Bao'an Traditional Chinese Medicine Hospital, Guangzhou University of Chinese Medicine, 518101, Shenzhen, China.
Sheng W; School of Rehabilitation Medicine and Health Care, Hunan University of Medicine, 418000, Huaihua, China.; School of Traditional Chinese Medicine, Hunan University of Medicine, 418000, Huaihua, China.
Cao Y; Department of Urology Surgery, Shenzhen Bao'an Traditional Chinese Medicine Hospital, Guangzhou University of Chinese Medicine, 518101, Shenzhen, China. .
Fu W; Department of Andrology, Shenzhen Bao'an Traditional Chinese Medicine Hospital, Guangzhou University of Chinese Medicine, 518101, Shenzhen, China. .
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Źródło:
BMC cancer [BMC Cancer] 2024 Apr 15; Vol. 24 (1), pp. 472. Date of Electronic Publication: 2024 Apr 15.
Typ publikacji:
Journal Article
MeSH Terms:
Gastrointestinal Microbiome*
Liver Neoplasms*
Prostatic Neoplasms*/drug therapy
Saponins*
Triterpenes*
Male ; Humans ; Animals ; Mice ; Mice, Nude ; Receptor for Advanced Glycation End Products ; Homeostasis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Triterpenoids from the Leaves of Diospyros digyna and Their PTP1B Inhibitory Activity.
Autorzy:
Huang L; Guangdong Provincial Engineering Research Center for Modernization of TCM, Jinan University, Guangzhou 510632, China.; NMPA Key Laboratory for Quality Evaluation of TCM, Jinan University, Guangzhou 510632, China.
Wang Z; Guangdong Provincial Engineering Research Center for Modernization of TCM, Jinan University, Guangzhou 510632, China.; NMPA Key Laboratory for Quality Evaluation of TCM, Jinan University, Guangzhou 510632, China.; Guangdong Institute for Drug Control, Guangzhou 510663, China.
Wang F; Guangdong Provincial Engineering Research Center for Modernization of TCM, Jinan University, Guangzhou 510632, China.; NMPA Key Laboratory for Quality Evaluation of TCM, Jinan University, Guangzhou 510632, China.
Wang S; Guangdong Provincial Engineering Research Center for Modernization of TCM, Jinan University, Guangzhou 510632, China.; NMPA Key Laboratory for Quality Evaluation of TCM, Jinan University, Guangzhou 510632, China.
Wang D; Guangdong Provincial Engineering Research Center for Modernization of TCM, Jinan University, Guangzhou 510632, China.; NMPA Key Laboratory for Quality Evaluation of TCM, Jinan University, Guangzhou 510632, China.
Gao M; Guangdong Institute for Drug Control, Guangzhou 510663, China.
Li H; Guangdong Institute for Drug Control, Guangzhou 510663, China.
Song M; Guangdong Provincial Engineering Research Center for Modernization of TCM, Jinan University, Guangzhou 510632, China.; NMPA Key Laboratory for Quality Evaluation of TCM, Jinan University, Guangzhou 510632, China.
Zhang X; Guangdong Provincial Engineering Research Center for Modernization of TCM, Jinan University, Guangzhou 510632, China.; NMPA Key Laboratory for Quality Evaluation of TCM, Jinan University, Guangzhou 510632, China.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2024 Apr 05; Vol. 29 (7). Date of Electronic Publication: 2024 Apr 05.
Typ publikacji:
Journal Article
MeSH Terms:
Diospyros*
Triterpenes*/pharmacology
Molecular Docking Simulation ; Plant Leaves ; Hydroxy Acids
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Astragaloside IV as a Memory-Enhancing Agent: In Silico Studies with In Vivo Analysis and Post Mortem ADME-Tox Profiling in Mice.
Autorzy:
Stępnik K; Department of Physical Chemistry, Institute of Chemical Sciences, Faculty of Chemistry, Maria Curie-Skłodowska University in Lublin, Pl. M. Curie-Skłodowskiej 3, 20-031 Lublin, Poland.; Department of Pharmacognosy with Medicinal Plants Garden, Medical University of Lublin, 1 Chodzki St., 20-093 Lublin, Poland.
Kukula-Koch W; Department of Pharmacognosy with Medicinal Plants Garden, Medical University of Lublin, 1 Chodzki St., 20-093 Lublin, Poland.
Boguszewska-Czubara A; Department of Medical Chemistry, Medical University of Lublin, 4A Chodźki St., 20-093 Lublin, Poland.
Gawel K; Department of Experimental and Clinical Pharmacology, Medical University of Lublin, 8B Jaczewskiego St., 20-090 Lublin, Poland.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Apr 04; Vol. 25 (7). Date of Electronic Publication: 2024 Apr 04.
Typ publikacji:
Journal Article
MeSH Terms:
Saponins*/pharmacology
Triterpenes*/pharmacology
Humans ; Animals ; Mice ; Acetylcholinesterase ; Memory Disorders/drug therapy ; Lipopolysaccharides/toxicity
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
In Silico Approach Triterpene Glycoside of H. atra Targeting Orotidine 5-Monophosphate Decarboxylase Protein (PfOMPDC) in P. falciparum Infection Mechanism.
Autorzy:
Utami PD; Parasitology Departement, Faculty of Medicine, Hang Tuah University, Surabaya, Indonesia.
Setianingsih H; Anatomy and Histology Departement, Faculty of Medicine, Hang Tuah University, Surabaya, Indonesia.
Sari DRT; Pharmacy Department, Faculty of Medical Science, Ibrahimy University, Situbondo, Indonesia.
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Źródło:
BioMed research international [Biomed Res Int] 2024 Apr 01; Vol. 2024, pp. 5924799. Date of Electronic Publication: 2024 Apr 01 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Triterpenes*/chemistry
Carboxy-Lyases*
Cardiac Glycosides*
Uridine/*analogs & derivatives
Molecular Docking Simulation ; Glycosides/chemistry
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
HMGR and CHS gene cloning, characterizations and tissue-specific expressions in Polygala tenuifolia Willd.
Autorzy:
Liu Y; College of Pharmacy, Hebei University of Chinese Medicine, Shijiazhuang, Hebei Province, China.; Traditional Chinese Medicine Processing Technology Innovation Center of Hebei Province, Shijiazhuang, Hebei Province, China.; International Joint Research Center on Resource Utilization and Quality Evaluation of Traditional Chinese Medicine of Hebei Province, Shijiazhuang, Hebei Province, China.
Ma X; Yinchuan Women and Children Health Care Hospital, Yinchuan, Ningxia, China.
Mao F; Experimental Center, Hebei University of Chinese Medicine, Shijiazhuang, Hebei Province, China.
Qiu J; College of Pharmacy, Hebei University of Chinese Medicine, Shijiazhuang, Hebei Province, China.
Bi J; College of Pharmacy, Hebei University of Chinese Medicine, Shijiazhuang, Hebei Province, China.
Li X; College of Pharmacy, Hebei University of Chinese Medicine, Shijiazhuang, Hebei Province, China.
Gu X; College of Pharmacy, Hebei University of Chinese Medicine, Shijiazhuang, Hebei Province, China.
Zheng Y; Traditional Chinese Medicine Processing Technology Innovation Center of Hebei Province, Shijiazhuang, Hebei Province, China.; Hebei Chemical and Pharmaceutical College, Shijiazhuang, Hebei Province, China.
Zhao Y; College of Pharmacy, Hebei University of Chinese Medicine, Shijiazhuang, Hebei Province, China.; Traditional Chinese Medicine Processing Technology Innovation Center of Hebei Province, Shijiazhuang, Hebei Province, China.; International Joint Research Center on Resource Utilization and Quality Evaluation of Traditional Chinese Medicine of Hebei Province, Shijiazhuang, Hebei Province, China.
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Źródło:
PloS one [PLoS One] 2024 Mar 25; Vol. 19 (3), pp. e0300895. Date of Electronic Publication: 2024 Mar 25 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Polygala*/metabolism
Saponins*/genetics
Triterpenes*/metabolism
Acyltransferases*
Oxidoreductases ; Cloning, Molecular ; Amino Acids ; Flavonoids ; Phylogeny
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
LC/MS/MS and GC/MS/MS metabolic profiling of Leontodon hispidulus, in vitro and in silico anticancer activity evaluation targeting hexokinase 2 enzyme.
Autorzy:
Abd-El-Aziz NM; Department of Medicinal and Aromatic Plants, Desert Research Center, Cairo, Egypt. .
Hifnawy MS; Department of Pharmacognosy, Faculty of Pharmacy, Cairo University, El Kaser El-Aini, Cairo, 11562, Egypt.
Lotfy RA; Department of Medicinal and Aromatic Plants, Desert Research Center, Cairo, Egypt.
Younis IY; Department of Pharmacognosy, Faculty of Pharmacy, Cairo University, El Kaser El-Aini, Cairo, 11562, Egypt.
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Źródło:
Scientific reports [Sci Rep] 2024 Mar 22; Vol. 14 (1), pp. 6872. Date of Electronic Publication: 2024 Mar 22.
Typ publikacji:
Journal Article
MeSH Terms:
Tandem Mass Spectrometry*
Asteraceae*
Pentacyclic Triterpenes*
Apigenin ; Quercetin ; Hexokinase ; Esculin ; Plant Extracts/pharmacology ; Plant Extracts/chemistry ; Glucosides/chemistry ; Antioxidants/chemistry
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Asiatic acid cyclodextrin inclusion micro-cocrystal for insoluble drug delivery and acute lung injury therapy enhancement.
Autorzy:
Shen H; Zhongshan Institute for Drug Discovery, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Zhongshan, 528400, China.; State Key Laboratory of Drug Research, Chinese Academy of Sciences, Shanghai, 201203, China.
Pan L; School of Pharmacy, Zunyi Medical University, Zunyi, 563003, China.
Ning K; School of Pharmacy, Zunyi Medical University, Zunyi, 563003, China.
Fang Y; Zhongshan Institute for Drug Discovery, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Zhongshan, 528400, China.
Muhitdinov B; Institute of Bioorganic Chemistry, Uzbekistan Academy of Sciences, 83 M. Ulughbek Street, Tashkent, 100125, Uzbekistan.
Liu E; Zhongshan Institute for Drug Discovery, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Zhongshan, 528400, China. .
Huang Y; Zhongshan Institute for Drug Discovery, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Zhongshan, 528400, China. .; State Key Laboratory of Drug Research, Chinese Academy of Sciences, Shanghai, 201203, China. .; School of Pharmacy, Zunyi Medical University, Zunyi, 563003, China. .; NMPA Key Laboratory for Quality Research and Evaluation of Pharmaceutical Excipients, Shanghai, 201203, China. .
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Źródło:
Journal of nanobiotechnology [J Nanobiotechnology] 2024 Mar 17; Vol. 22 (1), pp. 119. Date of Electronic Publication: 2024 Mar 17.
Typ publikacji:
Journal Article
MeSH Terms:
Cyclodextrins*/chemistry
Acute Lung Injury*/drug therapy
Pentacyclic Triterpenes*
Humans ; Tissue Distribution ; Drug Delivery Systems ; Solubility
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Comprehensive Characterization of Triterpene Saponins in Rhizoma Panacis Japonici by Offline Two-Dimensional Liquid Chromatography Coupled to Quadrupole Time-of-Flight Mass Spectrometry.
Autorzy:
Yasen S; School of Traditional Chinese Medicine, Capital Medical University, Beijing 100069, China.
Li C; School of Traditional Chinese Medicine, Capital Medical University, Beijing 100069, China.
Wang S; School of Traditional Chinese Medicine, Capital Medical University, Beijing 100069, China.
Dong Y; School of Traditional Chinese Medicine, Capital Medical University, Beijing 100069, China.
Li H; School of Traditional Chinese Medicine, Capital Medical University, Beijing 100069, China.
Chen J; School of Traditional Chinese Medicine, Capital Medical University, Beijing 100069, China.
Meng Y; School of Traditional Chinese Medicine, Capital Medical University, Beijing 100069, China.
Yu P; School of Traditional Chinese Medicine, Capital Medical University, Beijing 100069, China.
Zou H; School of Traditional Chinese Medicine, Capital Medical University, Beijing 100069, China.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2024 Mar 14; Vol. 29 (6). Date of Electronic Publication: 2024 Mar 14.
Typ publikacji:
Journal Article
MeSH Terms:
Saponins*/chemistry
Triterpenes*/chemistry
Plants, Medicinal*/chemistry
Drugs, Chinese Herbal*
Panax*
Chromatography, High Pressure Liquid/methods ; Plant Extracts/chemistry ; Mass Spectrometry
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
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