Wszystkie pola: "Trypanosomiasis, African" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Consistent detection of Trypanosoma brucei but not T. congolense DNA in faeces of experimentally infected cattle.
Autorzy:: Saldanha I; Vector Biology Department, Liverpool School of Tropical Medicine, Liverpool, UK. .
Betson M; School of Veterinary Medicine, University of Surrey, Guildford, UK.
Vrettou C; Roslin Institute, University of Edinburgh, Edinburgh, UK.
Paxton E; Roslin Institute, University of Edinburgh, Edinburgh, UK.
Nixon J; Large Animal Research and Imaging Facility, University of Edinburgh, Edinburgh, UK.
Tennant P; Large Animal Research and Imaging Facility, University of Edinburgh, Edinburgh, UK.
Ritchie A; Large Animal Research and Imaging Facility, University of Edinburgh, Edinburgh, UK.
Matthews KR; Institute of Immunology and Infection, University of Edinburgh, Edinburgh, UK.
Morrison LJ; Roslin Institute, University of Edinburgh, Edinburgh, UK.
Torr SJ; Vector Biology Department, Liverpool School of Tropical Medicine, Liverpool, UK.
Cunningham LJ; Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool, UK.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Feb 20; Vol. 14 (1), pp. 4158. Date of Electronic Publication: 2024 Feb 20.
Typ publikacji:: Journal Article
MeSH Terms:: Trypanosoma brucei brucei*/genetics
Trypanosoma congolense*/genetics
Trypanosomiasis, African*/diagnosis
Trypanosomiasis, African*/veterinary
Trypanosomiasis, African*/epidemiology
Trypanosoma*/genetics
Humans ; Cattle ; Animals ; DNA ; Feces

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Skocz do pozycji: 2.

Tytuł:: Performance of diagnostic tests for Trypanosoma brucei brucei in experimentally infected pigs.
Autorzy:: Ilboudo K; Unité de Recherche sur les Maladies à Vecteurs et Biodiversité, Centre International de Recherche-Développement sur l'Elevage en zone Subhumide, Bobo-Dioulasso, Burkina Faso.; Unité de Formation et de Recherche en Sciences de la Vie et de la Terre, Université Nazi Boni, Bobo-Dioulasso, Burkina Faso.
Boulangé A; Unité de Recherche sur les Maladies à Vecteurs et Biodiversité, Centre International de Recherche-Développement sur l'Elevage en zone Subhumide, Bobo-Dioulasso, Burkina Faso.; Unité de Recherche « Trypanosomoses », Institut Pierre Richet, Bouaké, Côte d'Ivoire.; CIRAD, UMR INTERTRYP, Montpellier, France.; INTERTRYP, University of Montpellier, CIRAD, IRD, Montpellier, France.
Hounyèmè RE; Unité de Recherche sur les Maladies à Vecteurs et Biodiversité, Centre International de Recherche-Développement sur l'Elevage en zone Subhumide, Bobo-Dioulasso, Burkina Faso.; Unité de Recherche « Trypanosomoses », Institut Pierre Richet, Bouaké, Côte d'Ivoire.
Gimonneau G; CIRAD, UMR INTERTRYP, Montpellier, France.; INTERTRYP, University of Montpellier, CIRAD, IRD, Montpellier, France.; Laboratoire National d'Élevage et de Recherches Vétérinaires, Service de Bio-Écologie et Pathologies Parasitaires, Dakar-Hann, Sénégal.
Kaboré J; Unité de Recherche sur les Maladies à Vecteurs et Biodiversité, Centre International de Recherche-Développement sur l'Elevage en zone Subhumide, Bobo-Dioulasso, Burkina Faso.; Unité de Formation et de Recherche en Sciences de la Vie et de la Terre, Université Nazi Boni, Bobo-Dioulasso, Burkina Faso.
Belem AGM; Institut du Développement Rural, Université Nazi Boni, Bobo-Dioulasso, Burkina Faso.
Desquesnes M; CIRAD, UMR INTERTRYP, Montpellier, France.; INTERTRYP, University of Montpellier, CIRAD, IRD, Montpellier, France.; National Veterinary School of Toulouse (ENVT), Toulouse, France.
Lejon V; INTERTRYP, University of Montpellier, CIRAD, IRD, Montpellier, France.
Koffi M; Laboratoire de Biodiversité et Gestion des Ecosystèmes Tropicaux, Unité de Recherche en Génétique et Épidémiologie Moléculaire, UFR Environnement, Université Jean Lorougnon Guédé, Daloa, Côte d'Ivoire.
Jamonneau V; Unité de Recherche « Trypanosomoses », Institut Pierre Richet, Bouaké, Côte d'Ivoire.; INTERTRYP, University of Montpellier, CIRAD, IRD, Montpellier, France.
Thévenon S; CIRAD, UMR INTERTRYP, Montpellier, France.; INTERTRYP, University of Montpellier, CIRAD, IRD, Montpellier, France.; Pokaż więcej
Źródło:: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2023 Nov 09; Vol. 17 (11), pp. e0011730. Date of Electronic Publication: 2023 Nov 09 (Print Publication: 2023).
Typ publikacji:: Journal Article
MeSH Terms:: Trypanosoma brucei brucei*
Trypanosomiasis, African*/diagnosis
Trypanosomiasis, African*/veterinary
Trypanosomiasis, African*/parasitology
Trypanosoma*
Humans ; Animals ; Swine ; Livestock ; Diagnostic Tests, Routine ; Sensitivity and Specificity

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Skocz do pozycji: 3.

Tytuł:: Spatial confinement of Trypanosoma brucei in microfluidic traps provides a new tool to study free swimming parasites.
Autorzy:: De Niz M; Trypanosome Cell Biology Unit, Department of Parasites and Insect Vectors, Institut Pasteur, Université de Paris, INSERM U1201, Paris, France.
Frachon E; Institut Pasteur, Université de Paris, Biomaterials and Microfluidics Core Facility, Paris, France.
Gobaa S; Institut Pasteur, Université de Paris, Biomaterials and Microfluidics Core Facility, Paris, France.
Bastin P; Trypanosome Cell Biology Unit, Department of Parasites and Insect Vectors, Institut Pasteur, Université de Paris, INSERM U1201, Paris, France.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2023 Dec 22; Vol. 18 (12), pp. e0296257. Date of Electronic Publication: 2023 Dec 22 (Print Publication: 2023).
Typ publikacji:: Journal Article
MeSH Terms:: Trypanosoma brucei brucei*
Parasites*
Trypanosomiasis, African*
Tsetse Flies*/parasitology
Animals ; Microfluidics ; Swimming

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Skocz do pozycji: 4.

Tytuł:: FLAgellum Member 8 modulates extravascular distribution of African trypanosomes.
Autorzy:: Calvo-Alvarez E; Trypanosome Transmission Group, Trypanosome Cell Biology Unit, INSERM U1201, Department of Parasites and Insect Vectors, Institut Pasteur, Université Paris Cité, Paris, France.
Ngoune JMT; Trypanosome Transmission Group, Trypanosome Cell Biology Unit, INSERM U1201, Department of Parasites and Insect Vectors, Institut Pasteur, Université Paris Cité, Paris, France.
Sharma P; Trypanosome Transmission Group, Trypanosome Cell Biology Unit, INSERM U1201, Department of Parasites and Insect Vectors, Institut Pasteur, Université Paris Cité, Paris, France.; Sorbonne Université, ED515 Complexité du Vivant, Paris, France.
Cooper A; Wellcome Centre for Integrative Parasitology, College of Medical, Veterinary, and Life Sciences, Henry Wellcome Building for Comparative Medical Sciences, Glasgow, Scotland, United Kingdom.
Camara A; Parasitology Unit, Institut Pasteur of Guinea, Conakry, Guinea.
Travaillé C; Trypanosome Transmission Group, Trypanosome Cell Biology Unit, INSERM U1201, Department of Parasites and Insect Vectors, Institut Pasteur, Université Paris Cité, Paris, France.; Photonic BioImaging (UTechS PBI), Institut Pasteur, Université Paris Cité, Paris, France.
Crouzols A; Trypanosome Transmission Group, Trypanosome Cell Biology Unit, INSERM U1201, Department of Parasites and Insect Vectors, Institut Pasteur, Université Paris Cité, Paris, France.
MacLeod A; Wellcome Centre for Integrative Parasitology, College of Medical, Veterinary, and Life Sciences, Henry Wellcome Building for Comparative Medical Sciences, Glasgow, Scotland, United Kingdom.
Rotureau B; Trypanosome Transmission Group, Trypanosome Cell Biology Unit, INSERM U1201, Department of Parasites and Insect Vectors, Institut Pasteur, Université Paris Cité, Paris, France.; Parasitology Unit, Institut Pasteur of Guinea, Conakry, Guinea.; Pokaż więcej
Źródło:: PLoS pathogens [PLoS Pathog] 2023 Dec 21; Vol. 19 (12), pp. e1011220. Date of Electronic Publication: 2023 Dec 21 (Print Publication: 2023).
Typ publikacji:: Journal Article
MeSH Terms:: Trypanosoma brucei brucei*/metabolism
Trypanosomiasis, African*/parasitology
Animals ; Protozoan Proteins/genetics ; Protozoan Proteins/metabolism ; Signal Transduction ; Cell Communication ; Mammals ; Flagella/metabolism

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Skocz do pozycji: 5.

Tytuł:: Adaptation of CUT&RUN for use in African trypanosomes.
Autorzy:: Miller G; Harvey Mudd College, Claremont, CA, United States of America.
Rollosson LM; Harvey Mudd College, Claremont, CA, United States of America.
Saada C; Harvey Mudd College, Claremont, CA, United States of America.
Wade SJ; Harvey Mudd College, Claremont, CA, United States of America.
Schulz D; Harvey Mudd College, Claremont, CA, United States of America.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2023 Nov 21; Vol. 18 (11), pp. e0292784. Date of Electronic Publication: 2023 Nov 21 (Print Publication: 2023).
Typ publikacji:: Journal Article
MeSH Terms:: Trypanosoma*/genetics
Trypanosoma brucei brucei*/metabolism
Trypanosomiasis, African*/parasitology
Animals

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Skocz do pozycji: 6.

Tytuł:: The murine meninges acquire lymphoid tissue properties and harbour autoreactive B cells during chronic Trypanosoma brucei infection.
Autorzy:: Quintana JF; Lydia Becker Institute of Immunology and Inflammation, University of Manchester, United Kingdom.; Division of Immunology, Immunity to Infection and Health, Manchester Academic Health Science Centre, University of Manchester, United Kingdom.; School of Biodiversity, One Health, Veterinary Medicine (SBOHVM), College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow United Kingdom.
Sinton MC; Lydia Becker Institute of Immunology and Inflammation, University of Manchester, United Kingdom.; Division of Cardiovascular Sciences, University of Manchester, United Kingdom.
Chandrasegaran P; School of Biodiversity, One Health, Veterinary Medicine (SBOHVM), College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow United Kingdom.
Kumar Dubey L; Queen Mary University of London, London, United Kingdom.
Ogunsola J; School of Biodiversity, One Health, Veterinary Medicine (SBOHVM), College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow United Kingdom.
Al Samman M; School of Biodiversity, One Health, Veterinary Medicine (SBOHVM), College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow United Kingdom.
Haley M; Lydia Becker Institute of Immunology and Inflammation, University of Manchester, United Kingdom.; Division of Immunology, Immunity to Infection and Health, Manchester Academic Health Science Centre, University of Manchester, United Kingdom.
McConnell G; Strathclyde Institute of Pharmacy and Biomedical Sciences (SIPBS), University of Strathclyde, Glasgow, United Kingdom.
Kuispond Swar NR; Department of Parasitology, National Institute of Biomedical Research, Kinshasa, Democratic Republic of the Congo.
Ngoyi DM; Department of Parasitology, National Institute of Biomedical Research, Kinshasa, Democratic Republic of the Congo.
Bending D; Institute of Immunology and Immunotherapy, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom.
de Lecea L; Stanford University School of Medicine, Stanford, California, United States of America.
MacLeod A; School of Biodiversity, One Health, Veterinary Medicine (SBOHVM), College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow United Kingdom.
Mabbott NA; The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, United Kingdom.; Pokaż więcej
Źródło:: PLoS biology [PLoS Biol] 2023 Nov 20; Vol. 21 (11), pp. e3002389. Date of Electronic Publication: 2023 Nov 20 (Print Publication: 2023).
Typ publikacji:: Journal Article
MeSH Terms:: Trypanosoma brucei brucei*
Trypanosomiasis, African*
Humans ; Animals ; Mice ; Persistent Infection ; Meninges/metabolism ; Lymphoid Tissue/metabolism ; Autoantibodies

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Skocz do pozycji: 7.

Tytuł:: In Silico and In Vitro Search for Dual Inhibitors of the Trypanosoma brucei and Leishmania major Pteridine Reductase 1 and Dihydrofolate Reductase.
Autorzy:: Possart K; University of Muenster, Institute for Pharmaceutical Biology and Phytochemistry (IPBP), PharmaCampus, Corrensstrasse 48, D-48149 Muenster, Germany.
Herrmann FC; University of Muenster, Institute for Pharmaceutical Biology and Phytochemistry (IPBP), PharmaCampus, Corrensstrasse 48, D-48149 Muenster, Germany.
Jose J; University of Muenster, Institute of Pharmaceutical and Medicinal Chemistry, PharmaCampus, Corrensstrasse 48, D-48149 Muenster, Germany.
Schmidt TJ; University of Muenster, Institute for Pharmaceutical Biology and Phytochemistry (IPBP), PharmaCampus, Corrensstrasse 48, D-48149 Muenster, Germany.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2023 Nov 10; Vol. 28 (22). Date of Electronic Publication: 2023 Nov 10.
Typ publikacji:: Journal Article
MeSH Terms:: Leishmania major*
Trypanosoma brucei brucei*
Trypanosomiasis, African*/drug therapy
Humans ; Animals ; Tetrahydrofolate Dehydrogenase/metabolism ; Pteridines/chemistry

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Skocz do pozycji: 8.

Tytuł:: Tackling Sleeping Sickness: Current and Promising Therapeutics and Treatment Strategies.
Autorzy:: Jamabo M; Biotechnology Innovation Centre, Rhodes University, Makhanda 6139, South Africa.
Mahlalela M; Biotechnology Innovation Centre, Rhodes University, Makhanda 6139, South Africa.
Edkins AL; Department of Biochemistry and Microbiology, Biomedical Biotechnology Research Centre (BioBRU), Rhodes University, Makhanda 6139, South Africa.
Boshoff A; Biotechnology Innovation Centre, Rhodes University, Makhanda 6139, South Africa.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Aug 07; Vol. 24 (15). Date of Electronic Publication: 2023 Aug 07.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Trypanosomiasis, African*/diagnosis
Trypanosomiasis, African*/drug therapy
COVID-19*/epidemiology
Trypanosoma brucei brucei*/metabolism
Trypanosoma*
Animals ; Humans ; Pandemics

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Skocz do pozycji: 9.

Tytuł:: Health economic evaluation of strategies to eliminate gambiense human African trypanosomiasis in the Mandoul disease focus of Chad.
Autorzy:: Antillon M; Swiss Tropical and Public Health Institute, Basel, Switzerland.; University of Basel, Basel, Switzerland.
Huang CI; Zeeman Institute for Systems Biology and Infectious Disease Epidemiology Research, The University of Warwick, Coventry, United Kingdom.; Mathematics Institute, The University of Warwick, Coventry, United Kingdom.
Sutherland SA; Zeeman Institute for Systems Biology and Infectious Disease Epidemiology Research, The University of Warwick, Coventry, United Kingdom.; Warwick Medical School, University of Warwick, Coventry, United Kingdom.
Crump RE; Zeeman Institute for Systems Biology and Infectious Disease Epidemiology Research, The University of Warwick, Coventry, United Kingdom.; Mathematics Institute, The University of Warwick, Coventry, United Kingdom.
Bessell PR; Independent Consultant, Edinburgh, United Kingdom.
Shaw APM; Infection Medicine, Deanery of Biomedical Sciences, College of Medicine and Veterinary Medicine, The University of Edinburgh, Edinburgh, United Kingdom.; AP Consultants, Walworth Enterprise Centre, Andover, United Kingdom.
Tirados I; Department of Vector Biology, Liverpool School of Tropical Medicine, United Kingdom.
Picado A; Foundation for Innovative New Diagnostics (FIND), Geneva, Switzerland.
Biéler S; Foundation for Innovative New Diagnostics (FIND), Geneva, Switzerland.
Brown PE; Zeeman Institute for Systems Biology and Infectious Disease Epidemiology Research, The University of Warwick, Coventry, United Kingdom.; Mathematics Institute, The University of Warwick, Coventry, United Kingdom.
Solano P; Institut de Recherche pour le Développement, UMR INTERTRYP IRD-CIRAD, Université de Montpellier, Montpellier, France.
Mbainda S; Programme National de Lutte contre la Trypanosomiase Humaine Africaine (PNLTHA), Moundou, Chad.
Darnas J; Programme National de Lutte contre la Trypanosomiase Humaine Africaine (PNLTHA), Moundou, Chad.
Wang-Steverding X; Zeeman Institute for Systems Biology and Infectious Disease Epidemiology Research, The University of Warwick, Coventry, United Kingdom.; Warwick Medical School, University of Warwick, Coventry, United Kingdom.
Crowley EH; Zeeman Institute for Systems Biology and Infectious Disease Epidemiology Research, The University of Warwick, Coventry, United Kingdom.; Mathematics Institute, The University of Warwick, Coventry, United Kingdom.
Peka M; Programme National de Lutte contre la Trypanosomiase Humaine Africaine (PNLTHA), Moundou, Chad.
Tediosi F; Swiss Tropical and Public Health Institute, Basel, Switzerland.; University of Basel, Basel, Switzerland.
Rock KS; Zeeman Institute for Systems Biology and Infectious Disease Epidemiology Research, The University of Warwick, Coventry, United Kingdom.; Mathematics Institute, The University of Warwick, Coventry, United Kingdom.; Pokaż więcej
Źródło:: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2023 Jul 27; Vol. 17 (7), pp. e0011396. Date of Electronic Publication: 2023 Jul 27 (Print Publication: 2023).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Trypanosomiasis, African*/diagnosis
Trypanosomiasis, African*/epidemiology
Trypanosomiasis, African*/prevention & control
Trypanosoma brucei brucei*
Animals ; Humans ; Chad/epidemiology ; Cost-Benefit Analysis ; Trypanosoma brucei gambiense

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Skocz do pozycji: 10.

Tytuł:: Vector competence of sterile male Glossina fuscipes fuscipes for Trypanosoma brucei brucei: implications for the implementation of the sterile insect technique in a sleeping sickness focus in Chad.
Autorzy:: Mahamat MH; Institut de Recherche en Elevage pour le Développement (IRED), Ndjaména, Chad.
Ségard A; Université de Montpellier, Cirad, IRD, Intertryp, Montpellier, France.
Rayaisse JB; Centre International de Recherche-Développement sur l'Elevage en Zone Subhumide (CIRDES), Bobo-Dioulasso, Burkina Faso.
Argiles-Herrero R; Joint Food and Agriculture Organization of the United Nations/International Atomic Energy Agency Centre of Nuclear Techniques in Food and Agriculture, Insect Pest Control Sub-programme, A-1400, Vienna, Austria.
Parker AG; Joint Food and Agriculture Organization of the United Nations/International Atomic Energy Agency Centre of Nuclear Techniques in Food and Agriculture, Insect Pest Control Sub-programme, A-1400, Vienna, Austria.
Solano P; Université de Montpellier, Cirad, IRD, Intertryp, Montpellier, France.
Abd-Alla AMM; Joint Food and Agriculture Organization of the United Nations/International Atomic Energy Agency Centre of Nuclear Techniques in Food and Agriculture, Insect Pest Control Sub-programme, A-1400, Vienna, Austria.
Bouyer J; Joint Food and Agriculture Organization of the United Nations/International Atomic Energy Agency Centre of Nuclear Techniques in Food and Agriculture, Insect Pest Control Sub-programme, A-1400, Vienna, Austria.; Université de Montpellier, Cirad, INRAE, ASTRE, Montpellier, France.
Ravel S; Université de Montpellier, Cirad, IRD, Intertryp, Montpellier, France. .; Pokaż więcej
Źródło:: Parasites & vectors [Parasit Vectors] 2023 Mar 22; Vol. 16 (1), pp. 111. Date of Electronic Publication: 2023 Mar 22.
Typ publikacji:: Journal Article
MeSH Terms:: Trypanosomiasis, African*/epidemiology
Trypanosomiasis, African*/prevention & control
Trypanosomiasis, African*/parasitology
Tsetse Flies*/parasitology
Trypanosoma brucei brucei*
Trypanocidal Agents*
Trypanosoma*
Infertility, Male*
Animals ; Male ; Humans ; Chad/epidemiology ; Insecta

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Skocz do pozycji: 11.

Tytuł:: Structural similarities between the metacyclic and bloodstream form variant surface glycoproteins of the African trypanosome.
Autorzy:: Chandra M; Division of Structural Biology of Infection and Immunity, German Cancer Research Center, Heidelberg, Germany.; Division of Immune Diversity, German Cancer Research Center, Heidelberg, Germany.
Đaković S; Division of Structural Biology of Infection and Immunity, German Cancer Research Center, Heidelberg, Germany.
Foti K; Division of Structural Biology of Infection and Immunity, German Cancer Research Center, Heidelberg, Germany.
Zeelen JP; Division of Structural Biology of Infection and Immunity, German Cancer Research Center, Heidelberg, Germany.
van Straaten M; Division of Structural Biology of Infection and Immunity, German Cancer Research Center, Heidelberg, Germany.
Aresta-Branco F; Division of Structural Biology of Infection and Immunity, German Cancer Research Center, Heidelberg, Germany.; Division of Immune Diversity, German Cancer Research Center, Heidelberg, Germany.
Tihon E; Institut Pasteur, Université Paris Cité, Trypanosome Molecular Biology, Department of Parasites and Insect Vectors, Paris, France.
Lübbehusen N; Centre for Molecular Biology at the University of Heidelberg (ZMBH), DKFZ-ZMBH Alliance, Heidelberg, Germany.
Ruppert T; Centre for Molecular Biology at the University of Heidelberg (ZMBH), DKFZ-ZMBH Alliance, Heidelberg, Germany.
Glover L; Institut Pasteur, Université Paris Cité, Trypanosome Molecular Biology, Department of Parasites and Insect Vectors, Paris, France.
Papavasiliou FN; Division of Immune Diversity, German Cancer Research Center, Heidelberg, Germany.
Stebbins CE; Division of Structural Biology of Infection and Immunity, German Cancer Research Center, Heidelberg, Germany.; Pokaż więcej
Źródło:: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2023 Feb 13; Vol. 17 (2), pp. e0011093. Date of Electronic Publication: 2023 Feb 13 (Print Publication: 2023).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Trypanosoma brucei brucei*/genetics
Trypanosoma*
Tsetse Flies*/parasitology
Trypanosomiasis, African*/parasitology
Animals ; Membrane Glycoproteins/metabolism ; Variant Surface Glycoproteins, Trypanosoma/genetics ; Mammals

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Skocz do pozycji: 12.

Tytuł:: Drugging the Undruggable Trypanosoma brucei Monothiol Glutaredoxin 1.
Autorzy:: Favaro A; Molecular Modeling Section (MMS), Department of Pharmaceutical and Pharmacological Sciences, University of Padova, via Marzolo 5, 35131 Padova, Italy.
Bolcato G; Molecular Modeling Section (MMS), Department of Pharmaceutical and Pharmacological Sciences, University of Padova, via Marzolo 5, 35131 Padova, Italy.
Comini MA; Laboratory Redox Biology of Trypanosomes, Institut Pasteur de Montevideo, Mataojo 2020, Montevideo 11400, Uruguay.
Moro S; Molecular Modeling Section (MMS), Department of Pharmaceutical and Pharmacological Sciences, University of Padova, via Marzolo 5, 35131 Padova, Italy.
Bellanda M; Department of Chemical Sciences, University of Padova, via Marzolo 1, 35131 Padova, Italy.; Consiglio Nazionale delle Ricerche, Institute of Biomolecular Chemistry, 35131 Padova, Italy.
Sturlese M; Molecular Modeling Section (MMS), Department of Pharmaceutical and Pharmacological Sciences, University of Padova, via Marzolo 5, 35131 Padova, Italy.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2023 Jan 28; Vol. 28 (3). Date of Electronic Publication: 2023 Jan 28.
Typ publikacji:: Journal Article
MeSH Terms:: Trypanosoma brucei brucei*/metabolism
Trypanosoma*/metabolism
Trypanosomiasis, African*/drug therapy
Humans ; Female ; Animals ; Cattle ; Horses ; Glutaredoxins/chemistry ; Glutathione/metabolism

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Skocz do pozycji: 13.

Tytuł:: The Activity of Red Nigerian Propolis and Some of Its Components against Trypanosoma brucei and Trypanosoma congolense .
Autorzy:: Alenezi SS; Strathclyde Institute of Pharmacy and Biomedical Science, University of Strathclyde, 161 Cathedral Street, Glasgow G4 0RE, UK.
Alenezi ND; Strathclyde Institute of Pharmacy and Biomedical Science, University of Strathclyde, 161 Cathedral Street, Glasgow G4 0RE, UK.
Ebiloma GU; Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8TA, UK.; School of Health and Life Sciences, Teesside University, Middlesbrough TS1 3BX, UK.
Natto MJ; Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8TA, UK.
Ungogo MA; Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8TA, UK.; Department of Veterinary Pharmacology and Toxicology, Faculty of Veterinary Medicine, Ahmadu Bello University, Zaria 810107, Kaduna State, Nigeria.
Igoli JO; Strathclyde Institute of Pharmacy and Biomedical Science, University of Strathclyde, 161 Cathedral Street, Glasgow G4 0RE, UK.; Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8TA, UK.; Department of Chemical Sciences, Pen Resource University, Gombe-Bauchi Road, Gombe 771104, Lafiyawo, Nigeria.
Ferro VA; Strathclyde Institute of Pharmacy and Biomedical Science, University of Strathclyde, 161 Cathedral Street, Glasgow G4 0RE, UK.
Gray AI; Strathclyde Institute of Pharmacy and Biomedical Science, University of Strathclyde, 161 Cathedral Street, Glasgow G4 0RE, UK.
Fearnley J; BeeVital, Whitby YO22 5JR, North Yorkshire, UK.
Koning HP; Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8TA, UK.
Watson DG; Strathclyde Institute of Pharmacy and Biomedical Science, University of Strathclyde, 161 Cathedral Street, Glasgow G4 0RE, UK.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2023 Jan 07; Vol. 28 (2). Date of Electronic Publication: 2023 Jan 07.
Typ publikacji:: Journal Article
MeSH Terms:: Trypanosoma brucei brucei*
Trypanosoma congolense*
Propolis*/pharmacology
Propolis*/chemistry
Anti-Infective Agents*
Trypanosomiasis, African*/drug therapy
Humans ; Animals ; Nigeria

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Skocz do pozycji: 14.

Tytuł:: Clinically relevant benzoxaboroles inhibit mRNA processing in Trypanosoma brucei.
Autorzy:: Waithaka A; Heidelberg University Centre for Molecular Biology (ZMBH), Im Neuenheimer Feld 282, D69120, Heidelberg, Germany.
Clayton C; Heidelberg University Centre for Molecular Biology (ZMBH), Im Neuenheimer Feld 282, D69120, Heidelberg, Germany. .; Pokaż więcej
Źródło:: BMC research notes [BMC Res Notes] 2022 Dec 17; Vol. 15 (1), pp. 371. Date of Electronic Publication: 2022 Dec 17.
Typ publikacji:: Journal Article
MeSH Terms:: Trypanosoma brucei brucei*/genetics
Trypanosomiasis, African*
Humans ; Cattle ; Animals ; Boron Compounds/metabolism ; Boron Compounds/pharmacology ; RNA, Messenger/genetics ; RNA, Messenger/metabolism

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Skocz do pozycji: 15.

Tytuł:: Pseudokinase NRP1 facilitates endocytosis of transferrin in the African trypanosome.
Autorzy:: Kumar G; Department of Molecular and Cellular Biology, Kennesaw State University, Kennesaw, Georgia.
Thomas B; Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, Georgia.
Mensa-Wilmot K; Department of Molecular and Cellular Biology, Kennesaw State University, Kennesaw, Georgia. .; Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, Georgia. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2022 Nov 03; Vol. 12 (1), pp. 18572. Date of Electronic Publication: 2022 Nov 03.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: Trypanosoma*/metabolism
Trypanosoma brucei brucei*/metabolism
Trypanosomiasis, African*/parasitology
Animals ; Cattle ; Humans ; Endocytosis/genetics ; Endosomes/metabolism ; NIMA-Related Kinases/metabolism ; Protein Kinases/metabolism ; Receptors, Transferrin/metabolism ; Transferrin/genetics ; Transferrin/metabolism ; Neuropilin-1/metabolism

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Skocz do pozycji: 16.

Tytuł:: 2-(Nitroaryl)-5-Substituted-1,3,4-Thiadiazole Derivatives with Antiprotozoal Activities: In Vitro and In Vivo Study.
Autorzy:: Mousavi A; Department of Medicinal Chemistry, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran 1417614411, Iran.
Foroumadi P; Department of Medicinal Chemistry, School of Pharmacy, International Campus, Tehran University of Medical Sciences, Tehran 1417614411, Iran.
Emamgholipour Z; Department of Medicinal Chemistry, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran 1417614411, Iran.
Mäser P; Swiss Tropical and Public Health Institute, 4123 Allschwil, Switzerland.; Faculty of Science, University of Basel, 4002 Basel, Switzerland.
Kaiser M; Swiss Tropical and Public Health Institute, 4123 Allschwil, Switzerland.; Faculty of Science, University of Basel, 4002 Basel, Switzerland.
Foroumadi A; Department of Medicinal Chemistry, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran 1417614411, Iran.; Drug Design and Development Research Center, The Institute of Pharmaceutical Sciences (TIPS), Tehran University of Medical Sciences, Tehran 1417614411, Iran.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2022 Aug 29; Vol. 27 (17). Date of Electronic Publication: 2022 Aug 29.
Typ publikacji:: Journal Article
MeSH Terms:: Antiprotozoal Agents*/pharmacology
Antiprotozoal Agents*/therapeutic use
Chagas Disease*/drug therapy
Trypanocidal Agents*/pharmacology
Trypanosoma brucei brucei*
Trypanosomiasis, African*/drug therapy
Trypanosomiasis, African*/parasitology
Animals ; Mice ; Neglected Diseases/drug therapy ; Nitro Compounds ; Thiadiazoles ; Trypanosoma brucei rhodesiense

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Skocz do pozycji: 17.

Tytuł:: Preliminary Structure-Activity Relationship Study of the MMV Pathogen Box Compound MMV675968 (2,4-Diaminoquinazoline) Unveils Novel Inhibitors of Trypanosoma brucei brucei .
Autorzy:: Dize D; Antimicrobial and Biocontrol Agents Unit (AmBcAU), Laboratory for Phytobiochemistry and Medicinal Plants Studies, Department of Biochemistry, Faculty of Science, University of Yaoundé I, Yaoundé P.O. Box 812, Cameroon.
Tata RB; Research Unit in Bioinformatics (RUBi), Department of Biochemistry and Microbiology, Rhodes University, Grahamstown 6139, South Africa.
Keumoe R; Antimicrobial and Biocontrol Agents Unit (AmBcAU), Laboratory for Phytobiochemistry and Medicinal Plants Studies, Department of Biochemistry, Faculty of Science, University of Yaoundé I, Yaoundé P.O. Box 812, Cameroon.
Kouipou Toghueo RM; Antimicrobial and Biocontrol Agents Unit (AmBcAU), Laboratory for Phytobiochemistry and Medicinal Plants Studies, Department of Biochemistry, Faculty of Science, University of Yaoundé I, Yaoundé P.O. Box 812, Cameroon.
Tchatat MB; Antimicrobial and Biocontrol Agents Unit (AmBcAU), Laboratory for Phytobiochemistry and Medicinal Plants Studies, Department of Biochemistry, Faculty of Science, University of Yaoundé I, Yaoundé P.O. Box 812, Cameroon.
Njanpa CN; Antimicrobial and Biocontrol Agents Unit (AmBcAU), Laboratory for Phytobiochemistry and Medicinal Plants Studies, Department of Biochemistry, Faculty of Science, University of Yaoundé I, Yaoundé P.O. Box 812, Cameroon.
Tchuenguia VC; Antimicrobial and Biocontrol Agents Unit (AmBcAU), Laboratory for Phytobiochemistry and Medicinal Plants Studies, Department of Biochemistry, Faculty of Science, University of Yaoundé I, Yaoundé P.O. Box 812, Cameroon.
Yamthe LT; Antimicrobial and Biocontrol Agents Unit (AmBcAU), Laboratory for Phytobiochemistry and Medicinal Plants Studies, Department of Biochemistry, Faculty of Science, University of Yaoundé I, Yaoundé P.O. Box 812, Cameroon.
Fokou PVT; Antimicrobial and Biocontrol Agents Unit (AmBcAU), Laboratory for Phytobiochemistry and Medicinal Plants Studies, Department of Biochemistry, Faculty of Science, University of Yaoundé I, Yaoundé P.O. Box 812, Cameroon.
Laleu B; Medicines for Malaria Venture, Route de Pré-Bois 20, 1215 Meyrin, Switzerland.
Duffy J; Medicines for Malaria Venture, Route de Pré-Bois 20, 1215 Meyrin, Switzerland.
Bishop OT; Research Unit in Bioinformatics (RUBi), Department of Biochemistry and Microbiology, Rhodes University, Grahamstown 6139, South Africa.
Boyom FF; Antimicrobial and Biocontrol Agents Unit (AmBcAU), Laboratory for Phytobiochemistry and Medicinal Plants Studies, Department of Biochemistry, Faculty of Science, University of Yaoundé I, Yaoundé P.O. Box 812, Cameroon.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2022 Oct 04; Vol. 27 (19). Date of Electronic Publication: 2022 Oct 04.
Typ publikacji:: Journal Article
MeSH Terms:: Trypanocidal Agents*/chemistry
Trypanosoma*/metabolism
Trypanosoma brucei brucei*
Trypanosomiasis, African*/drug therapy
Animals ; Humans ; Iron/therapeutic use ; Ligands ; Quinazolines ; Structure-Activity Relationship ; Tetrahydrofolate Dehydrogenase/metabolism

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Skocz do pozycji: 18.

Tytuł:: Steroidal Antimetabolites Protect Mice against Trypanosoma brucei .
Autorzy:: Chaudhuri M; Department of Microbiology, Immunology, and Physiology, Meharry Medical College, Nashville, TN 37208, USA.
Singha UK; Department of Microbiology, Immunology, and Physiology, Meharry Medical College, Nashville, TN 37208, USA.
Vanderloop BH; Department of Chemistry & Biochemistry, Texas Tech University, Lubbock, TX 79409, USA.
Tripathi A; Department of Microbiology, Immunology, and Physiology, Meharry Medical College, Nashville, TN 37208, USA.
Nes WD; Department of Chemistry & Biochemistry, Texas Tech University, Lubbock, TX 79409, USA.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2022 Jun 25; Vol. 27 (13). Date of Electronic Publication: 2022 Jun 25.
Typ publikacji:: Journal Article
MeSH Terms:: Trypanosoma brucei brucei*
Trypanosomiasis, African*/drug therapy
Trypanosomiasis, African*/prevention & control
Animals ; Antimetabolites/metabolism ; Antimetabolites/pharmacology ; Ergosterol ; Humans ; Mice ; Steroids/pharmacology ; Sterols/metabolism ; Sterols/pharmacology

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Skocz do pozycji: 19.

Tytuł:: Fragment-Based Drug Discovery for Trypanosoma brucei Glycosylphosphatidylinositol-Specific Phospholipase C through Biochemical and WaterLOGSY-NMR Methods.
Autorzy:: Ibrahim MA; Biomedical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Ibaraki 3058566, Japan and.; Department of Biochemistry, Ahmadu Bello University, Zaria, Kaduna 800001, Nigeria.
Yamasaki T; Biomedical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Ibaraki 3058566, Japan and.; Health and Medical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Ibaraki 3058566, Japan.
Furukawa K; Health and Medical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Ibaraki 3058566, Japan.
Yamasaki K; Biomedical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Ibaraki 3058566, Japan and.; Pokaż więcej
Źródło:: Journal of biochemistry [J Biochem] 2022 May 27; Vol. 171 (6), pp. 619-629.
Typ publikacji:: Journal Article
MeSH Terms:: Trypanosoma brucei brucei*/metabolism
Trypanosomiasis, African*/drug therapy
Trypanosomiasis, African*/parasitology
Animals ; Drug Discovery ; Glycosylphosphatidylinositol Diacylglycerol-Lyase/metabolism ; Ligands ; Molecular Docking Simulation ; Spectrum Analysis ; Type C Phospholipases/metabolism ; Water

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Skocz do pozycji: 20.

Tytuł:: Development of Reduced Peptide Bond Pseudopeptide Michael Acceptors for the Treatment of Human African Trypanosomiasis.
Autorzy:: Previti S; Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale Stagno d'Alcontres 31, 98166 Messina, Italy.
Ettari R; Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale Stagno d'Alcontres 31, 98166 Messina, Italy.
Di Chio C; Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale Stagno d'Alcontres 31, 98166 Messina, Italy.; Department of Clinical and Experimental Medicine, University of Messina, Via C. Valeria, 98125 Messina, Italy.
Ravichandran R; DiSTABiF, University of Campania Luigi Vanvitelli, Via Vivaldi 43, 81100 Caserta, Italy.
Bogacz M; Institute of Organic Chemistry & Macromolecular Chemistry, Friedrich-Schiller-University of Jena, Humboldtstraße 10, 07743 Jena, Germany.
Hellmich UA; Institute of Organic Chemistry & Macromolecular Chemistry, Friedrich-Schiller-University of Jena, Humboldtstraße 10, 07743 Jena, Germany.; Centre for Biomolecular Magnetic Resonance (BMRZ), Goethe University Frankfurt, Max von Laue Str. 9, 60438 Frankfurt, Germany.
Schirmeister T; Institute of Pharmaceutical and Biomedical Sciences, University of Mainz, Staudingerweg 5, 55128 Mainz, Germany.
Cosconati S; DiSTABiF, University of Campania Luigi Vanvitelli, Via Vivaldi 43, 81100 Caserta, Italy.
Zappalà M; Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale Stagno d'Alcontres 31, 98166 Messina, Italy.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2022 Jun 11; Vol. 27 (12). Date of Electronic Publication: 2022 Jun 11.
Typ publikacji:: Journal Article
MeSH Terms:: Trypanocidal Agents*/chemistry
Trypanosoma brucei brucei*
Trypanosomiasis, African*/drug therapy
Africa, Northern ; Animals ; Cysteine Proteinase Inhibitors/chemistry ; Humans ; Mammals

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