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Wyszukujesz frazę ""Trypanosomiasis, African"" wg kryterium: Temat


Tytuł :
Reliable, scalable functional genetics in bloodstream-form Trypanosoma congolense in vitro and in vivo.
Autorzy :
Awuah-Mensah G; School of Life Sciences, University of Nottingham, Nottingham, United Kingdom.
McDonald J; School of Life Sciences, University of Nottingham, Nottingham, United Kingdom.
Steketee PC; The Roslin Institute, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, United Kingdom.
Autheman D; Cell Surface Signalling Laboratory, Wellcome Sanger Institute, Cambridge, United Kingdom.
Whipple S; School of Life Sciences, University of Nottingham, Nottingham, United Kingdom.
D'Archivio S; School of Life Sciences, University of Nottingham, Nottingham, United Kingdom.
Brandt C; Pathogen Support Team, Wellcome Sanger Institute, Cambridge, United Kingdom.
Clare S; Pathogen Support Team, Wellcome Sanger Institute, Cambridge, United Kingdom.
Harcourt K; Pathogen Support Team, Wellcome Sanger Institute, Cambridge, United Kingdom.
Wright GJ; Cell Surface Signalling Laboratory, Wellcome Sanger Institute, Cambridge, United Kingdom.; Department of Biology, Hull York Medical School, York Biomedical Research Institute, University of York, York, United Kingdom.
Morrison LJ; The Roslin Institute, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, United Kingdom.
Gadelha C; School of Life Sciences, University of Nottingham, Nottingham, United Kingdom.
Wickstead B; School of Life Sciences, University of Nottingham, Nottingham, United Kingdom.
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Źródło :
PLoS pathogens [PLoS Pathog] 2021 Jan 22; Vol. 17 (1), pp. e1009224. Date of Electronic Publication: 2021 Jan 22 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Genetics, Microbial*
Transgenes*
Protozoan Proteins/*genetics
Trypanosoma congolense/*genetics
Trypanosoma congolense/*pathogenicity
Trypanosomiasis, African/*parasitology
Animals ; Female ; Genome, Protozoan ; In Vitro Techniques ; Male ; Mice ; Mice, Inbred BALB C ; Trypanosomiasis, African/genetics
Czasopismo naukowe
Tytuł :
Veterinary trypanocidal benzoxaboroles are peptidase-activated prodrugs.
Autorzy :
Giordani F; Wellcome Centre for Integrative Parasitology, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom.
Paape D; Wellcome Centre for Integrative Parasitology, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom.
Vincent IM; Wellcome Centre for Integrative Parasitology, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom.
Pountain AW; Wellcome Centre for Integrative Parasitology, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom.
Fernández-Cortés F; Wellcome Centre for Integrative Parasitology, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom.
Rico E; Wellcome Centre for Anti-Infectives Research, School of Life Sciences, University of Dundee, Dundee, United Kingdom.
Zhang N; Wellcome Centre for Anti-Infectives Research, School of Life Sciences, University of Dundee, Dundee, United Kingdom.
Morrison LJ; Roslin Institute, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Midlothian, United Kingdom.
Freund Y; Anacor Pharmaceuticals, Inc., Palo Alto, California, United States of America.
Witty MJ; Global Alliance for Livestock and Veterinary Medicine, Pentlands Science Park, Penicuik, Edinburgh, United Kingdom.
Peter R; Global Alliance for Livestock and Veterinary Medicine, Pentlands Science Park, Penicuik, Edinburgh, United Kingdom.
Edwards DY; Wellcome Centre for Anti-Infectives Research, School of Life Sciences, University of Dundee, Dundee, United Kingdom.
Wilkes JM; Wellcome Centre for Integrative Parasitology, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom.
van der Hooft JJJ; Glasgow Polyomics, Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom.; Current address: Bioinformatics Group, Wageningen University, Wageningen, the Netherlands.
Regnault C; Glasgow Polyomics, Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom.
Read KD; Wellcome Centre for Anti-Infectives Research, School of Life Sciences, University of Dundee, Dundee, United Kingdom.
Horn D; Wellcome Centre for Anti-Infectives Research, School of Life Sciences, University of Dundee, Dundee, United Kingdom.
Field MC; Wellcome Centre for Anti-Infectives Research, School of Life Sciences, University of Dundee, Dundee, United Kingdom.; Institute of Parasitology, Biology Centre of the Czech Academy of Sciences, České Budějovice, Czech Republic.
Barrett MP; Wellcome Centre for Integrative Parasitology, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom.; Glasgow Polyomics, Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom.
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Źródło :
PLoS pathogens [PLoS Pathog] 2020 Nov 03; Vol. 16 (11), pp. e1008932. Date of Electronic Publication: 2020 Nov 03 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Boron Compounds/*metabolism
Carboxypeptidases/*metabolism
Trypanocidal Agents/*metabolism
Trypanosoma brucei brucei/*enzymology
Trypanosoma congolense/*enzymology
Trypanosoma vivax/*enzymology
Trypanosomiasis, African/*veterinary
Valine/*analogs & derivatives
Animals ; Carboxylic Acids/metabolism ; Drug Resistance ; Female ; Livestock ; Mice ; Parasitemia/veterinary ; Prodrugs/metabolism ; Protozoan Proteins/metabolism ; Trypanosoma brucei brucei/drug effects ; Trypanosoma congolense/drug effects ; Trypanosoma vivax/drug effects ; Trypanosomiasis, African/drug therapy ; Trypanosomiasis, African/parasitology ; Valine/metabolism
Czasopismo naukowe
Tytuł :
The therapeutic potential of phytol towards Trypanosoma congolense infection and the inhibitory effects against trypanosomal sialidase.
Autorzy :
Saad SB; Department of Biochemistry, Ahmadu Bello University, Zaria, Nigeria; Department of Biochemistry, Yusuf Maitama Sule University, Kano, Nigeria.
Ibrahim MA; Department of Biochemistry, Ahmadu Bello University, Zaria, Nigeria. Electronic address: .
Jatau ID; Department of Veterinary Parasitology and Entomology, Ahmadu Bello University, Zaria, Nigeria.
Shuaibu MN; Department of Biochemistry, Ahmadu Bello University, Zaria, Nigeria.
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Źródło :
Experimental parasitology [Exp Parasitol] 2020 Sep; Vol. 216, pp. 107943. Date of Electronic Publication: 2020 Jun 27.
Typ publikacji :
Journal Article
MeSH Terms :
Antiprotozoal Agents/*therapeutic use
Enzyme Inhibitors/*pharmacology
Neuraminidase/*antagonists & inhibitors
Phytol/*therapeutic use
Trypanosoma congolense/*drug effects
Trypanosomiasis, African/*veterinary
Animals ; Antiprotozoal Agents/pharmacology ; Enzyme Inhibitors/therapeutic use ; Livestock ; Neglected Diseases/drug therapy ; Neglected Diseases/veterinary ; Neuraminidase/chemistry ; Neuraminidase/isolation & purification ; Phytol/pharmacology ; Random Allocation ; Rats ; Rats, Wistar ; Trypanosoma congolense/enzymology ; Trypanosomiasis, African/drug therapy
Czasopismo naukowe
Tytuł :
Molecular identification of diminazene aceturate-resistant strains of Trypanosoma congolense in naturally infected domestic animals of Yoko in the centre region of Cameroon.
Autorzy :
Mewamba EM; Molecular Parasitology and Entomology Unit, Department of Biochemistry, Faculty of Science, University of Dschang, PO. Box 67, Dschang, Cameroon.
Farikou O; University of Bamenda, Cameroon.
Kamga RMN; Molecular Parasitology and Entomology Unit, Department of Biochemistry, Faculty of Science, University of Dschang, PO. Box 67, Dschang, Cameroon.
Magang MEK; Molecular Parasitology and Entomology Unit, Department of Biochemistry, Faculty of Science, University of Dschang, PO. Box 67, Dschang, Cameroon.
Tume C; University of Dschang Faculty of Sciences, Dschang, Cameroon.
Tiofack AAZ; Molecular Parasitology and Entomology Unit, Department of Biochemistry, Faculty of Science, University of Dschang, PO. Box 67, Dschang, Cameroon.
Ravel S; Institut de Recherche pour le Développement, UMR INTERTRYP, Montpellier, France.
Simo G; Molecular Parasitology and Entomology Unit, Department of Biochemistry, Faculty of Science, University of Dschang, PO. Box 67, Dschang, Cameroon. Electronic address: .
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Źródło :
Veterinary parasitology, regional studies and reports [Vet Parasitol Reg Stud Reports] 2020 Apr; Vol. 20, pp. 100405. Date of Electronic Publication: 2020 Mar 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cattle Diseases/*parasitology
Diminazene/*analogs & derivatives
Drug Resistance/*genetics
Sheep Diseases/*parasitology
Trypanocidal Agents/*pharmacology
Trypanosoma congolense/*genetics
Trypanosomiasis, African/*veterinary
Animals ; Cameroon ; Cattle ; Cross-Sectional Studies ; Diminazene/pharmacology ; Sheep ; Sheep, Domestic ; Trypanosoma congolense/drug effects ; Trypanosoma congolense/isolation & purification ; Trypanosomiasis, African/parasitology
Czasopismo naukowe
Tytuł :
Serological and molecular detection of selected hemoprotozoan parasites in donkeys in West Omdurman, Khartoum State, Sudan.
Autorzy :
Elata A; National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Inada, Obihiro, Hokkaido 080-8555, Japan.; Department of Preventive Medicine and Public Health, Faculty of Veterinary Medicine, University of Khartoum, Khartoum, 13314, Sudan.
Mossaad E; Department of Pathology, Parasitology and Microbiology, College of Veterinary Medicine, Sudan University of Science and Technology, Khartoum, P.O. Box 204, Sudan.
Satti R; Department of Pathology, Parasitology and Microbiology, College of Veterinary Medicine, Sudan University of Science and Technology, Khartoum, P.O. Box 204, Sudan.
Matar N; Department of Pathology, Parasitology and Microbiology, College of Veterinary Medicine, Sudan University of Science and Technology, Khartoum, P.O. Box 204, Sudan.
Ohari Y; National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Inada, Obihiro, Hokkaido 080-8555, Japan.
Xuan X; National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Inada, Obihiro, Hokkaido 080-8555, Japan.
Inoue N; Obihiro University of Agriculture and Veterinary Medicine, Inada, Obihiro, Hokkaido 080-8555, Japan.
Suganuma K; National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Inada, Obihiro, Hokkaido 080-8555, Japan.
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Źródło :
The Journal of veterinary medical science [J Vet Med Sci] 2020 Mar 05; Vol. 82 (3), pp. 286-293. Date of Electronic Publication: 2020 Jan 22.
Typ publikacji :
Journal Article
MeSH Terms :
Babesiosis/*epidemiology
Equidae/*parasitology
Theileriasis/*epidemiology
Trypanosoma congolense/*isolation & purification
Trypanosomiasis, African/*veterinary
Animals ; Antibodies, Protozoan/blood ; Babesia/classification ; Babesiosis/blood ; Enzyme-Linked Immunosorbent Assay/veterinary ; Equidae/blood ; Sudan/epidemiology ; Theileria/classification ; Theileriasis/blood ; Trypanosomiasis, African/blood ; Trypanosomiasis, African/epidemiology
Czasopismo naukowe
Tytuł :
Hepatocyte-derived IL-10 plays a crucial role in attenuating pathogenicity during the chronic phase of T. congolense infection.
Autorzy :
Stijlemans B; Lab of Cellular and Molecular Immunology, Vrije Universiteit Brussel (VUB), Brussels, Belgium.; Myeloid Cell Immunology Lab, VIB Center for Inflammation Research, Brussels, Belgium.
Korf H; Laboratory of Hepatology, Department of Chronic Diseases, Metabolism and Ageing (CHROMETA), KU Leuven, Leuven, Belgium.
De Baetselier P; Lab of Cellular and Molecular Immunology, Vrije Universiteit Brussel (VUB), Brussels, Belgium.; Myeloid Cell Immunology Lab, VIB Center for Inflammation Research, Brussels, Belgium.
Brys L; Lab of Cellular and Molecular Immunology, Vrije Universiteit Brussel (VUB), Brussels, Belgium.; Myeloid Cell Immunology Lab, VIB Center for Inflammation Research, Brussels, Belgium.
Van Ginderachter JA; Lab of Cellular and Molecular Immunology, Vrije Universiteit Brussel (VUB), Brussels, Belgium.; Myeloid Cell Immunology Lab, VIB Center for Inflammation Research, Brussels, Belgium.
Magez S; Lab of Cellular and Molecular Immunology, Vrije Universiteit Brussel (VUB), Brussels, Belgium.; Laboratory for Biomedical Research, Ghent University Global Campus, Incheon, South Korea.
De Trez C; Lab of Cellular and Molecular Immunology, Vrije Universiteit Brussel (VUB), Brussels, Belgium.
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Źródło :
PLoS pathogens [PLoS Pathog] 2020 Feb 03; Vol. 16 (2), pp. e1008170. Date of Electronic Publication: 2020 Feb 03 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Hepatocytes*/immunology
Hepatocytes*/parasitology
Hepatocytes*/pathology
Immune Evasion*
Trypanosoma congolense*/immunology
Trypanosoma congolense*/pathogenicity
Trypanosomiasis, African*/immunology
Trypanosomiasis, African*/pathology
Interleukin-10/*immunology
Animals ; B-Lymphocytes/immunology ; B-Lymphocytes/pathology ; Chronic Disease ; Disease Models, Animal ; Female ; Killer Cells, Natural/immunology ; Killer Cells, Natural/pathology ; Lymphocyte Activation ; Mice ; Monocytes/immunology ; Monocytes/pathology ; T-Lymphocytes/immunology ; T-Lymphocytes/pathology
Czasopismo naukowe
Tytuł :
Effect of vegetable oils on the experimental infection of mice with Trypanosoma congolense.
Autorzy :
Kume A; National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Nishi 2-13, Inada-cho, Obihiro, Hokkaido, 080-8555, Japan.
Suganuma K; National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Nishi 2-13, Inada-cho, Obihiro, Hokkaido, 080-8555, Japan.
Umemiya-Shirafuji R; National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Nishi 2-13, Inada-cho, Obihiro, Hokkaido, 080-8555, Japan.
Suzuki H; National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Nishi 2-13, Inada-cho, Obihiro, Hokkaido, 080-8555, Japan. Electronic address: .
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Źródło :
Experimental parasitology [Exp Parasitol] 2020 Mar; Vol. 210, pp. 107845. Date of Electronic Publication: 2020 Jan 28.
Typ publikacji :
Journal Article
MeSH Terms :
Plant Oils/*administration & dosage
Trypanosoma congolense/*drug effects
Trypanosomiasis, African/*diet therapy
Animals ; Body Weight/drug effects ; Coconut Oil/administration & dosage ; Coconut Oil/chemistry ; Coconut Oil/pharmacology ; Energy Intake/drug effects ; Linoleic Acid/analysis ; Male ; Mice ; Mice, Inbred C57BL ; Oleic Acid/analysis ; Olive Oil/administration & dosage ; Olive Oil/chemistry ; Olive Oil/pharmacology ; Parasitemia/prevention & control ; Plant Oils/classification ; Plant Oils/pharmacology ; Plant Oils/therapeutic use ; Safflower Oil/administration & dosage ; Safflower Oil/chemistry ; Safflower Oil/pharmacology ; Trypanosomiasis, African/prevention & control
Czasopismo naukowe
Tytuł :
Expression, purification and characterisation of Trypanosoma congolense metacaspase 5 (TcoMCA5) - a potential drug target for animal African trypanosomiasis.
Autorzy :
Eyssen LE; Biochemistry, School of Life Sciences, University of KwaZulu-Natal (Pietermaritzburg Campus), Private Bag X01, Scottsville, 3209, South Africa.
Coetzer THT; Biochemistry, School of Life Sciences, University of KwaZulu-Natal (Pietermaritzburg Campus), Private Bag X01, Scottsville, 3209, South Africa. Electronic address: .
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Źródło :
Protein expression and purification [Protein Expr Purif] 2019 Dec; Vol. 164, pp. 105465. Date of Electronic Publication: 2019 Aug 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Trypanosoma congolense/*enzymology
Trypanosomiasis, African/*parasitology
Animals ; Cloning, Molecular ; Gelatinases/genetics ; Gelatinases/isolation & purification ; Gelatinases/metabolism ; Humans ; Mice, Inbred BALB C ; Recombinant Proteins/genetics ; Recombinant Proteins/isolation & purification ; Recombinant Proteins/metabolism ; Substrate Specificity ; Trypanosoma congolense/genetics ; Trypanosoma congolense/metabolism ; Trypanosomiasis, African/drug therapy
Czasopismo naukowe
Tytuł :
Host Immune Responses and Immune Evasion Strategies in African Trypanosomiasis.
Autorzy :
Onyilagha C; Department of Immunology, Rady Faculty of Health Sciences, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB, Canada.
Uzonna JE; Department of Immunology, Rady Faculty of Health Sciences, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB, Canada.; Department of Medical Microbiology, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, MB, Canada.
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Źródło :
Frontiers in immunology [Front Immunol] 2019 Nov 22; Vol. 10, pp. 2738. Date of Electronic Publication: 2019 Nov 22 (Print Publication: 2019).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Immune Evasion*
Macrophages/*immunology
Myeloid-Derived Suppressor Cells/*immunology
T-Lymphocytes, Regulatory/*immunology
Trypanosoma congolense/*immunology
Trypanosomiasis, African/*immunology
Animals ; Humans ; Protozoan Vaccines/immunology ; Protozoan Vaccines/therapeutic use ; Trypanosomiasis, African/prevention & control
Czasopismo naukowe
Tytuł :
Trypanostatic activity of geranylacetone: Mitigation of Trypanosoma congolense-associated pathological pertubations and insight into the mechanism of anaemia amelioration using in vitro and in silico models.
Autorzy :
Saad SB; Department of Biochemistry, Ahmadu Bello University, Zaria, Nigeria; Department of Biochemistry, Yusuf Maitama Sule University, Kano, Nigeria.
Ibrahim MA; Department of Biochemistry, Ahmadu Bello University, Zaria, Nigeria. Electronic address: .
Jatau ID; Department of Veterinary Parasitology and Entomology, Ahmadu Bello University, Zaria, Nigeria.
Shuaibu MN; Department of Biochemistry, Ahmadu Bello University, Zaria, Nigeria.
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Źródło :
Experimental parasitology [Exp Parasitol] 2019 Jun; Vol. 201, pp. 49-56. Date of Electronic Publication: 2019 Apr 25.
Typ publikacji :
Journal Article
MeSH Terms :
Anemia/*prevention & control
Terpenes/*pharmacology
Trypanocidal Agents/*pharmacology
Trypanosoma congolense/*drug effects
Trypanosomiasis, African/*drug therapy
Anemia/drug therapy ; Anemia/parasitology ; Animals ; Female ; Heart/drug effects ; Heart/parasitology ; Inhibitory Concentration 50 ; Kidney/drug effects ; Kidney/parasitology ; Kidney/pathology ; Liver/drug effects ; Liver/parasitology ; Liver/pathology ; Male ; Neglected Diseases/drug therapy ; Neglected Diseases/parasitology ; Neuraminidase/antagonists & inhibitors ; Neuraminidase/chemistry ; Organ Size/drug effects ; Random Allocation ; Rats ; Rats, Wistar ; Rubiaceae/chemistry ; Spleen/drug effects ; Spleen/parasitology ; Spleen/pathology ; Terpenes/chemistry ; Terpenes/therapeutic use ; Trypanocidal Agents/chemistry ; Trypanocidal Agents/therapeutic use ; Trypanosoma congolense/enzymology ; Trypanosomiasis, African/complications ; Trypanosomiasis, African/parasitology
Czasopismo naukowe
Tytuł :
Route of inoculation influences Trypanosoma congolense and Trypanosoma brucei brucei virulence in Swiss white mice.
Autorzy :
Ndungu K; Biotechnology Research Institute, Kenya Agricultural and Livestock Research Organization, Kikuyu, Kenya.
Thungu D; Biotechnology Research Institute, Kenya Agricultural and Livestock Research Organization, Kikuyu, Kenya.
Wamwiri F; Biotechnology Research Institute, Kenya Agricultural and Livestock Research Organization, Kikuyu, Kenya.
Mireji P; Biotechnology Research Institute, Kenya Agricultural and Livestock Research Organization, Kikuyu, Kenya.; Centre for Geographic Medicine Research-Coast, Kenya Medical Research Institute, Kilifi, Kenya.
Ngae G; Food Crops Research Institute, Kenya Agricultural and Livestock Research Organization, Nairobi, Kenya.
Gitonga P; Biotechnology Research Institute, Kenya Agricultural and Livestock Research Organization, Kikuyu, Kenya.
Mulinge J; Kenya Methodist University, Nairobi, Kenya.
Auma J; Biotechnology Research Institute, Kenya Agricultural and Livestock Research Organization, Kikuyu, Kenya.
Thuita J; Meru University of Science and Technology, Meru, Kenya.
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Źródło :
PloS one [PLoS One] 2019 Jun 20; Vol. 14 (6), pp. e0218441. Date of Electronic Publication: 2019 Jun 20 (Print Publication: 2019).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Parasitemia/*parasitology
Trypanosoma brucei brucei/*pathogenicity
Trypanosoma congolense/*pathogenicity
Trypanosomiasis, African/*parasitology
Animals ; Disease Models, Animal ; Humans ; Mice ; Parasitemia/transmission ; Trypanosomiasis, African/transmission ; Vaccination ; Virulence
Czasopismo naukowe
Tytuł :
Trypanosome infection rate in Glossina tachinoides: infested rivers of Limmu Kosa District Jimma Zone, Western Ethiopia.
Autorzy :
Meharenet B; National Institute for Control and Eradication of Tsetse Fly and Trypanosomosis, Kaliti Tsetse Fly Mass Rearing and Irradiation Center, P.O. Box: 19917, Addis Ababa, Ethiopia. .
Alemu D; Bedele Tsetse Fly and Trypanosomosis Control and Investigation Center, Bedele, Ethiopia.
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Źródło :
BMC research notes [BMC Res Notes] 2020 Mar 05; Vol. 13 (1), pp. 133. Date of Electronic Publication: 2020 Mar 05.
Typ publikacji :
Journal Article
MeSH Terms :
Insect Vectors/*parasitology
Trypanosoma congolense/*isolation & purification
Trypanosoma vivax/*isolation & purification
Tsetse Flies/*parasitology
Animals ; Cattle ; Cattle Diseases/epidemiology ; Cattle Diseases/transmission ; Cross-Sectional Studies ; Ethiopia/epidemiology ; Female ; Humans ; Male ; Population Density ; Trypanosomiasis, African/epidemiology ; Trypanosomiasis, African/transmission
Czasopismo naukowe
Tytuł :
Colonization of the tsetse fly midgut with commensal Kosakonia cowanii Zambiae inhibits trypanosome infection establishment.
Autorzy :
Weiss BL; Yale School of Public Health, Department of Epidemiology of Microbial Diseases, New Haven, Connecticut, United States of America.
Maltz MA; Southern Connecticut State University, New Haven, Connecticut, United States of America.
Vigneron A; Yale School of Public Health, Department of Epidemiology of Microbial Diseases, New Haven, Connecticut, United States of America.
Wu Y; Yale School of Public Health, Department of Epidemiology of Microbial Diseases, New Haven, Connecticut, United States of America.
Walter KS; Yale School of Public Health, Department of Epidemiology of Microbial Diseases, New Haven, Connecticut, United States of America.
O'Neill MB; Yale School of Public Health, Department of Epidemiology of Microbial Diseases, New Haven, Connecticut, United States of America.
Wang J; Yale School of Public Health, Department of Epidemiology of Microbial Diseases, New Haven, Connecticut, United States of America.
Aksoy S; Yale School of Public Health, Department of Epidemiology of Microbial Diseases, New Haven, Connecticut, United States of America.
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Źródło :
PLoS pathogens [PLoS Pathog] 2019 Feb 28; Vol. 15 (2), pp. e1007470. Date of Electronic Publication: 2019 Feb 28 (Print Publication: 2019).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Trypanosoma brucei brucei/*pathogenicity
Trypanosoma congolense/*pathogenicity
Trypanosomiasis, African/*prevention & control
Tsetse Flies/*microbiology
Tsetse Flies/*parasitology
Adult ; Africa South of the Sahara ; Animals ; Anopheles/microbiology ; Enterobacteriaceae ; Female ; Humans ; Male ; Mosquito Vectors/microbiology ; Mosquito Vectors/parasitology ; Symbiosis ; Trypanosomiasis, African/metabolism ; Trypanosomiasis, African/microbiology ; Trypanosomiasis, African/parasitology
Czasopismo naukowe
Tytuł :
Parasite specific 7SL-derived small RNA is an effective target for diagnosis of active trypanosomiasis infection.
Autorzy :
Chiweshe SM; The Roslin Institute, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian, United Kingdom.
Steketee PC; The Roslin Institute, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian, United Kingdom.
Jayaraman S; The Roslin Institute, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian, United Kingdom.
Paxton E; The Roslin Institute, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian, United Kingdom.
Neophytou K; Institute of Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom.
Erasmus H; Clinvet Research Innovation, Uitzich Road, Bainsvlei, Bloemfontein, South Africa.
Labuschagne M; Clinvet Research Innovation, Uitzich Road, Bainsvlei, Bloemfontein, South Africa.
Cooper A; Wellcome Centre for Molecular Parasitology, Institute of Biodiversity, Animal Health and Comparative Medicine, College of Medical, Veterinary & Life Sciences, Bearsden Road, University of Glasgow, Glasgow, United Kingdom.
MacLeod A; Wellcome Centre for Molecular Parasitology, Institute of Biodiversity, Animal Health and Comparative Medicine, College of Medical, Veterinary & Life Sciences, Bearsden Road, University of Glasgow, Glasgow, United Kingdom.
Grey FE; The Roslin Institute, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian, United Kingdom.
Morrison LJ; The Roslin Institute, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian, United Kingdom.
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Źródło :
PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2019 Feb 19; Vol. 13 (2), pp. e0007189. Date of Electronic Publication: 2019 Feb 19 (Print Publication: 2019).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cattle Diseases/*diagnosis
RNA, Small Cytoplasmic/*blood
Signal Recognition Particle/*blood
Trypanosoma brucei gambiense/*genetics
Trypanosoma congolense/*genetics
Trypanosomiasis, African/*veterinary
Trypanosomiasis, Bovine/*diagnosis
Animals ; Biomarkers/blood ; Cattle ; Cattle Diseases/parasitology ; Female ; Genome, Protozoan ; Male ; Molecular Diagnostic Techniques ; Real-Time Polymerase Chain Reaction ; Sequence Analysis, RNA ; Trypanocidal Agents/therapeutic use ; Trypanosoma brucei gambiense/drug effects ; Trypanosoma congolense/drug effects ; Trypanosomiasis, African/diagnosis ; Trypanosomiasis, African/drug therapy ; Trypanosomiasis, Bovine/drug therapy
Czasopismo naukowe
Tytuł :
How clonal is Trypanosoma congolense? A necessary clarification of the predominant clonal evolution model.
Autorzy :
Tibayrenc M; Maladies Infectieuses et Vecteurs Ecologie, Génétique, Evolution et Contrôle, MIVEGEC (IRD 224-CNRS 5290-UM1-UM2), Institut de recherche pour le développement, BP 64501, 34394 Montpellier Cedex 5, France. Electronic address: .
Ayala FJ; Department of Ecology and Evolutionary Biology, University of California, Irvine, CA, 92697, USA. Electronic address: .
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Źródło :
Acta tropica [Acta Trop] 2019 Feb; Vol. 190, pp. 28-29. Date of Electronic Publication: 2018 Nov 01.
Typ publikacji :
Letter; Comment
MeSH Terms :
Trypanosoma congolense*
Trypanosomiasis, African*
Animals ; Clonal Evolution ; Genomics ; Nucleic Acid Hybridization
Opinia redakcyjna
Tytuł :
Diminazene aceturate (Berenil) downregulates Trypanosoma congolense-induced proinflammatory cytokine production by altering phosphorylation of MAPK and STAT proteins.
Autorzy :
Kuriakose SM; Parasite Vaccines Development Laboratory, Department of Immunology, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, 750 McDermot Avenue, Winnipeg, MB, R3E 0T5, Canada.
Onyilagha C; Parasite Vaccines Development Laboratory, Department of Immunology, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, 750 McDermot Avenue, Winnipeg, MB, R3E 0T5, Canada.
Singh R; Parasite Vaccines Development Laboratory, Department of Immunology, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, 750 McDermot Avenue, Winnipeg, MB, R3E 0T5, Canada.
Jia P; Parasite Vaccines Development Laboratory, Department of Immunology, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, 750 McDermot Avenue, Winnipeg, MB, R3E 0T5, Canada.
Uzonna JE; Parasite Vaccines Development Laboratory, Department of Immunology, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, 750 McDermot Avenue, Winnipeg, MB, R3E 0T5, Canada. .
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Źródło :
Immunologic research [Immunol Res] 2019 Feb; Vol. 67 (1), pp. 84-92.
Typ publikacji :
Journal Article
MeSH Terms :
Diminazene/*analogs & derivatives
Macrophages/*immunology
Trypanocidal Agents/*therapeutic use
Trypanosoma congolense/*physiology
Trypanosomiasis, African/*drug therapy
Animals ; Cattle ; Cell Line, Transformed ; Cytokines/metabolism ; Diminazene/therapeutic use ; Female ; Humans ; Inflammation Mediators/metabolism ; Mice ; Mice, Inbred C57BL ; NF-kappa B/metabolism ; Phosphorylation ; STAT1 Transcription Factor/metabolism ; STAT3 Transcription Factor/metabolism ; Signal Transduction ; Trypanosomiasis, African/immunology ; p38 Mitogen-Activated Protein Kinases/metabolism
Czasopismo naukowe
Tytuł :
Structural and kinetic characterization of Trypanosoma congolense pyruvate kinase.
Autorzy :
Pinto Torres JE; Research Unit for Cellular and Molecular Immunology (CMIM), Vrije Universiteit Brussel, Pleinlaan 2, B-1050 Brussels, Belgium.
Yuan M; Centre for Translational and Chemical Biology, School of Biological Sciences, The University of Edinburgh, Michael Swann Building, The King's Buildings, Max Born Crescent, Edinburgh EH9 3BF, United Kingdom.
Goossens J; Research Unit for Cellular and Molecular Immunology (CMIM), Vrije Universiteit Brussel, Pleinlaan 2, B-1050 Brussels, Belgium.
Versées W; VIB-VUB Center for Structural Biology, Pleinlaan 2, 1050 Brussels, Belgium; Structural Biology Brussels, Vrije Universiteit Brussel, Pleinlaan 2, B-1050 Brussels, Belgium.
Caljon G; Laboratory of Microbiology, Parasitology and Hygiene (LMPH) and the Infla-Med Centre of Excellence, University of Antwerp, Campus Drie Eiken, Universiteitsplein 1, 2610 Wilrijk, Belgium.
Michels PA; Centre for Translational and Chemical Biology, School of Biological Sciences, The University of Edinburgh, Michael Swann Building, The King's Buildings, Max Born Crescent, Edinburgh EH9 3BF, United Kingdom.
Walkinshaw MD; Centre for Translational and Chemical Biology, School of Biological Sciences, The University of Edinburgh, Michael Swann Building, The King's Buildings, Max Born Crescent, Edinburgh EH9 3BF, United Kingdom.
Magez S; Research Unit for Cellular and Molecular Immunology (CMIM), Vrije Universiteit Brussel, Pleinlaan 2, B-1050 Brussels, Belgium; Ghent University Global Campus, Songdomunhwa-Ro 119, Yeonsu-Gu, 406-840 Incheon, South Korea.
Sterckx YG; Laboratory of Medical Biochemistry (LMB) and the Infla-Med Centre of Excellence, University of Antwerp, Campus Drie Eiken, Universiteitsplein 1, 2610 Wilrijk, Belgium. Electronic address: .
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Źródło :
Molecular and biochemical parasitology [Mol Biochem Parasitol] 2020 Mar; Vol. 236, pp. 111263. Date of Electronic Publication: 2020 Feb 19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Pyruvate Kinase*/chemistry
Pyruvate Kinase*/metabolism
Trypanosoma congolense/*metabolism
Animals ; Cattle ; Cattle Diseases/parasitology ; Humans ; Kinetics ; Models, Structural ; Protozoan Proteins/chemistry ; Protozoan Proteins/metabolism ; Trypanosomiasis, African/parasitology
Czasopismo naukowe
Tytuł :
Hybridization in Trypanosoma congolense does not challenge the predominant clonal evolution model. A comment on Tihon et al., 2017, Mol. Ecol.
Autorzy :
Tibayrenc M; Maladies Infectieuses et Vecteurs Ecologie, Génétique, Evolution et Contrôle, MIVEGEC (IRD 224-CNRS 5290-UM1-UM2), Institut de recherché pour le développement, Montpellier, France.
Ayala F; Department of Ecology and Evolutionary Biology, University of California at Irvine, Irvine, California.
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Źródło :
Molecular ecology [Mol Ecol] 2018 Sep; Vol. 27 (17), pp. 3421-3424.
Typ publikacji :
Journal Article; Comment
MeSH Terms :
Trypanosoma congolense*
Trypanosomiasis, African*
Animals ; Clonal Evolution ; Genomics ; Zambia
Czasopismo naukowe
Tytuł :
Mitonuclear genomics challenges the theory of clonality in Trypanosoma congolense: Reply to Tibayrenc and Ayala.
Autorzy :
Van den Broeck F; Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.
Tavernier LJM; Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.
Vermeiren L; Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.
Dujardin JC; Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.
Van Den Abbeele J; Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.
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Źródło :
Molecular ecology [Mol Ecol] 2018 Sep; Vol. 27 (17), pp. 3425-3431. Date of Electronic Publication: 2018 Aug 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Comment
MeSH Terms :
Trypanosoma congolense*
Trypanosomiasis, African*
Animals ; Clonal Evolution ; Genomics ; Zambia
Czasopismo naukowe
Tytuł :
The Structure of a Conserved Telomeric Region Associated with Variant Antigen Loci in the Blood Parasite Trypanosoma congolense.
Autorzy :
Abbas AH; Centre for Genomic Research, Biosciences Building, Liverpool, United Kingdom.; Department of Pathology, Faculty of Veterinary Medicine, University of Kufa, Najaf, Iraq.
Silva Pereira S; Department of Infection Biology, Institute of Infection and Global Health, University of Liverpool, United Kingdom.
D'Archivio S; School of Life Sciences, University of Nottingham, United Kingdom.
Wickstead B; School of Life Sciences, University of Nottingham, United Kingdom.
Morrison LJ; Department of Infection and Immunity, The Roslin Institute, Easter Bush, Edinburgh, United Kingdom.
Hall N; Earlham Institute, Norwich Research Park, Norwich, United Kingdom.
Hertz-Fowler C; Centre for Genomic Research, Biosciences Building, Liverpool, United Kingdom.
Darby AC; Centre for Genomic Research, Biosciences Building, Liverpool, United Kingdom.
Jackson AP; Department of Infection Biology, Institute of Infection and Global Health, University of Liverpool, United Kingdom.
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Źródło :
Genome biology and evolution [Genome Biol Evol] 2018 Sep 01; Vol. 10 (9), pp. 2458-2473. Date of Electronic Publication: 2018 Sep 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antigenic Variation*
Telomere/*genetics
Trypanosoma congolense/*genetics
Trypanosomiasis, African/*parasitology
Variant Surface Glycoproteins, Trypanosoma/*genetics
Animals ; Base Sequence ; Conserved Sequence ; DNA, Protozoan/genetics ; Evolution, Molecular ; Genes, Protozoan ; Phylogeny ; Protozoan Proteins/genetics ; Sequence Alignment ; Trypanosomiasis, African/veterinary
Czasopismo naukowe

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