Temat: "Trypanosoma brucei brucei" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Consistent detection of Trypanosoma brucei but not T. congolense DNA in faeces of experimentally infected cattle.
Autorzy:: Saldanha I; Vector Biology Department, Liverpool School of Tropical Medicine, Liverpool, UK. .
Betson M; School of Veterinary Medicine, University of Surrey, Guildford, UK.
Vrettou C; Roslin Institute, University of Edinburgh, Edinburgh, UK.
Paxton E; Roslin Institute, University of Edinburgh, Edinburgh, UK.
Nixon J; Large Animal Research and Imaging Facility, University of Edinburgh, Edinburgh, UK.
Tennant P; Large Animal Research and Imaging Facility, University of Edinburgh, Edinburgh, UK.
Ritchie A; Large Animal Research and Imaging Facility, University of Edinburgh, Edinburgh, UK.
Matthews KR; Institute of Immunology and Infection, University of Edinburgh, Edinburgh, UK.
Morrison LJ; Roslin Institute, University of Edinburgh, Edinburgh, UK.
Torr SJ; Vector Biology Department, Liverpool School of Tropical Medicine, Liverpool, UK.
Cunningham LJ; Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool, UK.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Feb 20; Vol. 14 (1), pp. 4158. Date of Electronic Publication: 2024 Feb 20.
Typ publikacji:: Journal Article
MeSH Terms:: Trypanosoma brucei brucei*/genetics
Trypanosoma congolense*/genetics
Trypanosomiasis, African*/diagnosis
Trypanosomiasis, African*/veterinary
Trypanosomiasis, African*/epidemiology
Trypanosoma*/genetics
Humans ; Cattle ; Animals ; DNA ; Feces

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Skocz do pozycji: 2.

Tytuł:: Adaptation of CUT&RUN for use in African trypanosomes.
Autorzy:: Miller G; Harvey Mudd College, Claremont, CA, United States of America.
Rollosson LM; Harvey Mudd College, Claremont, CA, United States of America.
Saada C; Harvey Mudd College, Claremont, CA, United States of America.
Wade SJ; Harvey Mudd College, Claremont, CA, United States of America.
Schulz D; Harvey Mudd College, Claremont, CA, United States of America.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2023 Nov 21; Vol. 18 (11), pp. e0292784. Date of Electronic Publication: 2023 Nov 21 (Print Publication: 2023).
Typ publikacji:: Journal Article
MeSH Terms:: Trypanosoma*/genetics
Trypanosoma brucei brucei*/metabolism
Trypanosomiasis, African*/parasitology
Animals

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Skocz do pozycji: 3.

Tytuł:: Performance of diagnostic tests for Trypanosoma brucei brucei in experimentally infected pigs.
Autorzy:: Ilboudo K; Unité de Recherche sur les Maladies à Vecteurs et Biodiversité, Centre International de Recherche-Développement sur l'Elevage en zone Subhumide, Bobo-Dioulasso, Burkina Faso.; Unité de Formation et de Recherche en Sciences de la Vie et de la Terre, Université Nazi Boni, Bobo-Dioulasso, Burkina Faso.
Boulangé A; Unité de Recherche sur les Maladies à Vecteurs et Biodiversité, Centre International de Recherche-Développement sur l'Elevage en zone Subhumide, Bobo-Dioulasso, Burkina Faso.; Unité de Recherche « Trypanosomoses », Institut Pierre Richet, Bouaké, Côte d'Ivoire.; CIRAD, UMR INTERTRYP, Montpellier, France.; INTERTRYP, University of Montpellier, CIRAD, IRD, Montpellier, France.
Hounyèmè RE; Unité de Recherche sur les Maladies à Vecteurs et Biodiversité, Centre International de Recherche-Développement sur l'Elevage en zone Subhumide, Bobo-Dioulasso, Burkina Faso.; Unité de Recherche « Trypanosomoses », Institut Pierre Richet, Bouaké, Côte d'Ivoire.
Gimonneau G; CIRAD, UMR INTERTRYP, Montpellier, France.; INTERTRYP, University of Montpellier, CIRAD, IRD, Montpellier, France.; Laboratoire National d'Élevage et de Recherches Vétérinaires, Service de Bio-Écologie et Pathologies Parasitaires, Dakar-Hann, Sénégal.
Kaboré J; Unité de Recherche sur les Maladies à Vecteurs et Biodiversité, Centre International de Recherche-Développement sur l'Elevage en zone Subhumide, Bobo-Dioulasso, Burkina Faso.; Unité de Formation et de Recherche en Sciences de la Vie et de la Terre, Université Nazi Boni, Bobo-Dioulasso, Burkina Faso.
Belem AGM; Institut du Développement Rural, Université Nazi Boni, Bobo-Dioulasso, Burkina Faso.
Desquesnes M; CIRAD, UMR INTERTRYP, Montpellier, France.; INTERTRYP, University of Montpellier, CIRAD, IRD, Montpellier, France.; National Veterinary School of Toulouse (ENVT), Toulouse, France.
Lejon V; INTERTRYP, University of Montpellier, CIRAD, IRD, Montpellier, France.
Koffi M; Laboratoire de Biodiversité et Gestion des Ecosystèmes Tropicaux, Unité de Recherche en Génétique et Épidémiologie Moléculaire, UFR Environnement, Université Jean Lorougnon Guédé, Daloa, Côte d'Ivoire.
Jamonneau V; Unité de Recherche « Trypanosomoses », Institut Pierre Richet, Bouaké, Côte d'Ivoire.; INTERTRYP, University of Montpellier, CIRAD, IRD, Montpellier, France.
Thévenon S; CIRAD, UMR INTERTRYP, Montpellier, France.; INTERTRYP, University of Montpellier, CIRAD, IRD, Montpellier, France.; Pokaż więcej
Źródło:: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2023 Nov 09; Vol. 17 (11), pp. e0011730. Date of Electronic Publication: 2023 Nov 09 (Print Publication: 2023).
Typ publikacji:: Journal Article
MeSH Terms:: Trypanosoma brucei brucei*
Trypanosomiasis, African*/diagnosis
Trypanosomiasis, African*/veterinary
Trypanosomiasis, African*/parasitology
Trypanosoma*
Humans ; Animals ; Swine ; Livestock ; Diagnostic Tests, Routine ; Sensitivity and Specificity

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Skocz do pozycji: 4.

Tytuł:: Tackling Sleeping Sickness: Current and Promising Therapeutics and Treatment Strategies.
Autorzy:: Jamabo M; Biotechnology Innovation Centre, Rhodes University, Makhanda 6139, South Africa.
Mahlalela M; Biotechnology Innovation Centre, Rhodes University, Makhanda 6139, South Africa.
Edkins AL; Department of Biochemistry and Microbiology, Biomedical Biotechnology Research Centre (BioBRU), Rhodes University, Makhanda 6139, South Africa.
Boshoff A; Biotechnology Innovation Centre, Rhodes University, Makhanda 6139, South Africa.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Aug 07; Vol. 24 (15). Date of Electronic Publication: 2023 Aug 07.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Trypanosomiasis, African*/diagnosis
Trypanosomiasis, African*/drug therapy
COVID-19*/epidemiology
Trypanosoma brucei brucei*/metabolism
Trypanosoma*
Animals ; Humans ; Pandemics

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Skocz do pozycji: 5.

Tytuł:: Competition among variants is predictable and contributes to the antigenic variation dynamics of African trypanosomes.
Autorzy:: Escrivani DO; Wellcome Centre for Anti-Infectives Research, School of Life Sciences, University of Dundee, Dow Street, Dundee, United Kingdom.
Scheidt V; Wellcome Centre for Anti-Infectives Research, School of Life Sciences, University of Dundee, Dow Street, Dundee, United Kingdom.
Tinti M; Wellcome Centre for Anti-Infectives Research, School of Life Sciences, University of Dundee, Dow Street, Dundee, United Kingdom.
Faria J; Wellcome Centre for Anti-Infectives Research, School of Life Sciences, University of Dundee, Dow Street, Dundee, United Kingdom.
Horn D; Wellcome Centre for Anti-Infectives Research, School of Life Sciences, University of Dundee, Dow Street, Dundee, United Kingdom.; Pokaż więcej
Źródło:: PLoS pathogens [PLoS Pathog] 2023 Jul 17; Vol. 19 (7), pp. e1011530. Date of Electronic Publication: 2023 Jul 17 (Print Publication: 2023).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Trypanosoma*
Trypanosoma brucei brucei*/metabolism
Animals ; Variant Surface Glycoproteins, Trypanosoma/genetics ; Antigenic Variation/genetics ; Immune Evasion/genetics ; Membrane Glycoproteins/metabolism ; Mammals

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Skocz do pozycji: 6.

Tytuł:: The Trypanosoma brucei MISP family of invariant proteins is co-expressed with BARP as triple helical bundle structures on the surface of salivary gland forms, but is dispensable for parasite development within the tsetse vector.
Autorzy:: Casas-Sanchez A; Department of Vector Biology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.; Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
Ramaswamy R; Department of Biochemistry and Microbiology, University of Victoria, Victoria, Canada.
Perally S; Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
Haines LR; Department of Vector Biology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
Rose C; Department of Vector Biology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
Aguilera-Flores M; Border Biomedical Research Center, Department of Biological Sciences, University of Texas at El Paso, El Paso, Texas, United States of America.
Portillo S; Border Biomedical Research Center, Department of Biological Sciences, University of Texas at El Paso, El Paso, Texas, United States of America.
Verbeelen M; Institute of Tropical Medicine, Antwerp, Belgium.
Hussain S; Institute of Tropical Medicine, Antwerp, Belgium.
Smithson L; Biological and Medical Sciences, Oxford Brookes University, Oxford, United Kingdom.
Yunta C; Department of Vector Biology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
Lehane MJ; Department of Vector Biology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
Vaughan S; Biological and Medical Sciences, Oxford Brookes University, Oxford, United Kingdom.
van den Abbeele J; Institute of Tropical Medicine, Antwerp, Belgium.
Almeida IC; Border Biomedical Research Center, Department of Biological Sciences, University of Texas at El Paso, El Paso, Texas, United States of America.
Boulanger MJ; Department of Biochemistry and Microbiology, University of Victoria, Victoria, Canada.
Acosta-Serrano Á; Department of Vector Biology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.; Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.; Pokaż więcej
Źródło:: PLoS pathogens [PLoS Pathog] 2023 Mar 30; Vol. 19 (3), pp. e1011269. Date of Electronic Publication: 2023 Mar 30 (Print Publication: 2023).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Trypanosoma brucei brucei*/genetics
Parasites*
Trypanosoma*
Animals ; Mice ; Membrane Proteins ; Alanine ; Proteomics ; Salivary Glands/parasitology ; Mammals ; Membrane Glycoproteins

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Skocz do pozycji: 7.

Tytuł:: Vector competence of sterile male Glossina fuscipes fuscipes for Trypanosoma brucei brucei: implications for the implementation of the sterile insect technique in a sleeping sickness focus in Chad.
Autorzy:: Mahamat MH; Institut de Recherche en Elevage pour le Développement (IRED), Ndjaména, Chad.
Ségard A; Université de Montpellier, Cirad, IRD, Intertryp, Montpellier, France.
Rayaisse JB; Centre International de Recherche-Développement sur l'Elevage en Zone Subhumide (CIRDES), Bobo-Dioulasso, Burkina Faso.
Argiles-Herrero R; Joint Food and Agriculture Organization of the United Nations/International Atomic Energy Agency Centre of Nuclear Techniques in Food and Agriculture, Insect Pest Control Sub-programme, A-1400, Vienna, Austria.
Parker AG; Joint Food and Agriculture Organization of the United Nations/International Atomic Energy Agency Centre of Nuclear Techniques in Food and Agriculture, Insect Pest Control Sub-programme, A-1400, Vienna, Austria.
Solano P; Université de Montpellier, Cirad, IRD, Intertryp, Montpellier, France.
Abd-Alla AMM; Joint Food and Agriculture Organization of the United Nations/International Atomic Energy Agency Centre of Nuclear Techniques in Food and Agriculture, Insect Pest Control Sub-programme, A-1400, Vienna, Austria.
Bouyer J; Joint Food and Agriculture Organization of the United Nations/International Atomic Energy Agency Centre of Nuclear Techniques in Food and Agriculture, Insect Pest Control Sub-programme, A-1400, Vienna, Austria.; Université de Montpellier, Cirad, INRAE, ASTRE, Montpellier, France.
Ravel S; Université de Montpellier, Cirad, IRD, Intertryp, Montpellier, France. .; Pokaż więcej
Źródło:: Parasites & vectors [Parasit Vectors] 2023 Mar 22; Vol. 16 (1), pp. 111. Date of Electronic Publication: 2023 Mar 22.
Typ publikacji:: Journal Article
MeSH Terms:: Trypanosomiasis, African*/epidemiology
Trypanosomiasis, African*/prevention & control
Trypanosomiasis, African*/parasitology
Tsetse Flies*/parasitology
Trypanosoma brucei brucei*
Trypanocidal Agents*
Trypanosoma*
Infertility, Male*
Animals ; Male ; Humans ; Chad/epidemiology ; Insecta

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Skocz do pozycji: 8.

Tytuł:: Structural similarities between the metacyclic and bloodstream form variant surface glycoproteins of the African trypanosome.
Autorzy:: Chandra M; Division of Structural Biology of Infection and Immunity, German Cancer Research Center, Heidelberg, Germany.; Division of Immune Diversity, German Cancer Research Center, Heidelberg, Germany.
Đaković S; Division of Structural Biology of Infection and Immunity, German Cancer Research Center, Heidelberg, Germany.
Foti K; Division of Structural Biology of Infection and Immunity, German Cancer Research Center, Heidelberg, Germany.
Zeelen JP; Division of Structural Biology of Infection and Immunity, German Cancer Research Center, Heidelberg, Germany.
van Straaten M; Division of Structural Biology of Infection and Immunity, German Cancer Research Center, Heidelberg, Germany.
Aresta-Branco F; Division of Structural Biology of Infection and Immunity, German Cancer Research Center, Heidelberg, Germany.; Division of Immune Diversity, German Cancer Research Center, Heidelberg, Germany.
Tihon E; Institut Pasteur, Université Paris Cité, Trypanosome Molecular Biology, Department of Parasites and Insect Vectors, Paris, France.
Lübbehusen N; Centre for Molecular Biology at the University of Heidelberg (ZMBH), DKFZ-ZMBH Alliance, Heidelberg, Germany.
Ruppert T; Centre for Molecular Biology at the University of Heidelberg (ZMBH), DKFZ-ZMBH Alliance, Heidelberg, Germany.
Glover L; Institut Pasteur, Université Paris Cité, Trypanosome Molecular Biology, Department of Parasites and Insect Vectors, Paris, France.
Papavasiliou FN; Division of Immune Diversity, German Cancer Research Center, Heidelberg, Germany.
Stebbins CE; Division of Structural Biology of Infection and Immunity, German Cancer Research Center, Heidelberg, Germany.; Pokaż więcej
Źródło:: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2023 Feb 13; Vol. 17 (2), pp. e0011093. Date of Electronic Publication: 2023 Feb 13 (Print Publication: 2023).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Trypanosoma brucei brucei*/genetics
Trypanosoma*
Tsetse Flies*/parasitology
Trypanosomiasis, African*/parasitology
Animals ; Membrane Glycoproteins/metabolism ; Variant Surface Glycoproteins, Trypanosoma/genetics ; Mammals

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Skocz do pozycji: 9.

Tytuł:: Drugging the Undruggable Trypanosoma brucei Monothiol Glutaredoxin 1.
Autorzy:: Favaro A; Molecular Modeling Section (MMS), Department of Pharmaceutical and Pharmacological Sciences, University of Padova, via Marzolo 5, 35131 Padova, Italy.
Bolcato G; Molecular Modeling Section (MMS), Department of Pharmaceutical and Pharmacological Sciences, University of Padova, via Marzolo 5, 35131 Padova, Italy.
Comini MA; Laboratory Redox Biology of Trypanosomes, Institut Pasteur de Montevideo, Mataojo 2020, Montevideo 11400, Uruguay.
Moro S; Molecular Modeling Section (MMS), Department of Pharmaceutical and Pharmacological Sciences, University of Padova, via Marzolo 5, 35131 Padova, Italy.
Bellanda M; Department of Chemical Sciences, University of Padova, via Marzolo 1, 35131 Padova, Italy.; Consiglio Nazionale delle Ricerche, Institute of Biomolecular Chemistry, 35131 Padova, Italy.
Sturlese M; Molecular Modeling Section (MMS), Department of Pharmaceutical and Pharmacological Sciences, University of Padova, via Marzolo 5, 35131 Padova, Italy.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2023 Jan 28; Vol. 28 (3). Date of Electronic Publication: 2023 Jan 28.
Typ publikacji:: Journal Article
MeSH Terms:: Trypanosoma brucei brucei*/metabolism
Trypanosoma*/metabolism
Trypanosomiasis, African*/drug therapy
Humans ; Female ; Animals ; Cattle ; Horses ; Glutaredoxins/chemistry ; Glutathione/metabolism

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Skocz do pozycji: 10.

Tytuł:: Two Tags in One Probe: Combining Fluorescence- and Biotin-based Detection of the Trypanosomal Cysteine Protease Rhodesain.
Autorzy:: Lemke C; Pharmaceutical Institute, Department of Pharmaceutical & Medicinal Chemistry, University of Bonn, An der Immenburg 4, 53121, Bonn, Germany.
Jílková A; Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Flemingovo n. 2, 16610, Prague, Czech Republic.
Ferber D; Pharmaceutical Institute, Department of Pharmaceutical & Medicinal Chemistry, University of Bonn, An der Immenburg 4, 53121, Bonn, Germany.
Braune A; Research Group Intestinal Microbiology, German Institute of Human Nutrition Potsdam-Rehbruecke, Arthur-Scheunert-Allee 114-116, 14558, Nuthetal, Germany.
On A; Pharmaceutical Institute, Department of Pharmaceutical & Medicinal Chemistry, University of Bonn, An der Immenburg 4, 53121, Bonn, Germany.
Johe P; Institute of Pharmaceutical and Biomedical Sciences (IPBS), Johannes Gutenberg University of Mainz, Staudingerweg 5, 55128, Mainz, Germany.
Zíková A; Biology Centre CAS, Institute of Parasitology, University of South Bohemia, Faculty of Science, Branišovská 1160/31, 37005, České Budějovice, Czech Republic.
Schirmeister T; Institute of Pharmaceutical and Biomedical Sciences (IPBS), Johannes Gutenberg University of Mainz, Staudingerweg 5, 55128, Mainz, Germany.
Mareš M; Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Flemingovo n. 2, 16610, Prague, Czech Republic.
Horn M; Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Flemingovo n. 2, 16610, Prague, Czech Republic.
Gütschow M; Pharmaceutical Institute, Department of Pharmaceutical & Medicinal Chemistry, University of Bonn, An der Immenburg 4, 53121, Bonn, Germany.; Pokaż więcej
Źródło:: Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2022 Nov 07; Vol. 28 (62), pp. e202201636. Date of Electronic Publication: 2022 Sep 07.
Typ publikacji:: Journal Article
MeSH Terms:: Cysteine Proteases*
Trypanosoma brucei brucei*
Trypanosoma*
Biotin ; Fluorescence ; Proteomics ; Structure-Activity Relationship

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Skocz do pozycji: 11.

Tytuł:: Pseudokinase NRP1 facilitates endocytosis of transferrin in the African trypanosome.
Autorzy:: Kumar G; Department of Molecular and Cellular Biology, Kennesaw State University, Kennesaw, Georgia.
Thomas B; Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, Georgia.
Mensa-Wilmot K; Department of Molecular and Cellular Biology, Kennesaw State University, Kennesaw, Georgia. .; Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, Georgia. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2022 Nov 03; Vol. 12 (1), pp. 18572. Date of Electronic Publication: 2022 Nov 03.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: Trypanosoma*/metabolism
Trypanosoma brucei brucei*/metabolism
Trypanosomiasis, African*/parasitology
Animals ; Cattle ; Humans ; Endocytosis/genetics ; Endosomes/metabolism ; NIMA-Related Kinases/metabolism ; Protein Kinases/metabolism ; Receptors, Transferrin/metabolism ; Transferrin/genetics ; Transferrin/metabolism ; Neuropilin-1/metabolism

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Skocz do pozycji: 12.

Tytuł:: Preliminary Structure-Activity Relationship Study of the MMV Pathogen Box Compound MMV675968 (2,4-Diaminoquinazoline) Unveils Novel Inhibitors of Trypanosoma brucei brucei .
Autorzy:: Dize D; Antimicrobial and Biocontrol Agents Unit (AmBcAU), Laboratory for Phytobiochemistry and Medicinal Plants Studies, Department of Biochemistry, Faculty of Science, University of Yaoundé I, Yaoundé P.O. Box 812, Cameroon.
Tata RB; Research Unit in Bioinformatics (RUBi), Department of Biochemistry and Microbiology, Rhodes University, Grahamstown 6139, South Africa.
Keumoe R; Antimicrobial and Biocontrol Agents Unit (AmBcAU), Laboratory for Phytobiochemistry and Medicinal Plants Studies, Department of Biochemistry, Faculty of Science, University of Yaoundé I, Yaoundé P.O. Box 812, Cameroon.
Kouipou Toghueo RM; Antimicrobial and Biocontrol Agents Unit (AmBcAU), Laboratory for Phytobiochemistry and Medicinal Plants Studies, Department of Biochemistry, Faculty of Science, University of Yaoundé I, Yaoundé P.O. Box 812, Cameroon.
Tchatat MB; Antimicrobial and Biocontrol Agents Unit (AmBcAU), Laboratory for Phytobiochemistry and Medicinal Plants Studies, Department of Biochemistry, Faculty of Science, University of Yaoundé I, Yaoundé P.O. Box 812, Cameroon.
Njanpa CN; Antimicrobial and Biocontrol Agents Unit (AmBcAU), Laboratory for Phytobiochemistry and Medicinal Plants Studies, Department of Biochemistry, Faculty of Science, University of Yaoundé I, Yaoundé P.O. Box 812, Cameroon.
Tchuenguia VC; Antimicrobial and Biocontrol Agents Unit (AmBcAU), Laboratory for Phytobiochemistry and Medicinal Plants Studies, Department of Biochemistry, Faculty of Science, University of Yaoundé I, Yaoundé P.O. Box 812, Cameroon.
Yamthe LT; Antimicrobial and Biocontrol Agents Unit (AmBcAU), Laboratory for Phytobiochemistry and Medicinal Plants Studies, Department of Biochemistry, Faculty of Science, University of Yaoundé I, Yaoundé P.O. Box 812, Cameroon.
Fokou PVT; Antimicrobial and Biocontrol Agents Unit (AmBcAU), Laboratory for Phytobiochemistry and Medicinal Plants Studies, Department of Biochemistry, Faculty of Science, University of Yaoundé I, Yaoundé P.O. Box 812, Cameroon.
Laleu B; Medicines for Malaria Venture, Route de Pré-Bois 20, 1215 Meyrin, Switzerland.
Duffy J; Medicines for Malaria Venture, Route de Pré-Bois 20, 1215 Meyrin, Switzerland.
Bishop OT; Research Unit in Bioinformatics (RUBi), Department of Biochemistry and Microbiology, Rhodes University, Grahamstown 6139, South Africa.
Boyom FF; Antimicrobial and Biocontrol Agents Unit (AmBcAU), Laboratory for Phytobiochemistry and Medicinal Plants Studies, Department of Biochemistry, Faculty of Science, University of Yaoundé I, Yaoundé P.O. Box 812, Cameroon.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2022 Oct 04; Vol. 27 (19). Date of Electronic Publication: 2022 Oct 04.
Typ publikacji:: Journal Article
MeSH Terms:: Trypanocidal Agents*/chemistry
Trypanosoma*/metabolism
Trypanosoma brucei brucei*
Trypanosomiasis, African*/drug therapy
Animals ; Humans ; Iron/therapeutic use ; Ligands ; Quinazolines ; Structure-Activity Relationship ; Tetrahydrofolate Dehydrogenase/metabolism

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Skocz do pozycji: 13.

Tytuł:: A novel lipase with dual localisation in Trypanosoma brucei.
Autorzy:: Monic SG; Laboratoire de Microbiologie Fondamentale et Pathogénicité (MFP), CNRS UMR-5234, Université de Bordeaux, Bordeaux, France.
Lamy A; Laboratoire de Microbiologie Fondamentale et Pathogénicité (MFP), CNRS UMR-5234, Université de Bordeaux, Bordeaux, France.
Thonnus M; Laboratoire de Microbiologie Fondamentale et Pathogénicité (MFP), CNRS UMR-5234, Université de Bordeaux, Bordeaux, France.
Bizarra-Rebelo T; Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal.
Bringaud F; Laboratoire de Microbiologie Fondamentale et Pathogénicité (MFP), CNRS UMR-5234, Université de Bordeaux, Bordeaux, France.
Smith TK; Biomedical Sciences Research Complex, University of St Andrews, St Andrews, UK.
Figueiredo LM; Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal.
Rivière L; Laboratoire de Microbiologie Fondamentale et Pathogénicité (MFP), CNRS UMR-5234, Université de Bordeaux, Bordeaux, France. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2022 Mar 19; Vol. 12 (1), pp. 4766. Date of Electronic Publication: 2022 Mar 19.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Trypanosoma*/genetics
Trypanosoma brucei brucei*/genetics
Trypanosoma brucei brucei*/metabolism
Humans ; Lipase/genetics ; Lipase/metabolism ; Microbodies/metabolism ; Phospholipases/genetics ; Phospholipases/metabolism

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Skocz do pozycji: 14.

Tytuł:: Targeting the tsetse-trypanosome interplay using genetically engineered Sodalis glossinidius.
Autorzy:: De Vooght L; Department of Biomedical Sciences, Trypanosoma Unit, Institute of Tropical Medicine Antwerp, Antwerp, Belgium.; Laboratory of Microbiology, Parasitology and Hygiene (LMPH), University of Antwerp, Wilrijk, Belgium.
De Ridder K; Department of Biomedical Sciences, Trypanosoma Unit, Institute of Tropical Medicine Antwerp, Antwerp, Belgium.
Hussain S; Unit of Cellular and Molecular Immunology, Vrije Universiteit Brussel, Brussels, Belgium.
Stijlemans B; Unit of Cellular and Molecular Immunology, Vrije Universiteit Brussel, Brussels, Belgium.; Myeloid Cell Immunology Lab, VIB Inflammation Research Center, Gent, Belgium.
De Baetselier P; Unit of Cellular and Molecular Immunology, Vrije Universiteit Brussel, Brussels, Belgium.
Caljon G; Laboratory of Microbiology, Parasitology and Hygiene (LMPH), University of Antwerp, Wilrijk, Belgium.
Van Den Abbeele J; Department of Biomedical Sciences, Trypanosoma Unit, Institute of Tropical Medicine Antwerp, Antwerp, Belgium.; Pokaż więcej
Źródło:: PLoS pathogens [PLoS Pathog] 2022 Mar 10; Vol. 18 (3), pp. e1010376. Date of Electronic Publication: 2022 Mar 10 (Print Publication: 2022).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Single-Domain Antibodies*/metabolism
Trypanosoma*
Trypanosoma brucei brucei*/genetics
Tsetse Flies*/parasitology
Animals ; Enterobacteriaceae/genetics ; Enterobacteriaceae/metabolism ; Symbiosis
SCR Organism:: Sodalis glossinidius

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Tytuł:: Single-cell transcriptomics reveals expression profiles of Trypanosoma brucei sexual stages.
Autorzy:: Howick VM; Institute of Biodiversity, Animal Health, and Comparative Medicine, University of Glasgow, Glasgow, United Kingdom.; Wellcome Centre for Integrative Parasitology, University of Glasgow, Glasgow, United Kingdom.; Parasites and Microbes Programme, Wellcome Sanger Institute, Hinxton, United Kingdom.
Peacock L; School of Biological Sciences, University of Bristol, Bristol, United Kingdom.; Bristol Veterinary School, University of Bristol, Langford, United Kingdom.
Kay C; School of Biological Sciences, University of Bristol, Bristol, United Kingdom.
Collett C; School of Biological Sciences, University of Bristol, Bristol, United Kingdom.
Gibson W; School of Biological Sciences, University of Bristol, Bristol, United Kingdom.
Lawniczak MKN; Parasites and Microbes Programme, Wellcome Sanger Institute, Hinxton, United Kingdom.; Pokaż więcej
Źródło:: PLoS pathogens [PLoS Pathog] 2022 Mar 07; Vol. 18 (3), pp. e1010346. Date of Electronic Publication: 2022 Mar 07 (Print Publication: 2022).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Trypanosoma*/genetics
Trypanosoma brucei brucei*/genetics
Trypanosomiasis, African*/parasitology
Tsetse Flies*/genetics
Tsetse Flies*/parasitology
Animals ; Transcriptome

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Skocz do pozycji: 16.

Tytuł:: Redistribution of FLAgellar Member 8 during the trypanosome life cycle: Consequences for cell fate prediction.
Autorzy:: Calvo-Álvarez E; Trypanosome Cell Biology Unit, Institut Pasteur and INSERM U1201, Paris, France.; Trypanosome Transmission Group, Institut Pasteur, Paris, France.
Bonnefoy S; Trypanosome Cell Biology Unit, Institut Pasteur and INSERM U1201, Paris, France.
Salles A; Unit of Technology and Service Photonic BioImaging (UTechS PBI), C2RT, Institut Pasteur, Paris, France.
Benson FE; Division of Biomedical and Life Sciences, Lancaster University, Lancaster, UK.
McKean PG; Division of Biomedical and Life Sciences, Lancaster University, Lancaster, UK.
Bastin P; Trypanosome Cell Biology Unit, Institut Pasteur and INSERM U1201, Paris, France.
Rotureau B; Trypanosome Cell Biology Unit, Institut Pasteur and INSERM U1201, Paris, France.; Trypanosome Transmission Group, Institut Pasteur, Paris, France.; Pokaż więcej
Źródło:: Cellular microbiology [Cell Microbiol] 2021 Sep; Vol. 23 (9), pp. e13347. Date of Electronic Publication: 2021 May 14.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Trypanosoma*
Trypanosoma brucei brucei*
Tsetse Flies*
Animals ; Cell Differentiation ; Flagella ; Life Cycle Stages ; Protozoan Proteins

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Tytuł:: Procyclic trypanosomes recycle glucose catabolites and TCA cycle intermediates to stimulate growth in the presence of physiological amounts of proline.
Autorzy:: Villafraz O; Univ. Bordeaux, CNRS, Microbiologie Fondamentale et Pathogénicité (MFP), UMR 5234, Bordeaux, France.
Biran M; Univ. Bordeaux, CNRS, Centre de Résonance Magnétique des Systèmes Biologiques (CRMSB), UMR 5536, Bordeaux, France.
Pineda E; Univ. Bordeaux, CNRS, Microbiologie Fondamentale et Pathogénicité (MFP), UMR 5234, Bordeaux, France.
Plazolles N; Univ. Bordeaux, CNRS, Microbiologie Fondamentale et Pathogénicité (MFP), UMR 5234, Bordeaux, France.
Cahoreau E; Toulouse Biotechnology Institute, TBI-INSA de Toulouse INSA/CNRS 5504-UMR INSA/INRA 792, Toulouse, France.; MetaToul-MetaboHub, National Infrastructure of Metabolomics and Fluxomics, Toulouse, France.
Ornitz Oliveira Souza R; Laboratory of Biochemistry of Tryps-LaBTryps, Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.
Thonnus M; Univ. Bordeaux, CNRS, Microbiologie Fondamentale et Pathogénicité (MFP), UMR 5234, Bordeaux, France.
Allmann S; Fakultät für Biologie, Genetik, Ludwig-Maximilians-Universität München, Grosshadernerstrasse 2-4, Martinsried, Germany.
Tetaud E; Univ. Bordeaux, CNRS, Microbiologie Fondamentale et Pathogénicité (MFP), UMR 5234, Bordeaux, France.
Rivière L; Univ. Bordeaux, CNRS, Microbiologie Fondamentale et Pathogénicité (MFP), UMR 5234, Bordeaux, France.
Silber AM; Laboratory of Biochemistry of Tryps-LaBTryps, Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.
Barrett MP; Wellcome Centre for Integrative Parasitology, Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom.; Glasgow Polyomics, Wolfson Wohl Cancer Research Centre, Garscube Campus, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom.
Zíková A; Institute of Parasitology, Biology Center, Czech Academy of Sciences, České Budějovice, Czech Republic.
Boshart M; Fakultät für Biologie, Genetik, Ludwig-Maximilians-Universität München, Grosshadernerstrasse 2-4, Martinsried, Germany.
Portais JC; Toulouse Biotechnology Institute, TBI-INSA de Toulouse INSA/CNRS 5504-UMR INSA/INRA 792, Toulouse, France.; MetaToul-MetaboHub, National Infrastructure of Metabolomics and Fluxomics, Toulouse, France.; RESTORE, Université de Toulouse, Inserm U1031, CNRS 5070, UPS, EFS, ENVT, Toulouse, France.
Bringaud F; Univ. Bordeaux, CNRS, Microbiologie Fondamentale et Pathogénicité (MFP), UMR 5234, Bordeaux, France.; Pokaż więcej
Źródło:: PLoS pathogens [PLoS Pathog] 2021 Mar 01; Vol. 17 (3), pp. e1009204. Date of Electronic Publication: 2021 Mar 01 (Print Publication: 2021).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Glucose/*metabolism
Proline/*pharmacology
Trypanosoma/*drug effects
Trypanosoma brucei brucei/*drug effects
Tsetse Flies/*drug effects
Animals ; Citric Acid Cycle/drug effects ; Insect Vectors/parasitology ; Oxidation-Reduction/drug effects ; Proline/metabolism ; RNA Interference/physiology ; Trypanosoma/metabolism ; Trypanosoma brucei brucei/metabolism ; Trypanosomiasis, African/drug therapy ; Tsetse Flies/parasitology

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Skocz do pozycji: 18.

Tytuł:: Signatures of hybridization in Trypanosoma brucei.
Autorzy:: Kay C; School of Biological Sciences, University of Bristol, Bristol, United Kingdom.
Peacock L; School of Biological Sciences, University of Bristol, Bristol, United Kingdom.; Bristol Veterinary School, University of Bristol, Bristol, United Kingdom.
Williams TA; School of Biological Sciences, University of Bristol, Bristol, United Kingdom.
Gibson W; School of Biological Sciences, University of Bristol, Bristol, United Kingdom.; Pokaż więcej
Źródło:: PLoS pathogens [PLoS Pathog] 2022 Feb 09; Vol. 18 (2), pp. e1010300. Date of Electronic Publication: 2022 Feb 09 (Print Publication: 2022).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: DNA, Kinetoplast/*genetics
Hybridization, Genetic/*genetics
Trypanosoma/*genetics
Trypanosoma brucei brucei/*genetics
Animals ; DNA, Mitochondrial/genetics ; DNA, Protozoan/genetics ; Genotype ; Humans ; Trypanosomiasis, African/genetics

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Skocz do pozycji: 19.

Tytuł:: Catalase compromises the development of the insect and mammalian stages of Trypanosoma brucei.
Autorzy:: Horáková E; Institute of Parasitology, Biology Centre, Czech Academy of Sciences, České Budějovice (Budweis), Czech Republic.
Faktorová D; Institute of Parasitology, Biology Centre, Czech Academy of Sciences, České Budějovice (Budweis), Czech Republic.; Faculty of Science, University of South Bohemia, České Budějovice (Budweis), Czech Republic.
Kraeva N; Life Science Research Centre, Faculty of Science, University of Ostrava, Czech Republic.
Kaur B; Institute of Parasitology, Biology Centre, Czech Academy of Sciences, České Budějovice (Budweis), Czech Republic.; Faculty of Science, University of South Bohemia, České Budějovice (Budweis), Czech Republic.
Van Den Abbeele J; Department of Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.
Yurchenko V; Life Science Research Centre, Faculty of Science, University of Ostrava, Czech Republic.; Martsinovsky Institute of Medical Parasitology, Tropical and Vector Borne Diseases, Sechenov University, Moscow, Russia.
Lukeš J; Institute of Parasitology, Biology Centre, Czech Academy of Sciences, České Budějovice (Budweis), Czech Republic.; Faculty of Science, University of South Bohemia, České Budějovice (Budweis), Czech Republic.; Pokaż więcej
Źródło:: The FEBS journal [FEBS J] 2020 Mar; Vol. 287 (5), pp. 964-977. Date of Electronic Publication: 2019 Oct 29.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Catalase/*metabolism
Insecta/*drug effects
Insecta/*metabolism
Trypanosoma/*metabolism
Trypanosoma brucei brucei/*metabolism
Animals ; Hydrogen Peroxide/pharmacology ; Insecta/growth & development ; Trypanosoma/drug effects ; Trypanosoma brucei brucei/drug effects

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Tytuł:: Tsetse salivary glycoproteins are modified with paucimannosidic N-glycans, are recognised by C-type lectins and bind to trypanosomes.
Autorzy:: Kozak RP; Ludger Ltd., Culham Science Centre, Oxford, United Kingdom.
Mondragon-Shem K; Department of Vector Biology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
Williams C; Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
Rose C; Department of Vector Biology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
Perally S; Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
Caljon G; Laboratory of Microbiology, Parasitology and Hygiene (LMPH), University of Antwerp, Antwerp, Belgium.
Van Den Abbeele J; Department of Biomedical Sciences, Institute of Tropical Medicine Antwerp, Antwerp, Belgium.
Wongtrakul-Kish K; Ludger Ltd., Culham Science Centre, Oxford, United Kingdom.
Gardner RA; Ludger Ltd., Culham Science Centre, Oxford, United Kingdom.
Spencer D; Ludger Ltd., Culham Science Centre, Oxford, United Kingdom.
Lehane MJ; Department of Vector Biology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
Acosta-Serrano Á; Department of Vector Biology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.; Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.; Pokaż więcej
Źródło:: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2021 Feb 02; Vol. 15 (2), pp. e0009071. Date of Electronic Publication: 2021 Feb 02 (Print Publication: 2021).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Glycoproteins/*metabolism
Lectins, C-Type/*metabolism
Polysaccharides/*metabolism
Salivary Proteins and Peptides/*metabolism
Trypanosoma/*metabolism
Tsetse Flies/*parasitology
Animals ; Chromatography, Liquid ; Concanavalin A ; Glycoside Hydrolases ; Insect Vectors/parasitology ; Saliva ; Salivary Glands/parasitology ; Tandem Mass Spectrometry ; Trypanosoma brucei brucei/genetics ; Trypanosomiasis, African/parasitology

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