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Wyszukujesz frazę ""Trypanosomiasis, African"" wg kryterium: Temat


Tytuł :
Fast acting allosteric phosphofructokinase inhibitors block trypanosome glycolysis and cure acute African trypanosomiasis in mice.
Autorzy :
McNae IW; Wellcome Centre for Cell Biology, School of Biological Sciences, University of Edinburgh, Michael Swann Building, Max Born Crescent, Edinburgh, UK.
Kinkead J; Wellcome Centre for Cell Biology, School of Biological Sciences, University of Edinburgh, Michael Swann Building, Max Born Crescent, Edinburgh, UK.
Malik D; Wellcome Centre for Cell Biology, School of Biological Sciences, University of Edinburgh, Michael Swann Building, Max Born Crescent, Edinburgh, UK.
Yen LH; Wellcome Centre for Cell Biology, School of Biological Sciences, University of Edinburgh, Michael Swann Building, Max Born Crescent, Edinburgh, UK.
Walker MK; Selcia Ltd., Fyfield Business and Research Park, Fyfield Road, Ongar, Essex, UK.
Swain C; Cambridge MedChem Consulting, Cambridge, UK.
Webster SP; Centre for Cardiovascular Science, College of Medicine and Veterinary Medicine, University of Edinburgh, Edinburgh, UK.
Gray N; Wellcome Centre for Cell Biology, School of Biological Sciences, University of Edinburgh, Michael Swann Building, Max Born Crescent, Edinburgh, UK.
Fernandes PM; Wellcome Centre for Cell Biology, School of Biological Sciences, University of Edinburgh, Michael Swann Building, Max Born Crescent, Edinburgh, UK.
Myburgh E; York Biomedical Research Institute, Hull York Medical School, University of York, York, UK.
Blackburn EA; Wellcome Centre for Cell Biology, School of Biological Sciences, University of Edinburgh, Michael Swann Building, Max Born Crescent, Edinburgh, UK.
Ritchie R; Institute of Infection Immunity and Inflammation, College of Medical Veterinary Life-Sciences, University of Glasgow, Glasgow, UK.
Austin C; Selcia Ltd., Fyfield Business and Research Park, Fyfield Road, Ongar, Essex, UK.
Wear MA; Wellcome Centre for Cell Biology, School of Biological Sciences, University of Edinburgh, Michael Swann Building, Max Born Crescent, Edinburgh, UK.
Highton AJ; Selcia Ltd., Fyfield Business and Research Park, Fyfield Road, Ongar, Essex, UK.
Keats AJ; Selcia Ltd., Fyfield Business and Research Park, Fyfield Road, Ongar, Essex, UK.
Vong A; Selcia Ltd., Fyfield Business and Research Park, Fyfield Road, Ongar, Essex, UK.
Dornan J; Wellcome Centre for Cell Biology, School of Biological Sciences, University of Edinburgh, Michael Swann Building, Max Born Crescent, Edinburgh, UK.
Mottram JC; York Biomedical Research Institute, Department of Biology, University of York, York, UK.
Michels PAM; Wellcome Centre for Cell Biology, School of Biological Sciences, University of Edinburgh, Michael Swann Building, Max Born Crescent, Edinburgh, UK.
Pettit S; Selcia Ltd., Fyfield Business and Research Park, Fyfield Road, Ongar, Essex, UK. .
Walkinshaw MD; Wellcome Centre for Cell Biology, School of Biological Sciences, University of Edinburgh, Michael Swann Building, Max Born Crescent, Edinburgh, UK. .
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Źródło :
Nature communications [Nat Commun] 2021 Feb 16; Vol. 12 (1), pp. 1052. Date of Electronic Publication: 2021 Feb 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Glycolysis/*drug effects
Phosphofructokinases/*antagonists & inhibitors
Protein Kinase Inhibitors/*pharmacology
Trypanosoma/*enzymology
Trypanosomiasis, African/*metabolism
Trypanosomiasis, African/*parasitology
Acute Disease ; Allosteric Regulation/drug effects ; Animals ; Hep G2 Cells ; Humans ; Inhibitory Concentration 50 ; Kaplan-Meier Estimate ; Mice ; Parasites/drug effects ; Phosphofructokinases/chemistry ; Phosphofructokinases/metabolism ; Protein Binding/drug effects ; Protein Kinase Inhibitors/chemistry ; Protein Kinase Inhibitors/pharmacokinetics ; Protein Kinase Inhibitors/therapeutic use ; Protein Multimerization ; Structure-Activity Relationship ; Trypanosoma/drug effects ; Trypanosomiasis, African/drug therapy
Czasopismo naukowe
Tytuł :
Update on relevant trypanosome peptidases: Validated targets and future challenges.
Autorzy :
Alvarez VE; Instituto de Investigaciones Biotecnológicas 'Dr. Rodolfo Ugalde', Universidad Nacional de San Martín - IIBIO, UNSAM-CONICET, San Martín, B1650HMP Buenos Aires, Argentina. Electronic address: .
Iribarren PA; Instituto de Investigaciones Biotecnológicas 'Dr. Rodolfo Ugalde', Universidad Nacional de San Martín - IIBIO, UNSAM-CONICET, San Martín, B1650HMP Buenos Aires, Argentina.
Niemirowicz GT; Instituto de Investigaciones Biotecnológicas 'Dr. Rodolfo Ugalde', Universidad Nacional de San Martín - IIBIO, UNSAM-CONICET, San Martín, B1650HMP Buenos Aires, Argentina.
Cazzulo JJ; Instituto de Investigaciones Biotecnológicas 'Dr. Rodolfo Ugalde', Universidad Nacional de San Martín - IIBIO, UNSAM-CONICET, San Martín, B1650HMP Buenos Aires, Argentina.
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Źródło :
Biochimica et biophysica acta. Proteins and proteomics [Biochim Biophys Acta Proteins Proteom] 2021 Feb; Vol. 1869 (2), pp. 140577. Date of Electronic Publication: 2020 Nov 30.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Peptide Hydrolases/*genetics
Trypanosoma brucei brucei/*genetics
Trypanosoma cruzi/*genetics
Trypanosomiasis, African/*genetics
Animals ; Cathepsin B/genetics ; Cathepsin B/isolation & purification ; Cattle ; Cysteine Endopeptidases/chemistry ; Cysteine Endopeptidases/therapeutic use ; Cysteine Proteases/genetics ; Cysteine Proteinase Inhibitors/therapeutic use ; Humans ; Protozoan Proteins/chemistry ; Protozoan Proteins/therapeutic use ; Trypanosoma brucei brucei/enzymology ; Trypanosoma brucei brucei/pathogenicity ; Trypanosoma cruzi/enzymology ; Trypanosoma cruzi/pathogenicity ; Trypanosomiasis, African/enzymology ; Trypanosomiasis, African/parasitology
Czasopismo naukowe
Tytuł :
Molecular Diagnosis and Prevalence of Trypanosoma vivax (Trypanosomatida: Trypanosomatidae) in Buffaloes and Ectoparasites in the Brazilian Amazon Region.
Autorzy :
Dyonisio GHS; Programa de Medicina Veterinária e Bem Estar Animal e Saúde Única - Universidade Santo Amaro, Av. Prof. Enéas de Siqueira Neto, São Paulo, SP, Brasil.
Batista HR; Laboratório de Sanidade Animal, Universidade Federal do Oeste do Pará. Rua Vera Cruz s/n, Salé, Santarém, Pará, Brasil.
da Silva RE; Laboratório de Doenças Parasitárias, Departamento de Medicina Veterinária Preventiva e Saúde Animal, Faculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo. Av. Prof. Dr. Orlando Marques de Paiva, Cidade Universitária, São Paulo, SP, Brasil.
Azevedo RCFE; Programa de Medicina Veterinária e Bem Estar Animal e Saúde Única - Universidade Santo Amaro, Av. Prof. Enéas de Siqueira Neto, São Paulo, SP, Brasil.
Costa JOJ; Laboratório de Doenças Parasitárias, Departamento de Medicina Veterinária Preventiva e Saúde Animal, Faculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo. Av. Prof. Dr. Orlando Marques de Paiva, Cidade Universitária, São Paulo, SP, Brasil.
Manhães IBO; Programa de Medicina Veterinária e Bem Estar Animal e Saúde Única - Universidade Santo Amaro, Av. Prof. Enéas de Siqueira Neto, São Paulo, SP, Brasil.
Tonhosolo R; Faculdade de Medicina - Universidade Santo Amaro. Av. Prof. Enéas de Siqueira Neto, São Paulo, SP, Brasil.
Gennari SM; Programa de Medicina Veterinária e Bem Estar Animal e Saúde Única - Universidade Santo Amaro, Av. Prof. Enéas de Siqueira Neto, São Paulo, SP, Brasil.; Laboratório de Doenças Parasitárias, Departamento de Medicina Veterinária Preventiva e Saúde Animal, Faculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo. Av. Prof. Dr. Orlando Marques de Paiva, Cidade Universitária, São Paulo, SP, Brasil.
Minervino AHH; Laboratório de Sanidade Animal, Universidade Federal do Oeste do Pará. Rua Vera Cruz s/n, Salé, Santarém, Pará, Brasil.
Marcili A; Programa de Medicina Veterinária e Bem Estar Animal e Saúde Única - Universidade Santo Amaro, Av. Prof. Enéas de Siqueira Neto, São Paulo, SP, Brasil.; Laboratório de Doenças Parasitárias, Departamento de Medicina Veterinária Preventiva e Saúde Animal, Faculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo. Av. Prof. Dr. Orlando Marques de Paiva, Cidade Universitária, São Paulo, SP, Brasil.
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Źródło :
Journal of medical entomology [J Med Entomol] 2021 Jan 12; Vol. 58 (1), pp. 403-407.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Buffaloes*
Amblyomma/*parasitology
Anoplura/*parasitology
Rhipicephalus/*parasitology
Trypanosoma vivax/*isolation & purification
Trypanosomiasis, African/*veterinary
Animals ; Brazil/epidemiology ; Cathepsin L/analysis ; Prevalence ; Protozoan Proteins/analysis ; Trypanosomiasis, African/blood ; Trypanosomiasis, African/diagnosis ; Trypanosomiasis, African/epidemiology
Czasopismo naukowe
Tytuł :
Computational Identification of Master Regulators Influencing Trypanotolerance in Cattle.
Autorzy :
Rajavel A; Breeding Informatics Group, Department of Animal Sciences, Georg-August University, Margarethe von Wrangell-Weg 7, 37075 Göttingen, Germany.
Schmitt AO; Breeding Informatics Group, Department of Animal Sciences, Georg-August University, Margarethe von Wrangell-Weg 7, 37075 Göttingen, Germany.; Center for Integrated Breeding Research (CiBreed), Albrecht-Thaer-Weg 3, Georg-August University, 37075 Göttingen, Germany.
Gültas M; Breeding Informatics Group, Department of Animal Sciences, Georg-August University, Margarethe von Wrangell-Weg 7, 37075 Göttingen, Germany.; Center for Integrated Breeding Research (CiBreed), Albrecht-Thaer-Weg 3, Georg-August University, 37075 Göttingen, Germany.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jan 08; Vol. 22 (2). Date of Electronic Publication: 2021 Jan 08.
Typ publikacji :
Journal Article
MeSH Terms :
Immunity, Innate/*genetics
Trypanosoma/*genetics
Trypanosomiasis, African/*genetics
Animals ; Cattle ; Host-Pathogen Interactions/genetics ; Humans ; Immunity, Innate/immunology ; Liver/metabolism ; Liver/parasitology ; Organ Specificity/genetics ; Proto-Oncogene Proteins c-myc/genetics ; Spleen/metabolism ; Spleen/parasitology ; Trypanosoma/pathogenicity ; Trypanosomiasis, African/parasitology ; Trypanosomiasis, African/transmission ; Trypanosomiasis, African/veterinary ; Tsetse Flies/parasitology ; Tsetse Flies/pathogenicity
Czasopismo naukowe
Tytuł :
The Actigraphy Sleep Score: A New Biomarker for Diagnosis, Disease Staging, and Monitoring in Human African Trypanosomiasis.
Autorzy :
Njamnshi AK; Brain Research Africa Initiative (BRAIN), Yaoundé, Cameroon and Geneva, Switzerland.; Neuroscience Lab, Faculty of Medicine and Biomedical Sciences, The University of Yaoundé I, Yaoundé, Cameroon.; Department of Neurology, Central Hospital Yaoundé, Yaoundé, Cameroon.
Seke Etet PF; Department of Neurological Sciences (DSNNMM), University of Verona, Verona, Italy.; Brain Research Africa Initiative (BRAIN), Yaoundé, Cameroon and Geneva, Switzerland.
Ngarka L; Brain Research Africa Initiative (BRAIN), Yaoundé, Cameroon and Geneva, Switzerland.; Neuroscience Lab, Faculty of Medicine and Biomedical Sciences, The University of Yaoundé I, Yaoundé, Cameroon.; Department of Neurology, Central Hospital Yaoundé, Yaoundé, Cameroon.
Perrig S; Sleep Studies Laboratory, Geneva University Hospitals, Geneva, Switzerland.; Brain Research Africa Initiative (BRAIN), Yaoundé, Cameroon and Geneva, Switzerland.
Olivera GC; Deparment of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.
Nfor LN; Brain Research Africa Initiative (BRAIN), Yaoundé, Cameroon and Geneva, Switzerland.; Neuroscience Lab, Faculty of Medicine and Biomedical Sciences, The University of Yaoundé I, Yaoundé, Cameroon.; Department of Neurology, Central Hospital Yaoundé, Yaoundé, Cameroon.
Njamnshi WY; Department of Neurology, Central Hospital Yaoundé, Yaoundé, Cameroon.; Neuroscience Lab, Faculty of Medicine and Biomedical Sciences, The University of Yaoundé I, Yaoundé, Cameroon.; Brain Research Africa Initiative (BRAIN), Yaoundé, Cameroon and Geneva, Switzerland.
Acho A; Neuroscience Lab, Faculty of Medicine and Biomedical Sciences, The University of Yaoundé I, Yaoundé, Cameroon.; Department of Neurology, Central Hospital Yaoundé, Yaoundé, Cameroon.
Muyembe JJ; Institut National de la Recherche Biomédicale, Kinshasa, Democratic Republic of Congo.
Bentivoglio M; Department of Neurological Sciences (DSNNMM), University of Verona, Verona, Italy.
Rottenberg M; Deparment of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.
Kennedy PGE; Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, United Kingdom.
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Źródło :
The American journal of tropical medicine and hygiene [Am J Trop Med Hyg] 2020 Dec; Vol. 103 (6), pp. 2244-2252. Date of Electronic Publication: 2020 Oct 15.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Actigraphy/*methods
Biomarkers/*analysis
Trypanosoma brucei gambiense/*isolation & purification
Trypanosomiasis, African/*diagnosis
Adolescent ; Adult ; Child ; Child, Preschool ; Female ; Humans ; Leukocyte Count ; Male ; Middle Aged ; Sleep ; Trypanosomiasis, African/cerebrospinal fluid ; Trypanosomiasis, African/parasitology ; Young Adult
Czasopismo naukowe
Tytuł :
High Trypanosoma vivax infection rates in water buffalo and cattle in the Brazilian Lower Amazon.
Autorzy :
Garcia Pérez HA; Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo, Brazil. Electronic address: .
Rodrigues CMF; Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo, Brazil; EpiAmo - Instituto Nacional de Ciência e Tecnologia da Amazônia Ocidental, Brazil.
Pivat IHV; Department of Animal Production and Industry, Faculty of Veterinary Sciences, Central University of Venezuela. Maracay, Aragua, Venezuela.
Fuzato ACR; Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo, Brazil.
Camargo EP; Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo, Brazil; EpiAmo - Instituto Nacional de Ciência e Tecnologia da Amazônia Ocidental, Brazil.
Minervino AHH; Laboratory of Animal Health, Federal University of Western Pará, Santarém, Pará, Brazil.
Teixeira MMG; Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo, Brazil; EpiAmo - Instituto Nacional de Ciência e Tecnologia da Amazônia Ocidental, Brazil.
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Źródło :
Parasitology international [Parasitol Int] 2020 Dec; Vol. 79, pp. 102162. Date of Electronic Publication: 2020 Jun 19.
Typ publikacji :
Journal Article
MeSH Terms :
Buffaloes*
Cattle Diseases/*epidemiology
Trypanosoma vivax/*isolation & purification
Trypanosomiasis, African/*veterinary
Animals ; Brazil/epidemiology ; Cattle ; Cattle Diseases/parasitology ; Genotype ; Polymerase Chain Reaction ; Prevalence ; Trypanosomiasis, African/epidemiology ; Trypanosomiasis, African/parasitology
Czasopismo naukowe
Tytuł :
Analytical sensitivity of loopamp and quantitative real-time PCR on dried blood spots and their potential role in monitoring human African trypanosomiasis elimination.
Autorzy :
Alfred Compaoré CF; Centre International of Recherche-Développement sur l'Élevage en Zone Subhumide, Unité de Recherche sur les Maladies à Vecteurs et Biodiversité, 01 BP 454, Bobo-Dioulasso 01, Burkina Faso; Université Nazi Boni, Unité de Formation et de Recherche Sciences et Techniques, 01 BP 1091, Bobo-Dioulasso, Burkina Faso.
Ilboudo H; Institut de Recherche en Sciences de la Santé, Unité de Recherche Clinique de Nanoro, 11 BP 218, Ouagadougou CMS 11, Burkina Faso.
Kaboré J; Centre International of Recherche-Développement sur l'Élevage en Zone Subhumide, Unité de Recherche sur les Maladies à Vecteurs et Biodiversité, 01 BP 454, Bobo-Dioulasso 01, Burkina Faso; Université Nazi Boni, Unité de Formation et de Recherche Sciences et Techniques, 01 BP 1091, Bobo-Dioulasso, Burkina Faso.
Kaboré JW; Centre International of Recherche-Développement sur l'Élevage en Zone Subhumide, Unité de Recherche sur les Maladies à Vecteurs et Biodiversité, 01 BP 454, Bobo-Dioulasso 01, Burkina Faso; Programme National de Lutte Contre la Trypanosomiase Humaine Africaine, BP 581, Conakry, Guinea.
Camara O; Programme National de Lutte Contre la Trypanosomiase Humaine Africaine, BP 581, Conakry, Guinea.
Bamba M; Centre International of Recherche-Développement sur l'Élevage en Zone Subhumide, Unité de Recherche sur les Maladies à Vecteurs et Biodiversité, 01 BP 454, Bobo-Dioulasso 01, Burkina Faso.
Sakande H; Centre International of Recherche-Développement sur l'Élevage en Zone Subhumide, Unité de Recherche sur les Maladies à Vecteurs et Biodiversité, 01 BP 454, Bobo-Dioulasso 01, Burkina Faso.
Koné M; Institut Pierre Richet, Unité de Recherche « Trypanosomoses », 01 BP 1500, Bouake, West Africa.
Camara M; Programme National de Lutte Contre la Trypanosomiase Humaine Africaine, BP 581, Conakry, Guinea.
Kaba D; Institut Pierre Richet, Unité de Recherche « Trypanosomoses », 01 BP 1500, Bouake, West Africa.
Gaston Belem AM; Université Nazi Boni, Unité de Formation et de Recherche Sciences et Techniques, 01 BP 1091, Bobo-Dioulasso, Burkina Faso.
Deborggraeve S; Institute of Tropical Medicine, Department of Biomedical Sciences, Nationalestraat 155, B-2000 Antwerp, Belgium.
Büscher P; Institute of Tropical Medicine, Department of Biomedical Sciences, Nationalestraat 155, B-2000 Antwerp, Belgium.
Bucheton B; Programme National de Lutte Contre la Trypanosomiase Humaine Africaine, BP 581, Conakry, Guinea; Institut de Recherche pour le Développement, UMR INTERTRYP IRD-CIRAD, Université de Montpellier, TA A-17/G, Campus International de Baillarguet, F-34398, Montpellier, France.
Lejon V; Institut de Recherche pour le Développement, UMR INTERTRYP IRD-CIRAD, Université de Montpellier, TA A-17/G, Campus International de Baillarguet, F-34398, Montpellier, France.
Jamonneau V; Institut Pierre Richet, Unité de Recherche « Trypanosomoses », 01 BP 1500, Bouake, West Africa; Institut de Recherche pour le Développement, UMR INTERTRYP IRD-CIRAD, Université de Montpellier, TA A-17/G, Campus International de Baillarguet, F-34398, Montpellier, France. Electronic address: .
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Źródło :
Experimental parasitology [Exp Parasitol] 2020 Dec; Vol. 219, pp. 108014. Date of Electronic Publication: 2020 Oct 02.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Molecular Diagnostic Techniques/*standards
Nucleic Acid Amplification Techniques/*standards
Real-Time Polymerase Chain Reaction/*standards
Trypanosoma brucei gambiense/*isolation & purification
Trypanosomiasis, African/*prevention & control
Algorithms ; Animals ; Blood Specimen Collection/methods ; Blood Specimen Collection/standards ; DNA, Protozoan/isolation & purification ; High-Throughput Screening Assays/methods ; High-Throughput Screening Assays/standards ; Humans ; Mice ; Real-Time Polymerase Chain Reaction/methods ; Sensitivity and Specificity ; Specimen Handling/methods ; Specimen Handling/standards ; Trypanosoma brucei gambiense/genetics ; Trypanosomiasis, African/blood ; Trypanosomiasis, African/diagnosis
SCR Protocol :
LAMP assay
Czasopismo naukowe
Tytuł :
Reliable, scalable functional genetics in bloodstream-form Trypanosoma congolense in vitro and in vivo.
Autorzy :
Awuah-Mensah G; School of Life Sciences, University of Nottingham, Nottingham, United Kingdom.
McDonald J; School of Life Sciences, University of Nottingham, Nottingham, United Kingdom.
Steketee PC; The Roslin Institute, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, United Kingdom.
Autheman D; Cell Surface Signalling Laboratory, Wellcome Sanger Institute, Cambridge, United Kingdom.
Whipple S; School of Life Sciences, University of Nottingham, Nottingham, United Kingdom.
D'Archivio S; School of Life Sciences, University of Nottingham, Nottingham, United Kingdom.
Brandt C; Pathogen Support Team, Wellcome Sanger Institute, Cambridge, United Kingdom.
Clare S; Pathogen Support Team, Wellcome Sanger Institute, Cambridge, United Kingdom.
Harcourt K; Pathogen Support Team, Wellcome Sanger Institute, Cambridge, United Kingdom.
Wright GJ; Cell Surface Signalling Laboratory, Wellcome Sanger Institute, Cambridge, United Kingdom.; Department of Biology, Hull York Medical School, York Biomedical Research Institute, University of York, York, United Kingdom.
Morrison LJ; The Roslin Institute, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, United Kingdom.
Gadelha C; School of Life Sciences, University of Nottingham, Nottingham, United Kingdom.
Wickstead B; School of Life Sciences, University of Nottingham, Nottingham, United Kingdom.
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Źródło :
PLoS pathogens [PLoS Pathog] 2021 Jan 22; Vol. 17 (1), pp. e1009224. Date of Electronic Publication: 2021 Jan 22 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Genetics, Microbial*
Transgenes*
Protozoan Proteins/*genetics
Trypanosoma congolense/*genetics
Trypanosoma congolense/*pathogenicity
Trypanosomiasis, African/*parasitology
Animals ; Female ; Genome, Protozoan ; In Vitro Techniques ; Male ; Mice ; Mice, Inbred BALB C ; Trypanosomiasis, African/genetics
Czasopismo naukowe
Tytuł :
Mathematical modelling and control of African animal trypanosomosis with interacting populations in West Africa-Could biting flies be important in main taining the disease endemicity?
Autorzy :
Odeniran PO; Department of Veterinary Parasitology and Entomology, Faculty of Veterinary Medicine, University of Ibadan, Ibadan, Nigeria.; Infection Medicine, Biomedical Sciences, University of Edinburgh, Scotland, United Kingdom.
Onifade AA; Department of Mathematics, Faculty of Science, University of Ibadan, Ibadan, Nigeria.
MacLeod ET; Infection Medicine, Biomedical Sciences, University of Edinburgh, Scotland, United Kingdom.
Ademola IO; Department of Veterinary Parasitology and Entomology, Faculty of Veterinary Medicine, University of Ibadan, Ibadan, Nigeria.
Alderton S; Centre for Health Informatics, Computing and Statistics (CHICAS), Lancaster Medical School, Lancaster University, Lancaster, United Kingdom.
Welburn SC; Infection Medicine, Biomedical Sciences, University of Edinburgh, Scotland, United Kingdom.; Zhejiang University - University of Edinburgh Joint Institute, Zhejiang University, Haining, China.
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Źródło :
PloS one [PLoS One] 2020 Nov 20; Vol. 15 (11), pp. e0242435. Date of Electronic Publication: 2020 Nov 20 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cattle Diseases/*prevention & control
Insect Vectors/*parasitology
Trypanosomiasis, African/*epidemiology
Trypanosomiasis, African/*veterinary
Trypanosomiasis, Bovine/*epidemiology
Tsetse Flies/*parasitology
Africa, Western/epidemiology ; Animals ; Cattle ; Cattle Diseases/parasitology ; Disease Reservoirs/parasitology ; Disease Reservoirs/veterinary ; Insecticides/pharmacology ; Models, Theoretical ; Nigeria/epidemiology ; Trypanocidal Agents/pharmacology ; Trypanosoma congolense ; Trypanosomiasis, African/prevention & control ; Trypanosomiasis, African/transmission ; Trypanosomiasis, Bovine/prevention & control
Czasopismo naukowe
Tytuł :
Trypanosomosis prevalence in natural field-based infection: insights into systematic review and meta-analysis of studies from 1980 to 2018 on The Gambian ruminants with special emphasis on cattle.
Autorzy :
Olaniyan OF; Department of Animal Science, Faculty of Agriculture, Ege University, 35040, Izmir, Turkey. .; West Africa Livestock Innovation Centre, PMB 14, Banjul, The Gambia. .
Kaya I; Department of Animal Science, Faculty of Agriculture, Ege University, 35040, Izmir, Turkey.
Secka A; West Africa Livestock Innovation Centre, PMB 14, Banjul, The Gambia.
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Źródło :
Tropical animal health and production [Trop Anim Health Prod] 2020 Nov 21; Vol. 53 (1), pp. 25. Date of Electronic Publication: 2020 Nov 21.
Typ publikacji :
Journal Article; Meta-Analysis; Systematic Review
MeSH Terms :
Cattle Diseases/*epidemiology
Goat Diseases/*epidemiology
Sheep Diseases/*epidemiology
Trypanosomiasis, African/*veterinary
Trypanosomiasis, Bovine/*epidemiology
Animals ; Cattle ; Cattle Diseases/parasitology ; Gambia/epidemiology ; Goat Diseases/parasitology ; Goats ; Prevalence ; Sheep ; Sheep Diseases/parasitology ; Sheep, Domestic ; Trypanosoma brucei brucei/physiology ; Trypanosoma congolense/physiology ; Trypanosoma vivax/physiology ; Trypanosomiasis, African/epidemiology ; Trypanosomiasis, African/parasitology ; Trypanosomiasis, Bovine/parasitology
Czasopismo naukowe
Tytuł :
Trypa-NO! contributes to the elimination of gambiense human African trypanosomiasis by combining tsetse control with "screen, diagnose and treat" using innovative tools and strategies.
Autorzy :
Ndung'u JM; Foundation for Innovative New Diagnostics (FIND), Geneva, Switzerland.
Boulangé A; Centre International de Recherche-Développement sur l'Elevage en zone Subhumide (CIRDES), Bobo Dioulasso, Burkina Faso.; Centre International de Recherche Agronomique pour le Développement (CIRAD), UMR INTERTRYP, Montpellier, France.
Picado A; Foundation for Innovative New Diagnostics (FIND), Geneva, Switzerland.
Mugenyi A; Coordinating Office for Control of Trypanosomiasis in Uganda (COCTU), Entebbe, Uganda.
Mortensen A; Vestergaard SA, Lausanne, Switzerland.
Hope A; Liverpool School of Tropical Medicine (LSTM), Liverpool, United Kingdom.
Mollo BG; Institut de Recherche en Elevage pour le Développement (IRED), N'Djamena, Chad.
Bucheton B; Institut de Recherche pour le Développement (IRD), INTERTRYP, CIRAD, Université Montpellier, Montpellier, France.; Programme National de Lutte contre la Trypanosomiase Humaine Africaine, Conakry, Guinea.
Wamboga C; Ministry of Health (MOH), Kampala, Uganda.
Waiswa C; Coordinating Office for Control of Trypanosomiasis in Uganda (COCTU), Entebbe, Uganda.
Kaba D; Institut Pierre Richet/Institut National de Santé Publique (IPR/INSP), Bouaké, Côte d'Ivoire.
Matovu E; College of Veterinary Medicine, Animal Resources and Biosecurity (COVAB), Makerere University, Kampala, Uganda.
Courtin F; Institut de Recherche pour le Développement (IRD), INTERTRYP, CIRAD, Université Montpellier, Montpellier, France.; Institut Pierre Richet/Institut National de Santé Publique (IPR/INSP), Bouaké, Côte d'Ivoire.
Garrod G; Liverpool School of Tropical Medicine (LSTM), Liverpool, United Kingdom.
Gimonneau G; Centre International de Recherche-Développement sur l'Elevage en zone Subhumide (CIRDES), Bobo Dioulasso, Burkina Faso.; Centre International de Recherche Agronomique pour le Développement (CIRAD), UMR INTERTRYP, Montpellier, France.
Bingham GV; Vestergaard SA, Lausanne, Switzerland.
Hassane HM; Institut de Recherche en Elevage pour le Développement (IRED), N'Djamena, Chad.
Tirados I; Liverpool School of Tropical Medicine (LSTM), Liverpool, United Kingdom.
Saldanha I; Liverpool School of Tropical Medicine (LSTM), Liverpool, United Kingdom.
Kabore J; Centre International de Recherche-Développement sur l'Elevage en zone Subhumide (CIRDES), Bobo Dioulasso, Burkina Faso.
Rayaisse JB; Centre International de Recherche-Développement sur l'Elevage en zone Subhumide (CIRDES), Bobo Dioulasso, Burkina Faso.
Bart JM; Institut de Recherche pour le Développement (IRD), INTERTRYP, CIRAD, Université Montpellier, Montpellier, France.
Lingley J; Liverpool School of Tropical Medicine (LSTM), Liverpool, United Kingdom.
Esterhuizen J; Liverpool School of Tropical Medicine (LSTM), Liverpool, United Kingdom.
Longbottom J; Liverpool School of Tropical Medicine (LSTM), Liverpool, United Kingdom.
Pulford J; Liverpool School of Tropical Medicine (LSTM), Liverpool, United Kingdom.
Kouakou L; Programme National d'Elimination de la THA (PNETHA), Abidjan, Côte d'Ivoire.
Sanogo L; Centre International de Recherche-Développement sur l'Elevage en zone Subhumide (CIRDES), Bobo Dioulasso, Burkina Faso.
Cunningham L; Liverpool School of Tropical Medicine (LSTM), Liverpool, United Kingdom.
Camara M; Institut de Recherche pour le Développement (IRD), INTERTRYP, CIRAD, Université Montpellier, Montpellier, France.
Koffi M; Université Jean Lorougnon Guédé (UJLoG), Daloa, Côte d'Ivoire.
Stanton M; Liverpool School of Tropical Medicine (LSTM), Liverpool, United Kingdom.
Lehane M; Liverpool School of Tropical Medicine (LSTM), Liverpool, United Kingdom.
Kagbadouno MS; Programme National de Lutte contre la Trypanosomiase Humaine Africaine, Conakry, Guinea.
Camara O; Programme National de Lutte contre la Trypanosomiase Humaine Africaine, Conakry, Guinea.
Bessell P; Epi Interventions, Edinburgh, United Kingdom.
Mallaye P; Programme National de Lutte contre la Trypanosomiase Humaine Africaine (PNLTHA), Chad.
Solano P; Institut de Recherche pour le Développement (IRD), INTERTRYP, CIRAD, Université Montpellier, Montpellier, France.
Selby R; Liverpool School of Tropical Medicine (LSTM), Liverpool, United Kingdom.
Dunkley S; Liverpool School of Tropical Medicine (LSTM), Liverpool, United Kingdom.
Torr S; Liverpool School of Tropical Medicine (LSTM), Liverpool, United Kingdom.
Biéler S; Foundation for Innovative New Diagnostics (FIND), Geneva, Switzerland.
Lejon V; Institut de Recherche pour le Développement (IRD), INTERTRYP, CIRAD, Université Montpellier, Montpellier, France.
Jamonneau V; Institut de Recherche pour le Développement (IRD), INTERTRYP, CIRAD, Université Montpellier, Montpellier, France.; Ministry of Health (MOH), Kampala, Uganda.
Yoni W; Centre International de Recherche-Développement sur l'Elevage en zone Subhumide (CIRDES), Bobo Dioulasso, Burkina Faso.
Katz Z; Foundation for Innovative New Diagnostics (FIND), Geneva, Switzerland.
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Źródło :
PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2020 Nov 12; Vol. 14 (11), pp. e0008738. Date of Electronic Publication: 2020 Nov 12 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
International Cooperation*
Trypanosomiasis, African*/diagnosis
Trypanosomiasis, African*/drug therapy
Trypanosomiasis, African*/prevention & control
Mass Screening/*methods
Trypanosoma brucei gambiense/*drug effects
Trypanosoma brucei rhodesiense/*drug effects
Animals ; Antibodies, Protozoan/blood ; Chad ; Cote d'Ivoire ; Disease Vectors ; Guinea ; Humans ; Insect Control/methods ; Insecticides/administration & dosage ; Trypanosoma brucei gambiense/isolation & purification ; Trypanosoma brucei rhodesiense/isolation & purification ; Tsetse Flies/parasitology ; Uganda
Czasopismo naukowe
Tytuł :
Veterinary trypanocidal benzoxaboroles are peptidase-activated prodrugs.
Autorzy :
Giordani F; Wellcome Centre for Integrative Parasitology, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom.
Paape D; Wellcome Centre for Integrative Parasitology, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom.
Vincent IM; Wellcome Centre for Integrative Parasitology, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom.
Pountain AW; Wellcome Centre for Integrative Parasitology, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom.
Fernández-Cortés F; Wellcome Centre for Integrative Parasitology, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom.
Rico E; Wellcome Centre for Anti-Infectives Research, School of Life Sciences, University of Dundee, Dundee, United Kingdom.
Zhang N; Wellcome Centre for Anti-Infectives Research, School of Life Sciences, University of Dundee, Dundee, United Kingdom.
Morrison LJ; Roslin Institute, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Midlothian, United Kingdom.
Freund Y; Anacor Pharmaceuticals, Inc., Palo Alto, California, United States of America.
Witty MJ; Global Alliance for Livestock and Veterinary Medicine, Pentlands Science Park, Penicuik, Edinburgh, United Kingdom.
Peter R; Global Alliance for Livestock and Veterinary Medicine, Pentlands Science Park, Penicuik, Edinburgh, United Kingdom.
Edwards DY; Wellcome Centre for Anti-Infectives Research, School of Life Sciences, University of Dundee, Dundee, United Kingdom.
Wilkes JM; Wellcome Centre for Integrative Parasitology, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom.
van der Hooft JJJ; Glasgow Polyomics, Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom.; Current address: Bioinformatics Group, Wageningen University, Wageningen, the Netherlands.
Regnault C; Glasgow Polyomics, Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom.
Read KD; Wellcome Centre for Anti-Infectives Research, School of Life Sciences, University of Dundee, Dundee, United Kingdom.
Horn D; Wellcome Centre for Anti-Infectives Research, School of Life Sciences, University of Dundee, Dundee, United Kingdom.
Field MC; Wellcome Centre for Anti-Infectives Research, School of Life Sciences, University of Dundee, Dundee, United Kingdom.; Institute of Parasitology, Biology Centre of the Czech Academy of Sciences, České Budějovice, Czech Republic.
Barrett MP; Wellcome Centre for Integrative Parasitology, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom.; Glasgow Polyomics, Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom.
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Źródło :
PLoS pathogens [PLoS Pathog] 2020 Nov 03; Vol. 16 (11), pp. e1008932. Date of Electronic Publication: 2020 Nov 03 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Boron Compounds/*metabolism
Carboxypeptidases/*metabolism
Trypanocidal Agents/*metabolism
Trypanosoma brucei brucei/*enzymology
Trypanosoma congolense/*enzymology
Trypanosoma vivax/*enzymology
Trypanosomiasis, African/*veterinary
Valine/*analogs & derivatives
Animals ; Carboxylic Acids/metabolism ; Drug Resistance ; Female ; Livestock ; Mice ; Parasitemia/veterinary ; Prodrugs/metabolism ; Protozoan Proteins/metabolism ; Trypanosoma brucei brucei/drug effects ; Trypanosoma congolense/drug effects ; Trypanosoma vivax/drug effects ; Trypanosomiasis, African/drug therapy ; Trypanosomiasis, African/parasitology ; Valine/metabolism
Czasopismo naukowe
Tytuł :
Development and implementation of a strategy for intensified screening for gambiense human African trypanosomiasis in Kongo Central province, DRC.
Autorzy :
Lumbala C; Directorate of Disease Control, Ministry of Public Health, Democratic Republic of the Congo.; Global Health Institute, Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium.
Kayembe S; Foundation for Innovative New Diagnostics (FIND), Geneva, Switzerland.
Makabuza J; Programme National de Lutte Contre la Trypanosomiase Humaine Africaine, Kinshasa, République Démocratique du Congo.
Lutumba P; Kinshasa University, Kinshasa, Democratic Republic of the Congo.
Van Geertruyden JP; Global Health Institute, Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium.
Bessell PR; Epi Interventions, Edinburgh, United Kingdom.
Ndung'u JM; Foundation for Innovative New Diagnostics (FIND), Geneva, Switzerland.
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Źródło :
PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2020 Oct 15; Vol. 14 (10), pp. e0008779. Date of Electronic Publication: 2020 Oct 15 (Print Publication: 2020).
Typ publikacji :
Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Mass Screening/*methods
Trypanosoma brucei gambiense/*isolation & purification
Trypanosomiasis, African/*diagnosis
Animals ; Democratic Republic of the Congo/epidemiology ; Diagnostic Tests, Routine ; Humans ; Molecular Diagnostic Techniques ; Nucleic Acid Amplification Techniques ; Trypanosoma brucei gambiense/classification ; Trypanosoma brucei gambiense/genetics ; Trypanosomiasis, African/epidemiology ; Trypanosomiasis, African/parasitology
SCR Protocol :
LAMP assay
Czasopismo naukowe
Tytuł :
A new automated chilled adult release system for the aerial distribution of sterile male tsetse flies.
Autorzy :
Mirieri CK; Insect Pest Control Laboratory, Joint FAO/IAEA Programme of Nuclear Techniques in Food and Agriculture, Vienna, Austria.; Laboratory of Virology, Wageningen University and Research, Wageningen, The Netherlands.
Mutika GN; Insect Pest Control Laboratory, Joint FAO/IAEA Programme of Nuclear Techniques in Food and Agriculture, Vienna, Austria.
Bruno J; AEWO, Saint Jean le Vieux, France.
Seck MT; Institut Sénégalais de Recherches Agricoles, Laboratoire National d'Elevage et de Recherches Vétérinaires, Dakar-Hann, Sénégal.
Sall B; Direction des Services Vétérinaires, Dakar, Sénégal.
Parker AG; Insect Pest Control Laboratory, Joint FAO/IAEA Programme of Nuclear Techniques in Food and Agriculture, Vienna, Austria.
van Oers MM; Laboratory of Virology, Wageningen University and Research, Wageningen, The Netherlands.
Vreysen MJB; Insect Pest Control Laboratory, Joint FAO/IAEA Programme of Nuclear Techniques in Food and Agriculture, Vienna, Austria.
Bouyer J; Insect Pest Control Laboratory, Joint FAO/IAEA Programme of Nuclear Techniques in Food and Agriculture, Vienna, Austria.; CIRAD, UMR ASTRE, Montpellier, France.
Abd-Alla AMM; Insect Pest Control Laboratory, Joint FAO/IAEA Programme of Nuclear Techniques in Food and Agriculture, Vienna, Austria.
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Źródło :
PloS one [PLoS One] 2020 Sep 28; Vol. 15 (9), pp. e0232306. Date of Electronic Publication: 2020 Sep 28 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cold Temperature/*adverse effects
Infertility, Male/*veterinary
Pest Control, Biological/*methods
Trypanosomiasis, African/*prevention & control
Tsetse Flies/*physiology
Animals ; Disease Vectors ; Female ; Flight, Animal/physiology ; Humans ; Infertility, Male/etiology ; Livestock/parasitology ; Male ; Pest Control, Biological/instrumentation ; Senegal ; Sexual Behavior, Animal/physiology ; Trypanosoma/pathogenicity ; Trypanosomiasis, African/parasitology ; Trypanosomiasis, African/veterinary ; Tsetse Flies/parasitology
Czasopismo naukowe
Tytuł :
The complex health seeking pathway of a human African trypanosomiasis patient in Côte d'Ivoire underlines the need of setting up passive surveillance systems.
Autorzy :
Koné M; Unité de Recherche « Trypanosomoses », Institut Pierre Richet, Bouaké, Côte d'Ivoire.; Laboratoire de Biodiversité et Gestion des Ecosystèmes Tropicaux, Unité de Recherche en Génétique et Epidémiologie Moléculaire, Université Jean Lorougnon Guédé, UFR Environnement, Daloa, Côte d'Ivoire.
N'Gouan EK; Projet de Recherches Cliniques sur la Trypanosomiase (PRCT), Daloa, Côte d'Ivoire.
Kaba D; Unité de Recherche « Trypanosomoses », Institut Pierre Richet, Bouaké, Côte d'Ivoire.
Koffi M; Laboratoire de Biodiversité et Gestion des Ecosystèmes Tropicaux, Unité de Recherche en Génétique et Epidémiologie Moléculaire, Université Jean Lorougnon Guédé, UFR Environnement, Daloa, Côte d'Ivoire.
Kouakou L; Programme National d'Élimination de la Trypanosomose Humaine Africaine, Abidjan, Côte d'Ivoire.
N'Dri L; Unité de Recherche « Trypanosomoses », Institut Pierre Richet, Bouaké, Côte d'Ivoire.
Kouamé CM; Unité de Recherche « Trypanosomoses », Institut Pierre Richet, Bouaké, Côte d'Ivoire.
Nanan VK; Direction Départementale de la Marahoué, District sanitaire de Sinfra, Ministère de la Santé et de l'Hygiène Publique, Abidjan, Côte d'Ivoire.
Tapé GA; Direction départementale de la santé de la Marahoué, Centre de Santé Urbain de Bonon, Ministère de la Santé et de l'Hygiène Publique, Abidjan Côte d'Ivoire.
Coulibaly B; Unité de Recherche « Trypanosomoses », Institut Pierre Richet, Bouaké, Côte d'Ivoire.
Courtin F; Unité de Recherche « Trypanosomoses », Institut Pierre Richet, Bouaké, Côte d'Ivoire.; Unité Mixte de Recherche IRD-CIRAD 177, INTERTRYP, Institut de Recherche pour le Développement (IRD) Université de Montpellier, Montpellier, France.
Ahouty B; Laboratoire de Biodiversité et Gestion des Ecosystèmes Tropicaux, Unité de Recherche en Génétique et Epidémiologie Moléculaire, Université Jean Lorougnon Guédé, UFR Environnement, Daloa, Côte d'Ivoire.
Djohan V; Unité de Recherche « Trypanosomoses », Institut Pierre Richet, Bouaké, Côte d'Ivoire.
Bucheton B; Unité Mixte de Recherche IRD-CIRAD 177, INTERTRYP, Institut de Recherche pour le Développement (IRD) Université de Montpellier, Montpellier, France.
Solano P; Unité Mixte de Recherche IRD-CIRAD 177, INTERTRYP, Institut de Recherche pour le Développement (IRD) Université de Montpellier, Montpellier, France.
Büscher P; Department of Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.
Lejon V; Unité Mixte de Recherche IRD-CIRAD 177, INTERTRYP, Institut de Recherche pour le Développement (IRD) Université de Montpellier, Montpellier, France.
Jamonneau V; Unité de Recherche « Trypanosomoses », Institut Pierre Richet, Bouaké, Côte d'Ivoire.; Unité Mixte de Recherche IRD-CIRAD 177, INTERTRYP, Institut de Recherche pour le Développement (IRD) Université de Montpellier, Montpellier, France.
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Źródło :
PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2020 Sep 14; Vol. 14 (9), pp. e0008588. Date of Electronic Publication: 2020 Sep 14 (Print Publication: 2020).
Typ publikacji :
Case Reports; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Delayed Diagnosis/*economics
Neglected Diseases/*diagnosis
Neglected Diseases/*drug therapy
Trypanosomiasis, African/*diagnosis
Trypanosomiasis, African/*drug therapy
Blood/parasitology ; Cerebrospinal Fluid/parasitology ; Child ; Chronic Disease Indicators ; Cote d'Ivoire/epidemiology ; Female ; Humans ; Neglected Diseases/parasitology ; Patient Care Management/economics ; Trypanosoma brucei gambiense/isolation & purification ; Trypanosomiasis, African/parasitology
Czasopismo naukowe
Tytuł :
Differential virulence of Trypanosoma brucei rhodesiense isolates does not influence the outcome of treatment with anti-trypanosomal drugs in the mouse model.
Autorzy :
Ndung'u K; Biotechnology Research Institute, Kenya Agricultural and Livestock Research Organization, Kikuyu, Kenya.
Murilla GA; Biotechnology Research Institute, Kenya Agricultural and Livestock Research Organization, Kikuyu, Kenya.; KAG EAST University, Nairobi, Kenya.
Thuita JK; Biotechnology Research Institute, Kenya Agricultural and Livestock Research Organization, Kikuyu, Kenya.; Meru University of Science and Technology, Meru, Kenya.
Ngae GN; Food Crops Research Institute, Kenya Agricultural and Livestock Research Organization, Nairobi, Kenya.
Auma JE; Biotechnology Research Institute, Kenya Agricultural and Livestock Research Organization, Kikuyu, Kenya.
Gitonga PK; Biotechnology Research Institute, Kenya Agricultural and Livestock Research Organization, Kikuyu, Kenya.
Thungu DK; Biotechnology Research Institute, Kenya Agricultural and Livestock Research Organization, Kikuyu, Kenya.
Kurgat RK; Biotechnology Research Institute, Kenya Agricultural and Livestock Research Organization, Kikuyu, Kenya.
Chemuliti JK; Biotechnology Research Institute, Kenya Agricultural and Livestock Research Organization, Kikuyu, Kenya.
Mdachi RE; Biotechnology Research Institute, Kenya Agricultural and Livestock Research Organization, Kikuyu, Kenya.
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Źródło :
PloS one [PLoS One] 2020 Nov 05; Vol. 15 (11), pp. e0229060. Date of Electronic Publication: 2020 Nov 05 (Print Publication: 2020).
Typ publikacji :
Journal Article
MeSH Terms :
Trypanocidal Agents/*pharmacology
Trypanosoma brucei rhodesiense/*drug effects
Trypanosomiasis, African/*drug therapy
Virulence/*drug effects
Animals ; Diminazene/analogs & derivatives ; Diminazene/pharmacology ; Disease Models, Animal ; Drug Resistance/drug effects ; Kenya ; Male ; Melarsoprol/pharmacology ; Mice ; Pentamidine/pharmacology ; Suramin/pharmacology ; Treatment Outcome ; Trypanosomiasis, African/parasitology ; Uganda
Czasopismo naukowe
Tytuł :
The therapeutic potential of phytol towards Trypanosoma congolense infection and the inhibitory effects against trypanosomal sialidase.
Autorzy :
Saad SB; Department of Biochemistry, Ahmadu Bello University, Zaria, Nigeria; Department of Biochemistry, Yusuf Maitama Sule University, Kano, Nigeria.
Ibrahim MA; Department of Biochemistry, Ahmadu Bello University, Zaria, Nigeria. Electronic address: .
Jatau ID; Department of Veterinary Parasitology and Entomology, Ahmadu Bello University, Zaria, Nigeria.
Shuaibu MN; Department of Biochemistry, Ahmadu Bello University, Zaria, Nigeria.
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Źródło :
Experimental parasitology [Exp Parasitol] 2020 Sep; Vol. 216, pp. 107943. Date of Electronic Publication: 2020 Jun 27.
Typ publikacji :
Journal Article
MeSH Terms :
Antiprotozoal Agents/*therapeutic use
Enzyme Inhibitors/*pharmacology
Neuraminidase/*antagonists & inhibitors
Phytol/*therapeutic use
Trypanosoma congolense/*drug effects
Trypanosomiasis, African/*veterinary
Animals ; Antiprotozoal Agents/pharmacology ; Enzyme Inhibitors/therapeutic use ; Livestock ; Neglected Diseases/drug therapy ; Neglected Diseases/veterinary ; Neuraminidase/chemistry ; Neuraminidase/isolation & purification ; Phytol/pharmacology ; Random Allocation ; Rats ; Rats, Wistar ; Trypanosoma congolense/enzymology ; Trypanosomiasis, African/drug therapy
Czasopismo naukowe
Tytuł :
Assessing the effect of insecticide-treated cattle on tsetse abundance and trypanosome transmission at the wildlife-livestock interface in Serengeti, Tanzania.
Autorzy :
Lord JS; Dept. of Vector Biology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
Lea RS; Dept. of Vector Biology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
Allan FK; Roslin Institute, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, United Kingdom.
Byamungu M; Vector and Vector-Borne Diseases Research Institute, Tanga, Tanzania.
Hall DR; Natural Resources Institute, University of Greenwich, Chatham, United Kingdom.
Lingley J; Dept. of Vector Biology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
Mramba F; Vector and Vector-Borne Diseases Research Institute, Tanga, Tanzania.
Paxton E; Roslin Institute, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, United Kingdom.
Vale GA; Natural Resources Institute, University of Greenwich, Chatham, United Kingdom.; SACEMA, University of Stellenbosch, Stellenbosch, South Africa.
Hargrove JW; SACEMA, University of Stellenbosch, Stellenbosch, South Africa.
Morrison LJ; Roslin Institute, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, United Kingdom.
Torr SJ; Dept. of Vector Biology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
Auty HK; Epidemiology Research Unit, SRUC, An Lochran, Inverness, IV2 5NA, United Kingdom.; Institute of Biodiversity, Animal Health and Comparative Medicine, University of Glasgow, Glasgow, United Kingdom.
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Źródło :
PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2020 Aug 25; Vol. 14 (8), pp. e0008288. Date of Electronic Publication: 2020 Aug 25 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Animals, Wild*
Livestock*
Cattle Diseases/*epidemiology
Cattle Diseases/*transmission
Insecticides/*pharmacology
Trypanosomiasis, African/*epidemiology
Trypanosomiasis, African/*transmission
Animals ; Cattle ; Cattle Diseases/prevention & control ; Female ; Models, Theoretical ; Polymerase Chain Reaction ; Prevalence ; Pyrethrins ; Tanzania/epidemiology ; Trypanosoma ; Trypanosoma brucei rhodesiense ; Trypanosomiasis, African/prevention & control ; Tsetse Flies
Czasopismo naukowe
Tytuł :
Comparison of loop-mediated isothermal amplification (LAMP) and PCR for the diagnosis of infection with Trypanosoma brucei ssp. in equids in The Gambia.
Autorzy :
Gummery L; Weipers Centre Equine Hospital, School of Veterinary Medicine, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom.
Jallow S; Gambia Horse and Donkey Trust, Sambel Kunda, The Gambia.
Raftery AG; Weipers Centre Equine Hospital, School of Veterinary Medicine, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom.
Bennet E; Weipers Centre Equine Hospital, School of Veterinary Medicine, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom.
Rodgers J; Institute of Biodiversity, Animal Health and Comparative Medicine, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom.
Sutton DGM; Weipers Centre Equine Hospital, School of Veterinary Medicine, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom.
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Źródło :
PloS one [PLoS One] 2020 Aug 24; Vol. 15 (8), pp. e0237187. Date of Electronic Publication: 2020 Aug 24 (Print Publication: 2020).
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Horse Diseases/*parasitology
Horses/*parasitology
Molecular Diagnostic Techniques/*methods
Nucleic Acid Amplification Techniques/*methods
Polymerase Chain Reaction/*methods
Trypanosoma brucei brucei/*genetics
Trypanosomiasis, African/*diagnosis
Trypanosomiasis, African/*veterinary
Animals ; Cross-Sectional Studies ; DNA, Protozoan/blood ; DNA, Protozoan/genetics ; Female ; Gambia ; Male ; Molecular Diagnostic Techniques/economics ; Nucleic Acid Amplification Techniques/economics ; Polymerase Chain Reaction/economics ; Prospective Studies ; Sensitivity and Specificity ; Trypanosomiasis, African/parasitology
SCR Protocol :
LAMP assay
Czasopismo naukowe
Tytuł :
Delivering 'tiny targets' in a remote region of southern Chad: a cost analysis of tsetse control in the Mandoul sleeping sickness focus.
Autorzy :
Rayaisse JB; Centre International de Recherche-Développement sur l'Elevage en zone Subhumide (CIRDES), Bobo-Dioulasso, Burkina Faso.
Courtin F; Institut Pierre Richet (IPR), Bouaké, Côte d'Ivoire.; Institut de Recherche pour le Développement (IRD), Unité mixte de recherche, (UMR) 177 Intertryp IRD-Centre de coopération internationale en recherche agronomique pour le développement (CIRAD), Université Montpellier, Montpellier, France.
Mahamat MH; Institut de Recherche en Elevage pour le Développement (IRED), N'Djaména, Chad.
Chérif M; Institut de Recherche en Elevage pour le Développement (IRED), N'Djaména, Chad.
Yoni W; Centre International de Recherche-Développement sur l'Elevage en zone Subhumide (CIRDES), Bobo-Dioulasso, Burkina Faso.
Gadjibet NMO; Institut de Recherche en Elevage pour le Développement (IRED), N'Djaména, Chad.
Peka M; Programme National de Lutte contre la Trypanosomiase Humaine Africaine (PNLTHA), N'Djaména, Chad.
Solano P; Institut de Recherche pour le Développement (IRD), Unité mixte de recherche, (UMR) 177 Intertryp IRD-Centre de coopération internationale en recherche agronomique pour le développement (CIRAD), Université Montpellier, Montpellier, France.
Torr SJ; Liverpool School of Tropical Medicine (LSTM), Liverpool, Merseyside, UK.
Shaw APM; Infection Medicine, Deanery of Biomedical Sciences, College of Medicine and Veterinary Medicine, The University of Edinburgh, Edinburgh, UK. .; AP Consultants, Walworth Enterprise Centre, Andover, UK. .
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Źródło :
Parasites & vectors [Parasit Vectors] 2020 Aug 14; Vol. 13 (1), pp. 419. Date of Electronic Publication: 2020 Aug 14.
Typ publikacji :
Journal Article
MeSH Terms :
Costs and Cost Analysis*
Insect Control*/economics
Insect Control*/methods
Trypanosomiasis, African*/prevention & control
Trypanosomiasis, African*/transmission
Tsetse Flies*/parasitology
Animals ; Cattle ; Chad/epidemiology ; Humans ; Insect Vectors/parasitology ; Insecticides/economics
Czasopismo naukowe

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