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Wyszukujesz frazę ""Trypanosoma brucei gambiense"" wg kryterium: Temat


Tytuł:
Melarsoprol sensitivity profile of Trypanosoma brucei gambiense isolates from cured and relapsed sleeping sickness patients from the Democratic Republic of the Congo.
Autorzy:
Pyana Pati P; Département de Parasitologie, Institut National de Recherche Biomédicale, Kinshasa Gombe, Democratic Republic of the Congo.
Van Reet N; Department of Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.
Mumba Ngoyi D; Département de Parasitologie, Institut National de Recherche Biomédicale, Kinshasa Gombe, Democratic Republic of the Congo.
Ngay Lukusa I; Département de Parasitologie, Institut National de Recherche Biomédicale, Kinshasa Gombe, Democratic Republic of the Congo.
Karhemere Bin Shamamba S; Département de Parasitologie, Institut National de Recherche Biomédicale, Kinshasa Gombe, Democratic Republic of the Congo.
Büscher P; Department of Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.
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Źródło:
PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2014 Oct 02; Vol. 8 (10), pp. e3212. Date of Electronic Publication: 2014 Oct 02 (Print Publication: 2014).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Aquaglyceroporins/*genetics
Melarsoprol/*pharmacology
Trypanocidal Agents/*pharmacology
Trypanosoma brucei gambiense/*drug effects
Trypanosomiasis, African/*parasitology
Adult ; Animals ; Base Sequence ; DNA, Protozoan/chemistry ; DNA, Protozoan/isolation & purification ; Democratic Republic of the Congo ; Drug Resistance/genetics ; Female ; Genotype ; Humans ; Melarsoprol/therapeutic use ; Mice ; Molecular Sequence Data ; Mutant Chimeric Proteins/genetics ; Mutation ; Pentamidine/pharmacology ; Phenotype ; Recurrence ; Sequence Analysis, DNA ; Trypanocidal Agents/therapeutic use ; Trypanosoma brucei gambiense/genetics ; Trypanosomiasis, African/drug therapy
Czasopismo naukowe
Tytuł:
Aquaporin 2 mutations in Trypanosoma brucei gambiense field isolates correlate with decreased susceptibility to pentamidine and melarsoprol.
Autorzy:
Graf FE; Swiss Tropical and Public Health Institute, Basel, Switzerland ; University of Basel, Basel, Switzerland.
Ludin P
Wenzler T
Kaiser M
Brun R
Pyana PP
Büscher P
de Koning HP
Horn D
Mäser P
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Źródło:
PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2013 Oct 10; Vol. 7 (10), pp. e2475. Date of Electronic Publication: 2013 Oct 10 (Print Publication: 2013).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Drug Resistance*
Mutation*
Aquaporin 2/*genetics
Melarsoprol/*pharmacology
Pentamidine/*pharmacology
Trypanocidal Agents/*pharmacology
Trypanosoma brucei gambiense/*drug effects
Aquaporin 2/metabolism ; DNA, Protozoan/chemistry ; DNA, Protozoan/genetics ; Humans ; Molecular Sequence Data ; Protozoan Proteins/genetics ; Sequence Analysis, DNA ; Trypanosoma brucei gambiense/genetics ; Trypanosoma brucei gambiense/isolation & purification ; Trypanosomiasis, African/parasitology
Czasopismo naukowe
Tytuł:
Efficacy of 10-day melarsoprol schedule 2 years after treatment for late-stage gambiense sleeping sickness.
Autorzy:
Schmid C; Swiss Tropical Institute, 4002 Basel, Switzerland. />Nkunku S
Merolle A
Vounatsou P
Burri C
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Źródło:
Lancet (London, England) [Lancet] 2004 Aug 28-Sep 3; Vol. 364 (9436), pp. 789-90.
Typ publikacji:
Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms:
Trypanosoma brucei gambiense*/isolation & purification
Melarsoprol/*administration & dosage
Trypanocidal Agents/*administration & dosage
Trypanosomiasis, African/*drug therapy
Animals ; Drug Administration Schedule ; Follow-Up Studies ; Humans ; Recurrence ; Risk Factors ; Trypanosomiasis, African/parasitology
Czasopismo naukowe
Tytuł:
Efficacy of new, concise schedule for melarsoprol in treatment of sleeping sickness caused by Trypanosoma brucei gambiense: a randomised trial.
Autorzy:
Burri C; Swiss Tropical Institute, Basel. />Nkunku S
Merolle A
Smith T
Blum J
Brun R
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Źródło:
Lancet (London, England) [Lancet] 2000 Apr 22; Vol. 355 (9213), pp. 1419-25.
Typ publikacji:
Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial
MeSH Terms:
Trypanosoma brucei gambiense*
Melarsoprol/*administration & dosage
Trypanocidal Agents/*administration & dosage
Trypanosomiasis, African/*drug therapy
Adult ; Angola/epidemiology ; Animals ; Brain Diseases/parasitology ; Drug Administration Schedule ; Female ; Humans ; Injections, Intramuscular ; Length of Stay/statistics & numerical data ; Male ; Melarsoprol/adverse effects ; Middle Aged ; Severity of Illness Index ; Time Factors ; Treatment Outcome ; Trypanocidal Agents/adverse effects ; Trypanosomiasis, African/complications ; Trypanosomiasis, African/mortality ; Trypanosomiasis, African/parasitology
Czasopismo naukowe
Tytuł:
Isolation of Trypanosoma brucei gambiense from cured and relapsed sleeping sickness patients and adaptation to laboratory mice.
Autorzy:
Pyana PP; Institut National de Recherche Biomédicale, Kinshasa Gombe, Democratic Republic of the Congo.
Ngay Lukusa I
Mumba Ngoyi D
Van Reet N
Kaiser M
Karhemere Bin Shamamba S
Büscher P
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Źródło:
PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2011 Apr 19; Vol. 5 (4), pp. e1025. Date of Electronic Publication: 2011 Apr 19.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antiprotozoal Agents/*administration & dosage
Melarsoprol/*administration & dosage
Trypanosoma brucei gambiense/*growth & development
Trypanosoma brucei gambiense/*isolation & purification
Trypanosomiasis, African/*drug therapy
Trypanosomiasis, African/*parasitology
Adaptation, Biological ; Animals ; Blood/parasitology ; Cerebrospinal Fluid/parasitology ; Female ; Humans ; Male ; Mice ; Recurrence
Czasopismo naukowe
Tytuł:
Trypanosomiasis relapse after melarsoprol therapy, Democratic Republic of Congo, 1982-2001.
Autorzy:
Pépin J; Centre for International Health and Department of Microbiology and Infectious Diseases, University of Sherbrooke, Sherbrooke, Quebec, Canada.
Mpia B
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Źródło:
Emerging infectious diseases [Emerg Infect Dis] 2005 Jun; Vol. 11 (6), pp. 921-7.
Typ publikacji:
Journal Article
MeSH Terms:
Melarsoprol/*therapeutic use
Trypanocidal Agents/*therapeutic use
Trypanosomiasis, African/*drug therapy
Trypanosomiasis, African/*prevention & control
Adolescent ; Adult ; Animals ; Democratic Republic of the Congo ; Female ; Humans ; Male ; Melarsoprol/administration & dosage ; Middle Aged ; Secondary Prevention ; Treatment Failure ; Trypanocidal Agents/administration & dosage ; Trypanosoma brucei gambiense/drug effects ; Trypanosomiasis, African/parasitology
Czasopismo naukowe
Tytuł:
Veterinary link to drug resistance in human African trypanosomiasis?
Autorzy:
Barrett MP; Division of Infection and Immunity, Institute of Biomedical and Life Sciences, University of Glasgow, G12 8QQ, Glasgow, UK.
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Źródło:
Lancet (London, England) [Lancet] 2001 Aug 25; Vol. 358 (9282), pp. 603-4.
Typ publikacji:
Comment; Journal Article
MeSH Terms:
Melarsoprol/*pharmacology
Trypanocidal Agents/*pharmacology
Trypanosoma brucei gambiense/*drug effects
Trypanosomiasis, African/*drug therapy
Trypanosomiasis, African/*veterinary
Animals ; Cattle ; Drug Resistance ; Humans ; Trypanosoma brucei rhodesiense
Czasopismo naukowe
Tytuł:
Chimerization at the AQP2–AQP3 locus is the genetic basis of melarsoprol–pentamidine cross-resistance in clinical Trypanosoma brucei gambiense isolates
Autorzy:
Fabrice E. Graf
Nicola Baker
Jane C. Munday
Harry P. de Koning
David Horn
Pascal Mäser
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Temat:
Human African trypanosomiasis
Sleeping sickness
Trypanosoma brucei gambiense
Drug resistance
Melarsoprol
Pentamidine
Aquaporin
Reverse genetics
Infectious and parasitic diseases
RC109-216
Źródło:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 5, Iss 2, Pp 65-68 (2015)
Opis pliku:
electronic resource
Relacje:
http://www.sciencedirect.com/science/article/pii/S2211320715000081; https://doaj.org/toc/2211-3207
Dostęp URL:
https://doaj.org/article/20954e2ab8b0455dba5be27f96e76043  Link otwiera się w nowym oknie
Czasopismo naukowe

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