Temat: "Trypanosomiasis, African" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Molecular epidemiology of Animal African Trypanosomosis in southwest Burkina Faso.
Autorzy:: Hounyèmè RE; Unité de recherche sur les maladies à vecteurs et biodiversité, Centre International of Recherche-Développement sur l'Élevage en zone Subhumide (CIRDES), Bobo-Dioulasso, Burkina Faso.; Département de Génétique et des Biotechnologies, Faculté des Sciences et Techniques (FAST), Université d'Abomey-Calavi, Cotonou, Bénin.
Kaboré J; Unité de recherche sur les maladies à vecteurs et biodiversité, Centre International of Recherche-Développement sur l'Élevage en zone Subhumide (CIRDES), Bobo-Dioulasso, Burkina Faso.; Unité de Formation et de Recherche Sciences et Techniques (UFR/ST), Université Nazi Boni, Bobo-Dioulasso, Burkina-Faso.
Gimonneau G; Unité de recherche sur les maladies à vecteurs et biodiversité, Centre International of Recherche-Développement sur l'Élevage en zone Subhumide (CIRDES), Bobo-Dioulasso, Burkina Faso.; INTERTRYP, Univ Montpellier, CIRAD, IRD, Montpellier, France.
Somda MB; Unité de recherche sur les maladies à vecteurs et biodiversité, Centre International of Recherche-Développement sur l'Élevage en zone Subhumide (CIRDES), Bobo-Dioulasso, Burkina Faso.; Unité de Formation et de Recherche Sciences et Techniques (UFR/ST), Université Nazi Boni, Bobo-Dioulasso, Burkina-Faso.
Salou E; Unité de recherche sur les maladies à vecteurs et biodiversité, Centre International of Recherche-Développement sur l'Élevage en zone Subhumide (CIRDES), Bobo-Dioulasso, Burkina Faso.; Institut du Développement Rural (IDR), Université Nazi Boni, Bobo-Dioulasso, Burkina-Faso.
Missihoun AA; Département de Génétique et des Biotechnologies, Faculté des Sciences et Techniques (FAST), Université d'Abomey-Calavi, Cotonou, Bénin.
Bengaly Z; Unité de recherche sur les maladies à vecteurs et biodiversité, Centre International of Recherche-Développement sur l'Élevage en zone Subhumide (CIRDES), Bobo-Dioulasso, Burkina Faso.
Jamonneau V; INTERTRYP, Univ Montpellier, CIRAD, IRD, Montpellier, France.
Boulangé A; Unité de recherche sur les maladies à vecteurs et biodiversité, Centre International of Recherche-Développement sur l'Élevage en zone Subhumide (CIRDES), Bobo-Dioulasso, Burkina Faso.; INTERTRYP, Univ Montpellier, CIRAD, IRD, Montpellier, France.; Pokaż więcej
Źródło:: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2022 Aug 22; Vol. 16 (8), pp. e0010106. Date of Electronic Publication: 2022 Aug 22 (Print Publication: 2022).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Trypanosoma*/genetics
Trypanosoma congolense*/genetics
Trypanosomiasis, African*/epidemiology
Trypanosomiasis, African*/parasitology
Trypanosomiasis, African*/veterinary
Tsetse Flies*/parasitology
Animals ; Burkina Faso/epidemiology ; Cattle ; Humans ; Insect Vectors/parasitology ; Molecular Epidemiology ; Swine ; Trypanosoma vivax/genetics

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Skocz do pozycji: 2.

Tytuł:: Free-ranging pigs identified as a multi-reservoir of Trypanosoma brucei and Trypanosoma congolense in the Vavoua area, a historical sleeping sickness focus of Côte d'Ivoire.
Autorzy:: Traoré BM; Laboratoire de Biodiversité et Gestion des Ecosystèmes Tropicaux, Unité de Recherche en Génétique et Epidémiologie Moléculaire, UFR Environnement, Université Jean Lorougnon Guédé, Daloa, Côte d'Ivoire.
Koffi M; Laboratoire de Biodiversité et Gestion des Ecosystèmes Tropicaux, Unité de Recherche en Génétique et Epidémiologie Moléculaire, UFR Environnement, Université Jean Lorougnon Guédé, Daloa, Côte d'Ivoire.
N'Djetchi MK; Laboratoire de Biodiversité et Gestion des Ecosystèmes Tropicaux, Unité de Recherche en Génétique et Epidémiologie Moléculaire, UFR Environnement, Université Jean Lorougnon Guédé, Daloa, Côte d'Ivoire.
Kaba D; Unité de Recherche « Trypanosomoses », Institut Pierre Richet, Bouaké, Côte d'Ivoire.
Kaboré J; Unité de Recherche sur les Maladies à Vecteurs et Biodiversité, Centre International de Recherche-Développement sur l'Elevage en zone Subhumide, Bobo-Dioulasso, Burkina Faso.
Ilboudo H; Unité de Recherche sur les Maladies à Vecteurs et Biodiversité, Centre International de Recherche-Développement sur l'Elevage en zone Subhumide, Bobo-Dioulasso, Burkina Faso.
Ahouty BA; Laboratoire de Biodiversité et Gestion des Ecosystèmes Tropicaux, Unité de Recherche en Génétique et Epidémiologie Moléculaire, UFR Environnement, Université Jean Lorougnon Guédé, Daloa, Côte d'Ivoire.
Koné M; Laboratoire de Biodiversité et Gestion des Ecosystèmes Tropicaux, Unité de Recherche en Génétique et Epidémiologie Moléculaire, UFR Environnement, Université Jean Lorougnon Guédé, Daloa, Côte d'Ivoire.; Unité de Recherche « Trypanosomoses », Institut Pierre Richet, Bouaké, Côte d'Ivoire.
Coulibaly B; Unité de Recherche « Trypanosomoses », Institut Pierre Richet, Bouaké, Côte d'Ivoire.
Konan T; Laboratoire de Biodiversité et Gestion des Ecosystèmes Tropicaux, Unité de Recherche en Génétique et Epidémiologie Moléculaire, UFR Environnement, Université Jean Lorougnon Guédé, Daloa, Côte d'Ivoire.
Segard A; Intertryp, IRD, Cirad, Université de Montpellier, Montpellier, France.
Kouakou L; Programme National d'Elimination de la Trypanosomiase Humaine Africaine, Abidjan, Côte d'Ivoire.
De Meeûs T; Intertryp, IRD, Cirad, Université de Montpellier, Montpellier, France.
Ravel S; Intertryp, IRD, Cirad, Université de Montpellier, Montpellier, France.
Solano P; Intertryp, IRD, Cirad, Université de Montpellier, Montpellier, France.
Bart JM; Intertryp, IRD, Cirad, Université de Montpellier, Montpellier, France.
Jamonneau V; Unité de Recherche « Trypanosomoses », Institut Pierre Richet, Bouaké, Côte d'Ivoire.; Intertryp, IRD, Cirad, Université de Montpellier, Montpellier, France.; Pokaż więcej
Źródło:: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2021 Dec 22; Vol. 15 (12), pp. e0010036. Date of Electronic Publication: 2021 Dec 22 (Print Publication: 2021).
Typ publikacji:: Journal Article
MeSH Terms:: Disease Reservoirs/*parasitology
Swine Diseases/*parasitology
Trypanosoma brucei gambiense/*isolation & purification
Trypanosoma congolense/*isolation & purification
Trypanosomiasis, African/*parasitology
Trypanosomiasis, African/*veterinary
Animals ; Animals, Domestic/parasitology ; Cote d'Ivoire/epidemiology ; Humans ; Polymerase Chain Reaction ; Swine ; Swine Diseases/epidemiology ; Trypanosoma brucei gambiense/genetics ; Trypanosoma brucei gambiense/physiology ; Trypanosoma congolense/genetics ; Trypanosoma congolense/physiology ; Trypanosomiasis, African/epidemiology

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Skocz do pozycji: 3.

Tytuł:: Veterinary trypanocidal benzoxaboroles are peptidase-activated prodrugs.
Autorzy:: Giordani F; Wellcome Centre for Integrative Parasitology, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom.
Paape D; Wellcome Centre for Integrative Parasitology, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom.
Vincent IM; Wellcome Centre for Integrative Parasitology, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom.
Pountain AW; Wellcome Centre for Integrative Parasitology, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom.
Fernández-Cortés F; Wellcome Centre for Integrative Parasitology, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom.
Rico E; Wellcome Centre for Anti-Infectives Research, School of Life Sciences, University of Dundee, Dundee, United Kingdom.
Zhang N; Wellcome Centre for Anti-Infectives Research, School of Life Sciences, University of Dundee, Dundee, United Kingdom.
Morrison LJ; Roslin Institute, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Midlothian, United Kingdom.
Freund Y; Anacor Pharmaceuticals, Inc., Palo Alto, California, United States of America.
Witty MJ; Global Alliance for Livestock and Veterinary Medicine, Pentlands Science Park, Penicuik, Edinburgh, United Kingdom.
Peter R; Global Alliance for Livestock and Veterinary Medicine, Pentlands Science Park, Penicuik, Edinburgh, United Kingdom.
Edwards DY; Wellcome Centre for Anti-Infectives Research, School of Life Sciences, University of Dundee, Dundee, United Kingdom.
Wilkes JM; Wellcome Centre for Integrative Parasitology, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom.
van der Hooft JJJ; Glasgow Polyomics, Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom.; Current address: Bioinformatics Group, Wageningen University, Wageningen, the Netherlands.
Regnault C; Glasgow Polyomics, Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom.
Read KD; Wellcome Centre for Anti-Infectives Research, School of Life Sciences, University of Dundee, Dundee, United Kingdom.
Horn D; Wellcome Centre for Anti-Infectives Research, School of Life Sciences, University of Dundee, Dundee, United Kingdom.
Field MC; Wellcome Centre for Anti-Infectives Research, School of Life Sciences, University of Dundee, Dundee, United Kingdom.; Institute of Parasitology, Biology Centre of the Czech Academy of Sciences, České Budějovice, Czech Republic.
Barrett MP; Wellcome Centre for Integrative Parasitology, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom.; Glasgow Polyomics, Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom.; Pokaż więcej
Źródło:: PLoS pathogens [PLoS Pathog] 2020 Nov 03; Vol. 16 (11), pp. e1008932. Date of Electronic Publication: 2020 Nov 03 (Print Publication: 2020).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Boron Compounds/*metabolism
Carboxypeptidases/*metabolism
Trypanocidal Agents/*metabolism
Trypanosoma brucei brucei/*enzymology
Trypanosoma congolense/*enzymology
Trypanosoma vivax/*enzymology
Trypanosomiasis, African/*veterinary
Valine/*analogs & derivatives
Animals ; Carboxylic Acids/metabolism ; Drug Resistance ; Female ; Livestock ; Mice ; Parasitemia/veterinary ; Prodrugs/metabolism ; Protozoan Proteins/metabolism ; Trypanosoma brucei brucei/drug effects ; Trypanosoma congolense/drug effects ; Trypanosoma vivax/drug effects ; Trypanosomiasis, African/drug therapy ; Trypanosomiasis, African/parasitology ; Valine/metabolism

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Skocz do pozycji: 4.

Tytuł:: Reliable, scalable functional genetics in bloodstream-form Trypanosoma congolense in vitro and in vivo.
Autorzy:: Awuah-Mensah G; School of Life Sciences, University of Nottingham, Nottingham, United Kingdom.
McDonald J; School of Life Sciences, University of Nottingham, Nottingham, United Kingdom.
Steketee PC; The Roslin Institute, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, United Kingdom.
Autheman D; Cell Surface Signalling Laboratory, Wellcome Sanger Institute, Cambridge, United Kingdom.
Whipple S; School of Life Sciences, University of Nottingham, Nottingham, United Kingdom.
D'Archivio S; School of Life Sciences, University of Nottingham, Nottingham, United Kingdom.
Brandt C; Pathogen Support Team, Wellcome Sanger Institute, Cambridge, United Kingdom.
Clare S; Pathogen Support Team, Wellcome Sanger Institute, Cambridge, United Kingdom.
Harcourt K; Pathogen Support Team, Wellcome Sanger Institute, Cambridge, United Kingdom.
Wright GJ; Cell Surface Signalling Laboratory, Wellcome Sanger Institute, Cambridge, United Kingdom.; Department of Biology, Hull York Medical School, York Biomedical Research Institute, University of York, York, United Kingdom.
Morrison LJ; The Roslin Institute, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, United Kingdom.
Gadelha C; School of Life Sciences, University of Nottingham, Nottingham, United Kingdom.
Wickstead B; School of Life Sciences, University of Nottingham, Nottingham, United Kingdom.; Pokaż więcej
Źródło:: PLoS pathogens [PLoS Pathog] 2021 Jan 22; Vol. 17 (1), pp. e1009224. Date of Electronic Publication: 2021 Jan 22 (Print Publication: 2021).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Genetics, Microbial*
Transgenes*
Protozoan Proteins/*genetics
Trypanosoma congolense/*genetics
Trypanosoma congolense/*pathogenicity
Trypanosomiasis, African/*parasitology
Animals ; Female ; Genome, Protozoan ; In Vitro Techniques ; Male ; Mice ; Mice, Inbred BALB C ; Trypanosomiasis, African/genetics

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Skocz do pozycji: 5.

Tytuł:: Hepatocyte-derived IL-10 plays a crucial role in attenuating pathogenicity during the chronic phase of T. congolense infection.
Autorzy:: Stijlemans B; Lab of Cellular and Molecular Immunology, Vrije Universiteit Brussel (VUB), Brussels, Belgium.; Myeloid Cell Immunology Lab, VIB Center for Inflammation Research, Brussels, Belgium.
Korf H; Laboratory of Hepatology, Department of Chronic Diseases, Metabolism and Ageing (CHROMETA), KU Leuven, Leuven, Belgium.
De Baetselier P; Lab of Cellular and Molecular Immunology, Vrije Universiteit Brussel (VUB), Brussels, Belgium.; Myeloid Cell Immunology Lab, VIB Center for Inflammation Research, Brussels, Belgium.
Brys L; Lab of Cellular and Molecular Immunology, Vrije Universiteit Brussel (VUB), Brussels, Belgium.; Myeloid Cell Immunology Lab, VIB Center for Inflammation Research, Brussels, Belgium.
Van Ginderachter JA; Lab of Cellular and Molecular Immunology, Vrije Universiteit Brussel (VUB), Brussels, Belgium.; Myeloid Cell Immunology Lab, VIB Center for Inflammation Research, Brussels, Belgium.
Magez S; Lab of Cellular and Molecular Immunology, Vrije Universiteit Brussel (VUB), Brussels, Belgium.; Laboratory for Biomedical Research, Ghent University Global Campus, Incheon, South Korea.
De Trez C; Lab of Cellular and Molecular Immunology, Vrije Universiteit Brussel (VUB), Brussels, Belgium.; Pokaż więcej
Źródło:: PLoS pathogens [PLoS Pathog] 2020 Feb 03; Vol. 16 (2), pp. e1008170. Date of Electronic Publication: 2020 Feb 03 (Print Publication: 2020).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Hepatocytes*/immunology
Hepatocytes*/parasitology
Hepatocytes*/pathology
Immune Evasion*
Trypanosoma congolense*/immunology
Trypanosoma congolense*/pathogenicity
Trypanosomiasis, African*/immunology
Trypanosomiasis, African*/pathology
Interleukin-10/*immunology
Animals ; B-Lymphocytes/immunology ; B-Lymphocytes/pathology ; Chronic Disease ; Disease Models, Animal ; Female ; Killer Cells, Natural/immunology ; Killer Cells, Natural/pathology ; Lymphocyte Activation ; Mice ; Monocytes/immunology ; Monocytes/pathology ; T-Lymphocytes/immunology ; T-Lymphocytes/pathology

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Skocz do pozycji: 6.

Tytuł:: Route of inoculation influences Trypanosoma congolense and Trypanosoma brucei brucei virulence in Swiss white mice.
Autorzy:: Ndungu K; Biotechnology Research Institute, Kenya Agricultural and Livestock Research Organization, Kikuyu, Kenya.
Thungu D; Biotechnology Research Institute, Kenya Agricultural and Livestock Research Organization, Kikuyu, Kenya.
Wamwiri F; Biotechnology Research Institute, Kenya Agricultural and Livestock Research Organization, Kikuyu, Kenya.
Mireji P; Biotechnology Research Institute, Kenya Agricultural and Livestock Research Organization, Kikuyu, Kenya.; Centre for Geographic Medicine Research-Coast, Kenya Medical Research Institute, Kilifi, Kenya.
Ngae G; Food Crops Research Institute, Kenya Agricultural and Livestock Research Organization, Nairobi, Kenya.
Gitonga P; Biotechnology Research Institute, Kenya Agricultural and Livestock Research Organization, Kikuyu, Kenya.
Mulinge J; Kenya Methodist University, Nairobi, Kenya.
Auma J; Biotechnology Research Institute, Kenya Agricultural and Livestock Research Organization, Kikuyu, Kenya.
Thuita J; Meru University of Science and Technology, Meru, Kenya.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2019 Jun 20; Vol. 14 (6), pp. e0218441. Date of Electronic Publication: 2019 Jun 20 (Print Publication: 2019).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Parasitemia/*parasitology
Trypanosoma brucei brucei/*pathogenicity
Trypanosoma congolense/*pathogenicity
Trypanosomiasis, African/*parasitology
Animals ; Disease Models, Animal ; Humans ; Mice ; Parasitemia/transmission ; Trypanosomiasis, African/transmission ; Vaccination ; Virulence

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Skocz do pozycji: 7.

Tytuł:: Divergent metabolism between Trypanosoma congolense and Trypanosoma brucei results in differential sensitivity to metabolic inhibition.
Autorzy:: Steketee PC; The Roslin Institute, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, United Kingdom.
Dickie EA; Wellcome Centre for Integrative Parasitology, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom.
Iremonger J; The Roslin Institute, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, United Kingdom.
Crouch K; Wellcome Centre for Integrative Parasitology, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom.
Paxton E; The Roslin Institute, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, United Kingdom.
Jayaraman S; The Roslin Institute, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, United Kingdom.
Alfituri OA; The Roslin Institute, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, United Kingdom.
Awuah-Mensah G; School of Life Sciences, University of Nottingham, Nottingham, United Kingdom.
Ritchie R; Wellcome Centre for Integrative Parasitology, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom.
Schnaufer A; Institute of Immunology and Infection Research, University of Edinburgh, Edinburgh, United Kingdom.
Rowan T; Global Alliance for Livestock Veterinary Medicines, Edinburgh, United Kingdom.
de Koning HP; Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom.
Gadelha C; School of Life Sciences, University of Nottingham, Nottingham, United Kingdom.
Wickstead B; School of Life Sciences, University of Nottingham, Nottingham, United Kingdom.
Barrett MP; Wellcome Centre for Integrative Parasitology, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom.; Glasgow Polyomics, University of Glasgow, Glasgow, United Kingdom.
Morrison LJ; The Roslin Institute, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, United Kingdom.; Pokaż więcej
Źródło:: PLoS pathogens [PLoS Pathog] 2021 Jul 26; Vol. 17 (7), pp. e1009734. Date of Electronic Publication: 2021 Jul 26 (Print Publication: 2021).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Trypanosoma brucei brucei/*metabolism
Trypanosoma congolense/*metabolism
Animals ; Lipid Regulating Agents/pharmacology ; Mice ; Trypanosoma brucei brucei/drug effects ; Trypanosoma congolense/drug effects ; Trypanosomiasis, African

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Skocz do pozycji: 8.

Tytuł:: Colonization of the tsetse fly midgut with commensal Kosakonia cowanii Zambiae inhibits trypanosome infection establishment.
Autorzy:: Weiss BL; Yale School of Public Health, Department of Epidemiology of Microbial Diseases, New Haven, Connecticut, United States of America.
Maltz MA; Southern Connecticut State University, New Haven, Connecticut, United States of America.
Vigneron A; Yale School of Public Health, Department of Epidemiology of Microbial Diseases, New Haven, Connecticut, United States of America.
Wu Y; Yale School of Public Health, Department of Epidemiology of Microbial Diseases, New Haven, Connecticut, United States of America.
Walter KS; Yale School of Public Health, Department of Epidemiology of Microbial Diseases, New Haven, Connecticut, United States of America.
O'Neill MB; Yale School of Public Health, Department of Epidemiology of Microbial Diseases, New Haven, Connecticut, United States of America.
Wang J; Yale School of Public Health, Department of Epidemiology of Microbial Diseases, New Haven, Connecticut, United States of America.
Aksoy S; Yale School of Public Health, Department of Epidemiology of Microbial Diseases, New Haven, Connecticut, United States of America.; Pokaż więcej
Źródło:: PLoS pathogens [PLoS Pathog] 2019 Feb 28; Vol. 15 (2), pp. e1007470. Date of Electronic Publication: 2019 Feb 28 (Print Publication: 2019).
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Trypanosoma brucei brucei/*pathogenicity
Trypanosoma congolense/*pathogenicity
Trypanosomiasis, African/*prevention & control
Tsetse Flies/*microbiology
Tsetse Flies/*parasitology
Adult ; Africa South of the Sahara ; Animals ; Anopheles/microbiology ; Enterobacteriaceae ; Female ; Humans ; Male ; Mosquito Vectors/microbiology ; Mosquito Vectors/parasitology ; Symbiosis ; Trypanosomiasis, African/metabolism ; Trypanosomiasis, African/microbiology ; Trypanosomiasis, African/parasitology

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Skocz do pozycji: 9.

Tytuł:: Parasite specific 7SL-derived small RNA is an effective target for diagnosis of active trypanosomiasis infection.
Autorzy:: Chiweshe SM; The Roslin Institute, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian, United Kingdom.
Steketee PC; The Roslin Institute, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian, United Kingdom.
Jayaraman S; The Roslin Institute, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian, United Kingdom.
Paxton E; The Roslin Institute, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian, United Kingdom.
Neophytou K; Institute of Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom.
Erasmus H; Clinvet Research Innovation, Uitzich Road, Bainsvlei, Bloemfontein, South Africa.
Labuschagne M; Clinvet Research Innovation, Uitzich Road, Bainsvlei, Bloemfontein, South Africa.
Cooper A; Wellcome Centre for Molecular Parasitology, Institute of Biodiversity, Animal Health and Comparative Medicine, College of Medical, Veterinary & Life Sciences, Bearsden Road, University of Glasgow, Glasgow, United Kingdom.
MacLeod A; Wellcome Centre for Molecular Parasitology, Institute of Biodiversity, Animal Health and Comparative Medicine, College of Medical, Veterinary & Life Sciences, Bearsden Road, University of Glasgow, Glasgow, United Kingdom.
Grey FE; The Roslin Institute, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian, United Kingdom.
Morrison LJ; The Roslin Institute, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian, United Kingdom.; Pokaż więcej
Źródło:: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2019 Feb 19; Vol. 13 (2), pp. e0007189. Date of Electronic Publication: 2019 Feb 19 (Print Publication: 2019).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Cattle Diseases/*diagnosis
RNA, Small Cytoplasmic/*blood
Signal Recognition Particle/*blood
Trypanosoma brucei gambiense/*genetics
Trypanosoma congolense/*genetics
Trypanosomiasis, African/*veterinary
Trypanosomiasis, Bovine/*diagnosis
Animals ; Biomarkers/blood ; Cattle ; Cattle Diseases/parasitology ; Female ; Genome, Protozoan ; Male ; Molecular Diagnostic Techniques ; Real-Time Polymerase Chain Reaction ; Sequence Analysis, RNA ; Trypanocidal Agents/therapeutic use ; Trypanosoma brucei gambiense/drug effects ; Trypanosoma congolense/drug effects ; Trypanosomiasis, African/diagnosis ; Trypanosomiasis, African/drug therapy ; Trypanosomiasis, Bovine/drug therapy

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Skocz do pozycji: 10.

Tytuł:: Structural basis for the high specificity of a Trypanosoma congolense immunoassay targeting glycosomal aldolase.
Autorzy:: Pinto J; Research Unit for Cellular and Molecular Immunology (CMIM), Vrije Universiteit Brussel (VUB), Brussels, Belgium.; Structural Biology Research Centre, VIB, Brussels, Belgium.
Odongo S; Department of Biotechnical and Diagnostic Sciences, College of Veterinary Medicine, Animal Resources and Bio-security (COVAB), Makerere University, Kampala, Uganda.
Lee F; Research Unit for Cellular and Molecular Immunology (CMIM), Vrije Universiteit Brussel (VUB), Brussels, Belgium.
Gaspariunaite V; Research Unit for Cellular and Molecular Immunology (CMIM), Vrije Universiteit Brussel (VUB), Brussels, Belgium.
Muyldermans S; Research Unit for Cellular and Molecular Immunology (CMIM), Vrije Universiteit Brussel (VUB), Brussels, Belgium.
Magez S; Research Unit for Cellular and Molecular Immunology (CMIM), Vrije Universiteit Brussel (VUB), Brussels, Belgium.; Structural Biology Research Centre, VIB, Brussels, Belgium.; Ghent Universtiy Global Campus, Yeonsu-Gu, Incheon, South Korea.
Sterckx YG; Research Unit for Cellular and Molecular Immunology (CMIM), Vrije Universiteit Brussel (VUB), Brussels, Belgium.; Structural Biology Research Centre, VIB, Brussels, Belgium.; Pokaż więcej
Źródło:: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2017 Sep 15; Vol. 11 (9), pp. e0005932. Date of Electronic Publication: 2017 Sep 15 (Print Publication: 2017).
Typ publikacji:: Journal Article
MeSH Terms:: Immunoassay*
Fructose-Bisphosphate Aldolase/*analysis
Trypanosoma congolense/*enzymology
Trypanosoma congolense/*immunology
Trypanosomiasis, African/*veterinary
Trypanosomiasis, Bovine/*diagnosis
Africa South of the Sahara/epidemiology ; Animals ; Antigens, Protozoan/analysis ; Antigens, Protozoan/immunology ; Cattle ; Crystallography, X-Ray ; Enzyme-Linked Immunosorbent Assay ; Fructose-Bisphosphate Aldolase/chemistry ; Fructose-Bisphosphate Aldolase/genetics ; Fructose-Bisphosphate Aldolase/immunology ; Mutagenesis, Site-Directed ; Sensitivity and Specificity ; Single-Domain Antibodies/chemistry ; Single-Domain Antibodies/immunology ; Trypanosoma congolense/chemistry ; Trypanosomiasis, African/diagnosis ; Trypanosomiasis, African/epidemiology ; Trypanosomiasis, African/parasitology

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Skocz do pozycji: 11.

Tytuł:: MIF-Mediated Hemodilution Promotes Pathogenic Anemia in Experimental African Trypanosomosis.
Autorzy:: Stijlemans B; Laboratory of Cellular and Molecular Immunology, Vrije Universiteit Brussel (VUB), Brussels, Belgium.; Lab of Myeloid Cell Immunology, VIB Inflammation Research Center, Ghent, Belgium.
Brys L; Laboratory of Cellular and Molecular Immunology, Vrije Universiteit Brussel (VUB), Brussels, Belgium.; Lab of Myeloid Cell Immunology, VIB Inflammation Research Center, Ghent, Belgium.
Korf H; Translational Research Center for Gastrointestinal Disorders (TARGID), Department of Clinical and Experimental Medicine, KU Leuven, Leuven, Belgium.
Bieniasz-Krzywiec P; VIB Vesalius Research Center, University of Leuven (KUL), Leuven, Belgium.
Sparkes A; Laboratory of Cellular and Molecular Immunology, Vrije Universiteit Brussel (VUB), Brussels, Belgium.; Lab of Myeloid Cell Immunology, VIB Inflammation Research Center, Ghent, Belgium.
Vansintjan L; Laboratory of Cellular and Molecular Immunology, Vrije Universiteit Brussel (VUB), Brussels, Belgium.; Lab of Myeloid Cell Immunology, VIB Inflammation Research Center, Ghent, Belgium.
Leng L; Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, United States of America.
Vanbekbergen N; Laboratorium Cellulaire Genetica (CEGE), Vrije Universiteit Brussel (VUB), Brussels, Belgium.
Mazzone M; VIB Vesalius Research Center, University of Leuven (KUL), Leuven, Belgium.
Caljon G; Laboratory for Microbiology, Parasitology and Hygiene (LMPH), University of Antwerp, Wilrijk, Belgium.; Unit of Veterinary Protozoology, Department of Biomedical Sciences, Institute of Tropical Medicine Antwerp (ITM), Antwerp, Belgium.
Van Den Abbeele J; Unit of Veterinary Protozoology, Department of Biomedical Sciences, Institute of Tropical Medicine Antwerp (ITM), Antwerp, Belgium.
Odongo S; Laboratory of Cellular and Molecular Immunology, Vrije Universiteit Brussel (VUB), Brussels, Belgium.; Department of Structural Biology, Vrije Universiteit Brussel, Brussels, Belgium.
De Trez C; Laboratory of Cellular and Molecular Immunology, Vrije Universiteit Brussel (VUB), Brussels, Belgium.; Department of Structural Biology, Vrije Universiteit Brussel, Brussels, Belgium.
Magez S; Laboratory of Cellular and Molecular Immunology, Vrije Universiteit Brussel (VUB), Brussels, Belgium.; Department of Structural Biology, Vrije Universiteit Brussel, Brussels, Belgium.; Laboratory for Biomedical Research, Ghent University Global Campus, Yeonsu-Gu, Incheon, South Korea.
Van Ginderachter JA; Laboratory of Cellular and Molecular Immunology, Vrije Universiteit Brussel (VUB), Brussels, Belgium.; Lab of Myeloid Cell Immunology, VIB Inflammation Research Center, Ghent, Belgium.
Beschin A; Laboratory of Cellular and Molecular Immunology, Vrije Universiteit Brussel (VUB), Brussels, Belgium.; Lab of Myeloid Cell Immunology, VIB Inflammation Research Center, Ghent, Belgium.
Bucala R; Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, United States of America.
De Baetselier P; Laboratory of Cellular and Molecular Immunology, Vrije Universiteit Brussel (VUB), Brussels, Belgium.; Lab of Myeloid Cell Immunology, VIB Inflammation Research Center, Ghent, Belgium.; Pokaż więcej
Źródło:: PLoS pathogens [PLoS Pathog] 2016 Sep 15; Vol. 12 (9), pp. e1005862. Date of Electronic Publication: 2016 Sep 15 (Print Publication: 2016).
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Erythropoiesis*
Hematopoiesis, Extramedullary*
Anemia/*metabolism
Intramolecular Oxidoreductases/*metabolism
Macrophage Migration-Inhibitory Factors/*metabolism
Trypanosoma congolense/*metabolism
Trypanosomiasis, African/*metabolism
Anemia/genetics ; Anemia/parasitology ; Anemia/pathology ; Animals ; Bone Marrow/metabolism ; Bone Marrow/parasitology ; Bone Marrow/pathology ; Cattle ; Disease Models, Animal ; Erythrocytes/metabolism ; Erythrocytes/parasitology ; Erythrocytes/pathology ; Hemodilution ; Humans ; Intramolecular Oxidoreductases/genetics ; Macrophage Migration-Inhibitory Factors/genetics ; Mice ; Mice, Knockout ; Spleen/metabolism ; Spleen/parasitology ; Spleen/pathology ; Thrombocytopenia/genetics ; Thrombocytopenia/metabolism ; Thrombocytopenia/parasitology ; Thrombocytopenia/pathology ; Trypanosomiasis, African/genetics ; Trypanosomiasis, African/pathology

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Skocz do pozycji: 12.

Tytuł:: An Anti-proteome Nanobody Library Approach Yields a Specific Immunoassay for Trypanosoma congolense Diagnosis Targeting Glycosomal Aldolase.
Autorzy:: Odongo S; Laboratory of Cellular and Molecular Immunology (CMIM), Vrije Universiteit Brussel, Brussels, Belgium.; Structural Biology Research Center, Vlaams Instituut voor Biotechnologie (VIB), Brussels, Belgium.; Department of Biotechnical and Diagnostic Sciences, College of Veterinary Medicine, Animal Resources and Bio-security (COVAB), Makerere University, Kampala, Uganda.
Sterckx YG; Laboratory of Cellular and Molecular Immunology (CMIM), Vrije Universiteit Brussel, Brussels, Belgium.; Structural Biology Research Center, Vlaams Instituut voor Biotechnologie (VIB), Brussels, Belgium.
Stijlemans B; Laboratory of Cellular and Molecular Immunology (CMIM), Vrije Universiteit Brussel, Brussels, Belgium.; Laboratory of Myeloid Cell Immunology, VIB Inflammation Research Center, Ghent, Belgium.
Pillay D; Microbiologie Fondamentale et Pathogénicité, Centre National de la Recherche Scientifique, Université Bordeaux, Bordeaux, France.
Baltz T; Microbiologie Fondamentale et Pathogénicité, Centre National de la Recherche Scientifique, Université Bordeaux, Bordeaux, France.
Muyldermans S; Laboratory of Cellular and Molecular Immunology (CMIM), Vrije Universiteit Brussel, Brussels, Belgium.
Magez S; Laboratory of Cellular and Molecular Immunology (CMIM), Vrije Universiteit Brussel, Brussels, Belgium.; Structural Biology Research Center, Vlaams Instituut voor Biotechnologie (VIB), Brussels, Belgium.; Pokaż więcej
Źródło:: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2016 Feb 02; Vol. 10 (2), pp. e0004420. Date of Electronic Publication: 2016 Feb 02 (Print Publication: 2016).
Typ publikacji:: Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Antibodies, Protozoan/*analysis
Antigens, Protozoan/*analysis
Enzyme-Linked Immunosorbent Assay/*methods
Fructose-Bisphosphate Aldolase/*analysis
Proteome/*immunology
Trypanosoma congolense/*enzymology
Trypanosomiasis, African/*diagnosis
Animals ; Antibodies, Protozoan/genetics ; Antibodies, Protozoan/immunology ; Antigens, Protozoan/genetics ; Antigens, Protozoan/immunology ; Fructose-Bisphosphate Aldolase/genetics ; Fructose-Bisphosphate Aldolase/immunology ; Gene Library ; Humans ; Mice ; Mice, Inbred C57BL ; Proteome/analysis ; Proteome/genetics ; Trypanosoma congolense/genetics ; Trypanosoma congolense/immunology ; Trypanosoma congolense/isolation & purification ; Trypanosomiasis, African/immunology ; Trypanosomiasis, African/parasitology

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Skocz do pozycji: 13.

Tytuł:: A comparison of phenotypic traits related to trypanotolerance in five west african cattle breeds highlights the value of shorthorn taurine breeds.
Autorzy:: Berthier D; CIRAD, UMR INTERTRYP, F-34398, Montpellier, France.
Peylhard M; CIRAD, UMR INTERTRYP, F-34398, Montpellier, France; CIRDES, 01 BP 454 Bobo-Dioulasso 01, Burkina Faso.
Dayo GK; CIRDES, 01 BP 454 Bobo-Dioulasso 01, Burkina Faso.
Flori L; CIRAD, UMR INTERTRYP, F-34398, Montpellier, France; INRA, UMR 1313 GABI, F-78350, Jouy-en-Josas, France.
Sylla S; CIRDES, 01 BP 454 Bobo-Dioulasso 01, Burkina Faso.
Bolly S; CIRDES, 01 BP 454 Bobo-Dioulasso 01, Burkina Faso.
Sakande H; CIRDES, 01 BP 454 Bobo-Dioulasso 01, Burkina Faso.
Chantal I; CIRAD, UMR INTERTRYP, F-34398, Montpellier, France.
Thevenon S; CIRAD, UMR INTERTRYP, F-34398, Montpellier, France.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2015 May 08; Vol. 10 (5), pp. e0126498. Date of Electronic Publication: 2015 May 08 (Print Publication: 2015).
Typ publikacji:: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Cattle*/genetics
Cattle*/parasitology
Cattle*/physiology
Cattle Diseases*/genetics
Cattle Diseases*/parasitology
Trypanosoma congolense*/isolation & purification
Trypanosomiasis, African*/genetics
Trypanosomiasis, African*/parasitology
Trypanosomiasis, African*/veterinary
Animals ; Male ; Africa South of the Sahara ; Breeding ; Genome ; Phenotype ; Transcriptome

Czasopismo naukowe

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Pełny tekst Szczegóły

Skocz do pozycji: 14.

Tytuł:: The B cell adaptor molecule Bam32 is critically important for optimal antibody response and resistance to Trypanosoma congolense infection in mice.
Autorzy:: Onyilagha C; Department of Immunology, Faculty of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.
Jia P; Department of Immunology, Faculty of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.
Jayachandran N; Department of Immunology, Faculty of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.
Hou S; Department of Immunology, Faculty of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.
Okwor I; Department of Medical Microbiology, Faculty of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.
Kuriakose S; Department of Immunology, Faculty of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.
Marshall A; Department of Immunology, Faculty of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.
Uzonna JE; Department of Immunology, Faculty of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada; Department of Medical Microbiology, Faculty of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.; Pokaż więcej
Źródło:: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2015 Apr 13; Vol. 9 (4), pp. e0003716. Date of Electronic Publication: 2015 Apr 13 (Print Publication: 2015).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Adaptor Proteins, Signal Transducing/*metabolism
Lipoproteins/*metabolism
Trypanosoma congolense/*immunology
Trypanosomiasis, African/*immunology
Adaptor Proteins, Signal Transducing/genetics ; Adoptive Transfer ; Animals ; Antibody Affinity ; Antibody Formation ; B-Lymphocytes/immunology ; Cytokines/metabolism ; Disease Susceptibility ; Immunoglobulin G/immunology ; Immunoglobulin M/immunology ; Lipoproteins/genetics ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Parasitemia/immunology ; T-Lymphocytes, Regulatory ; Trypanosomiasis, African/parasitology