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Wyszukujesz frazę ""Trypanosoma brucei gambiense"" wg kryterium: Temat


Tytuł :
Quantifying epidemiological drivers of gambiense human African Trypanosomiasis across the Democratic Republic of Congo.
Autorzy :
Crump RE; Zeeman Institute for System Biology and Infectious Disease Epidemiology Research, The University of Warwick, Coventry, United Kingdom.; Mathematics Institute, The University of Warwick, Coventry, United Kingdom.; The School of Life Sciences, The University of Warwick, Coventry, United Kingdom.
Huang CI; Zeeman Institute for System Biology and Infectious Disease Epidemiology Research, The University of Warwick, Coventry, United Kingdom.; Mathematics Institute, The University of Warwick, Coventry, United Kingdom.
Knock ES; Zeeman Institute for System Biology and Infectious Disease Epidemiology Research, The University of Warwick, Coventry, United Kingdom.; The Department of Statistics, The University of Warwick, Coventry, United Kingdom.
Spencer SEF; Zeeman Institute for System Biology and Infectious Disease Epidemiology Research, The University of Warwick, Coventry, United Kingdom.; The Department of Statistics, The University of Warwick, Coventry, United Kingdom.
Brown PE; Zeeman Institute for System Biology and Infectious Disease Epidemiology Research, The University of Warwick, Coventry, United Kingdom.; Mathematics Institute, The University of Warwick, Coventry, United Kingdom.
Mwamba Miaka E; Programme National de Lutte contre la Trypanosomiase Humaine Africaine (PNLTHA), Kinshasa, D.R.C.
Shampa C; Programme National de Lutte contre la Trypanosomiase Humaine Africaine (PNLTHA), Kinshasa, D.R.C.
Keeling MJ; Zeeman Institute for System Biology and Infectious Disease Epidemiology Research, The University of Warwick, Coventry, United Kingdom.; Mathematics Institute, The University of Warwick, Coventry, United Kingdom.; The School of Life Sciences, The University of Warwick, Coventry, United Kingdom.
Rock KS; Zeeman Institute for System Biology and Infectious Disease Epidemiology Research, The University of Warwick, Coventry, United Kingdom.; Mathematics Institute, The University of Warwick, Coventry, United Kingdom.
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Źródło :
PLoS computational biology [PLoS Comput Biol] 2021 Jan 29; Vol. 17 (1), pp. e1008532. Date of Electronic Publication: 2021 Jan 29 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Models, Statistical*
Trypanosoma brucei gambiense*
Trypanosomiasis, African*/epidemiology
Trypanosomiasis, African*/parasitology
Trypanosomiasis, African*/transmission
Bayes Theorem ; Computational Biology ; Democratic Republic of the Congo/epidemiology ; Humans ; Models, Biological
Czasopismo naukowe
Tytuł :
Analytical sensitivity of loopamp and quantitative real-time PCR on dried blood spots and their potential role in monitoring human African trypanosomiasis elimination.
Autorzy :
Alfred Compaoré CF; Centre International of Recherche-Développement sur l'Élevage en Zone Subhumide, Unité de Recherche sur les Maladies à Vecteurs et Biodiversité, 01 BP 454, Bobo-Dioulasso 01, Burkina Faso; Université Nazi Boni, Unité de Formation et de Recherche Sciences et Techniques, 01 BP 1091, Bobo-Dioulasso, Burkina Faso.
Ilboudo H; Institut de Recherche en Sciences de la Santé, Unité de Recherche Clinique de Nanoro, 11 BP 218, Ouagadougou CMS 11, Burkina Faso.
Kaboré J; Centre International of Recherche-Développement sur l'Élevage en Zone Subhumide, Unité de Recherche sur les Maladies à Vecteurs et Biodiversité, 01 BP 454, Bobo-Dioulasso 01, Burkina Faso; Université Nazi Boni, Unité de Formation et de Recherche Sciences et Techniques, 01 BP 1091, Bobo-Dioulasso, Burkina Faso.
Kaboré JW; Centre International of Recherche-Développement sur l'Élevage en Zone Subhumide, Unité de Recherche sur les Maladies à Vecteurs et Biodiversité, 01 BP 454, Bobo-Dioulasso 01, Burkina Faso; Programme National de Lutte Contre la Trypanosomiase Humaine Africaine, BP 581, Conakry, Guinea.
Camara O; Programme National de Lutte Contre la Trypanosomiase Humaine Africaine, BP 581, Conakry, Guinea.
Bamba M; Centre International of Recherche-Développement sur l'Élevage en Zone Subhumide, Unité de Recherche sur les Maladies à Vecteurs et Biodiversité, 01 BP 454, Bobo-Dioulasso 01, Burkina Faso.
Sakande H; Centre International of Recherche-Développement sur l'Élevage en Zone Subhumide, Unité de Recherche sur les Maladies à Vecteurs et Biodiversité, 01 BP 454, Bobo-Dioulasso 01, Burkina Faso.
Koné M; Institut Pierre Richet, Unité de Recherche « Trypanosomoses », 01 BP 1500, Bouake, West Africa.
Camara M; Programme National de Lutte Contre la Trypanosomiase Humaine Africaine, BP 581, Conakry, Guinea.
Kaba D; Institut Pierre Richet, Unité de Recherche « Trypanosomoses », 01 BP 1500, Bouake, West Africa.
Gaston Belem AM; Université Nazi Boni, Unité de Formation et de Recherche Sciences et Techniques, 01 BP 1091, Bobo-Dioulasso, Burkina Faso.
Deborggraeve S; Institute of Tropical Medicine, Department of Biomedical Sciences, Nationalestraat 155, B-2000 Antwerp, Belgium.
Büscher P; Institute of Tropical Medicine, Department of Biomedical Sciences, Nationalestraat 155, B-2000 Antwerp, Belgium.
Bucheton B; Programme National de Lutte Contre la Trypanosomiase Humaine Africaine, BP 581, Conakry, Guinea; Institut de Recherche pour le Développement, UMR INTERTRYP IRD-CIRAD, Université de Montpellier, TA A-17/G, Campus International de Baillarguet, F-34398, Montpellier, France.
Lejon V; Institut de Recherche pour le Développement, UMR INTERTRYP IRD-CIRAD, Université de Montpellier, TA A-17/G, Campus International de Baillarguet, F-34398, Montpellier, France.
Jamonneau V; Institut Pierre Richet, Unité de Recherche « Trypanosomoses », 01 BP 1500, Bouake, West Africa; Institut de Recherche pour le Développement, UMR INTERTRYP IRD-CIRAD, Université de Montpellier, TA A-17/G, Campus International de Baillarguet, F-34398, Montpellier, France. Electronic address: .
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Źródło :
Experimental parasitology [Exp Parasitol] 2020 Dec; Vol. 219, pp. 108014. Date of Electronic Publication: 2020 Oct 02.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Molecular Diagnostic Techniques/*standards
Nucleic Acid Amplification Techniques/*standards
Real-Time Polymerase Chain Reaction/*standards
Trypanosoma brucei gambiense/*isolation & purification
Trypanosomiasis, African/*prevention & control
Algorithms ; Animals ; Blood Specimen Collection/methods ; Blood Specimen Collection/standards ; DNA, Protozoan/isolation & purification ; High-Throughput Screening Assays/methods ; High-Throughput Screening Assays/standards ; Humans ; Mice ; Real-Time Polymerase Chain Reaction/methods ; Sensitivity and Specificity ; Specimen Handling/methods ; Specimen Handling/standards ; Trypanosoma brucei gambiense/genetics ; Trypanosomiasis, African/blood ; Trypanosomiasis, African/diagnosis
SCR Protocol :
LAMP assay
Czasopismo naukowe
Tytuł :
Development and implementation of a strategy for intensified screening for gambiense human African trypanosomiasis in Kongo Central province, DRC.
Autorzy :
Lumbala C; Directorate of Disease Control, Ministry of Public Health, Democratic Republic of the Congo.; Global Health Institute, Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium.
Kayembe S; Foundation for Innovative New Diagnostics (FIND), Geneva, Switzerland.
Makabuza J; Programme National de Lutte Contre la Trypanosomiase Humaine Africaine, Kinshasa, République Démocratique du Congo.
Lutumba P; Kinshasa University, Kinshasa, Democratic Republic of the Congo.
Van Geertruyden JP; Global Health Institute, Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium.
Bessell PR; Epi Interventions, Edinburgh, United Kingdom.
Ndung'u JM; Foundation for Innovative New Diagnostics (FIND), Geneva, Switzerland.
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Źródło :
PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2020 Oct 15; Vol. 14 (10), pp. e0008779. Date of Electronic Publication: 2020 Oct 15 (Print Publication: 2020).
Typ publikacji :
Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Mass Screening/*methods
Trypanosoma brucei gambiense/*isolation & purification
Trypanosomiasis, African/*diagnosis
Animals ; Democratic Republic of the Congo/epidemiology ; Diagnostic Tests, Routine ; Humans ; Molecular Diagnostic Techniques ; Nucleic Acid Amplification Techniques ; Trypanosoma brucei gambiense/classification ; Trypanosoma brucei gambiense/genetics ; Trypanosomiasis, African/epidemiology ; Trypanosomiasis, African/parasitology
SCR Protocol :
LAMP assay
Czasopismo naukowe
Tytuł :
A pilot study demonstrating the identification of Trypanosoma brucei gambiense and T. b. rhodesiense in vectors using a multiplexed high-resolution melt qPCR.
Autorzy :
Garrod G; Department of Vector Biology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
Adams ER; Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
Lingley JK; Department of Vector Biology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
Saldanha I; Department of Vector Biology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
Torr SJ; Department of Vector Biology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
Cunningham LJ; Department of Vector Biology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
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Źródło :
PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2020 Nov 25; Vol. 14 (11), pp. e0008308. Date of Electronic Publication: 2020 Nov 25 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA, Protozoan/*analysis
Trypanosoma brucei gambiense/*genetics
Trypanosoma brucei rhodesiense/*genetics
Trypanosomiasis, African/*diagnosis
Tsetse Flies/*parasitology
Animals ; DNA Primers/genetics ; DNA, Protozoan/genetics ; Humans ; Limit of Detection ; Mass Screening/methods ; Nucleic Acid Denaturation/genetics ; Proof of Concept Study ; Real-Time Polymerase Chain Reaction ; Trypanosoma brucei gambiense/isolation & purification ; Trypanosoma brucei rhodesiense/isolation & purification
Czasopismo naukowe
Tytuł :
Trypa-NO! contributes to the elimination of gambiense human African trypanosomiasis by combining tsetse control with "screen, diagnose and treat" using innovative tools and strategies.
Autorzy :
Ndung'u JM; Foundation for Innovative New Diagnostics (FIND), Geneva, Switzerland.
Boulangé A; Centre International de Recherche-Développement sur l'Elevage en zone Subhumide (CIRDES), Bobo Dioulasso, Burkina Faso.; Centre International de Recherche Agronomique pour le Développement (CIRAD), UMR INTERTRYP, Montpellier, France.
Picado A; Foundation for Innovative New Diagnostics (FIND), Geneva, Switzerland.
Mugenyi A; Coordinating Office for Control of Trypanosomiasis in Uganda (COCTU), Entebbe, Uganda.
Mortensen A; Vestergaard SA, Lausanne, Switzerland.
Hope A; Liverpool School of Tropical Medicine (LSTM), Liverpool, United Kingdom.
Mollo BG; Institut de Recherche en Elevage pour le Développement (IRED), N'Djamena, Chad.
Bucheton B; Institut de Recherche pour le Développement (IRD), INTERTRYP, CIRAD, Université Montpellier, Montpellier, France.; Programme National de Lutte contre la Trypanosomiase Humaine Africaine, Conakry, Guinea.
Wamboga C; Ministry of Health (MOH), Kampala, Uganda.
Waiswa C; Coordinating Office for Control of Trypanosomiasis in Uganda (COCTU), Entebbe, Uganda.
Kaba D; Institut Pierre Richet/Institut National de Santé Publique (IPR/INSP), Bouaké, Côte d'Ivoire.
Matovu E; College of Veterinary Medicine, Animal Resources and Biosecurity (COVAB), Makerere University, Kampala, Uganda.
Courtin F; Institut de Recherche pour le Développement (IRD), INTERTRYP, CIRAD, Université Montpellier, Montpellier, France.; Institut Pierre Richet/Institut National de Santé Publique (IPR/INSP), Bouaké, Côte d'Ivoire.
Garrod G; Liverpool School of Tropical Medicine (LSTM), Liverpool, United Kingdom.
Gimonneau G; Centre International de Recherche-Développement sur l'Elevage en zone Subhumide (CIRDES), Bobo Dioulasso, Burkina Faso.; Centre International de Recherche Agronomique pour le Développement (CIRAD), UMR INTERTRYP, Montpellier, France.
Bingham GV; Vestergaard SA, Lausanne, Switzerland.
Hassane HM; Institut de Recherche en Elevage pour le Développement (IRED), N'Djamena, Chad.
Tirados I; Liverpool School of Tropical Medicine (LSTM), Liverpool, United Kingdom.
Saldanha I; Liverpool School of Tropical Medicine (LSTM), Liverpool, United Kingdom.
Kabore J; Centre International de Recherche-Développement sur l'Elevage en zone Subhumide (CIRDES), Bobo Dioulasso, Burkina Faso.
Rayaisse JB; Centre International de Recherche-Développement sur l'Elevage en zone Subhumide (CIRDES), Bobo Dioulasso, Burkina Faso.
Bart JM; Institut de Recherche pour le Développement (IRD), INTERTRYP, CIRAD, Université Montpellier, Montpellier, France.
Lingley J; Liverpool School of Tropical Medicine (LSTM), Liverpool, United Kingdom.
Esterhuizen J; Liverpool School of Tropical Medicine (LSTM), Liverpool, United Kingdom.
Longbottom J; Liverpool School of Tropical Medicine (LSTM), Liverpool, United Kingdom.
Pulford J; Liverpool School of Tropical Medicine (LSTM), Liverpool, United Kingdom.
Kouakou L; Programme National d'Elimination de la THA (PNETHA), Abidjan, Côte d'Ivoire.
Sanogo L; Centre International de Recherche-Développement sur l'Elevage en zone Subhumide (CIRDES), Bobo Dioulasso, Burkina Faso.
Cunningham L; Liverpool School of Tropical Medicine (LSTM), Liverpool, United Kingdom.
Camara M; Institut de Recherche pour le Développement (IRD), INTERTRYP, CIRAD, Université Montpellier, Montpellier, France.
Koffi M; Université Jean Lorougnon Guédé (UJLoG), Daloa, Côte d'Ivoire.
Stanton M; Liverpool School of Tropical Medicine (LSTM), Liverpool, United Kingdom.
Lehane M; Liverpool School of Tropical Medicine (LSTM), Liverpool, United Kingdom.
Kagbadouno MS; Programme National de Lutte contre la Trypanosomiase Humaine Africaine, Conakry, Guinea.
Camara O; Programme National de Lutte contre la Trypanosomiase Humaine Africaine, Conakry, Guinea.
Bessell P; Epi Interventions, Edinburgh, United Kingdom.
Mallaye P; Programme National de Lutte contre la Trypanosomiase Humaine Africaine (PNLTHA), Chad.
Solano P; Institut de Recherche pour le Développement (IRD), INTERTRYP, CIRAD, Université Montpellier, Montpellier, France.
Selby R; Liverpool School of Tropical Medicine (LSTM), Liverpool, United Kingdom.
Dunkley S; Liverpool School of Tropical Medicine (LSTM), Liverpool, United Kingdom.
Torr S; Liverpool School of Tropical Medicine (LSTM), Liverpool, United Kingdom.
Biéler S; Foundation for Innovative New Diagnostics (FIND), Geneva, Switzerland.
Lejon V; Institut de Recherche pour le Développement (IRD), INTERTRYP, CIRAD, Université Montpellier, Montpellier, France.
Jamonneau V; Institut de Recherche pour le Développement (IRD), INTERTRYP, CIRAD, Université Montpellier, Montpellier, France.; Ministry of Health (MOH), Kampala, Uganda.
Yoni W; Centre International de Recherche-Développement sur l'Elevage en zone Subhumide (CIRDES), Bobo Dioulasso, Burkina Faso.
Katz Z; Foundation for Innovative New Diagnostics (FIND), Geneva, Switzerland.
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Źródło :
PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2020 Nov 12; Vol. 14 (11), pp. e0008738. Date of Electronic Publication: 2020 Nov 12 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
International Cooperation*
Trypanosomiasis, African*/diagnosis
Trypanosomiasis, African*/drug therapy
Trypanosomiasis, African*/prevention & control
Mass Screening/*methods
Trypanosoma brucei gambiense/*drug effects
Trypanosoma brucei rhodesiense/*drug effects
Animals ; Antibodies, Protozoan/blood ; Chad ; Cote d'Ivoire ; Disease Vectors ; Guinea ; Humans ; Insect Control/methods ; Insecticides/administration & dosage ; Trypanosoma brucei gambiense/isolation & purification ; Trypanosoma brucei rhodesiense/isolation & purification ; Tsetse Flies/parasitology ; Uganda
Czasopismo naukowe
Tytuł :
Development of a bio-inkjet printed LAMP test kit for detecting human African trypanosomiasis.
Autorzy :
Hayashida K; Division of Collaboration and Education, Research Center for Zoonosis Control (CZC), Hokkaido University, Sapporo, Japan.; International Collaboration Unit, Research Center for Zoonosis Control, Hokkaido University, Sapporo, Japan.
Nambala P; Department of Pathology, College of Medicine, University of Malawi, Blantyre, Malawi.
Reet NV; Department of Biomedical Sciences, Institute of Tropical Medicine, Antwerpen, Belgium.
Büscher P; Department of Biomedical Sciences, Institute of Tropical Medicine, Antwerpen, Belgium.
Kawai N; Division of Collaboration and Education, Research Center for Zoonosis Control (CZC), Hokkaido University, Sapporo, Japan.
Mutengo MM; Institute of Basic and Biomedical Sciences, Levy Mwanawasa Medical University, Lusaka, Zambia.
Musaya J; Department of Pathology, College of Medicine, University of Malawi, Blantyre, Malawi.
Namangala B; Department of Paraclinical Studies, School of Veterinary Medicine, University of Zambia, Lusaka, Zambia.
Sugimoto C; Division of Collaboration and Education, Research Center for Zoonosis Control (CZC), Hokkaido University, Sapporo, Japan.
Yamagishi J; Division of Collaboration and Education, Research Center for Zoonosis Control (CZC), Hokkaido University, Sapporo, Japan.; International Collaboration Unit, Research Center for Zoonosis Control, Hokkaido University, Sapporo, Japan.
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Źródło :
PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2020 Oct 22; Vol. 14 (10), pp. e0008753. Date of Electronic Publication: 2020 Oct 22 (Print Publication: 2020).
Typ publikacji :
Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Molecular Diagnostic Techniques/*methods
Nucleic Acid Amplification Techniques/*methods
Trypanosoma brucei gambiense/*isolation & purification
Trypanosoma brucei rhodesiense/*isolation & purification
Trypanosomiasis, African/*diagnosis
Animals ; DNA, Protozoan/analysis ; Humans ; Malawi ; Point-of-Care Systems ; Sensitivity and Specificity ; Trypanosoma brucei gambiense/genetics ; Trypanosoma brucei rhodesiense/genetics
SCR Protocol :
LAMP assay
Czasopismo naukowe
Tytuł :
Screening Strategies for a Sustainable Endpoint for Gambiense Sleeping Sickness.
Autorzy :
Castaño MS; Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland.; University of Basel, Basel, Switzerland.
Aliee M; Mathematics Institute, University of Warwick, Coventry, United Kingdom.; Zeeman Institute for Systems Biology and Infectious Disease Epidemiology Research (SBIDER), University of Warwick, Coventry, United Kingdom.
Mwamba Miaka E; Programme National de Lutte contre la Trypanosomiase Humaine Africaine, Kinshasa, the Democratic Republic of the Congo.
Keeling MJ; Mathematics Institute, University of Warwick, Coventry, United Kingdom.; Zeeman Institute for Systems Biology and Infectious Disease Epidemiology Research (SBIDER), University of Warwick, Coventry, United Kingdom.; School of Life Science, University of Warwick, Coventry, United Kingdom.
Chitnis N; Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland.; University of Basel, Basel, Switzerland.
Rock KS; Mathematics Institute, University of Warwick, Coventry, United Kingdom.; Zeeman Institute for Systems Biology and Infectious Disease Epidemiology Research (SBIDER), University of Warwick, Coventry, United Kingdom.
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Źródło :
The Journal of infectious diseases [J Infect Dis] 2020 Jun 11; Vol. 221 (Suppl 5), pp. S539-S545.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Trypanosoma brucei gambiense*
Trypanosomiasis, African/*diagnosis
Trypanosomiasis, African/*epidemiology
Democratic Republic of the Congo/epidemiology ; Disease Eradication ; Humans ; Models, Biological ; Stochastic Processes ; Trypanosomiasis, African/prevention & control
Czasopismo naukowe
Tytuł :
Evidence of the absence of human African trypanosomiasis in two northern districts of Uganda: Analyses of cattle, pigs and tsetse flies for the presence of Trypanosoma brucei gambiense.
Autorzy :
Cunningham LJ; Department of Vector Biology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
Lingley JK; Department of Vector Biology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
Tirados I; Department of Vector Biology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
Esterhuizen J; Department of Vector Biology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
Opiyo M; Institute for Global Health, University of Barcelona, Barcelona, Spain.; Centro de Investigação em Saúde de Manhiça (CISM), Maputo, Mozambique.
Mangwiro CTN; Department of Animal Science, Bindura University of Science Education, Bindura, Zimbabwe.
Lehane MJ; Department of Vector Biology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
Torr SJ; Department of Vector Biology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
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Źródło :
PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2020 Apr 07; Vol. 14 (4), pp. e0007737. Date of Electronic Publication: 2020 Apr 07 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Topography, Medical*
Animals, Domestic/*parasitology
Disease Reservoirs/*parasitology
Trypanosoma brucei gambiense/*isolation & purification
Trypanosomiasis, African/*epidemiology
Trypanosomiasis, African/*veterinary
Tsetse Flies/*parasitology
Animals ; Blood/parasitology ; Cattle ; Humans ; Microscopy ; Polymerase Chain Reaction ; Prevalence ; Swine ; Trypanosoma brucei gambiense/genetics ; Uganda/epidemiology
Czasopismo naukowe
Tytuł :
Molecular identification of Trypanosoma brucei gambiense in naturally infected pigs, dogs and small ruminants confirms domestic animals as potential reservoirs for sleeping sickness in Chad.
Autorzy :
Vourchakbé J
Tiofack ZAA; Molecular Parasitology and Entomology Unit, Department of Biochemistry, Faculty of Science, University of Dschang, PO Box 67 Dschang, Cameroon.
Kante TS; Molecular Parasitology and Entomology Unit, Department of Biochemistry, Faculty of Science, University of Dschang, PO Box 67 Dschang, Cameroon.
Mpoame M; Laboratory of Applied Biology and Ecology (LABEA), Department of Animal Biology, Faculty of Science, University of Dschang, PO Box 067 Dschang, Cameroon.
Simo G; Molecular Parasitology and Entomology Unit, Department of Biochemistry, Faculty of Science, University of Dschang, PO Box 67 Dschang, Cameroon.
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Transliterated Title :
L’identification moléculaire de Trypanosoma brucei gambiense chez les porcs, les chiens et les petits ruminants naturellement infectés confirme les animaux domestiques comme réservoirs potentiels de la maladie du sommeil au Tchad.
Źródło :
Parasite (Paris, France) [Parasite] 2020; Vol. 27, pp. 63. Date of Electronic Publication: 2020 Nov 18.
Typ publikacji :
Journal Article
MeSH Terms :
Animals, Domestic*/parasitology
Disease Reservoirs*
Trypanosoma brucei gambiense*/genetics
Trypanosomiasis, African*/epidemiology
Trypanosomiasis, African*/parasitology
Trypanosomiasis, African*/veterinary
Animals ; Chad/epidemiology ; Dogs/parasitology ; Goats/parasitology ; Sheep/parasitology ; Swine/parasitology
Czasopismo naukowe
Tytuł :
Blood signatures for second stage human African trypanosomiasis: a transcriptomic approach.
Autorzy :
Mulindwa J; Department of Biochemistry and Sports Sciences, College of Natural Sciences, Makerere University, P. O. Box 7062, Kampala, Uganda. .
Matovu E; Department of Biotechnical and Diagnostic Sciences, College of Veterinary Medicine, Animal Resources and Biosecurity, Makerere University, P. O. Box 7062, Kampala, Uganda.
Enyaru J; Department of Biochemistry and Sports Sciences, College of Natural Sciences, Makerere University, P. O. Box 7062, Kampala, Uganda.
Clayton C; Centre for Molecular Biology of Heidelberg University (ZMBH), DKFZ-ZMBH Alliance, Im Neuenheimer Feld 282, 69120, Heidelberg, Germany.
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Źródło :
BMC medical genomics [BMC Med Genomics] 2020 Jan 30; Vol. 13 (1), pp. 14. Date of Electronic Publication: 2020 Jan 30.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
RNA-Seq*
Transcriptome*
Trypanosoma brucei gambiense*
Trypanosomiasis, African*/blood
Trypanosomiasis, African*/cerebrospinal fluid
Up-Regulation*
Adolescent ; Adult ; Biomarkers/blood ; Biomarkers/cerebrospinal fluid ; Child ; Female ; Humans ; Male
Czasopismo naukowe
Tytuł :
Prescription of concomitant medications in patients treated with Nifurtimox Eflornithine Combination Therapy (NECT) for T.b. gambiense second stage sleeping sickness in the Democratic Republic of the Congo.
Autorzy :
Kuemmerle A; Swiss Tropical and Public Health Institute, Basel, Switzerland.; University of Basel, Basel, Switzerland.
Schmid C; Swiss Tropical and Public Health Institute, Basel, Switzerland.; University of Basel, Basel, Switzerland.
Kande V; Programme National de Lutte contre la Trypanosomiase Humaine Africaine, Democratic Republic of the Congo.
Mutombo W; Programme National de Lutte contre la Trypanosomiase Humaine Africaine, Democratic Republic of the Congo.; DNDi, Geneva, Switzerland.
Ilunga M; Programme National de Lutte contre la Trypanosomiase Humaine Africaine, Democratic Republic of the Congo.
Lumpungu I; Programme National de Lutte contre la Trypanosomiase Humaine Africaine, Democratic Republic of the Congo.
Mutanda S; Programme National de Lutte contre la Trypanosomiase Humaine Africaine, Democratic Republic of the Congo.
Nganzobo P; Programme National de Lutte contre la Trypanosomiase Humaine Africaine, Democratic Republic of the Congo.
Ngolo D; Programme National de Lutte contre la Trypanosomiase Humaine Africaine, Democratic Republic of the Congo.; DNDi, Geneva, Switzerland.
Kisala M; Bureau Diocesain d'Oeuvres Medicales, Kikwit, Democratic Republic of the Congo.
Valverde Mordt O; DNDi, Geneva, Switzerland.
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Źródło :
PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2020 Jan 27; Vol. 14 (1), pp. e0008028. Date of Electronic Publication: 2020 Jan 27 (Print Publication: 2020).
Typ publikacji :
Clinical Trial; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
MeSH Terms :
Trypanosoma brucei gambiense*
Eflornithine/*therapeutic use
Nifurtimox/*therapeutic use
Trypanocidal Agents/*therapeutic use
Trypanosomiasis, African/*drug therapy
Democratic Republic of the Congo/epidemiology ; Drug Therapy, Combination ; Eflornithine/administration & dosage ; Humans ; Nifurtimox/administration & dosage ; Treatment Outcome ; Trypanosomiasis, African/epidemiology
Czasopismo naukowe
Tytuł :
Establishment of a Standardized Vaccine Protocol for the Analysis of Protective Immune Responses During Experimental Trypanosome Infections in Mice.
Autorzy :
Radwanska M; Biomedical Research Centre, Department of Environmental Technology, Food Technology and Molecular Biotechnology, Ghent University, Incheon, South Korea.; Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium.
Nguyen HTT; Biomedical Research Centre, Department of Environmental Technology, Food Technology and Molecular Biotechnology, Ghent University, Incheon, South Korea.; Department of Biochemistry and Microbiology, Ghent University, Ghent, Belgium.; Laboratory of Cellular and Molecular Immunology, Vrije Universiteit Brussel, Brussels, Belgium.
Moon S; Biomedical Research Centre, Department of Environmental Technology, Food Technology and Molecular Biotechnology, Ghent University, Incheon, South Korea.; Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium.; Laboratory of Cellular and Molecular Immunology, Vrije Universiteit Brussel, Brussels, Belgium.
Obishakin E; Biomedical Research Centre, Department of Environmental Technology, Food Technology and Molecular Biotechnology, Ghent University, Incheon, South Korea.; Biotechnology Division, National Veterinary Research Institute, Vom, Plateau, Nigeria.
Magez S; Biomedical Research Centre, Department of Environmental Technology, Food Technology and Molecular Biotechnology, Ghent University, Incheon, South Korea. .; Department of Biochemistry and Microbiology, Ghent University, Ghent, Belgium. .; Laboratory of Cellular and Molecular Immunology, Vrije Universiteit Brussel, Brussels, Belgium. .
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Źródło :
Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2020; Vol. 2116, pp. 721-738.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Protozoan Vaccines/*administration & dosage
Research Design/*standards
Trypanosoma brucei gambiense/*immunology
Trypanosomiasis, African/*veterinary
Vaccination/*methods
Animals ; Disease Models, Animal ; Livestock/parasitology ; Mice ; Protozoan Vaccines/immunology ; Trypanosoma brucei gambiense/isolation & purification ; Trypanosomiasis, African/immunology ; Trypanosomiasis, African/parasitology ; Trypanosomiasis, African/prevention & control
Czasopismo naukowe
Tytuł :
Unusual MRI Findings in African Trypanosoma brucei gambiense Trypanosomiasis: Dentate Nuclei and Hypothalamic Lesions.
Autorzy :
Boukobza M; Department of Radiology, Assistance Publique-Hôpitaux de Paris, Bichat University Hospital, Paris, France.
Lariven S; Infectious and Tropical Diseases Department, Assistance Publique-Hôpitaux de Paris, Bichat-Claude Bernard University Hospital, Paris, France.
Houzé S; Parasitology and Mycology Laboratory, Assistance Publique-Hôpitaux de Paris, Bichat-Claude Bernard University Hospital, Paris, France.
Laissy JP; University Paris 7, Bichat Hospital, Paris, France.; INSERM U1148, Paris, France.; Department of Radiology, Assistance Publique-Hôpitaux de Paris, Bichat University Hospital, Paris, France.
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Źródło :
The American journal of tropical medicine and hygiene [Am J Trop Med Hyg] 2020 Jan; Vol. 102 (1), pp. 5-6.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Magnetic Resonance Imaging*
Trypanosoma brucei gambiense*
Cerebellar Nuclei/*pathology
Hypothalamus/*pathology
Trypanosomiasis, African/*pathology
Cerebellar Nuclei/parasitology ; Drug Therapy, Combination ; Eflornithine/administration & dosage ; Eflornithine/therapeutic use ; Humans ; Hypothalamus/parasitology ; Male ; Middle Aged ; Nifurtimox/administration & dosage ; Nifurtimox/therapeutic use ; Trypanocidal Agents/administration & dosage ; Trypanocidal Agents/therapeutic use ; Trypanosomiasis, African/drug therapy ; Trypanosomiasis, African/parasitology
Czasopismo naukowe
Tytuł :
Trypanosoma brucei gambiense Group 2: The Unusual Suspect.
Autorzy :
Jamonneau V; INTERTRYP, IRD, Cirad, Univ Montpellier, Montpellier, France. Electronic address: .
Truc P; INTERTRYP, IRD, Cirad, Univ Montpellier, Montpellier, France.
Grébaut P; INTERTRYP, IRD, Cirad, Univ Montpellier, Montpellier, France.
Herder S; INTERTRYP, IRD, Cirad, Univ Montpellier, Montpellier, France.
Ravel S; INTERTRYP, IRD, Cirad, Univ Montpellier, Montpellier, France.
Solano P; INTERTRYP, IRD, Cirad, Univ Montpellier, Montpellier, France.
De Meeus T; INTERTRYP, IRD, Cirad, Univ Montpellier, Montpellier, France.
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Źródło :
Trends in parasitology [Trends Parasitol] 2019 Dec; Vol. 35 (12), pp. 983-995. Date of Electronic Publication: 2019 Oct 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Trypanosoma brucei gambiense/*classification
Trypanosomiasis, African/*parasitology
Africa, Western/epidemiology ; Animals ; Demography ; Genetic Markers/genetics ; Humans ; Trypanosoma brucei gambiense/genetics ; Trypanosomiasis, African/epidemiology
Czasopismo naukowe
Tytuł :
Six New Phenylpropanoid Derivatives from Chemically Converted Extract of Alpinia galanga (L.) and Their Antiparasitic Activities.
Autorzy :
Sulistyowaty MI; Graduate School of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8553, Japan.; Faculty of Pharmacy, Universitas Airlangga, Surabaya 60286, Indonesia.
Uyen NH; Graduate School of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8553, Japan.
Suganuma K; National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Inada, Obihiro 080-8555, Hokkaido, Japan.
Chitama BA; Department of Protozoology, Institute of Tropical Medicine (NEKKEN), Nagasaki University, 1-12-4 Sakamoto, Nagasaki 852-8523, Japan.
Yahata K; Department of Protozoology, Institute of Tropical Medicine (NEKKEN), Nagasaki University, 1-12-4 Sakamoto, Nagasaki 852-8523, Japan.
Kaneko O; Department of Protozoology, Institute of Tropical Medicine (NEKKEN), Nagasaki University, 1-12-4 Sakamoto, Nagasaki 852-8523, Japan.
Sugimoto S; Graduate School of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8553, Japan.
Yamano Y; Graduate School of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8553, Japan.
Kawakami S; Department of Natural Products Chemistry, Faculty of Pharmacy, Yasuda Women's University, 6-13-1 Yasuhigashi, Asaminami-ku, Hiroshima 731-0153, Japan.
Otsuka H; Department of Natural Products Chemistry, Faculty of Pharmacy, Yasuda Women's University, 6-13-1 Yasuhigashi, Asaminami-ku, Hiroshima 731-0153, Japan.
Matsunami K; Graduate School of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8553, Japan.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Mar 21; Vol. 26 (6). Date of Electronic Publication: 2021 Mar 21.
Typ publikacji :
Journal Article
MeSH Terms :
Antimalarials*/chemistry
Antimalarials*/isolation & purification
Antimalarials*/pharmacology
Propanols*/chemistry
Propanols*/isolation & purification
Propanols*/pharmacology
Alpinia/*chemistry
Plant Extracts/*chemistry
Plasmodium falciparum/*growth & development
Trypanosoma brucei gambiense/*growth & development
Trypanosoma brucei rhodesiense/*growth & development
Trypanocidal Agents/chemistry ; Trypanocidal Agents/isolation & purification ; Trypanocidal Agents/pharmacology
Czasopismo naukowe
Tytuł :
Predicting the impact of COVID-19 interruptions on transmission of gambiense human African trypanosomiasis in two health zones of the Democratic Republic of Congo.
Autorzy :
Aliee M; Zeeman Institute (SBIDER), University of Warwick, Mathematical Sciences Building, Gibbet Hill Road, Coventry, CV4 7AL, UK.
Castaño S; Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Socinstrasse 57, Postfach, CH-4002 Basel, Switzerland.
Davis CN; Zeeman Institute (SBIDER), University of Warwick, Mathematical Sciences Building, Gibbet Hill Road, Coventry, CV4 7AL, UK.
Patel S; Department of Statistics, University of Warwick, Mathematical Sciences Building, Gibbet Hill Road, Coventry, CV4 7AL, UK.
Miaka EM; Programme National de lutte contre la THA (PNLTHA), Kinshasa 2, Democratic Republic of the Congo.
Spencer SEF; Department of Statistics, University of Warwick, Mathematical Sciences Building, Gibbet Hill Road, Coventry, CV4 7AL, UK.
Keeling MJ; Zeeman Institute (SBIDER), University of Warwick, Mathematical Sciences Building, Gibbet Hill Road, Coventry, CV4 7AL, UK.
Chitnis N; Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Socinstrasse 57, Postfach, CH-4002 Basel, Switzerland.
Rock KS; Zeeman Institute (SBIDER), University of Warwick, Mathematical Sciences Building, Gibbet Hill Road, Coventry, CV4 7AL, UK.
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Źródło :
Transactions of the Royal Society of Tropical Medicine and Hygiene [Trans R Soc Trop Med Hyg] 2021 Mar 06; Vol. 115 (3), pp. 245-252.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
COVID-19/*epidemiology
Communicable Disease Control/*organization & administration
Trypanosomiasis, African/*epidemiology
Trypanosomiasis, African/*prevention & control
Democratic Republic of the Congo/epidemiology ; Humans ; Models, Theoretical ; Neglected Diseases/epidemiology ; Neglected Diseases/prevention & control ; Pandemics ; Population Surveillance ; SARS-CoV-2 ; Trypanosoma brucei gambiense
Czasopismo naukowe
Tytuł :
Accelerating elimination of sleeping sickness from the Guinean littoral through enhanced screening in the post-Ebola context: A retrospective analysis.
Autorzy :
Camara O; Programme National de Lutte contre la Trypanosomiase Humaine Africaine, Conakry, Guinea.
Biéler S; Foundation for Innovative New Diagnostics (FIND), Geneva, Switzerland.
Bucheton B; Institut de Recherche pour le Développement (IRD), INTERTRYP, CIRAD, Université de Montpellier, Montpellier, France.
Kagbadouno M; Programme National de Lutte contre la Trypanosomiase Humaine Africaine, Conakry, Guinea.
Mathu Ndung'u J; Foundation for Innovative New Diagnostics (FIND), Geneva, Switzerland.
Solano P; Institut de Recherche pour le Développement (IRD), INTERTRYP, CIRAD, Université de Montpellier, Montpellier, France.
Camara M; Programme National de Lutte contre la Trypanosomiase Humaine Africaine, Conakry, Guinea.
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Źródło :
PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2021 Feb 16; Vol. 15 (2), pp. e0009163. Date of Electronic Publication: 2021 Feb 16 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Mass Screening/*statistics & numerical data
Trypanosomiasis, African/*diagnosis
Trypanosomiasis, African/*epidemiology
Diagnostic Tests, Routine/statistics & numerical data ; Guinea/epidemiology ; Hemorrhagic Fever, Ebola ; Humans ; Prevalence ; Retrospective Studies ; Trypanosoma brucei gambiense/isolation & purification
Czasopismo naukowe
Tytuł :
Cerebrospinal Fluid-Derived Microvesicles From Sleeping Sickness Patients Alter Protein Expression in Human Astrocytes.
Autorzy :
Dozio V; Translational Biomarker Group, University of Geneva, Geneva, Switzerland.
Lejon V; Intertryp, Institut de Recherche pour le Développement, CIRAD, University of Montpellier, Montpellier, France.
Mumba Ngoyi D; Department of Parasitology, Institut National de Recherche Biomédicale, Kinshasa, Democratic Republic of Congo.
Büscher P; Department of Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.
Sanchez JC; Translational Biomarker Group, University of Geneva, Geneva, Switzerland.
Tiberti N; Translational Biomarker Group, University of Geneva, Geneva, Switzerland.; Department of Infectious - Tropical Diseases and Microbiology, IRCCS Sacro Cuore Don Calabria Hospital, Verona, Italy.
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Źródło :
Frontiers in cellular and infection microbiology [Front Cell Infect Microbiol] 2019 Nov 20; Vol. 9, pp. 391. Date of Electronic Publication: 2019 Nov 20 (Print Publication: 2019).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Trypanosoma brucei gambiense*
Astrocytes/*metabolism
Extracellular Vesicles/*metabolism
Trypanosomiasis, African/*metabolism
Biomarkers ; Congo ; Extracellular Vesicles/ultrastructure ; Female ; Flow Cytometry ; Host-Parasite Interactions ; Humans ; Male ; Neglected Diseases ; Proteome ; Proteomics ; Trypanosomiasis, African/cerebrospinal fluid ; Trypanosomiasis, African/diagnosis ; Trypanosomiasis, African/parasitology
Czasopismo naukowe
Tytuł :
Trypanosoma brucei gambiense excreted/secreted factors impair lipopolysaccharide-induced maturation and activation of human monocyte-derived dendritic cells.
Autorzy :
Dauchy FA; Laboratoire de Parasitologie, UMR IRD CIRAD INTERTRYP 177, University of Bordeaux, Bordeaux, France.; UMR INTERTRYP 177, IRD-CIRAD-University of Bordeaux, Montpellier, France.; Department of Infectious and Tropical Diseases, Hôpital Pellegrin, CHU de Bordeaux, Bordeaux, France.
Contin-Bordes C; Laboratoire d'Immunologie et d'Immunogénétique, CHU de Bordeaux, Bordeaux, France.; UMR 5164 CIRID, University of Bordeaux, Bordeaux, France.
Nzoumbou-Boko R; Laboratoire de Parasitologie, UMR IRD CIRAD INTERTRYP 177, University of Bordeaux, Bordeaux, France.; UMR INTERTRYP 177, IRD-CIRAD-University of Bordeaux, Montpellier, France.
Bonhivers M; Microbiologie Fondamentale et Pathogénicité, UMR 5234, University of Bordeaux, Bordeaux, France.; Microbiologie Fondamentale et Pathogénicité, UMR 5234, CNRS, Bordeaux, France.
Landrein N; Microbiologie Fondamentale et Pathogénicité, UMR 5234, University of Bordeaux, Bordeaux, France.; Microbiologie Fondamentale et Pathogénicité, UMR 5234, CNRS, Bordeaux, France.
Robinson DR; Microbiologie Fondamentale et Pathogénicité, UMR 5234, University of Bordeaux, Bordeaux, France.; Microbiologie Fondamentale et Pathogénicité, UMR 5234, CNRS, Bordeaux, France.
Rambert J; Aquiderm, INSERM U 1035, University of Bordeaux, Bordeaux, France.
Courtois P; Laboratoire de Parasitologie, UMR IRD CIRAD INTERTRYP 177, University of Bordeaux, Bordeaux, France.; UMR INTERTRYP 177, IRD-CIRAD-University of Bordeaux, Montpellier, France.
Daulouède S; Laboratoire de Parasitologie, UMR IRD CIRAD INTERTRYP 177, University of Bordeaux, Bordeaux, France.; UMR INTERTRYP 177, IRD-CIRAD-University of Bordeaux, Montpellier, France.
Vincendeau P; Laboratoire de Parasitologie, UMR IRD CIRAD INTERTRYP 177, University of Bordeaux, Bordeaux, France.; UMR INTERTRYP 177, IRD-CIRAD-University of Bordeaux, Montpellier, France.; Laboratoire de Parasitologie, CHU de Bordeaux, Bordeaux, France.
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Źródło :
Parasite immunology [Parasite Immunol] 2019 Aug; Vol. 41 (8), pp. e12632. Date of Electronic Publication: 2019 Jun 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Dendritic Cells/*immunology
Monocytes/*immunology
Protozoan Proteins/*immunology
Trypanosoma brucei gambiense/*immunology
Trypanosomiasis, African/*immunology
Animals ; Dendritic Cells/parasitology ; Female ; HLA-DR Antigens/genetics ; HLA-DR Antigens/immunology ; Host-Parasite Interactions ; Humans ; Interleukin-10/genetics ; Interleukin-10/immunology ; Interleukin-12/genetics ; Interleukin-12/immunology ; Lipopolysaccharides/immunology ; Mice ; Monocytes/parasitology ; Protozoan Proteins/genetics ; Signal Transduction ; T-Lymphocytes/immunology ; T-Lymphocytes/parasitology ; Trypanosoma brucei gambiense/genetics ; Trypanosomiasis, African/genetics ; Trypanosomiasis, African/parasitology ; Tumor Necrosis Factor-alpha/genetics ; Tumor Necrosis Factor-alpha/immunology
Czasopismo naukowe
Tytuł :
Case Report: Trypanosoma brucei Gambiense Human African Trypanosomiasis as the Cause of Fever in an Inpatient with Multiple Myeloma and HIV-1 Coinfection.
Autorzy :
Boodman C; J.D. MacLean Centre for Tropical Diseases, Montreal, Canada.; Faculty of Medicine, University of British Columbia, Vancouver, Canada.
Libman M; Division of Infectious Diseases, Department of Medical Microbiology, McGill University Health Centre, Montreal, Canada.; J.D. MacLean Centre for Tropical Diseases, Montreal, Canada.
Ndao M; National Reference Centre for Parasitology, Montreal, Canada.; J.D. MacLean Centre for Tropical Diseases, Montreal, Canada.
Yansouni CP; Division of Infectious Diseases, Department of Medical Microbiology, McGill University Health Centre, Montreal, Canada.; J.D. MacLean Centre for Tropical Diseases, Montreal, Canada.
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Źródło :
The American journal of tropical medicine and hygiene [Am J Trop Med Hyg] 2019 Jul; Vol. 101 (1), pp. 123-125.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
HIV-1*
Trypanosoma brucei gambiense*
HIV Infections/*complications
Multiple Myeloma/*complications
Trypanosomiasis, African/*complications
Coinfection ; Congo/epidemiology ; Female ; Fever ; Humans ; Middle Aged ; Pentamidine/therapeutic use ; Travel ; Trypanocidal Agents/therapeutic use ; Trypanosomiasis, African/diagnosis ; Trypanosomiasis, African/drug therapy ; Trypanosomiasis, African/epidemiology
Czasopismo naukowe
Tytuł :
Cost of a new method of active screening for human African trypanosomiasis in the Democratic Republic of the Congo.
Autorzy :
Snijders R; Department of Public Health, Institute of Tropical Medicine, Antwerp, Belgium.
Fukinsia A; Programme National de Lutte Contre la Trypanosomiase Humaine Africaine, Kinshasa, the Democratic Republic of Congo.
Claeys Y; Department of Public Health, Institute of Tropical Medicine, Antwerp, Belgium.
Mpanya A; Programme National de Lutte Contre la Trypanosomiase Humaine Africaine, Kinshasa, the Democratic Republic of Congo.
Hasker E; Department of Public Health, Institute of Tropical Medicine, Antwerp, Belgium.
Meheus F; Section of Cancer Surveillance, International Agency for Research on Cancer, Lyon, France.
Miaka E; Programme National de Lutte Contre la Trypanosomiase Humaine Africaine, Kinshasa, the Democratic Republic of Congo.
Boelaert M; Department of Public Health, Institute of Tropical Medicine, Antwerp, Belgium.
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Źródło :
PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2020 Dec 14; Vol. 14 (12), pp. e0008832. Date of Electronic Publication: 2020 Dec 14 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Delivery of Health Care/*methods
Mass Screening/*economics
Mass Screening/*methods
Trypanosomiasis, African/*diagnosis
Trypanosomiasis, African/*epidemiology
Agglutination Tests ; Delivery of Health Care/economics ; Democratic Republic of the Congo/epidemiology ; Health Care Costs ; Humans ; Sensitivity and Specificity ; Trypanosoma brucei gambiense
Czasopismo naukowe
Tytuł :
The Actigraphy Sleep Score: A New Biomarker for Diagnosis, Disease Staging, and Monitoring in Human African Trypanosomiasis.
Autorzy :
Njamnshi AK; Brain Research Africa Initiative (BRAIN), Yaoundé, Cameroon and Geneva, Switzerland.; Neuroscience Lab, Faculty of Medicine and Biomedical Sciences, The University of Yaoundé I, Yaoundé, Cameroon.; Department of Neurology, Central Hospital Yaoundé, Yaoundé, Cameroon.
Seke Etet PF; Department of Neurological Sciences (DSNNMM), University of Verona, Verona, Italy.; Brain Research Africa Initiative (BRAIN), Yaoundé, Cameroon and Geneva, Switzerland.
Ngarka L; Brain Research Africa Initiative (BRAIN), Yaoundé, Cameroon and Geneva, Switzerland.; Neuroscience Lab, Faculty of Medicine and Biomedical Sciences, The University of Yaoundé I, Yaoundé, Cameroon.; Department of Neurology, Central Hospital Yaoundé, Yaoundé, Cameroon.
Perrig S; Sleep Studies Laboratory, Geneva University Hospitals, Geneva, Switzerland.; Brain Research Africa Initiative (BRAIN), Yaoundé, Cameroon and Geneva, Switzerland.
Olivera GC; Deparment of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.
Nfor LN; Brain Research Africa Initiative (BRAIN), Yaoundé, Cameroon and Geneva, Switzerland.; Neuroscience Lab, Faculty of Medicine and Biomedical Sciences, The University of Yaoundé I, Yaoundé, Cameroon.; Department of Neurology, Central Hospital Yaoundé, Yaoundé, Cameroon.
Njamnshi WY; Department of Neurology, Central Hospital Yaoundé, Yaoundé, Cameroon.; Neuroscience Lab, Faculty of Medicine and Biomedical Sciences, The University of Yaoundé I, Yaoundé, Cameroon.; Brain Research Africa Initiative (BRAIN), Yaoundé, Cameroon and Geneva, Switzerland.
Acho A; Neuroscience Lab, Faculty of Medicine and Biomedical Sciences, The University of Yaoundé I, Yaoundé, Cameroon.; Department of Neurology, Central Hospital Yaoundé, Yaoundé, Cameroon.
Muyembe JJ; Institut National de la Recherche Biomédicale, Kinshasa, Democratic Republic of Congo.
Bentivoglio M; Department of Neurological Sciences (DSNNMM), University of Verona, Verona, Italy.
Rottenberg M; Deparment of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.
Kennedy PGE; Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, United Kingdom.
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Źródło :
The American journal of tropical medicine and hygiene [Am J Trop Med Hyg] 2020 Dec; Vol. 103 (6), pp. 2244-2252. Date of Electronic Publication: 2020 Oct 15.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Actigraphy/*methods
Biomarkers/*analysis
Trypanosoma brucei gambiense/*isolation & purification
Trypanosomiasis, African/*diagnosis
Adolescent ; Adult ; Child ; Child, Preschool ; Female ; Humans ; Leukocyte Count ; Male ; Middle Aged ; Sleep ; Trypanosomiasis, African/cerebrospinal fluid ; Trypanosomiasis, African/parasitology ; Young Adult
Czasopismo naukowe
Tytuł :
The separation of trypanosomes from blood by anion exchange chromatography: From Sheila Lanham's discovery 50 years ago to a gold standard for sleeping sickness diagnosis.
Autorzy :
Lejon V; Institut de Recherche pour le Développement, UMR INTERTRYP, Université de Montpellier-IRD-CIRAD, Montpellier, France.
Büscher P; Department of Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.
Nzoumbou-Boko R; Institut de Recherche pour le Développement, UMR INTERTRYP, Université de Montpellier-IRD-CIRAD, Montpellier, France.; University of Bordeaux, CHU Bordeaux, IRD UMR INTERTRYP, Laboratoire de Parasitologie, Bordeaux, France.
Bossard G; CIRAD, UMR INTERTRYP, Université de Montpellier, CIRAD, IRD, Montpellier, France.
Jamonneau V; Institut de Recherche pour le Développement, UMR INTERTRYP, Université de Montpellier-IRD-CIRAD, Montpellier, France.
Bucheton B; Institut de Recherche pour le Développement, UMR INTERTRYP, Université de Montpellier-IRD-CIRAD, Montpellier, France.
Truc P; Institut de Recherche pour le Développement, UMR INTERTRYP, Université de Montpellier-IRD-CIRAD, Montpellier, France.
Lemesre JL; Institut de Recherche pour le Développement, UMR INTERTRYP, Université de Montpellier-IRD-CIRAD, Montpellier, France.
Solano P; Institut de Recherche pour le Développement, UMR INTERTRYP, Université de Montpellier-IRD-CIRAD, Montpellier, France.
Vincendeau P; Institut de Recherche pour le Développement, UMR INTERTRYP, Université de Montpellier-IRD-CIRAD, Montpellier, France.; University of Bordeaux, CHU Bordeaux, IRD UMR INTERTRYP, Laboratoire de Parasitologie, Bordeaux, France.
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Źródło :
PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2019 Feb 28; Vol. 13 (2), pp. e0007051. Date of Electronic Publication: 2019 Feb 28 (Print Publication: 2019).
Typ publikacji :
Historical Article; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Anion Exchange Resins*
Trypanosoma brucei gambiense*
Trypanosoma brucei rhodesiense*
Chromatography/*history
Chromatography/*methods
Trypanosomiasis, African/*diagnosis
Animals ; Antigens, Protozoan/chemistry ; Chromatography/instrumentation ; History, 20th Century ; Humans ; Trypanosomiasis, African/parasitology
Czasopismo naukowe
Tytuł :
Parasite specific 7SL-derived small RNA is an effective target for diagnosis of active trypanosomiasis infection.
Autorzy :
Chiweshe SM; The Roslin Institute, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian, United Kingdom.
Steketee PC; The Roslin Institute, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian, United Kingdom.
Jayaraman S; The Roslin Institute, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian, United Kingdom.
Paxton E; The Roslin Institute, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian, United Kingdom.
Neophytou K; Institute of Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom.
Erasmus H; Clinvet Research Innovation, Uitzich Road, Bainsvlei, Bloemfontein, South Africa.
Labuschagne M; Clinvet Research Innovation, Uitzich Road, Bainsvlei, Bloemfontein, South Africa.
Cooper A; Wellcome Centre for Molecular Parasitology, Institute of Biodiversity, Animal Health and Comparative Medicine, College of Medical, Veterinary & Life Sciences, Bearsden Road, University of Glasgow, Glasgow, United Kingdom.
MacLeod A; Wellcome Centre for Molecular Parasitology, Institute of Biodiversity, Animal Health and Comparative Medicine, College of Medical, Veterinary & Life Sciences, Bearsden Road, University of Glasgow, Glasgow, United Kingdom.
Grey FE; The Roslin Institute, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian, United Kingdom.
Morrison LJ; The Roslin Institute, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian, United Kingdom.
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Źródło :
PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2019 Feb 19; Vol. 13 (2), pp. e0007189. Date of Electronic Publication: 2019 Feb 19 (Print Publication: 2019).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cattle Diseases/*diagnosis
RNA, Small Cytoplasmic/*blood
Signal Recognition Particle/*blood
Trypanosoma brucei gambiense/*genetics
Trypanosoma congolense/*genetics
Trypanosomiasis, African/*veterinary
Trypanosomiasis, Bovine/*diagnosis
Animals ; Biomarkers/blood ; Cattle ; Cattle Diseases/parasitology ; Female ; Genome, Protozoan ; Male ; Molecular Diagnostic Techniques ; Real-Time Polymerase Chain Reaction ; Sequence Analysis, RNA ; Trypanocidal Agents/therapeutic use ; Trypanosoma brucei gambiense/drug effects ; Trypanosoma congolense/drug effects ; Trypanosomiasis, African/diagnosis ; Trypanosomiasis, African/drug therapy ; Trypanosomiasis, Bovine/drug therapy
Czasopismo naukowe
Tytuł :
Human African trypanosomiasis caused by Trypanosoma brucei gambiense: The first case report in China.
Autorzy :
Chen N; Department of Infectious Diseases, The First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, 210029, China.
Jin K; Department of Infectious Diseases, The First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, 210029, China.
Xu J; Department of Respiration, Wuxi Xishan People's Hospital, Wuxi, 214011, China.
Zhang J; Department of Hematology Laboratory, The First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, 210029, China.
Weng Y; Department of Infectious Diseases, The First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, 210029, China. Electronic address: .
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Źródło :
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases [Int J Infect Dis] 2019 Feb; Vol. 79, pp. 34-36. Date of Electronic Publication: 2018 Nov 10.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Trypanosoma brucei gambiense*
Communicable Diseases, Imported/*parasitology
Trypanosomiasis, African/*parasitology
Animals ; China ; Communicable Diseases, Imported/diagnosis ; Communicable Diseases, Imported/drug therapy ; Eflornithine/therapeutic use ; Fatal Outcome ; Gabon ; Humans ; Male ; Middle Aged ; Recurrence ; Trypanocidal Agents/therapeutic use ; Trypanosomiasis, African/diagnosis ; Trypanosomiasis, African/drug therapy
Czasopismo naukowe
Tytuł :
Differences in pathogenicity and virulence of Trypanosoma brucei gambiense field isolates in experimentally infected Balb/C mice.
Autorzy :
Kaboré J; Centre International de Recherche-Développement sur l'Elevage en zone Subhumide (CIRDES), 01 BP 454, Bobo-Dioulasso 01, Burkina Faso; Université NAZI BONI de Bobo-Dioulasso, UFR Sciences et Techniques, 01 BP 1091, Bobo-Dioulasso 01, Burkina Faso. Electronic address: .
Camara O; Programme National de Lutte contre la THA, BP 851, Conakry, Guinea. Electronic address: .
Koffi M; Université Jean Lorougnon Guédé, UFR Environnement, BP 150, Daloa, Côte d'Ivoire. Electronic address: .
Sanou D; Université NAZI BONI de Bobo-Dioulasso, UFR Sciences et Techniques, 01 BP 1091, Bobo-Dioulasso 01, Burkina Faso. Electronic address: .
Ilboudo H; Programme National de Lutte contre la THA, BP 851, Conakry, Guinea. Electronic address: .
Sakandé H; Centre International de Recherche-Développement sur l'Elevage en zone Subhumide (CIRDES), 01 BP 454, Bobo-Dioulasso 01, Burkina Faso. Electronic address: .
Camara M; Programme National de Lutte contre la THA, BP 851, Conakry, Guinea. Electronic address: .
De Meeûs T; INTERTRYP, Univ Montpellier, CIRAD, IRD, Montpellier, France. Electronic address: .
Ravel S; INTERTRYP, Univ Montpellier, CIRAD, IRD, Montpellier, France. Electronic address: .
Belem AMG; Université NAZI BONI de Bobo-Dioulasso, UFR Sciences et Techniques, 01 BP 1091, Bobo-Dioulasso 01, Burkina Faso. Electronic address: .
MacLeod A; Wellcome Center for Molecular Parasitology, University of Glasgow, 464 Bearsden Road, Glasgow G60 1QH, UK. Electronic address: .
Bucheton B; INTERTRYP, Univ Montpellier, CIRAD, IRD, Montpellier, France. Electronic address: .
Jamonneau V; INTERTRYP, Univ Montpellier, CIRAD, IRD, Montpellier, France. Electronic address: .
Thévenon S; CIRAD, UMR INTERTRYP, F-34398 Montpellier, France. Electronic address: .
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Źródło :
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases [Infect Genet Evol] 2018 Sep; Vol. 63, pp. 269-276. Date of Electronic Publication: 2018 May 25.
Typ publikacji :
Journal Article
MeSH Terms :
Host-Parasite Interactions*
Phenotype*
Parasitemia/*pathology
Trypanosoma brucei gambiense/*pathogenicity
Trypanosomiasis, African/*pathology
Africa, Western ; Animals ; Body Weight ; Disease Models, Animal ; Erythrocyte Indices ; Erythrocytes/parasitology ; Erythrocytes/pathology ; Humans ; Mice ; Mice, Inbred BALB C ; Multivariate Analysis ; Parasitemia/mortality ; Parasitemia/parasitology ; Principal Component Analysis ; Survival Analysis ; Trypanosoma brucei gambiense/classification ; Trypanosoma brucei gambiense/isolation & purification ; Trypanosomiasis, African/mortality ; Trypanosomiasis, African/parasitology ; Virulence
Czasopismo naukowe
Tytuł :
The complex health seeking pathway of a human African trypanosomiasis patient in Côte d'Ivoire underlines the need of setting up passive surveillance systems.
Autorzy :
Koné M; Unité de Recherche « Trypanosomoses », Institut Pierre Richet, Bouaké, Côte d'Ivoire.; Laboratoire de Biodiversité et Gestion des Ecosystèmes Tropicaux, Unité de Recherche en Génétique et Epidémiologie Moléculaire, Université Jean Lorougnon Guédé, UFR Environnement, Daloa, Côte d'Ivoire.
N'Gouan EK; Projet de Recherches Cliniques sur la Trypanosomiase (PRCT), Daloa, Côte d'Ivoire.
Kaba D; Unité de Recherche « Trypanosomoses », Institut Pierre Richet, Bouaké, Côte d'Ivoire.
Koffi M; Laboratoire de Biodiversité et Gestion des Ecosystèmes Tropicaux, Unité de Recherche en Génétique et Epidémiologie Moléculaire, Université Jean Lorougnon Guédé, UFR Environnement, Daloa, Côte d'Ivoire.
Kouakou L; Programme National d'Élimination de la Trypanosomose Humaine Africaine, Abidjan, Côte d'Ivoire.
N'Dri L; Unité de Recherche « Trypanosomoses », Institut Pierre Richet, Bouaké, Côte d'Ivoire.
Kouamé CM; Unité de Recherche « Trypanosomoses », Institut Pierre Richet, Bouaké, Côte d'Ivoire.
Nanan VK; Direction Départementale de la Marahoué, District sanitaire de Sinfra, Ministère de la Santé et de l'Hygiène Publique, Abidjan, Côte d'Ivoire.
Tapé GA; Direction départementale de la santé de la Marahoué, Centre de Santé Urbain de Bonon, Ministère de la Santé et de l'Hygiène Publique, Abidjan Côte d'Ivoire.
Coulibaly B; Unité de Recherche « Trypanosomoses », Institut Pierre Richet, Bouaké, Côte d'Ivoire.
Courtin F; Unité de Recherche « Trypanosomoses », Institut Pierre Richet, Bouaké, Côte d'Ivoire.; Unité Mixte de Recherche IRD-CIRAD 177, INTERTRYP, Institut de Recherche pour le Développement (IRD) Université de Montpellier, Montpellier, France.
Ahouty B; Laboratoire de Biodiversité et Gestion des Ecosystèmes Tropicaux, Unité de Recherche en Génétique et Epidémiologie Moléculaire, Université Jean Lorougnon Guédé, UFR Environnement, Daloa, Côte d'Ivoire.
Djohan V; Unité de Recherche « Trypanosomoses », Institut Pierre Richet, Bouaké, Côte d'Ivoire.
Bucheton B; Unité Mixte de Recherche IRD-CIRAD 177, INTERTRYP, Institut de Recherche pour le Développement (IRD) Université de Montpellier, Montpellier, France.
Solano P; Unité Mixte de Recherche IRD-CIRAD 177, INTERTRYP, Institut de Recherche pour le Développement (IRD) Université de Montpellier, Montpellier, France.
Büscher P; Department of Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.
Lejon V; Unité Mixte de Recherche IRD-CIRAD 177, INTERTRYP, Institut de Recherche pour le Développement (IRD) Université de Montpellier, Montpellier, France.
Jamonneau V; Unité de Recherche « Trypanosomoses », Institut Pierre Richet, Bouaké, Côte d'Ivoire.; Unité Mixte de Recherche IRD-CIRAD 177, INTERTRYP, Institut de Recherche pour le Développement (IRD) Université de Montpellier, Montpellier, France.
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Źródło :
PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2020 Sep 14; Vol. 14 (9), pp. e0008588. Date of Electronic Publication: 2020 Sep 14 (Print Publication: 2020).
Typ publikacji :
Case Reports; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Delayed Diagnosis/*economics
Neglected Diseases/*diagnosis
Neglected Diseases/*drug therapy
Trypanosomiasis, African/*diagnosis
Trypanosomiasis, African/*drug therapy
Blood/parasitology ; Cerebrospinal Fluid/parasitology ; Child ; Chronic Disease Indicators ; Cote d'Ivoire/epidemiology ; Female ; Humans ; Neglected Diseases/parasitology ; Patient Care Management/economics ; Trypanosoma brucei gambiense/isolation & purification ; Trypanosomiasis, African/parasitology
Czasopismo naukowe
Tytuł :
Performance evaluation of a prototype rapid diagnostic test for combined detection of gambiense human African trypanosomiasis and malaria.
Autorzy :
Lumbala C; Disease Control Directorate, Ministry of Public Health, Democratic Republic of the Congo.; Global Health Institute, Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium.
Matovu E; College of Veterinary Medicine, Animal Resources and Biosecurity, Makerere University, Kampala, Uganda.
Sendagire H; College of Health Sciences, Makerere University, Kampala, Uganda.
Kazibwe AJN; College of Veterinary Medicine, Animal Resources and Biosecurity, Makerere University, Kampala, Uganda.
Likwela JL; Public Health Department, Faculty of Medicine and Pharmacy, University of Kisangani, Kisangani, Democratic Republic of the Congo.
Muhindo Mavoko H; Kinshasa University, Kinshasa, Democratic Republic of the Congo.
Kayembe S; Foundation for Innovative New Diagnostics (FIND), Geneva, Switzerland.
Lutumba P; Kinshasa University, Kinshasa, Democratic Republic of the Congo.
Biéler S; Foundation for Innovative New Diagnostics (FIND), Geneva, Switzerland.
Van Geertruyden JP; Global Health Institute, Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium.
Ndung'u JM; Foundation for Innovative New Diagnostics (FIND), Geneva, Switzerland.
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Źródło :
PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2020 Apr 06; Vol. 14 (4), pp. e0008168. Date of Electronic Publication: 2020 Apr 06 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Diagnostic Tests, Routine/*methods
Malaria/*diagnosis
Trypanosomiasis, African/*diagnosis
Adolescent ; Adult ; Antigens, Protozoan/blood ; Antigens, Protozoan/immunology ; Democratic Republic of the Congo ; Female ; Humans ; Malaria/blood ; Male ; Plasmodium falciparum ; Prospective Studies ; Protozoan Proteins/blood ; Protozoan Proteins/immunology ; Sensitivity and Specificity ; Trypanosoma brucei gambiense ; Trypanosomiasis, African/blood ; Uganda ; Young Adult
Czasopismo naukowe
Tytuł :
Prospective evaluation of a rapid diagnostic test for Trypanosoma brucei gambiense infection developed using recombinant antigens.
Autorzy :
Lumbala C; Programme National de Lutte contre la Trypanosomiase Humaine Africaine, Kinshasa, Democratic Republic of the Congo.; Global Health Institute, University of Antwerp, Antwerp, Belgium.
Biéler S; Foundation for Innovative New Diagnostics (FIND), Geneva, Switzerland.
Kayembe S; Foundation for Innovative New Diagnostics (FIND), Geneva, Switzerland.
Makabuza J; Programme National de Lutte contre la Trypanosomiase Humaine Africaine, Kinshasa, Democratic Republic of the Congo.
Ongarello S; Foundation for Innovative New Diagnostics (FIND), Geneva, Switzerland.
Ndung'u JM; Foundation for Innovative New Diagnostics (FIND), Geneva, Switzerland.
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Źródło :
PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2018 Mar 28; Vol. 12 (3), pp. e0006386. Date of Electronic Publication: 2018 Mar 28 (Print Publication: 2018).
Typ publikacji :
Comparative Study; Evaluation Study; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
MeSH Terms :
Antibodies, Protozoan/*blood
Antigens, Protozoan/*genetics
Trypanosoma brucei gambiense/*immunology
Trypanosomiasis, African/*diagnosis
Algorithms ; Antigens, Protozoan/immunology ; Cost-Benefit Analysis ; Democratic Republic of the Congo ; Humans ; Prospective Studies ; Sensitivity and Specificity ; Trypanosoma brucei gambiense/chemistry ; Trypanosomiasis, African/immunology ; Trypanosomiasis, African/parasitology
Czasopismo naukowe
Tytuł :
Fexinidazole: A New Drug for African Sleeping Sickness on the Horizon.
Autorzy :
Pollastri MP; Northeastern University, Department of Chemistry and Chemical Biology, 102 Hurtig Hall, 360 Huntington Avenue, Boston, MA 02115, USA. Electronic address: .
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Źródło :
Trends in parasitology [Trends Parasitol] 2018 Mar; Vol. 34 (3), pp. 178-179. Date of Electronic Publication: 2017 Dec 20.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Trypanosoma brucei gambiense*
Nitroimidazoles/*therapeutic use
Trypanocidal Agents/*therapeutic use
Trypanosomiasis, African/*drug therapy
Clinical Trials as Topic ; Drug Approval ; Humans
Czasopismo naukowe
Tytuł :
A multicentre, randomised, non-inferiority clinical trial comparing a nifurtimox-eflornithine combination to standard eflornithine monotherapy for late stage Trypanosoma brucei gambiense human African trypanosomiasis in Uganda.
Autorzy :
Kansiime F; Busitema University Faculty of Health Sciences, Box 1460, Mbale, Uganda.
Adibaku S; Moyo District Health Office, P.O. Box 1, Moyo, Uganda.
Wamboga C; Ministry of Health, Box 7272, Kampala, Uganda.
Idi F; Moyo Hospital, P.O. Box 1, Moyo, Uganda.
Kato CD; College of Veterinary Medicine, Animal Resources & Bio-security, Makerere University, P.O. Box 7062, Kampala, Uganda.
Yamuah L; Armauer Hansen Research Institute, Box 1005, Addis Ababa, Ethiopia.
Vaillant M; Competence Centre in Methodology and Statistics, Luxembourg Institute of Health, 1ab Rue Edison, Strassen, L-1445, Grand Duchy of Luxembourg.
Kioy D; Geneva Foundation for Medical Education and Research, 150, route de Ferney, 1211, Geneva 2, Switzerland.
Olliaro P; UNICEF/UNDP/World Bank/WHO Special Programme for Research & Training in Tropical Diseases (TDR), Geneva, Switzerland.
Matovu E; College of Veterinary Medicine, Animal Resources & Bio-security, Makerere University, P.O. Box 7062, Kampala, Uganda. .
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Źródło :
Parasites & vectors [Parasit Vectors] 2018 Feb 22; Vol. 11 (1), pp. 105. Date of Electronic Publication: 2018 Feb 22.
Typ publikacji :
Clinical Trial; Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Trypanosoma brucei gambiense*
Eflornithine/*administration & dosage
Nifurtimox/*administration & dosage
Trypanocidal Agents/*administration & dosage
Trypanosomiasis, African/*drug therapy
Adolescent ; Adult ; Drug Therapy, Combination ; Eflornithine/adverse effects ; Female ; Follow-Up Studies ; Humans ; Male ; Nifurtimox/adverse effects ; Safety ; Treatment Outcome ; Trypanocidal Agents/adverse effects ; Trypanosomiasis, African/epidemiology ; Uganda/epidemiology ; Young Adult
Czasopismo naukowe
Tytuł :
African Trypanosomiasis-Associated Anemia: The Contribution of the Interplay between Parasites and the Mononuclear Phagocyte System.
Autorzy :
Stijlemans B; Laboratory of Cellular and Molecular Immunology, Vrije Universiteit Brussel (VUB), Brussels, Belgium.; Myeloid Cell Immunology Laboratory, VIB Center for Inflammation Research, Brussels, Belgium.
De Baetselier P; Laboratory of Cellular and Molecular Immunology, Vrije Universiteit Brussel (VUB), Brussels, Belgium.; Myeloid Cell Immunology Laboratory, VIB Center for Inflammation Research, Brussels, Belgium.
Magez S; Laboratory of Cellular and Molecular Immunology, Vrije Universiteit Brussel (VUB), Brussels, Belgium.; Laboratory for Biomedical Research, Ghent University Global Campus, Incheon, South Korea.
Van Ginderachter JA; Laboratory of Cellular and Molecular Immunology, Vrije Universiteit Brussel (VUB), Brussels, Belgium.; Myeloid Cell Immunology Laboratory, VIB Center for Inflammation Research, Brussels, Belgium.
De Trez C; Laboratory of Cellular and Molecular Immunology, Vrije Universiteit Brussel (VUB), Brussels, Belgium.
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Źródło :
Frontiers in immunology [Front Immunol] 2018 Feb 15; Vol. 9, pp. 218. Date of Electronic Publication: 2018 Feb 15 (Print Publication: 2018).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Anemia/*immunology
Host-Parasite Interactions/*immunology
Mononuclear Phagocyte System/*immunology
Trypanosoma brucei gambiense/*immunology
Trypanosomiasis, African/*immunology
Anemia/blood ; Anemia/parasitology ; Animals ; Disease Models, Animal ; Erythropoiesis/immunology ; Galectin 3/immunology ; Galectin 3/metabolism ; Interleukin-10/immunology ; Interleukin-10/metabolism ; Macrophage Migration-Inhibitory Factors/immunology ; Macrophage Migration-Inhibitory Factors/metabolism ; Mice ; Mononuclear Phagocyte System/metabolism ; Trypanosoma brucei gambiense/pathogenicity ; Trypanosomiasis, African/blood ; Trypanosomiasis, African/parasitology
Czasopismo naukowe
Tytuł :
Oral fexinidazole for late-stage African Trypanosoma brucei gambiense trypanosomiasis: a pivotal multicentre, randomised, non-inferiority trial.
Autorzy :
Mesu VKBK; Ministry of Health, Kinshasa, Democratic Republic of the Congo.
Kalonji WM; National HAT Control Programme (Programme National de Lutte contre la Trypanosomiase Humaine Africaine [PNLTHA]), Geneva, Switzerland.
Bardonneau C; Drugs for Neglected Diseases initiative (DNDi), Geneva, Switzerland.
Mordt OV; Drugs for Neglected Diseases initiative (DNDi), Geneva, Switzerland.
Blesson S; Drugs for Neglected Diseases initiative (DNDi), Geneva, Switzerland.
Simon F; Drugs for Neglected Diseases initiative (DNDi), Geneva, Switzerland.
Delhomme S; Drugs for Neglected Diseases initiative (DNDi), Geneva, Switzerland.
Bernhard S; Swiss TPH, Basel, Switzerland; University of Basel, Basel, Petersplatz 1, PO Box, CH-4001 Basel, Switzerland.
Kuziena W; Masi Manimba Hospital, Province Kwilu, Democratic Republic of the Congo.
Lubaki JF; Vanga Hospital, Province Kwilu, Democratic Republic of the Congo.
Vuvu SL; Vanga Hospital, Province Kwilu, Democratic Republic of the Congo.
Ngima PN; Bandundu Hospital, Province Kwilu, Democratic Republic of the Congo.
Mbembo HM; Bandundu Hospital, Province Kwilu, Democratic Republic of the Congo.
Ilunga M; Dipumba Hospital (MIBA), Mbuji Mayi, Province Kasaï Oriental, Democratic Republic of the Congo.
Bonama AK; Isangi Hospital, Province Tshopo, Democratic Republic of the Congo.
Heradi JA; Dingila Hospital, Province Bas Uelé, Democratic Republic of the Congo.
Solomo JLL; Dingila Hospital, Province Bas Uelé, Democratic Republic of the Congo.
Mandula G; Mushie Hospital, Province Maï Ndombe, Democratic Republic of the Congo.
Badibabi LK; Katanda Hospital, Province Kasaï Oriental, Democratic Republic of the Congo.
Dama FR; Batangafo Hospital, Préfecture Ouham, Central African Republic.
Lukula PK; Bagata Hospital, Province Kwilu, Democratic Republic of the Congo.
Tete DN; Drugs for Neglected Diseases initiative (DNDi), Kinshasa, Democratic Republic of the Congo.
Lumbala C; Drugs for Neglected Diseases initiative (DNDi), Kinshasa, Democratic Republic of the Congo.
Scherrer B; Bruno Scherrer Conseil, Saint Arnoult en Yvelines, France.
Strub-Wourgaft N; Drugs for Neglected Diseases initiative (DNDi), Geneva, Switzerland.
Tarral A; Drugs for Neglected Diseases initiative (DNDi), Geneva, Switzerland. Electronic address: .
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Źródło :
Lancet (London, England) [Lancet] 2018 Jan 13; Vol. 391 (10116), pp. 144-154. Date of Electronic Publication: 2017 Nov 04.
Typ publikacji :
Clinical Trial, Phase II; Clinical Trial, Phase III; Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Trypanosoma brucei gambiense*
Nifurtimox/*therapeutic use
Nitroimidazoles/*therapeutic use
Trypanocidal Agents/*therapeutic use
Trypanosomiasis, African/*drug therapy
Administration, Oral ; Adult ; Democratic Republic of the Congo ; Drug Administration Schedule ; Drug Therapy, Combination ; Female ; Humans ; Male ; Middle Aged ; Treatment Outcome ; Trypanosomiasis, African/diagnosis ; Trypanosomiasis, African/mortality
Czasopismo naukowe
Tytuł :
Structure-Activity Relationship in Pyrazolo[4,3- c ]pyridines, First Inhibitors of PEX14-PEX5 Protein-Protein Interaction with Trypanocidal Activity.
Autorzy :
Dawidowski M; Center for Integrated Protein Science Munich at Chair of Biomolecular NMR, Department Chemie , Technische Universität München , Lichtenbergstrasse 4 , 85747 Garching , Germany.; Department of Drug Technology and Pharmaceutical Biotechnology , Medical University of Warsaw , Banacha 1 , 02-097 Warszawa , Poland.
Kalel VC; Institute of Biochemistry and Pathobiochemistry, Department of Systems Biochemistry, Faculty of Medicine , Ruhr-University Bochum , 44780 Bochum , Germany.
Napolitano V; Faculty of Biochemistry, Biophysics and Biotechnology , Jagiellonian University , Gronostajowa 7 , Krakow 30-387 , Poland.; Małopolska Center of Biotechnology , Jagiellonian University in Kraków , Gronostajowa 7 , Kraków 30-387 , Poland.
Fino R; Center for Integrated Protein Science Munich at Chair of Biomolecular NMR, Department Chemie , Technische Universität München , Lichtenbergstrasse 4 , 85747 Garching , Germany.
Schorpp K
Emmanouilidis L; Center for Integrated Protein Science Munich at Chair of Biomolecular NMR, Department Chemie , Technische Universität München , Lichtenbergstrasse 4 , 85747 Garching , Germany.
Lenhart D; Center for Integrated Protein Science Munich at Chair of Biomolecular NMR, Department Chemie , Technische Universität München , Lichtenbergstrasse 4 , 85747 Garching , Germany.
Ostertag M; Center for Integrated Protein Science Munich at Chair of Biomolecular NMR, Department Chemie , Technische Universität München , Lichtenbergstrasse 4 , 85747 Garching , Germany.
Kaiser M; Swiss Tropical and Public Health Institute , Socinstrasse 57 , 4051 Basel , Switzerland.; University of Basel , 4001 Basel , Switzerland.
Kolonko M; Department of Biochemistry, Faculty of Chemistry , Wrocław University of Science and Technology , Wybrzeże Wyspiańskiego 27 , 50-370 Wrocław , Poland.
Tippler B; Institute of Biochemistry and Pathobiochemistry, Department of Systems Biochemistry, Faculty of Medicine , Ruhr-University Bochum , 44780 Bochum , Germany.
Schliebs W; Institute of Biochemistry and Pathobiochemistry, Department of Systems Biochemistry, Faculty of Medicine , Ruhr-University Bochum , 44780 Bochum , Germany.
Dubin G; Małopolska Center of Biotechnology , Jagiellonian University in Kraków , Gronostajowa 7 , Kraków 30-387 , Poland.
Mäser P; Swiss Tropical and Public Health Institute , Socinstrasse 57 , 4051 Basel , Switzerland.; University of Basel , 4001 Basel , Switzerland.
Tetko IV
Hadian K
Plettenburg O; Institute of Organic Chemistry , Leibniz Universität Hannover , Schneiderberg 1b , Hannover 30167 , Germany.
Erdmann R; Institute of Biochemistry and Pathobiochemistry, Department of Systems Biochemistry, Faculty of Medicine , Ruhr-University Bochum , 44780 Bochum , Germany.
Sattler M; Center for Integrated Protein Science Munich at Chair of Biomolecular NMR, Department Chemie , Technische Universität München , Lichtenbergstrasse 4 , 85747 Garching , Germany.
Popowicz GM; Center for Integrated Protein Science Munich at Chair of Biomolecular NMR, Department Chemie , Technische Universität München , Lichtenbergstrasse 4 , 85747 Garching , Germany.
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Źródło :
Journal of medicinal chemistry [J Med Chem] 2020 Jan 23; Vol. 63 (2), pp. 847-879. Date of Electronic Publication: 2020 Jan 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Membrane Proteins/*antagonists & inhibitors
Protozoan Proteins/*antagonists & inhibitors
Pyridines/*chemical synthesis
Pyridines/*pharmacology
Trypanocidal Agents/*chemical synthesis
Trypanocidal Agents/*pharmacology
Animals ; Crystallography, X-Ray ; Drug Design ; Humans ; Magnetic Resonance Spectroscopy ; Membrane Proteins/biosynthesis ; Models, Molecular ; Molecular Docking Simulation ; Molecular Dynamics Simulation ; Myoblasts/drug effects ; Myoblasts/parasitology ; Protozoan Proteins/biosynthesis ; Rats ; Structure-Activity Relationship ; Trypanosoma brucei gambiense/drug effects ; Trypanosoma brucei gambiense/metabolism ; Trypanosoma brucei rhodesiense/drug effects
Czasopismo naukowe
Tytuł :
Monitoring the presence of trypanosomes' DNA - Including Trypanosoma brucei gambiense DNA - From the midguts of riverine Glossina trapped in the south east outskirts of Kinshasa City (Democratic Republic of Congo).
Autorzy :
Grébaut P; UMR INTERTRYP IRD/CIRAD TA A17 G, Campus International de Baillarguet, 34398 Montpellier Cedex 5, France.
Andjingbopou Y; Université Marien Ngouabi, Faculté des Sciences de la Santé, B.P. 69, Brazzaville, Congo.
Mansinsa DP; Programme National de Lutte contre la THA, 36 Avenue de la justice, BP 3040 KIN1, Kinshasa, Congo.
Manzambi EZ; Institut National de Recherche Biomédicale, 5345 Avenue De la Démocratie, Kinshasa, Gombe, Congo.
Mpembelé F; Programme National de Lutte contre la THA, 36 Avenue de la justice, BP 3040 KIN1, Kinshasa, Congo.
Lejon V; UMR INTERTRYP IRD/CIRAD TA A17 G, Campus International de Baillarguet, 34398 Montpellier Cedex 5, France.
Geiger A; UMR INTERTRYP IRD/CIRAD TA A17 G, Campus International de Baillarguet, 34398 Montpellier Cedex 5, France; Faculty of Science, University of Yaoundé I, P.O. Box 812, Yaoundé, Cameroon. Electronic address: .
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Źródło :
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases [Infect Genet Evol] 2020 Jan; Vol. 77, pp. 104095. Date of Electronic Publication: 2019 Nov 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Trypanosoma/*classification
Trypanosomiasis/*epidemiology
Tsetse Flies/*parasitology
Animals ; DNA, Protozoan/genetics ; Democratic Republic of the Congo/epidemiology ; Disease Reservoirs/parasitology ; Evolution, Molecular ; Gastrointestinal Tract/parasitology ; Phylogeny ; Prevalence ; Trypanosoma/genetics ; Trypanosoma/isolation & purification ; Trypanosoma brucei gambiense/classification ; Trypanosoma brucei gambiense/genetics ; Trypanosoma brucei gambiense/isolation & purification ; Trypanosomiasis/transmission
Czasopismo naukowe
Tytuł :
Impact of the Ebola outbreak on Trypanosoma brucei gambiense infection medical activities in coastal Guinea, 2014-2015: A retrospective analysis from the Guinean national Human African Trypanosomiasis control program.
Autorzy :
Camara M; Programme National de Lutte contre la Trypanosomiase Humaine Africaine PNLTHA-Ministère de la Santé, Conakry, République de Guinée.
Ouattara E; Univ. Bordeaux, Inserm, Infectious Diseases in Resource Limited Countries, U1219, ISPED, Bordeaux, France.; Department of Tropical Medicine and Clinical International Health, CHU Bordeaux, Bordeaux, France.; Programme PAC-CI/ANRS Research Site, CHU Treichville, Abidjan, Côte d'Ivoire.
Duvignaud A; Univ. Bordeaux, Inserm, Infectious Diseases in Resource Limited Countries, U1219, ISPED, Bordeaux, France.; Department of Tropical Medicine and Clinical International Health, CHU Bordeaux, Bordeaux, France.; Programme PAC-CI/ANRS Research Site, CHU Treichville, Abidjan, Côte d'Ivoire.
Migliani R; Univ. Bordeaux, Inserm, Infectious Diseases in Resource Limited Countries, U1219, ISPED, Bordeaux, France.
Camara O; Programme National de Lutte contre la Trypanosomiase Humaine Africaine PNLTHA-Ministère de la Santé, Conakry, République de Guinée.
Leno M; Programme National de Lutte contre la Trypanosomiase Humaine Africaine PNLTHA-Ministère de la Santé, Conakry, République de Guinée.
Solano P; UMR 177 IRD-CIRAD INTERTRYP, IRD, Montpellier, France.
Bucheton B; UMR 177 IRD-CIRAD INTERTRYP, IRD, Montpellier, France.
Camara M; Programme National de Lutte contre la Trypanosomiase Humaine Africaine PNLTHA-Ministère de la Santé, Conakry, République de Guinée.
Malvy D; Univ. Bordeaux, Inserm, Infectious Diseases in Resource Limited Countries, U1219, ISPED, Bordeaux, France.; Department of Tropical Medicine and Clinical International Health, CHU Bordeaux, Bordeaux, France.; Programme PAC-CI/ANRS Research Site, CHU Treichville, Abidjan, Côte d'Ivoire.
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Źródło :
PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2017 Nov 13; Vol. 11 (11), pp. e0006060. Date of Electronic Publication: 2017 Nov 13 (Print Publication: 2017).
Typ publikacji :
Journal Article
MeSH Terms :
Disease Outbreaks*
Trypanosoma brucei gambiense*
Hemorrhagic Fever, Ebola/*epidemiology
National Health Programs/*statistics & numerical data
Trypanosomiasis, African/*epidemiology
Trypanosomiasis, African/*prevention & control
Delivery of Health Care ; Guinea/epidemiology ; Humans ; Retrospective Studies
Czasopismo naukowe
Tytuł :
Glycerol kinase of African trypanosomes possesses an intrinsic phosphatase activity.
Autorzy :
Balogun EO; Department of Biomedical Chemistry, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan; Department of Biochemistry, Ahmadu Bello University, Zaria 2222, Nigeria. Electronic address: .
Inaoka DK; Department of Biomedical Chemistry, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan; School of Tropical Medicine and Global Health, Nagasaki University 1-12-4, Sakamoto, Nagasaki 852-8523, Japan.
Shiba T; Department of Applied Biology, Graduate School of Science and Technology, Kyoto Institute of Technology, Sakyo-ku, Kyoto 606-8585, Japan.
Tokuoka SM; Department of Lipidomics, Faculty of Medicine, The University of Tokyo, Hongo 7-3-1, Bunkyo-ku, Tokyo, Japan.
Tokumasu F; Department of Lipidomics, Faculty of Medicine, The University of Tokyo, Hongo 7-3-1, Bunkyo-ku, Tokyo, Japan.
Sakamoto K; Faculty of Agriculture and Life Science, Hirosaki University, Hirosaki 036-8561, Japan.
Kido Y; Department of Biomedical Chemistry, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.
Michels PAM; Centre for Immunity, Infection and Evolution and Centre for Translational and Chemical Biology, School of Biological Sciences, University of Edinburgh, King's Buildings, Charlotte Auerbach Road, Edinburgh EH9 3FL, UK.
Watanabe YI; Department of Biomedical Chemistry, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.
Harada S; Department of Applied Biology, Graduate School of Science and Technology, Kyoto Institute of Technology, Sakyo-ku, Kyoto 606-8585, Japan.
Kita K; Department of Biomedical Chemistry, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan; School of Tropical Medicine and Global Health, Nagasaki University 1-12-4, Sakamoto, Nagasaki 852-8523, Japan. Electronic address: .
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Źródło :
Biochimica et biophysica acta. General subjects [Biochim Biophys Acta Gen Subj] 2017 Nov; Vol. 1861 (11 Pt A), pp. 2830-2842. Date of Electronic Publication: 2017 Aug 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Protein Conformation*
Glycerol Kinase/*chemistry
Phosphoric Monoester Hydrolases/*chemistry
Trypanosoma brucei gambiense/*enzymology
Adenosine Diphosphate/metabolism ; Adenosine Triphosphate/metabolism ; Animals ; Crystallography, X-Ray ; Glycerol/metabolism ; Glycerol Kinase/genetics ; Glycerol Kinase/metabolism ; Glycerophosphates/metabolism ; Humans ; Nitrobenzenes/chemistry ; Phosphoric Monoester Hydrolases/metabolism ; Substrate Specificity ; Trypanosoma brucei gambiense/pathogenicity
Czasopismo naukowe
Tytuł :
The study of trypanosome species circulating in domestic animals in two human African trypanosomiasis foci of Côte d'Ivoire identifies pigs and cattle as potential reservoirs of Trypanosoma brucei gambiense.
Autorzy :
N'Djetchi MK; Laboratoire des Interactions Hôte-Microorganisme-Environnement et Evolution, Unité de Formation et de Recherche Environnement, Université Jean Lorougnon Guédé, Daloa, Côte d'Ivoire.
Ilboudo H; Unité de recherches sur les bases biologiques de la lutte intégrée, Centre International de Recherche-Développement sur l'Elevage en zone Subhumide, Bobo-Dioulasso, Burkina Faso.
Koffi M; Laboratoire des Interactions Hôte-Microorganisme-Environnement et Evolution, Unité de Formation et de Recherche Environnement, Université Jean Lorougnon Guédé, Daloa, Côte d'Ivoire.
Kaboré J; Unité de recherches sur les bases biologiques de la lutte intégrée, Centre International de Recherche-Développement sur l'Elevage en zone Subhumide, Bobo-Dioulasso, Burkina Faso.; Unité de Formation et de Recherche Sciences et Techniques, Université Nazi Boni, Bobo-Dioulasso, Burkina-Faso.
Kaboré JW; Unité de recherches sur les bases biologiques de la lutte intégrée, Centre International de Recherche-Développement sur l'Elevage en zone Subhumide, Bobo-Dioulasso, Burkina Faso.
Kaba D; Unité de Recherche « Trypanosomoses », Institut Pierre Richet, Bouaké, Côte d'Ivoire.
Courtin F; Unité de Recherche « Trypanosomoses », Institut Pierre Richet, Bouaké, Côte d'Ivoire.; Unité Mixte de Recherche IRD-CIRAD 177, INTERTRYP, Institut de Recherche pour le Développement (IRD), Montpellier, France.
Coulibaly B; Unité de Recherche « Trypanosomoses », Institut Pierre Richet, Bouaké, Côte d'Ivoire.
Fauret P; Unité de Recherche « Trypanosomoses », Institut Pierre Richet, Bouaké, Côte d'Ivoire.; Unité Mixte de Recherche IRD-CIRAD 177, INTERTRYP, Institut de Recherche pour le Développement (IRD), Montpellier, France.
Kouakou L; Programme National d'Elimination de la Trypanosomose Humaine Africaine, Ministère de la Santé et de l'Hygiène Publique, Abidjan, Côte d'Ivoire.
Ravel S; Unité Mixte de Recherche IRD-CIRAD 177, INTERTRYP, Institut de Recherche pour le Développement (IRD), Montpellier, France.
Deborggraeve S; Biomedical Sciences Department, Institute of Tropical Medicine, Antwerp, Belgium.
Solano P; Unité Mixte de Recherche IRD-CIRAD 177, INTERTRYP, Institut de Recherche pour le Développement (IRD), Montpellier, France.
De Meeûs T; Unité Mixte de Recherche IRD-CIRAD 177, INTERTRYP, Institut de Recherche pour le Développement (IRD), Montpellier, France.
Bucheton B; Unité Mixte de Recherche IRD-CIRAD 177, INTERTRYP, Institut de Recherche pour le Développement (IRD), Montpellier, France.
Jamonneau V; Unité de Recherche « Trypanosomoses », Institut Pierre Richet, Bouaké, Côte d'Ivoire.; Unité Mixte de Recherche IRD-CIRAD 177, INTERTRYP, Institut de Recherche pour le Développement (IRD), Montpellier, France.
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Źródło :
PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2017 Oct 18; Vol. 11 (10), pp. e0005993. Date of Electronic Publication: 2017 Oct 18 (Print Publication: 2017).
Typ publikacji :
Journal Article
MeSH Terms :
Trypanosoma brucei gambiense*
Cattle Diseases/*parasitology
Disease Reservoirs/*veterinary
Swine Diseases/*parasitology
Trypanosomiasis, African/*parasitology
Animals ; Cattle ; Cattle Diseases/epidemiology ; Cote d'Ivoire/epidemiology ; Humans ; Swine ; Swine Diseases/epidemiology ; Trypanosomiasis, African/epidemiology
Czasopismo naukowe
Tytuł :
The Production of Trypanosoma Brucei Rhodesiense, Cause of African Sleeping Sickness, and Trypanosoma Cruzi , Cause of American Chagas Disease, on Different Medias and Testing a New Media
Autorzy :
Özbilgin A; Manisa Celal Bayar Üniversitesi Tıp Fakültesi, Tıbbi Parazitoloji Anabilim Dalı, Manisa, Türkiye
Çavuş İ; Manisa Celal Bayar Üniversitesi Tıp Fakültesi, Tıbbi Parazitoloji Anabilim Dalı, Manisa, Türkiye
Nuraydın A; Manisa Celal Bayar Üniversitesi Tıp Fakültesi, Tıbbi Parazitoloji Anabilim Dalı, Manisa, Türkiye
Özel Y; Manisa Celal Bayar Üniversitesi Tıp Fakültesi, Tıbbi Parazitoloji Anabilim Dalı, Manisa, Türkiye
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Źródło :
Turkiye parazitolojii dergisi [Turkiye Parazitol Derg] 2020 Mar 20; Vol. 44 (1), pp. 7-11.
Typ publikacji :
Journal Article
MeSH Terms :
Chagas Disease/*parasitology
Culture Media/*standards
Trypanosoma brucei rhodesiense/*growth & development
Trypanosoma cruzi/*growth & development
Trypanosomiasis, African/*parasitology
Animals ; Humans ; Insect Vectors/parasitology ; Trypanosoma brucei gambiense/pathogenicity ; Trypanosomiasis, African/transmission ; Tsetse Flies/parasitology ; Turkey ; United States
Czasopismo naukowe
Tytuł :
New WHO guidelines for treatment of gambiense human African trypanosomiasis including fexinidazole: substantial changes for clinical practice.
Autorzy :
Lindner AK; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health; Institute of Tropical Medicine and International Health, Berlin, Germany.
Lejon V; Intertryp, Institut de Recherche pour le Développement, CIRAD, University of Montpellier, Montpellier, France. Electronic address: .
Chappuis F; Hôpitaux Universitaires de Genève, Geneva, Switzerland.
Seixas J; Institute of Hygiene and Tropical Medicine and Global Health and Tropical Medicine R&D Center, NOVA University, Lisbon, Portugal.
Kazumba L; Neurology Department, University of Kinshasa, Kinshasa, Democratic Republic of the Congo.
Barrett MP; Wellcome Centre for Integrative Parasitology, University of Glasgow, Glasgow, UK.
Mwamba E; National HAT Control Program, Ministry of Health, Kinshasa, Democratic Republic of the Congo.
Erphas O; National HAT Control Program, Ministry of Health, Kampala, Uganda.
Akl EA; AUB GRADE Center, Center for Systematic Reviews in Health Policy and Systems Research, American University of Beirut, Beirut, Lebanon.
Villanueva G; Cochrane Response, London, UK.
Bergman H; Cochrane Response, London, UK.
Simarro P; Neglected Tropical Diseases Department, World Health Organization, Geneva, Switzerland.
Kadima Ebeja A; World Health Organization Office for the Democratic Republic of Congo, Kinshasa, Democratic Republic of Congo.
Priotto G; Neglected Tropical Diseases Department, World Health Organization, Geneva, Switzerland.
Franco JR; Neglected Tropical Diseases Department, World Health Organization, Geneva, Switzerland.
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Źródło :
The Lancet. Infectious diseases [Lancet Infect Dis] 2020 Feb; Vol. 20 (2), pp. e38-e46. Date of Electronic Publication: 2019 Dec 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Practice Guidelines as Topic*
Antiprotozoal Agents/*therapeutic use
Nitroimidazoles/*therapeutic use
Trypanosoma brucei gambiense/*isolation & purification
Trypanosomiasis, African/*drug therapy
Trypanosomiasis, African/*etiology
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Child ; Child, Preschool ; Eflornithine/therapeutic use ; Female ; Humans ; Infant ; Infant, Newborn ; Male ; Middle Aged ; Nifurtimox/therapeutic use ; World Health Organization ; Young Adult
Czasopismo naukowe
Tytuł :
Skin deep.
Autorzy :
Casas-Sánchez A; Department of Parasitology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
Acosta-Serrano Á; Department of Parasitology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.; Department of Vector Biology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
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Źródło :
ELife [Elife] 2016 Oct 14; Vol. 5. Date of Electronic Publication: 2016 Oct 14.
Typ publikacji :
Journal Article; Comment
MeSH Terms :
Trypanosoma brucei gambiense*
Tsetse Flies/*parasitology
Animals ; Humans ; Skin ; Trypanosomiasis, African/parasitology
Czasopismo naukowe
Tytuł :
Identification of Trypanosoma brucei gambiense in naturally infected dogs in Nigeria.
Autorzy :
Umeakuana PU; Department of Veterinary Medicine, Faculty of Veterinary Medicine, University of Abuja, Abuja, Nigeria. .; Department of Veterinary Medicine, Faculty of Veterinary Medicine, University of Nigeria, Nsukka, Nigeria. .
Gibson W; School of Biological Sciences, University of Bristol, Bristol, BS8 1TQ, UK.
Ezeokonkwo RC; Department of Veterinary Parasitology and Entomology, Faculty of Veterinary Medicine, University of Nigeria, Nsukka, Nigeria.
Anene BM; Department of Veterinary Medicine, Faculty of Veterinary Medicine, University of Nigeria, Nsukka, Nigeria.
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Źródło :
Parasites & vectors [Parasit Vectors] 2019 Aug 27; Vol. 12 (1), pp. 420. Date of Electronic Publication: 2019 Aug 27.
Typ publikacji :
Journal Article
MeSH Terms :
Dog Diseases/*epidemiology
Dog Diseases/*parasitology
Trypanosomiasis, African/*veterinary
Animals ; DNA, Protozoan/genetics ; DNA, Ribosomal Spacer/genetics ; Dog Diseases/diagnosis ; Dogs ; Female ; Male ; Nigeria/epidemiology ; Trypanosoma brucei gambiense/genetics ; Trypanosoma brucei gambiense/isolation & purification ; Trypanosomiasis, African/epidemiology
Czasopismo naukowe
Tytuł :
Does DNA replication direct locus-specific recombination during host immune evasion by antigenic variation in the African trypanosome?
Autorzy :
Devlin R; The Wellcome Trust Centre for Molecular Parasitology, Institute of Infection, Immunity and Inflammation, University of Glasgow, Sir Graeme Davis Building, 120 University Place, Glasgow, G12 8TA, UK.
Marques CA; The Wellcome Trust Centre for Molecular Parasitology, Institute of Infection, Immunity and Inflammation, University of Glasgow, Sir Graeme Davis Building, 120 University Place, Glasgow, G12 8TA, UK.; Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dundee, UK.
McCulloch R; The Wellcome Trust Centre for Molecular Parasitology, Institute of Infection, Immunity and Inflammation, University of Glasgow, Sir Graeme Davis Building, 120 University Place, Glasgow, G12 8TA, UK. .
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Źródło :
Current genetics [Curr Genet] 2017 Jun; Vol. 63 (3), pp. 441-449. Date of Electronic Publication: 2016 Nov 07.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Antigens/*analysis
Host-Pathogen Interactions/*genetics
Recombination, Genetic/*genetics
Trypanosoma brucei gambiense/*genetics
Trypanosomiasis, African/*genetics
Adaptive Immunity/genetics ; Animals ; Antigenic Variation/genetics ; Antigens/immunology ; DNA Replication/genetics ; Gene Conversion/genetics ; Host-Pathogen Interactions/immunology ; Immune Evasion/genetics ; Trypanosoma brucei gambiense/pathogenicity ; Trypanosomiasis, African/immunology ; Trypanosomiasis, African/parasitology
Czasopismo naukowe
Tytuł :
Strategies for Trypanosoma brucei gambiense elimination.
Autorzy :
Pandey A; Center for Infectious Disease Modeling and Analysis, Yale School of Public Health, New Haven, CT 06520, USA.
Galvani A; Center for Infectious Disease Modeling and Analysis, Yale School of Public Health, New Haven, CT 06520, USA. Electronic address: .
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Źródło :
The Lancet. Global health [Lancet Glob Health] 2017 Jan; Vol. 5 (1), pp. e10-e11. Date of Electronic Publication: 2016 Nov 21.
Typ publikacji :
Journal Article; Comment
MeSH Terms :
Trypanosoma brucei gambiense*
Trypanosomiasis, African*
Animals ; Cost-Benefit Analysis
Czasopismo naukowe
Tytuł :
Environmental sensing by African trypanosomes.
Autorzy :
Roditi I; Institute for Cell Biology, University of Bern, Bern, Switzerland. Electronic address: .
Schumann G; Institute for Cell Biology, University of Bern, Bern, Switzerland.
Naguleswaran A; Institute for Cell Biology, University of Bern, Bern, Switzerland.
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Źródło :
Current opinion in microbiology [Curr Opin Microbiol] 2016 Aug; Vol. 32, pp. 26-30. Date of Electronic Publication: 2016 Apr 27.
Typ publikacji :
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms :
Environment*
Host-Pathogen Interactions/*physiology
Life Cycle Stages/*physiology
Mammals/*parasitology
Trypanosoma brucei gambiense/*physiology
Trypanosoma brucei rhodesiense/*physiology
Tsetse Flies/*parasitology
Animals ; Insect Vectors/parasitology ; Quorum Sensing/physiology ; Trypanosoma brucei brucei/pathogenicity ; Trypanosoma brucei gambiense/pathogenicity ; Trypanosoma brucei rhodesiense/pathogenicity ; Trypanosomiasis, African/parasitology
Czasopismo naukowe
Tytuł :
Village-scale persistence and elimination of gambiense human African trypanosomiasis.
Autorzy :
Davis CN; MathSys CDT, Mathematics Institute, University of Warwick, Coventry, United Kingdom.; Zeeman Institute (SBIDER), University of Warwick, Coventry, United Kingdom.
Rock KS; Zeeman Institute (SBIDER), University of Warwick, Coventry, United Kingdom.; Mathematics Institute, University of Warwick, Coventry, United Kingdom.
Mwamba Miaka E; Programme National de Lutte contre la Trypanosomiase Humaine Africaine (PNLTHA), Ave Coisement Liberation et Bd Triomphal No 1, Commune de Kasavubu, Kinshasa, Demecratic Republic of the Congo.
Keeling MJ; Zeeman Institute (SBIDER), University of Warwick, Coventry, United Kingdom.; Mathematics Institute, University of Warwick, Coventry, United Kingdom.; School of Life Sciences, University of Warwick, Coventry, United Kingdom.
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Źródło :
PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2019 Oct 28; Vol. 13 (10), pp. e0007838. Date of Electronic Publication: 2019 Oct 28 (Print Publication: 2019).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Mass Screening/*methods
Trypanosomiasis, African/*epidemiology
Congo/epidemiology ; Forecasting ; Geographic Mapping ; Health Policy ; Humans ; Incidence ; Population Density ; Prevalence ; Public Health ; Trypanosoma brucei gambiense ; World Health Organization
Czasopismo naukowe
Tytuł :
Anti-Trypanosomal and Antimalarial Properties of Tetralone Derivatives and Structurally Related Benzocycloalkanones.
Autorzy :
Beteck RM; Centre of Excellence for Pharmaceutical Sciences, North-West University, Potchefstroom 2520, South Africa. .
Legoabe LJ; Centre of Excellence for Pharmaceutical Sciences, North-West University, Potchefstroom 2520, South Africa. .
Isaacs M; Centre for Chemico- and Biomedicinal Research, Rhodes University, Grahamstown 6140, South Africa. .
Khanye SD; Centre for Chemico- and Biomedicinal Research, Rhodes University, Grahamstown 6140, South Africa. .; Division of Pharmaceutical Chemistry, Faculty of Pharmacy, Rhodes University, Grahamstown 6140, South Africa. .
Laming D; Department of Biochemistry and Microbiology, Rhodes University, Grahamstown 6140, South Africa. .
Hoppe HC; Centre for Chemico- and Biomedicinal Research, Rhodes University, Grahamstown 6140, South Africa. .; Department of Biochemistry and Microbiology, Rhodes University, Grahamstown 6140, South Africa. .
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Źródło :
Medicina (Kaunas, Lithuania) [Medicina (Kaunas)] 2019 May 24; Vol. 55 (5). Date of Electronic Publication: 2019 May 24.
Typ publikacji :
Journal Article
MeSH Terms :
Malaria/*drug therapy
Tetralones/*pharmacology
Trypanosomiasis, African/*drug therapy
Humans ; Malaria/physiopathology ; Plasmodium falciparum/drug effects ; Plasmodium falciparum/pathogenicity ; Tetralones/therapeutic use ; Trypanosoma brucei gambiense/drug effects ; Trypanosoma brucei gambiense/pathogenicity ; Trypanosomiasis, African/physiopathology
Czasopismo naukowe
Tytuł :
Update on human African trypanosomiasis (sleeping sickness).
Autorzy :
Kennedy PGE; Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Garscube Campus, Glasgow, G61 1QH, Scotland, UK. .
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Źródło :
Journal of neurology [J Neurol] 2019 Sep; Vol. 266 (9), pp. 2334-2337. Date of Electronic Publication: 2019 Jun 17.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Trypanosoma brucei gambiense/*isolation & purification
Trypanosoma brucei rhodesiense/*isolation & purification
Trypanosomiasis, African/*diagnosis
Trypanosomiasis, African/*therapy
Animals ; Benzamides/therapeutic use ; Boron Compounds/therapeutic use ; Humans ; Neglected Diseases/diagnosis ; Neglected Diseases/epidemiology ; Neglected Diseases/therapy ; Trypanosomiasis, African/epidemiology
Czasopismo naukowe
Tytuł :
Gambian human African trypanosomiasis in North West Uganda. Are we on course for the 2020 target?
Autorzy :
Selby R; Vector Biology Department, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, United Kingdom.
Wamboga C; Vector Control Division, Ministry of Health, Wandegeya, Kampala, Uganda.
Erphas O; Vector Control Division, Ministry of Health, Wandegeya, Kampala, Uganda.
Mugenyi A; Co-ordinating Office for Control of Trypanosomiasis Uganda, Wandegeya, Kampala, Uganda.
Jamonneau V; UMR 177 Intertryp, Institut de Recherche pour le Développement (IRD), Montpellier, France.
Waiswa C; Co-ordinating Office for Control of Trypanosomiasis Uganda, Wandegeya, Kampala, Uganda.
Torr SJ; Vector Biology Department, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, United Kingdom.
Lehane M; Vector Biology Department, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, United Kingdom.
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Źródło :
PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2019 Aug 14; Vol. 13 (8), pp. e0007550. Date of Electronic Publication: 2019 Aug 14 (Print Publication: 2019).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Trypanosomiasis, African/*diagnosis
Trypanosomiasis, African/*epidemiology
Female ; Gambia/epidemiology ; Geographic Mapping ; Humans ; Male ; Mass Screening ; Microscopy ; Prevalence ; Public Health ; Trypanosoma brucei gambiense/isolation & purification ; Trypanosomiasis, African/transmission ; Uganda/epidemiology
Czasopismo naukowe
Tytuł :
Thiazolidinone/thiazole based hybrids - New class of antitrypanosomal agents.
Autorzy :
Kryshchyshyn A; Department of Pharmaceutical, Organic and Bioorganic Chemistry, Danylo Halytsky Lviv National Medical University, Pekarska 69, Lviv, 79010, Ukraine.
Kaminskyy D; Department of Pharmaceutical, Organic and Bioorganic Chemistry, Danylo Halytsky Lviv National Medical University, Pekarska 69, Lviv, 79010, Ukraine.
Karpenko O; Enamine Ltd., Chervonotkatska 78, Kyiv, 02094, Ukraine.
Gzella A; Department of Organic Chemistry, Poznan University of Medical Sciences, Grunwaldzka 6, Poznan, 60-780, Poland.
Grellier P; National Museum of Natural History, UMR 7245 CNRS-MNHN, Team BAMEE, CP 52, 57 Rue Cuvier, 75005, Paris, France.
Lesyk R; Department of Pharmaceutical, Organic and Bioorganic Chemistry, Danylo Halytsky Lviv National Medical University, Pekarska 69, Lviv, 79010, Ukraine; Department of Public Health, Dietetics and Lifestyle Disorders, Faculty of Medicine, University of Information Technology and Management in Rzeszow, Sucharskiego 2, 35-225 Rzeszow, Poland. Electronic address: .
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Źródło :
European journal of medicinal chemistry [Eur J Med Chem] 2019 Jul 15; Vol. 174, pp. 292-308. Date of Electronic Publication: 2019 Apr 24.
Typ publikacji :
Journal Article
MeSH Terms :
Thiazolidines/*pharmacology
Trypanocidal Agents/*pharmacology
Animals ; Cell Line ; Humans ; Inhibitory Concentration 50 ; Male ; Mice ; Molecular Structure ; Structure-Activity Relationship ; Thiazolidines/chemical synthesis ; Thiazolidines/chemistry ; Thiazolidines/toxicity ; Trypanocidal Agents/chemical synthesis ; Trypanocidal Agents/chemistry ; Trypanocidal Agents/toxicity ; Trypanosoma brucei brucei/drug effects ; Trypanosoma brucei gambiense/drug effects
Czasopismo naukowe
Tytuł :
Macrophage migrating inhibitory factor expression is associated with Trypanosoma brucei gambiense infection and is controlled by trans-acting expression quantitative trait loci in the Guinean population.
Autorzy :
Kaboré JW; Centre International de Recherche-Développement sur l'Élevage en zone Subhumide (CIRDES), Unité des Maladies à Vecteurs et Biodiversités (UMaVeB), Bobo-Dioulasso, Burkina Faso.
Camara O; Ministère de la Santé et de l'Hygiène Publique, Programme National de Lutte contre la Trypanosomiase Humaine Africaine (PNLTHA), Conakry, Guinea.
Ilboudo H; Institut de Recherche en Sciences de la Santé (IRSS), Unité de Recherche Clinique de Nanoro (URCN), Nanoro, Burkina Faso.
Capewell P; University of Glasgow, Wellcome Trust Centre for Molecular Parasitology, Glasgow, United Kingdom.
Clucas C; University of Glasgow, Wellcome Trust Centre for Molecular Parasitology, Glasgow, United Kingdom.
Cooper A; University of Glasgow, Wellcome Trust Centre for Molecular Parasitology, Glasgow, United Kingdom.
Kaboré J; Centre International de Recherche-Développement sur l'Élevage en zone Subhumide (CIRDES), Unité des Maladies à Vecteurs et Biodiversités (UMaVeB), Bobo-Dioulasso, Burkina Faso; Université Nazi Boni (UNB), Bobo-Dioulasso, Burkina Faso.
Camara M; Ministère de la Santé et de l'Hygiène Publique, Programme National de Lutte contre la Trypanosomiase Humaine Africaine (PNLTHA), Conakry, Guinea.
Jamonneau V; Institut de Recherche pour le Développement (IRD), UMR IRD-CIRAD 177 INTERTRYP, Montpellier, France.
Hertz-Fowler C; University of Liverpool, Institute of Integrative Biology, Liverpool, United Kingdom.
Bélem AMG; Université Nazi Boni (UNB), Bobo-Dioulasso, Burkina Faso.
Matovu E; Makerere University, College of Veterinary Medicine Animal Resources and Biosecurity, Kampala, Uganda.
Macleod A; University of Glasgow, Wellcome Trust Centre for Molecular Parasitology, Glasgow, United Kingdom.
Sidibé I; Centre International de Recherche-Développement sur l'Élevage en zone Subhumide (CIRDES), Unité des Maladies à Vecteurs et Biodiversités (UMaVeB), Bobo-Dioulasso, Burkina Faso.
Noyes H; University of Liverpool, Centre for Genomic Research, Liverpool, United Kingdom.
Bucheton B; Ministère de la Santé et de l'Hygiène Publique, Programme National de Lutte contre la Trypanosomiase Humaine Africaine (PNLTHA), Conakry, Guinea; Institut de Recherche pour le Développement (IRD), UMR IRD-CIRAD 177 INTERTRYP, Montpellier, France. Electronic address: .
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Corporate Authors :
TrypanoGEN Research Group, as member of the H3Africa Consortium
Źródło :
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases [Infect Genet Evol] 2019 Jul; Vol. 71, pp. 108-115. Date of Electronic Publication: 2019 Mar 23.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Chemokine CXCL13/*metabolism
Macrophage Migration-Inhibitory Factors/*metabolism
Quantitative Trait Loci/*immunology
Trypanosoma brucei gambiense/*pathogenicity
Trypanosomiasis, African/*genetics
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Chemokine CXCL13/genetics ; Child ; Child, Preschool ; Female ; Gene Expression Profiling ; Gene Expression Regulation ; Guinea ; Humans ; Macrophage Migration-Inhibitory Factors/genetics ; Male ; Middle Aged ; Trypanosomiasis, African/immunology ; Trypanosomiasis, African/pathology ; Young Adult
Czasopismo naukowe
Tytuł :
Trypanosoma brucei gambiense Spliced Leader RNA Is a More Specific Marker for Cure of Human African Trypanosomiasis Than T. b. gambiense DNA.
Autorzy :
Ilboudo H; Centre International de Recherche-Développement sur l'Elevage en zones Subhumide, Unité de Recherches sur les Bases Biologiques de la Lutte Intégrée.
Camara O; Ministère de la Santé et de l'Hygiène Publique, Programme National de Lutte contre la Trypanosomose Humaine Africaine, Conakry, Guinea.
Ravel S; Unité Mixte de Recherche IRD-CIRAD 177, Institut de Recherche pour le Développement, Montpellier, France.
Bucheton B; Unité Mixte de Recherche IRD-CIRAD 177, Institut de Recherche pour le Développement, Montpellier, France.
Lejon V; Unité Mixte de Recherche IRD-CIRAD 177, Institut de Recherche pour le Développement, Montpellier, France.
Camara M; Ministère de la Santé et de l'Hygiène Publique, Programme National de Lutte contre la Trypanosomose Humaine Africaine, Conakry, Guinea.
Kaboré J; Université Polytechnique de Bobo-Dioulasso, Burkina-Faso.
Jamonneau V; Centre International de Recherche-Développement sur l'Elevage en zones Subhumide, Unité de Recherches sur les Bases Biologiques de la Lutte Intégrée.
Deborggraeve S; Biomedical Sciences Department, Institute of Tropical Medicine Antwerp, Belgium.
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Źródło :
The Journal of infectious diseases [J Infect Dis] 2015 Dec 15; Vol. 212 (12), pp. 1996-8. Date of Electronic Publication: 2015 Jun 16.
Typ publikacji :
Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA, Protozoan/*analysis
Drug Monitoring/*methods
RNA, Spliced Leader/*analysis
Trypanosoma brucei gambiense/*isolation & purification
Trypanosomiasis, African/*drug therapy
DNA, Protozoan/genetics ; Humans ; RNA, Spliced Leader/genetics ; Sensitivity and Specificity ; Trypanosoma brucei gambiense/genetics
Czasopismo naukowe
Tytuł :
Population genetics of Trypanosoma brucei gambiense in sleeping sickness patients with treatment failures in the focus of Mbuji-Mayi, Democratic Republic of the Congo.
Autorzy :
Pyana PP; Département de Parasitologie, Institut National de Recherche Biomédicale, Av. de la Démocratie, BP 1197, Kinshasa Gombe, Congo.
Sere M; Centre International de Recherche-Développement sur l'Élevage en zones Subhumides (CIRDES), Unité de recherches sur les bases biologiques de la lutte intégrée, Institut de Recherche pour le Développement, Unité Mixte de Recherche IRD-CIRAD 177 INTERTRYP, 01 BP 454 Bobo-Dioulasso 01, Burkina Faso.
Kaboré J; Centre International de Recherche-Développement sur l'Élevage en zones Subhumides (CIRDES), Unité de recherches sur les bases biologiques de la lutte intégrée, Institut de Recherche pour le Développement, Unité Mixte de Recherche IRD-CIRAD 177 INTERTRYP, 01 BP 454 Bobo-Dioulasso 01, Burkina Faso; Université Polytechnique de Bobo-Dioulasso, 01 BP 1091 Bobo-Dioulasso 01, Burkina Faso.
De Meeûs T; Centre International de Recherche-Développement sur l'Élevage en zones Subhumides (CIRDES), Unité de recherches sur les bases biologiques de la lutte intégrée, Institut de Recherche pour le Développement, Unité Mixte de Recherche IRD-CIRAD 177 INTERTRYP, 01 BP 454 Bobo-Dioulasso 01, Burkina Faso; Institut de Recherche pour le Développement, Unité Mixte de Recherche IRD-CIRAD 177 INTERTRYP, TA A-17/G, Campus International de Baillarguet, F-34398 Montpellier, France. Electronic address: .
MacLeod A; Wellcome Centre for Molecular Parasitology, University of Glasgow, Biomedical Research Centre, 120 University Place, Glasgow G12 8TA, United Kingdom.
Bucheton B; Programme National de Lutte contre la Trypanosomiase Humaine Africaine, Conakry BP 851, Guinea; Institut de Recherche pour le Développement, Unité Mixte de Recherche IRD-CIRAD 177 INTERTRYP, TA A-17/G, Campus International de Baillarguet, F-34398 Montpellier, France.
Van Reet N; Department of Biomedical Sciences, Institute of Tropical Medicine, Nationalestraat 155, B-2000 Antwerp, Belgium.
Büscher P; Department of Biomedical Sciences, Institute of Tropical Medicine, Nationalestraat 155, B-2000 Antwerp, Belgium.
Belem AMG; Université Polytechnique de Bobo-Dioulasso, 01 BP 1091 Bobo-Dioulasso 01, Burkina Faso.
Jamonneau V; Centre International de Recherche-Développement sur l'Élevage en zones Subhumides (CIRDES), Unité de recherches sur les bases biologiques de la lutte intégrée, Institut de Recherche pour le Développement, Unité Mixte de Recherche IRD-CIRAD 177 INTERTRYP, 01 BP 454 Bobo-Dioulasso 01, Burkina Faso; Institut de Recherche pour le Développement, Unité Mixte de Recherche IRD-CIRAD 177 INTERTRYP, TA A-17/G, Campus International de Baillarguet, F-34398 Montpellier, France.
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Źródło :
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases [Infect Genet Evol] 2015 Mar; Vol. 30, pp. 128-133. Date of Electronic Publication: 2014 Dec 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Trypanosoma brucei gambiense*/classification
Trypanosoma brucei gambiense*/drug effects
Trypanosoma brucei gambiense*/genetics
Drug Resistance/*genetics
Trypanosomiasis, African/*drug therapy
Trypanosomiasis, African/*parasitology
Animals ; Antiprotozoal Agents/pharmacology ; Antiprotozoal Agents/therapeutic use ; Democratic Republic of the Congo/epidemiology ; Disease Models, Animal ; Genetics, Population ; Humans ; Mice ; Phylogeny ; Treatment Failure ; Trypanosomiasis, African/epidemiology
Czasopismo naukowe
Tytuł :
Molecular identification of bovine trypanosomes in relation to cattle sources in southwest Nigeria.
Autorzy :
Odeniran PO; University of Ibadan, Nigeria. Department of Veterinary Parasitology, Faculty of Veterinary Medicine, Ibadan, Nigeria; Deanery of Biomedical Sciences, Edinburgh Medical School, College of Medicine and Veterinary Medicine, The University of Edinburgh, 1 George Square, Edinburgh EH8 9JZ, UK. Electronic address: .
Macleod ET; Deanery of Biomedical Sciences, Edinburgh Medical School, College of Medicine and Veterinary Medicine, The University of Edinburgh, 1 George Square, Edinburgh EH8 9JZ, UK.
Ademola IO; University of Ibadan, Nigeria. Department of Veterinary Parasitology, Faculty of Veterinary Medicine, Ibadan, Nigeria.
Welburn SC; Deanery of Biomedical Sciences, Edinburgh Medical School, College of Medicine and Veterinary Medicine, The University of Edinburgh, 1 George Square, Edinburgh EH8 9JZ, UK; Zhejiang University-University of Edinburgh Joint Institute, International Campus, 718 East Haizhou Road, Haining 314400, China.
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Źródło :
Parasitology international [Parasitol Int] 2019 Feb; Vol. 68 (1), pp. 1-8. Date of Electronic Publication: 2018 Sep 20.
Typ publikacji :
Journal Article
MeSH Terms :
Cattle Diseases/*diagnosis
Coinfection/*veterinary
DNA, Protozoan/*genetics
Trypanosoma/*genetics
Trypanosomiasis, Bovine/*epidemiology
Animals ; Cattle ; Cattle Diseases/blood ; Cattle Diseases/epidemiology ; Cattle Diseases/parasitology ; Coinfection/epidemiology ; Coinfection/parasitology ; DNA, Protozoan/blood ; DNA, Ribosomal Spacer/genetics ; Female ; Longitudinal Studies ; Male ; Polymerase Chain Reaction/methods ; Prevalence ; Seasons ; Trypanosoma/isolation & purification ; Trypanosoma brucei brucei/genetics ; Trypanosoma brucei brucei/isolation & purification ; Trypanosoma brucei gambiense/genetics ; Trypanosoma brucei gambiense/isolation & purification ; Trypanosoma vivax/genetics ; Trypanosoma vivax/isolation & purification ; Trypanosomiasis, Bovine/blood ; Trypanosomiasis, Bovine/diagnosis ; Trypanosomiasis, Bovine/parasitology
Czasopismo naukowe
Tytuł :
Immune trypanolysis test as a promising bioassay to monitor the elimination of gambiense human African trypanosomiasis.
Autorzy :
Dama E; Centre International de Recherche-Développement sur l'Elevage en zones Subhumides (CIRDES), Unité de recherches sur les maladies à vecteurs et biodiversité, 01 BP 454 Bobo-Dioulasso 01, Burkina Faso - Université Nazi Boni, Bobo-Dioulasso, 01 BP 1091 Bobo-Dioulasso, Burkina Faso.
Camara O; Programme National de Lutte contre la Trypanosomose Humaine Africaine, BP 851, Conakry, Guinée.
Kaba D; Institut Pierre Richet, Unité de Recherche « Trypanosomoses », 01 BP 1500, Bouaké, Côte d'Ivoire.
Koffi M; Université Jean Lorougnon Guédé, Laboratoire de biodiversité et Gestion durable des écosystèmes tropicaux, Unité de Recherche en Génétique et Epidémiologie moléculaire, BP 150 Daloa, Côte d'Ivoire.
Camara M; Programme National de Lutte contre la Trypanosomose Humaine Africaine, BP 851, Conakry, Guinée.
Compaoré C; Centre International de Recherche-Développement sur l'Elevage en zones Subhumides (CIRDES), Unité de recherches sur les maladies à vecteurs et biodiversité, 01 BP 454 Bobo-Dioulasso 01, Burkina Faso.
Ilboudo H; Institut de Recherche en Sciences de la Santé (IRSS), Unité de Recherche Clinique de Nanoro (URCN), 11 BP 218 Ouagadougou CMS 11, Burkina Faso.
Courtin F; Institut Pierre Richet, Unité de Recherche « Trypanosomoses », 01 BP 1500, Bouaké, Côte d'Ivoire - Institut de Recherche pour le Développement (IRD), UMR INTERTRYP IRD-CIRAD, Université de Montpellier, TA A-17/G, Campus International de Baillarguet, F-34398 Montpellier, France.
Kaboré J; Centre International de Recherche-Développement sur l'Elevage en zones Subhumides (CIRDES), Unité de recherches sur les maladies à vecteurs et biodiversité, 01 BP 454 Bobo-Dioulasso 01, Burkina Faso - Université Nazi Boni, Bobo-Dioulasso, 01 BP 1091 Bobo-Dioulasso, Burkina Faso.
N'Gouan EK; Projet de Recherche Clinique sur les Trypanosomoses, BP 1425, Daloa, Côte d'Ivoire.
Büscher P; Institute of Tropical Medicine, Department of Biomedical Sciences, Nationalestraat 155, 2000 Antwerp, Belgium.
Lejon V; Institut de Recherche pour le Développement (IRD), UMR INTERTRYP IRD-CIRAD, Université de Montpellier, TA A-17/G, Campus International de Baillarguet, F-34398 Montpellier, France.
Bucheton B; Programme National de Lutte contre la Trypanosomose Humaine Africaine, BP 851, Conakry, Guinée - Institut de Recherche pour le Développement (IRD), UMR INTERTRYP IRD-CIRAD, Université de Montpellier, TA A-17/G, Campus International de Baillarguet, F-34398 Montpellier, France.
Jamonneau V; Institut Pierre Richet, Unité de Recherche « Trypanosomoses », 01 BP 1500, Bouaké, Côte d'Ivoire - Institut de Recherche pour le Développement (IRD), UMR INTERTRYP IRD-CIRAD, Université de Montpellier, TA A-17/G, Campus International de Baillarguet, F-34398 Montpellier, France.
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Transliterated Title :
Le test immunitaire de tryanolyse comme biomarqueur prometteur pour le suivi de l’élimination de la trypanosomose humaine africaine à gambiense.
Źródło :
Parasite (Paris, France) [Parasite] 2019; Vol. 26, pp. 68. Date of Electronic Publication: 2019 Nov 22.
Typ publikacji :
Journal Article
MeSH Terms :
Biological Assay/*methods
Cytotoxicity Tests, Immunologic/*methods
Trypanosoma brucei gambiense/*isolation & purification
Trypanosomiasis, African/*blood
Trypanosomiasis, African/*diagnosis
Africa, Western ; Disease Eradication ; Humans
Czasopismo naukowe
Tytuł :
In vitro and in vivo evaluation of 28DAP010, a novel diamidine for treatment of second-stage African sleeping sickness.
Autorzy :
Wenzler T; Medical Parasitology & Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland University of Basel, Basel, Switzerland .
Yang S; Department of Pharmaceutical Chemistry, School of Pharmacy, The University of Kansas, Lawrence, Kansas, USA.
Patrick DA; Department of Pathology and Laboratory Medicine, School of Medicine, University of North Carolina, Chapel Hill, North Carolina, USA.
Braissant O; University of Basel, Basel, Switzerland Department of Urology, University Hospital of Basel, Basel, Switzerland.
Ismail MA; Department of Chemistry, Georgia State University, Atlanta, Georgia, USA.
Tidwell RR; Department of Pathology and Laboratory Medicine, School of Medicine, University of North Carolina, Chapel Hill, North Carolina, USA.
Boykin DW; Department of Chemistry, Georgia State University, Atlanta, Georgia, USA.
Wang MZ; Department of Pharmaceutical Chemistry, School of Pharmacy, The University of Kansas, Lawrence, Kansas, USA.
Brun R; Medical Parasitology & Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland University of Basel, Basel, Switzerland.
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Źródło :
Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2014 Aug; Vol. 58 (8), pp. 4452-63. Date of Electronic Publication: 2014 May 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Amidines/*pharmacology
Pyridines/*pharmacology
Trypanocidal Agents/*pharmacology
Trypanosoma brucei gambiense/*drug effects
Trypanosoma brucei rhodesiense/*drug effects
Trypanosomiasis, African/*drug therapy
Amidines/chemical synthesis ; Amidines/pharmacokinetics ; Animals ; Dose-Response Relationship, Drug ; Female ; Humans ; Melarsoprol/pharmacokinetics ; Melarsoprol/pharmacology ; Mice ; Pentamidine/pharmacokinetics ; Pentamidine/pharmacology ; Pyridines/chemical synthesis ; Pyridines/pharmacokinetics ; Structure-Activity Relationship ; Trypanocidal Agents/chemical synthesis ; Trypanocidal Agents/pharmacokinetics ; Trypanosoma brucei gambiense/growth & development ; Trypanosoma brucei gambiense/pathogenicity ; Trypanosoma brucei rhodesiense/growth & development ; Trypanosoma brucei rhodesiense/pathogenicity ; Trypanosomiasis, African/parasitology
Czasopismo naukowe
Tytuł :
Proteome characterization in various biological fluids of Trypanosoma brucei gambiense-infected subjects.
Autorzy :
Bonnet J; Institute of Neuroepidemiology and Tropical Neurology, School of Medicine, CNRS FR 3503 GEIST, University of Limoges, INSERM UMR 1094 Tropical Neuroepidemiology, Limoges, France. Electronic address: .
Garcia C; Jacques Monod Institute, Proteomics Facility, University Paris Diderot Sorbonne Paris Cité, Paris, France.. Electronic address: .
Leger T; Jacques Monod Institute, Proteomics Facility, University Paris Diderot Sorbonne Paris Cité, Paris, France.. Electronic address: .
Couquet MP; Institute of Neuroepidemiology and Tropical Neurology, School of Medicine, CNRS FR 3503 GEIST, University of Limoges, INSERM UMR 1094 Tropical Neuroepidemiology, Limoges, France. Electronic address: .
Vignoles P; Institute of Neuroepidemiology and Tropical Neurology, School of Medicine, CNRS FR 3503 GEIST, University of Limoges, INSERM UMR 1094 Tropical Neuroepidemiology, Limoges, France. Electronic address: .
Vatunga G; Instituto de Combate e controlo das Tripanossomiases (ICCT), Luanda, Angola. Electronic address: .
Ndung'u J; Foundation for Innovative New Diagnostics (FIND), Geneva, Switzerland. Electronic address: .
Boudot C; Institute of Neuroepidemiology and Tropical Neurology, School of Medicine, CNRS FR 3503 GEIST, University of Limoges, INSERM UMR 1094 Tropical Neuroepidemiology, Limoges, France. Electronic address: .
Bisser S; Institute of Neuroepidemiology and Tropical Neurology, School of Medicine, CNRS FR 3503 GEIST, University of Limoges, INSERM UMR 1094 Tropical Neuroepidemiology, Limoges, France; Pasteur Institute in French Guiana, 23 Boulevard Pasteur, 973006, Cayenne Cedex, French Guiana. Electronic address: .
Courtioux B; Institute of Neuroepidemiology and Tropical Neurology, School of Medicine, CNRS FR 3503 GEIST, University of Limoges, INSERM UMR 1094 Tropical Neuroepidemiology, Limoges, France. Electronic address: .
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Źródło :
Journal of proteomics [J Proteomics] 2019 Mar 30; Vol. 196, pp. 150-161. Date of Electronic Publication: 2018 Nov 07.
Typ publikacji :
Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Proteomics*
Body Fluids/*metabolism
Proteome/*metabolism
Trypanosoma brucei gambiense/*metabolism
Trypanosomiasis, African/*metabolism
Adolescent ; Adult ; Aged ; Biomarkers/metabolism ; Child ; Female ; Humans ; Male ; Middle Aged ; Prospective Studies
Czasopismo naukowe
Tytuł :
Pharmacokinetic-Pharmacodynamic Assessment of the Hepatic and Bone Marrow Toxicities of the New Trypanoside Fexinidazole.
Autorzy :
Watson JA; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand .; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
Strub-Wourgraft N; Drugs for Neglected Diseases initiative (DNDi), Geneva, Switzerland.
Tarral A; Drugs for Neglected Diseases initiative (DNDi), Geneva, Switzerland.
Ribeiro I; Drugs for Neglected Diseases initiative (DNDi), Geneva, Switzerland.
Tarning J; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
White NJ; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand .; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
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Źródło :
Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2019 Mar 27; Vol. 63 (4). Date of Electronic Publication: 2019 Mar 27 (Print Publication: 2019).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Bone Marrow/*drug effects
Liver/*drug effects
Nitroimidazoles/*adverse effects
Nitroimidazoles/*pharmacokinetics
Trypanocidal Agents/*adverse effects
Trypanocidal Agents/*pharmacokinetics
Administration, Oral ; Animals ; Bayes Theorem ; Bone Marrow/metabolism ; Chagas Disease/drug therapy ; Chagas Disease/metabolism ; Clinical Trials as Topic ; Disease Models, Animal ; Double-Blind Method ; Humans ; Liver/metabolism ; Male ; Nitroimidazoles/pharmacology ; Randomized Controlled Trials as Topic ; Sulfones/adverse effects ; Sulfones/pharmacokinetics ; Sulfones/pharmacology ; Treatment Outcome ; Trypanocidal Agents/pharmacology ; Trypanosoma brucei gambiense/drug effects ; Trypanosomiasis, African/drug therapy ; Trypanosomiasis, African/metabolism
Czasopismo naukowe
Tytuł :
Association between IL1 gene polymorphism and human African trypanosomiasis in populations of sleeping sickness foci of southern Cameroon.
Autorzy :
Ofon E; Molecular Parasitology and Entomology Unit, Department of Biochemistry, Faculty of Science, University of Dschang, Dschang, Cameroon.
Noyes H; Centre for Genomic Research, University of Liverpool, Liverpool, United Kingdom.
Ebo'o Eyanga V; MINSANTE, Divisional Centre for Diseases, PNLTHA, Ministry of Public Health, Yaoundé, Cameroon.
Njiokou F; Laboratory of Molecular Biology, Department of Animal Biology, Faculty of Science, University of Yaoundé I, Yaoundé, Cameroon.
Koffi M; Université Jean Lorougnon Guédé (UJLoG), UFR Environnement-Santé, Laboratoire des Interactions Hôte- Microorganismes-Environnement et Evolution (LIHME) Daloa, Côte d'Ivoire.
Fogue P; Molecular Parasitology and Entomology Unit, Department of Biochemistry, Faculty of Science, University of Dschang, Dschang, Cameroon.
Hertz-Fowler C; Centre for Genomic Research, University of Liverpool, Liverpool, United Kingdom.
MacLeod A; Wellcome Centre for Molecular Parasitology, University Place, Glasgow, United Kingdom.
Matovu E; College of Veterinary Medicine, Animal Resources and Bio-security, Makerere University, Kampala, Uganda.
Simo G; Molecular Parasitology and Entomology Unit, Department of Biochemistry, Faculty of Science, University of Dschang, Dschang, Cameroon.
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Corporate Authors :
TrypanoGEN Research Group, as members of The H3Africa Consortium
Źródło :
PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2019 Mar 25; Vol. 13 (3), pp. e0007283. Date of Electronic Publication: 2019 Mar 25 (Print Publication: 2019).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Neglected Diseases/*genetics
Polymorphism, Single Nucleotide/*genetics
Trypanosoma brucei gambiense/*physiology
Trypanosomiasis, African/*genetics
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Alleles ; Cameroon/epidemiology ; Case-Control Studies ; Child ; Female ; Genetic Association Studies ; Genetic Predisposition to Disease ; Genotype ; Humans ; Male ; Middle Aged ; Neglected Diseases/epidemiology ; Neglected Diseases/parasitology ; Risk ; Trypanosomiasis, African/epidemiology ; Trypanosomiasis, African/parasitology ; Young Adult
Czasopismo naukowe
Tytuł :
Clinical and Neuropathogenetic Aspects of Human African Trypanosomiasis.
Autorzy :
Kennedy PGE; Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom.
Rodgers J; Institute of Biodiversity, Animal Health and Comparative Medicine, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom.
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Źródło :
Frontiers in immunology [Front Immunol] 2019 Jan 25; Vol. 10, pp. 39. Date of Electronic Publication: 2019 Jan 25 (Print Publication: 2019).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Neglected Diseases/*diagnosis
Neglected Diseases/*epidemiology
Trypanosoma brucei gambiense/*pathogenicity
Trypanosoma brucei rhodesiense/*pathogenicity
Trypanosomiasis, African/*diagnosis
Trypanosomiasis, African/*epidemiology
Animals ; Antiprotozoal Agents/administration & dosage ; Antiprotozoal Agents/therapeutic use ; Blood-Brain Barrier/parasitology ; Brain/parasitology ; Delayed Diagnosis ; Humans ; Incidence ; Neglected Diseases/drug therapy ; Neglected Diseases/prevention & control ; Pentamidine/administration & dosage ; Pentamidine/therapeutic use ; Severity of Illness Index ; Suramin/administration & dosage ; Suramin/therapeutic use ; Treatment Outcome ; Trypanosomiasis, African/drug therapy ; Trypanosomiasis, African/prevention & control
Czasopismo naukowe
Tytuł :
Monitoring the Progress towards the Elimination of Gambiense Human African Trypanosomiasis.
Autorzy :
Simarro PP; World Health Organization, Control of Neglected Tropical Diseases, Innovative and Intensified Disease Management, Geneva, Switzerland.
Cecchi G; Food and Agriculture Organization of the United Nations, Sub-regional Office for Eastern Africa, Addis Ababa, Ethiopia.
Franco JR; World Health Organization, Control of Neglected Tropical Diseases, Innovative and Intensified Disease Management, Geneva, Switzerland.
Paone M; Food and Agriculture Organization of the United Nations, Animal Production and Health Division, Rome, Italy.
Diarra A; World Health Organization, Regional Office for Africa, Intercountry Support Team, Libreville, Gabon.
Priotto G; World Health Organization, Control of Neglected Tropical Diseases, Innovative and Intensified Disease Management, Geneva, Switzerland.
Mattioli RC; Food and Agriculture Organization of the United Nations, Animal Production and Health Division, Rome, Italy.
Jannin JG; World Health Organization, Control of Neglected Tropical Diseases, Innovative and Intensified Disease Management, Geneva, Switzerland.
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Źródło :
PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2015 Jun 09; Vol. 9 (6), pp. e0003785. Date of Electronic Publication: 2015 Jun 09 (Print Publication: 2015).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Epidemiological Monitoring*
Trypanosoma brucei gambiense*
Disease Eradication/*methods
Disease Transmission, Infectious/*prevention & control
Trypanosomiasis, African/*epidemiology
Africa South of the Sahara/epidemiology ; Demography ; Disease Eradication/statistics & numerical data ; Geography ; Humans ; Risk Assessment/statistics & numerical data
Czasopismo naukowe
Tytuł :
Accuracy of individual rapid tests for serodiagnosis of gambiense sleeping sickness in West Africa.
Autorzy :
Jamonneau V; Centre International de Recherche-Développement sur l'Elevage en zones Subhumide (CIRDES), Bobo-Dioulasso, Burkina Faso; Institut de Recherche pour le Développement (IRD), Unité Mixte de Recherche IRD-CIRAD 177, Montpellier, France.
Camara O; Programme National de Lutte contre la Trypanosomose Humaine Africaine, Conakry, Guinea.
Ilboudo H; Centre International de Recherche-Développement sur l'Elevage en zones Subhumide (CIRDES), Bobo-Dioulasso, Burkina Faso.
Peylhard M; Centre International de Recherche-Développement sur l'Elevage en zones Subhumide (CIRDES), Bobo-Dioulasso, Burkina Faso; Institut de Recherche pour le Développement (IRD), Unité Mixte de Recherche IRD-CIRAD 177, Montpellier, France.
Koffi M; Université Jean Lorougnon GUEDE (UJLoG), UFR Environnement, Laboratoire des Interactions Hôte-Microorganismes-Environnement et Evolution (LIHME), Daloa, Côte d'Ivoire.
Sakande H; Centre International de Recherche-Développement sur l'Elevage en zones Subhumide (CIRDES), Bobo-Dioulasso, Burkina Faso.
N'Dri L; Institut Pierre Richet (IPR), Unité de Recherche « Trypanosomoses », Bouaké, Côte d'Ivoire.
Sanou D; Centre International de Recherche-Développement sur l'Elevage en zones Subhumide (CIRDES), Bobo-Dioulasso, Burkina Faso.
Dama E; Centre International de Recherche-Développement sur l'Elevage en zones Subhumide (CIRDES), Bobo-Dioulasso, Burkina Faso.
Camara M; Programme National de Lutte contre la Trypanosomose Humaine Africaine, Conakry, Guinea.
Lejon V; Institut de Recherche pour le Développement (IRD), Unité Mixte de Recherche IRD-CIRAD 177, Montpellier, France.
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Źródło :
PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2015 Feb 02; Vol. 9 (2), pp. e0003480. Date of Electronic Publication: 2015 Feb 02 (Print Publication: 2015).
Typ publikacji :
Journal Article
MeSH Terms :
Trypanosoma brucei gambiense*/immunology
Serologic Tests/*methods
Trypanosomiasis, African/*diagnosis
Adult ; Africa, Western ; Animals ; Antibodies, Protozoan/blood ; Female ; Humans ; Middle Aged ; Sensitivity and Specificity ; Trypanosomiasis, African/epidemiology
Czasopismo naukowe
Tytuł :
Human African trypanosomiasis in non-endemic countries.
Autorzy :
Sudarshi D; University College London, London, UK .
Brown M; Hospital for Tropical Diseases, London, UK, and senior lecturer in tropical medicine, London School of Hygiene and Tropical Medicine, London, UK.
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Źródło :
Clinical medicine (London, England) [Clin Med (Lond)] 2015 Feb; Vol. 15 (1), pp. 70-3.
Typ publikacji :
Journal Article
MeSH Terms :
Trypanosoma brucei gambiense*
Trypanosoma brucei rhodesiense*
Trypanosomiasis, African*
Animals ; Chancre/parasitology ; Chancre/pathology ; Emigrants and Immigrants ; Humans ; Tsetse Flies
Czasopismo naukowe
Tytuł :
Loop Mediated Isothermal Amplification for Detection of Trypanosoma brucei gambiense in Urine and Saliva Samples in Nonhuman Primate Model.
Autorzy :
Ngotho M; Animal Science Department, Institute of Primate Research (IPR), P.O. Box 24481, Karen, Nairobi 00502, Kenya.
Kagira JM; Animal Health and Production Department, College of Agriculture and Natural Resources, Jomo Kenyatta University of Agriculture and Technology (JKUAT), P.O. Box 62000, Nairobi 00200, Kenya.
Gachie BM; Biochemistry Department, College of Health Sciences, Jomo Kenyatta University of Agriculture and Technology (JKUAT), P.O. Box 62000, Nairobi 00200, Kenya.
Karanja SM; Public Health Department, College of Health Sciences, Jomo Kenyatta University of Agriculture and Technology (JKUAT), P.O. Box 62000, Nairobi 00200, > Kenya.
Waema MW; Biochemistry Department, College of Health Sciences, Jomo Kenyatta University of Agriculture and Technology (JKUAT), P.O. Box 62000, Nairobi 00200, Kenya.
Maranga DN; Animal Science Department, Institute of Primate Research (IPR), P.O. Box 24481, Karen, Nairobi 00502, Kenya.
Maina NW; Biochemistry Department, College of Health Sciences, Jomo Kenyatta University of Agriculture and Technology (JKUAT), P.O. Box 62000, Nairobi 00200, Kenya.
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Źródło :
BioMed research international [Biomed Res Int] 2015; Vol. 2015, pp. 867846. Date of Electronic Publication: 2015 Oct 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA, Protozoan/*analysis
DNA, Protozoan/*urine
Nucleic Acid Amplification Techniques/*methods
Saliva/*parasitology
Trypanosoma brucei gambiense/*genetics
Trypanosomiasis, African/*diagnosis
Animals ; Chlorocebus aethiops ; DNA, Protozoan/isolation & purification ; Disease Models, Animal ; Parasitology ; Polymerase Chain Reaction/methods ; Reproducibility of Results ; Trypanosoma brucei gambiense/isolation & purification ; Trypanosomiasis, African/parasitology
Czasopismo naukowe
Tytuł :
Molecular basis for the reverse reaction of African human trypanosomes glycerol kinase.
Autorzy :
Balogun EO; Department of Applied Biology, Graduate School of Science and Technology, Kyoto Institute of Technology, Sakyo-ku, Kyoto, 606-8585, Japan; Department of Biomedical Chemistry, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan; Department of Biochemistry, Ahmadu Bello University, Zaria, 2222, Nigeria.
Inaoka DK
Shiba T
Kido Y
Tsuge C
Nara T
Aoki T
Honma T
Tanaka A
Inoue M
Matsuoka S
Michels PA
Kita K
Harada S
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Źródło :
Molecular microbiology [Mol Microbiol] 2014 Dec; Vol. 94 (6), pp. 1315-29. Date of Electronic Publication: 2014 Nov 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Glycerol Kinase/*chemistry
Glycerol Kinase/*metabolism
Protozoan Proteins/*chemistry
Protozoan Proteins/*metabolism
Trypanosoma brucei gambiense/*enzymology
Adenosine Diphosphate/metabolism ; Catalytic Domain ; Crystallography, X-Ray ; Glycerol ; Glycerol Kinase/genetics ; Humans ; Models, Molecular ; Mutagenesis ; Protein Binding ; Protein Structure, Secondary ; Protozoan Proteins/genetics ; Trypanosoma brucei gambiense/chemistry ; Trypanosomiasis, African/parasitology
Czasopismo naukowe
Tytuł :
Unravelling human trypanotolerance: IL8 is associated with infection control whereas IL10 and TNFα are associated with subsequent disease development.
Autorzy :
Ilboudo H; Centre International de Recherche-Développement sur l'Elevage en zones Subhumides (CIRDES), Unité de Recherches sur les Bases Biologiques de la Lutte Intégrée, Bobo-Dioulasso, Burkina Faso.
Bras-Gonçalves R; Institut de Recherche pour le Développement (IRD), UMR IRD-CIRAD 177 INTERTRYP, Campus International de Baillarguet, Montpellier, France.
Camara M; Ministère de la Santé et de l'Hygiène Publique, Programme National de Lutte contre la Trypanosomose Humaine Africaine, Conakry, Guinée.
Flori L; Centre de coopération Internationale en Recherche Agronomique pour le développement (CIRAD), UMR IRD-CIRAD 177 INTERTRYP, Campus International de Baillarguet, Montpellier, France; Institut National de la Recherche Agronomique (INRA), UMR 1313 GABI, F78350 Jouy-en-Josas, France.
Camara O; Ministère de la Santé et de l'Hygiène Publique, Programme National de Lutte contre la Trypanosomose Humaine Africaine, Conakry, Guinée.
Sakande H; Centre International de Recherche-Développement sur l'Elevage en zones Subhumides (CIRDES), Unité de Recherches sur les Bases Biologiques de la Lutte Intégrée, Bobo-Dioulasso, Burkina Faso.
Leno M; Ministère de la Santé et de l'Hygiène Publique, Programme National de Lutte contre la Trypanosomose Humaine Africaine, Conakry, Guinée.
Petitdidier E; Institut de Recherche pour le Développement (IRD), UMR IRD-CIRAD 177 INTERTRYP, Campus International de Baillarguet, Montpellier, France.
Jamonneau V; Centre International de Recherche-Développement sur l'Elevage en zones Subhumides (CIRDES), Unité de Recherches sur les Bases Biologiques de la Lutte Intégrée, Bobo-Dioulasso, Burkina Faso; Institut de Recherche pour le Développement (IRD), UMR IRD-CIRAD 177 INTERTRYP, Campus International de Baillarguet, Montpellier, France.
Bucheton B; Institut de Recherche pour le Développement (IRD), UMR IRD-CIRAD 177 INTERTRYP, Campus International de Baillarguet, Montpellier, France; Ministère de la Santé et de l'Hygiène Publique, Programme National de Lutte contre la Trypanosomose Humaine Africaine, Conakry, Guinée.
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Źródło :
PLoS pathogens [PLoS Pathog] 2014 Nov 06; Vol. 10 (11), pp. e1004469. Date of Electronic Publication: 2014 Nov 06 (Print Publication: 2014).
Typ publikacji :
Clinical Trial; Journal Article
MeSH Terms :
Immunity, Innate*
Interleukin-10/*immunology
Interleukin-8/*immunology
Trypanosoma brucei gambiense/*immunology
Trypanosomiasis, African/*immunology
Tumor Necrosis Factor-alpha/*immunology
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Child ; Child, Preschool ; Female ; Follow-Up Studies ; Humans ; Interleukin-10/blood ; Interleukin-8/blood ; Male ; Middle Aged ; Trypanosoma brucei gambiense/metabolism ; Trypanosomiasis, African/blood ; Tumor Necrosis Factor-alpha/blood
Czasopismo naukowe
Tytuł :
Treatment options for second-stage gambiense human African trypanosomiasis.
Autorzy :
Eperon G; Geneva University Hospitals, Geneva, Switzerland.
Balasegaram M
Potet J
Mowbray C
Valverde O
Chappuis F
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Źródło :
Expert review of anti-infective therapy [Expert Rev Anti Infect Ther] 2014 Nov; Vol. 12 (11), pp. 1407-17. Date of Electronic Publication: 2014 Sep 10.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Trypanosoma brucei gambiense*
Trypanocidal Agents/*therapeutic use
Trypanosomiasis, African/*therapy
Animals ; Disease Progression ; Drug Therapy, Combination ; Humans ; Trypanosomiasis, African/parasitology
Czasopismo naukowe
Tytuł :
Melarsoprol sensitivity profile of Trypanosoma brucei gambiense isolates from cured and relapsed sleeping sickness patients from the Democratic Republic of the Congo.
Autorzy :
Pyana Pati P; Département de Parasitologie, Institut National de Recherche Biomédicale, Kinshasa Gombe, Democratic Republic of the Congo.
Van Reet N; Department of Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.
Mumba Ngoyi D; Département de Parasitologie, Institut National de Recherche Biomédicale, Kinshasa Gombe, Democratic Republic of the Congo.
Ngay Lukusa I; Département de Parasitologie, Institut National de Recherche Biomédicale, Kinshasa Gombe, Democratic Republic of the Congo.
Karhemere Bin Shamamba S; Département de Parasitologie, Institut National de Recherche Biomédicale, Kinshasa Gombe, Democratic Republic of the Congo.
Büscher P; Department of Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.
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Źródło :
PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2014 Oct 02; Vol. 8 (10), pp. e3212. Date of Electronic Publication: 2014 Oct 02 (Print Publication: 2014).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Aquaglyceroporins/*genetics
Melarsoprol/*pharmacology
Trypanocidal Agents/*pharmacology
Trypanosoma brucei gambiense/*drug effects
Trypanosomiasis, African/*parasitology
Adult ; Animals ; Base Sequence ; DNA, Protozoan/chemistry ; DNA, Protozoan/isolation & purification ; Democratic Republic of the Congo ; Drug Resistance/genetics ; Female ; Genotype ; Humans ; Melarsoprol/therapeutic use ; Mice ; Molecular Sequence Data ; Mutant Chimeric Proteins/genetics ; Mutation ; Pentamidine/pharmacology ; Phenotype ; Recurrence ; Sequence Analysis, DNA ; Trypanocidal Agents/therapeutic use ; Trypanosoma brucei gambiense/genetics ; Trypanosomiasis, African/drug therapy
Czasopismo naukowe
Tytuł :
The molecular arms race between African trypanosomes and humans.
Autorzy :
Pays E; Laboratory of Molecular Parasitology, Institut de biologie et de médecine moléculaires (IBMM), Université Libre de Bruxelles (ULB), 12 rue des Professeurs Jeener et Brachet, B6041 Gosselies, Belgium.
Vanhollebeke B; Laboratory of Molecular Parasitology, Institut de biologie et de médecine moléculaires (IBMM), Université Libre de Bruxelles (ULB), 12 rue des Professeurs Jeener et Brachet, B6041 Gosselies, Belgium.
Uzureau P; 1] Laboratory of Molecular Parasitology, Institut de biologie et de médecine moléculaires (IBMM), Université Libre de Bruxelles (ULB), 12 rue des Professeurs Jeener et Brachet, B6041 Gosselies, Belgium. [2] Laboratory of Experimental Medicine, André Vésale Hospital, Université Libre de Bruxelles (ULB), B6110 Montigny-le-Tilleul, Belgium.
Lecordier L; Laboratory of Molecular Parasitology, Institut de biologie et de médecine moléculaires (IBMM), Université Libre de Bruxelles (ULB), 12 rue des Professeurs Jeener et Brachet, B6041 Gosselies, Belgium.
Pérez-Morga D; Laboratory of Molecular Parasitology, Institut de biologie et de médecine moléculaires (IBMM), Université Libre de Bruxelles (ULB), 12 rue des Professeurs Jeener et Brachet, B6041 Gosselies, Belgium.
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Źródło :
Nature reviews. Microbiology [Nat Rev Microbiol] 2014 Aug; Vol. 12 (8), pp. 575-84. Date of Electronic Publication: 2014 Jun 30.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Trypanosoma brucei gambiense/*immunology
Trypanosoma brucei rhodesiense/*immunology
Trypanosomiasis, African/*immunology
Animals ; Apolipoprotein L1 ; Apolipoproteins/genetics ; Apolipoproteins/metabolism ; Biological Evolution ; Disease Resistance/immunology ; Humans ; Lipoproteins, HDL/genetics ; Lipoproteins, HDL/metabolism ; Trypanosoma brucei gambiense/metabolism ; Trypanosoma brucei rhodesiense/metabolism ; Trypanosomiasis, African/genetics ; Trypanosomiasis, African/metabolism
Czasopismo naukowe
Tytuł :
Diagnosis of trypanosomatid infections: targeting the spliced leader RNA.
Autorzy :
González-Andrade P; Biomedical Sciences Department, Institute of Tropical Medicine, Antwerp, Belgium.
Camara M; National Sleeping Sickness Control Program, Ministry of Health and Public Hygiene, Conakry, Guinea.
Ilboudo H; International Center for Development Research on Aging in Sub-Humid Areas (CIRDES), Bobo-Dioulasso, Burkina Faso.
Bucheton B; Institute of Research for Development, Mixed Research Unit IRD-CIRAD 177, Montpellier, France.
Jamonneau V; International Center for Development Research on Aging in Sub-Humid Areas (CIRDES), Bobo-Dioulasso, Burkina Faso; Institute of Research for Development, Mixed Research Unit IRD-CIRAD 177, Montpellier, France.
Deborggraeve S; Biomedical Sciences Department, Institute of Tropical Medicine, Antwerp, Belgium. Electronic address: .
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Źródło :
The Journal of molecular diagnostics : JMD [J Mol Diagn] 2014 Jul; Vol. 16 (4), pp. 400-4. Date of Electronic Publication: 2014 May 09.
Typ publikacji :
Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
RNA, Protozoan/*isolation & purification
RNA, Spliced Leader/*isolation & purification
Trypanosoma brucei gambiense/*isolation & purification
Trypanosomiasis, African/*diagnosis
Humans ; Limit of Detection ; RNA, Protozoan/blood ; RNA, Protozoan/genetics ; RNA, Spliced Leader/blood ; RNA, Spliced Leader/genetics ; Real-Time Polymerase Chain Reaction/methods ; Reverse Transcription ; Trypanosoma brucei gambiense/genetics ; Trypanosomiasis, African/blood ; Trypanosomiasis, African/parasitology
Czasopismo naukowe
Tytuł :
Target-based drug discovery for human African trypanosomiasis: selection of molecular target and chemical matter.
Autorzy :
Gilbert IH; Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dundee DD1 5EH, UK.
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Źródło :
Parasitology [Parasitology] 2014 Jan; Vol. 141 (1), pp. 28-36. Date of Electronic Publication: 2013 Aug 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Drug Delivery Systems*
Drug Discovery*
Trypanocidal Agents/*pharmacokinetics
Trypanosoma brucei gambiense/*drug effects
Trypanosoma brucei rhodesiense/*drug effects
Trypanosomiasis, African/*drug therapy
Biological Availability ; Dosage Forms ; Drug Administration Routes ; Drug Administration Schedule ; Drug Resistance ; Humans ; Structure-Activity Relationship ; Trypanocidal Agents/chemistry ; Trypanocidal Agents/pharmacology ; Trypanosoma brucei gambiense/growth & development ; Trypanosoma brucei gambiense/metabolism ; Trypanosoma brucei rhodesiense/growth & development ; Trypanosoma brucei rhodesiense/metabolism ; Trypanosomiasis, African/parasitology
Czasopismo naukowe
Tytuł :
The elimination of human African trypanosomiasis is in sight: Report from the third WHO stakeholders meeting on elimination of gambiense human African trypanosomiasis.
Autorzy :
Barrett MP; Wellcome Centre for Molecular Parasitology, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom.
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Źródło :
PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2018 Dec 06; Vol. 12 (12), pp. e0006925. Date of Electronic Publication: 2018 Dec 06 (Print Publication: 2018).
Typ publikacji :
Journal Article
MeSH Terms :
Disease Eradication*
Trypanosoma brucei gambiense/*physiology
Trypanosomiasis, African/*prevention & control
Humans ; Trypanosomiasis, African/epidemiology ; Trypanosomiasis, African/parasitology
Czasopismo naukowe
Tytuł :
Aquaporin 2 mutations in Trypanosoma brucei gambiense field isolates correlate with decreased susceptibility to pentamidine and melarsoprol.
Autorzy :
Graf FE; Swiss Tropical and Public Health Institute, Basel, Switzerland ; University of Basel, Basel, Switzerland.
Ludin P
Wenzler T
Kaiser M
Brun R
Pyana PP
Büscher P
de Koning HP
Horn D
Mäser P
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Źródło :
PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2013 Oct 10; Vol. 7 (10), pp. e2475. Date of Electronic Publication: 2013 Oct 10 (Print Publication: 2013).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Drug Resistance*
Mutation*
Aquaporin 2/*genetics
Melarsoprol/*pharmacology
Pentamidine/*pharmacology
Trypanocidal Agents/*pharmacology
Trypanosoma brucei gambiense/*drug effects
Aquaporin 2/metabolism ; DNA, Protozoan/chemistry ; DNA, Protozoan/genetics ; Humans ; Molecular Sequence Data ; Protozoan Proteins/genetics ; Sequence Analysis, DNA ; Trypanosoma brucei gambiense/genetics ; Trypanosoma brucei gambiense/isolation & purification ; Trypanosomiasis, African/parasitology
Czasopismo naukowe
Tytuł :
Mechanism of Trypanosoma brucei gambiense resistance to human serum.
Autorzy :
Uzureau P; Laboratory of Molecular Parasitology, IBMM, Université Libre de Bruxelles, 12 rue des Prof. Jeener et Brachet, B-6041 Gosselies, Belgium.
Uzureau S
Lecordier L
Fontaine F
Tebabi P
Homblé F
Grélard A
Zhendre V
Nolan DP
Lins L
Crowet JM
Pays A
Felu C
Poelvoorde P
Vanhollebeke B
Moestrup SK
Lyngsø J
Pedersen JS
Mottram JC
Dufourc EJ
Pérez-Morga D
Pays E
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Źródło :
Nature [Nature] 2013 Sep 19; Vol. 501 (7467), pp. 430-4. Date of Electronic Publication: 2013 Aug 21.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Apolipoproteins/*blood
Apolipoproteins/*metabolism
Lipoproteins, HDL/*blood
Lipoproteins, HDL/*metabolism
Trypanosoma brucei gambiense/*physiology
Africa ; Animals ; Animals, Genetically Modified ; Apolipoprotein L1 ; Apolipoproteins/antagonists & inhibitors ; Apolipoproteins/toxicity ; Cell Membrane/chemistry ; Cell Membrane/metabolism ; Cysteine Proteases/metabolism ; Haptoglobins/metabolism ; Hemoglobins/metabolism ; Hemolysis ; Humans ; Hydrophobic and Hydrophilic Interactions ; Lipid Metabolism ; Lipoproteins, HDL/antagonists & inhibitors ; Lipoproteins, HDL/chemistry ; Lipoproteins, HDL/toxicity ; Parasites/pathogenicity ; Parasites/physiology ; Protein Structure, Secondary ; Serum/chemistry ; Serum/parasitology ; Trypanosoma brucei gambiense/drug effects ; Trypanosoma brucei gambiense/pathogenicity ; Trypanosomiasis, African/parasitology ; Variant Surface Glycoproteins, Trypanosoma/chemistry ; Variant Surface Glycoproteins, Trypanosoma/metabolism
Czasopismo naukowe
Tytuł :
Luminescent multiplex viability assay for Trypanosoma brucei gambiense.
Autorzy :
Van Reet N; Department of Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium. />Pyana P
Rogé S
Claes F
Büscher P
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Źródło :
Parasites & vectors [Parasit Vectors] 2013 Jul 15; Vol. 6, pp. 207. Date of Electronic Publication: 2013 Jul 15.
Typ publikacji :
Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antiprotozoal Agents/*pharmacology
Parasitology/*methods
Trypanosoma brucei gambiense/*drug effects
Trypanosoma brucei gambiense/*physiology
Adenosine Triphosphate/analysis ; Cell Survival ; Inhibitory Concentration 50 ; Luciferases, Renilla/analysis ; Luciferases, Renilla/genetics ; Luminescent Measurements/methods ; Parasitic Sensitivity Tests/methods ; Recombinant Proteins/analysis ; Recombinant Proteins/genetics ; Staining and Labeling/methods ; Trypanosoma brucei gambiense/chemistry
Czasopismo naukowe
Tytuł :
Biochemical characterization of highly active Trypanosoma brucei gambiense glycerol kinase, a promising drug target.
Autorzy :
Balogun EO; Department of Biomedical Chemistry, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.
Inaoka DK
Shiba T
Kido Y
Nara T
Aoki T
Honma T
Tanaka A
Inoue M
Matsuoka S
Michels PA
Harada S
Kita K
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Źródło :
Journal of biochemistry [J Biochem] 2013 Jul; Vol. 154 (1), pp. 77-84. Date of Electronic Publication: 2013 Apr 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Glycerol Kinase/*chemistry
Protozoan Proteins/*chemistry
Trypanosoma brucei gambiense/*enzymology
Crystallization ; Crystallography, X-Ray ; Drug Design ; Enzyme Inhibitors/pharmacology ; Enzyme Stability ; Genes, Protozoan ; Glycerol Kinase/antagonists & inhibitors ; Glycerol Kinase/metabolism ; Humans ; Hydrogen-Ion Concentration ; Kinetics ; Protozoan Proteins/antagonists & inhibitors ; Protozoan Proteins/metabolism ; Recombinant Proteins/chemistry ; Recombinant Proteins/metabolism ; Trypanosoma brucei gambiense/genetics ; Trypanosoma brucei gambiense/pathogenicity ; Trypanosomiasis, African/drug therapy ; Trypanosomiasis, African/enzymology ; Trypanosomiasis, African/parasitology
Czasopismo naukowe
Tytuł :
Melarsoprol Resistance in African Trypanosomiasis.
Autorzy :
Fairlamb AH; The Wellcome Trust Centre for Anti-Infectives Research, School of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, UK; ORCID: http://orcid.org/0000-0001-5134-0329.
Horn D; The Wellcome Trust Centre for Anti-Infectives Research, School of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, UK; ORCID: http://orcid.org/0000-0001-5173-9284. Electronic address: .
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Źródło :
Trends in parasitology [Trends Parasitol] 2018 Jun; Vol. 34 (6), pp. 481-492. Date of Electronic Publication: 2018 Apr 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Melarsoprol/*therapeutic use
Trypanosomiasis, African/*drug therapy
Trypanosomiasis, African/*parasitology
Aquaglyceroporins/genetics ; Drug Resistance/genetics ; Humans ; Melarsoprol/pharmacology ; Mutation ; Trypanosoma brucei gambiense/drug effects ; Trypanosoma brucei gambiense/genetics
Czasopismo naukowe
Tytuł :
Cyclical appearance of African trypanosomes in the cerebrospinal fluid: new insights in how trypanosomes enter the CNS.
Autorzy :
Mogk S; Interfaculty Institute of Biochemistry, University of Tübingen, Tübingen, Germany.
Meiwes A; Interfaculty Institute of Biochemistry, University of Tübingen, Tübingen, Germany.
Shtopel S; Interfaculty Institute of Biochemistry, University of Tübingen, Tübingen, Germany.
Schraermeyer U; Institute of Ophthalmology, University of Tübingen, Tübingen, Germany.
Lazarus M; International Institute for Integrative Sleep Medicine, University of Tsukuba, Tsukuba, Japan.
Kubata B; AU/NEPAD Agency Regional Office, Nairobi, Kenya.
Wolburg H; Institute of Pathology and Neuropathology, University of Tübingen, Tübingen, Germany.
Duszenko M; Interfaculty Institute of Biochemistry, University of Tübingen, Tübingen, Germany; Faculty of Medicine and Life Sciences, Tongji University, Shanghai, P. R. China.
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Źródło :
PloS one [PLoS One] 2014 Mar 11; Vol. 9 (3), pp. e91372. Date of Electronic Publication: 2014 Mar 11 (Print Publication: 2014).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Trypanosoma brucei gambiense*/immunology
Cerebrospinal Fluid/*parasitology
Trypanosomiasis, African/*parasitology
Animals ; Antibodies, Protozoan/cerebrospinal fluid ; Antibodies, Protozoan/immunology ; Blood-Brain Barrier/metabolism ; Blood-Brain Barrier/pathology ; Blood-Brain Barrier/ultrastructure ; Brain/parasitology ; Brain/pathology ; Brain/ultrastructure ; Central Nervous System/parasitology ; Central Nervous System/pathology ; Cerebrospinal Fluid/immunology ; Claudin-1/metabolism ; Humans ; Pia Mater/parasitology ; Pia Mater/ultrastructure ; Rats ; Trypanosomiasis, African/immunology ; Trypanosomiasis, African/metabolism ; Trypanosomiasis, African/pathology
Czasopismo naukowe
Tytuł :
Mapping the capacities of fixed health facilities to cover people at risk of gambiense human African trypanosomiasis.
Autorzy :
Simarro PP; World Health Organization, Control of Neglected Tropical Diseases, Innovative and Intensified Disease Management, Geneva, Switzerland. .
Cecchi G
Franco JR
Paone M
Diarra A
Ruiz-Postigo JA
Mattioli RC
Jannin JG
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Źródło :
International journal of health geographics [Int J Health Geogr] 2014 Feb 11; Vol. 13, pp. 4. Date of Electronic Publication: 2014 Feb 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Geographic Mapping*
Trypanosoma brucei gambiense*/isolation & purification
Geographic Information Systems/*trends
Health Facilities/*trends
Health Services Accessibility/*trends
Trypanosomiasis, African/*epidemiology
Trypanosomiasis, African/*therapy
Africa/epidemiology ; Health Facilities/standards ; Health Services Accessibility/standards ; Humans ; Population Surveillance/methods ; Risk Factors ; Trypanosomiasis, African/diagnosis
Czasopismo naukowe
Tytuł :
Pharmacokinetics and pharmacodynamics utilizing unbound target tissue exposure as part of a disposition-based rationale for lead optimization of benzoxaboroles in the treatment of Stage 2 Human African Trypanosomiasis.
Autorzy :
Wring S; SCYNEXIS Inc., Research Triangle Park, North Carolina, USA.
Gaukel E; SCYNEXIS Inc., Research Triangle Park, North Carolina, USA.
Nare B; SCYNEXIS Inc., Research Triangle Park, North Carolina, USA.
Jacobs R; SCYNEXIS Inc., Research Triangle Park, North Carolina, USA.
Beaudet B; SCYNEXIS Inc., Research Triangle Park, North Carolina, USA.
Bowling T; SCYNEXIS Inc., Research Triangle Park, North Carolina, USA.
Mercer L; SCYNEXIS Inc., Research Triangle Park, North Carolina, USA.
Bacchi C; Haskins Laboratory, Pace University, New York, New York, USA.
Yarlett N; Haskins Laboratory, Pace University, New York, New York, USA.
Randolph R; SCYNEXIS Inc., Research Triangle Park, North Carolina, USA.
Parham R; SCYNEXIS Inc., Research Triangle Park, North Carolina, USA.
Rewerts C; SCYNEXIS Inc., Research Triangle Park, North Carolina, USA.
Platner J; Anacor Pharmaceuticals, Inc., Palo Alto, California, USA.
Don R; Drugs for Neglected Diseases Initiative, Geneva, Switzerland.
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Źródło :
Parasitology [Parasitology] 2014 Jan; Vol. 141 (1), pp. 104-18. Date of Electronic Publication: 2013 Sep 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Benzamides/*pharmacokinetics
Boron Compounds/*pharmacokinetics
Trypanocidal Agents/*pharmacokinetics
Trypanosoma brucei gambiense/*drug effects
Trypanosoma brucei rhodesiense/*drug effects
Trypanosomiasis, African/*drug therapy
Administration, Oral ; Animals ; Area Under Curve ; Benzamides/administration & dosage ; Benzamides/blood ; Biological Assay ; Blood-Brain Barrier/drug effects ; Boron Compounds/administration & dosage ; Boron Compounds/blood ; Capillary Permeability ; Disease Models, Animal ; Drug Evaluation, Preclinical ; Humans ; Inhibitory Concentration 50 ; Trypanocidal Agents/administration & dosage ; Trypanocidal Agents/blood ; Trypanosoma brucei gambiense/growth & development ; Trypanosoma brucei rhodesiense/growth & development ; Trypanosomiasis, African/blood ; Trypanosomiasis, African/parasitology
Czasopismo naukowe
Tytuł :
Green fluorescent diamidines as diagnostic probes for trypanosomes.
Autorzy :
Giordani F; Department of Chemistry, Georgia State University, Atlanta, Georgia, USA.
Munde M
Wilson WD
Ismail MA
Kumar A
Boykin DW
Barrett MP
Pokaż więcej
Źródło :
Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2014; Vol. 58 (3), pp. 1793-6. Date of Electronic Publication: 2013 Dec 23.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Fluorescent Dyes*
Pentamidine*/analogs & derivatives
Pentamidine*/pharmacology
Microscopy, Fluorescence/*methods
Trypanosoma brucei gambiense/*metabolism
Trypanosomiasis, African/*diagnosis
Humans ; Trypanocidal Agents/pharmacology ; Trypanosoma brucei gambiense/drug effects
Czasopismo naukowe
Tytuł :
Integrating innovations: a qualitative analysis of referral non-completion among rapid diagnostic test-positive patients in Uganda's human African trypanosomiasis elimination programme.
Autorzy :
Lee SJ; Centre of African Studies, University of Edinburgh, George Square, Edinburgh, EH8 9LD, UK. .
Palmer JJ; Centre of African Studies, University of Edinburgh, George Square, Edinburgh, EH8 9LD, UK.; Health in Humanitarian Crises Centre, London School of Hygiene & Tropical Medicine, Keppel Street, London, WC1E 7HT, UK.
Pokaż więcej
Źródło :
Infectious diseases of poverty [Infect Dis Poverty] 2018 Aug 18; Vol. 7 (1), pp. 84. Date of Electronic Publication: 2018 Aug 18.
Typ publikacji :
Journal Article
MeSH Terms :
Diagnostic Tests, Routine/*statistics & numerical data
Referral and Consultation/*statistics & numerical data
Trypanosoma brucei gambiense/*isolation & purification
Trypanosomiasis, African/*diagnosis
Trypanosomiasis, African/*epidemiology
Adolescent ; Adult ; Aged ; Child ; Disease Eradication/organization & administration ; Health Facilities ; Health Personnel/statistics & numerical data ; Humans ; Microscopy ; Middle Aged ; Qualitative Research ; Trypanosomiasis, African/drug therapy ; Trypanosomiasis, African/parasitology ; Uganda/epidemiology
Czasopismo naukowe
Tytuł :
Autophagic-related cell death of Trypanosoma brucei induced by bacteriocin AS-48.
Autorzy :
Martínez-García M; Instituto de Parasitología y Biomedicina 'López-Neyra', CSIC (IPBLN-CSIC), PTS Granada, Granada, Spain.
Bart JM; Centro Nacional de Medicina Tropical, Instituto de Salud Carlos III, Madrid, Spain; UMR INTERTRYP, Institut de Recherche pour le Développement, Montpellier, France.
Campos-Salinas J; Instituto de Parasitología y Biomedicina 'López-Neyra', CSIC (IPBLN-CSIC), PTS Granada, Granada, Spain.
Valdivia E; Departamento de Microbiología, Facultad de Ciencias, Universidad de Granada, Spain.
Martínez-Bueno M; Departamento de Microbiología, Facultad de Ciencias, Universidad de Granada, Spain.
González-Rey E; Instituto de Parasitología y Biomedicina 'López-Neyra', CSIC (IPBLN-CSIC), PTS Granada, Granada, Spain.
Navarro M; Instituto de Parasitología y Biomedicina 'López-Neyra', CSIC (IPBLN-CSIC), PTS Granada, Granada, Spain.
Maqueda M; Departamento de Microbiología, Facultad de Ciencias, Universidad de Granada, Spain.
Cebrián R; Departamento de Microbiología, Facultad de Ciencias, Universidad de Granada, Spain. Electronic address: .
Pérez-Victoria JM; Instituto de Parasitología y Biomedicina 'López-Neyra', CSIC (IPBLN-CSIC), PTS Granada, Granada, Spain. Electronic address: .
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Źródło :
International journal for parasitology. Drugs and drug resistance [Int J Parasitol Drugs Drug Resist] 2018 Aug; Vol. 8 (2), pp. 203-212. Date of Electronic Publication: 2018 Mar 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Autophagy/*drug effects
Bacteriocins/*pharmacology
Cell Death/*drug effects
Trypanocidal Agents/*pharmacology
Trypanosoma brucei brucei/*drug effects
Animals ; Endocytosis/drug effects ; Humans ; Microscopy, Fluorescence ; Temperature ; Trypanosoma brucei brucei/ultrastructure ; Trypanosoma brucei gambiense/drug effects ; Trypanosoma brucei rhodesiense/drug effects ; Trypanosomiasis, African/blood ; Trypanosomiasis, African/drug therapy ; Trypanosomiasis, African/parasitology
Czasopismo naukowe
Tytuł :
Antigenic variation in African trypanosomes: the importance of chromosomal and nuclear context in VSG expression control.
Autorzy :
Glover L; Division of Biological Chemistry & Drug Discovery, College of Life Sciences, University of Dundee, Dow Street, Dundee, DD1 5EH, UK.
Hutchinson S
Alsford S
McCulloch R
Field MC
Horn D
Pokaż więcej
Źródło :
Cellular microbiology [Cell Microbiol] 2013 Dec; Vol. 15 (12), pp. 1984-93. Date of Electronic Publication: 2013 Oct 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Antigenic Variation/*genetics
Trypanosoma brucei gambiense/*genetics
Trypanosomiasis, African/*immunology
Variant Surface Glycoproteins, Trypanosoma/*genetics
Variant Surface Glycoproteins, Trypanosoma/*immunology
Antigenic Variation/immunology ; Chromatin/genetics ; DNA Breaks, Double-Stranded ; DNA Repair ; Humans ; RNA Polymerase I/metabolism ; Recombination, Genetic ; Telomere/genetics ; Transcription, Genetic ; Trypanosoma brucei gambiense/immunology
Czasopismo naukowe
Tytuł :
TLTF in cerebrospinal fluid for detection and staging of T. b. gambiense infection.
Autorzy :
Abdulla MH; Department of Surgery, Colorectal Research Center, King Khalid University Hospital, King Saud University, Riyadh, Kingdom of Saudi Arabia ; Department of Pathology, Center for Discovery and Innovation in Parasitic Diseases, University of California San Francisco, San Francisco, California, United States of America.
Bakhiet M
Lejon V
Andersson J
McKerrow J
Al-Obeed O
Harris RA
Pokaż więcej
Źródło :
PloS one [PLoS One] 2013 Nov 19; Vol. 8 (11), pp. e79281. Date of Electronic Publication: 2013 Nov 19 (Print Publication: 2013).
Typ publikacji :
Clinical Trial; Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Trypanosoma brucei gambiense*
Antibodies, Protozoan/*cerebrospinal fluid
Protozoan Proteins/*cerebrospinal fluid
Trypanosomiasis, African/*cerebrospinal fluid
Trypanosomiasis, African/*diagnosis
Adolescent ; Child ; Child, Preschool ; Female ; Humans ; Infant ; Male
Czasopismo naukowe
Tytuł :
Pharmacokinetics, Trypanosoma brucei gambiense efficacy, and time of drug action of DB829, a preclinical candidate for treatment of second-stage human African trypanosomiasis.
Autorzy :
Wenzler T; Medical Parasitology & Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland.
Yang S
Braissant O
Boykin DW
Brun R
Wang MZ
Pokaż więcej
Źródło :
Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2013 Nov; Vol. 57 (11), pp. 5330-43. Date of Electronic Publication: 2013 Aug 19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Amidines/*pharmacology
Trypanocidal Agents/*pharmacology
Trypanosoma brucei gambiense/*drug effects
Trypanosoma brucei rhodesiense/*drug effects
Trypanosomiasis, African/*drug therapy
Amidines/pharmacokinetics ; Animals ; Drug Administration Schedule ; Drug Evaluation, Preclinical ; Female ; Humans ; Injections, Intraperitoneal ; Melarsoprol/pharmacology ; Mice ; Parasitic Sensitivity Tests ; Pentamidine/pharmacology ; Time Factors ; Trypanocidal Agents/pharmacokinetics ; Trypanosoma brucei gambiense/growth & development ; Trypanosoma brucei rhodesiense/growth & development ; Trypanosomiasis, African/parasitology
Czasopismo naukowe
Tytuł :
The Trypanosoma brucei gambiense secretome impairs lipopolysaccharide-induced maturation, cytokine production, and allostimulatory capacity of dendritic cells.
Autorzy :
Garzón E; UMR 177, IRD-CIRAD, Montpellier, France.
Holzmuller P
Bras-Gonçalves R
Vincendeau P
Cuny G
Lemesre JL
Geiger A
Pokaż więcej
Źródło :
Infection and immunity [Infect Immun] 2013 Sep; Vol. 81 (9), pp. 3300-8. Date of Electronic Publication: 2013 Jun 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Dendritic Cells/*immunology
Interleukin-10/*immunology
Interleukin-6/*immunology
Lipopolysaccharides/*immunology
Trypanosoma brucei gambiense/*immunology
Tumor Necrosis Factor-alpha/*immunology
Animals ; Antigens, CD/immunology ; Female ; Genes, MHC Class II/genetics ; Genes, MHC Class II/immunology ; Interleukin-10/genetics ; Interleukin-6/genetics ; Lymphocytes/immunology ; Male ; Mice ; Mice, Inbred BALB C ; Protein Array Analysis/methods ; Rats, Wistar ; Th1 Cells/immunology ; Th2 Cells/immunology ; Trypanosoma brucei gambiense/genetics ; Trypanosomiasis, African/genetics ; Trypanosomiasis, African/immunology
Czasopismo naukowe
Tytuł :
Human and animal Trypanosomes in Côte d'Ivoire form a single breeding population.
Autorzy :
Capewell P; Wellcome Trust Centre for Molecular Parasitology, College of Medical, Veterinary and Biological Sciences, Glasgow, United Kingdom.
Cooper A
Duffy CW
Tait A
Turner CM
Gibson W
Mehlitz D
Macleod A
Pokaż więcej
Źródło :
PloS one [PLoS One] 2013 Jul 02; Vol. 8 (7), pp. e67852. Date of Electronic Publication: 2013 Jul 02 (Print Publication: 2013).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Trypanosoma brucei brucei/*genetics
Trypanosoma brucei gambiense/*genetics
Trypanosomiasis, African/*parasitology
Animals ; Cote d'Ivoire ; Genetic Markers/genetics ; Genetics, Population ; Genotype ; Humans ; Linkage Disequilibrium ; Microsatellite Repeats/genetics ; Phylogeny ; Principal Component Analysis ; Swine ; Trypanosoma brucei brucei/classification ; Trypanosoma brucei gambiense/classification
Czasopismo naukowe
Tytuł :
Do Cryptic Reservoirs Threaten Gambiense-Sleeping Sickness Elimination?
Autorzy :
Büscher P; Department of Biomedical Sciences, Institute of Tropical Medicine, Nationalestraat 155, 2000 Antwerp, Belgium. Electronic address: .
Bart JM; INTERTRYP, IRD, CIRAD, Univ Montpellier, Montpellier, France; Centro Nacional de Medicina Tropical, Instituto de Salud Carlos III, Calle Sinesio Delgado 4, 28029 Madrid, Spain.
Boelaert M; Department of Public Health, Institute of Tropical Medicine, Nationalestraat 155, 2000 Antwerp, Belgium.
Bucheton B; INTERTRYP, IRD, CIRAD, Univ Montpellier, Montpellier, France.
Cecchi G; Sub-regional Office for Eastern Africa, Food and Agriculture Organization of the United Nations, CMC Road, Bole Sub City, Kebele 12/13, P O Box 5536, Addis Ababa, Ethiopia.
Chitnis N; Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Socinstrasse 57, Postfach, 4002 Basel, Switzerland; University of Basel, Switzerland.
Courtin D; Université Paris Descartes, Institut de Recherche pour le Développement, Unité MERIT, Mère et enfant face aux infections tropicales, 4 avenue de l'Observatoire, 75006 Paris, France.
Figueiredo LM; Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Avenida Prof Egas Moniz, 1649-028 Lisboa, Portugal.
Franco JR; Control of Neglected Tropical Diseases, Innovative and Intensified Disease Management, World Health Organization, Via Appia 20, 1202 Geneva, Switzerland.
Grébaut P; INTERTRYP, IRD, CIRAD, Univ Montpellier, Montpellier, France.
Hasker E; Department of Public Health, Institute of Tropical Medicine, Nationalestraat 155, 2000 Antwerp, Belgium.
Ilboudo H; Institut de Recherche sur les Bases Biologiques de la Lutte Intégrée, Centre International de Recherche-Développement sur l'Élevage en zone Subhumide, 01 BP 454 Bobo-Dioulasso 01, Burkina Faso.
Jamonneau V; INTERTRYP, IRD, CIRAD, Univ Montpellier, Montpellier, France.
Koffi M; Université Jean Lorougnon Guédé, BP 150 Daloa, Côte d'Ivoire.
Lejon V; INTERTRYP, IRD, CIRAD, Univ Montpellier, Montpellier, France.
MacLeod A; Institute of Biodiversity, Animal Health and Comparative Medicine, University of Glasgow, Henry Wellcome Building, 464 Bearsden Road, Glasgow, UK.
Masumu J; Département de Parasitologie, Institut National de Recherche Biomédicale, Avenue de la Démocratie, BP 1197 Kinshasa 1, République Démocratique du Congo.
Matovu E; College of Veterinary Medicine, Animal Resources and Biosecurity, Makerere University, P O Box 7062 Kampala, Uganda.
Mattioli R; Animal Production and Health Division, Food and Agriculture Organization of the United Nations, Viale delle Terme di Caracalla, 00153 Rome, Italy.
Noyes H; Institute of Integrative Biology, University of Liverpool, Liverpool L69 7ZB, UK.
Picado A; Foundation for Innovative New Diagnostics, 9 Chemin des Mines, 1202 Geneva, Switzerland.
Rock KS; Zeeman Institute for Systems Biology & Infectious Disease Research, University of Warwick, Gibbet Hill Road, Coventry CV4 7AL, UK.
Rotureau B; Trypanosome Transmission Group, Trypanosome Cell Biology Unit, INSERM U1201 and Department of Parasites and Insect Vectors, Institut Pasteur, 25, rue du Docteur Roux, 75015 Paris, France.
Simo G; Department of Biochemistry, Faculty of Science, University of Dschang, P O Box 67 Dschang, Cameroon.
Thévenon S; INTERTRYP, IRD, CIRAD, Univ Montpellier, Montpellier, France; CIRAD, INTERTRYP, Montpellier, France.
Trindade S; Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Avenida Prof Egas Moniz, 1649-028 Lisboa, Portugal.
Truc P; INTERTRYP, IRD, CIRAD, Univ Montpellier, Montpellier, France.
Van Reet N; Department of Biomedical Sciences, Institute of Tropical Medicine, Nationalestraat 155, 2000 Antwerp, Belgium.
Pokaż więcej
Corporate Authors :
Informal Expert Group on Gambiense HAT Reservoirs
Źródło :
Trends in parasitology [Trends Parasitol] 2018 Mar; Vol. 34 (3), pp. 197-207. Date of Electronic Publication: 2018 Jan 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Disease Eradication*
Disease Reservoirs*
Trypanosomiasis, African/*prevention & control
Trypanosomiasis, African/*transmission
Animals ; Humans ; Risk Factors ; Trypanosoma brucei gambiense/physiology ; Trypanosomiasis, African/epidemiology ; Trypanosomiasis, African/parasitology
Czasopismo naukowe
Tytuł :
Synthesis of proline derived benzenesulfonamides: A potent anti-Trypanosoma brucei gambiense agent.
Autorzy :
Ugwu DI; Department of Pure and Industrial Chemistry, University of Nigeria, Nsukka, Nigeria; Department of Chemistry, Indian Institute of Technology, Kanpur, India. Electronic address: .
Okoro UC; Department of Pure and Industrial Chemistry, University of Nigeria, Nsukka, Nigeria.
Mishra NK; Department of Chemistry, Indian Institute of Technology, Kanpur, India.
Pokaż więcej
Źródło :
European journal of medicinal chemistry [Eur J Med Chem] 2018 Jun 25; Vol. 154, pp. 110-116. Date of Electronic Publication: 2018 May 14.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Inflammatory Agents, Non-Steroidal/*pharmacology
Antiprotozoal Agents/*pharmacology
Edema/*drug therapy
Proline/*pharmacology
Sulfonamides/*pharmacology
Trypanosoma brucei gambiense/*drug effects
Animals ; Anti-Inflammatory Agents, Non-Steroidal/chemical synthesis ; Anti-Inflammatory Agents, Non-Steroidal/chemistry ; Antiprotozoal Agents/chemical synthesis ; Antiprotozoal Agents/chemistry ; Carrageenan ; Dose-Response Relationship, Drug ; Edema/chemically induced ; Male ; Mice ; Molecular Structure ; Parasitic Sensitivity Tests ; Proline/chemical synthesis ; Proline/chemistry ; Rats ; Structure-Activity Relationship ; Sulfonamides/chemistry
Czasopismo naukowe
Tytuł :
Mortality trends and risk factors in advanced stage-2 Human African Trypanosomiasis: A critical appraisal of 23 years of experience in the Democratic Republic of Congo.
Autorzy :
Kazumba LM; Départment de Neurologie, Université de Kinshasa, Kinshasa, République Démocratique du Congo (RDC).
Kaka JT; Institut Supérieur de Techniques Médicales, Kinshasa, Démocratique du Congo (RDC).
Ngoyi DM; Départment de Médecine Tropicale, Université de Kinshasa, Kinshasa, Démocratique du Congo (RDC).; Institut National de Recherches Biomédicales (INRB), Kinshasa, Démocratique du Congo (RDC).
Tshala-Katumbay D; Départment de Neurologie, Université de Kinshasa, Kinshasa, République Démocratique du Congo (RDC).; Institut National de Recherches Biomédicales (INRB), Kinshasa, Démocratique du Congo (RDC).; Départment of Neurology and School of Public Health, Oregon Health & Science University, Portland, OR, United States of America.
Pokaż więcej
Źródło :
PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2018 Jun 13; Vol. 12 (6), pp. e0006504. Date of Electronic Publication: 2018 Jun 13 (Print Publication: 2018).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Trypanosomiasis, African/*epidemiology
Trypanosomiasis, African/*mortality
Adolescent ; Adult ; Democratic Republic of the Congo/epidemiology ; Disease Management ; Drug Therapy, Combination ; Eflornithine/administration & dosage ; Eflornithine/therapeutic use ; Female ; Hospital Records ; Humans ; Male ; Melarsoprol/administration & dosage ; Melarsoprol/therapeutic use ; Middle Aged ; Multivariate Analysis ; Nifurtimox/administration & dosage ; Nifurtimox/therapeutic use ; Recurrence ; Retrospective Studies ; Risk Factors ; Treatment Outcome ; Trypanocidal Agents/administration & dosage ; Trypanocidal Agents/therapeutic use ; Trypanosoma brucei gambiense/drug effects ; Trypanosomiasis, African/drug therapy ; Trypanosomiasis, African/parasitology ; Young Adult
Czasopismo naukowe
Tytuł :
The development of high resolution maps of tsetse abundance to guide interventions against human African trypanosomiasis in northern Uganda.
Autorzy :
Stanton MC; Lancaster Medical School, Lancaster University, Lancaster, UK. .
Esterhuizen J; Vector Biology Department, Liverpool School of Tropical Medicine, Liverpool, UK.
Tirados I; Vector Biology Department, Liverpool School of Tropical Medicine, Liverpool, UK.
Betts H; Parasitology Department, Liverpool School of Tropical Medicine, Liverpool, UK.
Torr SJ; Vector Biology Department, Liverpool School of Tropical Medicine, Liverpool, UK.
Pokaż więcej
Źródło :
Parasites & vectors [Parasit Vectors] 2018 Jun 08; Vol. 11 (1), pp. 340. Date of Electronic Publication: 2018 Jun 08.
Typ publikacji :
Journal Article
MeSH Terms :
Insect Vectors/*parasitology
Trypanosoma brucei gambiense/*physiology
Trypanosomiasis, African/*transmission
Tsetse Flies/*physiology
Animal Distribution ; Animals ; Ecosystem ; Insect Control ; Insect Vectors/physiology ; Models, Statistical ; Trypanosomiasis, African/epidemiology ; Trypanosomiasis, African/parasitology ; Tsetse Flies/parasitology ; Uganda/epidemiology
Czasopismo naukowe
Tytuł :
Assessing Strategies Against Gambiense Sleeping Sickness Through Mathematical Modeling.
Autorzy :
Rock KS; Zeeman Institute for Systems Biology and Infectious Disease Epidemiology Research, Coventry, United Kingdom.; School of Life Sciences, University of Warwick, Coventry, United Kingdom.
Ndeffo-Mbah ML; Yale School of Public Health, Yale University, New Haven, Connecticut.
Castaño S; Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Switzerland.; University of Basel, Switzerland.
Palmer C; Institute of Disease Modeling, Bellevue, Washington.
Pandey A; Yale School of Public Health, Yale University, New Haven, Connecticut.
Atkins KE; Department of Infectious Disease Epidemiology, Faculty of Epidemiology and Population Health, United Kingdom.; Centre for Mathematical Modelling of Infectious Diseases, London School of Hygiene and Tropical Medicine, United Kingdom.
Ndung'u JM; Foundation for Innovative New Diagnostics, Geneva, Switzerland.
Hollingsworth TD; Zeeman Institute for Systems Biology and Infectious Disease Epidemiology Research, Coventry, United Kingdom.; School of Life Sciences, University of Warwick, Coventry, United Kingdom.; Mathematics Institute, University of Warwick, Coventry, United Kingdom.
Galvani A; Yale School of Public Health, Yale University, New Haven, Connecticut.
Bever C; Institute of Disease Modeling, Bellevue, Washington.
Chitnis N; Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Switzerland.; University of Basel, Switzerland.
Keeling MJ; Zeeman Institute for Systems Biology and Infectious Disease Epidemiology Research, Coventry, United Kingdom.; School of Life Sciences, University of Warwick, Coventry, United Kingdom.; Mathematics Institute, University of Warwick, Coventry, United Kingdom.
Pokaż więcej
Źródło :
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [Clin Infect Dis] 2018 Jun 01; Vol. 66 (suppl_4), pp. S286-S292.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Insect Control*
Models, Theoretical*
Insect Vectors/*parasitology
Trypanosoma brucei gambiense/*isolation & purification
Trypanosomiasis, African/*prevention & control
Tsetse Flies/*parasitology
Animals ; Epidemiological Monitoring ; Humans ; Mass Screening ; Trypanosomiasis, African/diagnosis ; Trypanosomiasis, African/epidemiology ; Trypanosomiasis, African/transmission
Czasopismo naukowe
Tytuł :
Synthesis and antikinetoplastid evaluation of bis(benzyl)spermidine derivatives.
Autorzy :
Jagu E; Institut de Chimie Moléculaire et des Matériaux d'Orsay (ICMMO), CNRS, Univ Paris Sud, Université Paris-Saclay, 15 rue Georges Clemenceau, 91405 Orsay Cedex, France.
Pomel S; Chimiothérapie antiparasitaire, UMR 8076 BioCis, CNRS, Univ Paris Sud, Université Paris-Saclay, 5 rue Jean-Baptiste Clément, 92290 Châtenay-Malabry, France.
Diez-Martinez A; Institut de Chimie Moléculaire et des Matériaux d'Orsay (ICMMO), CNRS, Univ Paris Sud, Université Paris-Saclay, 15 rue Georges Clemenceau, 91405 Orsay Cedex, France.
Rascol E; Institut de Chimie Moléculaire et des Matériaux d'Orsay (ICMMO), CNRS, Univ Paris Sud, Université Paris-Saclay, 15 rue Georges Clemenceau, 91405 Orsay Cedex, France.
Pethe S; Institut de Chimie Moléculaire et des Matériaux d'Orsay (ICMMO), CNRS, Univ Paris Sud, Université Paris-Saclay, 15 rue Georges Clemenceau, 91405 Orsay Cedex, France.
Loiseau PM; Chimiothérapie antiparasitaire, UMR 8076 BioCis, CNRS, Univ Paris Sud, Université Paris-Saclay, 5 rue Jean-Baptiste Clément, 92290 Châtenay-Malabry, France. Electronic address: .
Labruère R; Institut de Chimie Moléculaire et des Matériaux d'Orsay (ICMMO), CNRS, Univ Paris Sud, Université Paris-Saclay, 15 rue Georges Clemenceau, 91405 Orsay Cedex, France. Electronic address: .
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Źródło :
European journal of medicinal chemistry [Eur J Med Chem] 2018 Apr 25; Vol. 150, pp. 655-666. Date of Electronic Publication: 2018 Mar 06.
Typ publikacji :
Journal Article
MeSH Terms :
Antiprotozoal Agents/*pharmacology
Spermidine/*pharmacology
Antiprotozoal Agents/chemical synthesis ; Antiprotozoal Agents/chemistry ; Dose-Response Relationship, Drug ; Leishmania donovani ; Molecular Structure ; Parasitic Sensitivity Tests ; Spermidine/chemical synthesis ; Spermidine/chemistry ; Structure-Activity Relationship ; Trypanosoma brucei gambiense
Czasopismo naukowe
Tytuł :
The impact of passive case detection on the transmission dynamics of gambiense Human African Trypanosomiasis.
Autorzy :
Checchi F; Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Funk S; Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, United Kingdom.; Centre for the Mathematical Modelling of Infectious Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Chandramohan D; Department of Disease Control, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Chappuis F; Division of Tropical and Humanitarian Medicine, Geneva University Hospitals, Geneva, Switzerland.
Haydon DT; Institute of Biodiversity, Animal Health and Comparative Medicine, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom.
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Źródło :
PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2018 Apr 06; Vol. 12 (4), pp. e0006276. Date of Electronic Publication: 2018 Apr 06 (Print Publication: 2018).
Typ publikacji :
Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
MeSH Terms :
Models, Theoretical*
Trypanosomiasis, African/*epidemiology
Trypanosomiasis, African/*transmission
Animals ; Humans ; Incidence ; Likelihood Functions ; Mass Screening ; Sudan/epidemiology ; Trypanosoma brucei gambiense ; Uganda/epidemiology
Czasopismo naukowe
Tytuł :
A single amino acid substitution in the group 1 Trypanosoma brucei gambiense haptoglobin-hemoglobin receptor abolishes TLF-1 binding.
Autorzy :
DeJesus E; Department of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia, USA.
Kieft R
Albright B
Stephens NA
Hajduk SL
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Źródło :
PLoS pathogens [PLoS Pathog] 2013; Vol. 9 (4), pp. e1003317. Date of Electronic Publication: 2013 Apr 18.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Haptoglobins/*genetics
Haptoglobins/*metabolism
Hemoglobins/*genetics
Hemoglobins/*metabolism
Lipoproteins, HDL/*metabolism
Trypanosoma brucei gambiense/*immunology
Trypanosoma brucei rhodesiense/*immunology
Amino Acid Substitution ; Cell Line ; Endocytosis ; Gene Knockout Techniques ; Haptoglobins/chemistry ; Hemoglobins/chemistry ; Humans ; Sequence Alignment ; Trypanosoma brucei gambiense/chemistry ; Trypanosoma brucei gambiense/genetics ; Trypanosoma brucei gambiense/metabolism ; Trypanosoma brucei rhodesiense/genetics ; Trypanosoma brucei rhodesiense/metabolism ; Trypanosomiasis, African/immunology
Czasopismo naukowe
Tytuł :
The TgsGP gene is essential for resistance to human serum in Trypanosoma brucei gambiense.
Autorzy :
Capewell P; Wellcome Centre for Molecular Parasitology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom.
Clucas C
DeJesus E
Kieft R
Hajduk S
Veitch N
Steketee PC
Cooper A
Weir W
MacLeod A
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Źródło :
PLoS pathogens [PLoS Pathog] 2013; Vol. 9 (10), pp. e1003686. Date of Electronic Publication: 2013 Oct 03.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Protozoan Proteins/*metabolism
Trypanosoma brucei gambiense/*metabolism
Trypanosoma brucei gambiense/*pathogenicity
Trypanosomiasis, African/*metabolism
Apolipoprotein L1 ; Apolipoproteins/genetics ; Apolipoproteins/metabolism ; Humans ; Lipoproteins, HDL/genetics ; Lipoproteins, HDL/metabolism ; Protozoan Proteins/genetics ; Trypanosoma brucei gambiense/genetics ; Trypanosomiasis, African/genetics ; Trypanosomiasis, African/pathology
Czasopismo naukowe
Tytuł :
[African trypanosomes have the sense of sacrifice].
Autorzy :
Pays E
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Transliterated Title :
Les trypanosomes africains ont le sens du sacrifice.
Źródło :
Medecine sciences : M/S [Med Sci (Paris)] 2012 Oct; Vol. 28 (10), pp. 817-9. Date of Electronic Publication: 2012 Oct 12.
Typ publikacji :
Wiadomości
MeSH Terms :
Trypanosoma brucei gambiense/*physiology
Trypanosomiasis, African/*immunology
Trypanosomiasis, African/*parasitology
Adenylyl Cyclases/immunology ; Adenylyl Cyclases/metabolism ; Adenylyl Cyclases/physiology ; Animals ; Humans ; Immune System/physiology ; Models, Biological ; Trypanosoma brucei gambiense/immunology ; Trypanosoma brucei gambiense/pathogenicity ; Variant Surface Glycoproteins, Trypanosoma/immunology ; Variant Surface Glycoproteins, Trypanosoma/physiology
Periodyk
Tytuł :
Tackling imported tropical diseases in China.
Autorzy :
Zhou XN; Key Laboratory on Biology of Parasite and Vector, Ministry of Health, Shanghai, 200025, China. .; National Center for International Research on Tropical Diseases, Shanghai, 200025, China. .; WHO Collaborating Center for Tropical Diseases, Shanghai, 200025, China. .; National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Shanghai, 200025, China. .
Qian MB; Key Laboratory on Biology of Parasite and Vector, Ministry of Health, Shanghai, 200025, China.; National Center for International Research on Tropical Diseases, Shanghai, 200025, China.; WHO Collaborating Center for Tropical Diseases, Shanghai, 200025, China.; National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Shanghai, 200025, China.
Priotto G; Department of Control of Neglected Tropical Diseases, World Health Organization, Geneva, 1211, Switzerland.
Franco JR; Department of Control of Neglected Tropical Diseases, World Health Organization, Geneva, 1211, Switzerland.
Guo JG; Department of Control of Neglected Tropical Diseases, World Health Organization, Geneva, 1211, Switzerland.
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Źródło :
Emerging microbes & infections [Emerg Microbes Infect] 2018 Feb 07; Vol. 7 (1), pp. 12. Date of Electronic Publication: 2018 Feb 07.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Travel*
Communicable Diseases, Imported/*epidemiology
China/epidemiology ; Communicable Diseases, Imported/parasitology ; Humans ; Tanzania/epidemiology ; Trypanosoma brucei gambiense/isolation & purification ; Trypanosomiasis, African/diagnosis ; Trypanosomiasis, African/drug therapy ; Trypanosomiasis, African/epidemiology ; Trypanosomiasis, African/parasitology
Czasopismo naukowe

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